Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL3A1 FBLN1 FBLN2 FBN1 FBN2 VWF LAMA3 LTBP1 LTBP4 SSPOP FBN3	1.51e-09	188	95	11	GO:0005201
GeneOntologyMolecularFunction	integrin binding	COL3A1 FBLN1 FBN1 VWF ITGA5 LTBP4 ITGB6	2.03e-05	175	95	7	GO:0005178
GeneOntologyMolecularFunction	extracellular matrix constituent conferring elasticity	FBLN2 FBN1 FBN2	2.22e-05	12	95	3	GO:0030023
GeneOntologyMolecularFunction	cell adhesion molecule binding	COL3A1 FLNA FBLN1 FASN FBN1 VWF MACF1 ROBO3 ITGA5 LTBP4 TENM2 ITGB6	2.69e-05	599	95	12	GO:0050839
GeneOntologyMolecularFunction	structural molecule activity conferring elasticity	FBLN2 FBN1 FBN2	3.66e-05	14	95	3	GO:0097493
GeneOntologyMolecularFunction	calcium ion binding	FBLN1 THBD CAMKK2 FBLN2 FBN1 FBN2 MACF1 LTBP1 ITGA5 LTBP4 TENM2 FBN3 NOTCH4	5.37e-05	749	95	13	GO:0005509
GeneOntologyMolecularFunction	structural molecule activity	COL3A1 FBLN1 FBLN2 FBN1 FBN2 VWF EPB41L4B LAMA3 MACF1 LTBP1 LTBP4 SSPOP FBN3	3.00e-04	891	95	13	GO:0005198
GeneOntologyBiologicalProcess	sequestering of TGFbeta in extracellular matrix	FBN1 FBN2 LTBP1	3.65e-07	4	94	3	GO:0035583
GeneOntologyBiologicalProcess	wound healing	VANGL2 COL3A1 FLNA FBLN1 THBD VWF EPB41L4B ANO6 MACF1 ITGA5 ITGB6 NOTCH4	2.46e-06	493	94	12	GO:0042060
GeneOntologyBiologicalProcess	maintenance of protein location in extracellular region	FBN1 FBN2 LTBP1	5.05e-06	8	94	3	GO:0071694
GeneOntologyBiologicalProcess	maintenance of protein location	FLNA FBN1 FBN2 LTBP1 NR5A1 MDFI	1.24e-05	112	94	6	GO:0045185
GeneOntologyBiologicalProcess	sequestering of extracellular ligand from receptor	FBN1 FBN2 LTBP1	1.47e-05	11	94	3	GO:0035581
GeneOntologyBiologicalProcess	extracellular regulation of signal transduction	FBN1 FBN2 LTBP1	2.54e-05	13	94	3	GO:1900115
GeneOntologyBiologicalProcess	extracellular negative regulation of signal transduction	FBN1 FBN2 LTBP1	2.54e-05	13	94	3	GO:1900116
GeneOntologyBiologicalProcess	response to wounding	VANGL2 COL3A1 FLNA FBLN1 THBD VWF EPB41L4B ANO6 MACF1 ITGA5 ITGB6 NOTCH4	4.47e-05	659	94	12	GO:0009611
GeneOntologyBiologicalProcess	blood coagulation, fibrin clot formation	FLNA FBLN1 THBD	5.95e-05	17	94	3	GO:0072378
GeneOntologyBiologicalProcess	activation of blood coagulation via clotting cascade	VWF ANO6	6.15e-05	3	94	2	GO:0002543
GeneOntologyBiologicalProcess	cell-substrate adhesion	COL3A1 FLNA FBLN1 FBLN2 VWF PTPRK MACF1 ITGA5 ITGB6	1.06e-04	410	94	9	GO:0031589
GeneOntologyBiologicalProcess	cellular response to transforming growth factor beta stimulus	COL3A1 PPARGC1A FBN1 FBN2 PTPRK LTBP1 LTBP4 ITGB6	1.51e-04	336	94	8	GO:0071560
GeneOntologyBiologicalProcess	protein activation cascade	FLNA FBLN1 THBD	1.73e-04	24	94	3	GO:0072376
GeneOntologyBiologicalProcess	response to transforming growth factor beta	COL3A1 PPARGC1A FBN1 FBN2 PTPRK LTBP1 LTBP4 ITGB6	1.73e-04	343	94	8	GO:0071559
GeneOntologyBiologicalProcess	integrin-mediated signaling pathway	COL3A1 FLNA FBLN1 ITGA5 ITGB6	2.59e-04	124	94	5	GO:0007229
GeneOntologyBiologicalProcess	transforming growth factor beta receptor signaling pathway	COL3A1 FBN1 FBN2 PTPRK LTBP1 LTBP4 ITGB6	2.70e-04	276	94	7	GO:0007179
GeneOntologyBiologicalProcess	positive regulation of hemostasis	THBD VWF ANO6	3.76e-04	31	94	3	GO:1900048
GeneOntologyBiologicalProcess	positive regulation of blood coagulation	THBD VWF ANO6	3.76e-04	31	94	3	GO:0030194
GeneOntologyCellularComponent	microfibril	FBN1 FBN2 LTBP1 LTBP4 FBN3	2.18e-09	13	95	5	GO:0001527
GeneOntologyCellularComponent	extracellular matrix	COL3A1 TRIL FBLN1 FBLN2 FBN1 FBN2 VWF OTOGL LAMA3 LTBP1 CPZ LTBP4 SSPOP FBN3	1.53e-06	656	95	14	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL3A1 TRIL FBLN1 FBLN2 FBN1 FBN2 VWF OTOGL LAMA3 LTBP1 CPZ LTBP4 SSPOP FBN3	1.59e-06	658	95	14	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL3A1 FBLN1 FBLN2 FBN1 FBN2 VWF LAMA3 LTBP1 LTBP4 SSPOP	1.48e-04	530	95	10	GO:0062023
GeneOntologyCellularComponent	supramolecular fiber	COL3A1 GRIP1 FLNA FBLN1 FBN1 FBN2 KLHL21 ARFGEF2 MACF1 LTBP1 LZTS2 LTBP4 PBXIP1 FBN3	8.62e-04	1179	95	14	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	COL3A1 GRIP1 FLNA FBLN1 FBN1 FBN2 KLHL21 ARFGEF2 MACF1 LTBP1 LZTS2 LTBP4 PBXIP1 FBN3	9.20e-04	1187	95	14	GO:0099081
GeneOntologyCellularComponent	MCM complex	MCM9 MCM4	1.09e-03	11	95	2	GO:0042555
MousePheno	overexpanded pulmonary alveolus	FBLN1 FBN1 LTBP4 ITGB6	4.90e-05	37	77	4	MP:0001183
MousePheno	emphysema	FLNA FBN1 LTBP4 ITGB6	4.90e-05	37	77	4	MP:0001958
MousePheno	abnormal lung morphology	VANGL2 COL3A1 TNK1 PPARGC1A FLNA FBLN1 THBD FBN1 RARB SPEG LAMA3 MCM4 LTBP4 ITGB6	6.64e-05	767	77	14	MP:0001175
MousePheno	abnormal embryonic tissue morphology	VANGL2 GRIP1 EFL1 FBLN1 THBD SBDS GAS1 MACF1 FGD5 LTBP1 NR5A1 LZTS2 MDFI ALDH1A3 ROBO3 ITGA5 CXXC1	9.55e-05	1116	77	17	MP:0002085
MousePheno	abnormal ulna morphology	FBN1 FBN2 ANO6 LTBP1 PBXIP1	9.78e-05	84	77	5	MP:0005108
MousePheno	abnormal respiratory system morphology	VANGL2 COL3A1 TNK1 PPARGC1A FLNA FBLN1 THBD FBN1 RARB SPEG GAS1 LAMA3 MCM4 ALDH1A3 LTBP4 ITGB6	1.23e-04	1027	77	16	MP:0002132
Domain	cEGF	FBLN1 THBD FBLN2 FBN1 FBN2 LTBP1 FBN3	3.97e-11	26	94	7	PF12662
Domain	cEGF	FBLN1 THBD FBLN2 FBN1 FBN2 LTBP1 FBN3	3.97e-11	26	94	7	IPR026823
Domain	TB	FBN1 FBN2 LTBP1 LTBP4 FBN3	6.04e-11	7	94	5	PF00683
Domain	-	FBN1 FBN2 LTBP1 LTBP4 FBN3	1.60e-10	8	94	5	3.90.290.10
Domain	TB_dom	FBN1 FBN2 LTBP1 LTBP4 FBN3	3.60e-10	9	94	5	IPR017878
Domain	TB	FBN1 FBN2 LTBP1 LTBP4 FBN3	3.60e-10	9	94	5	PS51364
Domain	EGF_CA	FBLN1 THBD FBLN2 FBN1 FBN2 LTBP1 LTBP4 FBN3 NOTCH4	4.69e-10	86	94	9	PF07645
Domain	EGF_1	FBLN1 THBD FBLN2 FBN1 FBN2 LAMA3 LTBP1 LTBP4 SSPOP TENM2 ITGB6 FBN3 NOTCH4	4.76e-10	255	94	13	PS00022
Domain	EGF_CA	FBLN1 THBD FBLN2 FBN1 FBN2 LTBP1 LTBP4 TENM2 FBN3 NOTCH4	5.54e-10	122	94	10	SM00179
Domain	EGF-like_Ca-bd_dom	FBLN1 THBD FBLN2 FBN1 FBN2 LTBP1 LTBP4 TENM2 FBN3 NOTCH4	6.51e-10	124	94	10	IPR001881
Domain	EGF_2	FBLN1 THBD FBLN2 FBN1 FBN2 LAMA3 LTBP1 LTBP4 SSPOP TENM2 ITGB6 FBN3 NOTCH4	7.63e-10	265	94	13	PS01186
Domain	EGF_Ca-bd_CS	FBLN1 THBD FBLN2 FBN1 FBN2 LTBP1 LTBP4 FBN3 NOTCH4	1.39e-09	97	94	9	IPR018097
Domain	EGF_CA	FBLN1 THBD FBLN2 FBN1 FBN2 LTBP1 LTBP4 FBN3 NOTCH4	1.67e-09	99	94	9	PS01187
Domain	ASX_HYDROXYL	FBLN1 THBD FBLN2 FBN1 FBN2 LTBP1 LTBP4 FBN3 NOTCH4	1.83e-09	100	94	9	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBLN1 THBD FBLN2 FBN1 FBN2 LTBP1 LTBP4 FBN3 NOTCH4	3.08e-09	106	94	9	IPR000152
Domain	Growth_fac_rcpt_	FBLN1 THBD FBLN2 FBN1 FBN2 LAMA3 LTBP1 LTBP4 FBN3 NOTCH4	6.13e-09	156	94	10	IPR009030
Domain	EGF-like_CS	FBLN1 THBD FBLN2 FBN1 FBN2 LAMA3 LTBP1 LTBP4 TENM2 ITGB6 FBN3 NOTCH4	7.45e-09	261	94	12	IPR013032
Domain	EGF	FBLN1 THBD FBLN2 FBN1 FBN2 LAMA3 LTBP1 LTBP4 TENM2 FBN3 NOTCH4	2.73e-08	235	94	11	SM00181
Domain	EGF_3	FBLN1 THBD FBLN2 FBN1 FBN2 LTBP1 LTBP4 SSPOP TENM2 FBN3 NOTCH4	2.73e-08	235	94	11	PS50026
Domain	EGF-like_dom	FBLN1 THBD FBLN2 FBN1 FBN2 LAMA3 LTBP1 LTBP4 TENM2 FBN3 NOTCH4	4.94e-08	249	94	11	IPR000742
Domain	FBN	FBN1 FBN2 FBN3	1.23e-07	3	94	3	IPR011398
Domain	hEGF	FBN2 FBN3 NOTCH4	3.69e-04	28	94	3	PF12661
Domain	-	KMT2C RNFT2 LONRF1 ZNRF1 RNF41 FGD5 MIB2 SH3RF3 CXXC1	4.33e-04	449	94	9	3.30.40.10
Domain	Znf_RING/FYVE/PHD	KMT2C RNFT2 LONRF1 ZNRF1 RNF41 FGD5 MIB2 SH3RF3 CXXC1	5.07e-04	459	94	9	IPR013083
Domain	ANATO	FBLN1 FBLN2	5.18e-04	7	94	2	SM00104
Domain	ANAPHYLATOXIN_2	FBLN1 FBLN2	5.18e-04	7	94	2	PS01178
Domain	ANAPHYLATOXIN_1	FBLN1 FBLN2	5.18e-04	7	94	2	PS01177
Domain	ANATO	FBLN1 FBLN2	5.18e-04	7	94	2	PF01821
Domain	Anaphylatoxin/fibulin	FBLN1 FBLN2	5.18e-04	7	94	2	IPR000020
Domain	Death	THOC1 IRAK2 TNFRSF1A	6.04e-04	33	94	3	PF00531
Domain	MCM_OB	MCM9 MCM4	6.88e-04	8	94	2	PF17207
Domain	MCM_OB	MCM9 MCM4	6.88e-04	8	94	2	IPR033762
Domain	MCM_2	MCM9 MCM4	6.88e-04	8	94	2	PS50051
Domain	MCM_1	MCM9 MCM4	6.88e-04	8	94	2	PS00847
Domain	ZF_RING_2	KMT2C RNFT2 LONRF1 ZNRF1 RNF41 MIB2 SH3RF3	7.68e-04	298	94	7	PS50089
Domain	VWFC_1	COL3A1 VWF SSPOP	7.82e-04	36	94	3	PS01208
Domain	RING	KMT2C RNFT2 LONRF1 ZNRF1 RNF41 MIB2 SH3RF3	8.80e-04	305	94	7	SM00184
Domain	MCM	MCM9 MCM4	8.82e-04	9	94	2	SM00350
Domain	MCM_dom	MCM9 MCM4	8.82e-04	9	94	2	IPR001208
Domain	MCM	MCM9 MCM4	8.82e-04	9	94	2	IPR031327
Domain	MCM	MCM9 MCM4	8.82e-04	9	94	2	PF00493
Domain	VWFC_2	COL3A1 VWF SSPOP	9.17e-04	38	94	3	PS50184
Domain	Death_domain	THOC1 IRAK2 TNFRSF1A	9.17e-04	38	94	3	IPR000488
Domain	VWC	COL3A1 VWF SSPOP	9.17e-04	38	94	3	SM00214
Domain	DEATH_DOMAIN	THOC1 IRAK2 TNFRSF1A	9.17e-04	38	94	3	PS50017
Domain	VWF_dom	COL3A1 VWF SSPOP	1.23e-03	42	94	3	IPR001007
Domain	Znf_RING	KMT2C RNFT2 LONRF1 ZNRF1 RNF41 MIB2 SH3RF3	1.29e-03	326	94	7	IPR001841
Domain	C8	VWF SSPOP	1.60e-03	12	94	2	PF08742
Domain	TIL	VWF SSPOP	1.60e-03	12	94	2	PF01826
Domain	Unchr_dom_Cys-rich	VWF SSPOP	1.89e-03	13	94	2	IPR014853
Domain	C8	VWF SSPOP	1.89e-03	13	94	2	SM00832
Domain	TIL_dom	VWF SSPOP	2.19e-03	14	94	2	IPR002919
Domain	VWF_type-D	VWF SSPOP	2.87e-03	16	94	2	IPR001846
Domain	VWFD	VWF SSPOP	2.87e-03	16	94	2	PS51233
Domain	VWD	VWF SSPOP	2.87e-03	16	94	2	SM00216
Domain	VWD	VWF SSPOP	2.87e-03	16	94	2	PF00094
Domain	CarboxyPept-like_regulatory	CPZ TENM2	3.24e-03	17	94	2	IPR008969
Domain	ZF_RING_1	RNFT2 LONRF1 ZNRF1 RNF41 MIB2 SH3RF3	3.52e-03	291	94	6	PS00518
Domain	CTCK_1	VWF SSPOP	3.64e-03	18	94	2	PS01185
Domain	EGF	THBD LTBP1 FBN3 NOTCH4	3.77e-03	126	94	4	PF00008
Domain	VWC_out	VWF SSPOP	4.05e-03	19	94	2	SM00215
Domain	-	EFL1 GALK2	4.95e-03	21	94	2	3.30.230.10
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBLN1 FBLN2 FBN1 FBN2 LTBP1 ITGA5 LTBP4 ITGB6 FBN3	1.12e-12	44	74	9	M26969
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBLN1 FBLN2 FBN1 FBN2 LTBP1 LTBP4 ITGB6 FBN3	1.34e-11	37	74	8	M27134
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBLN2 FBN1 FBN2 LTBP1 ITGA5 LTBP4 ITGB6	1.11e-09	39	74	7	MM14601
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBLN2 FBN1 FBN2 LTBP1 LTBP4 ITGB6	1.38e-08	32	74	6	MM14854
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL3A1 FBLN1 FBLN2 FBN1 FBN2 VWF LAMA3 LTBP1 ITGA5 LTBP4 ITGB6 FBN3	4.68e-08	300	74	12	M610
Pathway	WP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE	FLNA FBN1 FBN2 LTBP1 FBN3	1.70e-07	25	74	5	M39713
Pathway	KEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA	FBN1 LTBP1 LTBP4	7.63e-06	8	74	3	M47850
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL3A1 FBLN2 FBN1 FBN2 VWF LTBP1 ITGA5 LTBP4 ITGB6	7.85e-06	258	74	9	MM14572
Pathway	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS	FBN1 LTBP1 LTBP4 ITGB6	4.51e-05	38	74	4	MM14874
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL3A1 FBN1 VWF ITGA5 ITGB6	4.80e-05	76	74	5	MM14867
Pathway	WP_FOCAL_ADHESION	COL3A1 TNK1 FLNA VWF LAMA3 ITGA5 ITGB6	5.49e-05	187	74	7	MM15913
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	COL3A1 VWF LAMA3 ITGA5 ITGB6	7.77e-05	84	74	5	M7098
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL3A1 FBN1 VWF ITGA5 ITGB6	8.22e-05	85	74	5	M16441
Pathway	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS	FBN1 LTBP1 LTBP4 ITGB6	1.05e-04	47	74	4	M646
Pathway	PID_INTEGRIN1_PATHWAY	COL3A1 FBN1 LAMA3 ITGA5	3.94e-04	66	74	4	M18
Pathway	KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY	PRKAG3 PPARGC1A CAMKK2 TNFRSF1A	4.18e-04	67	74	4	M10462
Pathway	WP_FOCAL_ADHESION	TNK1 FLNA VWF LAMA3 ITGA5 ITGB6	6.13e-04	199	74	6	M39402
Pathway	KEGG_FOCAL_ADHESION	COL3A1 FLNA VWF LAMA3 ITGA5 ITGB6	6.13e-04	199	74	6	M7253
Pathway	REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX	FBN1 LTBP1 LTBP4 ITGB6	7.09e-04	77	74	4	MM14670
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL3A1 FBN1 FBN2 LAMA3 FBN3	8.36e-04	140	74	5	M587
Pathway	WP_GENETIC_CAUSES_OF_PORTOSINUSOIDAL_VASCULAR_DISEASE	EFL1 SBDS NOTCH4	9.49e-04	37	74	3	M45513
Pubmed	Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.	FBN1 FBN2 LTBP1 LTBP4	5.22e-11	4	95	4	12429738
Pubmed	Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.	FBLN2 FBN1 LTBP1 LTBP4	7.80e-10	6	95	4	19349279
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL3A1 FBLN2 FBN1 FBN2 VWF LAMA3 LTBP1 LTBP4 SSPOP	1.36e-09	175	95	9	28071719
Pubmed	Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.	FBLN1 FBN1 FBN2 VWF	6.51e-09	9	95	4	12122015
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	COL3A1 FBLN1 FBLN2 FBN1 VWF LAMA3 LTBP1 LTBP4	7.10e-09	146	95	8	27068509
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL3A1 FBLN1 FBLN2 FBN1 VWF LAMA3 LTBP1 LTBP4	2.04e-08	167	95	8	22159717
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	GRIP1 FLNA FBLN1 FBLN2 FBN1 VWF LTBP1 GRIP2 LZTS2 MDFI LTBP4 CXXC1	4.39e-08	560	95	12	21653829
Pubmed	Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves.	COL3A1 FLNA FBLN1 RARB ALDH1A3	5.56e-08	37	95	5	38011284
Pubmed	Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner.	COL3A1 FLNA FBLN1 RARB ALDH1A3	5.56e-08	37	95	5	20236931
Pubmed	Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.	FBN1 FBN2 FBN3	7.88e-08	4	95	3	25034023
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL3A1 FBLN1 FBN1 FBN2 VWF LTBP1 LTBP4	9.44e-08	135	95	7	28675934
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	COL3A1 FBLN1 FBLN2 FBN1 FBN2 LTBP1	1.40e-07	86	95	6	28327460
Pubmed	POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.	FBN1 FBN2 LTBP1	1.97e-07	5	95	3	34411563
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	COL3A1 FBLN1 FBLN2 FBN1 VWF LTBP1 LTBP4	2.22e-07	153	95	7	25037231
Pubmed	Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.	COL3A1 FBLN2 FBN1 FBN2 ITGA5	2.63e-07	50	95	5	23658023
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FLNA KMT2C FASN LONRF1 KLHL21 SPEG NOB1 ARFGEF2 ZNRF1 FRMD8 MIB2 MDFI ITGA5 LTBP4 CRAMP1	3.17e-07	1105	95	15	35748872
Pubmed	alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity.	FBN1 ITGA5 ITGB6	3.93e-07	6	95	3	17158881
Pubmed	Adamts18 modulates the development of the aortic arch and common carotid artery.	COL3A1 FBN1 FBN2 LAMA3	7.46e-07	26	95	4	34189436
Pubmed	EMILIN proteins are novel extracellular constituents of the dentin-pulp complex.	FBLN1 FBLN2 FBN1	1.09e-06	8	95	3	32948785
Pubmed	ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.	COL3A1 FBN1 FBN2 LTBP1	1.36e-06	30	95	4	32882513
Pubmed	Heritable Thoracic Aortic Disease Overview	COL3A1 FLNA FBN1 FBN2	1.36e-06	30	95	4	20301299
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	LRP12 FBN1 FBN2 SSPOP PBXIP1	1.54e-06	71	95	5	33541421
Pubmed	Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues.	FBN1 FBN2 LTBP1	1.64e-06	9	95	3	38844137
Pubmed	Limb- and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia.	COL3A1 FBN1 FBN2	2.34e-06	10	95	3	30738849
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	COL3A1 LRP12 FBLN1 FBN1 EMC1 FBN2 PTPRK ANO6 GAS1 ARFGEF2 LTBP1 TNFRSF1A ITGA5 PBXIP1	4.79e-06	1201	95	14	35696571
Pubmed	Mapping Extracellular Protein-Protein Interactions Using Extracellular Proximity Labeling (ePL).	COL3A1 FLNA SETDB2 FBLN1 FBN1 FBN2 LTBP1	5.44e-06	247	95	7	39238192
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	COL3A1 FBLN1 FBLN2 FBN1 VWF LTBP1 LTBP4	5.58e-06	248	95	7	24006456
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	FBLN1 FBLN2 LTBP1 GRIP2 LZTS2 MDFI LTBP4 SSPOP CXXC1 PBXIP1	6.60e-06	608	95	10	16713569
Pubmed	Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.	FBN1 FBN2	7.38e-06	2	95	2	12399449
Pubmed	Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.	FBN1 FBN2	7.38e-06	2	95	2	21851253
Pubmed	Confocal laser scanning analysis of the association of fibulin-2 with fibrillin-1 and fibronectin define different stages of skin regeneration.	FBLN2 FBN1	7.38e-06	2	95	2	9886271
Pubmed	New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.	FBN1 FBN2	7.38e-06	2	95	2	30044367
Pubmed	The interaction of von Willebrand factor-A1 domain with collagen: mutation G1324S (type 2M von Willebrand disease) impairs the conformational change in A1 domain induced by collagen.	COL3A1 VWF	7.38e-06	2	95	2	16420575
Pubmed	Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.	FBN1 FBN2	7.38e-06	2	95	2	21440062
Pubmed	MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.	FBN1 FBN2	7.38e-06	2	95	2	15131124
Pubmed	Fibulin-1 and fibulin-2 expression during organogenesis in the developing mouse embryo.	FBLN1 FBLN2	7.38e-06	2	95	2	8850569
Pubmed	A single high-affinity binding site for von Willebrand factor in collagen III, identified using synthetic triple-helical peptides.	COL3A1 VWF	7.38e-06	2	95	2	16912226
Pubmed	The glutamate receptor-interacting protein family of GluR2-binding proteins is required for long-term synaptic depression expression in cerebellar Purkinje cells.	GRIP1 GRIP2	7.38e-06	2	95	2	18509036
Pubmed	Microfibril structure masks fibrillin-2 in postnatal tissues.	FBN1 FBN2	7.38e-06	2	95	2	20404337
Pubmed	The N-Terminal Region of Fibrillin-1 Mediates a Bipartite Interaction with LTBP1.	FBN1 LTBP1	7.38e-06	2	95	2	28669633
Pubmed	Thrombomodulin and von Willebrand factor: relation to endothelial dysfunction and disease outcome in children with acute lymphoblastic leukemia.	THBD VWF	7.38e-06	2	95	2	21150180
Pubmed	Fibrillln mutations in Marfan syndrome and related phenotypes.	FBN1 FBN2	7.38e-06	2	95	2	8791520
Pubmed	Identification of a Novel ITGαvβ6-Binding Peptide Using Protein Separation and Phage Display.	ITGA5 ITGB6	7.38e-06	2	95	2	28468949
Pubmed	Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.	FBN1 FBN2	7.38e-06	2	95	2	8307578
Pubmed	Defective Guanine Nucleotide Exchange in the Elongation Factor-like 1 (EFL1) GTPase by Mutations in the Shwachman-Diamond Syndrome Protein.	EFL1 SBDS	7.38e-06	2	95	2	25991726
Pubmed	Mechanism of eIF6 release from the nascent 60S ribosomal subunit.	EFL1 SBDS	7.38e-06	2	95	2	26479198
Pubmed	Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.	FBN1 FBN2	7.38e-06	2	95	2	7744963
Pubmed	The Von Willebrand Factor A1-Collagen III Interaction Is Independent of Conformation and Type 2 Von Willebrand Disease Phenotype.	COL3A1 VWF	7.38e-06	2	95	2	27889474
Pubmed	Fibrillin microfibrils in bone physiology.	FBN1 FBN2	7.38e-06	2	95	2	26408953
Pubmed	Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.	FBN1 FBN2	7.38e-06	2	95	2	18006876
Pubmed	Gain-of-function R225Q mutation in AMP-activated protein kinase gamma3 subunit increases mitochondrial biogenesis in glycolytic skeletal muscle.	PRKAG3 PPARGC1A	7.38e-06	2	95	2	18838377
Pubmed	Prognostic value of plasma levels of thrombomodulin and von Willebrand factor in Egyptian children with acute lymphoblastic leukemia.	THBD VWF	7.38e-06	2	95	2	24243921
Pubmed	Overlapping expression of ARFGEF2 and Filamin A in the neuroependymal lining of the lateral ventricles: insights into the cause of periventricular heterotopia.	FLNA ARFGEF2	7.38e-06	2	95	2	16320251
Pubmed	The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy.	ITGA5 ITGB6	7.38e-06	2	95	2	31259422
Pubmed	Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.	FBN1 FBN2	7.38e-06	2	95	2	24833718
Pubmed	Purkinje cell-specific Grip1/2 knockout mice show increased repetitive self-grooming and enhanced mGluR5 signaling in cerebellum.	GRIP1 GRIP2	7.38e-06	2	95	2	31476380
Pubmed	Fibrillin-1 and fibulin-2 interact and are colocalized in some tissues.	FBLN2 FBN1	7.38e-06	2	95	2	8702639
Pubmed	Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.	FBN1 FBN2	7.38e-06	2	95	2	24265020
Pubmed	In vivo studies of mutant fibrillin-1 microfibrils.	FBN1 FBN2	7.38e-06	2	95	2	20529844
Pubmed	The extracellular matrix proteins fibulin-1 and fibulin-2 in the early human embryo.	FBLN1 FBLN2	7.38e-06	2	95	2	8737292
Pubmed	Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.	FBN1 FBN2	7.38e-06	2	95	2	23133647
Pubmed	Kynurenines and oxidative status are independently associated with thrombomodulin and von Willebrand factor levels in patients with end-stage renal disease.	THBD VWF	7.38e-06	2	95	2	19477487
Pubmed	Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.	FBN1 FBN2	7.38e-06	2	95	2	1852206
Pubmed	Expression of ECM proteins fibulin-1 and -2 in acute and chronic liver disease and in cultured rat liver cells.	FBLN1 FBLN2	7.38e-06	2	95	2	19609566
Pubmed	Disruption of glutamate receptor-interacting protein in nucleus accumbens enhances vulnerability to cocaine relapse.	GRIP1 GRIP2	7.38e-06	2	95	2	24126453
Pubmed	Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.	FBN1 FBN2	7.38e-06	2	95	2	12429739
Pubmed	Evidence that the primary binding site of von Willebrand factor that mediates platelet adhesion on subendothelium is not collagen.	COL3A1 VWF	7.38e-06	2	95	2	2839553
Pubmed	Fibulin-1c regulates transforming growth factor-β activation in pulmonary tissue fibrosis.	FBLN1 LTBP1	7.38e-06	2	95	2	31343988
Pubmed	Mice lacking GRIP1/2 show increased social interactions and enhanced phosphorylation at GluA2-S880.	GRIP1 GRIP2	7.38e-06	2	95	2	28063882
Pubmed	Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.	FBN1 FBN2	7.38e-06	2	95	2	12524050
Pubmed	Inhibition of human immunodeficiency virus type 1 infection in macrophages by an alpha-v integrin blocking antibody.	ITGA5 ITGB6	7.38e-06	2	95	2	16473416
Pubmed	Interaction of the GTPase Elongation Factor Like-1 with the Shwachman-Diamond Syndrome Protein and Its Missense Mutations.	EFL1 SBDS	7.38e-06	2	95	2	30545121
Pubmed	Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.	FBN1 FBN2	7.38e-06	2	95	2	8120105
Pubmed	The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.	FBN1 FBN2	7.38e-06	2	95	2	35419902
Pubmed	Fibrillin assembly: dimer formation mediated by amino-terminal sequences.	FBN1 FBN2	7.38e-06	2	95	2	10504303
Pubmed	Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients.	FBN1 FBN3	7.38e-06	2	95	2	15221638
Pubmed	Integrin alphavbeta6 promotes tumor tolerance in colorectal cancer.	ITGA5 ITGB6	7.38e-06	2	95	2	21913024
Pubmed	Expression of fatty acid synthase is regulated by PGC‑1α and contributes to increased cell proliferation.	PPARGC1A FASN	7.38e-06	2	95	2	29130104
Pubmed	Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.	FBN1 FBN2	7.38e-06	2	95	2	25524144
Pubmed	Role of membrane cholesterol in platelet calcium signalling in response to VWF and collagen under stasis and flow.	COL3A1 VWF	7.38e-06	2	95	2	18521510
Pubmed	GRIP1 and 2 regulate activity-dependent AMPA receptor recycling via exocyst complex interactions.	GRIP1 GRIP2	7.38e-06	2	95	2	20956289
Pubmed	Different susceptibilities of fibulin-1 and fibulin-2 to cleavage by matrix metalloproteinases and other tissue proteases.	FBLN1 FBLN2	7.38e-06	2	95	2	8841408
Pubmed	Fibrillins 1 and 2 perform partially overlapping functions during aortic development.	FBN1 FBN2	7.38e-06	2	95	2	16407178
Pubmed	N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.	FBN1 FBN2	7.38e-06	2	95	2	10359653
Pubmed	Congenital Diaphragmatic Hernia Overview	COL3A1 FBN1 RARB LTBP4	7.81e-06	46	95	4	20301533
Pubmed	Role of LTBP4 in alveolarization, angiogenesis, and fibrosis in lungs.	COL3A1 VWF LTBP4	8.77e-06	15	95	3	28684544
Pubmed	ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.	COL3A1 FBN1 FBN2	1.56e-05	18	95	3	39040056
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	FBLN1 FBN1 VWF LTBP1 LTBP4	1.87e-05	118	95	5	21078624
Pubmed	Interaction of tropoelastin with the amino-terminal domains of fibrillin-1 and fibrillin-2 suggests a role for the fibrillins in elastic fiber assembly.	FBN1 FBN2	2.21e-05	3	95	2	10825173
Pubmed	Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.	FBN1 FBN2	2.21e-05	3	95	2	30201140
Pubmed	Valves of the deep venous system: an overlooked risk factor.	THBD VWF	2.21e-05	3	95	2	19436051
Pubmed	GRIP1 is required for homeostatic regulation of AMPAR trafficking.	GRIP1 GRIP2	2.21e-05	3	95	2	26216979
Pubmed	Glucocorticoids down-regulate the extracellular matrix proteins fibronectin, fibulin-1 and fibulin-2 in bone marrow stroma.	FBLN1 FBLN2	2.21e-05	3	95	2	11737251
Pubmed	Whole-Exome Sequencing in a South American Cohort Links ALDH1A3, FOXN1 and Retinoic Acid Regulation Pathways to Autism Spectrum Disorders.	RARB ALDH1A3	2.21e-05	3	95	2	26352270
Pubmed	The association of human fibulin-1 with elastic fibers: an immunohistological, ultrastructural, and RNA study.	FBLN1 FBN1	2.21e-05	3	95	2	7534784
Pubmed	TNF is a key mediator of septic encephalopathy acting through its receptor, TNF receptor-1.	FBN1 TNFRSF1A	2.21e-05	3	95	2	17884256
Pubmed	Lack of endothelial cell apoptosis in the dermis of tight skin 1 and tight skin 2 mice.	COL3A1 FBN1	2.21e-05	3	95	2	10088787
Pubmed	The expression of von Willebrand factor, soluble thrombomodulin, and soluble p-selectin during orthotopic liver transplantation.	THBD VWF	2.21e-05	3	95	2	17275499
Pubmed	Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation.	FBN1 FBN2	2.21e-05	3	95	2	20855508
Pubmed	Gain-of-function glutamate receptor interacting protein 1 variants alter GluA2 recycling and surface distribution in patients with autism.	GRIP1 GRIP2	2.21e-05	3	95	2	21383172
Interaction	ZNF408 interactions	FASN FBLN2 FBN1 FBN2 LTBP1 LZTS2 MDFI LTBP4 CXXC1	2.55e-08	145	94	9	int:ZNF408
Interaction	ATN1 interactions	KMT2C FBLN1 FBLN2 NUP43 LTBP1 MDFI LTBP4 SSPOP CXXC1	2.27e-07	187	94	9	int:ATN1
Interaction	ZFP41 interactions	FBLN1 FASN FBN1 FBN2 LTBP1 LTBP4	2.62e-07	57	94	6	int:ZFP41
Interaction	DEFB125 interactions	FBLN1 FBN2 LAMA3 MIB2	2.03e-06	20	94	4	int:DEFB125
Interaction	FBN1 interactions	FBLN2 FBN1 FBN2 NUP43 LTBP1	3.93e-06	51	94	5	int:FBN1
Interaction	MFAP5 interactions	FBLN1 FBN1 FBN2 VWF LTBP4	4.33e-06	52	94	5	int:MFAP5
Interaction	NTN5 interactions	FBN1 FBN2 LTBP1 LTBP4	4.39e-06	24	94	4	int:NTN5
Interaction	ELN interactions	FBLN1 FBLN2 FBN1 FBN2	9.64e-06	29	94	4	int:ELN
Interaction	FBLN2 interactions	FBLN1 FBLN2 FBN1 NUP43 LTBP1	1.42e-05	66	94	5	int:FBLN2
Interaction	RAC1 interactions	VANGL2 FLNA FASN EMC1 VWF ARHGAP23 EPB41L4B ANO6 MACF1 FGD5 LZTS2 TNFRSF1A MDFI ITGA5 LTBP4 SH3RF3	3.03e-05	1063	94	16	int:RAC1
Interaction	TIMP2 interactions	COL3A1 FLNA SETDB2 FBLN1 FBN1 FBN2 LTBP1 ITGA5	4.62e-05	277	94	8	int:TIMP2
Interaction	LTBP1 interactions	FASN FBLN2 FBN1 FBN2 LTBP1	7.08e-05	92	94	5	int:LTBP1
Interaction	ODAPH interactions	FBN1 LTBP1 MDFI LTBP4	8.01e-05	49	94	4	int:ODAPH
Interaction	GRM7 interactions	GRIP1 FLNA NUP43	9.02e-05	19	94	3	int:GRM7
Cytoband	Ensembl 112 genes in cytogenetic band chr3p25	FBLN2 IRAK2 FGD5 GRIP2	3.13e-04	155	95	4	chr3p25
GeneFamily	Latent transforming growth factor beta binding proteins	LTBP1 LTBP4	7.60e-05	4	65	2	628
GeneFamily	Fibulins	FBLN1 FBLN2	3.51e-04	8	65	2	556
GeneFamily	MCM family	MCM9 MCM4	4.51e-04	9	65	2	1085
GeneFamily	Ring finger proteins	RNFT2 LONRF1 ZNRF1 RNF41 SH3RF3	3.08e-03	275	65	5	58
Coexpression	NABA_ECM_GLYCOPROTEINS	FBLN1 FBLN2 FBN1 FBN2 VWF OTOGL LAMA3 LTBP1 LTBP4 SSPOP	1.97e-09	191	95	10	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	FBLN1 FBLN2 FBN1 FBN2 VWF LAMA3 LTBP1 LTBP4 SSPOP FBN3	2.53e-09	196	95	10	M3008
Coexpression	NABA_CORE_MATRISOME	COL3A1 FBLN1 FBLN2 FBN1 FBN2 VWF OTOGL LAMA3 LTBP1 LTBP4 SSPOP	4.11e-09	270	95	11	MM17057
Coexpression	NABA_CORE_MATRISOME	COL3A1 FBLN1 FBLN2 FBN1 FBN2 VWF LAMA3 LTBP1 LTBP4 SSPOP FBN3	4.97e-09	275	95	11	M5884
Coexpression	HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	COL3A1 FLNA FBLN1 FBLN2 FBN1 FBN2 GAS1 LAMA3 ITGA5	4.88e-08	200	95	9	M5930
Coexpression	DESCARTES_FETAL_THYMUS_STROMAL_CELLS	COL3A1 FBLN1 FBLN2 FBN1 FBN2 GAS1 LTBP4	6.88e-07	137	95	7	M40313
Coexpression	AIZARANI_LIVER_C29_MVECS_2	COL3A1 THBD FBLN2 VWF ARHGAP23 FGD5 ITGA5 LTBP4 NOTCH4	2.10e-06	313	95	9	M39128
Coexpression	SESTO_RESPONSE_TO_UV_C8	FASN FBN2 PTPRK LAMA3 LTBP1	6.06e-06	71	95	5	M2948
Coexpression	GAO_LARGE_INTESTINE_ADULT_CJ_IMMUNE_CELLS	COL3A1 FLNA FBLN1 THBD FBN1 VWF FGD5 ALDH1A3 ITGA5 NOTCH4	1.51e-05	505	95	10	M39167
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	GRIP1 PPARGC1A LRP12 PTPRK ARHGAP23 LONRF1 SPEG LAMA3 ZNRF1 GRIP2 GRIN3A IRGQ SSPOP TENM2	4.40e-05	1106	95	14	M39071
Coexpression	HE_LIM_SUN_FETAL_LUNG_C3_OMD_POS_ENDOTHELIAL_CELL	COL3A1 PRUNE2 RGMB FBLN1 FBLN2 FBN2 SPEG LTBP4	4.57e-05	355	95	8	M45758
Coexpression	ZHU_CMV_ALL_DN	COL3A1 FLNA FBLN1 GAS1 TNFRSF1A	7.41e-05	119	95	5	M14555
Coexpression	GSE21546_WT_VS_SAP1A_KO_DP_THYMOCYTES_DN	LRP12 THBD LONRF1 KLHL21 POLR2D KLHL35	7.44e-05	193	95	6	M7544
Coexpression	HU_FETAL_RETINA_FIBROBLAST	COL3A1 FLNA FBLN1 FBN1 FBN2 RARB ITGA5 LTBP4	8.05e-05	385	95	8	M39264
Coexpression	HE_LIM_SUN_FETAL_LUNG_C3_ARTERIAL_ENDOTHELIAL_CELL	COL3A1 RGMB FBLN2 FBN1 LTBP1 GRIP2 LTBP4	8.34e-05	286	95	7	M45746
Coexpression	GSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP	TRIL FBN2 CPZ MDFI PBXIP1 NOTCH4	8.81e-05	199	95	6	M9345
Coexpression	RUBENSTEIN_SKELETAL_MUSCLE_FBN1_FAP_CELLS	COL3A1 FBLN1 FBLN2 FBN1 GAS1 ALDH1A3 LTBP4	8.90e-05	289	95	7	M41750
Coexpression	GSE14308_TH2_VS_TH1_DN	CHAT FGD5 MIB2 GRIN3A RFESD NOTCH4	9.05e-05	200	95	6	M3360
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_30H_UP	COL3A1 FASN EPB41L4B NR5A1 TNFRSF1A LTBP4	9.05e-05	200	95	6	M9649
Coexpression	GSE7831_CPG_VS_INFLUENZA_STIM_PDC_4H_UP	ZMAT3 RGMB EMC1 EPB41L4B SBDS ITGB6	9.05e-05	200	95	6	M6958
Coexpression	TRAVAGLINI_LUNG_ADVENTITIAL_FIBROBLAST_CELL	COL3A1 FBLN1 FBLN2 FBN1 GAS1 ALDH1A3 LTBP4	1.03e-04	296	95	7	M41675
Coexpression	HAY_BONE_MARROW_STROMAL	COL3A1 FBLN1 FBN1 EPB41L4B OTOGL GAS1 TNFRSF1A MDFI ALDH1A3 TENM2 ITGB6	1.05e-04	767	95	11	M39209
Coexpression	GSE13522_WT_VS_IFNG_KO_SKING_T_CRUZI_Y_STRAIN_INF_UP	FBLN2 PLA2G3 PELI3 ZNRF1 NOTCH4	1.09e-04	129	95	5	M2911
Coexpression	DI_MARTINO_MATRISOME_HIGHLY_PROLIFERATIVE_HNSCC	FBLN2 FBN2 LTBP1	1.27e-04	27	95	3	M47994
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	FLNA RGMB LRP12 THBD EMC1 PTPRK ARHGAP23 ANO6 LTBP1 ITGA5	1.82e-04	681	95	10	M5314
Coexpression	TABULA_MURIS_SENIS_BLADDER_BLADDER_CELL_AGEING	THBD FBLN2 KLHL21 SBDS GAS1 TNFRSF1A LTBP4	2.09e-04	332	95	7	MM3679
Coexpression	CHICAS_RB1_TARGETS_CONFLUENT	COL3A1 FLNA RGMB FBLN1 FBN1 FBN2 MCM4 ALDH1A3 ITGA5	2.20e-04	567	95	9	M2129
Coexpression	WEIGEL_OXIDATIVE_STRESS_RESPONSE	MCM4 ITGA5 ITGB6	2.33e-04	33	95	3	M14591
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	FLNA RGMB LRP12 THBD EMC1 PTPRK ARHGAP23 ANO6 LTBP1 ITGA5	2.35e-04	703	95	10	MM1055
Coexpression	FAN_EMBRYONIC_CTX_ASTROCYTE_2	TRIL KMT2C FBLN1 MACF1 PBXIP1	2.48e-04	154	95	5	M39034
Coexpression	ZHU_CMV_24_HR_DN	COL3A1 FLNA GAS1 TNFRSF1A	2.50e-04	84	95	4	M4065
Coexpression	ONDER_CDH1_SIGNALING_VIA_CTNNB1	PRUNE2 FBN1 EPB41L4B LTBP1	2.50e-04	84	95	4	M15484
Coexpression	CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN	COL3A1 FBN1 LTBP1	2.78e-04	35	95	3	M11788
Coexpression	NABA_MATRISOME	COL3A1 FBLN1 CBLN3 FBLN2 FBN1 FBN2 VWF OTOGL LAMA3 LTBP1 LTBP4 SSPOP	2.84e-04	1008	95	12	MM17056
Coexpression	SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER	THBD FBN1 LAMA3 KLHL35	2.99e-04	88	95	4	M11288
Coexpression	CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN	COL3A1 FBN1 LTBP1	3.02e-04	36	95	3	MM1212
Coexpression	MULLIGHAN_NPM1_SIGNATURE_3_DN	CAMKK2 EMC1 RNFT2 ITGA5 LTBP4	3.05e-04	161	95	5	M15047
Coexpression	NABA_MATRISOME	COL3A1 FBLN1 CBLN3 FBLN2 FBN1 FBN2 VWF LAMA3 LTBP1 LTBP4 SSPOP FBN3	3.34e-04	1026	95	12	M5889
Coexpression	ONDER_CDH1_TARGETS_2_UP	COL3A1 PRUNE2 FBLN1 FBN1 RNFT2 LTBP1	3.52e-04	257	95	6	M13867
Coexpression	MURARO_PANCREAS_ENDOTHELIAL_CELL	THBD VWF ARHGAP23 MACF1 FRMD8 ITGA5 NOTCH4	3.53e-04	362	95	7	M39176
CoexpressionAtlas	Stromal Cells, BEC.MLN, gp38- CD31+, Lymph Node, avg-5	THBD FBLN2 VWF PTPRK ARHGAP23 LAMA3 FGD5 ITGA5 LTBP4 NOTCH4	3.75e-05	456	95	10	GSM777032_500
CoexpressionAtlas	Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3	COL3A1 FBLN1 FBN1 LTBP1 LTBP4	7.51e-05	97	95	5	GSM777043_100
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	COL3A1 TRIL FLNA FBLN1 THBD FBN1 FBN2 LTBP4	7.62e-05	310	95	8	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	COL3A1 TRIL PPARGC1A FLNA FBLN1 FBLN2 FBN1 FBN2 RARB MCM4 LTBP1 NR5A1 ME2	7.89e-05	827	95	13	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000	COL3A1 TRIL FLNA FBLN1 FBN1 FBN2 RARB LTBP1	1.36e-04	337	95	8	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	COL3A1 TRIL PPARGC1A FLNA FBLN1 THBD CAMKK2 FBLN2 FBN1 FBN2 NR5A1 LTBP4	1.61e-04	768	95	12	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#5_top-relative-expression-ranked_1000	VWF SPEG FGD5 GRIN3A NOTCH4	1.61e-04	114	95	5	gudmap_developingKidney_e11.5_metaneph mesench_1000_k5
CoexpressionAtlas	Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3	COL3A1 RGMB FBLN1 THBD FBLN2 FBN1 GAS1 LTBP1 LTBP4	1.72e-04	445	95	9	GSM777043_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500	COL3A1 PPARGC1A FLNA THBD FBLN2 FBN1 NR5A1 LTBP4	2.29e-04	364	95	8	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_1000	THOC1 GRIP1 TNK1 ZMAT3 PPARGC1A PTPRK LONRF1 MCM9 LAMA3 SLC5A9 GRIN3A TENM2	2.34e-04	800	95	12	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_1000	COL3A1 FBLN1 FBN2 RARB LTBP1 GRIN3A	2.45e-04	195	95	6	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k4
CoexpressionAtlas	JC_fibro_top-relative-expression-ranked_2500_k-means-cluster#5	COL3A1 ZMAT3 RGMB FBLN1 CBLN3 FBLN2 FBN1 SPEG GAS1 RNF41 CPZ SH3RF3	2.74e-04	814	95	12	JC_fibro_2500_K5
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	COL3A1 PPARGC1A FBLN1 FBLN2 FBN1 GAS1 LTBP1 ALDH1A3 ROBO3	2.39e-10	185	95	9	506eee2c1b6e8acec3aa8b2c66868010006c4c14
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 FBLN2 FBN1 ARHGAP23 FGD5 LTBP1 GRIP2 LTBP4 NOTCH4	2.76e-10	188	95	9	ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBLN2 FBN1 VWF KLHL35 FGD5 LTBP1 ALDH1A3 ITGA5 NOTCH4	2.90e-10	189	95	9	c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBLN2 FBN1 VWF FGD5 LTBP1 ALDH1A3 ITGA5 LTBP4 NOTCH4	3.03e-10	190	95	9	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 FBLN2 FBN1 LAMA3 FGD5 LTBP1 ITGA5 LTBP4 NOTCH4	3.18e-10	191	95	9	b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ ALDH1A3 LTBP4	3.49e-10	193	95	9	e27885a9e1a2a3e165c5366d4cfcda05c5454483
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL3A1 FBLN1 FBLN2 FBN1 FBN2 GAS1 CPZ ALDH1A3 LTBP4	4.00e-10	196	95	9	eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCell	distal-1-mesenchymal\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ ALDH1A3 LTBP4	4.78e-10	200	95	9	7623f82bd85a0ff7e2097e9281551208dfc602a8
ToppCell	distal-mesenchymal-Adventitial_Fibroblast-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ ALDH1A3 LTBP4	4.78e-10	200	95	9	56e838787385dd282caadeac24fbb0a706bf7f2b
ToppCell	distal-1-mesenchymal-Adventitial_Fibroblast\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ ALDH1A3 LTBP4	4.78e-10	200	95	9	738060ed65fa5473fdb39e686f7cdecc059ed92c
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ ALDH1A3 LTBP4	4.78e-10	200	95	9	6b48ddde83bc6c941d557844aa214d4d2c8e736d
ToppCell	distal-mesenchymal-Adventitial_Fibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ ALDH1A3 LTBP4	4.78e-10	200	95	9	687cfada2d0977e8985e0a73a5804f84f2ca9c52
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 TRIL FBLN1 FBLN2 FBN1 GAS1 LTBP1 LTBP4	5.53e-09	182	95	8	d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	5.77e-09	183	95	8	63294d66e3ccf152ffe5d1237106764c14390b62
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	5.77e-09	183	95	8	7e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 FBLN1 FBLN2 FBN1 GAS1 ALDH1A3 ROBO3 LTBP4	7.13e-09	188	95	8	c32d023a69b6da79687ff8fa7485e7499db57046
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 FBLN1 FBLN2 FBN1 GAS1 ALDH1A3 ROBO3 LTBP4	7.13e-09	188	95	8	1cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBLN2 FBN1 VWF FGD5 ALDH1A3 ITGA5 LTBP4 NOTCH4	7.43e-09	189	95	8	b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCell	IPF-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	GRIP1 FBLN1 ARHGAP23 LAMA3 MDFI LTBP4 ITGB6 NOTCH4	7.75e-09	190	95	8	4f15842b424eefadbfe451875e517cf70e29607f
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FBLN1 FBLN2 FBN1 FBN2 GAS1 CPZ LTBP4	8.07e-09	191	95	8	4b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FBLN1 FBLN2 FBN1 FBN2 GAS1 CPZ LTBP4	8.07e-09	191	95	8	75d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 FBLN1 FBLN2 FBN1 GAS1 CPZ ALDH1A3 LTBP4	8.07e-09	191	95	8	24dc77ee8de01b42559f92721655f4281b114e17
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBLN2 FBN1 VWF FGD5 LTBP1 ALDH1A3 LTBP4 NOTCH4	8.07e-09	191	95	8	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIL THBD FBLN2 VWF LAMA3 FGD5 LTBP1 LTBP4	8.41e-09	192	95	8	f4cd65e6c5b17bcabf45fe5b687246c72e7975f7
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL3A1 FBLN1 FBLN2 FBN1 GAS1 GRIP2 ALDH1A3 LTBP4	8.41e-09	192	95	8	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FBLN1 FBLN2 FBN1 FBN2 GAS1 LTBP1 LTBP4	8.41e-09	192	95	8	8937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	8.41e-09	192	95	8	7b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FBLN1 FBLN2 FBN1 FBN2 GAS1 LTBP1 LTBP4	8.41e-09	192	95	8	e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 FBLN1 FBN1 RARB GAS1 LTBP1 CPZ LTBP4	8.41e-09	192	95	8	df1545670370fb1010c567cd059c2783eab315f7
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIL THBD FBLN2 VWF LAMA3 FGD5 LTBP1 LTBP4	8.41e-09	192	95	8	bcd8876235be503186f119653b39476488c0fa15
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FBLN1 FBLN2 FBN1 FBN2 GAS1 LTBP1 LTBP4	8.41e-09	192	95	8	ac1477433704573f95111eee6263b93668d2845e
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	8.41e-09	192	95	8	32acd89617934016cd135d2cc797e8e79ae1b37f
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 ALDH1A3 LTBP4	8.41e-09	192	95	8	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THBD FBLN2 FBN1 VWF FGD5 ITGA5 LTBP4 NOTCH4	8.76e-09	193	95	8	0b328f725f6feba263783eaca60c142e80df90f3
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 FBLN1 THBD FBLN2 FBN1 GAS1 LTBP1 LTBP4	8.76e-09	193	95	8	25248b8e65d558b1a96a87c93e3e5b4c0ba168fe
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 FBLN1 THBD FBLN2 FBN1 GAS1 LTBP1 LTBP4	8.76e-09	193	95	8	f1f1097204e07a7bed416425b8256942038a734f
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 FBLN1 FBLN2 FBN1 GAS1 CPZ ALDH1A3 LTBP4	9.12e-09	194	95	8	5594f7437448cb4b37d2d100f44d30c4a367df26
ToppCell	facs-MAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FBLN1 THBD FBLN2 FBN1 GAS1 LTBP1 LTBP4	9.12e-09	194	95	8	f906b090f67df4cfe3498cdbb52cc0efa08e06cc
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	9.12e-09	194	95	8	c9e589fe7df6a9b377654581a2aebb607cbb03b9
ToppCell	facs-MAT-Fat-18m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FBLN1 THBD FBLN2 FBN1 GAS1 LTBP1 LTBP4	9.12e-09	194	95	8	944cdb0403d80a10a2eea2a3516a9343dbccc32c
ToppCell	facs-GAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FBLN1 THBD FBLN2 FBN1 GAS1 LTBP1 LTBP4	9.12e-09	194	95	8	9709dc95fb6982b6a0467b507845d5bc17252e3e
ToppCell	facs-GAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FBLN1 THBD FBLN2 FBN1 GAS1 LTBP1 LTBP4	9.12e-09	194	95	8	93b7a9065430740ec31fce4e8c14ffccb498591d
ToppCell	facs-GAT-Fat-18m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FBLN1 THBD FBLN2 FBN1 GAS1 LTBP1 LTBP4	9.12e-09	194	95	8	0d2e65b44e3f143971c2fd24c4552f042b049cfa
ToppCell	facs-MAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FBLN1 THBD FBLN2 FBN1 GAS1 LTBP1 LTBP4	9.12e-09	194	95	8	85081d255fcc1e9854c0073321dd9f0feaa48866
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 FLNA FBLN1 FBN1 RARB LTBP1 LTBP4 SH3RF3	9.49e-09	195	95	8	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 FBLN1 FBN1 RARB LONRF1 LTBP1 LTBP4 SH3RF3	9.49e-09	195	95	8	cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 FBLN1 FBN1 RARB LONRF1 LTBP1 LTBP4 SH3RF3	9.49e-09	195	95	8	783bfa8110161cbd6def50ce849cae676c39c458
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 FLNA FBLN1 FBN1 RARB LTBP1 LTBP4 SH3RF3	9.49e-09	195	95	8	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	PND03-Mesenchymal\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 TRIL FLNA FBLN1 FBN1 GAS1 MACF1 LTBP4	1.03e-08	197	95	8	e3053ef8f604b6892c21c03e12612b49d3d30f23
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 FBLN1 FBN1 RARB LTBP1 GRIP2 LTBP4 SH3RF3	1.03e-08	197	95	8	b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 FBLN1 FBN1 RARB LTBP1 GRIP2 LTBP4 SH3RF3	1.03e-08	197	95	8	c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBD FBLN2 VWF FGD5 LTBP1 ITGA5 LTBP4 NOTCH4	1.07e-08	198	95	8	5e781583908c4ee107d986904a646a7c6b8e3591
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Myofibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	COL3A1 FBLN1 FBLN2 FBN1 LTBP1 CPZ MDFI LTBP4	1.11e-08	199	95	8	7a227c239afdaebcac84644d9b2653a5f1a4be71
ToppCell	wk_15-18-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL3A1 FBLN1 FBLN2 FBN1 FBN2 GAS1 CPZ LTBP4	1.11e-08	199	95	8	8de6d7b2067b22cb9b5f01aa56a3803aebc4406d
ToppCell	medial-2-mesenchymal-Myofibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 TNK1 FBLN1 FBN1 SPEG LTBP1 MDFI LTBP4	1.11e-08	199	95	8	95aae608fa35a9c82b12c6f18937ce636750ca44
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	COL3A1 FBLN1 FBN1 RARB LTBP1 CPZ ALDH1A3 LTBP4	1.11e-08	199	95	8	fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 THBD FBLN2 VWF FGD5 ITGA5 LTBP4 NOTCH4	1.11e-08	199	95	8	f35e9c05d0a0339ff691b38564da7aad8e9218aa
ToppCell	distal-3-mesenchymal-Adventitial_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	1.11e-08	199	95	8	547a7c30abc730af2670aee00c7a6af60426c9ac
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	1.11e-08	199	95	8	4e128c705ad36fd840582848f278770f356fcc8b
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	1.11e-08	199	95	8	a538da095ba996ee96e263442cf5b6ba9178f3d4
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	1.11e-08	199	95	8	4032f03a4165f5f2a90ef1d8315cc743ce9075bb
ToppCell	distal-2-mesenchymal-Adventitial_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 TRIL FBLN1 FBLN2 FBN1 GAS1 CPZ LTBP4	1.11e-08	199	95	8	97b475f9110ef7bb29d9cf2109b7e43177830f05
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	1.11e-08	199	95	8	0019cfaa586a450c2e4952d1184a540561c8d0ba
ToppCell	medial-mesenchymal-Myofibroblast\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 TNK1 FBLN1 FBN1 SPEG LTBP1 MDFI LTBP4	1.11e-08	199	95	8	e25acdb5809aaff631cb06dbe4c7e59549a0bdb9
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 THBD FBLN2 VWF FGD5 ITGA5 LTBP4 NOTCH4	1.11e-08	199	95	8	33f1669eeb701986b4dec409efdb6c06c3c41c2b
ToppCell	wk_20-22-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL3A1 FBLN1 FBLN2 FBN1 GAS1 CPZ GRIP2 LTBP4	1.11e-08	199	95	8	ab0589c068c24aa989bdca083504fbad0c15221d
ToppCell	medial-mesenchymal-Myofibroblast-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 TNK1 FBLN1 FBN1 SPEG LTBP1 MDFI LTBP4	1.11e-08	199	95	8	9ebf4822ff9fa08574edec5dbf4f2a1488f34b1d
ToppCell	cellseq-Mesenchymal-Fibroblastic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL3A1 FBLN1 FBLN2 FBN1 GAS1 MACF1 LTBP1 LTBP4	1.16e-08	200	95	8	8978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCell	Biopsy_Other_PF-Mesenchymal-Fibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	1.16e-08	200	95	8	9996b6887cf2b1936e10a1aa396f09fd8da5f4c4
ToppCell	Biopsy_Control_(H.)-Mesenchymal\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	1.16e-08	200	95	8	01522ed0b68614b1ebdf190957d44a9d48a6c6e3
ToppCell	15-Airway\|15 / Age, Tissue, Lineage and Cell class	COL3A1 FBLN1 FBLN2 FBN1 FBN2 GAS1 LTBP1 LTBP4	1.16e-08	200	95	8	ba4b8d5becf81351901c2ecac74ffa28e29586f3
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	1.16e-08	200	95	8	3e6730c9ed7003a4acf501f699a4965a7a50f946
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Fibroblasts\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 ALDH1A3 LTBP4	1.16e-08	200	95	8	bfa73bc5f8a6c7de8353ca049a921ef19f7f4437
ToppCell	proximal-mesenchymal-Adventitial_Fibroblast\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	1.16e-08	200	95	8	58c5870030192b337e7d883044948634fcd17d2c
ToppCell	Biopsy_Other_PF-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	COL3A1 FBLN1 FBLN2 FBN1 LTBP1 CPZ ALDH1A3 LTBP4	1.16e-08	200	95	8	0aa316b71f195ecf17ee897e307f8928a755a637
ToppCell	proximal-mesenchymal-Adventitial_Fibroblast-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	1.16e-08	200	95	8	05486d86868f6a93429226063cca270f00dd8714
ToppCell	proximal-3-mesenchymal-Adventitial_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	1.16e-08	200	95	8	869d45b71efd395d050873db5fee2ed0443d5e6f
ToppCell	medial-mesenchymal-Adventitial_Fibroblast\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ ALDH1A3 LTBP4	1.16e-08	200	95	8	87a5a0c252c08ba10316c21f6a9d5244c4d98c74
ToppCell	Biopsy_IPF-Mesenchymal-Fibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	1.16e-08	200	95	8	d8637f1e62d3fb9476dc51e1b1dc2f4b14b5fcd8
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 ALDH1A3 LTBP4	1.16e-08	200	95	8	ef30f9b68bfdb8d947ed399603e4dd0d5ff0144d
ToppCell	tumor_Lung-Fibroblasts\|tumor_Lung / Location, Cell class and cell subclass	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 MDFI LTBP4	1.16e-08	200	95	8	073a68b5ce232203ffee86342cba2a00d907e119
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 ALDH1A3 LTBP4	1.16e-08	200	95	8	b28bfe6eb96b4db9cb27f0fc8fc39259c125f05e
ToppCell	medial-2-mesenchymal-Adventitial_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ ALDH1A3 LTBP4	1.16e-08	200	95	8	6ccf44f10d2cee5f48b8f05bd9a1b94057184d56
ToppCell	medial-mesenchymal-Adventitial_Fibroblast-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ ALDH1A3 LTBP4	1.16e-08	200	95	8	5ee1318a74ca28a81bd81c20c611de84c17636b0
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ LTBP4	1.16e-08	200	95	8	56536236a7012efdb28f85b40e464f3da3e87ce8
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 ALDH1A3 LTBP4	1.16e-08	200	95	8	87953ea65ff2a01485e13dd49d993ae6ae679cbf
ToppCell	Basal_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	VANGL2 FBLN1 ARHGAP23 MDFI ALDH1A3 LTBP4 TENM2	6.35e-08	164	95	7	85487a303194f5244956ec1ca2d1758d38117f41
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ	6.62e-08	165	95	7	4e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 CPZ	7.18e-08	167	95	7	fe3338f99f94c0dac37e3d649dfdce82e4a56022
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 GRIP1 FBLN2 GAS1 LTBP1 CPZ LTBP4	9.51e-08	174	95	7	a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 MDFI	1.07e-07	177	95	7	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 MDFI	1.07e-07	177	95	7	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	356C-Fibroblasts-Fibroblast-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 ALDH1A3	1.11e-07	178	95	7	a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell	356C-Fibroblasts-Fibroblast-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 FBLN1 FBLN2 FBN1 GAS1 LTBP1 ALDH1A3	1.11e-07	178	95	7	371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	COL3A1 PRUNE2 FLNA SPEG LTBP1 ITGA5 SH3RF3	1.20e-07	180	95	7	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FBLN1 CBLN3 FBN1 GAS1 CPZ LTBP4	1.24e-07	181	95	7	3462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FBLN1 CBLN3 FBN1 GAS1 CPZ LTBP4	1.24e-07	181	95	7	6730e249cac55ae892cc567d9211615882f3dab4
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 FBLN2 FBN1 VWF LAMA3 FGD5 LTBP4	1.29e-07	182	95	7	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 FBLN2 FBN1 VWF LAMA3 FGD5 LTBP4	1.29e-07	182	95	7	d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 FBLN1 FBLN2 FBN1 GAS1 CPZ LTBP4	1.34e-07	183	95	7	06a68fa2be36448064f4668be24a5b85ad85c6e8
Computational	ECM and collagens.	COL3A1 FBLN1 FBLN2 FBN1 VWF GAS1 LTBP1 ALDH1A3 TENM2	1.54e-06	225	54	9	MODULE_47
Computational	Intermediate filaments.	FASN FBN2 PTPRK LAMA3 ALDH1A3 TENM2	1.87e-06	75	54	6	MODULE_154
Computational	Intermediate filaments and keratins.	FASN FBN2 PTPRK LAMA3 ALDH1A3 TENM2	2.73e-06	80	54	6	MODULE_357
Computational	Genes in the cancer module 297.	FASN FBN2 PTPRK LAMA3 ALDH1A3 TENM2	2.73e-06	80	54	6	MODULE_297
Computational	Metal / Ca ion binding.	FBLN1 THBD FASN FBLN2 FBN1 FBN2 LTBP1	4.14e-06	133	54	7	MODULE_324
Computational	Adhesion molecules.	COL3A1 FBN1 FBN2 VWF LAMA3 ITGA5	7.05e-05	141	54	6	MODULE_122
Computational	Placenta genes.	COL3A1 FLNA FBLN1 FBLN2 FBN2 VWF GAS1 LTBP1 ITGA5	4.46e-04	463	54	9	MODULE_38
Computational	Ovary genes.	COL3A1 FLNA FBLN1 FBN1 VWF PTPRK GAS1 LTBP1	4.58e-04	368	54	8	MODULE_1
Computational	DRG (dorsal root ganglia) genes.	COL3A1 FLNA FBLN1 FBLN2 FBN1 VWF LTBP1 ALDH1A3	6.08e-04	384	54	8	MODULE_2
Computational	Trachea genes.	FLNA FBLN1 FBLN2 VWF PTPRK GAS1 LTBP1 ALDH1A3	1.01e-03	415	54	8	MODULE_6
Computational	Genes upregulated in subsets of cells of a given type within various tumors	THBD FBN1 ALDH1A3	1.77e-03	48	54	3	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_PI16_POS
Computational	Genes upregulated in subsets of cells of a given type within various tumors	COL3A1 FBLN1 FBN1	1.99e-03	50	54	3	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_1
Computational	Genes upregulated in subsets of cells of a given type within various tumors	THBD FBLN2 VWF	1.99e-03	50	54	3	GAVISH_3CA_METAPROGRAM_ENDOTHELIAL_HEV_2
Computational	Genes upregulated in subsets of cells of a given type within various tumors	FLNA LAMA3 ITGB6	1.99e-03	50	54	3	GAVISH_3CA_MALIGNANT_METAPROGRAM_13_EMT_2
Drug	Rgd Peptide	COL3A1 FBLN1 THBD FBN1 FBN2 VWF SPEG LAMA3 ITGA5 ITGB6 FBN3	4.87e-09	239	95	11	CID000104802
Drug	Grgds	FLNA FBLN1 FBLN2 VWF SPEG LAMA3 ITGA5	5.64e-08	83	95	7	CID000123811
Drug	Amidopyrine [58-15-1]; Down 200; 17.2uM; MCF7; HT_HG-U133A	FBLN1 EMC1 RNFT2 MACF1 ROBO3 ITGA5 LTBP4 PBXIP1	1.74e-06	197	95	8	2222_DN
Drug	Methamphetamine	COL3A1 PRUNE2 ZMAT3 PPARGC1A FLNA DIS3L ANO6 SPEG ZNRF1 IRAK2 MACF1 CHAT LTBP1 CPZ GRIP2 LZTS2 LTBP4 SH3RF3 PBXIP1	4.42e-06	1401	95	19	ctd:D008694
Drug	C2-1-Hydroxy-3-Methyl-Butyl-Thiamin	THBD VWF ITGA5	1.13e-05	11	95	3	CID011840994
Drug	Napelline [5008-52-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A	COL3A1 FBLN1 RARB MED16 SPEG LTBP4 PBXIP1	1.83e-05	196	95	7	6084_UP
Drug	SC-58125; Up 200; 10uM; MCF7; HG-U133A	MED16 SPEG LAMA3 KLHL35 CHAT RNF41 ARHGAP45	2.02e-05	199	95	7	254_UP
Drug	salta	THOC1 FBN2 SPEG	3.09e-05	15	95	3	CID000015763
Disease	connective tissue disease (implicated_via_orthology)	FBN1 FBN2 FBN3	3.03e-08	3	93	3	DOID:65 (implicated_via_orthology)
Disease	Periventricular nodular heterotopia	FLNA ARFGEF2	9.83e-06	2	93	2	cv:C1868720
Disease	Shwachman-Diamond syndrome (is_implicated_in)	EFL1 SBDS	9.83e-06	2	93	2	DOID:0060479 (is_implicated_in)
Disease	Familial thoracic aortic aneurysm and aortic dissection	COL3A1 FLNA FBN1 FBN2	2.41e-05	53	93	4	C4707243
Disease	Familial aortopathy	COL3A1 FBN1	2.94e-05	3	93	2	cv:CN078214
Disease	systemic scleroderma (implicated_via_orthology)	COL3A1 FBN1	2.94e-05	3	93	2	DOID:418 (implicated_via_orthology)
Disease	scoliosis (is_implicated_in)	FBN1 FBN2	5.87e-05	4	93	2	DOID:0060249 (is_implicated_in)
Disease	Shwachman syndrome	EFL1 SBDS	5.87e-05	4	93	2	C0272170
Disease	Shwachman syndrome	EFL1 SBDS	5.87e-05	4	93	2	cv:C0272170
Disease	type 2 diabetes mellitus (biomarker_via_orthology)	COL3A1 PPARGC1A THBD FBN1 TNFRSF1A	1.05e-04	147	93	5	DOID:9352 (biomarker_via_orthology)
Disease	periventricular nodular heterotopia (is_implicated_in)	FLNA ARFGEF2	1.46e-04	6	93	2	DOID:0050454 (is_implicated_in)
Disease	familial combined hyperlipidemia (is_marker_for)	THBD VWF	1.46e-04	6	93	2	DOID:13809 (is_marker_for)
Disease	Endometrioma	FBLN1 FBN1 RARB MED16 NR5A1	1.60e-04	161	93	5	C0269102
Disease	Endometriosis	FBLN1 FBN1 RARB MED16 NR5A1	1.60e-04	161	93	5	C0014175
Disease	Amelogenesis imperfecta local hypoplastic form	LAMA3 ITGB6	2.04e-04	7	93	2	C0399367
Disease	Shwachman-Diamond syndrome (implicated_via_orthology)	EFL1 SBDS	2.04e-04	7	93	2	DOID:0060479 (implicated_via_orthology)
Disease	Periventricular Nodular Heterotopia	FLNA ARFGEF2	2.04e-04	7	93	2	C1868720
Disease	X-linked Adrenal Hypoplasia	MCM4 NR5A1	2.72e-04	8	93	2	C0342482
Disease	mesangial proliferative glomerulonephritis (biomarker_via_orthology)	FBN1 VWF	2.72e-04	8	93	2	DOID:4783 (biomarker_via_orthology)
Disease	mitral valve prolapse (is_implicated_in)	FLNA FBN1	3.49e-04	9	93	2	DOID:988 (is_implicated_in)
Disease	Congestive heart failure	PPARGC1A FASN VWF TNFRSF1A	4.14e-04	110	93	4	C0018802
Disease	Heart failure	PPARGC1A FASN VWF TNFRSF1A	4.14e-04	110	93	4	C0018801
Disease	Left-Sided Heart Failure	PPARGC1A FASN VWF TNFRSF1A	4.14e-04	110	93	4	C0023212
Disease	Heart Failure, Right-Sided	PPARGC1A FASN VWF TNFRSF1A	4.14e-04	110	93	4	C0235527
Disease	Heart Decompensation	PPARGC1A FASN VWF TNFRSF1A	4.14e-04	110	93	4	C1961112
Disease	Myocardial Failure	PPARGC1A FASN VWF TNFRSF1A	4.14e-04	110	93	4	C1959583
Disease	end stage renal disease (is_marker_for)	THBD VWF TNFRSF1A	4.17e-04	46	93	3	DOID:783 (is_marker_for)
Disease	Liver Cirrhosis, Experimental	COL3A1 PRUNE2 FLNA THBD FBN1 VWF ANO6 LTBP1 ITGB6	7.58e-04	774	93	9	C0023893
Disease	Proteinuria	VWF RARB	1.00e-03	15	93	2	HP_0000093
Disease	respiratory symptom change measurement, response to placebo	PPARGC1A MDFI	1.30e-03	17	93	2	EFO_0008344, EFO_0010068
Disease	myocardial infarction (biomarker_via_orthology)	COL3A1 PPARGC1A VWF TNFRSF1A	1.67e-03	160	93	4	DOID:5844 (biomarker_via_orthology)
Disease	glomerulonephritis (biomarker_via_orthology)	FBN1 LTBP1	1.80e-03	20	93	2	DOID:2921 (biomarker_via_orthology)
Disease	reading and spelling ability	GALK2 ARFGEF2 SH3RF3 IZUMO3	1.91e-03	166	93	4	EFO_0005301
Disease	Malignant neoplasm of breast	FLNA FASN VWF RARB OTOGL ARFGEF2 MACF1 FGD5 LZTS2 NOTCH4	2.06e-03	1074	93	10	C0006142
Disease	Hereditary Diffuse Gastric Cancer	KMT2C THBD RARB ALDH1A3 ITGA5	2.38e-03	293	93	5	C1708349
Disease	Stomach Neoplasms	KMT2C THBD RARB ALDH1A3 ITGA5	2.52e-03	297	93	5	C0038356
Disease	serum iron measurement	ATP13A4 GALK2 NOTCH4	2.57e-03	86	93	3	EFO_0006332
Disease	systemic scleroderma (is_implicated_in)	FBN1 NOTCH4	2.59e-03	24	93	2	DOID:418 (is_implicated_in)
Disease	Malignant neoplasm of stomach	KMT2C THBD RARB ALDH1A3 ITGA5	2.63e-03	300	93	5	C0024623
Disease	cortical thickness	VANGL2 GRIP1 FBN1 GALK2 FBN2 ARFGEF2 MACF1 ME2 SH3RF3 TENM2	2.66e-03	1113	93	10	EFO_0004840
Disease	ankylosing spondylitis	FASN ANO6 TNFRSF1A	3.01e-03	91	93	3	EFO_0003898
Disease	Endogenous Hyperinsulinism	COL3A1 FBN1	3.04e-03	26	93	2	C1257963
Disease	Exogenous Hyperinsulinism	COL3A1 FBN1	3.04e-03	26	93	2	C1257964
Disease	Compensatory Hyperinsulinemia	COL3A1 FBN1	3.04e-03	26	93	2	C1257965

Protein segments in the cluster

Peptide	Gene	Start	Entry
EELEPCGTACEGLFI	VANGL2	136	Q9ULK5
VCAEELEPAAGADCK	BHLHB9	146	Q6PI77
ECELEGLLEERPALC	PRKAG3	146	Q9UGI9
PCDAVLIEGSCVVDE	ATP13A4	296	Q4VNC1
DGCIIVVDAVEGVCP	EFL1	111	Q7Z2Z2
TEPERVLGELECQEC	ARFGEF2	311	Q9Y6D5
PCIVCADADLDLAVE	ALDH1A3	286	P47895
ELDEPCAEAQCLLLL	CFAP46	1631	Q8IYW2
LEDIDECQELPGLCQ	FBN3	1561	Q75N90
DEAAVPVLCICSADD	ABHD15	346	Q6UXT9
LDVLGPCLVCGTDAE	NUP43	356	Q8NFH3
AICLICGDRQDLEEP	RARB	331	P10826
PRDELVEAACALTCD	RFX5	196	P48382
RNEECDPGGCLLELT	ANO6	591	Q4KMQ2
GALVLSDNGICCIDE	MCM4	561	P33991
LEQCDVPEDVRVGCL	NOB1	221	Q9ULX3
ATDPGRLLLCDDCDI	KMT2C	1016	Q8NEZ4
CDAGCLPAEEVDVLL	ARHGAP45	261	Q92619
LDLGDEIDCDVPTCG	LRP12	246	Q9Y561
ELADLGLAEQAPCIC	LZTS2	646	Q9BRK4
GLAEQAPCICLEEIT	LZTS2	651	Q9BRK4
CDCNLEGVLPEICDA	LAMA3	491	Q16787
LPEDCAEALATAACL	IRAK2	466	O43187
YPCDVEDCEALGALV	FRMD8	161	Q9BZ67
ARPECLGALVDCLVF	LONRF1	81	Q17RB8
LENCIEEALEPGACC	FBLN2	41	P98095
GDALELLVSPECNCD	ITGB6	441	P18564
IDVDECLRPDVCGEG	LTBP1	956	Q14766
CPEVLEEGCEEATGV	FGD5	271	Q6ZNL6
NPEEICRCLGISLEE	GALK2	296	Q01415
LDCDCVLTGEDILGE	MACF1	416	O94854
AALLNDCVCDGLERP	GAS1	216	P54826
LGDIEDFDGRPCIVC	RFESD	66	Q8TAC1
EPEDIDLLECCLQEL	FAM170B	176	A6NMN3
ASEPDEALVDECCLL	MED16	706	Q9Y2X0
VDDEGLCPAGQLCLD	GRIN3A	531	Q8TCU5
DIECAALVGEDQPLC	PPARGC1A	16	Q9UBK2
GVDADVLLEACCADG	FBLN1	26	P23142
GVTCEDIDECALPTG	FBLN1	476	P23142
ILLDCGEDNICVPDL	ITGA5	641	P08648
DEVCGCPLVRDVFEL	CXXC1	561	Q9P0U4
EILVLVGGCDQDCDE	KLHL21	286	Q9UJP4
ICEGLREVCQPAFDA	CPZ	121	Q66K79
LSDRPVDCLDGACLA	C5AR2	16	Q9P296
VDCLDGACLAIDPLR	C5AR2	21	Q9P296
GLTVEGPCEAQLECL	FLNA	1101	P21333
PDGRTCVDINECLLE	FBN1	1966	P35555
CGALELEGVEVCVQL	DIS3L	646	Q8TF46
LPCACGQLPDLEDEL	CRAMP1	541	Q96RY5
DCDLPCDLDCGILDA	MDFI	211	Q99750
DRCLPVCIDVGTDNI	ME2	196	P23368
RAGPDLASCLDVDEC	LTBP4	951	Q8N2S1
TECEPGCAVDLGLAR	CAMKK2	56	Q96RR4
SEPVLLEGECLVVCE	CBLN3	36	Q6UW01
LEGECLVVCEPGRAA	CBLN3	41	Q6UW01
LCDDIICDDQELDCP	COL3A1	61	P02461
ACGVVDEAVLVCPDP	EMC1	226	Q8N766
CEDIDECSIIPGICE	FBN2	316	P35556
GRDINECALDPDICA	FBN2	766	P35556
ECALDPDICANGICE	FBN2	771	P35556
PDASGRNCIDIDECL	FBN2	801	P35556
AVDIDECKEIPGICA	FBN2	1806	P35556
DFDCCLVVPLIAESG	GRIP1	1061	Q9Y3R0
CCLAVPLLAEAGDVL	GRIP2	1001	Q9C0E4
DLLVCNCAVAALGDP	FASN	1311	P49327
DVDEDLICPICSGVL	RNF41	11	Q9H4P4
LEIVCLIDPGCFREI	SBDS	206	Q9Y3A5
ALCLQAELGECELPE	EPB41L4B	206	Q9H329
LVCVRTDGEGEDPEC	IRGQ	326	Q8WZA9
GLCGICNEDPDDDLR	OTOGL	1681	Q3ZCN5
DAILEACLCGETAIP	PTPRK	1136	Q15262
ACSEDCIVVEGPILD	IZUMO3	131	Q5VZ72
GPEAAECLVCSELAL	MIB2	826	Q96AX9
GALVLADAGLCCIDE	MCM9	401	Q9NXL9
GDICAICQAEFREPL	RNFT2	381	Q96EX2
LCVNGCPLSERIDDG	RGMB	311	Q6NW40
DEDLDELCPVCGDKV	NR5A1	6	Q13285
DLVDGECVEPVDPCF	THBD	356	P07204
ELACLANLCPETAEE	POLR2D	96	O15514
PCLELEPFDCGCDEI	PRUNE2	316	Q8WUY3
EELVPACAEGEALCQ	SSPOP	1371	A2VEC9
CPICRVDIETQLGAD	RNF165	331	Q6ZSG1
ELIVLGCCEEGGEET	PELI3	46	Q8N2H9
VDDSLEQPCGLGCLV	SLCO6A1	81	Q86UG4
ALFPDEVGCVDPDVC	SLC5A9	341	Q2M3M2
GDGLVDCLDPDCCLQ	TENM2	856	Q9NT68
CDEKGIECDVLLEPN	SANBR	511	Q6NSI8
LRCEGDVDECLDQPC	NOTCH4	1001	Q99466
EIPCFVLEEQEACVA	PLA2G3	241	Q9NZ20
CLVCLDAPGGVELSD	CHAT	386	P28329
CSDCEVEVLPLGLET	SETDB2	436	Q96T68
ECAGGLECACPALLE	VWF	256	P04275
CPEGQLLDEGLCVES	VWF	331	P04275
LEADCVRGPDGVCLS	PBXIP1	341	Q96AQ6
LEGEAATLLCLPAAC	SPEG	2596	Q15772
ECRILVGCGVDELPA	SH3RF3	96	Q8TEJ3
DEAAPVCIGSCLVDI	ARHGAP23	751	Q9P227
SCELSCLEGPEEELE	ROBO3	1091	Q96MS0
VCALSEADLIEFPCD	TRIL	771	Q7L0X0
LEECGLQEGDITALC	SMCO1	126	Q147U7
LLQEAGPSEACCVRD	TNK1	376	Q13470
GGEQDCALEELCKPL	ZMAT3	56	Q9HA38
LGCLEDIEEALCGPA	TNFRSF1A	431	P19438
AGECVICLEELLQGD	ZNRF1	181	Q8ND25
LLGDVLDCLPLDQCD	THOC1	96	Q96FV9
VEADELLQACGECRP	KLHL35	256	Q6PF15