Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF141 ZNF143 ZNF527 ZNF586 ZNF678 ZNF177 ZNF626 ZNF623 ZNF891 ZBTB24 ZNF551 PURB ZNF506 NLRC5 ZNF770 ZNF81 ZNF468 ZNF107 ZNF426 ZNF681 ZNF729 ZNF502 ZNF567 ZNF555 ZNF560 CPHXL2 GLIS3 ZNF485 ZNF510 POU5F1B ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF66 ZNF888 ZNF525 ZNF30 ZNF90 ZNF99 TCFL5 GLIS1	1.75e-09	1459	242	46	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF141 ZNF143 ZNF527 ZNF586 ZNF678 ZNF177 ZNF626 ZNF623 ZNF891 ZBTB24 ZNF551 PURB ZNF506 ZNF770 ZNF81 ZNF468 ZNF107 ZNF426 ZNF681 ZNF729 ZNF502 ZNF555 ZNF560 CPHXL2 GLIS3 ZNF485 ZNF510 POU5F1B ZNF416 ZNF284 ZNF675 ZNF28 GTF2I ZNF43 ZNF92 ZFP1 ZNF66 ZNF888 ZNF525 ZNF30 ZNF90 ZNF99 TCFL5 GLIS1	6.02e-09	1412	242	44	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF141 ZNF143 ZNF527 ZNF586 ZNF678 ZNF626 ZNF623 ZBTB24 ZNF551 ZNF506 NLRC5 ZNF770 ZNF81 ZNF468 ZNF107 ZNF426 ZNF681 ZNF729 ZNF502 ZNF567 CPHXL2 GLIS3 ZNF485 POU5F1B ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF66 ZNF888 ZNF525 ZNF30 ZNF90 ZNF99 TCFL5 GLIS1	1.41e-08	1244	242	40	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF141 ZNF143 ZNF527 ZNF586 ZNF678 ZNF626 ZNF623 ZBTB24 ZNF551 ZNF506 NLRC5 ZNF770 ZNF81 ZNF468 ZNF107 ZNF426 ZNF681 ZNF729 ZNF502 ZNF567 CPHXL2 GLIS3 ZNF485 POU5F1B ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF66 ZNF888 ZNF525 ZNF30 ZNF90 ZNF99 TCFL5 GLIS1	2.54e-08	1271	242	40	GO:0000987
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH14 DYNC1H1 DYNC2H1 DNAH11	5.63e-05	18	242	4	GO:0008569
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH14 DYNC1H1 DYNC2H1 DNAH11	3.43e-04	28	242	4	GO:0051959
GeneOntologyMolecularFunction	cysteine-S-conjugate beta-lyase activity	KYAT3 CTH	4.35e-04	3	242	2	GO:0047804
GeneOntologyMolecularFunction	protein serine kinase activity	SMG1 TSSK2 PAK6 MAP3K5 NEK1 PIK3CA PAK5 HIPK3 CSNK1D CSNK1E DYRK1B ATM MAP3K21	5.15e-04	363	242	13	GO:0106310
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZBTB24 PURB ZNF107 ZNF681 ZNF729 GLIS3 POU5F1B ZNF28 ZNF43 ZNF99 TCFL5 GLIS1	5.61e-04	320	242	12	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	ZBTB24 PURB ZNF107 ZNF681 ZNF729 GLIS3 POU5F1B ZNF28 ZNF43 ZNF99 TCFL5 GLIS1	6.61e-04	326	242	12	GO:0001217
GeneOntologyMolecularFunction	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	TOP2A TOP2B	8.64e-04	4	242	2	GO:0003918
Domain	KRAB	ZNF141 ZNF527 ZNF586 ZNF177 ZNF626 ZNF891 ZNF551 ZNF506 ZNF81 ZNF468 ZNF426 ZNF681 ZNF729 ZNF567 ZNF555 ZNF560 ZNF485 ZNF510 ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF30 ZNF90 ZNF99	1.72e-15	358	236	29	PS50805
Domain	KRAB	ZNF141 ZNF527 ZNF586 ZNF177 ZNF626 ZNF891 ZNF551 ZNF506 ZNF81 ZNF468 ZNF426 ZNF681 ZNF729 ZNF567 ZNF555 ZNF560 ZNF485 ZNF510 ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF30 ZNF90 ZNF99	1.72e-15	358	236	29	PF01352
Domain	zf-C2H2	ZNF141 ZNF143 ZNF527 ZNF586 ZNF678 ZNF177 ZNF626 ZNF623 ZNF891 ZBTB24 ZNF551 ZNF506 ZNF770 ZNF81 ZNF468 ZNF107 ZNF426 ZNF681 ZNF729 ZNF502 ZNF567 ZNF555 ZNF560 GLIS3 ZNF485 ZNF510 ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF525 ZNF30 ZNF90 ZNF99 GLIS1	3.59e-15	693	236	39	PF00096
Domain	KRAB	ZNF141 ZNF527 ZNF586 ZNF177 ZNF626 ZNF891 ZNF551 ZNF506 ZNF81 ZNF468 ZNF426 ZNF681 ZNF729 ZNF567 ZNF555 ZNF560 ZNF485 ZNF510 ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF30 ZNF90 ZNF99	3.80e-15	369	236	29	SM00349
Domain	zf-C2H2_6	ZNF141 ZNF527 ZNF586 ZNF626 ZNF891 ZBTB24 ZNF551 ZNF506 ZNF770 ZNF468 ZNF107 ZNF426 ZNF681 ZNF729 ZNF502 ZNF567 ZNF555 ZNF560 ZNF416 ZNF284 ZNF675 ZNF43 ZNF92 ZNF667 ZNF30 ZNF90 ZNF99	3.97e-15	314	236	27	PF13912
Domain	KRAB	ZNF141 ZNF527 ZNF586 ZNF177 ZNF626 ZNF891 ZNF551 ZNF506 ZNF81 ZNF468 ZNF426 ZNF681 ZNF729 ZNF567 ZNF555 ZNF560 ZNF485 ZNF510 ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF30 ZNF90 ZNF99	4.08e-15	370	236	29	IPR001909
Domain	Znf_C2H2/integrase_DNA-bd	ZNF141 ZNF143 ZNF527 ZNF586 ZNF177 ZNF626 ZNF623 ZNF891 ZBTB24 ZNF551 ZNF506 ZNF770 ZNF81 ZNF468 ZNF107 ZNF426 ZNF681 ZNF729 ZNF502 ZNF567 ZNF555 ZNF560 GLIS3 ZNF485 ZNF510 ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF30 ZNF90 ZNF99 GLIS1	1.05e-13	694	236	37	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF141 ZNF143 ZNF527 ZNF586 ZNF678 ZNF177 ZNF626 ZNF623 ZNF891 ZBTB24 ZNF551 ZNF506 ZNF770 ZNF81 ZNF468 ZNF107 ZNF426 ZNF681 ZNF729 ZNF502 ZNF567 ZNF555 ZNF560 GLIS3 ZNF485 ZNF510 ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF525 ZNF30 ZNF90 ZNF99 GLIS1	1.32e-13	775	236	39	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF141 ZNF143 ZNF527 ZNF586 ZNF678 ZNF177 ZNF626 ZNF623 ZNF891 ZBTB24 ZNF551 ZNF506 ZNF770 ZNF81 ZNF468 ZNF107 ZNF426 ZNF681 ZNF729 ZNF502 ZNF567 ZNF555 ZNF560 GLIS3 ZNF485 ZNF510 ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF525 ZNF30 ZNF90 ZNF99 GLIS1	1.43e-13	777	236	39	PS00028
Domain	-	ZNF141 ZNF143 ZNF527 ZNF586 ZNF626 ZNF623 ZNF891 ZBTB24 ZNF551 ZNF506 ZNF770 ZNF81 ZNF468 ZNF107 ZNF426 ZNF681 ZNF729 ZNF502 ZNF567 ZNF555 ZNF560 GLIS3 ZNF485 ZNF510 ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF30 ZNF90 ZNF99 GLIS1	2.78e-13	679	236	36	3.30.160.60
Domain	Znf_C2H2	ZNF141 ZNF143 ZNF527 ZNF586 ZNF678 ZNF177 ZNF626 ZNF623 ZNF891 ZBTB24 ZNF551 ZNF506 ZNF770 ZNF81 ZNF468 ZNF107 ZNF426 ZNF681 ZNF729 ZNF502 ZNF567 ZNF555 ZNF560 GLIS3 ZNF485 ZNF510 ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF525 ZNF30 ZNF90 ZNF99 GLIS1	4.35e-13	805	236	39	IPR007087
Domain	ZnF_C2H2	ZNF141 ZNF143 ZNF527 ZNF586 ZNF678 ZNF177 ZNF626 ZNF623 ZNF891 ZBTB24 ZNF551 ZNF506 ZNF770 ZNF81 ZNF468 ZNF107 ZNF426 ZNF681 ZNF729 ZNF502 ZNF567 ZNF555 ZNF560 GLIS3 ZNF485 ZNF510 ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF525 ZNF30 ZNF90 ZNF99 GLIS1	4.89e-13	808	236	39	SM00355
Domain	Znf_C2H2-like	ZNF141 ZNF143 ZNF527 ZNF586 ZNF177 ZNF626 ZNF623 ZNF891 ZBTB24 ZNF551 ZNF506 ZNF770 ZNF81 ZNF468 ZNF107 ZNF426 ZNF681 ZNF729 ZNF502 ZNF567 ZNF555 ZNF560 GLIS3 ZNF485 ZNF510 ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF30 ZNF90 ZNF99 GLIS1	6.36e-12	796	236	37	IPR015880
Domain	Dynein_heavy_chain_D4_dom	DNAH14 DYNC1H1 DYNC2H1 DNAH11	2.25e-05	14	236	4	IPR024317
Domain	Dynein_HC_stalk	DNAH14 DYNC1H1 DYNC2H1 DNAH11	2.25e-05	14	236	4	IPR024743
Domain	MT	DNAH14 DYNC1H1 DYNC2H1 DNAH11	2.25e-05	14	236	4	PF12777
Domain	AAA_8	DNAH14 DYNC1H1 DYNC2H1 DNAH11	2.25e-05	14	236	4	PF12780
Domain	DHC_fam	DNAH14 DYNC1H1 DYNC2H1 DNAH11	3.04e-05	15	236	4	IPR026983
Domain	Dynein_heavy	DNAH14 DYNC1H1 DYNC2H1 DNAH11	3.04e-05	15	236	4	PF03028
Domain	Dynein_heavy_dom	DNAH14 DYNC1H1 DYNC2H1 DNAH11	3.04e-05	15	236	4	IPR004273
Domain	WASP_C	PAK6 WASL PAK5	6.72e-05	7	236	3	IPR011026
Domain	PDZ	MAGI1 FRMPD4 PARD6G ARHGEF11 DLG4 RGS12 GIPC3 SNTG2 SCRIB	7.77e-05	141	236	9	PF00595
Domain	DHC_N1	DYNC1H1 DYNC2H1 DNAH11	1.06e-04	8	236	3	PF08385
Domain	Dynein_heavy_dom-1	DYNC1H1 DYNC2H1 DNAH11	1.06e-04	8	236	3	IPR013594
Domain	PDZ	MAGI1 FRMPD4 PARD6G ARHGEF11 DLG4 RGS12 GIPC3 SNTG2 SCRIB	1.13e-04	148	236	9	SM00228
Domain	-	MAGI1 FRMPD4 PARD6G ARHGEF11 DLG4 RGS12 GIPC3 SNTG2 SCRIB	1.25e-04	150	236	9	2.30.42.10
Domain	PDZ	MAGI1 FRMPD4 PARD6G ARHGEF11 DLG4 RGS12 GIPC3 SNTG2 SCRIB	1.31e-04	151	236	9	PS50106
Domain	PDZ	MAGI1 FRMPD4 PARD6G ARHGEF11 DLG4 RGS12 GIPC3 SNTG2 SCRIB	1.38e-04	152	236	9	IPR001478
Domain	-	TOP2A TOP2B	1.59e-04	2	236	2	3.40.50.670
Domain	DTHCT	TOP2A TOP2B	1.59e-04	2	236	2	IPR012542
Domain	DNA_gyraseB	TOP2A TOP2B	1.59e-04	2	236	2	PF00204
Domain	-	TOP2A TOP2B	1.59e-04	2	236	2	3.90.199.10
Domain	TopoIIA_CS	TOP2A TOP2B	1.59e-04	2	236	2	IPR018522
Domain	Topo_IIA	TOP2A TOP2B	1.59e-04	2	236	2	IPR001241
Domain	NatA_aux_su	NAA16 NAA15	1.59e-04	2	236	2	IPR021183
Domain	DNA_topoisoIV	TOP2A TOP2B	1.59e-04	2	236	2	PF00521
Domain	Topo_IIA_A/C_ab	TOP2A TOP2B	1.59e-04	2	236	2	IPR013758
Domain	Topo_IIA_A_a	TOP2A TOP2B	1.59e-04	2	236	2	IPR013757
Domain	Topo_IIA_cen_dom	TOP2A TOP2B	1.59e-04	2	236	2	IPR013759
Domain	TOP4c	TOP2A TOP2B	1.59e-04	2	236	2	SM00434
Domain	TOP2c	TOP2A TOP2B	1.59e-04	2	236	2	SM00433
Domain	Topo_IIA-like_dom	TOP2A TOP2B	1.59e-04	2	236	2	IPR013760
Domain	Topo_IIA_bsu_dom2	TOP2A TOP2B	1.59e-04	2	236	2	IPR013506
Domain	DTHCT	TOP2A TOP2B	1.59e-04	2	236	2	PF08070
Domain	NARP1	NAA16 NAA15	1.59e-04	2	236	2	PF12569
Domain	-	TOP2A TOP2B	1.59e-04	2	236	2	1.10.268.10
Domain	TOPRIM_C	TOP2A TOP2B	1.59e-04	2	236	2	IPR031660
Domain	TOPRIM_C	TOP2A TOP2B	1.59e-04	2	236	2	PF16898
Domain	ATM/Tel1	SMG1 ATM	1.59e-04	2	236	2	IPR015519
Domain	Topo_IIA_A/C	TOP2A TOP2B	1.59e-04	2	236	2	IPR002205
Domain	TOPOISOMERASE_II	TOP2A TOP2B	1.59e-04	2	236	2	PS00177
Domain	Arg_repress_C-like	TOP2A TOP2B	4.73e-04	3	236	2	IPR024946
Domain	-	TOP2A TOP2B	4.73e-04	3	236	2	3.30.1360.40
Domain	Dynein_heavy_dom-2	DYNC1H1 DYNC2H1 DNAH11	6.54e-04	14	236	3	IPR013602
Domain	DHC_N2	DYNC1H1 DYNC2H1 DNAH11	6.54e-04	14	236	3	PF08393
Domain	ATPase_dyneun-rel_AAA	DYNC1H1 DYNC2H1 DNAH11	6.54e-04	14	236	3	IPR011704
Domain	AAA_5	DYNC1H1 DYNC2H1 DNAH11	6.54e-04	14	236	3	PF07728
Domain	PI3/4_kinase_CS	SMG1 PIK3CA ATM	8.10e-04	15	236	3	IPR018936
Domain	G8_domain	PKHD1 PKHD1L1	9.38e-04	4	236	2	IPR019316
Domain	Toprim	TOP2A TOP2B	9.38e-04	4	236	2	PF01751
Domain	G8	PKHD1 PKHD1L1	9.38e-04	4	236	2	PS51484
Domain	G8	PKHD1 PKHD1L1	9.38e-04	4	236	2	SM01225
Domain	G8	PKHD1 PKHD1L1	9.38e-04	4	236	2	PF10162
Domain	Toprim_domain	TOP2A TOP2B	9.38e-04	4	236	2	IPR006171
Domain	TOPRIM	TOP2A TOP2B	9.38e-04	4	236	2	PS50880
Domain	-	SMG1 PIK3CA ATM	9.88e-04	16	236	3	1.10.1070.11
Domain	PI3Kc	SMG1 PIK3CA ATM	9.88e-04	16	236	3	SM00146
Domain	PBD	PAK6 WASL PAK5	9.88e-04	16	236	3	SM00285
Domain	PH_dom-like	FRMPD4 SWAP70 ARHGEF11 MTMR10 JAK1 FERMT2 APBB1IP GULP1 WASL RASGRF1 RGS12 APPL1 SNTG2 PLCE1	1.09e-03	426	236	14	IPR011993
Domain	PBD	PAK6 WASL PAK5	1.19e-03	17	236	3	PF00786
Domain	PI3_PI4_kinase	SMG1 PIK3CA ATM	1.41e-03	18	236	3	PF00454
Domain	PI3_4_KINASE_1	SMG1 PIK3CA ATM	1.41e-03	18	236	3	PS00915
Domain	PI3_4_KINASE_2	SMG1 PIK3CA ATM	1.41e-03	18	236	3	PS00916
Domain	HATPase_c	MORC4 TOP2A TOP2B	1.41e-03	18	236	3	SM00387
Domain	PI3/4_kinase_cat_dom	SMG1 PIK3CA ATM	1.41e-03	18	236	3	IPR000403
Domain	PI3_4_KINASE_3	SMG1 PIK3CA ATM	1.41e-03	18	236	3	PS50290
Domain	U2AF_small	U2AF1L4 U2AF1	1.55e-03	5	236	2	IPR009145
Domain	FATC	SMG1 ATM	1.55e-03	5	236	2	PF02260
Domain	HATPase_c	MORC4 TOP2A TOP2B	1.66e-03	19	236	3	PF02518
Domain	CRIB	PAK6 WASL PAK5	1.94e-03	20	236	3	PS50108
Domain	-	MORC4 TOP2A TOP2B	1.94e-03	20	236	3	3.30.565.10
Domain	Ig_E-set	PKHD1 LY86 FLNB PKHD1L1 TGM3 PLXNC1	2.07e-03	104	236	6	IPR014756
Domain	HATPase_C	MORC4 TOP2A TOP2B	2.24e-03	21	236	3	IPR003594
Domain	CRIB_dom	PAK6 WASL PAK5	2.24e-03	21	236	3	IPR000095
Domain	RIH_assoc-dom	RYR1 ITPR3	2.31e-03	6	236	2	IPR013662
Domain	PbH1	PKHD1 PKHD1L1	2.31e-03	6	236	2	SM00710
Domain	Ins145_P3_rec	RYR1 ITPR3	2.31e-03	6	236	2	PF08709
Domain	RIH_assoc	RYR1 ITPR3	2.31e-03	6	236	2	PF08454
Domain	RIH_dom	RYR1 ITPR3	2.31e-03	6	236	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 ITPR3	2.31e-03	6	236	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 ITPR3	2.31e-03	6	236	2	IPR015925
Domain	FAT	SMG1 ATM	2.31e-03	6	236	2	PS51189
Domain	FATC	SMG1 ATM	2.31e-03	6	236	2	PS51190
Domain	-	RYR1 ITPR3	2.31e-03	6	236	2	1.25.10.30
Domain	FATC_dom	SMG1 ATM	2.31e-03	6	236	2	IPR003152
Domain	RYDR_ITPR	RYR1 ITPR3	2.31e-03	6	236	2	PF01365
Domain	PbH1	PKHD1 PKHD1L1	2.31e-03	6	236	2	IPR006626
Domain	PIK_FAT	SMG1 ATM	2.31e-03	6	236	2	IPR014009
Domain	FATC	SMG1 ATM	2.31e-03	6	236	2	SM01343
Domain	RRM	AKAP17A U2AF1L4 U2AF1 CELF6 ENOX1 RBM45 PUF60 CELF2 ELAVL3	2.68e-03	230	236	9	PS50102
Pubmed	Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.	ZNF626 ZNF506 ZNF107 ZNF681 ZNF729 ZNF43 ZNF99	1.08e-09	29	245	7	14563677
Pubmed	Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.	ZNF107 ZNF681 ZNF729 ZNF43 ZNF99	4.72e-08	15	245	5	15885501
Pubmed	Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.	ZNF107 ZNF43 ZNF92 ZNF90 ZNF99	6.83e-08	16	245	5	8467795
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF678 ZNF626 ZNF468 ZNF107 ZNF681 ZNF567 ZNF555 ZNF485 ZNF92 ZFP1 ZNF90	7.42e-08	181	245	11	37372979
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	AKAP17A TUBG2 DIS3L USP9Y MTMR10 JAK1 U2AF1 NAA25 SNX6 DLG4 HERC2 FHL1 MBD4 DYNC1H1 FLNB WASL KIF21A RBP4 HECTD4 BRCC3 WRAP53 PAICS ZNF92 APPL1 ATM SCRIB USP33 LGI1	1.39e-07	1285	245	28	35914814
Pubmed	CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1.	GAPVD1 CSNK1D CSNK1E	3.45e-07	3	245	3	32321936
Pubmed	Recombinant human cytoplasmic dynein heavy chain 1 and 2: observation of dynein-2 motor activity in vitro.	DYNC1H1 DYNC2H1 DYNC2LI1	3.45e-07	3	245	3	21723285
Pubmed	Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.	TSSK2 PAK6 NEK1 CSNK1D CSNK1E	3.98e-07	22	245	5	22305495
Pubmed	Functional analysis of the SRY-KRAB interaction in mouse sex determination.	ZNF107 ZNF729 ZNF43 ZNF99	4.88e-07	10	245	4	18588511
Pubmed	Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.	ZNF107 ZNF729 ZNF43 ZNF99	7.63e-07	11	245	4	15469996
Pubmed	Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk.	MAGI1 INPP4A ARHGEF11 FLNB CSNK1D SCRIB	9.69e-07	47	245	6	32253237
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	GAPVD1 BCAS3 PYGB DIAPH3 DYNC1H1 FLNB NAA15 FARSB BRCC3 NUP214 PAICS CDC37 GTF2I DOCK7 KYAT3 SCRIB	1.48e-06	534	245	16	35032548
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	MAGI1 GAPVD1 AKAP17A PAK6 ZBTB24 FABP5 JAK1 U2AF1 NAA25 HERC2 DYNC1H1 VIL1 PUF60 POLE PAK5 BIRC5 BRCC3 ODC1 PAICS CDC37 GTF2I CNOT6L POLR1E CSNK1D CSNK1E MAP3K21	1.57e-06	1284	245	26	17353931
Pubmed	Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.	ZNF107 ZNF729 ZNF43 ZNF99	1.63e-06	13	245	4	19850934
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	GAPVD1 INPP4A NEK1 BRCA2 NAV1 DIAPH3 FLNB L3MBTL2 NUP214 POU5F1B IDH3A MORC4 GTF2I DOCK7	1.89e-06	418	245	14	34709266
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	ZNF143 BCAS3 MTMR10 SERPINB9 FERMT2 NOS2 ZNF426 PAPPA2 COL12A1 HECTD4 FARSB BIRC5 USP33	2.13e-06	363	245	13	14691545
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF551 ZNF28 ZNF43 ZFP1 ZNF30	2.44e-06	31	245	5	2288909
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	MAGI1 DAG1 PAK6 MTMR10 PIK3CA NAV1 MICAL3 DIAPH3 FERMT2 WASL GNL3L OAS1 RGS12 PLXNC1 DOCK7 SCRIB	3.34e-06	569	245	16	30639242
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	UTP6 GAPVD1 ZC3H13 ITPR3 PYGB HERC2 DYNC1H1 FLNB NAA15 PUF60 POLE NUP214 PAICS TGM3 GTF2I DOCK7 ATM	4.58e-06	653	245	17	22586326
Pubmed	Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.	MAGI1 DLG4 RGS12 SNTG2 SCRIB	5.25e-06	36	245	5	26053890
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	UTP6 GAPVD1 MCMBP MTMR10 ITPR3 SNX6 DLG4 DIAPH3 FLNB EPM2A NAA15 POLE FARSB BRCC3 NUP214 PAICS CDC37 GTF2I CSNK1D CSNK1E DUSP10	6.50e-06	974	245	21	28675297
Pubmed	SCFβ-TrCP-mediated degradation of TOP2β promotes cancer cell survival in response to chemotherapeutic drugs targeting topoisomerase II.	CSNK1D ATM TOP2B	6.80e-06	6	245	3	32015321
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	GAPVD1 TUBG2 CNOT6 MICAL3 HERC2 DYNC1H1 NAA16 NAA15 TCN1 L3MBTL2 TOPBP1 BIRC5 NUP214 WRAP53 NBAS GTF2I CNOT6L CSNK1E ZFP1 ATM SCRIB TOP2A TOP2B	8.49e-06	1155	245	23	20360068
Pubmed	A human MAP kinase interactome.	MAGI1 PAK6 ARHGEF11 MAP3K5 NAV1 HERC2 CPLANE1 WASL PAK5 NUP214 HIPK3 DYRK1B DUSP10 MAP3K21	1.06e-05	486	245	14	20936779
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	GAPVD1 DIS3L ARHGEF11 BRCA2 MICAL3 HERC2 FHL1 CPLANE1 FERMT2 DYNC1H1 WASL L3MBTL2 RGS12 TGM3 DYNC2LI1 CSNK1D CSNK1E SNX18 TOP2A	1.16e-05	853	245	19	28718761
Pubmed	Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.	SPON1 DCUN1D5 DYNC2H1 CNOT6L	1.31e-05	21	245	4	24057671
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAGI1 GAPVD1 MCMBP BCAS3 TSSK2 PAK6 NEK1 NAV1 NAA15 PAK5 BRCC3 RGS12 CSNK1D CSNK1E DYRK1B DOCK7 ANKRD11 SCRIB MAP3K21	1.32e-05	861	245	19	36931259
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	GAPVD1 USP9Y ARHGEF11 SLITRK1 CROCC2 MICAL3 GNL3L NUP214 PAICS RGS12 ERCC6L2 ANKRD11 ATM ZNF99	1.35e-05	497	245	14	36774506
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	SMG1 RYR1 MAP3K5 SNX6 MED12L FHL1 ZNF426 FLNB WASL COL12A1 GLIS3 ITGB1BP2 APPL1 PLCE1	1.35e-05	497	245	14	23414517
Pubmed	The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.	ZNF43 ZNF92 ZNF90	1.88e-05	8	245	3	2023909
Pubmed	HIV-1 uncoating is facilitated by dynein and kinesin 1.	DYNC1H1 DYNC2H1 DYNC2LI1	1.88e-05	8	245	3	25231297
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF143 ZC3H13 ZNF626 ZNF623 ZBTB24 ZNF506 ZNF426 ZNF681 ZNF729 DCUN1D5 GLIS3 POU5F1B PKHD1L1 GTF2I ZNF43 PLXNC1 ZNF99 GLIS1	1.97e-05	808	245	18	20412781
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF107 ZNF681 ZNF729 ZNF43 ZNF99	2.47e-05	49	245	5	9630514
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	UTP6 GAPVD1 MCMBP U2AF1 NOP9 FHL1 DYNC1H1 FLNB GNL3L DYNC2H1 PUF60 POLE FARSB NUP214 IDH3A PAICS CDC37 TGM3 GTF2I GUCY1B2 CSNK1E DOCK7 ATM TOP2A TOP2B	2.87e-05	1425	245	25	30948266
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZBTB24 ZNF770 HERC2 MBD4 ZNF567 GNL3L DCUN1D5 L3MBTL2 TOPBP1 BIRC5 GTF2I POLR1E ZFP1 TOP2A TOP2B	3.12e-05	608	245	15	36089195
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	MCMBP THNSL1 AFP ZNF770 HERC2 WDR24 FLG FLNB RBM45 DYNC2H1 BRCC3 NUP214 IDH3A CDC37 TGM3 GTF2I POLR1E DOCK7 SCRIB USP33	3.38e-05	1005	245	20	19615732
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRMPD4 RHOBTB2 NAV1 MICAL3 ANKRD12 DYNC1H1 NUP214 EPG5 DOCK7 SCRIB USP33 PLCE1	3.62e-05	407	245	12	12693553
Pubmed	Convergent functional genomics of oligodendrocyte differentiation identifies multiple autoinhibitory signaling circuits.	BCAS3 PAK5 DUSP10	4.00e-05	10	245	3	19139271
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	BCAS3 ARHGEF11 RYR1 MAP3K5 ITPR3 RAB43 NAV1 NLRC5 PYGB MICAL3 HERC2 ZNF426 DYNC1H1 WDR24 PUF60 POLE HECTD4 NUP214 WRAP53 ANKRD11 POFUT1	4.17e-05	1105	245	21	35748872
Pubmed	DNA topoisomerase II is dispensable for oocyte meiotic resumption but is essential for meiotic chromosome condensation and separation in mice.	TOP2A TOP2B	4.94e-05	2	245	2	24048577
Pubmed	Ataxia telangiectasia mutated-dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor.	ATM TOP2A	4.94e-05	2	245	2	23163762
Pubmed	Use of divalent metal ions in the dna cleavage reaction of human type II topoisomerases.	TOP2A TOP2B	4.94e-05	2	245	2	19222228
Pubmed	SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress.	SMG1 ATM	4.94e-05	2	245	2	31565865
Pubmed	Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation.	TOP2A TOP2B	4.94e-05	2	245	2	1331984
Pubmed	CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle development.	CNOT6 CNOT6L	4.94e-05	2	245	2	34788619
Pubmed	Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle.	CSNK1D CSNK1E	4.94e-05	2	245	2	9632646
Pubmed	hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress.	SMG1 ATM	4.94e-05	2	245	2	18332866
Pubmed	Effect of personal exposure to black carbon on changes in allergic asthma gene methylation measured 5 days later in urban children: importance of allergic sensitization.	NOS2 IL4	4.94e-05	2	245	2	28588744
Pubmed	Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development.	TOP2A TOP2B	4.94e-05	2	245	2	1380833
Pubmed	Genetic analysis of the cytoplasmic dynein subunit families.	DYNC1H1 DYNC2H1	4.94e-05	2	245	2	16440056
Pubmed	Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes.	TOP2A TOP2B	4.94e-05	2	245	2	2556712
Pubmed	Transcriptional activity of multiple copies of a subtelomerically located olfactory receptor gene that is polymorphic in number and location.	OR4F4 OR4F17	4.94e-05	2	245	2	11689484
Pubmed	Comparative sequencing of a multicopy subtelomeric region containing olfactory receptor genes reveals multiple interactions between non-homologous chromosomes.	OR4F4 OR4F17	4.94e-05	2	245	2	11689483
Pubmed	Alpha-fetoprotein and Fanconi Anemia: Relevance to DNA Repair and Breast Cancer Susceptibility.	BRCA2 AFP	4.94e-05	2	245	2	27690720
Pubmed	Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies.	TOP2A TOP2B	4.94e-05	2	245	2	17578914
Pubmed	Phosphatidylinositol 3-kinase mediates activation of ATM by high NaCl and by ionizing radiation: Role in osmoprotective transcriptional regulation.	PIK3CA ATM	4.94e-05	2	245	2	16728507
Pubmed	A DNA-topoisomerase-II-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell-cycle regulator.	TOPBP1 TOP2B	4.94e-05	2	245	2	9461304
Pubmed	Arginine-nitric oxide-polyamine metabolism in periodontal disease.	NOS2 ODC1	4.94e-05	2	245	2	20831369
Pubmed	TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution.	TOPBP1 TOP2A	4.94e-05	2	245	2	25762097
Pubmed	Mechanism of suppression of nitric oxide synthase expression by interleukin-4 in primary mouse macrophages.	NOS2 IL4	4.94e-05	2	245	2	7507968
Pubmed	Molecular cloning and characterization of the human topoisomerase IIalpha and IIbeta genes: evidence for isoform evolution through gene duplication.	TOP2A TOP2B	4.94e-05	2	245	2	10095062
Pubmed	Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.	TOP2A TOP2B	4.94e-05	2	245	2	14996935
Pubmed	Clinical significance of PIK3CA and survivin in primary adenosquamous lung carcinoma.	PIK3CA BIRC5	4.94e-05	2	245	2	24838432
Pubmed	Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons.	TOP2A TOP2B	4.94e-05	2	245	2	28700616
Pubmed	Predictors and mechanisms of epilepsy occurrence in cerebral gliomas: What to look for in clinicopathology.	TOP2A TOP2B	4.94e-05	2	245	2	28087392
Pubmed	Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint.	TOP2A TOP2B	4.94e-05	2	245	2	28472494
Pubmed	Inducible NO synthase confers chemoresistance in head and neck cancer by modulating survivin.	NOS2 BIRC5	4.94e-05	2	245	2	19130609
Pubmed	Inhibition of microtubules and dynein rescues human immunodeficiency virus type 1 from owl monkey TRIMCyp-mediated restriction in a cellular context-specific fashion.	DYNC1H1 DYNC2H1	4.94e-05	2	245	2	25502651
Pubmed	Association between pathogenic germline mutations in BRCA2 and ATM and tumor-infiltrating lymphocytes in primary prostate cancer.	BRCA2 ATM	4.94e-05	2	245	2	34533610
Pubmed	Effects of altered expression and activity levels of CK1δ and ɛ on tumor growth and survival of colorectal cancer patients.	CSNK1D CSNK1E	4.94e-05	2	245	2	25404202
Pubmed	RNA interference knockdown of hU2AF35 impairs cell cycle progression and modulates alternative splicing of Cdc25 transcripts.	U2AF1 RASGRF1	4.94e-05	2	245	2	16855028
Pubmed	The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues.	TOP2A TOP2B	4.94e-05	2	245	2	9155056
Pubmed	Inducible nitric oxide synthase and survivin messenger RNA expression in hepatocellular carcinoma.	NOS2 BIRC5	4.94e-05	2	245	2	12374680
Pubmed	Active heterodimers are formed from human DNA topoisomerase II alpha and II beta isoforms.	TOP2A TOP2B	4.94e-05	2	245	2	8710863
Pubmed	Survival of BRCA2-Deficient Cells Is Promoted by GIPC3, a Novel Genetic Interactor of BRCA2.	BRCA2 GIPC3	4.94e-05	2	245	2	29021281
Pubmed	Evidence for a mutant allele of the gene for DNA topoisomerase II in adriamycin-resistant P388 murine leukemia cells.	TOP2A TOP2B	4.94e-05	2	245	2	2555055
Pubmed	Doxorubicin-induced cardiotoxicity is maturation dependent due to the shift from topoisomerase IIα to IIβ in human stem cell derived cardiomyocytes.	TOP2A TOP2B	4.94e-05	2	245	2	31106979
Pubmed	A biochemical analysis of topoisomerase II alpha and beta kinase activity found in HIV-1 infected cells and virus.	TOP2A TOP2B	4.94e-05	2	245	2	16091284
Pubmed	CK1δ and CK1ε are components of human 40S subunit precursors required for cytoplasmic 40S maturation.	CSNK1D CSNK1E	4.94e-05	2	245	2	24424021
Pubmed	Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions.	GFUS POFUT1	4.94e-05	2	245	2	21464368
Pubmed	NEK1 and DYNC2H1 are both involved in short rib polydactyly Majewski type but not in Beemer Langer cases.	NEK1 DYNC2H1	4.94e-05	2	245	2	22499340
Pubmed	Mining topoisomerase isoforms in gastric cancer.	TOP2A TOP2B	4.94e-05	2	245	2	32535049
Pubmed	Involvement of human topoisomerase II isoforms in HIV-1 reverse transcription.	TOP2A TOP2B	4.94e-05	2	245	2	23399433
Pubmed	ATM-ROS-iNOS axis regulates nitric oxide mediated cellular senescence.	NOS2 ATM	4.94e-05	2	245	2	27845209
Pubmed	Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse.	PIK3CA KLRK1	4.94e-05	2	245	2	17923698
Pubmed	Identification of Glis1, a novel Gli-related, Kruppel-like zinc finger protein containing transactivation and repressor functions.	GLIS3 GLIS1	4.94e-05	2	245	2	12042312
Pubmed	Enhanced processing of UVA-irradiated DNA by human topoisomerase II in living cells.	TOP2A TOP2B	4.94e-05	2	245	2	15044480
Pubmed	C-terminal regions of topoisomerase IIalpha and IIbeta determine isoform-specific functioning of the enzymes in vivo.	TOP2A TOP2B	4.94e-05	2	245	2	17526531
Pubmed	Exome sequencing reveals NAA15 and PUF60 as candidate genes associated with intellectual disability.	NAA15 PUF60	4.94e-05	2	245	2	28990276
Pubmed	DNA topoisomerase II distribution in mouse preimplantation embryos.	TOP2A TOP2B	4.94e-05	2	245	2	11835579
Pubmed	The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation.	U2AF1L4 U2AF1	4.94e-05	2	245	2	32116123
Pubmed	Metastatic Prostate Cancers with BRCA2 versus ATM Mutations Exhibit Divergent Molecular Features and Clinical Outcomes.	BRCA2 ATM	4.94e-05	2	245	2	37126020
Pubmed	Serine 707 of APPL1 is Critical for the Synaptic NMDA Receptor-Mediated Akt Phosphorylation Signaling Pathway.	DLG4 APPL1	4.94e-05	2	245	2	27300007
Pubmed	Analysis of epidermal-type transglutaminase (transglutaminase 3) in human stratified epithelia and cultured keratinocytes using monoclonal antibodies.	FLG TGM3	4.94e-05	2	245	2	12850301
Pubmed	Using a biochemical approach to identify the primary dimerization regions in human DNA topoisomerase IIalpha.	TOP2A TOP2B	4.94e-05	2	245	2	10473615
Pubmed	Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain.	TOP2A TOP2B	4.94e-05	2	245	2	9224616
Pubmed	DNA damage response during chromatin remodeling in elongating spermatids of mice.	TOP2A TOP2B	4.94e-05	2	245	2	18032420
Pubmed	Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants.	TOP2A TOP2B	4.94e-05	2	245	2	22111588
Pubmed	The effect of dietary carbohydrate restriction and aerobic exercise on retinol binding protein 4 (RBP4) and fatty acid binding protein 5 (FABP5) in middle-aged men with metabolic syndrome.	FABP5 RBP4	4.94e-05	2	245	2	36373560
Pubmed	Phosphoinositide 3-kinase (PI3K(p110alpha)) directly regulates key components of the Z-disc and cardiac structure.	PIK3CA ITGB1BP2	4.94e-05	2	245	2	21757757
Interaction	TRIM28 interactions	UTP6 MCMBP ZNF527 ZNF678 CNPY2 ZNF626 U2AF1 NOP9 BRCA2 ZNF81 ZNF468 ZNF107 DYNC1H1 ZNF681 ZNF567 ZNF555 L3MBTL2 RBM45 POLE ZNF485 FARSB BRCC3 NUP214 ZNF416 ZNF284 ZNF675 CDC37 NBAS ZNF28 ZNF92 ZFP1 ZNF888 ATM SCRIB ZNF30 ZNF90 TOP2A TOP2B	3.46e-06	1474	236	38	int:TRIM28
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF626 ZNF681 ZNF729 ZNF675 ZNF43 ZNF66 ZNF90 ZNF99	3.35e-07	122	245	8	chr19p12
Cytoband	19p12	ZNF626 ZNF681 ZNF729 ZNF675 ZNF66 ZNF90 ZNF99	5.80e-07	90	245	7	19p12
Cytoband	8q24.3	GFUS ZNF623 PUF60 ADCK5 SCRIB	3.65e-04	113	245	5	8q24.3
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF141 ZNF143 ZNF527 ZNF586 ZNF678 ZNF177 ZNF626 ZNF623 ZNF891 ZBTB24 ZNF551 ZNF506 ZNF770 ZNF81 ZNF468 ZNF107 ZNF426 ZNF681 ZNF729 ZNF502 ZNF567 ZNF555 ZNF560 GLIS3 ZNF485 ZNF510 ZNF416 ZNF284 ZNF675 ZNF28 ZNF43 ZNF92 ZFP1 ZNF667 ZNF888 ZNF525 ZNF30 ZNF90 ZNF99 GLIS1	1.59e-19	718	177	40	28
GeneFamily	PDZ domain containing	MAGI1 FRMPD4 PARD6G ARHGEF11 DLG4 RGS12 GIPC3 SNTG2 SCRIB	1.90e-05	152	177	9	1220
GeneFamily	N(alpha)-acetyltransferase subunits\|GCN5 related N-acetyltransferases	NAA25 NAA16 NAA15	1.90e-04	12	177	3	660
GeneFamily	Dyneins, cytoplasmic	DYNC1H1 DYNC2H1 DYNC2LI1	2.45e-04	13	177	3	538
GeneFamily	RNA binding motif containing	U2AF1L4 U2AF1 CELF6 ENOX1 RBM45 PUF60 CELF2 ELAVL3	1.21e-03	213	177	8	725
GeneFamily	Topoisomerases	TOP2A TOP2B	1.39e-03	6	177	2	1050
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000	SMG1 RGMB BCAS3 PARD6G CHIC1 NRP2 JAK1 NEK1 HERC2 CPLANE1 FERMT2 GULP1 WASL NUP214 HIPK3 GTF2I ERCC6L2	9.35e-07	385	227	17	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	SMG1 RGMB BCAS3 PARD6G CHIC1 SLITRK1 NRP2 JAK1 NEK1 AFP HERC2 CPLANE1 FERMT2 GULP1 PAPPA2 WASL NUP214 HIPK3 GTF2I ERCC6L2 ELAVL3 TCFL5 LGI1	2.44e-05	818	227	23	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	NAA25 SAMD9L BRCA2 MICAL3 DDX60L ZNF107 LY86 RUBCNL OAS1 IDH3A ZNF92	6.22e-09	183	245	11	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	ZNF678 DAG1 CNOT6 ZNF770 CPLANE1 DYNC1H1 GNL3L KIF21A APPL1 SMCR8	1.25e-07	193	245	10	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Control-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	PARD6G GFUS FABP5 NRP2 MICAL3 GLIS3 PKHD1L1 SNTG2 PLCE1	1.47e-06	196	245	9	e0cf617b0f5d9c3c19574f587a3d0ccbf93d8ca4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 FRMPD4 INPP4A WDR72 GPRC6A CELF2 PLCE1 DNAH11	1.52e-06	146	245	8	ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 SAMD9L ANKRD12 DDX60L DYNC1H1 OAS1 CELF2 ANKRD11 ATM	1.73e-06	200	245	9	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-NK_CD56bright\|ICU-NoSEP / Disease, condition lineage and cell class	NBPF12 DIS3L DNAH14 JAK1 MICAL3 FHL1 ZNF485 NSUN6 DOCK7	1.73e-06	200	245	9	c2df917900872453ea17a39928e39d071a6d3339
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SERPINB9 POLE SLC26A9 BIRC5 GALNT12 KLRK1 ATM TOP2A	4.94e-06	171	245	8	1eebd7138c3b20ddc1104f21615f9df0e776bbe6
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MATN1 NRP2 SERPINB9 NOS2 ZNF560 GLIS3 SLC26A9 PKHD1L1	6.36e-06	177	245	8	76f5df101c693e5fa61554244d877fc8169ee66f
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAGI1 PARD6G NRP2 SERPINB9 NOS2 SLC26A9 PKHD1L1 SNTG2	6.91e-06	179	245	8	1c0c0647a111f691dae55f4ed8c51006059ce020
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CAPN8 NOS2 WDR72 TCN1 OAS1 GALNT12 MORC4 LGI1	8.12e-06	183	245	8	2dde2fb48e7d31271c2f6b1dd74b2ab0b2cb520c
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_B-GC_B_(I)\|lymph-node_spleen / Manually curated celltypes from each tissue	FABP5 DIAPH3 RASGRF1 FARSB BIRC5 TEX15 PAICS TOP2A	8.45e-06	184	245	8	057c6c2f570914fa4af84682589a86b61547d6c9
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TCTN3 ZNF177 PARD6G GFUS NAV1 ENOX1 PKHD1L1 HCRTR1	9.15e-06	186	245	8	9579180db2a0bf3f043b4d169f9a08cdc45b459a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 FRMPD4 NRP2 ZNF506 WDR72 GPRC6A CELF2	1.05e-05	136	245	7	7cd22169fb71c6caf9feb203ad98be8480a54fba
ToppCell	NS-critical-d_0-4-Epithelial-Basal\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DLG4 ZNF426 ZNF502 ZNF485 BIRC5 ZFP1 ZNF525 ZNF90	1.20e-05	193	245	8	1affb4c2e21712bde0d36ab736411fe36642cc6d
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	SMG1 SAMD9L ANKRD12 DDX60L OAS1 CNOT6L CSNK1D DUSP10	1.20e-05	193	245	8	7256a5a491536c525b31ae96d47ab5c6303cb73a
ToppCell	PCW_07-8.5\|World / Celltypes from embryonic and fetal-stage human lung	MAGI1 ZBTB24 DNAH14 NRP2 BRCA2 DIAPH3 ZNF43 TOP2A	1.24e-05	194	245	8	5759c83308df017f1faae248e9b85388e25254f0
ToppCell	Macroglial-Astrocytes-SLC14A1---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAP3K5 SPON1 GLIS3 COL5A3 CELF2 DOCK7 NBPF10 LGI1	1.55e-05	200	245	8	d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCell	Macroglial-Astrocytes-SLC14A1----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAP3K5 SPON1 GLIS3 COL5A3 CELF2 DOCK7 NBPF10 LGI1	1.55e-05	200	245	8	f861509b54185d89931db64da1b9d81986cc7938
ToppCell	Macroglial-Astrocytes-SLC14A1\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAP3K5 SPON1 GLIS3 COL5A3 CELF2 DOCK7 NBPF10 LGI1	1.55e-05	200	245	8	16f468217427921fa18c6d078ffa990eb019b257
ToppCell	Macroglial-Astrocytes-SLC14A1--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAP3K5 SPON1 GLIS3 COL5A3 CELF2 DOCK7 NBPF10 LGI1	1.55e-05	200	245	8	0442894c39eec69850c090957a5dc7bcecd21e04
ToppCell	Macroglial-Astrocytes-SLC14A1-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAP3K5 SPON1 GLIS3 COL5A3 CELF2 DOCK7 NBPF10 LGI1	1.55e-05	200	245	8	01819446deeab9054f5cfe889d53bb49d137dbc0
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8\|TCGA-Bladder / Sample_Type by Project: Shred V9	ZNF107 ZNF681 ZNF675 ZNF43 ZNF92 ZNF66 TOP2B	1.98e-05	150	245	7	1aa9320d97ff10994ea024751790524fe133aba9
ToppCell	368C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MATN1 WDR24 POLE PLXNC1 ITGB1BP2 SLIT3 TOP2A	2.55e-05	156	245	7	4877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell	356C-Myeloid-Dendritic-pDC\|356C / Donor, Lineage, Cell class and subclass (all cells)	SMG1 MATN1 ZNF891 WDR24 FLNB RUBCNL IDH3A	2.55e-05	156	245	7	d9d87368e43b24952e70f31f38425e15b716ff5b
ToppCell	368C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MATN1 WDR24 POLE PLXNC1 ITGB1BP2 SLIT3 TOP2A	2.55e-05	156	245	7	1d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SMG1 USP9Y ZNF506 ANKRD12 CNOT6L CELF2 ATM	3.24e-05	162	245	7	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BRCA2 DIAPH3 SPINK5 PAK5 SLC26A9 TEX15 MORC4	3.79e-05	166	245	7	575c325db88d6909cdf0d5e664bd9098b89d4401
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	INPP4A USP9Y CAPN8 RHOBTB2 MICAL3 RASGRF1 SMCR8	3.94e-05	167	245	7	dbd2b9f2f4ba7be5fdf8318094e6b078cb1d1c43
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PKHD1 MICAL3 WDR72 GLIS3 SLIT3 MAP3K21 PLCE1	4.09e-05	168	245	7	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FANCD2OS BRCA2 DIAPH3 POLE BIRC5 TEX15 TOP2A	4.25e-05	169	245	7	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 SPINK5 CELF6 RNF17 PKHD1L1 CNGB3 DNAH11	4.25e-05	169	245	7	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAK6 BRCA2 LY86 APBB1IP BIRC5 CELF2 TOP2A	4.58e-05	171	245	7	55c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CCDC168 BRCA2 RUBCNL GLIS3 GPRC6A NBPF10 KDM7A	4.93e-05	173	245	7	8ac2e9d39c0f76e674f8bd59d1da246bab4867c8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 FRMPD4 NRP2 WDR72 GPRC6A CELF2 PLCE1	5.49e-05	176	245	7	6c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 FRMPD4 MAP3K5 WDR72 GPRC6A CELF2 DNAH11	5.90e-05	178	245	7	51d2188406f04329311b2efd1108fc36617a860e
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SWAP70 SPON1 MICAL3 ZNF107 RUBCNL ZNF92 ZNF667	5.90e-05	178	245	7	5d41fede13c8e64b6fdaf2155f1eb72bcfc32fdb
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-B_memory-0\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SWAP70 NRP2 MBD4 LY86 RASGRF1 RUBCNL PKHD1L1	6.11e-05	179	245	7	fce1ba53815145f6248d4e90aedca3dad84e33e4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 FRMPD4 INPP4A WDR72 GPRC6A CELF2 DNAH11	6.33e-05	180	245	7	cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MAGI1 FRMPD4 ZNF177 COL12A1 RBP4 COL5A3 ATP1B4	6.55e-05	181	245	7	19103221c3a5a16b16378348004b2c50caee4f01
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MAGI1 FRMPD4 ZNF177 COL12A1 RBP4 COL5A3 ATP1B4	6.55e-05	181	245	7	47dce04db3392333eb2f7b9b24c32e6740d2d02f
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2\|TCGA-Skin / Sample_Type by Project: Shred V9	DYNC1H1 RASGRF1 EPG5 PLXNC1 DOCK7 CTH DUSP10	6.55e-05	181	245	7	9d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAGI1 PARD6G NRP2 SERPINB9 GLIS3 PKHD1L1 SNTG2	7.02e-05	183	245	7	764ea07621f77fbd13a877aed5806ae2b3dfb43e
ToppCell	3'_v3-blood-Lymphocytic_B-Memory_B_cells\|blood / Manually curated celltypes from each tissue	SWAP70 RHOBTB2 MICAL3 LY86 RASGRF1 RUBCNL PKHD1L1	7.02e-05	183	245	7	e3a418b745d7f040adf47be9e1043b945cae47ed
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 CAPN8 PKHD1 COL12A1 PKHD1L1 PLCE1 DNAH11	7.26e-05	184	245	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 CAPN8 PKHD1 COL12A1 PKHD1L1 PLCE1 DNAH11	7.26e-05	184	245	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF21A RUBCNL BIRC5 ODC1 ELAVL3 CTH HCRTR1	7.26e-05	184	245	7	7712f2e1fae5cdde2d4e355b860dc8536b28e4f6
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 CAPN8 PKHD1 COL12A1 PKHD1L1 PLCE1 DNAH11	7.26e-05	184	245	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAGI1 PARD6G FABP5 NRP2 SERPINB9 PKHD1L1 SNTG2	7.26e-05	184	245	7	3b0389c3a5a16697de860e98ebc48ed39ede646f
ToppCell	CV-Healthy-7\|Healthy / Virus stimulation, Condition and Cluster	DAG1 MICAL3 ZNF681 DYNC2LI1 ZFP1 POFUT1 SMCR8	7.52e-05	185	245	7	1979d189c204f4c2893e3170a514ee7d5523406c
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T\|lymph-node_spleen / Manually curated celltypes from each tissue	ZNF177 U2AF1 DIAPH3 BIRC5 WRAP53 RGS12 TOP2A	7.77e-05	186	245	7	17eec1efad1f5e9ced1eb6bc9eb5dd7ded789c61
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	FHL1 COL12A1 ENOX1 COL5A3 SLIT3 PAM PLCE1	7.77e-05	186	245	7	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	10x5'-GI_small-bowel-Lymphocytic_B-GC_B_(I)\|GI_small-bowel / Manually curated celltypes from each tissue	SWAP70 USP9Y DIAPH3 RASGRF1 RUBCNL BIRC5 TOP2A	8.04e-05	187	245	7	a92cade2a835f5fce8de1e14650af8cdd818c296
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAK6 BRCA2 DIAPH3 ZNF729 BIRC5 ZNF43 TOP2A	8.04e-05	187	245	7	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	COVID-19-kidney-CD-IC-B\|kidney / Disease (COVID-19 only), tissue and cell type	MAGI1 FRMPD4 INPP4A WDR72 GPRC6A CELF2 DNAH11	8.04e-05	187	245	7	ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SWAP70 MICAL3 LY86 RASGRF1 RUBCNL ODC1 PKHD1L1	8.31e-05	188	245	7	6f53bcd4caab2fc961af799039ea5c3ddae56781
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	SMG1 U2AF1 ANKRD12 DYNC1H1 EPG5 CELF2 ANKRD11	8.31e-05	188	245	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	MS-CD8-CD4_Treg\|MS / Condition, Cell_class and T cell subcluster	ARMC2 BRCA2 FERMT2 WDR24 FARSB ZNF675 ZNF30	8.31e-05	188	245	7	2f0e2c7d79ee2d69a5d908c0247dc950c056c30a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	INPP4A NAA16 FLNB GALNT12 KLRK1 ERCC6L2 ATM	8.59e-05	189	245	7	e9df7ecd36bee1fedce23bb188c68a94fa60462c
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPON1 PKHD1 RBP4 ODC1 DYNC2LI1 SLIT3 DNAH11	8.88e-05	190	245	7	b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCell	PBMC-Severe-cDC_12\|Severe / Compartment, Disease Groups and Clusters	MCMBP BRCA2 RBP4 TOPBP1 BIRC5 PAICS TOP2A	8.88e-05	190	245	7	84ee185939bdefb10705b621a70da27701eadcee
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 MTMR10 DNAH14 PKHD1 DIAPH3 GLIS3 DYNC2LI1	9.18e-05	191	245	7	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 DNAH14 ITPR3 PKHD1 RASGRF1 SLC26A9 MAP3K21	9.48e-05	192	245	7	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	COVID-19-Epithelial-AT2,_AT1_cells\|Epithelial / Condition, Lineage and Cell class	ITPR3 CAPN8 RHOBTB2 FERMT2 ODC1 CELF2 PAM	9.79e-05	193	245	7	fdebd4a13c189e20638c7d5b351327c33dd36380
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-11\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SWAP70 SPON1 MICAL3 RUBCNL PKHD1L1 ZNF92 ZNF667	9.79e-05	193	245	7	cf4ba50aa4a00d1ba22fc7626d49a4104377d5d9
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LNP1 SPON1 PKHD1 RBP4 ODC1 DYNC2LI1 DNAH11	9.79e-05	193	245	7	ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCell	368C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RAB28 BRCA2 ZNF468 CPLANE1 COL5A3 SLIT3 ZNF525	9.79e-05	193	245	7	5f5904cec8b2967154ef2eab3c48f51df53aca4a
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BRCA2 MED12L DIAPH3 TCN1 POLE BIRC5 TOP2A	9.79e-05	193	245	7	ccab6a0c76f574ef7e1d6d5f1e620376daf21bbf
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRCA2 DIAPH3 POLE BIRC5 TEX15 TOP2A	9.84e-05	134	245	6	4d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BRCA2 MED12L DIAPH3 TCN1 POLE BIRC5 TOP2A	1.01e-04	194	245	7	23318a1b55895b5166c6151f488a94a09b4627ff
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITPR3 CAPN8 JAK1 RHOBTB2 WASL SLC26A9 ZNF90	1.01e-04	194	245	7	54975e663ed4414b99b3c9a1aa6335613946470f
ToppCell	IPF-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	PARD6G FABP5 NRP2 FHL1 GLIS3 PKHD1L1 PLCE1	1.04e-04	195	245	7	de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCell	COPD-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	PARD6G GFUS FABP5 NRP2 GLIS3 PKHD1L1 PLCE1	1.04e-04	195	245	7	e91ce548ae7224661ee5d2f2639794a5f69798ee
ToppCell	Sepsis-Bac-SEP-Lymphocyte-B-B_intermediate\|Bac-SEP / Disease, condition lineage and cell class	SWAP70 ITPR3 RASGRF1 PKHD1L1 GIPC3 ZNF667 PLCE1	1.08e-04	196	245	7	1611920211beb1a3691e3853e0314792a74279a0
ToppCell	(7)_Epithelial-B_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	FABP5 ITPR3 CAPN8 RHOBTB2 SPINK5 RASGRF1 SLC26A9	1.08e-04	196	245	7	345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	RGMB PARD6G FERMT2 COL12A1 DYNC2H1 RBP4 COL5A3	1.11e-04	197	245	7	c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCell	myeloid-pro-pDC\|World / Lineage and Cell class	FABP5 BRCA2 FHL1 FLNB BIRC5 IDH3A TOP2A	1.11e-04	197	245	7	8918ee006b16f6b86ed33ce1dd5c0f01f51f88f5
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	FABP5 ITPR3 CAPN8 RHOBTB2 SPINK5 RASGRF1 SLC26A9	1.11e-04	197	245	7	f98720cab066579fdac3ba24fb6fe4c5759dae4e
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	FABP5 ITPR3 CAPN8 RHOBTB2 SPINK5 RASGRF1 SLC26A9	1.11e-04	197	245	7	f3ca63c7902d7530a29a85eb54f69b303031d150
ToppCell	Transverse-Dendritic_cell-Lymphoid_DC\|Dendritic_cell / Region, Cell class and subclass	USP9Y MTMR10 NRP2 ENOX1 KIF21A ZNF675 SMCR8	1.11e-04	197	245	7	8545baf923ddf84c5ce9414a36d810603be52401
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	SMG1 SAMD9L ANKRD12 DDX60L OAS1 CSNK1D ANKRD11	1.11e-04	197	245	7	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 USP9Y NLRC5 ANKRD12 CELF2 ANKRD11 ATM	1.18e-04	199	245	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	COVID-19-lung\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRP2 CAPN8 SAMD9L NLRC5 APBB1IP CELF2 PLXNC1	1.18e-04	199	245	7	155b03b859157013e9142e9248551369127d9204
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-CARM1P1--L3-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CCDC168 BRCA2 RUBCNL GLIS3 GPRC6A NBPF10 KDM7A	1.22e-04	200	245	7	47791c93d03ee17c1ce17e27f075be4fc6f2590e
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	RGMB NAV1 KIF21A HECTD4 GTF2I CSNK1E ELAVL3	1.22e-04	200	245	7	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-CARM1P1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CCDC168 BRCA2 RUBCNL GLIS3 GPRC6A NBPF10 KDM7A	1.22e-04	200	245	7	f75d95376a340d467c4392b872b2a2dbdd184556
ToppCell	Macroglial-Astrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAP3K5 SPON1 GLIS3 COL5A3 CELF2 DOCK7 LGI1	1.22e-04	200	245	7	941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 JAK1 SAMD9L KIF21A KLRK1 CNOT6L ATM	1.22e-04	200	245	7	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	Severe-T/NK_proliferative\|Severe / Disease group and Cell class	FABP5 BRCA2 DIAPH3 TOPBP1 BIRC5 PAICS TOP2A	1.22e-04	200	245	7	4723613a9f56bff422fc98722128d57b6adf3c5d
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-CARM1P1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CCDC168 BRCA2 RUBCNL GLIS3 GPRC6A NBPF10 KDM7A	1.22e-04	200	245	7	fae26560ba3b0b638b6bcf92f05330824b31d21b
Disease	asphyxiating thoracic dystrophy (is_implicated_in)	NEK1 DYNC2H1 DYNC2LI1	1.62e-05	7	231	3	DOID:0050592 (is_implicated_in)
Disease	Polydactyly	TCTN3 ZNF141 NEK1 PIK3CA CPLANE1 DYNC2H1 DYNC2LI1	3.93e-05	117	231	7	C0152427
Disease	Short rib-polydactyly syndrome, Majewski type	NEK1 DYNC2H1	6.10e-05	2	231	2	cv:CN305384
Disease	Statin causing adverse effect in therapeutic use	RYR1 SLCO1B1	6.10e-05	2	231	2	cv:C0570410
Disease	Statin-induced myopathy	RYR1 SLCO1B1	6.10e-05	2	231	2	cv:CN181199
Disease	B cell deficiency (implicated_via_orthology)	TOP2A TOP2B	6.10e-05	2	231	2	DOID:2115 (implicated_via_orthology)
Disease	cystatin C measurement	BCAS3 NAA25 PKHD1 PYGB WDR72 HECTD4 SLCO1B1 NBAS TGM3 ANKRD11 CTH GLIS1	8.63e-05	402	231	12	EFO_0004617
Disease	Stomach Neoplasms	ZNF177 CNPY2 PIK3CA AFP POLE RBP4 BIRC5 NBAS ATM PLCE1	1.27e-04	297	231	10	C0038356
Disease	Short Rib-Polydactyly Syndrome	NEK1 DYNC2H1 DYNC2LI1	1.28e-04	13	231	3	C0036996
Disease	Malignant neoplasm of stomach	ZNF177 CNPY2 PIK3CA AFP POLE RBP4 BIRC5 NBAS ATM PLCE1	1.38e-04	300	231	10	C0024623
Disease	Majewski Syndrome	NEK1 DYNC2H1 DYNC2LI1	1.62e-04	14	231	3	C0024507
Disease	Saldino-Noonan Syndrome	NEK1 DYNC2H1 DYNC2LI1	1.62e-04	14	231	3	C0036069
Disease	endometrial cancer (is_implicated_in)	JAK1 BRCA2 POLE ATM	1.77e-04	36	231	4	DOID:1380 (is_implicated_in)
Disease	squamous cell carcinoma	BRCA2 HERC2 TGM3 ANKRD11 DNAH11	1.83e-04	67	231	5	EFO_0000707
Disease	FEV/FEC ratio	UTP6 BCAS3 ARMC2 NRP2 CROCC2 NAV1 MICAL3 LY86 NAA15 ENOX1 GLIS3 SLC26A9 GALNT12 FAM227B SLCO1B1 GTF2I ERCC6L2 ANKRD11 KDM7A POFUT1 TOP2B HCRTR1	2.81e-04	1228	231	22	EFO_0004713
Disease	Carcinoma in situ of stomach	PIK3CA POLE ATM	2.97e-04	17	231	3	C0154060
Disease	Benign neoplasm of stomach	PIK3CA POLE ATM	2.97e-04	17	231	3	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	PIK3CA POLE ATM	2.97e-04	17	231	3	C0496905
Disease	hepatitis (biomarker_via_orthology)	AFP NOS2	3.62e-04	4	231	2	DOID:2237 (biomarker_via_orthology)
Disease	uveal melanoma (is_implicated_in)	BRCA2 MBD4	3.62e-04	4	231	2	DOID:6039 (is_implicated_in)
Disease	Malignant neoplasm of prostate	RGMB DAG1 PAK6 JAK1 U2AF1 BRCA2 PIK3CA HSD17B3 SPINK5 BIRC5 COL5A3 CELF2 ATM TOP2A	3.88e-04	616	231	14	C0376358
Disease	Prostatic Neoplasms	RGMB DAG1 PAK6 JAK1 U2AF1 BRCA2 PIK3CA HSD17B3 SPINK5 BIRC5 COL5A3 CELF2 ATM TOP2A	3.88e-04	616	231	14	C0033578
Disease	colorectal cancer (is_implicated_in)	JAK1 PIK3CA POLE GALNT12 WRAP53 ATM	3.92e-04	121	231	6	DOID:9256 (is_implicated_in)
Disease	Hereditary Diffuse Gastric Cancer	ZNF177 CNPY2 PIK3CA AFP RBP4 BIRC5 NBAS ATM PLCE1	5.38e-04	293	231	9	C1708349
Disease	Stomach Carcinoma	PIK3CA POLE ATM	5.68e-04	21	231	3	C0699791
Disease	BREAST CANCER	BRCA2 PIK3CA ATM	5.68e-04	21	231	3	114480
Disease	atopy	PAK6 PAK5	6.01e-04	5	231	2	EFO_0002686
Disease	peak expiratory flow	UTP6 ARMC2 MICAL3 LY86 PAPPA2 GLIS3 SLC26A9 GALNT12 FAM227B DYNC2LI1 ERCC6L2 HCRTR1	6.05e-04	498	231	12	EFO_0009718
Disease	descending aortic diameter	NAV1 FHL1 PAPPA2 FLNB PLCE1	6.51e-04	88	231	5	EFO_0021788
Disease	renal system measurement, blood urea nitrogen measurement	BCAS3 WDR72 HECTD4	6.53e-04	22	231	3	EFO_0004741, EFO_0004742
Disease	Immunologic Deficiency Syndromes	EPG5 NBAS ATM	7.47e-04	23	231	3	C0021051
Disease	carnosine measurement	ZNF681 ZNF675 HCRTR1	8.49e-04	24	231	3	EFO_0010470
Disease	Malignant neoplasm of breast	NOP9 NAA25 BRCA2 PIK3CA AFP NLRC5 HERC2 NOS2 FLNB DYNC2H1 BIRC5 NUP214 SLCO1B1 EPG5 NSUN6 CSNK1D APPL1 ATM TOP2A	8.52e-04	1074	231	19	C0006142
Disease	Intellectual Disability	FRMPD4 INPP4A ZBTB24 RHOBTB2 MED12L DLG4 DYNC1H1 NAA15 PUF60 FARSB ODC1	8.57e-04	447	231	11	C3714756
Disease	glycocholenate sulfate measurement	ADCK5 SLCO1B1	8.97e-04	6	231	2	EFO_0800276
Disease	Chronic Lymphocytic Leukemia	U2AF1 PIK3CA TOPBP1 ATM	9.13e-04	55	231	4	C0023434
Disease	ovarian cancer (is_implicated_in)	JAK1 BRCA2 PIK3CA WRAP53	9.77e-04	56	231	4	DOID:2394 (is_implicated_in)
Disease	Adenoid Cystic Carcinoma	MAGI1 PIK3CA PYGB ATM TOP2A	1.16e-03	100	231	5	C0010606
Disease	Breast Carcinoma	NOP9 BRCA2 PIK3CA AFP HERC2 NOS2 DYNC2H1 BIRC5 SLCO1B1 NSUN6 ATM TOP2A	1.18e-03	538	231	12	C0678222
Disease	Malignant tumor of breast	BRCA2 PIK3CA ATM	1.21e-03	27	231	3	cv:C0006142
Disease	Breast neoplasm	BRCA2 PIK3CA ATM	1.21e-03	27	231	3	cv:C1458155
Disease	Familial cancer of breast	BRCA2 PIK3CA ATM	1.21e-03	27	231	3	cv:C0346153
Disease	lissencephaly (implicated_via_orthology)	DAG1 NOS2 DYNC1H1	1.21e-03	27	231	3	DOID:0050453 (implicated_via_orthology)
Disease	syndromic X-linked intellectual disability Najm type (implicated_via_orthology)	CSNK1D CSNK1E	1.25e-03	7	231	2	DOID:0060807 (implicated_via_orthology)
Disease	OROFACIODIGITAL SYNDROME VI	TCTN3 CPLANE1	1.25e-03	7	231	2	C2745997
Disease	disease recurrence, response to allogeneic hematopoietic stem cell transplant, donor genotype effect measurement	PAK6 PAK5	1.25e-03	7	231	2	EFO_0004952, EFO_0007044, EFO_0007892
Disease	disease of cellular proliferation (implicated_via_orthology)	JAK1 ATM	1.25e-03	7	231	2	DOID:14566 (implicated_via_orthology)
Disease	infertility (implicated_via_orthology)	BRCA2 ATM	1.25e-03	7	231	2	DOID:5223 (implicated_via_orthology)
Disease	Angle Closure Glaucoma	FERMT2 GLIS3	1.25e-03	7	231	2	C0017605
Disease	primary biliary cholangitis (biomarker_via_orthology)	DAG1 NOS2 IL4	1.34e-03	28	231	3	DOID:12236 (biomarker_via_orthology)
Disease	lifestyle measurement, depressive symptom measurement	RGMB DIS3L COL12A1 ENOX1 MAP3K21	1.44e-03	105	231	5	EFO_0007006, EFO_0010724
Disease	tuberculosis	FRMPD4 SPON1 DCUN1D5 DYNC2H1 KIF21A RGS12 CNOT6L	1.63e-03	216	231	7	MONDO_0018076
Disease	Breast Cancer, Familial	BRCA2 PIK3CA ATM	1.64e-03	30	231	3	C0346153
Disease	Williams Syndrome	DLG4 GTF2I	1.66e-03	8	231	2	C0175702
Disease	benign neoplasm (implicated_via_orthology)	DLG4 SCRIB	1.66e-03	8	231	2	DOID:0060072 (implicated_via_orthology)
Disease	beta-Ala-His dipeptidase measurement	ZNF681 ZNF675	1.66e-03	8	231	2	EFO_0008033
Disease	Ciliopathies	NEK1 PKHD1 CPLANE1 DYNC2H1 DNAH11	1.77e-03	110	231	5	C4277690
Disease	tetradecanedioate measurement	SLCO1B1 LGI1	2.12e-03	9	231	2	EFO_0021057
Disease	urea measurement	BCAS3 TGM3	2.63e-03	10	231	2	EFO_0011005
Disease	carboxypeptidase B2 measurement	ZC3H13 SNTG2	2.63e-03	10	231	2	EFO_0008069
Disease	lymphocyte count	TCTN3 AKAP17A BCAS3 ARHGEF11 JAK1 SERPINB9 MED12L NLRC5 MICAL3 DDX60L APBB1IP FLNB PCDHGB5 HECTD4 GLIS3 CDC37 ZFP1 ERCC6L2 ANKRD11 KYAT3 ATM PLCE1	2.71e-03	1464	231	22	EFO_0004587
Disease	intellectual disability (implicated_via_orthology)	CAPN8 NAA16 NAA15 DYRK1B	2.88e-03	75	231	4	DOID:1059 (implicated_via_orthology)
Disease	Mammary Carcinoma, Human	NOP9 BRCA2 PIK3CA AFP NOS2 DYNC2H1 BIRC5 SLCO1B1 NSUN6 ATM TOP2A	3.02e-03	525	231	11	C4704874
Disease	Mammary Neoplasms, Human	NOP9 BRCA2 PIK3CA AFP NOS2 DYNC2H1 BIRC5 SLCO1B1 NSUN6 ATM TOP2A	3.02e-03	525	231	11	C1257931
Disease	Mammary Neoplasms	NOP9 BRCA2 PIK3CA AFP NOS2 DYNC2H1 BIRC5 SLCO1B1 NSUN6 ATM TOP2A	3.11e-03	527	231	11	C1458155
Disease	Disproportionate short stature	TCTN3 NEK1 FLNB DYNC2H1	3.17e-03	77	231	4	C0878659
Disease	smoking status measurement, forced expiratory volume	PKHD1 ZNF675	3.20e-03	11	231	2	EFO_0004314, EFO_0006527
Disease	primary angle closure glaucoma	FERMT2 GLIS3	3.20e-03	11	231	2	EFO_1001506
Disease	Jeune thoracic dystrophy	DYNC2H1 DYNC2LI1	3.20e-03	11	231	2	C0265275
Disease	autosomal recessive polycystic kidney disease (biomarker_via_orthology)	PIK3CA PKHD1	3.20e-03	11	231	2	DOID:0110861 (biomarker_via_orthology)
Disease	kidney cancer (implicated_via_orthology)	POLE SCRIB	3.20e-03	11	231	2	DOID:263 (implicated_via_orthology)
Disease	tea consumption measurement	TUBG2 NAA25 PKHD1 HECTD4 XK	3.53e-03	129	231	5	EFO_0010091
Disease	platelet crit	VPS11 SWAP70 BCAS3 DAG1 ARHGEF11 JAK1 NAA25 SERPINB9 SPSB3 WDR24 WASL SLCO1B1 EPG5 TGM3 KDM7A PLCE1	3.57e-03	952	231	16	EFO_0007985
Disease	acute myeloid leukemia (implicated_via_orthology)	TOP2A TOP2B	3.82e-03	12	231	2	DOID:9119 (implicated_via_orthology)
Disease	forced expiratory volume	RGMB BCAS3 ARMC2 ZBTB24 CROCC2 MICAL3 MBD4 GLIS3 GALNT12 FAM227B SLCO1B1 ERCC6L2 POFUT1 TOP2B	3.93e-03	789	231	14	EFO_0004314
Disease	Neoplasm of uncertain or unknown behavior of breast	BRCA2 PIK3CA HERC2	4.05e-03	41	231	3	C0496956
Disease	Breast adenocarcinoma	BRCA2 PIK3CA HERC2	4.05e-03	41	231	3	C0858252
Disease	birth weight, parental genotype effect measurement	ARMC2 PAPPA2 GLIS3 GPRC6A CELF2 PLCE1	4.15e-03	192	231	6	EFO_0004344, EFO_0005939
Disease	Alzheimer's disease (is_marker_for)	DLG4 HSD17B3 NOS2 DYNC1H1 CSNK1D CSNK1E ATM	4.28e-03	257	231	7	DOID:10652 (is_marker_for)
Disease	aortic stenosis, aortic valve calcification	NAV1 FLNB SNTG2	4.34e-03	42	231	3	EFO_0000266, EFO_0005239
Disease	xanthine measurement	MATN1 CELF2	4.50e-03	13	231	2	EFO_0010548
Disease	Autism Spectrum Disorders	DLG4 GTF2I ANKRD11 SNTG2	4.52e-03	85	231	4	C1510586
Disease	Glioma	BRCA2 PIK3CA ATM TOP2A	4.91e-03	87	231	4	C0017638
Disease	psoriasis (is_marker_for)	FABP5 RBP4 IL4	4.95e-03	44	231	3	DOID:8893 (is_marker_for)
Disease	smoking status measurement, chronic obstructive pulmonary disease	ARMC2 MICAL3 GLIS3 GALNT12	5.11e-03	88	231	4	EFO_0000341, EFO_0006527
Disease	Malformations of Cortical Development	PIK3CA DYNC1H1	5.22e-03	14	231	2	C1955869
Disease	beta-amyloid 1-42 measurement, cerebrospinal fluid biomarker measurement	HSD17B3 LGI1	5.22e-03	14	231	2	EFO_0004670, EFO_0006794
Disease	Cortical Dysplasia	PIK3CA DYNC1H1	5.22e-03	14	231	2	C0431380
Disease	cancer (implicated_via_orthology)	BRCA2 DLG4 POLE ATM SCRIB TOP2A TOP2B	5.37e-03	268	231	7	DOID:162 (implicated_via_orthology)
Disease	creatinine measurement	GAPVD1 BCAS3 INPP4A RYR1 PKHD1 MBD4 WDR72 VIL1 GLIS3 FAM227B RGS12 PLXNC1 DYNC2LI1 DOCK7 ANKRD11 KYAT3	5.43e-03	995	231	16	EFO_0004518
Disease	Adenocarcinoma of lung (disorder)	NEK1 PIK3CA PAK5 CSNK1E ATM TOP2A	5.82e-03	206	231	6	C0152013
Disease	Williams-Beuren syndrome (implicated_via_orthology)	DLG4 GTF2I	5.99e-03	15	231	2	DOID:1928 (implicated_via_orthology)
Disease	periprosthetic osteolysis, disease progression measurement	MATN1 GLIS3	5.99e-03	15	231	2	EFO_0008336, EFO_0009761
Disease	hepcidin:transferrin saturation ratio	SLITRK1 ZNF551	5.99e-03	15	231	2	EFO_0007902
Disease	developmental disorder of mental health (implicated_via_orthology)	DLG4 NAA16 NAA15	6.69e-03	49	231	3	DOID:0060037 (implicated_via_orthology)
Disease	pancreatitis	HECTD4 MORC4	6.81e-03	16	231	2	EFO_0000278
Disease	Dermatitis	FLG IL4	6.81e-03	16	231	2	C0011603
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	NEK1 PKHD1	6.81e-03	16	231	2	DOID:0110861 (implicated_via_orthology)
Disease	Adenocarcinoma of large intestine	PIK3CA POLE PAK5 ATM	6.93e-03	96	231	4	C1319315
Disease	autism spectrum disorder (implicated_via_orthology)	NRP2 ITPR3 DLG4 NAA16 NAA15	7.03e-03	152	231	5	DOID:0060041 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSGCAFLSVKKQFEE	BIRC5	81	O15392
ETEKNIEGCSFTGFK	FAM227B	141	Q96M60
EAFFKVERGSPKSCF	EPG5	2071	Q9HCE0
IDKQTNLSKCFGFVS	CELF2	456	O95319
EVRFGKRSDKFCSSE	ANKRD11	466	Q6UB99
DCTSFSELVENFKKT	CATSPER3	316	Q86XQ3
GDKDVCTNIARIFSK	ARMC2	486	Q8NEN0
KTKTSRDLACFIQFE	APBB1IP	346	Q7Z5R6
EERLLKFSIGAKCNT	SPATA5	306	Q8NB90
VATDKRAFFIICTSK	ARHGEF11	1036	O15085
SEFGLKISFVDCSKI	CTH	126	P32929
LTASFEKATAEKVRC	DNAH11	3351	Q96DT5
GRIQCFKTDTKEFVR	PAM	706	P19021
KKTASAQEFARCLDS	GIPC3	271	Q8TF64
IRDFTTNKCKGFGFV	ELAVL3	316	Q14576
DKSSKRVLTADFCAG	ADCK5	306	Q3MIX3
KRTDIKFDGFNINTC	CAPN8	566	A6NHC0
VVFKERSDICKASAF	FLG	4006	P20930
CSEKTREEGNFRKSF	ANKRD12	511	Q6UB98
LTSAGEEKKIDRFFC	DIAPH3	311	Q9NSV4
LQEKIAAFDSCTFTK	BCAS3	201	Q9H6U6
KVFVDRATNQSKCFG	CELF6	426	Q96J87
DCTEKLQNKFDFLRS	DCUN1D5	116	Q9BTE7
KRSAIKIVDFGSSCQ	DYRK1B	251	Q9Y463
QFKRSFLKNCSGLED	ATP1B4	221	Q9UN42
TASKDCLFAIVGNKV	RAB20	101	Q9NX57
KTGDSVFLCFQKVAA	RAB28	161	P51157
KGIAFVKFARSSQAC	RBM45	66	Q8IUH3
LKTCRFANSALKEFE	RUBCNL	536	Q9H714
SIITKKTFSFNFCRE	OR9G1	156	Q8NH87
KTCVVQRFKTGAFSE	RAB43	31	Q86YS6
DFLKEFNNKTICDSS	JAK1	246	P23458
CGLERDKFDNKTVSF	ITPR3	2541	Q14573
RLNGVRFTSCKSAKD	INPP4A	886	Q96PE3
TFKAACETFDVRGKQ	NOS2	676	P35228
RIKLSDFGFCAQVSK	PAK5	581	Q9P286
GKVFSQKTICRFEAL	POU5F1B	176	Q06416
KDIAVFITDKISSFC	NOP9	266	Q86U38
IKSATRRQKAFGTCF	OR2G2	231	Q8NGZ5
KLSDFGFCAQISKDV	PAK6	541	Q9NQU5
DFFQKFGKVRSSVCS	EPM2A	316	O95278
VTQSEVFFGDKVDKC	KDM7A	321	Q6ZMT4
SKIEKFSESFERQLC	LNP1	106	A1A4G5
FDRFVQATTCKGTLK	MICAL3	16	Q7RTP6
KLSRKFQEAFCVVSD	MATN1	211	P21941
FGDLFSSACSKVKQT	MED12L	946	Q86YW9
DSCKEAVTFKAVRQG	MAGI1	91	Q96QZ7
IAEEFCLKTFSKFGS	NEK1	271	Q96PY6
FGFSVEKCSKQLKSN	LY86	51	O95711
RTVDFSEFLNIKGCT	ITGB1BP2	46	Q9UKP3
GKLICSNFKISFITD	MTMR10	66	Q9NXD2
VGTREAFFSKTKRFC	L3MBTL2	96	Q969R5
KVRCGSQFSIALTKD	HERC2	661	O95714
CAEIFKQRFSEENSK	SPINK5	261	Q9NQ38
CFQITSFDGKKSSIL	APPL1	341	Q9UKG1
SLGKFDKSCVAAFLD	GAPVD1	366	Q14C86
KQFSSFEKRAKIFCA	DDX58	851	O95786
KKLAFAFGDRNCSTI	DAG1	631	Q14118
QLAFGIDKSKSICVD	DYNC2LI1	236	Q8TCX1
LSRIKFTGKECEDSQ	DDX60L	1541	Q5H9U9
ISCREGKDSFKRIFS	DUSP10	216	Q9Y6W6
KKISTFIGTFLVCFA	GPR26	241	Q8NDV2
FVGQKSSFLVDCSKA	FLNB	2526	O75369
QKNFSVKDRCLFASF	PLXNC1	1076	O60486
QIRSAEGRKKAFSTC	OR3A3	236	P47888
TDFFSQRKVISFKGC	OR4F5	76	Q8NH21
SLDTADRFINSKCAK	NAA16	436	Q6N069
VVKSKCRENASPFFF	KLRK1	41	P26718
DLFNFCSRKFSLKTV	CSNK1D	91	P48730
IFKTGSEDCSKNFTS	NRP2	141	O60462
KARTSKACFQVGTSE	NUP214	721	P35658
FRFTPFKQAVKETCA	GFUS	296	Q13630
NKSFCEDLTEGKFSF	GGPS1	201	O95749
EARCFVTSFLESKTK	MSLNL	281	Q96KJ4
GCEREVSSFLSKKFQ	POLE	111	Q07864
QKEGEFSTCFTELQR	OAS1	181	P00973
TDFFSQRKVISFKGC	OR4F17	76	Q8NGA8
GKTEFNFLKCSEQLS	PCDHGB5	756	Q9Y5G0
AFVVVSCKESQSGFR	HECTD4	2591	Q9Y4D8
SIRAFCFDGTKAVKL	NSUN6	286	Q8TEA1
QLLNVGTKSTRFFCK	HIPK3	421	Q9H422
IRSAKDDFTSIIGKC	NBAS	111	A2RRP1
KTTQFSCTLGEKFEE	FABP5	61	Q01469
ALDTADRFINSKCAK	NAA15	436	Q9BXJ9
KGAQECTKTREFERF	PIK3CA	966	P42336
LSFKSRKCGDAFAEA	NLRC5	691	Q86WI3
CSAVEVKSKFGAEFR	PARD6G	16	Q9BYG4
FLSKFNCSRETVEFK	GPRC6A	116	Q5T6X5
GTFRVSDKSAFCKII	FANCD2OS	116	Q96PS1
KFKDGVESCAFDLTS	MCHR2	176	Q969V1
LSGKFREQFKAAFSC	HCRTR1	361	O43613
KGKRDARFFFSLCTD	PAPPA2	331	Q9BXP8
TFQLSKAEKFVFSGC	CCN6	271	O95389
CSKKLAGQRFTAVED	FHL1	191	Q13642
KLFAGINSVCFDEKS	DYNC2H1	1456	Q8NCM8
DFFSKAIQCARQEKS	ATM	211	Q13315
RIEAACFATIKDGKS	IDH3A	326	P50213
IFAASKNTTEKETFC	IL4	56	P05112
VIFGKSSCSEFSKEA	DOCK7	601	Q96N67
FFEIFKTRCNKADLG	BRCA2	11	P51587
KTKSQNVFRAGSCFV	CPLANE1	1606	Q9H799
SKTLSFFNKDTRGEV	COL12A1	2616	Q99715
RACFRQFFTKIKTAD	CDC37	231	Q16543
ATICRAEQEKASFKR	CROCC2	1091	H7BZ55
FTTRKTLANKFDCPV	CPHXL2	51	A0A1W2PPK0
KSFRFDCSTSIKDVI	FRMPD4	216	Q14CM0
RECAKAKGFFIDTRS	DIS3L	721	Q8TF46
FEGCEKAFSRLENLK	GLIS3	416	Q8NEA6
TDKRIFTFICKDSES	GULP1	106	Q9UBP9
FFSREADNVKDKLCS	CNPY2	151	Q9Y2B0
KCVQAARKESSDSFV	GALNT12	546	Q8IXK2
KTKDCGFLSQALSFR	DLG4	441	P78352
TETVKDLAKCALFAF	DNAH14	1171	Q0VDD8
RKSCSGFVQSDSKRE	MBD4	251	O95243
GFVQSDSKRESVCNK	MBD4	256	O95243
CSPTRKDFTGEKIFQ	MBD4	386	O95243
RSFDSEFKLACKVDG	DYNC1H1	4276	Q14204
TDIFVGSKGQKFLCT	CCDC168	3076	Q8NDH2
FKFRSQGSCLTKDIL	ERCC6L2	696	Q5T890
FEGCSKAFSRLENLK	GLIS1	266	Q8NBF1
SDRVFKAVSDICKTF	FERMT2	116	Q96AC1
DQLFCKKFAEALGST	GTF2I	471	P78347
EEFKTSIGRVNACLK	CHIC1	121	Q5VXU3
SKAFVCAFSKALQEE	HSD17B3	201	P37058
TSFCFRISKEKLDVA	RYR1	311	P21817
VFEQCGDITAIRKSK	ENOX1	161	Q8TC92
DGCAIFFKTEKFTLV	CNOT6	281	Q9ULM6
CRLRKGQTKTLFEFS	COL5A3	1696	P25940
ATDDSKAVCRLSVKF	ODC1	156	P11926
CNSETKSQFEKFVRF	KYAT3	416	Q6YP21
TVDSKRFFFDVGCNK	PURB	226	Q96QR8
CFAEEGQKLISKTRA	AFP	591	P02771
LNKEESKTCKFVSSF	MCMBP	326	Q9BTE3
LSEKKTISFAGCFLQ	OR5F1	86	O95221
FAEKKDITFLGCAAQ	OR5G3	86	P0C626
IGNCVSSFTAFVKRE	POFUT1	351	Q9H488
QIASAEGRKKTFATC	OR10J5	226	Q8NHC4
TDFFSQRKVISFKGC	OR4F4	76	Q96R69
FSFKTRAKSCGERDV	MAP3K5	996	Q99683
DLKQQEFFLGCSKVS	NAV1	1436	Q8NEY1
DSCIEAFGTTKQKRA	POLR1E	136	Q9GZS1
TFCLERFTKKSNSGF	UTP6	331	Q9NYH9
LRTFKDNFQTCKVEG	RGMB	171	Q6NW40
SLTKKLCEQDSTFDG	SPON1	176	Q9HCB6
TFKDSVFKSCTFEDV	SV2C	511	Q496J9
DCEVRATFAKKQGQS	WRAP53	311	Q9BUR4
SEKFFKAASNCGIVE	TOP2B	416	Q02880
FEAFGKIKSCTLARD	PUF60	246	Q9UHX1
FRCSSAKIKAVVFGL	SLC26A9	41	Q7LBE3
CNKTLKITDFGLARE	MAP3K21	281	Q5TCX8
RSLKEKCFLTQLAGF	NBPF10	36	Q6P3W6
FRSLKEKCFVTQLAG	NBPF12	306	Q5TAG4
SFCRKDFTDSQAAKT	PLCE1	281	Q9P212
IFCNGRSDLKSETYK	SAMD9L	496	Q8IVG5
SESLLKSKACFGAEN	GNL3L	221	Q9NVN8
IKSLSSFESGKFVEC	SMG1	1231	Q96Q15
KVAAGEFKSCTILFS	GUCY1B2	381	O75343
FTNKQVRITFGFSCK	MORC4	311	Q8TE76
RTNRVKECLAKGTFS	RHOBTB2	486	Q9BYZ6
KECLAKGTFSDVTFI	RHOBTB2	491	Q9BYZ6
KIRSTEGRQKAFSTC	OR5M8	226	Q8NGP6
LSQEKKASCGATEAF	PKHD1	4046	P08F94
DFALGFTCFESKTKN	SNTG2	446	Q9NY99
IKFCKALEIADFSGN	SCRIB	101	Q14160
LTFFKNRKCIGVAAT	SPSB3	231	Q6PJ21
SLSLKKEGERQCFLF	RASGRF1	481	Q13972
KLNTVGIAKFSCFTA	SLCO1B1	401	Q9Y6L6
IFIECTGTDFTKAKI	FARSB	251	Q9NSD9
FSRASECLKTGNRKA	SMCR8	176	Q8TEV9
SGTKQLLADFSCNKF	TGM3	666	Q08188
GLIFSCFIEDKNTKT	BRCC3	151	P46736
GEVENKSLVKSFLAC	AKAP17A	81	Q02040
FSIISKVDLFKGCDT	CNGB3	516	Q9NQW8
DGCAIFFKTEKFTLV	CNOT6L	281	Q96LI5
REKSFQCIESGKAFN	ZNF525	211	Q8N782
LKAAGCDFTNVVKTT	RIDA	66	P52758
FDSRKKNLCEEFART	RNF17	201	Q9BXT8
SQIKSKKFRCSGSED	SLIT3	476	O75094
NKCSKVFGRQSFLIE	ZNF667	446	Q5HYK9
EGKAAISNKITSCIF	PAICS	51	P22234
KECGKAFRLNSFLTE	ZNF30	571	P17039
NECGKSFRQKATLTV	ZNF567	536	Q8N184
LFECSNKTGRFLATE	VIL1	621	P09327
SECGKTFAQKFELTT	ZFP1	271	Q6P2D0
EECSKAFSNFSALRK	ZNF99	456	A8MXY4
EECGKAFNRFSTLTK	ZNF107	471	Q9UII5
CEEFGKAFKQSSHRT	ZNF107	526	Q9UII5
IECGKAFAEKSSLIN	ZNF586	181	Q9NXT0
EECGKAFSVFSTLTK	ZNF92	456	Q03936
EECGKAFTQFASLTR	ZNF678	296	Q5SXM1
TAKSQQSGEKAFRCE	ZNF143	226	P52747
ISLLKSGRFCDVFDK	VPS11	651	Q9H270
KQCGKAFIDFSSLTS	ZNF555	231	Q8NEP9
IGEKTLEFTDCRKAF	ZNF177	171	Q13360
AREIFSKFLCSKATT	RGS12	766	O14924
DCEKKGFTSLQRFTA	SLITRK1	41	Q96PX8
RLFGEKTCQFLSTFK	SERPINB9	91	P50453
TDDLLFTGSKDRTCK	KIF21A	1356	Q7Z4S6
DCRVSSFRVKENFDK	RBP4	21	P02753
LQEVESKIDGFKCFT	SNX18	421	Q96RF0
GKTFLDINKDSSCVS	TCN1	296	P20061
KRKVDEATFVTGCRF	ZNF551	161	Q7Z340
SECGKSFTRKSDLIQ	ZNF551	506	Q7Z340
KVIRNIACSGKFSSD	PYGB	801	P11216
GLQVESSCKVTDAKF	WDR72	646	Q3MJ13
DCEQKVSAKFFSEAV	THNSL1	241	Q8IYQ7
KNSKRLLFEVSSCFS	PKHD1L1	1551	Q86WI1
ASIFGTEKDKVNCSF	U2AF1	6	Q01081
SVKGLDVKSEACQRF	USP9Y	106	O00507
ASIFGTEKDKVNCSF	U2AF1L4	6	Q8WU68
GTQDSTDICKFFLKV	SNX6	256	Q9UNH7
FKKSFLRNCDLISGE	ZNF770	361	Q6IQ21
EECRKIFTSSSNFAK	ZNF141	286	Q15928
EECGKAFSRSSKLTE	ZNF675	511	Q8TD23
EECGKAFNKSSILTT	ZNF43	261	P17038
SFEDQRKKGFLCDIT	ZBTB24	26	O43167
IECGKAFKQFSTLTT	ZNF626	176	Q68DY1
GAKLCNIFSTKFTVE	TOP2A	166	P11388
KSFGSTCQLSEKFIK	TOP2A	386	P11388
NECGKTFSDKSALLV	ZNF888	301	P0CJ79
EECGKAFKRSSNLTT	ZNF90	456	Q03938
DECGKSFSQRTTLNK	ZNF416	441	Q9BWM5
KRCNSDFENTSKFSK	ZNF681	621	Q96N22
EECGKAFSRSSFLVQ	ZNF502	186	Q8TBZ5
REKSFQCIESGKSFN	ZNF28	211	P17035
EDCGKAFNRSSNLTK	ZNF66	456	Q6ZN08
SECGKTFVQKSTLRD	ZNF510	491	Q9Y2H8
LVKCFDKTFEISASD	SWAP70	276	Q9UH65
SLFESSCQQFDKLRK	TUBG2	386	Q9NRH3
ENESLFTFLGKKCVT	WASL	26	O00401
KCFDLRRKDSVSTFS	WDR24	146	Q96S15
TTIDDGSRCFFTKSK	TEX15	886	Q9BXT5
DICGKTFTFNSDLVR	ZNF623	126	O75123
GFLESKSTTCTRFFK	TCTN3	246	Q6NUS6
DSLKKEFESVFCGKT	TCFL5	456	Q9UL49
SSDNSKCFFKALESI	TOPBP1	16	Q92547
KLSDFGFSKRCLRDS	TSSK2	151	Q96PF2
REKSFECIQSFKSFN	ZNF468	211	Q5VIY5
NECGKAFRKSSTLIS	ZNF485	301	Q8NCK3
LCEKTSTGEKLSEFN	ZNF426	186	Q9BUY5
CKKLFSSSVSEGFQR	XK	376	P51811
KECGKVFNDSSTLRR	ZNF891	351	A8MT65
EECGKAFNRSSNLTK	ZNF506	316	Q5JVG8
ACSKEVFLDRKLGTQ	USP33	116	Q8TEY7
LAGSELFAKVKETCQ	ZC3H13	1536	Q5T200
EKANTCTEFGKIFTQ	ZNF81	271	P51508
KDCGKAFVVSSSLVD	ZNF560	631	Q96MR9
EECGKRFTENSKLRF	ZNF284	486	Q2VY69
EECGKAFSQSSTLRK	ZNF729	351	A6NN14
ECIKCGKFFRTDSQL	ZNF527	471	Q8NB42
DLFNFCSRKFSLKTV	CSNK1E	91	P49674
SKDFDCIITEFAKSQ	LGI1	216	O95970
EFGKTCLKTELQFSD	NAA25	451	Q14CX7