Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GABRG3 ANO9 STIM2 GRID1 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 SCN4A CACNA2D3 GABRA3 KCNH5

1.82e-0645911213GO:0005216
GeneOntologyMolecularFunctiongated channel activity

GABRG3 ANO9 GRID1 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 CACNA2D3 GABRA3 KCNH5

2.84e-0633411211GO:0022836
GeneOntologyMolecularFunctionchannel activity

GABRG3 ANO9 STIM2 GRID1 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 SCN4A CACNA2D3 GABRA3 KCNH5

7.83e-0652511213GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GABRG3 ANO9 STIM2 GRID1 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 SCN4A CACNA2D3 GABRA3 KCNH5

7.99e-0652611213GO:0022803
GeneOntologyMolecularFunctioncalcium channel activity

STIM2 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 CACNA2D3

8.23e-061291127GO:0005262
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GABRG3 ANO9 GRID1 GRIN2C GRIN2D RYR3 ITPR3 GABRA3

1.33e-051931128GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

GABRG3 ANO9 GRID1 GRIN2C GRIN2D RYR3 ITPR3 GABRA3

1.54e-051971128GO:0022834
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GABRG3 GRID1 GRIN2C GRIN2D GABRA3

1.68e-05571125GO:1904315
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GABRG3 GRID1 GRIN2C GRIN2D GABRA3

2.17e-05601125GO:0099529
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

STIM2 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 CACNA2D3

2.30e-051511127GO:0015085
GeneOntologyMolecularFunctionligand-gated calcium channel activity

GRIN2C GRIN2D RYR3 ITPR3

2.63e-05311124GO:0099604
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GABRG3 GRID1 GRIN2C GRIN2D GABRA3

3.21e-05651125GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GABRG3 GRID1 GRIN2C GRIN2D GABRA3

3.21e-05651125GO:0022824
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GABRG3 GRID1 GRIN2C GRIN2D GABRA3

6.41e-05751125GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GABRG3 GRID1 GRIN2C GRIN2D GABRA3

7.27e-05771125GO:0005230
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

GABRG3 ABCC1 ANO9 STIM2 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 COX5A SCN4A CACNA2D3 GABRA3 KCNH5

8.78e-0575811214GO:0015318
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

EPHB2 PDGFRB BMPR1A BMPR1B IGF1R

1.16e-04851125GO:0019199
GeneOntologyMolecularFunctionmonoatomic cation channel activity

STIM2 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 SCN4A CACNA2D3 KCNH5

1.36e-043431129GO:0005261
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

GABRG3 ANO9 STIM2 GRID1 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 COX5A SCN4A CACNA2D3 GABRA3 KCNH5

1.41e-0479311214GO:0015075
GeneOntologyMolecularFunctionRNA cap binding

LARP1 LARP1B EIF4E1B

2.12e-04211123GO:0000339
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GABRG3 GRID1 GRIN2C GRIN2D GABRA3

2.50e-041001125GO:0030594
GeneOntologyMolecularFunctioncalcium ion binding

UNC13B EFCAB5 PRRG2 DCHS2 STIM2 RCN2 DNAH7 RYR3 ITPR3 NKD1 MACF1 CDH3 CDH6

2.92e-0474911213GO:0005509
GeneOntologyMolecularFunctionpheromone binding

OBP2B OBP2A

3.08e-0451122GO:0005550
GeneOntologyMolecularFunctiontransforming growth factor beta receptor activity, type I

BMPR1A BMPR1B

3.08e-0451122GO:0005025
GeneOntologyMolecularFunctionglutamate receptor activity

GRID1 GRIN2C GRIN2D

4.55e-04271123GO:0008066
GeneOntologyMolecularFunctionBMP receptor activity

BMPR1A BMPR1B

8.54e-0481122GO:0098821
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIN2C GRIN2D

8.54e-0481122GO:0022849
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN2C GRIN2D

8.54e-0481122GO:0004972
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

STIM2 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 SCN4A CACNA2D3 KCNH5

1.23e-034651129GO:0046873
GeneOntologyMolecularFunctionbenzodiazepine receptor activity

GABRG3 GABRA3

1.66e-03111122GO:0008503
GeneOntologyMolecularFunctiontransporter activity

GABRG3 ABCC1 ANO9 STIM2 GRID1 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 IGF1R COX5A SCN4A CACNA2D3 GABRA3 KCNH5

2.22e-03128911216GO:0005215
GeneOntologyMolecularFunctiontransforming growth factor beta receptor activity

BMPR1A BMPR1B

2.34e-03131122GO:0005024
GeneOntologyMolecularFunctiontransmembrane transporter activity

GABRG3 ABCC1 ANO9 STIM2 GRID1 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 COX5A SCN4A CACNA2D3 GABRA3 KCNH5

2.45e-03118011215GO:0022857
GeneOntologyMolecularFunctionRNA 7-methylguanosine cap binding

LARP1 EIF4E1B

2.72e-03141122GO:0000340
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

GABRG3 ANO9 GABRA3

2.78e-03501123GO:0099095
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

STIM2 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 COX5A SCN4A CACNA2D3 KCNH5

2.78e-0362711210GO:0022890
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

GRIN2C GRIN2D CACNA2D4 CACNA2D3 KCNH5

3.64e-031821125GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

GRIN2C GRIN2D CACNA2D4 CACNA2D3 KCNH5

3.81e-031841125GO:0022832
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIN2C GRIN2D

4.01e-03171122GO:0004970
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

STIM2 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 COX5A SCN4A CACNA2D3 KCNH5

4.17e-0366411210GO:0008324
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR3 ITPR3

4.50e-03181122GO:0015278
GeneOntologyMolecularFunctionGABA-gated chloride ion channel activity

GABRG3 GABRA3

4.50e-03181122GO:0022851
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH7 KIFC3

4.50e-03181122GO:0008569
DomainKRAB

ZNF132 ZNF560 POGK ZNF862 ZNF772 ZNF551 ZNF557 ZNF773 ZNF547 ZNF713 ZNF530 ZNF792 ZNF75D

2.10e-0735811113PS50805
DomainKRAB

ZNF132 ZNF560 POGK ZNF862 ZNF772 ZNF551 ZNF557 ZNF773 ZNF547 ZNF713 ZNF530 ZNF792 ZNF75D

2.10e-0735811113PF01352
DomainKRAB

ZNF132 ZNF560 POGK ZNF862 ZNF772 ZNF551 ZNF557 ZNF773 ZNF547 ZNF713 ZNF530 ZNF792 ZNF75D

2.97e-0736911113SM00349
DomainKRAB

ZNF132 ZNF560 POGK ZNF862 ZNF772 ZNF551 ZNF557 ZNF773 ZNF547 ZNF713 ZNF530 ZNF792 ZNF75D

3.06e-0737011113IPR001909
DomainDM15

LARP1 LARP1B

3.50e-0521112SM00684
DomainDM15

LARP1 LARP1B

3.50e-0521112IPR006607
Domainvon_Ebner_gland

OBP2B OBP2A

1.05e-0431112IPR002450
DomainPkinase_Tyr

EPHB2 PDGFRB BMPR1A BMPR1B IGF1R HCK

1.21e-041291116PF07714
DomainLig_chan-Glu_bd

GRID1 GRIN2C GRIN2D

1.56e-04181113PF10613
DomainGlu/Gly-bd

GRID1 GRIN2C GRIN2D

1.56e-04181113IPR019594
DomainLig_chan-Glu_bd

GRID1 GRIN2C GRIN2D

1.56e-04181113SM00918
DomainIontro_rcpt

GRID1 GRIN2C GRIN2D

1.56e-04181113IPR001320
DomainIono_rcpt_met

GRID1 GRIN2C GRIN2D

1.56e-04181113IPR001508
DomainLig_chan

GRID1 GRIN2C GRIN2D

1.56e-04181113PF00060
DomainPBPe

GRID1 GRIN2C GRIN2D

1.56e-04181113SM00079
DomainSer-Thr/Tyr_kinase_cat_dom

EPHB2 PDGFRB BMPR1A BMPR1B IGF1R HCK

1.75e-041381116IPR001245
DomainVDCC_a2/dsu

CACNA2D4 CACNA2D3

2.08e-0441112IPR013680
DomainVGCC_alpha2

CACNA2D4 CACNA2D3

2.08e-0441112PF08473
DomainVWA_N

CACNA2D4 CACNA2D3

3.46e-0451112IPR013608
DomainVWA_N

CACNA2D4 CACNA2D3

3.46e-0451112PF08399
DomainRIH_assoc-dom

RYR3 ITPR3

5.17e-0461112IPR013662
DomainIns145_P3_rec

RYR3 ITPR3

5.17e-0461112PF08709
DomainRIH_assoc

RYR3 ITPR3

5.17e-0461112PF08454
DomainRIH_dom

RYR3 ITPR3

5.17e-0461112IPR000699
DomainIns145_P3_rcpt

RYR3 ITPR3

5.17e-0461112IPR014821
DomainRyanodine_recept-rel

RYR3 ITPR3

5.17e-0461112IPR015925
Domain-

RYR3 ITPR3

5.17e-04611121.25.10.30
DomainRYDR_ITPR

RYR3 ITPR3

5.17e-0461112PF01365
DomainZINC_FINGER_C2H2_2

ZNF132 ZNF560 ZNF772 ZNF551 ZNF557 ZNF773 ZNF547 ZNF713 ZNF530 ZNF792 JAZF1 ZNF75D ZC3H7B

6.91e-0477511113PS50157
DomainZINC_FINGER_C2H2_1

ZNF132 ZNF560 ZNF772 ZNF551 ZNF557 ZNF773 ZNF547 ZNF713 ZNF530 ZNF792 JAZF1 ZNF75D ZC3H7B

7.08e-0477711113PS00028
DomainGS_dom

BMPR1A BMPR1B

7.21e-0471112IPR003605
DomainLA

LARP1 LARP1B

7.21e-0471112SM00715
DomainGS

BMPR1A BMPR1B

7.21e-0471112PS51256
DomainTGF_beta_GS

BMPR1A BMPR1B

7.21e-0471112PF08515
DomainHTH_LA

LARP1 LARP1B

7.21e-0471112PS50961
DomainGS

BMPR1A BMPR1B

7.21e-0471112SM00467
DomainLa

LARP1 LARP1B

7.21e-0471112PF05383
DomainLupus_La_RNA-bd

LARP1 LARP1B

7.21e-0471112IPR006630
Domainzf-C2H2

ZNF132 ZNF560 ZNF772 ZNF551 ZNF557 ZNF773 ZNF547 ZNF713 ZNF530 ZNF792 JAZF1 ZNF75D

8.51e-0469311112PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF132 ZNF560 ZNF772 ZNF551 ZNF557 ZNF773 ZNF547 ZNF713 ZNF530 ZNF792 JAZF1 ZNF75D

8.62e-0469411112IPR013087
DomainZnf_C2H2-like

ZNF132 ZNF560 ZNF772 ZNF551 ZNF557 ZNF773 ZNF547 ZNF713 ZNF530 ZNF792 JAZF1 ZNF75D ZC3H7B

8.85e-0479611113IPR015880
DomainARM-type_fold

STK36 NBEAL1 MEI1 RYR3 INF2 UTP20 PRKDC GPRASP2

9.47e-043391118IPR016024
DomainCPDc

CTDSPL2 UBLCP1

9.57e-0481112SM00577
DomainVWA_3

CACNA2D4 CACNA2D3

9.57e-0481112PF13768
DomainHATC_C_dom

ZNF862 THAP12

9.57e-0481112IPR008906
DomainFCP1

CTDSPL2 UBLCP1

9.57e-0481112PS50969
DomainDimer_Tnp_hAT

ZNF862 THAP12

9.57e-0481112PF05699
DomainZnf_C2H2

ZNF132 ZNF560 ZNF772 ZNF551 ZNF557 ZNF773 ZNF547 ZNF713 ZNF530 ZNF792 JAZF1 ZNF75D ZC3H7B

9.80e-0480511113IPR007087
DomainZnF_C2H2

ZNF132 ZNF560 ZNF772 ZNF551 ZNF557 ZNF773 ZNF547 ZNF713 ZNF530 ZNF792 JAZF1 ZNF75D ZC3H7B

1.01e-0380811113SM00355
DomainNIF

CTDSPL2 UBLCP1

1.23e-0391112PF03031
DomainFCP1_dom

CTDSPL2 UBLCP1

1.23e-0391112IPR004274
DomainANF_lig-bd_rcpt

GRID1 GRIN2C GRIN2D

1.37e-03371113IPR001828
DomainANF_receptor

GRID1 GRIN2C GRIN2D

1.37e-03371113PF01094
DomainMIR

RYR3 ITPR3

1.53e-03101112PF02815
DomainMIR_motif

RYR3 ITPR3

1.53e-03101112IPR016093
DomainActivin_recp

BMPR1A BMPR1B

1.53e-03101112PF01064
DomainMIR

RYR3 ITPR3

1.53e-03101112PS50919
DomainMIR

RYR3 ITPR3

1.53e-03101112SM00472
DomainActivin_recp

BMPR1A BMPR1B

1.53e-03101112IPR000472
DomainPeripla_BP_I

GRID1 GRIN2C GRIN2D

1.60e-03391113IPR028082
DomainTyr_kinase_cat_dom

EPHB2 PDGFRB IGF1R HCK

1.88e-03881114IPR020635
DomainTyrKc

EPHB2 PDGFRB IGF1R HCK

1.88e-03881114SM00219
DomainTGFB_receptor

BMPR1A BMPR1B

2.22e-03121112IPR000333
Domain-

ZNF132 ZNF560 ZNF772 ZNF551 ZNF557 ZNF773 ZNF547 ZNF530 ZNF792 JAZF1 ZNF75D

2.37e-03679111113.30.160.60
DomainEF_HAND_2

EFCAB5 STIM2 RCN2 RYR3 NKD1 MACF1

2.58e-032311116PS50222
DomainHTH_Tnp_Tc5

DCHS2 POGK

2.62e-03131112PF03221
DomainEF_hand_dom

EFCAB5 RCN2 DNAH7 RYR3 NKD1 MACF1

2.64e-032321116IPR002048
DomainPROTEIN_KINASE_TYR

EPHB2 PDGFRB IGF1R HCK

2.68e-03971114PS00109
DomainTyr_kinase_AS

EPHB2 PDGFRB IGF1R HCK

2.68e-03971114IPR008266
DomainTPR-like_helical_dom

POLR1A USP28 TRAPPC8 PRKDC ZC3H7B FKBP4

2.69e-032331116IPR011990
DomainHEAT

STK36 UTP20 PRKDC

2.91e-03481113PF02985
DomainEF_Hand_1_Ca_BS

EFCAB5 RCN2 DNAH7 NKD1 MACF1

3.93e-031751115IPR018247
DomainLIPOCALIN

OBP2B OBP2A

4.49e-03171112PS00213
DomainIon_trans_dom

RYR3 ITPR3 SCN4A KCNH5

4.78e-031141114IPR005821
DomainIon_trans

RYR3 ITPR3 SCN4A KCNH5

4.78e-031141114PF00520
DomainHEAT

STK36 UTP20 PRKDC

4.97e-03581113IPR000357
DomainKinase-like_dom

EPHB2 STK36 PDGFRB BMPR1A BMPR1B IGF1R MACF1 PRKDC HCK

5.03e-035421119IPR011009
DomainLipocalin

OBP2B OBP2A

5.03e-03181112IPR002345
Pubmed

Bone morphogenetic proteins, eye patterning, and retinocollicular map formation in the mouse.

EPHB2 BMPR1A BMPR1B

1.33e-074113318614674
Pubmed

Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses.

BMPR1A BMPR1B BMP10

1.85e-068113316049014
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

POLR1A PRPF8 F5 ITPR3 BLMH EEF1G GTF3C1 COX5A YLPM1 MACF1 UTP20 PRKDC NOP2 FKBP4

6.18e-0610241131424711643
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

POLR1A LARP1 PRPF8 ITPR3 GTF3C1 YLPM1 MACF1 UTP20 PRKDC NOP2 FKBP4

9.68e-066531131122586326
Pubmed

Cloning and characterization of cDNAs encoding mouse Ugt1.6 and rabbit UGT1.6: differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

UGT1A5 UGT1A3

1.05e-05211328068691
Pubmed

Assignment of the BMPR1A and BMPR1B genes to human chromosome 10q22.3 and 4q23-->q24 byin situ hybridization and radiation hybrid map ping.

BMPR1A BMPR1B

1.05e-05211329730621
Pubmed

Expression of bone morphogenetic protein receptors type-IA, -IB and -II correlates with tumor grade in human prostate cancer tissues.

BMPR1A BMPR1B

1.05e-052113210850425
Pubmed

Differential molecular regulation of processing and membrane expression of Type-I BMP receptors: implications for signaling.

BMPR1A BMPR1B

1.05e-052113228357470
Pubmed

Phosphorylation of Doc2 by EphB2 modulates Munc13-mediated SNARE complex assembly and neurotransmitter release.

EPHB2 UNC13B

1.05e-052113238758791
Pubmed

Serum starvation and growth factor receptor expression in vascular smooth muscle cells.

PDGFRB IGF1R

1.05e-052113216407661
Pubmed

Distinct roles of BMP receptors Type IA and IB in osteo-/chondrogenic differentiation in mesenchymal progenitors (C3H10T1/2).

BMPR1A BMPR1B

1.05e-052113215322331
Pubmed

A novel human odorant-binding protein gene family resulting from genomic duplicons at 9q34: differential expression in the oral and genital spheres.

OBP2B OBP2A

1.05e-052113210607840
Pubmed

BMPR1A is necessary for chondrogenesis and osteogenesis, whereas BMPR1B prevents hypertrophic differentiation.

BMPR1A BMPR1B

1.05e-052113232764110
Pubmed

[BMP7 signaling via BMPR1A, BMPR1B inhibits the proliferation of lung large carcinoma NCI-H460 cell].

BMPR1A BMPR1B

1.05e-052113220673479
Pubmed

Rare loss of function mutations in N-methyl-D-aspartate glutamate receptors and their contributions to schizophrenia susceptibility.

GRIN2C GRIN2D

1.05e-052113229317596
Pubmed

NMDA GluN2C/2D receptors contribute to synaptic regulation and plasticity in the anterior cingulate cortex of adult mice.

GRIN2C GRIN2D

1.05e-052113233766086
Pubmed

In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons.

GRIN2C GRIN2D

1.05e-052113229651654
Pubmed

Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes.

GRIN2C GRIN2D

1.05e-052113231110197
Pubmed

Chromosomal mapping of genes involved in growth control.

PDGFRB IGF1R

1.05e-05211323107886
Pubmed

Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development.

BMPR1A BMPR1B

1.05e-052113215102710
Pubmed

Evidence of an odorant-binding protein in the human olfactory mucus: location, structural characterization, and odorant-binding properties.

OBP2B OBP2A

1.05e-052113212044155
Pubmed

Enhanced function of NR2C/2D-containing NMDA receptor in the nucleus accumbens contributes to peripheral nerve injury-induced neuropathic pain and depression in mice.

GRIN2C GRIN2D

1.05e-052113235057644
Pubmed

GSK1904529A, a Potent IGF-IR Inhibitor, Reverses MRP1-Mediated Multidrug Resistance.

ABCC1 IGF1R

1.05e-052113228266043
Pubmed

NMDA receptors containing GluN2C and GluN2D subunits have opposing roles in modulating neuronal oscillations; potential mechanism for bidirectional feedback.

GRIN2C GRIN2D

1.05e-052113231786200
Pubmed

BMPR1A and BMPR1B Missense Mutations Cause Primary Ovarian Insufficiency.

BMPR1A BMPR1B

1.05e-052113231769494
Pubmed

Bmp in podocytes is essential for normal glomerular capillary formation.

DES BMPR1A BMPR1B

1.18e-0514113318272846
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

EFCAB5 STIM2 CTDSPL2 LARP1 PRPF8 UBLCP1 PCF11 DES BMPR1A BMPR1B GTF3C1 SCN4A YLPM1 MACF1 PRKDC METTL25

1.76e-0514421131635575683
Pubmed

Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development.

PDGFRB DES CDH6

1.81e-0516113324353058
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

UNC13B GLIPR1 DCHS2 PDGFRB SYNM USP28 PRPF8 RYR3 YLPM1 MACF1 PRKDC KIFC3 GPRASP2 USP33 SNX5

1.83e-0512851131535914814
Pubmed

Genome-wide association of serum bilirubin levels in Korean population.

DCHS2 UGT1A5 UGT1A3

2.20e-0517113320639394
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

POGK RCN2 LARP1 PRPF8 PCF11 BLMH BMPR1A GTF3C1 INF2 YLPM1 PRKDC KIFC3 NOP2 KNL1

2.36e-0511551131420360068
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

STIM2 SYNM RCN2 NBN TRAPPC8 PRPF8 ITPR3 PCF11 COX5A INF2 ANKRD11 MACF1 NOP2 FKBP4 USP33 SNX5

2.55e-0514871131633957083
Pubmed

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.

NBN PHF8 EEF1G PRKDC NOP2

2.58e-05106113519394292
Pubmed

Auditory pathway and auditory brainstem response in mice lacking NMDA receptor epsilon 1 and epsilon 4 subunits.

GRIN2C GRIN2D

3.13e-05311329718984
Pubmed

Possible pheromone-carrier function of two lipocalin proteins in the vomeronasal organ.

OBP2B OBP2A

3.13e-05311327813422
Pubmed

The mouse synemin gene encodes three intermediate filament proteins generated by alternative exon usage and different open reading frames.

SYNM DES

3.13e-053113215265691
Pubmed

Desmuslin, an intermediate filament protein that interacts with alpha -dystrobrevin and desmin.

SYNM DES

3.13e-053113211353857
Pubmed

Age-Associated Increase in BMP Signaling Inhibits Hippocampal Neurogenesis.

BMPR1A BMPR1B

3.13e-053113225538007
Pubmed

Dendrite complexity of sympathetic neurons is controlled during postnatal development by BMP signaling.

BMPR1A BMPR1B

3.13e-053113224048844
Pubmed

Distinct developmental programs require different levels of Bmp signaling during mouse retinal development.

BMPR1A BMPR1B

3.13e-053113215673568
Pubmed

Vimentin knockout results in increased expression of sub-endothelial basement membrane components and carotid stiffness in mice.

SYNM DES

3.13e-053113228912461
Pubmed

Isolation and characterization of a UDP-glucuronosyltransferase (UGT1A01) cloned from female rhesus monkey.

UGT1A5 UGT1A3

3.13e-053113212051676
Pubmed

Expression patterns of BMPRs in the developing mouse molar.

BMPR1A BMPR1B

3.13e-053113216432712
Pubmed

Analysis of the native murine bone morphogenetic protein serine threonine kinase type I receptor (ALK-3).

BMPR1A BMPR1B

3.13e-05311328707881
Pubmed

The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways.

BMPR1A BMPR1B

3.13e-053113211714695
Pubmed

Transdifferentiation of alveolar epithelial type II to type I cells is controlled by opposing TGF-β and BMP signaling.

BMPR1A BMPR1B

3.13e-053113223831617
Pubmed

The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.

BMPR1A BMPR1B

3.13e-053113225413979
Pubmed

Granulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development.

BMPR1A BMPR1B

3.13e-053113220363875
Pubmed

Adipose-derived lipocalin 14 alleviates hyperglycaemia by suppressing both adipocyte glycerol efflux and hepatic gluconeogenesis in mice.

OBP2B OBP2A

3.13e-053113226592241
Pubmed

BMP signaling specifies the development of a large and fast CNS synapse.

BMPR1A BMPR1B

3.13e-053113223708139
Pubmed

Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis.

BMPR1A BMPR1B

3.13e-05311327750489
Pubmed

BMPR1a and BMPR1b signaling exert opposing effects on gliosis after spinal cord injury.

BMPR1A BMPR1B

3.13e-053113220130193
Pubmed

Bone morphogenetic protein type IB receptor is progressively expressed in malignant glioma tumours.

BMPR1A BMPR1B

3.13e-05311328605097
Pubmed

Biomechanical Properties of the Sarcolemma and Costameres of Skeletal Muscle Lacking Desmin.

SYNM DES

3.13e-053113234489727
Pubmed

A role for UDP-glucose glycoprotein glucosyltransferase in expression and quality control of MHC class I molecules.

UGT1A5 UGT1A3

3.13e-053113221383159
Pubmed

Dual targeting of IGF-1R and PDGFR inhibits proliferation in high-grade gliomas cells and induces radiosensitivity in JNK-1 expressing cells.

PDGFRB IGF1R

3.13e-053113217568996
Pubmed

Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens.

GRIN2C GRIN2D

3.13e-053113235867797
Pubmed

Role of type I receptors for anti-Müllerian hormone in the SMAT-1 Sertoli cell line.

BMPR1A BMPR1B

3.13e-053113215897891
Pubmed

Soluble LR11/SorLA represses thermogenesis in adipose tissue and correlates with BMI in humans.

BMPR1A BMPR1B

3.13e-053113226584636
Pubmed

Expression of bone morphogenetic protein receptors in the developing mouse metanephros.

BMPR1A BMPR1B

3.13e-053113211701996
Pubmed

Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a hemiparkinsonian mouse model.

GRIN2C GRIN2D

3.13e-053113233421565
Pubmed

P-cadherin potentiates ligand-dependent EGFR and IGF-1R signaling in dysplastic and malignant oral keratinocytes.

IGF1R CDH3

3.13e-053113225322858
Pubmed

The transforming growth factor-beta type III receptor mediates distinct subcellular trafficking and downstream signaling of activin-like kinase (ALK)3 and ALK6 receptors.

BMPR1A BMPR1B

3.13e-053113219726563
Pubmed

Concomitant high expression of BRAFV600E, P-cadherin and cadherin 6 is associated with High TNM stage and lymph node metastasis in conventional papillary thyroid carcinoma.

CDH3 CDH6

3.13e-053113226285159
Pubmed

Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit.

CACNA2D4 CACNA2D3

3.13e-053113212181424
Pubmed

Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels.

GRIN2C GRIN2D

3.13e-05311329480759
Pubmed

Enhanced expression of type I receptors for bone morphogenetic proteins during bone formation.

BMPR1A BMPR1B

3.13e-05311328592941
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ABCC1 CTDSPL2 RCN2 NBN PHF8 UBLCP1 ITPR3 PCF11 BLMH YLPM1 KIAA1328 FKBP4 KNL1

3.76e-0510491131327880917
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

POLR1A CTDSPL2 PRPF8 F5 ITPR3 INF2 YLPM1 MACF1 PRKDC NOP2

6.09e-056601131032780723
Pubmed

Characterization of the binding sites for the interactions between FKBP12 and intracellular calcium release channels.

RYR3 ITPR3

6.25e-054113222100703
Pubmed

Bone morphogenetic protein 4 (BMP4) signaling in retinoblastoma cells.

BMPR1A BMPR1B

6.25e-054113221152263
Pubmed

Oligomeric interactions of TGF-β and BMP receptors.

BMPR1A BMPR1B

6.25e-054113222293501
Pubmed

Role of alpha2/delta subunit in the development of morphine-induced rewarding effect and behavioral sensitization.

CACNA2D4 CACNA2D3

6.25e-054113219596051
Pubmed

Common genetic variants of the BMP4, BMPR1A, BMPR1B, and ACVR1 genes, left ventricular mass, and other parameters of the heart in newborns.

BMPR1A BMPR1B

6.25e-054113222971142
Pubmed

RIM proteins activate vesicle priming by reversing autoinhibitory homodimerization of Munc13.

UNC13B BMPR1B

6.25e-054113221262469
Pubmed

Effect of bone morphogenetic protein-6 on haemopoietic stem cells and cytokine production in normal human bone marrow stroma.

BMPR1A BMPR1B

6.25e-054113211401330
Pubmed

HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression.

BMPR1A BMPR1B

6.25e-054113224904118
Pubmed

LTP of inhibition at PV interneuron output synapses requires developmental BMP signaling.

BMPR1A BMPR1B

6.25e-054113232572071
Pubmed

Mutations in the BMP pathway in mice support the existence of two molecular classes of holoprosencephaly.

BMPR1A BMPR1B

6.25e-054113217913790
Pubmed

Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor.

UGT1A5 UGT1A3

6.25e-054113212644700
Pubmed

Synergistic effects of different bone morphogenetic protein type I receptors on alkaline phosphatase induction.

BMPR1A BMPR1B

6.25e-054113211282024
Pubmed

Expression of bone morphogenetic protein-2 and its receptors in epithelial ovarian cancer and their influence on the prognosis of ovarian cancer patients.

BMPR1A BMPR1B

6.25e-054113220587070
Pubmed

The prevalence of MADH4 and BMPR1A mutations in juvenile polyposis and absence of BMPR2, BMPR1B, and ACVR1 mutations.

BMPR1A BMPR1B

6.25e-054113215235019
Pubmed

A GDF5 point mutation strikes twice--causing BDA1 and SYNS2.

BMPR1A BMPR1B

6.25e-054113224098149
Pubmed

An increase in expression of the lipocalin 24p3 is found in mouse uterus coincident with birth.

OBP2B OBP2A

6.25e-05411327544071
Pubmed

The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling.

BMPR1A BMPR1B

6.25e-054113226701726
Pubmed

Chromosomal localization of three human genes encoding bone morphogenetic protein receptors.

BMPR1A BMPR1B

6.25e-054113210051328
Pubmed

Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.

GRIN2C GRIN2D

6.25e-054113236309015
Pubmed

Vascular smooth muscle cells express multiple type I receptors for TGF-beta, activin, and bone morphogenetic proteins.

BMPR1A BMPR1B

6.25e-05411328605036
Pubmed

Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse.

PDGFRB DES

6.25e-054113210375497
Pubmed

Roles for NBS1 in alternative nonhomologous end-joining of V(D)J recombination intermediates.

NBN PRKDC

6.25e-054113219362533
Pubmed

Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors.

BMPR1A BMPR1B

6.25e-054113210712517
Pubmed

Functional correlation of NMDA receptor epsilon subunits expression with the properties of single-channel and synaptic currents in the developing cerebellum.

GRIN2C GRIN2D

6.25e-05411328699248
Pubmed

MDC1 regulates DNA-PK autophosphorylation in response to DNA damage.

NBN PRKDC

6.25e-054113215377652
Pubmed

Duplications involving a conserved regulatory element downstream of BMP2 are associated with brachydactyly type A2.

BMPR1A BMPR1B

6.25e-054113219327734
Pubmed

P-cadherin cooperates with insulin-like growth factor-1 receptor to promote metastatic signaling of gonadotropin-releasing hormone in ovarian cancer via p120 catenin.

IGF1R CDH3

6.25e-054113221317933
Pubmed

Role of the carboxy-terminal region of the GluR epsilon2 subunit in synaptic localization of the NMDA receptor channel.

GRIN2C GRIN2D

6.25e-05411329768843
Pubmed

Regulation of RNA polymerase III transcription by Maf1 in mammalian cells.

POLR3F GTF3C1

6.25e-054113218377933
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

ABCC1 CTDSPL2 NBN PHF8 PRPF8 ITPR3 GTF3C1 COX5A YLPM1 ANKRD11 JAZF1 UTP20 PRKDC NOP2

8.04e-0512941131430804502
Pubmed

The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage.

BMPR1A BMPR1B BMP10

8.22e-0526113331311865
Cytoband19q13.43

ZNF772 ZNF551 ZNF773 ZNF547 ZNF530

2.60e-0687113519q13.43
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF132 ZNF560 ZNF862 ZNF772 ZNF551 ZNF557 ZNF773 ZNF547 ZNF713 ZNF530 ZNF792 JAZF1 ZNF75D

4.22e-05718881328
GeneFamilyLa ribonucleoprotein domain containing|RNA binding motif containing

LARP1 LARP1B

4.84e-047882625
GeneFamilyType 1 receptor serine/threonine kinases

BMPR1A BMPR1B

4.84e-047882345
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2C GRIN2D

4.84e-0478821201
GeneFamilyCTD family phosphatases

CTDSPL2 UBLCP1

6.43e-0488821041
GeneFamilyEF-hand domain containing

EFCAB5 RCN2 DNAH7 RYR3 NKD1 MACF1

7.00e-04219886863
GeneFamilyLipocalins

OBP2B OBP2A

3.80e-0319882631
GeneFamilyGamma-aminobutyric acid type A receptor subunits

GABRG3 GABRA3

3.80e-0319882563
ToppCellPericytes|World / shred by cell class for parenchyma

GLIPR1 PDGFRB SYNM DES NKD1 AEBP1 CDH6

6.99e-0719611378e7ecbe77d312a7fc6aadd8fd52c13dd1834cc7e
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

UNC13B DCHS2 OBP2B RYR3 CDH6 KCNH5

4.50e-0616811367abaddbcc55e44653d54aa15464266aa6bd5c9d2
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

BMPR1B CDH6 FKBP4 WWC1 CACNA2D3 FAM149A

5.88e-06176113636f77d878a53b30465b0dea8333a3865dba75613
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

UNC13B DCHS2 OBP2B RYR3 CDH6 KCNH5

6.07e-0617711364c069f0d044a96118090b85ca592a21d6b5d9399
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EFCAB5 PDGFRB SYNM DES SCN4A CDH6

6.07e-061771136d731400997afea379f47ae8aa0f82802962b0861
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

PDGFRB SYNM DES NKD1 AEBP1 CDH6

6.68e-061801136d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

UNC13B DCHS2 OBP2B RYR3 CDH6 KCNH5

6.90e-06181113608f44323bf71b6004a921bbc969c954c75feeb66
ToppCellPericytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

PDGFRB SYNM DES NKD1 AEBP1 CDH6

7.12e-06182113646c213597445b1f4f09dc367f27702d24b201daf
ToppCellPericytes-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

PDGFRB SYNM DES NKD1 AEBP1 CDH6

7.58e-061841136cd10d351d91a81dd6dc806cb4e0c8d7861c98e0b
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHB2 PDGFRB AEBP1 GPRASP2 GABRA3 FAM149A

8.31e-061871136ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

NBEAL1 RYR3 PTCHD1 NKD1 MACF1 CDH6

8.83e-0618911366b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 DNAH7 ITPR3 CDH3 WWC1 CACNA2D3

9.10e-0619011363fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellPericytes|World / lung cells shred on cell class, cell subclass, sample id

PDGFRB SYNM DES NKD1 AEBP1 CDH6

9.66e-061921136057ad22b878c0c5fb59ed1412ca13db945c57a5a
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B ANO9 DNAH7 CFAP299 WWC1 FAM149A

9.66e-061921136b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLIPR1 SYNM RYR3 DES PTCHD1 MACF1

9.95e-0619311360256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B DNAH7 CFAP299 CDH3 WWC1 FAM149A

1.02e-051941136f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell(1)_T_cells-(1)_T_CD8_CTL|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PDGFRB SYNM HLA-DQA2 USP28 GTF3C1 BIN2

1.09e-051961136ad9b0651cb2a15b750e453b2dcf782bca08b4fe7
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)|367C / Donor, Lineage, Cell class and subclass (all cells)

PDGFRB SYNM DES NKD1 AEBP1 CDH6

1.09e-051961136c390ef0adff35111989a30dff86b7c5db1a89873
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)-|367C / Donor, Lineage, Cell class and subclass (all cells)

PDGFRB SYNM DES NKD1 AEBP1 CDH6

1.09e-0519611362f76f050083483f0880639e6c34ff349caac3503
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDGFRB SYNM DES NKD1 AEBP1 CDH6

1.12e-05197113601249bd485a3734de87ae6ed9c749597f39c6335
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_2|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GLIPR1 HLA-DQA2 GRIN2D TLR8 HCK CACNA2D3

1.12e-051971136febafd8f0f5bb9a09f496f240e6b6b5e9275669b
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDGFRB SYNM DES PRSS53 CDH6 CACNA2D3

1.12e-051971136ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EFCAB5 SYNM TLR8 CDH6 KCNH5

1.13e-051151135ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EFCAB5 SYNM TLR8 CDH6 KCNH5

1.13e-0511511357a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EFCAB5 SYNM TLR8 CDH6 KCNH5

1.13e-051151135c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PDGFRB SYNM DES NKD1 AEBP1 CDH6

1.15e-051981136705118a5db366b43ffd3389c60e4cb392ad3f2e6
ToppCellcellseq-Mesenchymal-Myocytic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PDGFRB SYNM DES NKD1 AEBP1 CDH6

1.18e-05199113620e62a7029fa0d214244cdf2a481fc5d78290438
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PDGFRB SYNM DES NKD1 AEBP1 CDH6

1.18e-0519911360a145172787f40d0fdaf21188d539ffaf7ece3e4
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PDGFRB SYNM DES NKD1 AEBP1 CDH6

1.18e-0519911368ff0fdcbe9661b013913731ec8b53d84836ca865
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PDGFRB SYNM DES NKD1 AEBP1 CDH6

1.18e-051991136ad75e5e26c37a97331164d7f77235ebd9a933a44
ToppCellParenchyma_COVID-19-Stromal-TX-Smooth_muscle-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PDGFRB SYNM DES NKD1 AEBP1 CDH6

1.18e-051991136c8bc05dece8b8a87d4a7a3e8112b924e15217de1
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDGFRB SYNM DES NKD1 AEBP1 CDH6

1.18e-05199113678b245d40c1e169ff2d26907b63d732e34529c5f
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDGFRB SYNM DES NKD1 AEBP1 CDH6

1.18e-0519911368e1e95c3a4b856415af208be6ad977e575bac189
ToppCellMacroglial-Astrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

PDGFRB GRIN2C DNAH7 RYR3 BMPR1B WWC1

1.22e-052001136941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCellMacroglial-Astrocytes-SLC14A1---|Macroglial / cells hierarchy compared to all cells using T-Statistic

PDGFRB GRIN2C DNAH7 RYR3 BMPR1B WWC1

1.22e-052001136d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCellMacroglial-Astrocytes-SLC14A1----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

PDGFRB GRIN2C DNAH7 RYR3 BMPR1B WWC1

1.22e-052001136f861509b54185d89931db64da1b9d81986cc7938
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DCHS2 GRIN2C DNAH7 RYR3 BMPR1B MACF1

1.22e-05200113607d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DCHS2 GRIN2C DNAH7 RYR3 BMPR1B MACF1

1.22e-052001136d0812817ef99608994193787a62d39adeb2070ca
ToppCellMacroglial-Astrocytes-SLC14A1|Macroglial / cells hierarchy compared to all cells using T-Statistic

PDGFRB GRIN2C DNAH7 RYR3 BMPR1B WWC1

1.22e-05200113616f468217427921fa18c6d078ffa990eb019b257
ToppCellMacroglial-Astrocytes-SLC14A1--|Macroglial / cells hierarchy compared to all cells using T-Statistic

PDGFRB GRIN2C DNAH7 RYR3 BMPR1B WWC1

1.22e-0520011360442894c39eec69850c090957a5dc7bcecd21e04
ToppCellMacroglial-Astrocytes-SLC14A1-|Macroglial / cells hierarchy compared to all cells using T-Statistic

PDGFRB GRIN2C DNAH7 RYR3 BMPR1B WWC1

1.22e-05200113601819446deeab9054f5cfe889d53bb49d137dbc0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DCHS2 GRIN2C DNAH7 RYR3 BMPR1B MACF1

1.22e-052001136cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Smooth_Muscle-like_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

EPHB2 DES PTCHD1 KIFC3 CDH6

2.91e-0514011355623a0a68403fc00166b7d13d13e184a718d9bdd
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPHB2 GABRG3 ABCC1 TLR8 ZNF773

3.56e-051461135b76110b159acd27a2c8d6a9f98336608ace1ec12
ToppCellCOVID-19_Severe-MAIT|COVID-19_Severe / disease group, cell group and cell class

CACNA2D4 NKD1 ZNF75D DSEL CDH3

4.05e-051501135923ea7ecc0aa05fb0396082cd9c3d1594135f1e0
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GLIPR1 MEI1 GRHL1 BMPR1B INF2

5.18e-0515811359e0589f770920f8ac41cfe5cd0a29e9e7a04a308
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

PDGFRB OBP2A NBEAL1 PTCHD1 CDH6

6.37e-051651135f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

UNC13B PTCHD1 GRHL1 BMPR1B WWC1

7.33e-051701135a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCHS2 OBP2B RYR3 CDH6 KCNH5

7.33e-051701135417b77c12a7982b1ce4b4bc57f30335d261220f5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 CDH3 CDH6 WWC1 CACNA2D3

7.75e-0517211350c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 CDH3 CDH6 WWC1 CACNA2D3

7.75e-051721135eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Basophil|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GLIPR1 GRIN2D F5 BIN2 PRKDC

7.96e-0517311352cba41c3d9d3076f703115d19729073a3ac3feb6
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GLIPR1 GRIN2D F5 BIN2 PRKDC

7.96e-05173113511d69a4ab4a87b8820cd3bd204de8c4124450a90
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

PDGFRB SYNM DES AEBP1 CDH6

8.40e-051751135fed9e4120c758fdcc23bb248d1801002b0e0d485
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB SYNM NBEAL1 GRID1 DES

8.40e-051751135316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB SYNM NBEAL1 GRID1 DES

8.40e-051751135a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GABRG3 PDGFRB GRID1 NKD1 CDH6

8.87e-0517711354943d040eee0f9dceaddc7498171281d170e271f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GABRG3 PDGFRB GRID1 NKD1 CDH6

8.87e-0517711353f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCHS2 OBP2B RYR3 CDH6 KCNH5

8.87e-051771135bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCHS2 OBP2B RYR3 CDH6 KCNH5

9.10e-051781135431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCellCOPD-Stromal-SMC|COPD / Disease state, Lineage and Cell class

PDGFRB SYNM DES AEBP1 CDH6

9.35e-0517911355c705627bd13a5b2c7b0062fb3d94e4eb1589327
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCHS2 OBP2B RYR3 CDH6 KCNH5

9.35e-051791135f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCellCOPD-Stromal-SMC|World / Disease state, Lineage and Cell class

PDGFRB SYNM DES AEBP1 CDH6

9.35e-051791135b2709537ec1b46457ab85261f4cdd354e60a8b29
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCHS2 OBP2B RYR3 CDH6 KCNH5

9.60e-051801135b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PDGFRB SYNM GRID1 NKD1 CDH6

9.85e-051811135451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellPericytes-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DCHS2 PDGFRB NKD1 AEBP1 CDH6

9.85e-05181113535c470988a93381eefa300831aabb813fa1b90bd
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

UNC13B PTCHD1 GRHL1 BMPR1B FAM149A

9.85e-051811135c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PDGFRB USP28 GTF3C1 BIN2 DSEL

1.04e-041831135983ca1342ddd365e1f1df32a456394b002b10e41
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

PDGFRB F5 RYR3 NKD1 INF2

1.04e-041831135fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB F5 RYR3 NKD1 INF2

1.04e-041831135848fc6dd129150897ee339343e83c645b6e779eb
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCHS2 OBP2B RYR3 CDH6 KCNH5

1.04e-04183113565f2a5895d166189a095cf7ea9dda171f0419b08
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM DES PTCHD1 NKD1 AEBP1

1.04e-04183113561a73de857f4ae02dcba3af348f436f602b28ff2
ToppCellwk_08-11-Hematologic-Myeloid-DC3|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GLIPR1 TLR8 BIN2 HCK CACNA2D3

1.06e-0418411357d9294e5a55964903feda135e5bea0338824ed83
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-ACTC+_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SYNM DES PTCHD1 BMPR1B CDH3

1.06e-04184113539168ca2bbf1369c9fe87c67f0aaff5e3cd03151
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DES ZNF713 NKD1 AEBP1 CDH6

1.06e-04184113554e5b63f55b8d6eccad53d389ea9c78f991e1414
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DES ZNF713 NKD1 AEBP1 CDH6

1.06e-0418411357b5678718719020b52e7c2a7bd9797987defd7ff
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

UNC13B PTCHD1 GRHL1 WWC1 FAM149A

1.09e-04185113598b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

UNC13B GRHL1 BMPR1B WWC1 FAM149A

1.09e-041851135cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DES BMPR1A AEBP1 CDH3 CDH6

1.09e-041851135e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB F5 RYR3 NKD1 INF2

1.09e-041851135b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH7 JAZF1 CDH6 WWC1 CACNA2D3

1.12e-041861135f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EPHB2 RYR3 NKD1 CDH6 CACNA2D3

1.15e-0418711355258674d0346e5c51a4b965efcdc1790c970845d
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

UNC13B PTCHD1 GRHL1 WWC1 FAM149A

1.15e-04187113581cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH7 JAZF1 CDH6 WWC1 CACNA2D3

1.15e-041871135c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellPericytes-HP_01|World / lung cells shred on cell class, cell subclass, sample id

PDGFRB DES NKD1 AEBP1 CDH6

1.15e-04187113535f25780d113f60bf4c13749013c09612ee4ff41
ToppCellIPF-Stromal-SMC|World / Disease state, Lineage and Cell class

PDGFRB SYNM DES AEBP1 CDH6

1.18e-041881135b66264e8f8d536ed2beec31e6746c687718f239b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GRID1 DES PTCHD1 NKD1

1.18e-041881135b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

NBEAL1 RYR3 PTCHD1 NKD1 MACF1

1.18e-04188113534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GLIPR1 RYR3 DES NKD1 CDH6

1.18e-04188113574f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH7 JAZF1 CDH6 WWC1 CACNA2D3

1.18e-041881135af740fa78542438fdff627ea1f74f4eee43316be
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

PDGFRB SYNM GRID1 NKD1 CDH6

1.18e-041881135ee151792c7ac9afe820f1a281c6dab383799f358
ToppCellIPF-Stromal-SMC|IPF / Disease state, Lineage and Cell class

PDGFRB SYNM DES AEBP1 CDH6

1.18e-041881135e98b24c0de41285f01f7ac194ff0a1b59fd5c333
ToppCellPericytes-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

PDGFRB DES NKD1 AEBP1 CDH6

1.18e-04188113514c1c88a944c66f2eaac1ce7526815dcce1f5147
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B CFAP299 CDH3 WWC1 FAM149A

1.21e-0418911357659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

UNC13B ANO9 CDH3 WWC1 FAM149A

1.27e-04191113505731ece7867659c662f952812805f947032fe10
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLIPR1 F5 TLR8 HCK CACNA2D3

1.27e-0419111355d6ef70cc15ec5e983a953e547e40f9c06e355fb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 DNAH7 ITPR3 CDH3 CACNA2D3

1.27e-0419111355a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

UNC13B ANO9 CFAP299 BMPR1B CDH3

1.27e-04191113563aa671837b79d2feb7ed1e67712cc01caf72bef
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 DNAH7 ITPR3 CDH3 CACNA2D3

1.27e-04191113555ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GLIPR1 GABRG3 PDGFRB BMPR1B AEBP1

1.30e-0419211354022f208eb5db760abd0aac782a25e8ab63efc64
Druglamotrigine

UGT1A5 GRIN2C GRIN2D RYR3 ITPR3 UGT1A3 CACNA2D4 SCN4A CACNA2D3

6.47e-091161139CID000003878
Druggabapentin

GABRG3 GRID1 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 SCN4A CACNA2D3 GABRA3

1.25e-0816911310CID000003446
Drugriluzole

GABRG3 GRID1 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 SCN4A CACNA2D3 GABRA3

1.65e-0817411310CID000005070
Drugbaclofen

GABRG3 GRIN2C GRIN2D RYR3 ITPR3 BLMH CACNA2D4 CACNA2D3 GABRA3

4.80e-071911139CID000002284
Drugpropofol

GABRG3 UGT1A5 GRIN2C GRIN2D RYR3 UGT1A3 SCN4A GABRA3

5.11e-061911138CID000004943
Drugketamine

GABRG3 PRRG2 STK36 GRID1 GRIN2C GRIN2D F5 SCN4A GABRA3

6.49e-062621139CID000003821
Drugnimodipine

GABRG3 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 CACNA2D3

8.08e-061451137CID000004497
DrugH-Ni

ABCC1 UGT1A5 UGT1A3 PRKDC

1.07e-05281134CID000445665
Drugloperamide

GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 CACNA2D3

1.41e-051051136CID000003954
DrugAC1L9E0Q

ABCC1 UGT1A5 UGT1A3 KCNH5

1.43e-05301134CID000443095
Drugindole-2-carboxylic acid

UGT1A5 GRIN2C GRIN2D UGT1A3

1.86e-05321134CID000072899
DrugEAB 515

STK36 GRIN2C GRIN2D

1.91e-05111133CID000159489
Drughomocysteic acid

EPHB2 SYNM GRIN2C GRIN2D F5

1.93e-05661135CID000092117
Druggallopamil

NBN RYR3 ITPR3 CACNA2D4 CACNA2D3

2.08e-05671135CID000001234
DrugCNS 1145

RYR3 ITPR3 CACNA2D4 CACNA2D3

2.11e-05331134CID000190902
DrugIHC-64

RYR3 ITPR3 CACNA2D4 CACNA2D3

2.11e-05331134CID000162753
DrugAC1L2AC7

RYR3 ITPR3 CACNA2D4 HPS1 CACNA2D3

2.40e-05691135CID000068733
Drugnitrosamine

ABCC1 SYNM UGT1A5 BLMH UGT1A3

2.58e-05701135CID000037183
Drugfelbamate

GABRG3 GRID1 GRIN2C GRIN2D GABRA3

2.58e-05701135CID000003331
Drugfluo-3

ABCC1 GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4

3.31e-051221136CID000104978
DrugNSC7524

GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 SCN4A CACNA2D3

3.52e-051821137CID000005657
Drug2-amino-3-phosphonopropionic acid

GRID1 GRIN2C GRIN2D GRHL1 HPS1

3.84e-05761135CID000003857
DrugDHPN

ABCC1 SYNM BLMH HPS1

4.14e-05391134CID000040828
Drugharmol

ABCC1 STK36 UGT1A5 UGT1A3

4.58e-05401134CID000068094
DrugDE gel

GABRG3 NBN GRID1 GRIN2C GRIN2D CACNA2D4

8.04e-051431136CID000008146
DrugNBQX

GABRG3 GRID1 GRIN2C GRIN2D CACNA2D4

8.65e-05901135CID003272523
DrugDantrolene-13C3

GRIN2C GRIN2D RYR3 ITPR3 CACNA2D4 CACNA2D3

8.68e-051451136CID000002951
Diseaseodorant-binding protein 2b measurement

OBP2B OBP2A

1.39e-0451112EFO_0801859
Diseaseprimary ciliary dyskinesia (is_implicated_in)

STK36 DNAH7

2.08e-0461112DOID:9562 (is_implicated_in)
Diseaseamino acid measurement

EPHB2 GABRG3 LARP1 CHIT1 DNAH7 RYR3 GRHL1 SCN4A JAZF1 PRKDC

2.47e-0467811110EFO_0005134
Diseaseepilepsy (implicated_via_orthology)

UNC13B GRIN2C GRIN2D SCN4A KCNH5

3.87e-041631115DOID:1826 (implicated_via_orthology)
DiseaseX-11793--oxidized bilirubin measurement

UGT1A5 UGT1A3

3.87e-0481112EFO_0021260
DiseaseSuccinimide measurement

UGT1A5 UGT1A3

3.87e-0481112EFO_0022118
DiseaseX-11530 measurement

UGT1A5 UGT1A3

3.87e-0481112EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A5 UGT1A3

3.87e-0481112EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A5 UGT1A3

3.87e-0481112EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A5 UGT1A3

3.87e-0481112EFO_0800696
DiseaseX-10458 measurement

UGT1A5 UGT1A3

3.87e-0481112EFO_0800692
DiseaseX-24849 measurement

UGT1A5 UGT1A3

3.87e-0481112EFO_0800909
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A5 UGT1A3

3.87e-0481112EFO_0802740
DiseaseX-16946 measurement

UGT1A5 UGT1A3

3.87e-0481112EFO_0800766
DiseaseX-11442 measurement

UGT1A5 UGT1A3

4.96e-0491112EFO_0021236
DiseaseX-11441 measurement

UGT1A5 UGT1A3

4.96e-0491112EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A5 UGT1A3

4.96e-0491112EFO_0004739
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A5 UGT1A3

4.96e-0491112EFO_0801037
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A5 UGT1A3

4.96e-0491112EFO_0801036
DiseaseX-11880 measurement

UGT1A5 UGT1A3

4.96e-0491112EFO_0800698
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A5 UGT1A3

4.96e-0491112EFO_0020691
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A5 UGT1A3

4.96e-0491112EFO_0802127
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A5 UGT1A3

4.96e-0491112EFO_0004570, GO_0009410
Diseasebilirubin measurement, response to tenofovir

UGT1A5 UGT1A3

6.19e-04101112EFO_0004570, EFO_0009279
DiseaseX-21448 measurement

UGT1A5 UGT1A3

6.19e-04101112EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A5 UGT1A3

6.19e-04101112EFO_0802185
DiseaseX-23974 measurement

UGT1A5 UGT1A3

6.19e-04101112EFO_0800867
DiseaseGastric Adenocarcinoma

PDGFRB BMPR1A BMPR1B

6.55e-04451113C0278701
Diseasehistidine betaine (hercynine) measurement

UGT1A5 UGT1A3

7.54e-04111112EFO_0800972
DiseaseX-21796 measurement

UGT1A5 UGT1A3

7.54e-04111112EFO_0800825
Diseaseinsomnia, bilirubin measurement

UGT1A5 UGT1A3

7.54e-04111112EFO_0004570, EFO_0004698
Diseasealdosterone measurement

UGT1A5 UGT1A3

7.54e-04111112EFO_0010219
Diseasep-cresol glucuronide measurement

UGT1A5 UGT1A3

9.03e-04121112EFO_0800079
Diseasebiliverdin measurement

UGT1A5 UGT1A3

9.03e-04121112EFO_0021033
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

BMPR1A BMPR1B

1.06e-03131112DOID:0050787 (implicated_via_orthology)
Diseaseretinol dehydrogenase 16 measurement

UGT1A5 UGT1A3

1.06e-03131112EFO_0802007
DiseaseKuhnt-Junius degeneration (is_marker_for)

PDGFRB IGF1R

1.24e-03141112DOID:10873 (is_marker_for)
Diseaseprostate carcinoma, type 2 diabetes mellitus

GRHL1 JAZF1 KNL1

1.44e-03591113EFO_0001663, MONDO_0005148
Diseaseinterferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement

PDGFRB F5

1.63e-03161112EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
DiseaseEye Abnormalities

BMPR1A BMPR1B

1.84e-03171112C0015393
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A5 UGT1A3

1.84e-03171112EFO_0004611, EFO_0007800
Diseaseangiopoietin-related protein 1 measurement

UGT1A5 UGT1A3

2.06e-03181112EFO_0801382
DiseaseProstate cancer, familial

EPHB2 NBN KNL1

2.27e-03691113C2931456
DiseaseCongenital hernia of foramen of Morgagni

DES IGF1R

2.30e-03191112C0265699
DiseaseCongenital hernia of foramen of Bochdalek

DES IGF1R

2.30e-03191112C0265700
DiseaseFetal Growth Retardation

DES IGF1R

2.55e-03201112C0015934
Diseaseautism spectrum disorder (implicated_via_orthology)

PDGFRB ITPR3 EIF4E1B GPRASP2

2.64e-031521114DOID:0060041 (implicated_via_orthology)
DiseaseCongenital diaphragmatic hernia

DES IGF1R

2.81e-03211112C0235833
Diseasetissue factor measurement

UGT1A5 UGT1A3

2.81e-03211112EFO_0010623
Diseasepeak expiratory flow

GRID1 IGF1R INF2 SCN4A JAZF1 FKBP4 CACNA2D3

2.81e-034981117EFO_0009718
DiseaseLung diseases

IGF1R HPS1 PRKDC

3.21e-03781113C0024115

Protein segments in the cluster

PeptideGeneStartEntry
TLTTYAISWTQDEFD

UGT1A3

76

P35503
FSSQIYDEEATWELR

BTNL3

116

Q6UXE8
KSWYIADIFTDESED

ANKRD11

1111

Q6UB99
SAHAEATYEEDWEVF

CTDSPL2

241

Q05D32
AGWEESETETYTEVV

AEBP1

1076

Q8IUX7
CETEASEQWDYVLVA

ANO9

26

A1A5B4
TEEASWFRETEIYQT

BMPR1B

236

O00238
VSETLQEIYSSEWDG

BIN2

81

Q9UBW5
EEDSRQEWTFTLYDF

NKD1

131

Q969G9
WLDTFVSSYEQFLDV

NBEAL1

26

Q6ZS30
FVEYDKNSDDTVTWD

RCN2

106

Q14257
EYLSIEYSEEEVWLT

ITPR3

681

Q14573
LSTTEWNDETLYQEF

CHIT1

66

Q13231
EEFYVDLETKETVWQ

HLA-DQA2

56

P01906
NTFTAWSDEESDYEI

LARP1

621

Q6PKG0
SSAITNWYDEIQDYD

GLIPR1

111

P48060
SEFSNWYTEALQDEE

MAGEB10

301

Q96LZ2
VYSWRDDEFDEASSQ

FAM149A

266

A5PLN7
SWRYEETSENEAVAE

WWC1

841

Q8IX03
VDTVEDFWALYSHIQ

EIF4E1B

91

A6NMX2
AHTVDFYTESVWEEL

METTL25

36

Q8N6Q8
EEHDSYSDQVWSIDE

KIAA1109

3061

Q2LD37
EVDYEESDSDESWTT

JAZF1

136

Q86VZ6
IWYSIGDYEVIDEVT

KCNH5

366

Q8NCM2
FSAADVYVPDEWEVA

IGF1R

981

P08069
DYTSFNTVDEWLEAI

EPHB2

911

P29323
DVVEWSDDQAVFTFV

KNL1

2136

Q8NG31
EYTIDVFFRQTWHDE

GABRA3

111

P34903
EVAIYFSDEEWEVLT

POGK

51

Q9P215
LSFTLEEEDITGTWY

OBP2A

16

Q9NY56
WSRDFSDEEQSVVYV

KIAA1328

16

Q86T90
SSWYVDASDVLTTED

INF2

1076

Q27J81
YEQAADAELAWVAET

MACF1

5676

Q9UPN3
FWEESSYEELDDVTS

MEI1

806

Q5TIA1
ENIEVYHEFWFEEAT

THAP12

526

O43422
SWTFEHLVYQVEVSE

DCHS2

1081

Q6V1P9
YSLTDWIEFEEIADL

PCF11

1386

O94913
LSFTLEEEDITGTWY

OBP2B

16

Q9NPH6
RSWEQTYEEEIFLSS

EFCAB5

701

A4FU69
NYVARVDSLETEEWF

HCK

131

P08631
IEEIAYNAISFTWDI

GRHL1

351

Q9NZI5
NVATEETVFYALESW

KLHL28

191

Q9NXS3
IYGTNSEWETFDVTD

BMP10

191

O95393
EYQIDIFFAQTWTDS

GABRG3

91

Q99928
QEHDVVWTEAYIDST

CACNA2D3

446

Q8IZS8
YNSVDLSEVEWEDQA

CACNA2D4

586

Q7Z3S7
YETIAAKNISEAEEW

DES

281

P17661
EWDAVEFVIHSYRET

DNAH7

911

Q8WXX0
TEEASWFRETEIYQT

BMPR1A

266

P36894
TDEWFSEYVYEVVVD

BLMH

411

Q13867
WDVAVVEYAALTDDD

GRID1

741

Q9ULK0
LYELWEEYETQSSAE

HDDC2

121

Q7Z4H3
VTTDADQDYDYLSDW

CDH6

756

P55285
SEETQTLVREYFSWE

EEF1G

406

P26641
IVSWLEYESSFSNEE

FKBP4

296

Q02790
AWFTEEDLDLVTLYF

ENPP7

181

Q6UWV6
AEVLFYWTDQEFEES

HPS1

11

Q92902
QETDEEFDARWVTYF

COX5A

46

P20674
TFEESVSNYSEWAVF

DSEL

21

Q8IZU8
VSNYSEWAVFTDDID

DSEL

26

Q8IZU8
AQLTDDSDIYWTAEV

CDH3

581

P22223
NTFTDWSDNDSDYEI

LARP1B

426

Q659C4
EEESQLETNVTYWEE

PDGFRB

471

P09619
LETNVTYWEEEQEFE

PDGFRB

476

P09619
TYWEEEQEFEVVSTL

PDGFRB

481

P09619
FSQYSDEEVWTSLEL

ABCC1

1391

P33527
DIFLDWESYQFRTEE

UTP20

1161

O75691
WESYQFRTEEIDAVF

UTP20

1166

O75691
ETFETKVDDYSQEWA

POLR1A

1161

O95602
ATNDTFDWDAYISDE

SCN4A

331

P35499
LFADYLQSEVWDSEE

TBC1D25

666

Q3MII6
VAESWRETVQLYEDE

SYNM

191

O15061
EEESTIRYSWQDEIV

SYNM

856

O15061
AEEISWDYSEFVQRE

F5

1586

P12259
TTYVADTESEQADTW

NBN

361

O60934
YESIEYWNTSVQEDV

PTCHD1

561

Q96NR3
FSEVQEKASDWEYTI

KIFC3

556

Q9BVG8
WEYTITVSAAEIYNE

KIFC3

566

Q9BVG8
FESESEDEFYKQSWV

GPRASP2

326

Q96D09
WYSDQDFESEFVEVL

POLR3F

166

Q9H1D9
FYEDTNSWIEDTEFL

SI

721

P14410
TCSITVEENEWVVDY

NOP2

516

P46087
KVVDWEESTEVTLYF

STK36

751

Q9NRP7
TDISFYNWDADIAVS

CFAP299

156

Q6V702
VEEQYEESFWICVAS

CLRN2

181

A0PK11
ESEFIDSQRVWAEYA

PRPF8

1376

Q6P2Q9
VSSLDWQVYFAEEPE

PRSS53

521

Q2L4Q9
YDTKDASVTDWVINE

TLR8

886

Q9NR97
EDVAVYFSQEEWELL

ZNF132

41

P52740
LTEAEWEDLTQQYYS

TTLL8

296

A6PVC2
EEEAIYFSAEKQWEV

STIM2

576

Q9P246
WIETEEYSFEEKLVQ

RYR3

3516

Q15413
FEDNTLTERFWESYI

PRRG2

81

O14669
FEDVAIYFSQEEWEL

ZNF551

31

Q7Z340
TLTTYAISWTQDEFD

UGT1A5

76

P35504
DDAWKVYFDETAQEI

UNC13B

771

O14795
INSITDIYETEEEGW

UBE2U

271

Q5VVX9
DFVWLHDTLIETTDY

SNX5

71

Q9Y5X3
YNDISVTESSWEEVE

USP28

616

Q96RU2
VTESSWEEVERDSYG

USP28

621

Q96RU2
TSAVEQERWDEDSFY

YLPM1

1566

P49750
LSECEFQEYTIDSDW

PRKDC

2581

P78527
VTFDDITVYLLQEEW

ZNF862

11

O60290
TFEDVAVYFSQEEWR

ZNF773

16

Q6PK81
TFEDVAVYFSEEEWQ

ZNF75D

236

P51815
VVFEDVAIYFSQEEW

ZNF547

11

Q8IVP9
FEDVTIYFSQEEWVL

ZNF792

16

Q3KQV3
TSAYEDYDIVIWSAT

UBLCP1

171

Q8WVY7
EYDSESSQQWRELEE

TRAPPC8

701

Q9Y2L5
YWRTESEEEEENASL

PHF8

821

Q9UPP1
FEDVAIYFSQEEWEL

ZNF530

16

Q6P9A1
DVAVDFTREEWDQLY

ZNF713

36

Q8N859
TWEAEVELATETVYV

GTF3C1

866

Q12789
VELATETVYVDDASW

GTF3C1

871

Q12789
VTFEDVAVEFTQEEW

ZNF557

36

Q8N988
EDSNVWHDISDFLVY

PXMP4

191

Q9Y6I8
DVFVYFSQEEWVLLD

ZNF772

31

Q68DY9
WYEFDDQSVTEVSES

USP33

686

Q8TEY7
TFDSVAVEFTQEEWT

ZNF560

111

Q96MR9
TFAYHQEEIDVWTEE

ZC3H7B

501

Q9UGR2
VLEEYDWSAFAVITS

GRIN2C

156

Q14957
FEVLEEYDWTSFVAV

GRIN2D

176

O15399