Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionendopeptidase activity

MEP1B CAPN12 PCSK7 CASP10 ADAMTS5 MMP9

7.77e-05430346GO:0004175
GeneOntologyMolecularFunctionpeptidase activity

MEP1B CAPN12 PCSK7 CASP10 ADAMTS5 DPP8 MMP9

9.74e-05654347GO:0008233
GeneOntologyBiologicalProcesscellular response to cadmium ion

CYBB MMP9 OGG1

4.83e-0543343GO:0071276
DomainMetalloPept_cat_dom

MEP1B ADAMTS5 MMP9

4.27e-0481343IPR024079
Domain-

MEP1B ADAMTS5 MMP9

4.27e-04813433.40.390.10
DomainZINC_PROTEASE

MEP1B ADAMTS5 MMP9

7.45e-0498343PS00142
DomainZnMc

MEP1B MMP9

1.27e-0329342SM00235
DomainPeptidase_Metallo

MEP1B MMP9

1.27e-0329342IPR006026
Pubmed

Meprins process matrix metalloproteinase-9 (MMP-9)/gelatinase B and enhance the activation kinetics by MMP-3.

MEP1B MMP9

5.56e-06434223123160
Pubmed

Macrophage-specific NOX2 contributes to the development of lung emphysema through modulation of SIRT1/MMP-9 pathways.

CYBB MMP9

9.26e-06534225116588
Pubmed

Role of NADPH oxidase-2 in lipopolysaccharide-induced matrix metalloproteinase expression and cell migration.

CYBB MMP9

9.26e-06534219935767
Pubmed

Inhibition of nuclear factor erythroid 2-related factor 2 exacerbates HIV-1 gp120-induced oxidative and inflammatory response: role in HIV associated neurocognitive disorder.

CYBB MMP9

1.39e-05634222528837
Pubmed

Chromosomal location of three unconventional myosin heavy chain genes in the mouse.

MYO1E NCAN

1.39e-0563428954808
Pubmed

Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons.

BCL11B NCAN

1.94e-05734238512724
Pubmed

Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils.

CYBB MMP9

1.94e-05734231600172
Pubmed

Characterization of opticin digestion by proteases involved in osteoarthritis development.

ADAMTS5 MMP9

2.59e-05834223845380
Pubmed

Assignment of a disintegrin and metalloproteinase domain 10 (Adam10) gene to mouse chromosome 9.

PCSK7 MYO1E

2.59e-0583429441766
Pubmed

USP48 Stabilizes Gasdermin E to Promote Pyroptosis in Cancer.

CYBB MMP9 CA1

2.81e-056034336607699
Pubmed

The nuclear cap-binding complex interacts with the U4/U6·U5 tri-snRNP and promotes spliceosome assembly in mammalian cells.

NCBP1 EFTUD2

6.08e-051234223793891
Pubmed

Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy.

CYBB MMP9

6.08e-051234216872848
Pubmed

TRIM24 is an insulin-responsive regulator of P-bodies.

HELZ NCBP1 EFTUD2

6.66e-058034335803934
Pubmed

Unraveling the genetic landscape of bladder development in mice.

BRINP1 MMP9

1.10e-041634219303107
Pubmed

Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.

ADAMTS5 MMP9

1.74e-042034220495570
Pubmed

GATA6 Regulates Aortic Valve Remodeling, and Its Haploinsufficiency Leads to Right-Left Type Bicuspid Aortic Valve.

ADAMTS5 MMP9

2.32e-042334229567669
Pubmed

Dual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formation.

TGM1 BCL11B

2.74e-042534219092943
Pubmed

Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways.

ZFHX3 BCL11B ADAMTS5

2.81e-0413034319386638
Pubmed

Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.

ZFHX3 BCL11B

3.70e-042934231491374
Pubmed

A Large-scale genetic association study of esophageal adenocarcinoma risk.

CASP10 MMP9 SLC22A16 OGG1

3.72e-0435134420453000
Pubmed

Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base.

MMP9 APCDD1

3.97e-043034221911092
Pubmed

ZFP750 affects the cutaneous barrier through regulating lipid metabolism.

TGM1 ELOVL6

4.24e-043134237115925
Pubmed

Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha.

CYBB MMP9

4.52e-04323429611252
Pubmed

PTEN identified as important risk factor of chronic obstructive pulmonary disease.

CYBB TGM1 CASP10 OGG1

4.73e-0437434419625176
Pubmed

Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.

CYBB TGM1 CASP10 OGG1

5.07e-0438134418676680
Pubmed

Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells.

BCL11B NCAN

5.10e-043434231569049
Pubmed

Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.

CYBB TGM1 CASP10 OGG1

5.12e-0438234419170196
Pubmed

Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis.

ADAMTS5 MMP9

6.38e-043834218267097
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

CAPN12 PCSK7 TGM1 DPP8 MMP9

6.75e-0473034534857952
Pubmed

Genetic susceptibility to distinct bladder cancer subphenotypes.

CYBB TGM1 CASP10 OGG1

7.36e-0442134419692168
CytobandEnsembl 112 genes in cytogenetic band chr15q22

DPP8 MYO1E

4.33e-03132342chr15q22
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

CYBB TGM1 MMP9 SH2B2

8.95e-061733448384d533a1071fc65a06e6d9f5f17d8ab00c3966
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCBP1 BCL11B GAMT PARP8

9.36e-0617534406eace2e681980456299167b48bd49bcfea5e940
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CASP10 MMP9 SLC22A16 CA1

1.24e-05188344557a0ac069a6ff4e687cac032f64170b9b247165
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCSK7 NCBP1 BCL11B PARP8

1.27e-051893440e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCell(0)_NK_CD160pos|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CAPN12 HELZ ELOVL6 PARP8

1.27e-05189344713991025bb92d38cb0507ff01fd91b48c8af45a
ToppCell10x5'-lymph-node_spleen-Lymphocytic_NK-NK_CD56bright_CD16-|lymph-node_spleen / Manually curated celltypes from each tissue

CAPN12 HELZ ELOVL6 PARP8

1.40e-051943448a596f25f6bfa5baaa2f52d80ad92f2925713398
ToppCellmild-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HELZ BCL11B ELOVL6 PARP8

1.55e-05199344cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCellLPS_only|World / Treatment groups by lineage, cell group, cell type

MMP9 SLC22A16 SH2B2 CA1

1.55e-05199344852cf595c2255983cff9045f2bb746d4391cf5ba
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD56bright|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CAPN12 ELOVL6 MMP9 PARP8

1.58e-05200344580fbf9fcb78357a081e5f5af06113ca33d44581
ToppCellmild-MAIT|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CAPN12 BCL11B ELOVL6 PARP8

1.58e-052003441e3ef15ce48b9a19a6ac3e08ea0234a9376e6596
ToppCellP15-Hematopoietic|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CYBB BCL11B CA1

1.86e-041463432b3e6ff6069573ee213000aeab5de9a33afc1a99
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BCL11B PARP8 CYP4A22

1.90e-04147343463af96748349c8fec2911b353a7e7e4cb072280
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CYBB ZFHX3 MYO1E

1.94e-04148343fd0d8386b94adb1bdc993fbb44d2d87852bfd7f0
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

PCSK7 BCL11B PARP8

2.05e-04151343999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCellControl-Myeloid-Neutrophils-Neutrophils|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CYBB MMP9 SH2B2

2.14e-04153343e3630f2b10f33092a3b6a63dba3a39fbdecbc7bd
ToppCellControl-Myeloid-Neutrophils|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CYBB MMP9 SH2B2

2.14e-04153343c33d63b2d1a220bc428e776b157b23faa43ea8ca
ToppCellfacs-Lung-Endomucin_-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB TGM1 MMP9

2.30e-041573432b60de520edf167f5ca790b478557a778435b3d9
ToppCelldroplet-Bladder-Unstain-18m-Hematologic-macrophage|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB MMP9 SH2B2

2.35e-04158343e5e7b2d609973f1dd4fe7dc62bb69422268ea801
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TGM1 MMP9 SLC22A16

2.39e-04159343ded4e3626a62fb6334403b7213b467fb7e8131c3
ToppCellIIF-Lymphocyte-T_NK-ILC|IIF / Disease, Lineage and Cell Type

CAPN12 CASP10 ELOVL6

2.39e-0415934355e4f21548f480ca414c00cbff5ec3b13bafd271
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TGM1 MMP9 SLC22A16

2.39e-041593432f6c60ddff2208a68146f9786143d9aefd528840
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP9 NCAN FN3KRP

2.62e-04164343f3772227f5aa75a3672d945f8d5bf3fa0b4e456b
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB ZFHX3 MMP9

2.67e-041653439acf03b5a20170721380045b5c268825e8f315dd
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRC BCL11B MMP9

2.67e-04165343651d40eadb1b34de618af94c167f43635729d43f
ToppCelldroplet-Marrow-BM-30m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB ZFHX3 MMP9

2.71e-04166343019d365df44c3bbd88c1f4bdceb3de0ff76d3e8d
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1B TGM1 ELOVL6

2.76e-04167343ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCellfacs-Heart-LA-3m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCL11B DET1 MMP9

2.81e-0416834316c3313c4186fa327d71215f8eebc31fc12ff1c0
ToppCellfacs-Heart-LA-3m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCL11B DET1 MMP9

2.81e-0416834324d1e0a05cda09ee3b80208d75cb2b601023f3bf
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

BCL11B ELOVL6 PARP8

2.81e-0416834307be11b6f0f37106e219692db5795c6dd32807c9
ToppCellfacs-Heart-LA-3m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCL11B DET1 MMP9

2.81e-04168343b952af95a68888adedd03b1b60836d18524611ab
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CYBB MMP9 SH2B2

2.86e-04169343a0681317867e31319210a23e56660a53f4529efe
ToppCelldroplet-Kidney-nan-18m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1B TGM1 ELOVL6

2.86e-04169343f00741203efa0b948db7223ee8c19bdd0918258a
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYBB PCSK7 SH2B2

2.86e-04169343813472d429c0b12580b17b440e00a6d8beb7947f
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCSK7 BCL11B PARP8

2.86e-0416934320b17f1d6d845213479ade09ea0c7ecc277a73c6
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

ZFHX3 ADAMTS5 APCDD1

2.86e-041693436373562ab3b1765060212a6a53d6543e7e942e80
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HRC ZFHX3 OLFM3

2.91e-041703431f994b690e881106a5d54b3080ccce6260bc3ac5
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

PCSK7 BCL11B PARP8

2.96e-041713432e9a20f8980b78325c52065a9c14ab3656267c05
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB ZFHX3 MMP9

3.01e-04172343d354424c1f861b6607dfd63b9724f4c237b30275
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CYBB MMP9 SH2B2

3.01e-04172343ac20766d1fd43eab8c3ff5e7418a6b38bebf0bd5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CYBB MMP9 SH2B2

3.01e-041723433fd1bc4a8ced0bf9e26ca4ce6d83b5b97bbc2556
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HRC ZFHX3 GAMT

3.11e-04174343778e0317c0c63fa4efd74114feb760975b819d92
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

BCL11B ELOVL6 PARP8

3.11e-0417434333d6b81f31bfcb9c4b30206d88e20b9a94fba4a2
ToppCell10x5'-blood-Lymphocytic_Invariant-Inducer-like-MAIT|blood / Manually curated celltypes from each tissue

CAPN12 ELOVL6 PARP8

3.17e-04175343b4e4b66e89f79999768a6192c8404cb2465f920b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX3 BCL11B OLFM3

3.27e-041773434c069f0d044a96118090b85ca592a21d6b5d9399
ToppCellnormal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ|normal_Lymph_Node / Location, Cell class and cell subclass

MYO1E OGG1 SH2B2

3.33e-04178343d75057e7463558a0d3cebde3c30befbf4704dd9a
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BCL11B ELOVL6 PARP8

3.38e-04179343b0585a8e596c3d8e434af943e65207fa5877600d
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

ZFHX3 ADAMTS5 APCDD1

3.38e-04179343dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellASK440-Immune-NK_cell|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

PCSK7 BCL11B ELOVL6

3.44e-04180343340e750356d23fe9af0e8f298f8a273ff426052f
ToppCellSevere-Lymphoid-T-innate_T|Severe / Condition, Lineage, Cell class and cell subclass

BCL11B ELOVL6 PARP8

3.50e-0418134350ab8562552339d97e4f19aa6ae49fd797da492e
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

PCSK7 BCL11B PARP8

3.50e-04181343f2315414e714ac86211546a935660c4be6e85f1b
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CYBB MMP9 SLC22A16

3.50e-041813433457c1d431db4282be5a6243119e48960748ede7
ToppCellPericytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

HRC ZFHX3 ADAMTS5

3.55e-0418234346c213597445b1f4f09dc367f27702d24b201daf
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN12 HRC ZFHX3

3.55e-04182343ffe500d78a89dc6b4d05bab1664e7f30c94fb8d9
ToppCellmetastatic_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ|metastatic_Lymph_Node / Location, Cell class and cell subclass

MYO1E OGG1 SH2B2

3.61e-0418334330db83f600e2c4ad3af68a8a946673f4352a2807
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-CD8_TRM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK7 BCL11B PARP8

3.67e-0418434317ffa0e890960c00a3b5fa33d48caba66c61dbb0
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN12 HRC ZFHX3

3.67e-0418434394748f63947db79a6b4540e3090a63689fdd9452
ToppCellT_cells-Resident_memory_CD8+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CAPN12 BCL11B PARP8

3.67e-04184343e04cabff33a8e36967622ec3e5b37b89afa7e148
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN12 HRC ZFHX3

3.67e-04184343819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WFDC8 BCL11B MYO1E

3.73e-04185343e87e6e097dc29ece8aea671935bde281b99b93ea
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HRC BCL11B ADAMTS5

3.79e-04186343948815663c212c4311329d503b5991cbbbff9808
ToppCellfacs-Skin-Anagen-24m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS5 ELOVL6 FN3KRP

3.85e-04187343908df5520142d65fe32a003d26be14965082a1ea
ToppCellfacs-Skin-Anagen-24m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS5 ELOVL6 FN3KRP

3.85e-04187343c1dfab0b0d7f519b9f13f4e0365ab41c4b2ae1ec
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

ZFHX3 ADAMTS5 APCDD1

3.85e-041873434ea486991f66c29728d127171a07b81404ec0b78
ToppCellfacs-Skin-Anagen-24m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS5 ELOVL6 FN3KRP

3.85e-04187343b486cc5ac678051fea9d4c7db53b26a5a8427e60
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TGM1 BRINP1 ADAMTS5

3.85e-041873438e8f1f2a78ac5f13a414fd448af7d7ff1ea86f0f
ToppCellE17.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HRC ZFHX3 GAMT

3.85e-041873430dee138738b65531ff134a125b92234b5d0a653c
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_NK-NK_CD56bright_CD16-|lymph-node_spleen / Manually curated celltypes from each tissue

CAPN12 HELZ ELOVL6

3.85e-041873439000241566f48e435db9409b7255db68b68f6059
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRC ZFHX3 ADAMTS5

3.91e-04188343d1a4cd4db95d8d32b79156290f7867f32824cc87
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BCL11B ADAMTS5 CA1

3.91e-041883433139540a656c0436b2123ea50741ff8d00112165
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HRC BCL11B ADAMTS5

3.97e-0418934378cf414b98bcb19deb934409acddaad1cd51b67f
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Erythrocyte|World / Lineage, cell class and subclass

ELOVL6 SLC22A16 CA1

3.97e-04189343826457adac7477102f86aceb97a8b77929b3e6f9
ToppCellNS-critical-d_0-4-Lymphoid-CTL|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PCSK7 BCL11B PARP8

3.97e-04189343fb7572fb4c7c43886d57a025decad076f32a14c4
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRC ZFHX3 ADAMTS5

4.03e-041903431803b1e7c36285f9eaabc3c6e9a9752c5908db3d
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

ZFHX3 ADAMTS5 APCDD1

4.03e-0419034312992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BCL11B ELOVL6 PARP8

4.03e-0419034305e6af222d0ad97cb69f399a96c9038f9dd989b9
ToppCellMegakaryocytic-erythropoietic-Erythro-cells|World / Lineage, cell class and subclass

ELOVL6 SLC22A16 CA1

4.03e-041903436c7e016a9b425ee9418acd4fe96b9779fe7bd39a
ToppCellIPF-Lymphoid-T|IPF / Disease state, Lineage and Cell class

BCL11B ELOVL6 PARP8

4.03e-04190343d57df208aaf7a5554899bb9107c80b443fd0cf93
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRC ZFHX3 ADAMTS5

4.09e-041913438597a8af294f24496c317d995f07eb5dcc25c13c
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

ZFHX3 ADAMTS5 APCDD1

4.09e-04191343d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

ZFHX3 ADAMTS5 APCDD1

4.09e-0419134370c067c54084bfb02c29bab085f4defd477194fb
ToppCellURO-Lymphocyte-T_NK-CD8_TEM|URO / Disease, Lineage and Cell Type

PCSK7 BCL11B PARP8

4.15e-0419234331b6d068f7adc6952c4cf625df851a10cb1b00c9
ToppCellControl-Lymphoid-T|World / Disease state, Lineage and Cell class

BCL11B ELOVL6 PARP8

4.15e-04192343253cf4d2cf88ad8c45b73779336180840bef054b
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HRC ZFHX3 GAMT

4.15e-04192343dee97f650ae6f4d07a142ade402aae1905791a22
ToppCellcritical-Lymphoid-CTL|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PCSK7 BCL11B PARP8

4.15e-041923438c83050c1578d43ca0398ff920f30ea63f092a83
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRC ZFHX3 ADAMTS5

4.15e-041923433617d2bc7e33d981f3ec349e9962d8d4bd822fbd
ToppCellCOPD-Lymphoid-T|World / Disease state, Lineage and Cell class

BCL11B ELOVL6 PARP8

4.15e-04192343eb4909574fb5fc91399463523e2737095773200a
ToppCellIPF-Lymphoid-T|World / Disease state, Lineage and Cell class

BCL11B ELOVL6 PARP8

4.15e-04192343b25ba1f3bc842c22602b2aeed3b1b5082863e4fa
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PCSK7 BCL11B PARP8

4.15e-04192343ed1fb700d3e8f00495727d61e164fc0b70274fd0
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HRC ZFHX3 ADAMTS5

4.15e-0419234326d9207e72bbef5e0046de511e2c9ff752b726f3
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PCSK7 BCL11B PARP8

4.15e-041923436779b0294bb058e748e22b795b6a381c4add37e9
ToppCellcontrol-Lymphoid-CTL|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PCSK7 BCL11B PARP8

4.22e-0419334389d407a88b5956559a589425b89b3eb8dc78e1dd
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HRC ZFHX3 GAMT

4.22e-04193343469a7f1c2ff7137cc5a064464456911f67f92e70
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

ZFHX3 ADAMTS5 APCDD1

4.22e-04193343dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCSK7 BCL11B PARP8

4.22e-041933437022b3ce6220d6d1722a4e2947630a8da002cdce
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCSK7 BCL11B PARP8

4.22e-041933433083305b7ae09a37d7f45b915d49b2b396276822
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCSK7 BCL11B PARP8

4.22e-041933431218e74ee5e00d230222b10acc50cb96201016b4
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HRC ZFHX3 GAMT

4.22e-04193343323d1f3f4fbeb93ba857fc135d8aa0b897f98ac5
ToppCellControl-Lymphoid-T|Control / Disease state, Lineage and Cell class

BCL11B ELOVL6 PARP8

4.22e-04193343af928046ccd1ca874be1534aef6ca7f27d90bc46
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK-CD56_bright_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CAPN12 BCL11B PARP8

4.22e-0419334346f94a1062b098205e8ce3ed380c0202a4d97678
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

BCL11B ELOVL6 PARP8

4.22e-041933431cb666375bc4e1b11a146d20896c9b5ae6fd0887
DrugAC1Q6PMP

CAPN12 PCSK7 CASP10 MMP9 EFTUD2

4.96e-06169345CID000103535
DrugKetanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; PC3; HT_HG-U133A

MEP1B CASP10 BRINP1 BCL11B CA1

1.05e-051973456649_UP
DrugBezafibrate [41859-67-0]; Up 200; 11uM; PC3; HT_HG-U133A

MEP1B NCBP1 ELOVL6 MMP9 OGG1

1.05e-051973456653_UP
DiseasePremature Birth

MMP9 OGG1

6.63e-0511332C0151526
DiseaseObesity

ZFHX3 MMP9 APCDD1 OGG1

7.91e-05205334C0028754
Diseaserenal fibrosis (biomarker_via_orthology)

CYBB MMP9

7.95e-0512332DOID:0050855 (biomarker_via_orthology)
DiseaseHyperplasia

MMP9 OGG1

4.50e-0428332C0020507
DiseaseNEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE

NUP133 MYO1E

5.17e-0430332C1868672
Diseaseosteoarthritis (is_marker_for)

ADAMTS5 MMP9

7.05e-0435332DOID:8398 (is_marker_for)
DiseaseLymphoma

BCL11B OGG1

9.21e-0440332C0024299
Diseasepre-eclampsia (is_marker_for)

MMP9 GAMT

1.93e-0358332DOID:10591 (is_marker_for)
DiseaseMalignant neoplasm of skin

CASP10 MMP9

1.99e-0359332C0007114
DiseaseSkin Neoplasms

CASP10 MMP9

1.99e-0359332C0037286
Diseasehypertension (biomarker_via_orthology)

CYBB MMP9 CYP4A22

2.07e-03227333DOID:10763 (biomarker_via_orthology)
Diseaserheumatoid arthritis (is_marker_for)

ADAMTS5 MMP9

2.72e-0369332DOID:7148 (is_marker_for)
DiseaseLiver diseases

TGM1 MMP9

2.95e-0372332C0023895
DiseaseLiver Dysfunction

TGM1 MMP9

2.95e-0372332C0086565

Protein segments in the cluster

PeptideGeneStartEntry
HFLTIGSIHQHWGND

BRINP1

321

O60477
FCKWQHQHNQLGDDH

ADAMTS5

341

Q9UNA0
KAGTHWHQVRVFHQN

DET1

31

Q7L5Y6
RFQTFEGDLKWHHHN

MMP9

106

P14780
ANFLQAHEHLSWLHE

NUP133

926

Q8WUM0
GSTFAFHGSHIENWH

PARP8

691

Q8N3A8
DRFINWFSHHLSNFQ

NCBP1

411

Q09161
QLFHYLNHWNHFGSG

FN3KRP

281

Q9HA64
FSHSHQHGFGLLNAW

PCSK7

456

Q16549
HHWGSVDSHFQEVAQ

OGG1

111

O15527
QQWSEHHAFLSQGSA

HELZ

1516

P42694
QHDQCHSHFQNIFWS

ELOVL6

221

Q9H5J4
HGQSLALHHFQQLWG

CAPN12

606

Q6ZSI9
NSAWFLLQHAQNTHG

BCL11B

231

Q9C0K0
LFQFHFHWGSTNEHG

CA1

91

P00915
SHWLFGHIQEFQHDQ

CYP4A22

56

Q5TCH4
WINIHDIFHVFPQSH

DPP8

446

Q6V1X1
RHFIFHDNNNTWEGH

APCDD1

311

Q8J025
TGWDESQANHFAVHH

CYBB

481

P04839
EETWHTHQFNFIKNH

GAMT

141

Q14353
SHVFQWLGFTVHIHN

CASP10

311

Q92851
QHEFLHALGFWHEQS

MEP1B

151

Q16820
WNNGHQVLFNVTLFH

OLFM3

456

Q96PB7
GRQFFHLHWHFLNSA

TAS2R41

81

P59536
GNVSQVVFHNHSNWS

SLC22A16

56

Q86VW1
EHSFINSFGHENTWI

NCAN

1131

O14594
NKDVSTENGHHFWSH

HRC

71

P23327
HGNCNHEAQRWHFDF

WFDC8

101

Q8IUA0
LNGHGQCHVQHLWFQ

SH2B2

471

O14492
HLNHDSVWNFHVWND

TGM1

426

P22735
TQGQAFSLSVFHHWQ

EFTUD2

891

Q15029
HHFEFQWQEVERNGH

ZNF816

111

Q0VGE8
SFEHWQEHQQLHFLS

ZFHX3

2541

Q15911
SHEHFNSWNQGFIIH

MYO1E

491

Q12965