Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionSMAD binding

USP9Y FOXA2 FOS

1.66e-0486253GO:0046332
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

BTD NDST2

4.59e-0381252GO:0016811
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

FOXN1 FOXA2 FOS ZNF292

4.85e-03560254GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

FOXN1 FOXA2 FOS ZNF292

5.03e-03566254GO:0001216
GeneOntologyBiologicalProcessheparin biosynthetic process

GLCE NDST2

7.71e-0511252GO:0030210
GeneOntologyBiologicalProcessmodulation by host of symbiont process

CDK9 PIK3C2G SAP30BP

1.78e-0491253GO:0051851
GeneOntologyBiologicalProcessheparin metabolic process

GLCE NDST2

1.90e-0417252GO:0030202
DomainTF_fork_head_CS_2

FOXN1 FOXA2

1.72e-0346252IPR030456
DomainTF_fork_head_CS_1

FOXN1 FOXA2

1.79e-0347252IPR018122
DomainFORK_HEAD_3

FOXN1 FOXA2

1.95e-0349252PS50039
DomainFH

FOXN1 FOXA2

1.95e-0349252SM00339
DomainFORK_HEAD_1

FOXN1 FOXA2

1.95e-0349252PS00657
DomainFORK_HEAD_2

FOXN1 FOXA2

1.95e-0349252PS00658
DomainForkhead

FOXN1 FOXA2

1.95e-0349252PF00250
DomainFork_head_dom

FOXN1 FOXA2

1.95e-0349252IPR001766
DomainKinase-like_dom

CDK9 LMTK2 PHKG1 PIK3C2G

5.47e-03542254IPR011009
DomainProtein_kinase_ATP_BS

CDK9 LMTK2 PHKG1

1.37e-02379253IPR017441
PathwayREACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM

GLCE VCAN NDST2

4.90e-0557183M692
PathwayKEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_BIOSYNTHESIS

GLCE NDST2

8.41e-0511182M47921
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

PHKG1 GLCE VCAN NDST2

4.16e-04288184M16864
PathwayKEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE

GLCE NDST2

4.91e-0426182M7330
PathwayREACTOME_GLYCOSAMINOGLYCAN_METABOLISM

GLCE VCAN NDST2

5.16e-04126183M695
Pubmed

miR-590-3p Promotes Ovarian Cancer Growth and Metastasis via a Novel FOXA2-Versican Pathway.

FOXA2 VCAN

1.49e-06325229748371
Pubmed

Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate.

GLCE VCAN NDST2

2.51e-063725332201365
Pubmed

Heparan sulfate structure in mice with genetically modified heparan sulfate production.

GLCE NDST2

2.97e-06425215292174
Pubmed

Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues.

FOXN1 FOXA2

4.95e-0652529032290
Pubmed

Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development.

GLCE NDST2

4.95e-06525217289920
Pubmed

Deubiquitinase OTUD3 regulates metabolism homeostasis in response to nutritional stresses.

FOXN1 FOXA2

1.78e-05925235675826
Pubmed

Defective liver formation and liver cell apoptosis in mice lacking the stress signaling kinase SEK1/MKK4.

FOXA2 FOS

1.78e-0592529876179
Pubmed

A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships.

GLCE NDST2

1.78e-05925230377379
Pubmed

Tissue-specific roles for sonic hedgehog signaling in establishing thymus and parathyroid organ fate.

FOXN1 FOXA2

3.85e-051325227633995
Pubmed

Developmental changes in cellular and extracellular structural macromolecules in the secondary palate and in the nasal cavity of the mouse.

FOXA2 VCAN

4.49e-051425220572855
Pubmed

Serum response factor is essential for mesoderm formation during mouse embryogenesis.

FOXA2 FOS

5.92e-05162529799237
Pubmed

Hedgehog regulation of epithelial cell state and morphogenesis in the larynx.

FOXN1 FOXA2

6.70e-051725236398878
Pubmed

Multiple roles for HOXA3 in regulating thymus and parathyroid differentiation and morphogenesis in mouse.

FOXN1 FOXA2

8.42e-051925225249461
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

CDK9 LIG3 THYN1 USP9Y VCAN ZNF292

9.53e-05108225638697112
Pubmed

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.

STRN4 LMTK2 FHIP1A

9.84e-0512525329467281
Pubmed

Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.

FOXA2 VCAN

1.24e-042325230814516
Pubmed

Loss of Hs3st3a1 or Hs3st3b1 enzymes alters heparan sulfate to reduce epithelial morphogenesis and adult salivary gland function.

GLCE NDST2

1.36e-042425234653670
Pubmed

Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development.

FOXN1 FOXA2

1.60e-042625232467237
Pubmed

The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1.

LIG3 FOS

1.99e-042925219633665
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

STRN4 CDK9 USP9Y SAP30BP

2.41e-0443225423455922
Pubmed

Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome.

FOXA2 FOS

3.25e-043725222001906
Pubmed

Implications of Nef: host cell interactions in viral persistence and progression to AIDS.

CDK9 FOS

4.00e-044125220012528
Pubmed

A conserved acetylation switch enables pharmacological control of tubby-like protein stability.

STRN4 CDK9 ZNF292

5.39e-0422325333187986
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

STRN4 CDK9 LMTK2 LIG3

7.01e-0457325428330616
GeneFamilyForkhead boxes

FOXN1 FOXA2

6.49e-0443162508
CoexpressionJOHANSSON_BRAIN_CANCER_EARLY_VS_LATE_UP

TACC3 FOS

1.83e-057252M1239
CoexpressionJOHANSSON_BRAIN_CANCER_EARLY_VS_LATE_UP

TACC3 FOS

1.83e-057252MM1117
CoexpressionHALLMARK_HYPOXIA

PHKG1 FOS ZNF292 NDST2

3.67e-05200254M5891
CoexpressionTURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_DN

LIG3 TACC3 VCAN

4.75e-0574253M13547
CoexpressionLAKE_ADULT_KIDNEY_C17_COLLECTING_SYSTEM_PCS_STRESSED_DISSOC_SUBSET

PIK3C2G FHIP1A FOS ZNF292

7.45e-05240254M39236
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#4_top-relative-expression-ranked_500

FOXA2 FOS ZNF292

3.44e-0554253gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_500_k4
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic-Mast|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOS CA1 NDST2

9.58e-05160253ca212634cf1875238071d1800ecdf34979a553fb
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOS CA1 NDST2

9.58e-051602535d22c86deead516444349d495998e04586be4396
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PIK3C2G FHIP1A VCAN

1.07e-04166253a907d39ca5cf023de633fe5f2b28759b7af4eebc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PIK3C2G FHIP1A VCAN

1.13e-041692531c9e54e7b14eb99996590fb93b257cf881a9f184
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PIK3C2G FHIP1A GLCE

1.19e-04172253cecfe5cf20f317ea01b4604789e07a14481c4cd6
ToppCellControl-CD4+_T_activated|Control / Disease group and Cell class

FHIP1A FOS VCAN

1.23e-041742532b683e81b315ad22555314433aed5681feb48da8
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PIK3C2G FHIP1A VCAN

1.23e-04174253912a9e892b29d945666fc37c986009c97c668ac8
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

USP9Y FHIP1A CA1

1.27e-041762533fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PIK3C2G FHIP1A VCAN

1.29e-0417725362f180d5a487b449f715de49ee1e1e11c4e0cf4d
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRMT8 FOXA2 PIK3C2G

1.34e-04179253ca70a5518c5a5392e088c103e0cb44aa084f5332
ToppCellNS-critical-d_0-4-Myeloid-Mast_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LIG3 BTD NDST2

1.34e-041792536153e7a0eeae83e7d88f1a20093bf2113e8d66b1
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRMT8 FOXA2 PIK3C2G

1.34e-04179253c451b074b04eb5d6c575c6abaedda579c6744bbf
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXN1 FOXA2 FHIP1A

1.36e-04180253d553aba594f5304f1c09ff9c6d49b64cd7ee7850
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PHKG1 VCAN NDST2

1.38e-04181253a8d4b2340d99734bf9379b467fb481c598b9b4fb
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PRMT8 PIK3C2G FHIP1A

1.57e-04189253c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCellControl-Myeloid-MoAM3,_VCAN|Control / Condition, Lineage and Cell class

KLHL30 FOS VCAN

1.62e-0419125376c2fbc62855a65600cd6b8dd1e2d2c3d7415921
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRMT8 FHIP1A CA1

1.62e-0419125323776c7302cead3881b39127398f3b3e0d27885e
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_3|Classical_Monocyte / Disease condition and Cell class

NDUFB9 FOS VCAN

1.74e-041962537c3a99f0893c43d8c7980b560503844573d3b03c
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SCUBE1|Neuronal / cells hierarchy compared to all cells using T-Statistic

PIK3C2G FHIP1A VCAN

1.85e-04200253012dd2180f6f596d6e55e864be2e62b53c15edb2
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SLC17A7_IL15--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

PIK3C2G FHIP1A VCAN

1.85e-042002539103e6f72a04f66f2b7069b0d71a719e9b10026b
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SCUBE1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PIK3C2G FHIP1A VCAN

1.85e-0420025306f949c81eecba00203f0716d0c5854724871184
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate|2m / Sample Type, Dataset, Time_group, and Cell type.

FOXA2 VCAN ZNF292

1.85e-042002532a635694844ddabcd98462c5636a6f41a3f08a46
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SLC17A7_IL15-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PIK3C2G FHIP1A VCAN

1.85e-0420025348fd48990a6833066be314dc5b66b90893f7ea8f
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2|Neuronal / cells hierarchy compared to all cells using T-Statistic

PIK3C2G FHIP1A VCAN

1.85e-04200253d31e26387d879ee30731c497cea6aaf4746e40d9
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SLC17A7_IL15|Neuronal / cells hierarchy compared to all cells using T-Statistic

PIK3C2G FHIP1A VCAN

1.85e-04200253e5e97767beb4413e87c9817a60a5f1ee5209198a
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SCUBE1--L6|Neuronal / cells hierarchy compared to all cells using T-Statistic

PIK3C2G FHIP1A VCAN

1.85e-0420025357e8aea2c2f736ce37940dceb36224552dc33da1
ToppCellMonocytes-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

FOS VCAN

3.43e-0449252bf67f5dee042fd680c661db637fde715e48b14c5
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Prlr_(Entorhinal_cortex?)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

USP9Y PIK3C2G

6.03e-046525257d0d892dab8bc8465067feeff279c967a43b781
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Prlr_(Entorhinal_cortex?)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

USP9Y PIK3C2G

6.03e-0465252aba26f607f35c2920cdf956309285ad9e7b758a7
ToppCellCOVID-19_Convalescent-Classical_Monocyte|COVID-19_Convalescent / Disease condition and Cell class

FOS VCAN

7.40e-047225273db21be480920fc936f3a965495f5cf004e350a
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Chat.Synpr-Slc5a7_(Neuron.Gad1Gad2-Chat.Synpr-Slc5a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

USP9Y PIK3C2G

7.81e-04742520d705c42e7741b861ba5a9f1af83b2c5c6f23fb6
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Chat.Synpr-Slc5a7_(Neuron.Gad1Gad2-Chat.Synpr-Slc5a7)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

USP9Y PIK3C2G

7.81e-0474252c49bda52aa4ead9483c2f27d63458034e75699bd
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6|Thalamus / BrainAtlas - Mouse McCarroll V32

PRMT8 PIK3C2G

1.42e-031002521de3895e16f14ff32b901b18ce14d965afaa7e76
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Thalamus / BrainAtlas - Mouse McCarroll V32

PRMT8 PIK3C2G

1.42e-0310025220675fc2ffc5ab63047d38da083b50d470f3db19
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora|Thalamus / BrainAtlas - Mouse McCarroll V32

PRMT8 PIK3C2G

1.42e-03100252ff1bdb511700a041a90034d1d30dfc25f51d6c82
ToppCellmild_COVID-19-RBC|World / disease group, cell group and cell class (v2)

PHKG1 CA1

1.93e-0311725285210be67ddc31903764b7fa6d7029d9656753d3
ToppCellmild_COVID-19-RBC|mild_COVID-19 / disease group, cell group and cell class (v2)

PHKG1 CA1

2.03e-03120252cccea760901558ec18d5cbb71c7971c5a51da571
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma-6|TCGA-Endometrium / Sample_Type by Project: Shred V9

FOXN1 NDUFB9

2.31e-03128252f69f2a68cb2e272a9e239b4d247c537ae7abd8f0
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT1-AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FOXA2 FHIP1A

2.45e-03132252c6bf0b4b9e33b517629faf4559a21d7ba720ee6a
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOS VCAN

2.56e-0313525216ae3e31af2430ba5be1523fc18d491974940576
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l33|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LMTK2 GLCE

2.60e-03136252a43b3db1754c619d328a26a2ba6af4756629a723
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

LMTK2 FOS

2.83e-03142252ae495c8dd733f0fde66bddc281606543f21c0d4b
ToppCellBLOOD--(3)_MNP-(3)_Classical_Mono-1|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FOS VCAN

2.83e-03142252395f80e99be4a0ef07fb9d65c74399e7e67c9a8d
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PHKG1 KLHL30

2.91e-03144252f92e03dd784e31a9e5dbd4f4c3a6517ea19210cf
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PHKG1 PRMT8

2.91e-03144252fca32b38d23fa4d213e553b929604a2796e9a929
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRMT8 PIK3C2G

2.99e-03146252e887e9de895fd453faa703997ef372cc6410fc49
ToppCell368C-Lymphocytic-NK_cells-NK_cell_A|368C / Donor, Lineage, Cell class and subclass (all cells)

USP9Y CA1

2.99e-031462520e38e1fa40b1fcd1bb61f7af7cc2206846c192ae
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma-3|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

FOXA2 MGAM2

2.99e-03146252e55b4acecf4e363b5afa287c747c2e58c4597f3a
ToppCellMyeloid-Myeloid-C_(Monocyte)|Myeloid / shred on cell class and cell subclass (v4)

FOS VCAN

3.03e-03147252d7cfec8ec1b4854d783a1bb07b4f8d2b2fd22893
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

FOXA2 MGAM2

3.11e-0314925292a8931a51db619fb5f0638d319c02e7838f6559
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar-Club_cell|E18.5-samps / Age Group, Lineage, Cell class and subclass

STRN4 KLHL30

3.11e-0314925282edfecb7981d8c336cf9da7aa7e2b3f7a017a3f
ToppCellE16.5-samps|World / Age Group, Lineage, Cell class and subclass

TACC3 VCAN

3.11e-03149252e94d075f68c1c70c89fab50b1b765b5dda650d09
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar|E18.5-samps / Age Group, Lineage, Cell class and subclass

STRN4 KLHL30

3.11e-0314925214a01ae540db8a350ea26a350b2e6ce6c07639d9
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Mast|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CA1 NDST2

3.19e-031512529702575e47ececcf0a9f0f20a4a920dbb1ba5657
ToppCellLPS_only-Lymphocytic_NKT-iNKT/MAIT-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STRN4 GLCE

3.19e-031512527270b8bbfae659e110bd9d513b602120b25de3dd
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CA1 NDST2

3.19e-03151252673e4ab117b723c14d1df3804bbedc9e48284a9d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDK9 KLHL30

3.19e-03151252ea62e92ccb984f44559b434f35c1c4450767c8f1
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PHKG1 TACC3

3.23e-03152252f748ee34167f79ecda116aa1914afab47403385a
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FOXA2 FHIP1A

3.27e-03153252e7a074ea8232bacf924be78a244a8507c7e1ebc8
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDK9 FOS

3.27e-031532526a2a2379238133ce0ad714af130ffe02dd317247
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDK9 FOS

3.27e-03153252faa442dd925b2b09919e93c492ccc3f19803ad24
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOS CA1

3.32e-03154252f92d83c5f8b532fe5624f1cd352632f543d96ea9
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

PHKG1 KLHL30

3.36e-03155252d7e26696fd9c0a759524f331243db43059b33ed9
ToppCellHealthy_Control-Myeloid-Macrophages-FCN1_high|Healthy_Control / Condition, Lineage, Cell class and cell subclass

KLHL30 VCAN

3.36e-03155252cd2ccb4632713b4def3a1064599b78207e2e44c0
ToppCellMonocytes-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

FOS VCAN

3.36e-0315525282abfcee23ba08a1eb4208d367393285026e5388
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

FOS VCAN

3.36e-031552529d53caee196b5c2bbc90c4f54f693b64d4086065
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|368C / Donor, Lineage, Cell class and subclass (all cells)

PRMT8 USP9Y

3.40e-0315625225b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-IPC_like|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

PRMT8 GLCE

3.40e-031562527e6805ebc7bc2f9c5965321d16922c155719970f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-IPC_like-IPs_and_early_cortical_neurons|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

PRMT8 GLCE

3.40e-03156252741de05295b2d012ac8576378f37709a97c8fb50
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_memory_T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NDUFB9 FOS

3.40e-031562526146232d55ef41b1d3c3d7de4d876dcb7fc76f6f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PIK3C2G VCAN

3.44e-031572523216063174d794ff25b6743b6432ae1a9207614d
ToppCell368C-Lymphocytic-NK_cells-NK_cell_A|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

USP9Y CA1

3.44e-03157252542944030cd9b3f3559e64f9f6598694d74003c0
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G KLHL30

3.44e-0315725210989c7046fc859f137c7cef3296508d4476f11f
ToppCellMonocytes-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

FOS VCAN

3.49e-03158252c3096b3a914a1a15ebe3664613e94b951f8555fc
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

FOS VCAN

3.49e-03158252de65af8d3b8514b17978155f31975e2347b75251
ToppCell390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

TACC3 CA1

3.53e-031592520fbfdb18b7ed4bde077add13f2b3636e144b254f
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3C2G FOS

3.53e-0315925222427ad4ad2e797e4664e7a7b0514094f22a18b2
ToppCellMild-MAIT|Mild / Disease group and Cell class

FHIP1A VCAN

3.62e-031612520c1a04485708d5302600cdc2d7dac1cb76b4033a
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOS NDST2

3.62e-031612521f4614ae15bd2fc08e555cea4d0152c4a940d048
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXA2 FHIP1A

3.66e-03162252f2a87019ff9b466617e90c60d182ab7d14581cc9
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LMTK2 FHIP1A

3.71e-03163252431221a41d396b09170476179590eaf8a55266d8
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

FOXA2 PIK3C2G

3.71e-03163252961c3a1303108afd680365466045f3460a30a7b0
ToppCellnormal_Lymph_Node-Myeloid_cells-Monocytes|Myeloid_cells / Location, Cell class and cell subclass

FOS VCAN

3.71e-031632527d7f18e5c99be125e95bc180823430291b770d05
ToppCellfacs-GAT-Fat-24m-Lymphocytic-NK_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TACC3 KLHL30

3.71e-03163252e58863a462cc504bced627f004a47890ee2307ce
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LMTK2 FHIP1A

3.71e-031632521e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TACC3 KLHL30

3.75e-03164252ae09e5aabd1347b865474255e7411c04f63efb3b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FOXN1 TACC3

3.75e-0316425225758fb8112baf296264122d5d4121f1ebb3d0fa
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FOXN1 TACC3

3.75e-031642521642a67c66eeb77a218e7814e3cfe517d9822955
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMTK2 FOS

3.75e-03164252f9a2cc12179d5621c9174ec01d7418a71edd28d1
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PRMT8 FHIP1A

3.79e-0316525282530f96aaefe28a13bad0474bbad043f127a86c
ToppCellMonocytes-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

TACC3 VCAN

3.79e-0316525283d06210a50073fbb7082eabd8298dd355c40416
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PRMT8 FHIP1A

3.79e-031652520c714e852f912b5749de4cb0895406673979b2e6
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PIK3C2G FHIP1A

3.79e-031652527978eefcfc40175e933f7a8b64a5dd1c661dd1ac
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRMT8 FOXA2

3.84e-03166252575c325db88d6909cdf0d5e664bd9098b89d4401
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FHIP1A VCAN

3.84e-0316625236c443c9df9ed09fdede67df6f71eed1cca9cff1
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FHIP1A CA1

3.84e-03166252c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCellBasal-basal-4|World / Class top

PIK3C2G FOS

3.84e-031662522721772eb2a9f45c5e9aaf4d73d198fea11a3586
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FOXA2 GLCE

3.84e-031662526a6ed5c7a43fee9a8a9be42dfa99303815b8e8ef
ToppCell10x5'-Lung-Hematopoietic_progenitors|Lung / Manually curated celltypes from each tissue

TACC3 VCAN

3.88e-03167252dec18caf0475002d4ad3c7bc7fc3050cbc8e6bae
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

LMTK2 PRMT8

3.88e-031672529efb9511a211d0824bb97f82c1a5860c43d2138f
DiseaseProstatic Neoplasms

LMTK2 THYN1 ZNF292 NDST2

1.68e-03616254C0033578
DiseaseMalignant neoplasm of prostate

LMTK2 THYN1 ZNF292 NDST2

1.68e-03616254C0376358
Diseasegait measurement

TACC3 SPATA31E1

7.13e-03150252EFO_0007680

Protein segments in the cluster

PeptideGeneStartEntry
KKPWDMDDYSPSASG

VCAN

431

P13611
MNKHDWYEEYPTTPS

GLCE

491

O94923
KMGFSTAPDAPYTHW

PRMT8

321

Q9NR22
DFPATGWEYMKPDSE

PIK3C2G

626

O75747
MALPDFPDYHKWGFS

KLHL30

306

Q0D2K2
TWGMFAHDEPPAYKK

MGAM2

1106

Q2M2H8
DMDLSGSFYAADWEP

FOS

291

P01100
GFEWDDDFSPDPFMS

LMTK2

1416

Q8IWU2
PFSESGGDMKEWYHI

LIG3

126

P49916
WSALYDGDSPDPEMF

FHIP1A

521

Q05DH4
MASPDWGYDDKNGPE

CA1

1

P00915
PLESFWYHDMENPKS

BTD

316

P43251
NHDFFWSDPMPSDLK

CDK9

311

P50750
NEDHPGYGKEVDMWS

PHKG1

201

Q16816
KMEGHEPSDWSSYYA

FOXA2

6

Q9Y261
GSYHLDWDKMDDPNF

TACC3

401

Q9Y6A5
DWHPSEKAMYPDYFA

NDUFB9

106

Q9Y6M9
MTEHFPYFKTAPDGW

FOXN1

301

O15353
SEASFWGDPTPKHME

SPATA31E1

336

Q6ZUB1
EHPASFDWSSFKPMG

ZNF292

2576

O60281
HKGIDWYMDFFPVPS

NDST2

651

P52849
WYSKLMGDEPDLDPD

USP9Y

701

O00507
YPKDMFDPHGWSEDS

SAP30BP

181

Q9UHR5
HYDPSSKEDNPKWSM

THYN1

146

Q9P016
HSWKIPDLSMDPYDG

STRN4

516

Q9NRL3