Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	Fc-gamma receptor I complex binding	IGHG2 IGHG3 IGHG4	1.26e-05	7	144	3	GO:0034988
GeneOntologyMolecularFunction	IMP dehydrogenase activity	IMPDH1 IMPDH2	5.16e-05	2	144	2	GO:0003938
GeneOntologyBiologicalProcess	positive regulation of type I hypersensitivity	IGHG2 IGHG3 IGHG4	1.86e-05	8	145	3	GO:0001812
GeneOntologyBiologicalProcess	regulation of type I hypersensitivity	IGHG2 IGHG3 IGHG4	2.77e-05	9	145	3	GO:0001810
GeneOntologyBiologicalProcess	regulation of meiosis I	PIWIL2 WEE2 KNL1	2.77e-05	9	145	3	GO:0060631
GeneOntologyBiologicalProcess	positive regulation of type IIa hypersensitivity	IGHG2 IGHG3 IGHG4	3.94e-05	10	145	3	GO:0001798
GeneOntologyBiologicalProcess	type I hypersensitivity	IGHG2 IGHG3 IGHG4	3.94e-05	10	145	3	GO:0016068
GeneOntologyBiologicalProcess	positive regulation of type II hypersensitivity	IGHG2 IGHG3 IGHG4	3.94e-05	10	145	3	GO:0002894
GeneOntologyBiologicalProcess	regulation of type IIa hypersensitivity	IGHG2 IGHG3 IGHG4	5.39e-05	11	145	3	GO:0001796
GeneOntologyBiologicalProcess	regulation of type II hypersensitivity	IGHG2 IGHG3 IGHG4	5.39e-05	11	145	3	GO:0002892
GeneOntologyBiologicalProcess	antibody-dependent cellular cytotoxicity	IGHG2 IGHG3 IGHG4	9.24e-05	13	145	3	GO:0001788
GeneOntologyBiologicalProcess	cellular response to epinephrine stimulus	AKAP6 RYR2 PKLR	1.17e-04	14	145	3	GO:0071872
GeneOntologyBiologicalProcess	type IIa hypersensitivity	IGHG2 IGHG3 IGHG4	1.46e-04	15	145	3	GO:0001794
GeneOntologyBiologicalProcess	positive regulation of hypersensitivity	IGHG2 IGHG3 IGHG4	1.46e-04	15	145	3	GO:0002885
GeneOntologyBiologicalProcess	type II hypersensitivity	IGHG2 IGHG3 IGHG4	1.46e-04	15	145	3	GO:0002445
GeneOntologyBiologicalProcess	phagocytosis, recognition	LBP IGHG2 IGHG3 IGHG4	2.13e-04	42	145	4	GO:0006910
GeneOntologyBiologicalProcess	positive regulation of acute inflammatory response to antigenic stimulus	IGHG2 IGHG3 IGHG4	2.15e-04	17	145	3	GO:0002866
GeneOntologyBiologicalProcess	response to epinephrine	AKAP6 RYR2 PKLR	2.15e-04	17	145	3	GO:0071871
GeneOntologyBiologicalProcess	plasma membrane invagination	LBP IGHG2 IGHG3 IGHG4 AURKB	2.24e-04	78	145	5	GO:0099024
GeneOntologyBiologicalProcess	cytoskeleton-dependent cytokinesis	ANK3 SEPTIN5 CECR2 USP8 SON AURKB	2.80e-04	127	145	6	GO:0061640
GeneOntologyBiologicalProcess	negative regulation of barbed-end actin filament capping	CARMIL2 CARMIL1	2.92e-04	4	145	2	GO:2000813
GeneOntologyBiologicalProcess	regulation of hypersensitivity	IGHG2 IGHG3 IGHG4	3.04e-04	19	145	3	GO:0002883
GeneOntologyBiologicalProcess	membrane invagination	LBP IGHG2 IGHG3 IGHG4 AURKB	3.73e-04	87	145	5	GO:0010324
GeneOntologyCellularComponent	IgG immunoglobulin complex	IGHG2 IGHG3 IGHG4	1.15e-04	14	146	3	GO:0071735
GeneOntologyCellularComponent	immunoglobulin complex, circulating	IGHG2 IGHG3 IGHG4	2.11e-04	17	146	3	GO:0042571
GeneOntologyCellularComponent	sarcoplasmic reticulum	AKAP6 HK2 ANK3 CMYA5 RYR2	3.82e-04	88	146	5	GO:0016529
GeneOntologyCellularComponent	transferase complex	UBR2 EPC2 RANBP2 ERN1 EP400 DBF4B KAT6A FBXL12 FBXW4 CUL9 RB1CC1 YEATS2 AKAP4 PIK3R6 CCNB3 PKLR MAP3K7	4.09e-04	963	146	17	GO:1990234
GeneOntologyCellularComponent	histone acetyltransferase complex	EPC2 EP400 KAT6A YEATS2 MAP3K7	5.17e-04	94	146	5	GO:0000123
GeneOntologyCellularComponent	interphotoreceptor matrix	VCAN IMPG2	7.13e-04	6	146	2	GO:0033165
GeneOntologyCellularComponent	protein acetyltransferase complex	EPC2 EP400 KAT6A YEATS2 MAP3K7	8.19e-04	104	146	5	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	EPC2 EP400 KAT6A YEATS2 MAP3K7	1.01e-03	109	146	5	GO:1902493
GeneOntologyCellularComponent	sarcoplasm	AKAP6 HK2 ANK3 CMYA5 RYR2	1.24e-03	114	146	5	GO:0016528
GeneOntologyCellularComponent	intercalated disc	AKAP6 ANK3 DST TLN2	1.31e-03	68	146	4	GO:0014704
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	EPC2 EP400 YEATS2	1.43e-03	32	146	3	GO:0035267
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	EPC2 EP400 YEATS2	1.43e-03	32	146	3	GO:0043189
MousePheno	absent memory B cells	IGHG2 IGHG3 IGHG4	2.71e-06	4	124	3	MP:0008094
Domain	IMP_DH	IMPDH1 IMPDH2	6.07e-05	2	146	2	IPR005990
Domain	SEA	MUC16 MUC17 IMPG2	1.60e-04	14	146	3	SM00200
Domain	Pyrv/PenolPyrv_Kinase-like_dom	CLYBL PKLR	1.81e-04	3	146	2	IPR015813
Domain	CARMIL_C	CARMIL2 CARMIL1	1.81e-04	3	146	2	IPR031943
Domain	-	CLYBL PKLR	1.81e-04	3	146	2	3.20.20.60
Domain	CARMIL_C	CARMIL2 CARMIL1	1.81e-04	3	146	2	PF16000
Domain	-	MUC16 MUC17 IMPG2	1.99e-04	15	146	3	3.30.70.960
Domain	HSA	EP400 SRCAP	3.60e-04	4	146	2	SM00573
Domain	IMPDH	IMPDH1 IMPDH2	3.60e-04	4	146	2	PF00478
Domain	IMP_DH_GMPRt	IMPDH1 IMPDH2	3.60e-04	4	146	2	IPR001093
Domain	HSA	EP400 SRCAP	3.60e-04	4	146	2	PS51204
Domain	IMP_DH_GMP_RED	IMPDH1 IMPDH2	3.60e-04	4	146	2	PS00487
Domain	IMP_DH/GMP_Rdtase_CS	IMPDH1 IMPDH2	3.60e-04	4	146	2	IPR015875
Domain	HSA_dom	EP400 SRCAP	3.60e-04	4	146	2	IPR014012
Domain	HSA	EP400 SRCAP	3.60e-04	4	146	2	PF07529
Domain	Pyrv_Knase-like_insert_dom	PKLR MTARC1	5.98e-04	5	146	2	IPR011037
Domain	SEA	MUC16 MUC17 IMPG2	6.46e-04	22	146	3	PF01390
Domain	SEA	MUC16 MUC17 IMPG2	7.39e-04	23	146	3	PS50024
Domain	SEA_dom	MUC16 MUC17 IMPG2	7.39e-04	23	146	3	IPR000082
Domain	ITI_HC_C	ITIH3 ITIH4	8.92e-04	6	146	2	IPR010600
Domain	GAR	GAS2L1 DST	8.92e-04	6	146	2	PS51460
Domain	GAS2	GAS2L1 DST	8.92e-04	6	146	2	PF02187
Domain	-	GAS2L1 DST	8.92e-04	6	146	2	3.30.920.20
Domain	GAS_dom	GAS2L1 DST	8.92e-04	6	146	2	IPR003108
Domain	ITI_HC_C	ITIH3 ITIH4	8.92e-04	6	146	2	PF06668
Domain	GAS2	GAS2L1 DST	8.92e-04	6	146	2	SM00243
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	EPC2 WDR36 EP400 DDX52 GTSE1 JMJD1C YEATS2 ZC3H11A TOX4 SPEN TASOR KNL1 AURKB	2.67e-09	339	148	13	30415952
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	RANBP2 JMJD1C RYR2 YEATS2 MRTFB DST MDC1 ELP4 PDZD2	3.12e-09	123	148	9	26912792
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	RANBP2 RAPGEF6 WDR36 IMPDH2 EP400 ATAD5 CARMIL1 SRCAP YEATS2 USP8 ZC3H11A TOX4 MRTFB DST R3HCC1L NCOA7 TASOR KNL1 PPP6R3 SON	3.33e-09	934	148	20	33916271
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBR2 EP400 MARK3 RAP1GAP2 CUL9 MED13L YEATS2 USP8 ZC3H11A SPEN AQR SON PDZD2	2.34e-08	407	148	13	12693553
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	WDR36 ANK3 EP400 PSMA5 MUC16 SNAP47 RYR2 CDKL5 FAT1 ZC3H11A DST OCIAD1 PKLR ZFHX3 MAP3K7 SPEN TASOR	4.03e-08	777	148	17	35844135
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	EPC2 EP400 ATAD5 DDX52 CECR2 KAT6A GATA4 CUL9 SRCAP ITIH4 YEATS2 FAT1 CCNB3 ZFHX3 PDZRN3 UNC80 KNL1 SON AURKB ZNF646	6.32e-08	1116	148	20	31753913
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	RAPGEF6 ANK3 EP400 SRCAP JMJD1C YEATS2 ZC3H11A TOX4 MRTFB MDC1 SPEN ELP4 SNX2 PPP6R3	1.08e-07	549	148	14	38280479
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	UBR2 EPC2 RANBP2 HK2 EP400 DDX52 PSMA5 GTSE1 GATA4 ID2 CUL9 RUNX1T1 TRIM29 JMJD1C ZC3H11A SPEN SNX2	1.62e-07	857	148	17	25609649
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	GTSE1 DUSP6 KAT6A ZC3H11B SLC25A37 YEATS2 FAT1 ZC3H11A TOX4 DST SON	2.03e-07	332	148	11	37433992
Pubmed	Sequence analysis of cloned cDNA encoding part of an immunoglobulin heavy chain.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	113776
Pubmed	Highly specific anti-estradiol antibodies: structural characterisation and binding diversity.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	11812141
Pubmed	Multiple amino acid substitutions between murine gamma 2a heavy chain Fc regions of Ig1a and Ig1b allotypic forms.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6794027
Pubmed	Further evidence that BALB/c and C57BL/6 gamma 2a genes originate from two distinct isotypes.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	2510996
Pubmed	Spontaneous deletions in Ig heavy chain genes: flanking sequences influence splice site selection.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	1754385
Pubmed	Sialic acid residues are essential for the anaphylactic activity of murine IgG1 antibodies.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	19050247
Pubmed	An autoimmune disease variant of IgG1 modulates B cell activation and differentiation.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	30287618
Pubmed	Switch transcripts in immunoglobulin class switching.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	7892607
Pubmed	Determination of the primary structure of a mouse G2a immunoglobulin. Identification of the disulfide bridges.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	4565406
Pubmed	IgG1 protects against renal disease in a mouse model of cryoglobulinaemia.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	25363774
Pubmed	Mutational deglycosylation of the Fc portion of immunoglobulin G causes O-sulfation of tyrosine adjacently preceding the originally glycosylated site.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	20621099
Pubmed	Antibody epitopes on the neuraminidase of a recent H3N2 influenza virus (A/Memphis/31/98).	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	12414967
Pubmed	Shutdown of class switch recombination by deletion of a switch region control element.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	8438159
Pubmed	Passive anaphylaxis in mice with gamma-G antibodies. V. Competitive effects of different immunoglobulins and inhibition of reactions with antiglobulin sera.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	4098598
Pubmed	Mouse immunoglobulin genes: a bacterial plasmid containing the entire coding sequence for a pre-gamma 2a heavy chain.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6253932
Pubmed	Immunoglobulin gamma 1 heavy chain gene: structural gene sequences cloned in a bacterial plasmid.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6769752
Pubmed	Mouse immunoglobulin allotypes: post-duplication divergence of gamma 2a and gamma 2b chain genes.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6803173
Pubmed	Linkage of the four gamma subclass heavy chain genes.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6264445
Pubmed	Sequences near the 3' secretion-specific polyadenylation site influence levels of secretion-specific and membrane-specific IgG2b mRNA in myeloma cells.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	2878362
Pubmed	IgG1 deficiency exacerbates experimental autoimmune myasthenia gravis in BALB/c mice.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	25867470
Pubmed	Sequence of the gamma 2b membrane 3' untranslated region: polya site determination and comparison to the gamma 2a membrane 3' untranslated region.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	1542303
Pubmed	Switch of CD4+ T cell differentiation from Th2 to Th1 by treatment with cathepsin B inhibitor in experimental leishmaniasis.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	9725203
Pubmed	Nucleotide sequences of all the gamma gene loci of murine immunoglobulin heavy chains.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	9126488
Pubmed	The IL-4 induced increase in the frequency of resting murine splenic B cells expressing germline Ig heavy chain gamma 1 transcripts correlates with subsequent switching to IgG1.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	8452816
Pubmed	Determination of the primary structure of a mouse IgG2a immunoglobulin:amino-acid sequence of the Fc fragment. Implications for the evolution of immunoglobulin structure and function.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	4831970
Pubmed	Nucleotide sequences of class-switch recombination region of the mouse immunoglobulin gamma 2b-chain gene.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	7439686
Pubmed	On immunoglobulin heavy chain gene switching: two gamma 2b genes are rearranged via switch sequences in MPC-11 cells but only one is expressed.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6278424
Pubmed	An Asia-specific variant of human IgG1 represses colorectal tumorigenesis by shaping the tumor microenvironment.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	35133976
Pubmed	Restriction fragment length polymorphism and evolution of the mouse immunoglobulin constant region gamma loci.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	8099342
Pubmed	Ubiquitination of IgG1 cytoplasmic tail modulates B-cell signalling and activation.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	32006024
Pubmed	Strong antigenic selection shaping the immunoglobulin heavy chain repertoire of B-1a lymphocytes in lambda 2(315) transgenic mice.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	12209645
Pubmed	Sequence of the cloned gene for the constant region of murine gamma 2b immunoglobulin heavy chain.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	117549
Pubmed	Cloning immunoglobulin gamma 2b chain gene of mouse: characterization and partial sequence determination.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	116231
Pubmed	Highly reduced binding to high and low affinity mouse Fc gamma receptors by L234A/L235A and N297A Fc mutations engineered into mouse IgG2a.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	25451975
Pubmed	Nucleotide sequences of gene segments encoding membrane domains of immunoglobulin gamma chains.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6283537
Pubmed	Somatic mutation in genes for the variable portion of the immunoglobulin heavy chain.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6801765
Pubmed	Immunoglobulin diversity: analysis of the germ-line VH gene repertoire of the murine anti-GAT response.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6306571
Pubmed	The molecular and biochemical characterization of mutant monoclonal antibodies with increased antigen binding.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	1672339
Pubmed	Recognition of a cell-surface oligosaccharide of pathogenic Salmonella by an antibody Fab fragment.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	1713710
Pubmed	Structure of the constant and 3' untranslated regions of the murine Balb/c gamma 2a heavy chain messenger RNA.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6777755
Pubmed	The roles of gamma 1 heavy chain membrane expression and cytoplasmic tail in IgG1 responses.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	9103199
Pubmed	Gene conversion and polymorphism: generation of mouse immunoglobulin gamma 2a chain alleles by differential gene conversion by gamma 2b chain gene.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6297797
Pubmed	Evolution of immunoglobulin subclasses. Primary structure of a murine myeloma gamma1 chain.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	98524
Pubmed	Immunoglobulin heavy constant gamma 1 silencing decreases tonicity-responsive enhancer-binding protein expression to alleviate diabetic nephropathy.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	38268239
Pubmed	Gene segments encoding transmembrane carboxyl termini of immunoglobulin gamma chains.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6799207
Pubmed	Comparison of mouse immunoglobulin gamma 2a and gamma 2b chain genes suggests that exons can be exchanged between genes in a multigenic family.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6787604
Pubmed	Multiple differences between the nucleic acid sequences of the IgG2aa and IgG2ab alleles of the mouse.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6170065
Pubmed	Distinction of the memory B cell response to cognate antigen versus bystander inflammatory signals.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	19703988
Pubmed	Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6767246
Pubmed	Determination of the interface of a large protein complex by transferred cross-saturation measurements.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	12051834
Pubmed	The gamma 1 heavy chain gene includes all of the cis-acting elements necessary for expression of properly regulated germ-line transcripts.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	8683112
Pubmed	Genes for immunoglobulin heavy chain and serum prealbumin protein are linked in mouse.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	807855
Pubmed	Identification of a gene locus for gamma-G-1 immunoglobulin H chains and its linkage to the H chain chromosome region in the mouse.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	4166666
Pubmed	Multiple B-cell epitope vaccine induces a Staphylococcus enterotoxin B-specific IgG1 protective response against MRSA infection.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	26201558
Pubmed	Molecular cloning of mouse immunoglobulin heavy chain messenger ribonucleic acids coding for mu, alpha, gamma 1, gamma 2a, and gamma 3 chains.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6249338
Pubmed	mRNA for surface immunoglobulin gamma chains encodes a highly conserved transmembrane sequence and a 28-residue intracellular domain.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6804950
Pubmed	Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	19592272
Pubmed	Attenuation of Trypanosoma brucei is associated with reduced immunosuppression and concomitant production of Th2 lymphokines.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	10720538
Pubmed	Elucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	24752300
Pubmed	Variable-region-identical antibodies differing in isotype demonstrate differences in fine specificity and idiotype.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	15699144
Pubmed	Sequence and polyadenylation site determination of the murine immunoglobulin gamma 2a membrane 3' untranslated region.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	2513486
Pubmed	Increased number of T cells and exacerbated inflammatory pathophysiology in a human IgG4 knock-in MRL/lpr mouse model.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	36763580
Pubmed	Independent immunoglobulin class-switch events occurring in a single myeloma cell line.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	3921826
Pubmed	The complete nucleotide sequence of mouse immunoglobin gamma 2a gene and evolution of heavy chain genes: further evidence for intervening sequence-mediated domain transfer.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6262729
Pubmed	Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	26683050
Pubmed	Complete nucleotide sequence of immunoglobulin gamma2b chain gene cloned from newborn nouse DNA.	IGHG2 IGHG3 IGHG4	3.01e-07	4	148	3	6766534
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	AKAP6 UBR2 SRCAP TLN2 RIMS1 PDZD2 ZNF646	3.30e-07	104	148	7	9205841
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RANBP2 WDR36 IMPDH1 IMPDH2 EP400 SEPTIN5 ATAD5 MARK3 DDX52 NDUFA7 ZC3H11A MRTFB DST MDC1 IMP4 ZFHX3 DNAJC1 SPEN TASOR AQR PPP6R3 SON	4.03e-07	1497	148	22	31527615
Pubmed	Exon shuffling generates an immunoglobulin heavy chain gene.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	6769120
Pubmed	Chromosomal location of the structural gene cluster encoding murine immunoglobulin heavy chains.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	6770027
Pubmed	Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	7704573
Pubmed	Channel catfish soluble FcmuR binds conserved linear epitopes present on Cmu3 and Cmu4.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	20031218
Pubmed	A novel allele for inducible Cre expression in germinal center B cells.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	30359469
Pubmed	FcgammaRIII (CD16)-deficient mice show IgG isotype-dependent protection to experimental autoimmune hemolytic anemia.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	9834201
Pubmed	The synthesis and processing of the messenger RNAs specifying heavy and light chain immunoglobulins in MPC-11 cells.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	103631
Pubmed	CCAAT/enhancer binding protein β Induces Post-Switched B Cells to Produce Blimp1 and Differentiate into Plasma Cells.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	33163250
Pubmed	Protein arginine methyltransferase 1 regulates B cell fate after positive selection in the germinal center in mice.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	37310381
Pubmed	Mouse models of human multiple myeloma subgroups.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	36853944
Pubmed	IgE knock-in mice suggest a role for high levels of IgE in basophil-mediated active systemic anaphylaxis.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	23423996
Pubmed	The disulphide bridges of a mouse immunoglobulin G1 protein.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	5073237
Pubmed	Preneoplastic somatic mutations including MYD88L265P in lymphoplasmacytic lymphoma.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	35044826
Pubmed	Sequential class switching is required for the generation of high affinity IgE antibodies.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	22249450
Pubmed	The FOXO1 Transcription Factor Instructs the Germinal Center Dark Zone Program.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	26620759
Pubmed	Expression of NrasQ61R and MYC transgene in germinal center B cells induces a highly malignant multiple myeloma in mice.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	32640012
Pubmed	Serine-threonine kinase ROCK2 regulates germinal center B cell positioning and cholesterol biosynthesis.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	32229726
Pubmed	Brg1 Supports B Cell Proliferation and Germinal Center Formation Through Enhancer Activation.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	34539636
Pubmed	Rate of replication of the murine immunoglobulin heavy-chain locus: evidence that the region is part of a single replicon.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	3031474
Pubmed	Functional humanization of immunoglobulin heavy constant gamma 1 Fc domain human FCGRT transgenic mice.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	33025844
Pubmed	Evidence that High-Affinity IgE Can Develop in the Germinal Center in the Absence of an IgG1-Switched Intermediate.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	36779803
Pubmed	Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	6798155
Pubmed	IgG1 cytoplasmic tail is essential for cell surface expression in Igβ down-regulated cells.	IGHG2 IGHG3 IGHG4	7.50e-07	5	148	3	24548411
Interaction	NUP43 interactions	RANBP2 CENPT WDR36 EP400 SRCAP JMJD1C RYR2 YEATS2 MRTFB DST MDC1 ZFHX3 SPEN ELP4 KNL1 SON PDZD2	2.69e-06	625	145	17	int:NUP43
Interaction	RCOR1 interactions	RANBP2 RAPGEF6 RB1CC1 JMJD1C YEATS2 TOX4 MRTFB DST ZFHX3 SPEN TASOR KNL1 PPP6R3 AURKB	1.37e-05	494	145	14	int:RCOR1
Interaction	IGHV4-31 interactions	IGHG2 IGHG3 IGHG4	1.99e-05	8	145	3	int:IGHV4-31
Interaction	MEX3A interactions	RAP1GAP GTSE1 DUSP6 KAT6A ZC3H11B SLC25A37 YEATS2 FAT1 ZC3H11A TOX4 DST SON	2.24e-05	384	145	12	int:MEX3A
Interaction	NAA40 interactions	RANBP2 RAPGEF6 WDR36 IMPDH2 EP400 ATAD5 CARMIL1 SRCAP YEATS2 USP8 ZC3H11A TOX4 MRTFB DST R3HCC1L NCOA7 TASOR KNL1 PPP6R3 SON	2.40e-05	978	145	20	int:NAA40
Interaction	H2BC21 interactions	EPC2 EP400 ATAD5 DBF4B DDX52 PSMA5 KAT6A SRCAP JMJD1C YEATS2 USP8 TOX4 MRTFB MDC1 TOP3A AURKB	4.25e-05	696	145	16	int:H2BC21
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	AKAP6 DOK6 RAPGEF6 SLC4A8 ANK3 TSHZ2 RAP1GAP2 CHGA MED13L RB1CC1 RUNX1T1 RYR2 VCAN CNTN5 PLXNA4 NCOA7 TLN2 ZFHX3 RIMS1 UNC79 CNTN1	1.14e-06	1106	148	21	M39071
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOK6 PAG1 MYLK SEPTIN5 RYR2 FAT1 ZFHX3 CNTN1 PDZD2	1.18e-08	184	148	9	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOK6 PAG1 TSHZ2 RUNX1T1 FAT1 PLXNA4 CCDC68 PDZRN3 UNC80	1.71e-08	192	148	9	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOK6 MYLK TSHZ2 CARMIL1 RUNX1T1 DST VCAN PDZRN3 CNTN1	2.04e-08	196	148	9	1450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	DOK6 MXRA5 MYLK TSHZ2 RUNX1T1 RYR2 DST VCAN PDZRN3	2.14e-08	197	148	9	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DOK6 MYLK TSHZ2 CARMIL1 RUNX1T1 DST VCAN PDZRN3 CNTN1	2.14e-08	197	148	9	11a4c417f035e554431a8f03be13b5eefa3530c0
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	DOK6 MYLK TSHZ2 RUNX1T1 RYR2 DST VCAN PLXNA4 PDZRN3	2.23e-08	198	148	9	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	DOK6 PAG1 MYLK SEPTIN5 RYR2 FAT1 ZFHX3 CNTN1 PDZD2	2.43e-08	200	148	9	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte\|Control_saline / Treatment groups by lineage, cell group, cell type	DOK6 PAG1 MYLK SEPTIN5 ITIH3 RYR2 FAT1 ZFHX3 CNTN1	2.43e-08	200	148	9	cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CACNA1B PAG1 CMYA5 FAT1 PLXNA4 CCDC68 ZFHX3 PDZRN3	5.72e-08	157	148	8	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DUSP6 MUC16 MED13L JMJD1C RYR2 VCAN CNTN5 ZFHX3	2.11e-07	186	148	8	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	DOK6 MYLK TSHZ2 RUNX1T1 RYR2 DST TLN2 PDZRN3	2.20e-07	187	148	8	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AKAP6 MYLK ANK3 ITIH4 RYR2 PLXNA4 RIMS1 PDZRN3	2.29e-07	188	148	8	293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOK6 MYLK TSHZ2 RUNX1T1 DST VCAN PDZRN3 CNTN1	2.58e-07	191	148	8	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYLK SEPTIN5 RUNX1T1 RYR2 FAT1 PLXNA4 ZFHX3 PDZRN3	2.58e-07	191	148	8	08042952431ca1a6fd7dfc13f36eb28643979598
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOK6 MYLK TSHZ2 RUNX1T1 DST VCAN PDZRN3 CNTN1	2.58e-07	191	148	8	806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOK6 MYLK TSHZ2 RUNX1T1 DST VCAN PDZRN3 CNTN1	2.58e-07	191	148	8	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	DOK6 MYLK TSHZ2 RUNX1T1 RYR2 DST TLN2 PDZRN3	2.80e-07	193	148	8	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GTSE1 NDUFA7 RIMS1 USP1 CNTN1 KNL1 SON AURKB	2.91e-07	194	148	8	7a66bd7d4fc9c6db861cedd2487f241e406869d1
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYLK TSHZ2 RUNX1T1 RYR2 DST VCAN PDZRN3 CNTN1	2.91e-07	194	148	8	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	MXRA5 MYLK TSHZ2 RUNX1T1 RYR2 DST VCAN PDZRN3	2.91e-07	194	148	8	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOK6 MYLK TSHZ2 RUNX1T1 RYR2 DST TLN2 PDZRN3	3.14e-07	196	148	8	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	Control-B_memory-3\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PAG1 ANK3 TSHZ2 PIK3R6 IGHG2 IGHG3 IGHG4 NCOA7	3.27e-07	197	148	8	b86385c6c1d52ef4e3d855004d77afab61556978
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOK6 MYLK TSHZ2 RYR2 DST VCAN CCDC68 PDZRN3	3.27e-07	197	148	8	6d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOK6 MYLK TSHZ2 CARMIL1 RUNX1T1 DST VCAN CNTN1	3.27e-07	197	148	8	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	DOK6 MYLK TSHZ2 RUNX1T1 RYR2 DST VCAN PDZRN3	3.27e-07	197	148	8	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOK6 MYLK TSHZ2 RUNX1T1 RYR2 DST VCAN PDZRN3	3.40e-07	198	148	8	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B RYR2 MRTFB CNTN5 RIMS1 UNC79 UNC80 CNTN1	3.40e-07	198	148	8	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DOK6 MYLK TSHZ2 RUNX1T1 DST VCAN PDZRN3 CNTN1	3.40e-07	198	148	8	17dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B DOK6 ANK3 RYR2 RIMS1 UNC79 UNC80 CNTN1	3.40e-07	198	148	8	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOK6 MYLK TSHZ2 RUNX1T1 RYR2 DST VCAN PDZRN3	3.67e-07	200	148	8	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DOK6 PAG1 MYLK SEPTIN5 FAT1 ZFHX3 CNTN1 PDZD2	3.67e-07	200	148	8	d2fcd3bd7c3223875f027eeb48ff621192a5f242
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CACNA1B ANK3 RYR2 MRTFB RIMS1 UNC79 UNC80 CNTN1	3.67e-07	200	148	8	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	AKAP6 DOK6 MYLK SEPTIN5 ITIH3 RYR2 FAT1 ZFHX3	3.67e-07	200	148	8	c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOK6 MYLK TSHZ2 RUNX1T1 RYR2 DST VCAN PDZRN3	3.67e-07	200	148	8	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2\|Control_saline / Treatment groups by lineage, cell group, cell type	DOK6 PAG1 MYLK SEPTIN5 RYR2 FAT1 CNTN1 PDZD2	3.67e-07	200	148	8	bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOK6 MYLK TSHZ2 RUNX1T1 RYR2 DST VCAN PDZRN3	3.67e-07	200	148	8	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOK6 MYLK TSHZ2 RUNX1T1 RYR2 DST VCAN PDZRN3	3.67e-07	200	148	8	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-Plasma_B-Plasma_B-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ERN1 STARD5 IGHG2 IGHG3 IGHG4 DNAJC1 CREB3L2	9.75e-07	157	148	7	63502d0fd5972d71cdbe13bde167592c70acec32
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CALCOCO2 MYLK TSHZ2 PLXNA4 CCDC68 TLN2 PDZRN3	1.42e-06	166	148	7	94636dbc039f794c735960c3425e00bdd5523602
ToppCell	Immune_cells-pro-B\|Immune_cells / Lineage and Cell class	IMPDH1 PAIP2 CECR2 DUSP6 JMJD1C DST PDZD2	1.79e-06	172	148	7	096636f2589fa56d15942aac96641c16fd5fa78d
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 RANBP2 GATA4 CMYA5 JMJD1C RYR2 TASOR	2.09e-06	176	148	7	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	mild_COVID-19_(asymptomatic)-B_memory\|World / disease group, cell group and cell class (v2)	ANK3 NEXMIF PXDC1 IGHG2 IGHG3 IGHG4 SNX2	2.17e-06	177	148	7	057871e211c6508b2a679d391f3cf0ac7ccfc628
ToppCell	10x5'-Liver-Lymphocytic_B_plasma-Plasmablasts\|Liver / Manually curated celltypes from each tissue	GTSE1 IGHG2 IGHG3 IGHG4 RIMS1 KNL1 AURKB	2.17e-06	177	148	7	1d88ae316d65ca5fdc736c9da93885b6b40c32bb
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	AKAP6 MYLK RYR2 VCAN TLN2 ZFHX3 PDZRN3	2.43e-06	180	148	7	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	RANBP2 PAG1 RAPGEF6 ANK3 TSHZ2 JMJD1C TRIM74	2.52e-06	181	148	7	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN RYR2 FAT1 TLN2 UNC79 UNC80 CNTN1	2.81e-06	184	148	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN RYR2 FAT1 TLN2 UNC79 UNC80 CNTN1	2.81e-06	184	148	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	AKAP6 ANK3 CMYA5 RYR2 DST PDZRN3 PDZD2	2.81e-06	184	148	7	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN RYR2 FAT1 TLN2 UNC79 UNC80 CNTN1	2.81e-06	184	148	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ERN1 CARMIL1 IGHG2 IGHG3 IGHG4 DNAJC1 CREB3L2	2.91e-06	185	148	7	3b77bc49cd3740acc025e162a36282ac09e12198
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TSHZ2 RUNX1T1 RYR2 DST VCAN ZFHX3 RIMS1	3.01e-06	186	148	7	7def03dd856b765bd3f493288641981c4f7fd26e
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DOK6 PAG1 MYLK RYR2 FAT1 CCDC68 PDZD2	3.01e-06	186	148	7	888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	AKAP6 MYLK RYR2 DST VCAN PLXNA4 PDZRN3	3.12e-06	187	148	7	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	ILEUM-non-inflamed-(5)_Plasma-(5)_IgG_plasma_cells\|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CARMIL1 ZC3H11A IGHG2 IGHG3 IGHG4 SON CREB3L2	3.23e-06	188	148	7	2156f1bc849ff1cb09ae296d13bedd913ae6b43b
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ERN1 IGHG2 IGHG3 IGHG4 KNL1 CREB3L2 AURKB	3.23e-06	188	148	7	567b08514d9d84cbb40f9b7a679eec304f023428
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AKAP6 SEPTIN5 CARMIL1 ITIH3 RYR2 FAT1 ZFHX3	3.35e-06	189	148	7	975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	AKAP6 MYLK CMYA5 RUNX1T1 DST PDZRN3 CNTN1	3.35e-06	189	148	7	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	metastatic_Lymph_Node-B_lymphocytes-MALT_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	SELPLG ERN1 IGHG2 IGHG3 IGHG4 DNAJC1 CREB3L2	3.47e-06	190	148	7	5ec49cc7692053c1a525ca9137c996ccd2794e1c
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	DOK6 MYLK RUNX1T1 RYR2 DST VCAN PDZRN3	3.47e-06	190	148	7	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AKAP6 SEPTIN5 ITIH3 RYR2 FAT1 ZFHX3 PDZRN3	3.47e-06	190	148	7	73d94fbae92029745989a8712eed8b99fd84c193
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	AKAP6 ANK3 CMYA5 RYR2 DST PDZRN3 PDZD2	3.47e-06	190	148	7	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	AKAP6 ANK3 CMYA5 RYR2 DST PDZRN3 PDZD2	3.59e-06	191	148	7	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	(5)_Plasma-(5)_Plasma_IgG\|(5)_Plasma / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ERN1 IGHG2 IGHG3 IGHG4 IQCG	3.67e-06	70	148	5	bfe020c111a27337ed4dc6ee59b74bc36b03eb49
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATAD5 GTSE1 IGHG2 IGHG3 IGHG4 DNAJC1 AURKB	3.72e-06	192	148	7	b9c606547c303a099a653169923a44c20816a604
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	AKAP6 ANK3 TSHZ2 TRIM73 MRTFB ATP2C2 CFAP57	3.85e-06	193	148	7	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	ILEUM-inflamed-(8)_Smooth_muscle_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MXRA5 MYLK RUNX1T1 FAT1 DST PDZRN3 CNTN1	3.85e-06	193	148	7	084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCell	metastatic_Brain-B_lymphocytes-MALT_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	ERN1 IGHG2 IGHG3 IGHG4 DNAJC1 CREB3L2 AURKB	3.85e-06	193	148	7	d05535eaabb6b4069b72b23d852888d4191407fd
ToppCell	droplet-Heart-HEART-1m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPT NEXMIF LBP CASKIN2 ECSCR CFAP57 SEC14L4	3.85e-06	193	148	7	d0a5f212f8e8a13dbbe3e41df92548ef82eef70b
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	DOK6 MYLK TSHZ2 RUNX1T1 RYR2 DST PDZRN3	3.85e-06	193	148	7	acad568621ed677031797b8c2e34dafea798d681
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOK6 MYLK TSHZ2 RUNX1T1 VCAN PDZRN3 CNTN1	3.98e-06	194	148	7	a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	AKAP6 ANK3 GATA4 CMYA5 RYR2 DST PDZRN3	4.12e-06	195	148	7	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	facs-Brain_Myeloid-Hippocampus\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG KAT6A CHGA USP8 DST ECSCR ZFHX3	4.12e-06	195	148	7	a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MYLK TSHZ2 CARMIL1 RUNX1T1 DST VCAN CCDC68	4.12e-06	195	148	7	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B RYR2 MRTFB RIMS1 UNC79 UNC80 CNTN1	4.26e-06	196	148	7	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	COPD-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	PAG1 RAPGEF6 ANK3 ERN1 TSHZ2 JMJD1C RYR2	4.26e-06	196	148	7	c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCell	PCW_13-14-Mesenchymal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOK6 MYLK TSHZ2 RUNX1T1 DST VCAN PDZRN3	4.40e-06	197	148	7	73a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	MYLK ANK3 TSHZ2 RUNX1T1 RYR2 VCAN PDZRN3	4.40e-06	197	148	7	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B RYR2 MRTFB RIMS1 UNC79 UNC80 CNTN1	4.55e-06	198	148	7	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYLK TSHZ2 RUNX1T1 RYR2 DST VCAN PDZRN3	4.55e-06	198	148	7	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B RYR2 MRTFB RIMS1 UNC79 UNC80 CNTN1	4.55e-06	198	148	7	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B RYR2 MRTFB RIMS1 UNC79 UNC80 CNTN1	4.55e-06	198	148	7	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-pre_pro_B_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PAG1 PAIP2 GTSE1 USP1 SNX2 KNL1 AURKB	4.55e-06	198	148	7	8aa4149d2c1cec73cfd654db093252ec8ec5ef68
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYLK TSHZ2 CMYA5 FAT1 DST PLXNA4 CNTN1	4.70e-06	199	148	7	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CMYA5 VCAN ATP2C2 UNC79 UNC80 CNTN1 PDZD2	4.70e-06	199	148	7	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	Influenza-Influenza_Severe-Lymphocyte-B-B_memory\|Influenza_Severe / Disease, condition lineage and cell class	IMPDH2 TSHZ2 PXDC1 IGHG2 IGHG3 IGHG4 CLNK	4.70e-06	199	148	7	bf0285f68c9cb1417fc070abc3cb224d07407e0e
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	DOK6 MYLK TSHZ2 RUNX1T1 RYR2 DST PDZRN3	4.70e-06	199	148	7	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	PCW_10-12-Mesenchymal\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DOK6 MYLK TSHZ2 RUNX1T1 DST VCAN PDZRN3	4.70e-06	199	148	7	a09292de4c4447b8eee55d401808e43b817321cc
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSHZ2 CYP24A1 CMYA5 TRIM29 FAT1 DST NCOA7	4.70e-06	199	148	7	c88a28a73f54dc571f2ff1e4b55073f83cbead2c
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DOK6 MYLK SEPTIN5 ITIH3 FAT1 ZFHX3 CNTN1	4.86e-06	200	148	7	b5b5a32925f225610fe25a021a742d6397162863
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	DOK6 PAG1 MYLK RYR2 FAT1 CCDC68 PDZD2	4.86e-06	200	148	7	0c648941447c738caf62f2d71e296d6cca492c8b
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	AKAP6 MYLK SEPTIN5 ITIH3 RYR2 FAT1 ZFHX3	4.86e-06	200	148	7	9169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell	COVID-19-COVID-19_Severe\|COVID-19 / Disease, condition lineage and cell class	MYLK SLC25A37 GAS2L1 IGHG2 IGHG3 IGHG4 MTARC1	4.86e-06	200	148	7	3ec89071f002bb66d46146bf4804f91e6f09a36f
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DOK6 PAG1 MYLK RYR2 FAT1 CCDC68 PDZD2	4.86e-06	200	148	7	522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DOK6 PAG1 MYLK SEPTIN5 RYR2 FAT1 ZFHX3	4.86e-06	200	148	7	786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	AKAP6 MYLK SEPTIN5 ITIH3 RYR2 FAT1 ZFHX3	4.86e-06	200	148	7	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DOK6 PAG1 MYLK RYR2 FAT1 CCDC68 PDZD2	4.86e-06	200	148	7	94f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3\|Control_saline / Treatment groups by lineage, cell group, cell type	AKAP6 MYLK SEPTIN5 ITIH3 RYR2 FAT1 ZFHX3	4.86e-06	200	148	7	b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_only / Treatment groups by lineage, cell group, cell type	AKAP6 MYLK SEPTIN5 ITIH3 RYR2 FAT1 ZFHX3	4.86e-06	200	148	7	7c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	MYLK TSHZ2 FAT1 VCAN PLXNA4 RIMS1 PDZRN3	4.86e-06	200	148	7	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	PAG1 KAT6A MED13L JMJD1C VCAN SPEN	6.06e-06	135	148	6	b128596653a5e3b64ed7f657bbfeda35438e2e48
Drug	0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A	TRIM29 STARD5 GAS2L1 R3HCC1L CASKIN2 ARHGEF1 TLN2 ZFHX3 PIGO	4.40e-06	194	145	9	4331_DN
Drug	temacrazine	IMPDH1 IMPDH2 ITIH4	2.07e-05	9	145	3	CID000472178
Drug	amdoxovir	IMPDH1 IMPDH2 ITIH4 PKLR	2.87e-05	28	145	4	CID000124088
Drug	Tranylcypromine hydrochloride [1986-47-6]; Down 200; 23.6uM; MCF7; HT_HG-U133A	SRCAP CASKIN2 ARHGEF1 TLN2 PIGO TOP3A CNTN1 IQCG	3.67e-05	195	145	8	2264_DN
Drug	Diethylcarbamazine citrate [1642-54-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A	KAT6A GATA4 SRCAP RYR2 RNF123 R3HCC1L AQR TOP3A	3.95e-05	197	145	8	7425_DN
Drug	Flucloxacillin sodium [1847-24-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A	IMPDH1 DDX52 GAS2L1 TOX4 R3HCC1L CASKIN2 TLN2 TOP3A	3.95e-05	197	145	8	5527_DN
Drug	hydroxymethylphosphonate	IMPDH1 IMPDH2	4.03e-05	2	145	2	CID000075795
Drug	6-Chloropurine Riboside, 5'-Monophosphate	IMPDH1 IMPDH2	4.03e-05	2	145	2	DB03948
Drug	Mycophenolate mofetil	IMPDH1 IMPDH2	4.03e-05	2	145	2	DB00688
Drug	purinogen	IMPDH1 IMPDH2	4.03e-05	2	145	2	CID003081226
Drug	AC1L9X6T	IMPDH1 IMPDH2	4.03e-05	2	145	2	CID000477594
Drug	Mycophenolic acid	IMPDH1 IMPDH2	4.03e-05	2	145	2	DB01024
Drug	Trimethobenzamide hydrochloride [554-92-7]; Up 200; 9.4uM; PC3; HG-U133A	MYLK ERN1 ATAD5 DUSP6 CEACAM3 TRIM29 TLN2 PIGO	4.24e-05	199	145	8	1920_UP
Drug	Repaglinide [135062-02-1]; Down 200; 8.8uM; PC3; HT_HG-U133A	RAP1GAP MYLK IMPDH1 EP400 DDX52 SLC25A37 ATP2C2 CCDC68	4.39e-05	200	145	8	5862_DN
Disease	Adenoid Cystic Carcinoma	KAT6A SRCAP JMJD1C FAT1 VCAN SON	1.03e-05	100	145	6	C0010606
Disease	attention deficit hyperactivity disorder	AKAP6 RANBP2 TSHZ2 CYP24A1 DUSP6 RUNX1T1 CLYBL ATP2C2 ZFHX3 MAP3K7	1.07e-05	354	145	10	EFO_0003888
Disease	immunoglobulin G measurement	IGHG2 IGHG4	2.40e-05	2	145	2	EFO_0020465
Disease	Salivary Gland Neoplasms	FAT1 VCAN SPEN SON	8.47e-05	47	145	4	C0036095
Disease	Neurodevelopmental Disorders	NEXMIF MED13L SRCAP CDKL5 RIMS1	9.82e-05	93	145	5	C1535926
Disease	PR interval	AKAP6 MARK3 CARMIL1 PSMA5 RAP1GAP2 CUL9 RYR2 FAT1 CASKIN2 PDZRN3	1.77e-04	495	145	10	EFO_0004462
Disease	Colorectal Carcinoma	AKAP6 CALCOCO2 TFEC PAIP2 GATA4 RUNX1T1 CDKL5 FAT1 CCNB3 ARHGEF1 PIGO CNTN1	1.90e-04	702	145	12	C0009402
Disease	granulocyte percentage of myeloid white cells	UBR2 ATAD5 MARK3 MED13L JMJD1C USP8 DNAJC1	3.75e-04	268	145	7	EFO_0007997
Disease	bipolar disorder, body mass index	TSHZ2 RUNX1T1 CFAP57 PDZD2	4.44e-04	72	145	4	EFO_0004340, MONDO_0004985
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	AKAP6 TSHZ2 DUSP6 RUNX1T1 RYR2 CLYBL PLXNA4 ZFHX3 DNAJC1 MAP3K7 UNC79 PDZRN3	6.20e-04	801	145	12	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	ascending aortic diameter	ATAD5 MED13L JMJD1C SLC25A37 RYR2	6.55e-04	140	145	5	EFO_0021787
Disease	diet measurement	SLC4A8 ANK3 CARMIL1 GATA4 RUNX1T1 JMJD1C DST MUC17 CNTN5 CCDC68 ZFHX3 RIMS1 DNAJC1 DAGLA	6.87e-04	1049	145	14	EFO_0008111
Disease	dipeptidase 2 measurement	CENPT ITIH4	1.05e-03	10	145	2	EFO_0801528
Disease	response to methotrexate, serum alanine aminotransferase measurement	RAP1GAP2 ATP2C2 PDZD2	1.24e-03	43	145	3	EFO_0004735, GO_0031427
Disease	interleukin-6 measurement, response to stimulus	CARMIL1 MUC16	1.28e-03	11	145	2	EFO_0004810, GO_0050896
Disease	Cleft palate, tobacco smoke exposure measurement, cleft lip, parental genotype effect measurement	ANK3 RUNX1T1	1.28e-03	11	145	2	EFO_0003959, EFO_0005939, EFO_0009115, HP_0000175
Disease	esophagus squamous cell carcinoma (is_implicated_in)	CYP24A1 FAT1 SPEN	1.42e-03	45	145	3	DOID:3748 (is_implicated_in)
Disease	Malignant neoplasm of salivary gland	FAT1 VCAN SON	1.42e-03	45	145	3	C0220636
Disease	alkaline phosphatase measurement	CALCOCO2 RAP1GAP SLC4A8 ERN1 CARMIL1 CYP24A1 GATA4 FBXW4 JMJD1C ITIH3 ITIH4 MTARC1 CREB3L2	1.54e-03	1015	145	13	EFO_0004533
Disease	blood phosphate measurement	RAP1GAP CYP24A1 USP8 ZFHX3 KNL1	1.73e-03	174	145	5	EFO_0010972
Disease	smoking status measurement	SLC4A8 TSHZ2 RUNX1T1 RYR2 CLYBL CNTN5 PLXNA4 CCDC68 ZFHX3 RIMS1 DNAJC1 MAP3K7 UNC79 CNTN1	1.78e-03	1160	145	14	EFO_0006527
Disease	femoral neck bone geometry	HK2 PPP6R3	2.10e-03	14	145	2	EFO_0004511
Disease	pathological myopia	PAG1 GATA4 CNTN5 CLNK	2.23e-03	111	145	4	EFO_0004207
Disease	atrial fibrillation	AKAP6 GATA4 CHGA JMJD1C CNTN5 ZFHX3 SPEN	2.46e-03	371	145	7	EFO_0000275
Disease	gout	CARMIL1 RUNX1T1 FAT1 DST CLNK	2.89e-03	196	145	5	EFO_0004274
Disease	Antihistamine use measurement	WDR36 CLYBL	3.11e-03	17	145	2	EFO_0009943
Disease	body fat distribution	ZC3H11B SLC25A37 VCAN PKLR CREB3L2	3.29e-03	202	145	5	EFO_0004341
Disease	attention deficit hyperactivity disorder, Cannabis use	DUSP6 RUNX1T1	3.48e-03	18	145	2	EFO_0003888, EFO_0007585
Disease	APOE carrier status, dementia	TSHZ2 CEACAM3 CLYBL	3.56e-03	62	145	3	EFO_0007659, MONDO_0001627
Disease	body weight	AKAP6 CACNA1B ATAD5 NEXMIF DUSP6 GATA4 RUNX1T1 SLC25A37 TOX4 TLN2 ZFHX3 MAP3K7 UNC79 PDZD2	3.78e-03	1261	145	14	EFO_0004338
Disease	Brugada syndrome	GATA4 NCOA7	3.88e-03	19	145	2	MONDO_0015263
Disease	Cannabis use, age at onset	RYR2 ATP2C2	3.88e-03	19	145	2	EFO_0004847, EFO_0007585
Disease	response to vaccine, cytokine measurement	ITIH3 ITIH4 CNTN5 DAGLA	4.05e-03	131	145	4	EFO_0004645, EFO_0004873
Disease	retinal vasculature measurement	PIWIL2 MED13L RB1CC1 MUC17 DNAJC1 ELP4 KNL1 PDZD2	4.15e-03	517	145	8	EFO_0010554
Disease	breast carcinoma (is_marker_for)	CYP24A1 MDC1 ZFHX3	4.24e-03	66	145	3	DOID:3459 (is_marker_for)
Disease	exercise test	RYR2 CNTN5	4.30e-03	20	145	2	EFO_0004328
Disease	chronotype measurement	CALCOCO2 EPC2 TFEC ANK3 MED13L RUNX1T1 RNF123 CNTN5 PLXNA4 RIMS1 CLNK	4.31e-03	882	145	11	EFO_0008328
Disease	serum IgG glycosylation measurement	SEPTIN5 CYP24A1 LBP RYR2 IGHG2 IGHG4 MDC1 CNTN1	4.44e-03	523	145	8	EFO_0005193
Disease	mean platelet volume	ZAN ATAD5 CARMIL1 CYP24A1 GATA4 SRCAP JMJD1C SLC25A37 TOX4 CCDC68 TASOR SNX2	4.61e-03	1020	145	12	EFO_0004584
Disease	body surface area	ZC3H11B MED13L SLC25A37 NCOA7 ZFHX3 C12orf60 TASOR UNC79 PPP6R3	4.63e-03	643	145	9	EFO_0022196
Disease	platelet measurement	DOK6 SEPTIN5 CARMIL1 JMJD1C TASOR SNX2	4.76e-03	315	145	6	EFO_0005036

Protein segments in the cluster

Peptide	Gene	Start	Entry
SESPIRMKFTRISTP	ATAD5	651	Q96QE3
MIKKPLERESISTTP	DDX52	556	Q9Y2R4
PRKLMEEISTSAAPA	EP400	1436	Q96L91
SMDRVPKVTPSSAIS	EPC2	766	Q52LR7
SRTLTPTPDGKTMLR	ARHGEF1	691	Q92888
SLSKEPQMVSDRTTP	VCAN	366	P13611
KEFPVTETPLVTARM	VCAN	511	P13611
ISPRTPASKIASEMA	AKAP4	261	Q5JQC9
VRKTSMAVPSLTETP	ADGRG4	1096	Q8IZF6
MDSSTEAPPISIKSR	CARMIL2	1251	Q6F5E8
TPREIMSPAKETSEK	ANKRD30A	391	Q9BXX3
SVLKSVPLSEPVTMD	AQR	231	O60306
MTTVTVTTEIPPRDK	CCDC68	1	Q9H2F9
PVTDASPMKRSISTL	CACNA1B	2011	Q00975
NSRPIKTATTLPDDM	DNAJC1	396	Q96KC8
LTSPTRMDAVAAKVP	CECR2	1276	Q9BXF3
KEMPEDRASTPRTTT	ATP2C2	826	O75185
EPMSFRKNPTTEETV	CCNB3	566	Q8WWL7
SRVLPSSLMLPKVES	CLYBL	126	Q8N0X4
TPSRMIRTNEAVPKT	CNTN5	761	O94779
MASTITKIPSPLITE	IQCG	111	Q9H095
TPLTSMVVTKPDDQE	ITIH4	586	Q14624
PDRESSSMETSIEPK	R3HCC1L	546	Q7Z5L2
PSVSSETMDKPVDLS	RANBP2	2806	P49792
RTKMFTPPSESQLVD	PDZRN3	341	Q9UPQ7
MKDPSRSSTSPSIIN	PAIP2	1	Q9BPZ3
EDPKVMITTSRDPSS	IMP4	81	Q96G21
RSTELVLSPDMPRTT	RB1CC1	236	Q8TDY2
DKGSPPMSEITSVRI	FAT1	1641	Q14517
SSEVPLPMAITSRSD	MUC16	2141	Q8WXI7
VTSVPTPTLAKITDM	MUC16	6251	Q8WXI7
RIEMESTSTLTPTPR	MUC16	8991	Q8WXI7
PLTRKESTDMAITPK	MUC16	9356	Q8WXI7
KMPSGATPEVSRTEV	MUC16	9606	Q8WXI7
LEPVISVRSRPTSMT	C22orf46	206	C9J442
DMIPPDSNIRLTTKS	LBP	306	P18428
SLSVDPSRVDSMPLT	MYLK	16	Q15746
SKRSQMSTPTLEEEP	MED13L	391	Q71F56
SKTLRSSTVRAMPVP	MDC1	1681	Q14676
TTVDPDTGVMSRKEP	MTARC1	276	Q5VT66
STMPDSPVDVKTQSR	RUNX1T1	36	Q06455
VSPMTNSSELKPESR	DST	3206	Q03001
VSETEPSRDMLSTAP	CFAP57	1176	Q96MR6
LKTPLVSSPMDTVTE	IMPDH2	61	P12268
IVRPSSSTKTDSMPA	JMJD1C	1306	Q15652
VKMLPTFVRSTPDGT	HK2	61	P52789
SRTPMITPDLESGVK	PLXNA4	1636	Q9HCM2
RPTSDRSPTQDKMVS	OR2M3	261	Q8NG83
RPTSDRSPMQDKLVS	OR2M5	261	A3KFT3
PARSPDSKIQMVSSS	PDZD2	1826	O15018
VESLPPTSEGKRMSA	MAP3K7	376	O43318
SPISKMRPVTASITT	MRTFB	921	Q9ULH7
SMITKPRPTRAETSD	PKLR	376	P30613
ECKTVSPDEITTRPM	KNL1	951	Q8NG31
SPDEITTRPMDKTVV	KNL1	956	Q8NG31
EKRITSPLMEPSSIE	PSMA5	51	P28066
REMTLKIPETSSLGT	PCDHB15	136	Q9Y5E8
DVPTISRMTPEDLTA	CASKIN2	516	Q8WXE0
SSEPRKNSAMRTEPT	GTSE1	546	Q9NYZ3
LKTPLISSPMDTVTE	IMPDH1	61	P20839
STPAATTLPVMIKTE	PROSER1	596	Q86XN7
SQKMERPSISVISPT	RIMS1	716	Q86UR5
RESVPPSIIMSSQKA	NDUFA7	61	O95182
EVSLTQKTDPSVRPM	OCIAD1	211	Q9NX40
SEKKPEVMAPVSSTR	KAT6A	831	Q92794
SSSEEMRPIKTEPGL	GATA4	356	P43694
LKESMRLTPSVPFTT	CYP24A1	381	Q07973
LTEPMTLSKSISLPR	DOK6	251	Q6PKX4
ETPLSASTKMLERFP	ERN1	366	O75460
SPSEVRVETSAMVDP	DBF4B	111	Q8NFT6
SRPEMTPVSLRSTKE	GAS2L1	316	Q99501
VTPDTPATMFLRTTK	CMYA5	381	Q8N3K9
TAPESSILMPESVVK	CENPT	96	Q96BT3
RKVLEPMPSTAEIST	CNTN1	276	Q12860
SLSMREDATILPSPT	ECSCR	101	Q19T08
ELIDKLEVVTMPSPS	MTFMT	76	Q96DP5
MEETIKDPPTSAVLL	CALCOCO2	1	Q13137
MPPASMRTSTSEKEL	ANK3	2081	Q12955
PTTAKLTIESMPLSV	CEACAM3	31	P40198
TRLGTDLMTSVPVKE	FBXW4	81	P57775
MSTRTPLPTVNERDT	MARK3	1	P27448
AAKVMVSPTEVDLTP	DAGLA	676	Q9Y4D2
TEAEPTKTRTETPMA	CUL9	621	Q8IWT3
SRSKSERPPTILMTE	CARMIL1	1076	Q5VZK9
PKDTLMISRTPEVTC	IGHG2	126	P01859
KPKDTLMISRTPEVT	IGHG3	176	P01860
KPKDTLMISRTPEVT	IGHG4	126	P01861
PPDLSDTVSRSSKMD	ELP4	386	Q96EB1
EQLPPEMTVARSSVK	CDKL5	651	O76039
RPVPFASEMAISKTV	DUSP6	6	Q16828
EETLQSLKAMRPSPT	SEC14L4	391	Q9UDX3
IVPMTEETKSITLFP	RYR2	1726	Q92736
FLSEKSVSMEVEPSP	CREB3L2	56	Q70SY1
LRSMPVSTKPLASSE	MUC17	2576	Q685J3
PSATEALSMEPTTKR	SELPLG	266	Q14242
PRIESKSMSAPVIFD	SNX2	111	O60749
IFSESRKPTVSIMEP	TRIM29	131	Q14134
PSFQSPVKISEIMRS	PXDC1	146	Q5TGL8
SEKRSAKSSEMSPVP	RAPGEF6	1146	Q8TEU7
AATPIIMSRSPTDAK	RAP1GAP2	691	Q684P5
TSKLTQDSRMESPIP	SEPTIN5	316	Q99719
TPPETKPREDVSMTS	SNAP47	231	Q5SQN1
PRRSMVASKIPSATD	LRRC27	386	Q9C0I9
MTSDSRPIVPLEKST	NCOA7	341	Q8NI08
TPPMKRDSQEESSIS	SSMEM1	221	Q8WWF3
ETVSKTPLKREMLPS	PIWIL2	81	Q8TC59
TPLTSMVVTKPEDNE	ITIH3	596	Q06033
TPSLSPQITRCESMK	NEXMIF	1076	Q5QGS0
MVPITSLPSTLRTLE	FBXL12	116	Q9NXK8
GISRSKTPVDDPMSL	ID2	21	Q02363
KLAEMPPSLDTSRTV	PIK3R6	501	Q5UE93
VDSVKTRMQSLSPDP	SLC25A37	66	Q9NYZ2
SSPEMPTTKNRAETA	RAP1GAP	541	P47736
MSSSVKTPALEELVP	SLC35E2A	1	P0CK97
PSEINISDEMPKTTV	SLC4A8	1061	Q2Y0W8
PKETIPSMEDSDVSL	IMPG2	541	Q9BZV3
TMVSRLPVSKDEPDT	SRCAP	1836	Q6ZRS2
IPPESAVDTMLTARS	PAG1	136	Q9NWQ8
DMAREPVEETTKSPS	TASOR	1181	Q9UK61
DLKPEMSRSTPSLVD	AKAP6	416	Q13023
MDTPLPLDTRTSISI	CLNK	106	Q7Z7G1
IVEVISDTLSKPSPM	CHGA	36	P10645
ERTRSPPGSSKTTMI	C12orf60	171	Q5U649
KEPVTPSALVLMSRS	AURKB	31	Q96GD4
PVTPVSTVCSRMKEE	TRIM74	121	Q86UV6
SRKPEAMDEPVLTSS	UNC80	3141	Q8N2C7
KRSSELLDPTTPMRT	TCEANC	161	Q8N8B7
PKITSVISRMPVSID	SPEN	2616	Q96T58
DSRGPRTTEPSTKSM	SPATC1	401	Q76KD6
SLMTPRRPLSTSEKV	RNF123	691	Q5XPI4
DSPQISITDIKMTSP	TKTL2	296	Q9H0I9
PSPQLRSVMKVESSE	ZC3H11A	131	O75152
RSVMKVESSENVPSP	ZC3H11A	136	O75152
TSTPSAAMKLISPRD	STARD5	101	Q9NSY2
MKMESTVSITRTPPR	nan	301	Q9UF83
EKENSRTETTMSPPR	ZNF646	601	O15015
MSSSVKTPALEELVP	SLC35E2B	1	P0CK96
VMDKPVLSPASTRSA	TSHZ2	736	Q9NRE2
DPMATVVEVRSKPKS	TOP3A	306	Q13472
RSVMKVESSENVPSP	ZC3H11B	136	A0A1B0GTU1
VPEKTSSPEESIRMT	TLN2	2166	Q9Y4G6
PVTPVSTVCSRMKEE	TRIM73	121	Q86UV7
DPPTTTMQRLKALTT	PIGO	126	Q8TEQ8
CPSSLPMKREITETD	TFEC	116	O14948
STPKTMLSRLVISPT	WEE2	111	P0C1S8
KMRESSPTSPVAETE	UBR2	1001	Q8IWV8
LRSNSPVEMETSTEP	PPP6R3	736	Q5H9R7
TKPVVFSPTLMLTDE	USP8	446	P40818
LKSVESTSPEPSKIM	SON	276	P18583
LPSEPVDISTAMSER	SON	2216	P18583
LKMQTTLVPPTVESS	TOX4	501	O94842
SSEISPEPKTEMKTL	USP1	471	O94782
PSSLERTPTKMTTSQ	YEATS2	401	Q9ULM3
SPVSKTMELSPRTLL	ZFHX3	2786	Q15911
PSTKGLSTLEMPRES	UNC79	1871	Q9P2D8
LSTLEMPRESSSAPT	UNC79	1876	Q9P2D8
TMSVRLPPITKFAAE	WDR36	436	Q8NI36
PTISMEETIISTEKP	ZAN	696	Q9Y493
EETTISTEKPSIPME	ZAN	806	Q9Y493
SIPMEKPTLPTEETT	ZAN	816	Q9Y493
TTISTEKLTIPMEKP	ZAN	836	Q9Y493
EKLTIPMEKPTISTE	ZAN	841	Q9Y493
ARMKEPASSSPSTIL	MXRA5	1486	Q9NR99