Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

4.11e-075703GO:0030156
GeneOntologyMolecularFunctionsuperoxide-generating NADPH oxidase activator activity

NCF1 NCF1C NCF1B

4.86e-0610703GO:0016176
GeneOntologyMolecularFunctionsuperoxide-generating NAD(P)H oxidase activity

NCF1 NCF1C NCF1B

8.87e-0612703GO:0016175
GeneOntologyMolecularFunctionribonucleoside-diphosphate reductase activity

RRM2B RRM1

3.63e-053702GO:0061731
GeneOntologyMolecularFunctionribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor

RRM2B RRM1

3.63e-053702GO:0004748
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

NCF1 NCF1C NCF1B

4.51e-0520703GO:0050664
GeneOntologyMolecularFunctionenzyme activator activity

ARHGDIA TBC1D15 PSME4 NCF1 RICTOR RABGAP1 AGAP9 NCF1C NCF1B CTSK

9.17e-056567010GO:0008047
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor

RRM2B RRM1

1.20e-045702GO:0016728
GeneOntologyMolecularFunctionphosphatidylinositol-3,4-bisphosphate binding

NCF1 NCF1C NCF1B

2.49e-0435703GO:0043325
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H

NCF1 NDUFA5 NCF1C NCF1B

3.47e-0495704GO:0016651
GeneOntologyMolecularFunctionenzyme regulator activity

ARHGDIA TBC1D15 PSME4 NCF1 RICTOR RABGAP1 EPS8L3 AGAP9 LYN NCF1C NCF1B CTSK SERPINA9 NOS1AP

3.48e-0414187014GO:0030234
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

KMT2C SMYD3

5.35e-0410702GO:0140999
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH or CH2 groups

RRM2B RRM1

1.24e-0315702GO:0016725
GeneOntologyMolecularFunctionSH3 domain binding

NCF1 LYN NCF1C NCF1B

1.60e-03143704GO:0017124
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

KMT2C SMYD3

2.21e-0320702GO:0042800
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

BRIP1 ATAD5 CHTF18 PLD3 DNMT3A

2.26e-03262705GO:0140097
GeneOntologyBiologicalProcessneutrophil-mediated killing of gram-positive bacterium

NCF1 NCF1C NCF1B

3.89e-075713GO:0070946
GeneOntologyBiologicalProcessNADP catabolic process

NCF1 NCF1C NCF1B

1.35e-067713GO:0006742
GeneOntologyBiologicalProcessneutrophil-mediated killing of fungus

NCF1 NCF1C NCF1B

1.35e-067713GO:0070947
GeneOntologyBiologicalProcessregulation of respiratory burst involved in inflammatory response

NCF1 NCF1C NCF1B

6.32e-0611713GO:0060264
GeneOntologyBiologicalProcessrespiratory burst involved in inflammatory response

NCF1 NCF1C NCF1B

1.09e-0513713GO:0002536
GeneOntologyBiologicalProcessneutrophil-mediated killing of bacterium

NCF1 NCF1C NCF1B

2.12e-0516713GO:0070944
GeneOntologyBiologicalProcessresponse to yeast

NCF1 NCF1C NCF1B

3.07e-0518713GO:0001878
GeneOntologyBiologicalProcessneutrophil-mediated killing of symbiont cell

NCF1 NCF1C NCF1B

3.64e-0519713GO:0070943
GeneOntologyBiologicalProcessNADP metabolic process

NCF1 NCF1C NCF1B DERA

4.14e-0556714GO:0006739
GeneOntologyBiologicalProcessrespiratory burst involved in defense response

NCF1 NCF1C NCF1B

4.27e-0520713GO:0002679
GeneOntologyBiologicalProcessneutrophil mediated cytotoxicity

NCF1 NCF1C NCF1B

4.97e-0521713GO:0070942
GeneOntologyBiologicalProcessnegative regulation of smooth muscle contraction

NCF1 NCF1C NCF1B

5.74e-0522713GO:0045986
GeneOntologyBiologicalProcesshydrogen peroxide biosynthetic process

NCF1 NCF1C NCF1B

5.74e-0522713GO:0050665
GeneOntologyBiologicalProcessregulation of respiratory burst

NCF1 NCF1C NCF1B

6.59e-0523713GO:0060263
GeneOntologyBiologicalProcessproduction of molecular mediator involved in inflammatory response

NCF1 PLD3 LYN NCF1C NCF1B

9.57e-05133715GO:0002532
GeneOntologyBiologicalProcessmeiosis I

BRIP1 CHTF18 RAD21L1 PSMD13 RAD21

1.53e-04147715GO:0007127
GeneOntologyBiologicalProcessmeiosis I cell cycle process

BRIP1 CHTF18 RAD21L1 PSMD13 RAD21

1.96e-04155715GO:0061982
GeneOntologyBiologicalProcesspositive regulation of cell cycle G2/M phase transition

ATAD5 RRM2B RRM1

1.98e-0433713GO:1902751
GeneOntologyBiologicalProcessnegative regulation of muscle contraction

NCF1 NCF1C NCF1B

2.36e-0435713GO:0045932
GeneOntologyBiologicalProcessgerm cell development

RIMBP3 ADGB BRIP1 PSME4 CHTF18 RIMBP3C RIMBP3B DNMT3A

2.46e-04482718GO:0007281
GeneOntologyBiologicalProcessneuromuscular synaptic transmission

RIMBP3 RIMBP3C RIMBP3B

2.57e-0436713GO:0007274
GeneOntologyBiologicalProcessnucleobase-containing small molecule metabolic process

SULT1B1 RRM2B NCF1 ACSF3 NDUFA5 RRM1 NCF1C ADA2 NCF1B DERA

2.83e-047677110GO:0055086
GeneOntologyBiologicalProcessspermatid development

RIMBP3 ADGB BRIP1 PSME4 RIMBP3C RIMBP3B

2.85e-04262716GO:0007286
GeneOntologyBiologicalProcesskilling by host of symbiont cells

NCF1 NCF1C NCF1B

3.02e-0438713GO:0051873
GeneOntologyBiologicalProcesspositive regulation of G0 to G1 transition

RRM2B RRM1

3.23e-048712GO:0070318
GeneOntologyBiologicalProcessreplication-born double-strand break repair via sister chromatid exchange

RAD21L1 RAD21

3.23e-048712GO:1990414
GeneOntologyBiologicalProcessspermatid differentiation

RIMBP3 ADGB BRIP1 PSME4 RIMBP3C RIMBP3B

3.48e-04272716GO:0048515
GeneOntologyBiologicalProcessleukotriene metabolic process

NCF1 NCF1C NCF1B

3.79e-0441713GO:0006691
GeneOntologyBiologicalProcessregulation of G0 to G1 transition

RRM2B SMARCC1 RRM1

4.08e-0442713GO:0070316
GeneOntologyBiologicalProcessrespiratory burst

NCF1 NCF1C NCF1B

4.37e-0443713GO:0045730
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

RIMBP3 ADGB BRIP1 PSME4 CHTF18 RIMBP3C RIMBP3B DNMT3A

4.46e-04527718GO:0022412
GeneOntologyBiologicalProcessG0 to G1 transition

RRM2B SMARCC1 RRM1

4.68e-0444713GO:0045023
GeneOntologyBiologicalProcessnucleotide metabolic process

SULT1B1 RRM2B NCF1 ACSF3 NDUFA5 RRM1 NCF1C NCF1B DERA

5.46e-04684719GO:0009117
GeneOntologyBiologicalProcessnucleoside phosphate metabolic process

SULT1B1 RRM2B NCF1 ACSF3 NDUFA5 RRM1 NCF1C NCF1B DERA

5.88e-04691719GO:0006753
GeneOntologyBiologicalProcessneutrophil mediated immunity

NCF1 NCF1C NCF1B

6.05e-0448713GO:0002446
GeneOntologyBiologicalProcesssuperoxide anion generation

NCF1 NCF1C NCF1B

6.82e-0450713GO:0042554
GeneOntologyBiologicalProcessdeoxyribose phosphate metabolic process

RRM2B RRM1 DERA

9.51e-0456713GO:0019692
GeneOntologyBiologicalProcessdeoxyribonucleotide metabolic process

RRM2B RRM1 DERA

1.00e-0357713GO:0009262
GeneOntologyCellularComponentoxidoreductase complex

RRM2B NCF1 NDUFA5 RRM1 NCF1C NCF1B

1.80e-05161716GO:1990204
GeneOntologyCellularComponentNADPH oxidase complex

NCF1 NCF1C NCF1B

2.95e-0518713GO:0043020
GeneOntologyCellularComponentribonucleoside-diphosphate reductase complex

RRM2B RRM1

3.40e-053712GO:0005971
GeneOntologyCellularComponentapical cytoplasm

VANGL2 MYO7B

6.79e-054712GO:0090651
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3C RIMBP3B

1.16e-0428713GO:0002177
GeneOntologyCellularComponentmeiotic cohesin complex

RAD21L1 RAD21

2.36e-047712GO:0030893
GeneOntologyCellularComponentcytoplasmic side of plasma membrane

NCF1 FERMT2 LYN NCF1C NCF1B

4.17e-04185715GO:0009898
GeneOntologyCellularComponentcohesin complex

RAD21L1 RAD21

6.13e-0411712GO:0008278
GeneOntologyCellularComponentcytoplasmic side of membrane

NCF1 FERMT2 LYN NCF1C NCF1B

1.11e-03230715GO:0098562
HumanPhenoLupus anticoagulant

LYN ADA2 STAT4

3.61e-067253HP:0025343
MousePhenoabnormal angiotensin I-converting enzyme activity

NCF1 NCF1C NCF1B

1.21e-066563MP:0013254
MousePhenoincreased angiotensin I-converting enzyme activity

NCF1 NCF1C NCF1B

1.21e-066563MP:0003184
MousePhenoliver abscess

NCF1 NCF1C NCF1B

2.11e-067563MP:0003332
MousePhenoimpaired granulocyte bactericidal activity

NCF1 NCF1C NCF1B

7.16e-0610563MP:0005074
MousePhenodecreased susceptibility to Orthomyxoviridae infection

NCF1 NCF1C NCF1B

4.76e-0518563MP:0020947
MousePhenoectopic manchette

RIMBP3 RIMBP3C RIMBP3B

5.64e-0519563MP:0009377
MousePhenodetached sperm flagellum

RIMBP3 RIMBP3C RIMBP3B

7.70e-0521563MP:0008893
MousePhenodecreased vasoconstriction

NCF1 NCF1C NCF1B

8.88e-0522563MP:0003026
MousePhenoincreased circulating renin level

NCF1 NCF1C NCF1B

1.02e-0423563MP:0003352
MousePhenoabnormal circulating renin level

NCF1 NCF1C NCF1B

2.07e-0429563MP:0003349
MousePhenoincreased Harderian gland tumor incidence

BRIP1 ATAD5

2.34e-046562MP:0012437
MousePhenooxidative stress

NCF1 NCF1C NCF1B ALDH7A1 NOS1AP

3.48e-04152565MP:0003674
MousePhenoimpaired smooth muscle contractility

NCF1 NCF1C NCF1B

3.64e-0435563MP:0000740
MousePhenogranulomatous inflammation

NCF1 NCF1C NCF1B

3.96e-0436563MP:0002500
DomainSH3

RIMBP3 MYO7B NCF1 RIMBP3C EPS8L3 RIMBP3B LYN

1.62e-05216707SM00326
DomainSH3

RIMBP3 MYO7B NCF1 RIMBP3C EPS8L3 RIMBP3B LYN

1.62e-05216707PS50002
DomainSH3_domain

RIMBP3 MYO7B NCF1 RIMBP3C EPS8L3 RIMBP3B LYN

1.83e-05220707IPR001452
DomainRad21/Rec8_C_eu

RAD21L1 RAD21

4.14e-053702IPR006909
DomainRad21_Rec8_N

RAD21L1 RAD21

4.14e-053702IPR006910
Domain-

RAD21L1 RAD21

4.14e-0537021.10.10.580
DomainRad21_Rec8_N

RAD21L1 RAD21

4.14e-053702PF04825
DomainRad21_Rec8

RAD21L1 RAD21

4.14e-053702PF04824
DomainRad21/Rec8_C

RAD21L1 RAD21

4.14e-053702IPR023093
DomainSLC35_F1/F2/F6

SLC35F2 SLC35F1

8.27e-054702IPR009262
DomainSLC35F

SLC35F2 SLC35F1

8.27e-054702PF06027
DomainSH3_2

RIMBP3 MYO7B RIMBP3C RIMBP3B

3.05e-0486704IPR011511
DomainSH3_2

RIMBP3 MYO7B RIMBP3C RIMBP3B

3.05e-0486704PF07653
Domain-

SULT1B1 SAMD9L BRIP1 MYO7B ATAD5 CHTF18 AGAP9 NKIRAS2 DNAH5

1.81e-037467093.40.50.300
DomainSH3_9

RIMBP3 RIMBP3C RIMBP3B

3.14e-0378703PF14604
DomainP-loop_NTPase

SULT1B1 SAMD9L BRIP1 MYO7B ATAD5 CHTF18 AGAP9 NKIRAS2 DNAH5

4.27e-03848709IPR027417
DomainPID

RABGAP1 NOS1AP

4.91e-0328702PF00640
DomainPH_dom-like

MYO7B RABGAP1 EPS8L3 AGAP9 FERMT2 NOS1AP

5.21e-03426706IPR011993
DomainPID

RABGAP1 NOS1AP

6.39e-0332702PS01179
PathwayREACTOME_CROSS_PRESENTATION_OF_PARTICULATE_EXOGENOUS_ANTIGENS_PHAGOSOMES

NCF1 NCF1C NCF1B

4.15e-069533MM14524
PathwayREACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION

PSME4 NCF1 PSMD13 NCF1C NCF1B

9.35e-0676535MM14526
PathwayWP_MICROGLIA_PATHOGEN_PHAGOCYTOSIS_PATHWAY

NCF1 LYN NCF1C NCF1B

2.58e-0546534MM15837
PathwayREACTOME_RHO_GTPASES_ACTIVATE_NADPH_OXIDASES

NCF1 NCF1C NCF1B

1.09e-0425533MM15269
PathwayREACTOME_INNATE_IMMUNE_SYSTEM

PSME4 ARPC1A NCF1 PSMD13 PLD3 NKIRAS2 LYN NCF1C NCF1B CTSK CAP1 DERA

2.56e-049955312MM14661
PathwayBIOCARTA_FMLP_PATHWAY

NCF1 NCF1C NCF1B

2.77e-0434533MM1399
PathwayREACTOME_DETOXIFICATION_OF_REACTIVE_OXYGEN_SPECIES

NCF1 NCF1C NCF1B

3.02e-0435533MM14944
PathwayREACTOME_RAC2_GTPASE_CYCLE

ARHGDIA NCF1 NCF1C NCF1B

3.15e-0487534MM15600
PathwayREACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS

PSME4 NCF1 PSMD13 NCF1C NCF1B

3.46e-04162535MM15688
PathwayREACTOME_ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES

NCF1 NCF1C NCF1B

3.86e-0438533MM14519
PathwayREACTOME_RAC3_GTPASE_CYCLE

NCF1 FERMT2 NCF1C NCF1B

4.06e-0493534MM15609
PathwayREACTOME_RAC1_GTPASE_CYCLE

ARHGDIA NCF1 FERMT2 NCF1C NCF1B

4.93e-04175535MM15599
PathwayREACTOME_SIGNALING_BY_VEGF

NCF1 RICTOR NCF1C NCF1B

5.98e-04103534MM14752
Pubmed

Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia.

NCF1 NCF1C NCF1B

8.87e-09373318036262
Pubmed

Transient loss of resistance to pulmonary tuberculosis in p47(phox-/-) mice.

NCF1 NCF1C NCF1B

8.87e-09373310678931
Pubmed

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.

NCF1 NCF1C NCF1B

8.87e-09373327044504
Pubmed

Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.

NCF1 NCF1C NCF1B

8.87e-09373317167081
Pubmed

Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.

NCF1 NCF1C NCF1B

8.87e-09373324358335
Pubmed

Molecular characterization of the mouse p47-phox (Ncf1) gene and comparative analysis of the mouse p47-phox (Ncf1) gene to the human NCF1 gene.

NCF1 NCF1C NCF1B

8.87e-09373310891396
Pubmed

P47phox-/- mice are compromised in expansion and activation of CD8+ T cells and susceptible to Trypanosoma cruzi infection.

NCF1 NCF1C NCF1B

8.87e-09373325474113
Pubmed

NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.

NCF1 NCF1C NCF1B

8.87e-09373318787174
Pubmed

NAD(P)H oxidase subunit p47phox is elevated, and p47phox knockout prevents diaphragm contractile dysfunction in heart failure.

NCF1 NCF1C NCF1B

8.87e-09373326209274
Pubmed

Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.

NCF1 NCF1C NCF1B

8.87e-09373324873968
Pubmed

p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.

NCF1 NCF1C NCF1B

8.87e-09373322184329
Pubmed

NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.

NCF1 NCF1C NCF1B

8.87e-09373311018074
Pubmed

Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis.

NCF1 NCF1C NCF1B

8.87e-09373333545139
Pubmed

Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.

NCF1 NCF1C NCF1B

8.87e-09373320142487
Pubmed

Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

8.87e-0937339116268
Pubmed

Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.

NCF1 NCF1C NCF1B

8.87e-09373320686129
Pubmed

Angiotensin II induced catabolic effect and muscle atrophy are redox dependent.

NCF1 NCF1C NCF1B

8.87e-09373321570954
Pubmed

p47(phox) contributes to albuminuria and kidney fibrosis in mice.

NCF1 NCF1C NCF1B

8.87e-09373325565313
Pubmed

Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.

NCF1 NCF1C NCF1B

8.87e-09373339357591
Pubmed

Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion.

NCF1 NCF1C NCF1B

8.87e-09373312958309
Pubmed

Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells.

NCF1 NCF1C NCF1B

8.87e-09373311435342
Pubmed

Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8+ T Cell Activation via Cross-Presentation in Type 1 Diabetes.

NCF1 NCF1C NCF1B

8.87e-09373331118934
Pubmed

Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity.

NCF1 NCF1C NCF1B

8.87e-09373323482812
Pubmed

Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice.

NCF1 NCF1C NCF1B

8.87e-09373316041040
Pubmed

The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs.

NCF1 NCF1C NCF1B

8.87e-09373310085000
Pubmed

Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.

NCF1 NCF1C NCF1B

8.87e-09373310987289
Pubmed

Methamphetamine alters occludin expression via NADPH oxidase-induced oxidative insult and intact caveolae.

NCF1 NCF1C NCF1B

8.87e-09373321435178
Pubmed

Intermittent hypoxia has organ-specific effects on oxidative stress.

NCF1 NCF1C NCF1B

8.87e-09373318703411
Pubmed

Mycobacterial infection induces higher interleukin-1β and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase.

NCF1 NCF1C NCF1B

8.87e-09373329228045
Pubmed

Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion.

NCF1 NCF1C NCF1B

8.87e-09373317307863
Pubmed

Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate.

NCF1 NCF1C NCF1B

8.87e-09373322155727
Pubmed

Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.

NCF1 NCF1C NCF1B

8.87e-09373327829407
Pubmed

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction.

NCF1 NCF1C NCF1B

8.87e-09373324576409
Pubmed

The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.

NCF1 NCF1C NCF1B

8.87e-09373322376231
Pubmed

Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.

NCF1 NCF1C NCF1B

8.87e-09373323918780
Pubmed

NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells.

NCF1 NCF1C NCF1B

8.87e-09373328274989
Pubmed

The p47phox deficiency significantly attenuates the pathogenicity of Chlamydia muridarum in the mouse oviduct but not uterine tissues.

NCF1 NCF1C NCF1B

8.87e-09373326645958
Pubmed

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.

NCF1 NCF1C NCF1B

8.87e-09373312364355
Pubmed

NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.

NCF1 NCF1C NCF1B

8.87e-09373324549323
Pubmed

NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities.

NCF1 NCF1C NCF1B

8.87e-09373334557202
Pubmed

Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.

NCF1 NCF1C NCF1B

8.87e-09373328467721
Pubmed

P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+.

NCF1 NCF1C NCF1B

8.87e-09373310670582
Pubmed

NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity.

NCF1 NCF1C NCF1B

8.87e-09373320881184
Pubmed

Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.

NCF1 NCF1C NCF1B

8.87e-09373326528554
Pubmed

The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis.

NCF1 NCF1C NCF1B

8.87e-09373319052348
Pubmed

Effect of early particulate air pollution exposure on obesity in mice: role of p47phox.

NCF1 NCF1C NCF1B

8.87e-09373320864666
Pubmed

Reactive oxygen species delay control of lymphocytic choriomeningitis virus.

NCF1 NCF1C NCF1B

8.87e-09373323328631
Pubmed

p47phox-Dependent Oxidant Signalling through ASK1, MKK3/6 and MAPKs in Angiotensin II-Induced Cardiac Hypertrophy and Apoptosis.

NCF1 NCF1C NCF1B

8.87e-09373334572995
Pubmed

Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.

NCF1 NCF1C NCF1B

8.87e-09373317114280
Pubmed

Participation of mitochondrial respiratory complex III in neutrophil activation and lung injury.

NCF1 NCF1C NCF1B

8.87e-09373319168575
Pubmed

B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.

NCF1 NCF1C NCF1B

8.87e-09373325989352
Pubmed

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation.

NCF1 NCF1C NCF1B

8.87e-09373319503084
Pubmed

Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase.

NCF1 NCF1C NCF1B

8.87e-09373317404617
Pubmed

Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction.

NCF1 NCF1C NCF1B

8.87e-09373317332431
Pubmed

Lpp of Escherichia coli K1 inhibits host ROS production to counteract neutrophil-mediated elimination.

NCF1 NCF1C NCF1B

8.87e-09373336592568
Pubmed

Genetic requirement of p47phox for superoxide production by murine microglia.

NCF1 NCF1C NCF1B

8.87e-09373311156938
Pubmed

Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression.

NCF1 NCF1C NCF1B

8.87e-09373330504842
Pubmed

Genomic structure of the human p47-phox (NCF1) gene.

NCF1 NCF1C NCF1B

8.87e-09373310772875
Pubmed

A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca2+ Release During Axonal Specification.

NCF1 NCF1C NCF1B

8.87e-09373327798190
Pubmed

Endothelium-dependent coronary vasodilatation requires NADPH oxidase-derived reactive oxygen species.

NCF1 NCF1C NCF1B

8.87e-09373320702812
Pubmed

Direct interaction of HIV gp120 with neuronal CXCR4 and CCR5 receptors induces cofilin-actin rod pathology via a cellular prion protein- and NOX-dependent mechanism.

NCF1 NCF1C NCF1B

8.87e-09373333705493
Pubmed

Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis.

NCF1 NCF1C NCF1B

8.87e-09373323965970
Pubmed

Macrophage-derived reactive oxygen species protects against autoimmune priming with a defined polymeric adjuvant.

NCF1 NCF1C NCF1B

8.87e-09373326455429
Pubmed

Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice.

NCF1 NCF1C NCF1B

8.87e-09373315513930
Pubmed

Conditional haploinsufficiency of NCF1 (encoding p47(phox)), a signaling gene with a heterozygous phenotype potentially subject to natural selection.

NCF1 NCF1C NCF1B

8.87e-09373315626477
Pubmed

Phosphoinositide 3-kinase regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling cPKC/PKCdelta but not Akt.

NCF1 NCF1C NCF1B

8.87e-09373315033459
Pubmed

NCF1 gene and pseudogene pattern: association with parasitic infection and autoimmunity.

NCF1 NCF1C NCF1B

8.87e-09373319077231
Pubmed

Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles.

NCF1 NCF1C NCF1B

8.87e-09373320828610
Pubmed

p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation.

NCF1 NCF1C NCF1B

8.87e-09373320817944
Pubmed

Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.

NCF1 NCF1C NCF1B

8.87e-09373322319452
Pubmed

Early determinants of H2O2-induced endothelial dysfunction.

NCF1 NCF1C NCF1B

8.87e-09373316895801
Pubmed

Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis.

NCF1 NCF1C NCF1B

8.87e-09373320690191
Pubmed

Endosomal acidification and activation of NADPH oxidase isoforms are upstream events in hyperosmolarity-induced hepatocyte apoptosis.

NCF1 NCF1C NCF1B

8.87e-09373316772302
Pubmed

Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice.

NCF1 NCF1C NCF1B

8.87e-09373332504071
Pubmed

Effect of p47phox gene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells.

NCF1 NCF1C NCF1B

8.87e-09373316280459
Pubmed

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.

NCF1 NCF1C NCF1B

8.87e-09373318185592
Pubmed

NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions.

NCF1 NCF1C NCF1B

8.87e-09373336853827
Pubmed

Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation.

NCF1 NCF1C NCF1B

8.87e-09373323024271
Pubmed

Ncf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells.

NCF1 NCF1C NCF1B

8.87e-09373321253614
Pubmed

Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2.

NCF1 NCF1C NCF1B

8.87e-09373325873172
Pubmed

Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene.

NCF1 NCF1C NCF1B

8.87e-09373315310853
Pubmed

Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21.

NCF1 NCF1C NCF1B

8.87e-09373331393787
Pubmed

Vascular effects following homozygous disruption of p47(phox) : An essential component of NADPH oxidase.

NCF1 NCF1C NCF1B

8.87e-09373310725280
Pubmed

Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice.

NCF1 NCF1C NCF1B

8.87e-09373334970267
Pubmed

Germ-free mice deficient of reactive oxygen species have increased arthritis susceptibility.

NCF1 NCF1C NCF1B

8.87e-09373325689796
Pubmed

Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation.

NCF1 NCF1C NCF1B

8.87e-09373314993144
Pubmed

Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation.

NCF1 NCF1C NCF1B

8.87e-09373322050439
Pubmed

The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.

NCF1 NCF1C NCF1B

8.87e-09373312031896
Pubmed

NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion.

NCF1 NCF1C NCF1B

8.87e-09373311249873
Pubmed

Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice.

NCF1 NCF1C NCF1B

8.87e-09373315936744
Pubmed

NADPH oxidase modulates myocardial Akt, ERK1/2 activation, and angiogenesis after hypoxia-reoxygenation.

NCF1 NCF1C NCF1B

8.87e-09373317220182
Pubmed

NADPH oxidase p47phox siRNA attenuates adventitial fibroblasts proliferation and migration in apoE(-/-) mouse.

NCF1 NCF1C NCF1B

8.87e-09373325628043
Pubmed

The p47phox mouse knock-out model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

8.87e-0937337650482
Pubmed

Disseminated trichosporonosis in a murine model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

8.87e-09373312868577
Pubmed

Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. Role of the p47phox subunit.

NCF1 NCF1C NCF1B

8.87e-09373312560337
Pubmed

NADPH oxidase mediates striatal neuronal injury after transient global cerebral ischemia.

NCF1 NCF1C NCF1B

8.87e-09373320859296
Pubmed

Inhibition of endothelial Nox2 activation by LMH001 protects mice from angiotensin II-induced vascular oxidative stress, hypertension and aortic aneurysm.

NCF1 NCF1C NCF1B

8.87e-09373335276443
Pubmed

p47phox-dependent NADPH oxidase regulates flow-induced vascular remodeling.

NCF1 NCF1C NCF1B

8.87e-09373316109921
Pubmed

Reactive oxygen species modulate growth of cerebral aneurysms: a study using the free radical scavenger edaravone and p47phox(-/-) mice.

NCF1 NCF1C NCF1B

8.87e-09373319381132
Pubmed

Genetics of autoimmune diseases: a multistep process.

NCF1 NCF1C NCF1B

8.87e-09373316724810
Cytoband7q11.23

NCF1 NCF1C NCF1B

5.11e-04977337q11.23
Cytoband22q11.21

RIMBP3 RIMBP3C RIMBP3B

7.56e-0411173322q11.21
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2C SMYD3

2.82e-0334422487
GeneFamilyProteasome

PSME4 PSMD13

4.48e-0343422690
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

MYO7B FERMT2

6.01e-03504221293
GeneFamilyAAA ATPases

ATAD5 CHTF18

6.73e-0353422413
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO7B NCF1 LYN NCF1C NCF1B EIF2AK3

7.96e-07194736ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO7B NCF1 LYN NCF1C NCF1B EIF2AK3

8.71e-07197736fa3cc33c975648172feabb485c3bdd087f1f8ea7
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BRIP1 PLD3 RRM1 CTSK SMYD3

1.05e-05176735450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7B MROH2A GRIK3 SLC35F1 DNAH5

1.30e-051847352cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7B MROH2A GRIK3 SLC35F1 DNAH5

1.30e-05184735ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7B MROH2A GRIK3 SLC35F1 DNAH5

1.30e-051847352b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Skin-nan-21m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAUS4 BRIP1 CHTF18 RRM1 RAD21

1.59e-0519273596f23d6e8604d1cb24910d3118d8171b57c93e14
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TBC1D15 BRIP1 ATAD5 CHTF18 RRM1

1.68e-051947358f4b63b0b9a40765205e4ca6bd94a675a83dbe3d
ToppCellfacs-Thymus-nan-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRIP1 ATAD5 CHTF18 RRM1 RAD21

1.72e-0519573593c345e70d6c8ff5d12fd63d73228c1700b804a0
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_4|COVID-19_Mild / Disease condition and Cell class

VMP1 ARHGDIA NCF1 RICTOR ADA2

1.76e-051967353729d1444c65cad640377894decc64129bc3fd5b
ToppCelldistal-Hematologic-Interstitial_Macrophage-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCF1 NCF1C ADA2 NCF1B CTSK

1.76e-05196735e4f40274df940e0996c555082f2bb4f99e5b0881
ToppCellbackground-Kupffer_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

NCF1 HPX PLD3 LYN ADA2

1.89e-0519973591d229f3515d49639bcb5505e6aec4a9abade81c
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT1-AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EML5 EBPL MROH2A NOS1AP

3.47e-05112734456278fb92dd41820fde8cf27c68fec45e15f972
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma-2|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

BRIP1 RABGAP1 FERMT2 NOS1AP

6.59e-05132734a8e7e7f38af095d63e221bcc06a1e5147bb6e467
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Cpa6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STIM2 SAMD9L GRIK3 NOS1AP

1.20e-0415473412cbc38bc1f7231c67e1d2d5e86e95bc12e24682
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

KMT2C PSME4 RICTOR STAT4

1.26e-041567341545169694f686d28648a68b552c2ae606599d66
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A TRPM8 LRRC2 SERPINA9

1.39e-0416073441d6c811c445c0ba9b6a2deb10a3b6b793172582
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A TRPM8 LRRC2 SERPINA9

1.39e-04160734c1d03c0ac9c12615a06499209fcdf18e9b6f1fba
ToppCell5'-Adult-LymphNode-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BRIP1 NCF1 LYN SERPINA9

1.42e-04161734d8140e7772b4e327dafa3536881a784d3c328d2a
ToppCell5'-Adult-Appendix-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLCA1 RRM1 DNAH5 DCBLD2

1.52e-0416473429da0175bd3808a5b3039a6161c764105608ef96
ToppCell5'-Adult-Appendix-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLCA1 RRM1 DNAH5 DCBLD2

1.52e-04164734e83b632ac7e1dace946991ddfe1fbfbbffc3a88b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SULT1B1 NCF1 PRORY LYN

1.52e-041647342c929996a19bbe29949010928001c277b5494a42
ToppCellTCGA-Colorectal|World / Sample_Type by Project: Shred V9

SULT1B1 CLCA1 MYO7B EPS8L3

1.60e-04166734c018cd8c7a82251c67e3dc812d4d21e527a43456
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 ATAD5 CHTF18 RRM1

1.63e-04167734108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCellfacs-Heart-RV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSK DCBLD2 SERPINA9 ALDH7A1

1.75e-04170734d7c9a604311974ff87ece43a0f8725a234d262f7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Neutrophil|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SULT1B1 NCF1 PRORY LYN

1.79e-04171734ef9397cec7f5c217d34583f26270af7ed7fbcebf
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCF1 EPS8L3 PLD3 CTSK

1.83e-04172734584af6537685cb459bf0fc298e6f46872016c116
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSK DCBLD2 SERPINA9 ALDH7A1

2.00e-04176734c0a084f7a8645262d61971f094689e02bf15b113
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSK DCBLD2 SERPINA9 ALDH7A1

2.00e-04176734cccf9201f6e2da7524b911a5961d3b227edab222
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATAD5 SLC35F2 RRM1 SMYD3

2.00e-041767341510cdfcfb46ce1196a1220c07fb5f3986c81b78
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PSMD13 PLD3 RRM1 CTSK

2.00e-04176734270d7908dbd84028958d257f94941dc685e20255
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHTF18 SLC35F2 RRM1 CTSK

2.04e-041777341d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCellfacs-Heart-RA-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SULT1B1 STIM2 SMARCC1 EPS8L3

2.08e-04178734b505e2550860e777535ee95f29c936242fd607f1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 ATAD5 CHTF18 RRM1

2.13e-0417973488d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell15-Distal-Epithelial-Epithelial|Distal / Age, Tissue, Lineage and Cell class

LRRC2 GRIK3 SLC35F1 MIR9-1HG

2.17e-0418073499e2db9ad8e09fedc3542233553acece69f579f1
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 PLD3 RRM1 CTSK

2.32e-0418373442dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BRIP1 ATAD5 RRM1 SMYD3

2.32e-041837346c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAUS4 ATAD5 CHTF18 CTSK

2.36e-04184734b998803180322a5ea2b567928dea531c26816c3c
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

KMT2C RICTOR EIF2AK3 STAT4

2.57e-04188734ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIMBP3 GRIK3 SLC35F1 DNAH5

2.57e-04188734a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIMBP3 GRIK3 SLC35F1 DNAH5

2.57e-04188734c8530c9ff98666c64a94683261af4288cb790a7e
ToppCellcellseq-Immune-Hematopoietic-Granulocytic-Neutrophil|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SULT1B1 NCF1 LYN CAP1

2.62e-04189734fedab592be1d6520325b8c1b659b0a4dc3f4fe4d
ToppCell(2)_NK/T-(210)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

SAMD9L SMARCC1 LYN STAT4

2.62e-04189734fa72e87e1e8cd7cbddae7b47e19cf90d181820a7
ToppCell(2)_NK/T-(21)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

SAMD9L SMARCC1 LYN STAT4

2.62e-04189734b37ad24898a14a4a3b2d6cea2637de2471f76e20
ToppCell10x5'-GI_large-bowel-Lymphocytic_B-GC_B_(II)|GI_large-bowel / Manually curated celltypes from each tissue

BRIP1 NCF1 LYN SERPINA9

2.67e-04190734fee64bacbb330d04dc1dc63909838f2c605d9f1f
ToppCell10x5'-bone_marrow-Lymphocytic_B-Naive_B_cells|bone_marrow / Manually curated celltypes from each tissue

MYO7B NCF1 LYN EIF2AK3

2.78e-04192734fa99243ff028498c6a67d207a93e02c48e69cd42
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRIP1 ATAD5 CHTF18 RRM1

2.78e-04192734e8d47504b744040a762ec9b670a66cc060b2ae86
ToppCell21-Trachea-Epithelial-Epithelial|Trachea / Age, Tissue, Lineage and Cell class

EPS8L3 SLC35F1 CTSK MIR9-1HG

2.83e-041937349a8bb44a37f3202e3123a6680bd5545dc91a6d40
ToppCellfacs-Marrow-KLS-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAT4B GEMIN4 SMARCC1 RRM1

2.89e-04194734c9ebdcc2ea600975dade68a41fa65d1f8a5a5926
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B-Naive_B_cells|lymph-node_spleen / Manually curated celltypes from each tissue

MYO7B NCF1 LYN EIF2AK3

2.89e-0419473420967afbadb3cf80ba9f4d7ebda4e64389252e70
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BRIP1 ATAD5 CHTF18 RRM1

2.95e-04195734cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BRIP1 CHTF18 RRM1 CTSK

2.95e-04195734c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCell10x5'-bone_marrow-Lymphocytic_B|bone_marrow / Manually curated celltypes from each tissue

MYO7B NCF1 LYN EIF2AK3

2.95e-04195734bcbf0305ca9337a6f3021178dbb47a7fbf1030a4
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BRIP1 ATAD5 CHTF18 RRM1

3.01e-04196734df366d76ea55f49e349d622effa57c1535df8400
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VANGL2 VMP1 FERMT2 MIR9-1HG

3.01e-0419673445d1c0a962c4221c17393ee5566961d1deebf442
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

VMP1 ARHGDIA RICTOR ADA2

3.06e-04197734e666f6580e9a20b5e550f02125706db17eec8510
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NCF1 LYN ADA2 STAT4

3.06e-041977340523aec9713ae21e6b879aa98e07fa2576610d5f
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAUS4 ATAD5 CHTF18 RRM1

3.06e-04197734d9978aaa476b57144b0561f535ff1dd886c7512b
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BRIP1 MYO7B ATAD5 CHTF18

3.06e-04197734d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCellBL|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SULT1B1 SAMD9L NCF1 CAP1

3.06e-041977341acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCF1 LYN ADA2 STAT4

3.06e-0419773461ef3f417767c3f5296a26399da63e3e4f58faf8
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / Treatment groups by lineage, cell group, cell type

BRIP1 ATAD5 TMEM245 RRM1

3.06e-04197734038fd92750257d43d5e980fd06d77742b543f11a
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VMP1 NCF1 LYN ADA2

3.12e-04198734d347462ba6cb1c5a59c86dffbbe914cbc1e9cf16
ToppCellMultiple_Sclerosis-Myeloid|Multiple_Sclerosis / Disease, Lineage and Cell Type

VMP1 NCF1 LYN ADA2

3.12e-041987343c2817d95011ae372d0316ccf774e975536207b0
ToppCellsevere_COVID-19-T/NK_proliferative|severe_COVID-19 / disease group, cell group and cell class (v2)

BRIP1 ATAD5 CHTF18 RRM1

3.12e-04198734ed86b0247006befe55400c287d334d2202b470bd
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

VMP1 NCF1 LYN ADA2

3.12e-04198734c5a22846bccff948f90bc1d5fe309907dcd08348
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

KMT2C SAMD9L LYN ADA2

3.12e-0419873461ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellCOVID-19_Mild-Myeloid-Classical_Monocyte|COVID-19_Mild / Disease group, lineage and cell class

VMP1 NCF1 LYN ADA2

3.12e-04198734e78d027a095473af555762a4d542a73f5bb2e166
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VMP1 NCF1 LYN ADA2

3.12e-0419873406201b34d3e38f22c93b759511f7b376504bac06
ToppCellCOVID-19_Convalescent-Classical_Monocyte-cMono_2|COVID-19_Convalescent / Disease condition and Cell class

VMP1 NCF1 ADA2 CAP1

3.12e-04198734f65fd9b773aeafa55e38309479954a8e41371f52
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

VMP1 NCF1 LYN ADA2

3.12e-04198734c49c71b34151d82b8795763bcb633c301c35f659
ToppCelldistal-Hematologic-Interstitial_Macrophage|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCF1 NCF1C ADA2 CTSK

3.12e-04198734a35b43d38e18c6f8f0cd9015b8e23f71c729f023
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VMP1 NCF1 LYN ADA2

3.12e-041987344780f0276546962a2fc9f1041cfe49d2919d72b2
ToppCellMultiple_Sclerosis-Myeloid-CD14_Mono|Multiple_Sclerosis / Disease, Lineage and Cell Type

VMP1 NCF1 LYN ADA2

3.12e-04198734128969698b2b0468cf5374f695e2d9fd02227d13
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

VMP1 NCF1 LYN ADA2

3.12e-041987341ca91559fef231896e16180f5e050155c38f7cfa
ToppCelldistal-3-Hematologic-Interstitial_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCF1 NCF1C ADA2 CTSK

3.12e-04198734137a786da9f54b4f17e385a675d50a37de88f1b5
ToppCellIIF-Myeloid-CD14_Mono|IIF / Disease, Lineage and Cell Type

VMP1 NCF1 LYN ADA2

3.18e-04199734accfb3d8ad3f03f9302f2056ca16c1be6231a351
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRIK3 SLC35F1 RRM1 MIR9-1HG

3.18e-04199734ce699726ac4825c65bf934cb9a76202ad7340596
ToppCellBiopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

BRIP1 ATAD5 CHTF18 RRM1

3.18e-041997344fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCellhealthy_donor-Myeloid-Monocytic|healthy_donor / Disease condition, Lineage, Cell class and subclass

VMP1 NCF1 LYN ADA2

3.18e-04199734bd66a8d1a7cc92313328acc7c7ae0442faff951e
ToppCell10x5'-Lung-Myeloid_Mac-Cycling_Myeloid-Mac|Lung / Manually curated celltypes from each tissue

BRIP1 ATAD5 RRM1 ALDH7A1

3.18e-04199734dee1cf8ee850a2bd57349418a9bcc0948fe9ac9e
ToppCellMild-Myeloid-Macrophages-FCN1+SPP1+|Mild / Condition, Lineage, Cell class and cell subclass

NCF1 PLD3 LYN ADA2

3.18e-041997342cbaef86af870a228cb46895dd765ea8894c83c5
ToppCellCOVID-19_Convalescent-Classical_Monocyte-cMono_2|Classical_Monocyte / Disease condition and Cell class

NCF1 LYN ADA2 CAP1

3.18e-041997343feee9f53860b4b2e93ff2360beb2b2b74f51d24
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SAMD9L MYO7B NCF1 LYN

3.18e-04199734841338719d042247966867ac608146395eb8c4d9
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

BRIP1 ATAD5 CHTF18 RAD21

3.18e-0419973498575fcce726589e93fbb4df1aab03e57cb56076
ToppCellTransverse-Dendritic_cell-cycling_DCs|Dendritic_cell / Region, Cell class and subclass

ATAD5 PLD3 RRM1 RAD21

3.24e-04200734617a6a42f7b31eb3c45bdceaf55a591b6de7f154
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-T/NK_proliferative|Int-URO / Disease, condition lineage and cell class

BRIP1 ATAD5 CHTF18 RRM1

3.24e-0420073499acc1ea01288efdd5b166aa20d66735f2bbe543
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

EBPL TMEM245 FERMT2 DNMT3A

3.24e-04200734f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCell10x_3'_v2v3-Neoplastic|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARPC1A NDUFA5 FERMT2 MIR9-1HG

3.24e-04200734e9c7d7cb5fa63fc92aa91d02ae8bd05438d465bc
ToppCell356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

BRIP1 ATAD5 CHTF18 RRM1

3.24e-042007342afbb5b5742b956993796621fea7e0c9888754a1
ToppCell356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

BRIP1 ATAD5 CHTF18 RRM1

3.24e-042007344462ebd5d4632788f10a93fadd2babae701c754f
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BRIP1 ATAD5 CHTF18 RRM1

3.24e-04200734af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCellCOVID-19-COVID-19_Severe-Myeloid-Neutrophil|COVID-19_Severe / Disease, condition lineage and cell class

VMP1 SULT1B1 NCF1 LYN

3.24e-04200734fec2660c9a9977b3b3a2eaed063b9049c0b07ff2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCF1 LYN NCF1C NCF1B

3.24e-04200734851c57187db8bc91a393655bca5f13e787a723d4
Drug3-acetylisoquinoline

RRM2B GRIK3 RRM1

5.53e-076703CID000124656
DrugAC1L2O7O

RRM2B RRM1

9.32e-062702CID000075180
Drugtris(tetrabutylammonium) hydrogen pyrophosphate

RRM2B RRM1

9.32e-062702CID011115639
Drug2-amino-1-hydroxyguanidine

RRM2B RRM1

9.32e-062702CID005464082
DrugSureCN843110

RRM2B RRM1

9.32e-062702CID014570995
Drugv 1394

RRM2B RRM1

9.32e-062702CID000101484
DrugAdenosine phosphonoacetic acid

RRM2B RRM1

2.79e-053702CID000448505
DrugAC1N8OVF

RRM2B RRM1

2.79e-053702CID004347182
Drug2'-deoxytoyocamycin

RRM2B RRM1

2.79e-053702CID000204132
Drug2'-chloro-2'-dudp

RRM2B RRM1

2.79e-053702CID003082518
Drug1-amino-3-hydroxyguanidine

RRM2B RRM1

2.79e-053702CID009571038
DrugBild 1351

RRM2B RRM1

2.79e-053702CID005478827
Drugbeta-dimethylaminopropiophenone

RRM2B RRM1

2.79e-053702CID000077042
Drug3,4-dihydroxybenzaldoxime

RRM2B RRM1

2.79e-053702CID005388593
Drughydroxyguanidine sulfate

RRM2B RRM1

2.79e-053702CID000080667
Drug2D ABR

RRM2B RRM1

2.79e-053702CID000125209
DrugNSC-137029

RRM2B RRM1

2.79e-053702CID000421633
DrugBild 1357

RRM2B RRM1

2.79e-053702CID000515298
Drug2'-azido-2'-deoxycytidine 5'-diphosphate

RRM2B RRM1

2.79e-053702CID000170963
DrugAC1LAKEY

RRM2B RRM1

2.79e-053702CID000515340
DrugVal-Val-Asn-Asp-Leu

RRM2B RRM1

2.79e-053702CID000515343
Drug6-aminothymine

RRM2B RRM1

2.79e-053702CID000065245
Drugdial-CDP

RRM2B RRM1

2.79e-053702CID005487791
Drugcyclo(Sar-Sar

RRM2B RRM1

2.79e-053702CID000078761
DrugTenoxicam [59804-37-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A

ADGB HPX FERMT2 DCBLD2 ALDH7A1 MIR9-1HG

3.13e-051967064182_DN
Drug2-formylpyridine thiosemicarbazonato copper(II

RRM2B RRM1

5.57e-054702CID009576822
Drug4-nitro-benzohydrazide

RRM2B RRM1

5.57e-054702CID003693744
DrugAC1O7EGN

RRM2B RRM1

5.57e-054702CID006446439
DrugBPYTA

RRM2B RRM1

5.57e-054702CID003034633
Drug2-formylpyridine thiosemicarbazone

RRM2B RRM1

5.57e-054702CID001638752
Drugp-propoxyphenol

RRM2B RRM1

5.57e-054702CID000029352
DrugDacisteine

RRM2B RRM1

5.57e-054702CID000065690
Drug2'-azido-2'-deoxyuridine

RRM2B RRM1

5.57e-054702CID000168629
Drugmotropin

RRM2B RRM1

9.26e-055702CID000064657
DrugAC1NQVLK

RRM2B RRM1

9.26e-055702CID002732427
DrugA1110U

RRM2B RRM1

9.26e-055702CID003006964
Drug2-methylene-3-furanone

RRM2B RRM1

9.26e-055702CID000124504
Drug348U87

RRM2B RRM1

9.26e-055702CID003006985
Drug2-hydroxy-1-naphthylaldehyde benzoyl hydrazone

RRM2B RRM1

9.26e-055702CID005384003
Drugp-butoxyphenol

RRM2B RRM1

9.26e-055702CID000031233
DrugmdGuo

RRM2B RRM1

9.26e-055702CID000126596
Drugbruceine

RRM2B RRM1

9.26e-055702CID000122785
Drugacetylpyrazine

RRM2B RRM1

9.26e-055702CID000030914
DrugMdAdo

RRM2B RRM1

9.26e-055702CID000175972
DrugN-hydroxy-N'-methylurea

RRM2B RRM1

9.26e-055702CID000096412
DrugCitrusinine-I

RRM2B RRM1

9.26e-055702CID005487772
Drug2-acetylpyridine

RRM2B RRM1 DNAH5

9.60e-0529703CID000014286
Drugaucubin

RRM2B HPX RRM1

9.60e-0529703CID000091458
DrugVF 122

RRM2B RRM1

1.39e-046702CID000100590
DrugMK-410

RRM2B RRM1

1.39e-046702CID006451644
DrugTdho

RRM2B RRM1

1.39e-046702CID003037009
Drug2'-chloro-2'-deoxyadenosine

RRM2B RRM1

1.39e-046702CID000100327
DrugEHNA

RRM2B RRM1 ADA2 ALDH7A1

1.50e-0487704CID000003206
DrugS)-HPMPA

RRM2B HPX RRM1

1.85e-0436703CID000072253
Drugmonomethyl azelate

RRM2B RRM1

1.94e-047702CID000075009
DrugThiram

VANGL2 CHTF18 RRM2B SMARCC1 SLC35F2 PSMD13 RRM1 LYN

2.26e-04533708ctd:D013893
DrugGC Q

RRM2B RRM1

2.58e-048702CID006420157
Drugparabactin

RRM2B RRM1

2.58e-048702CID005487017
DrugB Hm

RRM2B RRM1

2.58e-048702CID000100038
Drughydroxamate 11

RRM2B RRM1

2.58e-048702CID010001582
DrugAC1MHU3O

RRM2B RRM1

2.58e-048702CID003032423
DrugN3UDP

RRM2B RRM1

2.58e-048702CID000169817
Drugbiochanin A

ARHGDIA NDUFA5 ALDH7A1 DERA

2.67e-04101704CID005280373
DrugAstemizole [68844-77-9]; Down 200; 8.8uM; HL60; HG-U133A

ATAD5 GEMIN4 SMARCC1 PSMD13 MIR9-1HG

3.14e-041927051365_DN
DrugCarbenoxolone disodium salt [7421-40-1]; Down 200; 6.6uM; MCF7; HT_HG-U133A

SULT1B1 PSME4 SMARCC1 NDUFA5 DNMT3A

3.22e-041937054173_DN
DrugSTOCK1N-35874; Up 200; 14uM; PC3; HT_HG-U133A

MGAT4B GEMIN4 SMARCC1 PLD3 TXLNG

3.37e-041957056583_UP
DrugPHA-00767505E [723337-45-9]; Down 200; 10uM; PC3; HT_HG-U133A

BRIP1 RABGAP1 CTSK ALDH7A1 DNMT3A

3.45e-041967056591_DN
DrugMethionine sulfoximine (L) [15985-39-4]; Down 200; 22.2uM; MCF7; HT_HG-U133A

HPX DCBLD2 ALDH7A1 MIR9-1HG DNMT3A

3.45e-041967054151_DN
DrugBezafibrate [41859-67-0]; Up 200; 11uM; MCF7; HT_HG-U133A

SULT1B1 TRPM8 PLD3 NOS1AP DNMT3A

3.54e-041977052630_UP
Drug(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; MCF7; HT_HG-U133A

ADGB HPX DCBLD2 STAT4 NOS1AP

3.54e-041977053531_UP
DrugPHA-00851261E [724719-49-7]; Up 200; 1uM; PC3; HT_HG-U133A

ATAD5 HPX RABGAP1 FERMT2 STAT4

3.62e-041987054333_UP
DrugDydrogesterone [152-62-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A

RABGAP1 NDUFA5 MIR9-1HG NOS1AP DNMT3A

3.62e-041987054836_UP
Diseaserheumatoid arthritis (implicated_via_orthology)

KMT2C NCF1 NCF1C NCF1B

1.19e-0812674DOID:7148 (implicated_via_orthology)
Diseasechronic granulomatous disease (implicated_via_orthology)

NCF1 NCF1C NCF1B

1.12e-075673DOID:3265 (implicated_via_orthology)
DiseaseC-X-C motif chemokine 6 measurement

VANGL2 MIR9-1HG NOS1AP

6.13e-0616673EFO_0008059
DiseaseHIV Coinfection

ARHGDIA PSME4 PSMD13 LYN

9.06e-05103674C4505456
DiseaseHIV Infections

ARHGDIA PSME4 PSMD13 LYN

9.06e-05103674C0019693
DiseaseSjogren's Syndrome

NCF1 STAT4

3.90e-0413672C1527336
DiseaseSicca Syndrome

NCF1 STAT4

3.90e-0413672C0086981
Diseaselevel of C-X-C motif chemokine 3 in blood serum

MIR9-1HG NOS1AP

5.23e-0415672OBA_2041208
Diseasehepatocellular carcinoma (is_marker_for)

SMARCC1 RICTOR ALDH7A1 DNMT3A RAD21

6.15e-04301675DOID:684 (is_marker_for)
DiseaseLeukemia, Myelocytic, Acute

KMT2C BRIP1 DNMT3A RAD21

6.56e-04173674C0023467
DiseaseCarcinoma of lung

RICTOR RAD21

1.25e-0323672C0684249
DiseaseAcute monocytic leukemia

BRIP1 DNMT3A

1.59e-0326672C0023465
Diseasesystemic scleroderma, systemic lupus erythematosus

SAMD9L STAT4

1.59e-0326672EFO_0000717, MONDO_0007915
DiseaseSezary Syndrome

KMT2C DNMT3A

1.72e-0327672C0036920
DiseaseIniencephaly

VANGL2 RRM1

1.85e-0328672C0152234
DiseaseTethered Cord Syndrome

VANGL2 RRM1

1.85e-0328672C0080218
DiseaseSpinal Cord Myelodysplasia

VANGL2 RRM1

1.85e-0328672C0344479
DiseaseExencephaly

VANGL2 RRM1

1.85e-0328672C0266453
DiseaseNeurenteric Cyst

VANGL2 RRM1

1.85e-0328672C0027806
DiseaseAcrania

VANGL2 RRM1

1.85e-0328672C0702169
DiseaseDiastematomyelia

VANGL2 RRM1

1.85e-0328672C0011999
DiseaseCraniorachischisis

VANGL2 RRM1

1.98e-0329672C0152426
DiseaseStrabismus

DNAH5 SMYD3

1.98e-0329672HP_0000486
DiseaseNeural Tube Defects

VANGL2 RRM1

2.12e-0330672C0027794
Diseasemean reticulocyte volume

BRIP1 CHTF18 ACSF3 RRM1 LYN HPS3 NOS1AP

2.21e-03799677EFO_0010701

Protein segments in the cluster

PeptideGeneStartEntry
HKERWLAKQWTLVSE

VANGL2

451

Q9ULK5
ILDTHWELWKKTHRK

CTSK

21

P43235
LAIKKLHSWLKDWKR

ATAD5

1071

Q96QE3
KWLKLWDLVVFGHER

CHTF18

306

Q8WVB6
IKSTREEKEWWIRSK

AGAP9

601

Q5VTM2
RKKDPVLLLHWWKEI

EIF2AK3

511

Q9NZJ5
WLARWKREAEKKAKV

DNMT3A

206

Q9Y6K1
TVKKAREAWKIWADI

ALDH7A1

91

P49419
VWKKWQLTKGLRDVA

ADGB

1471

Q8N7X0
DKKHVDWVKAYLSIW

CAP1

176

Q01518
LVHKWAWTKDDVILH

ACSF3

226

Q4G176
AWLSWETKKKNVLHL

MIR9-1HG

136

Q13536
WENDWLKKEVAIHRK

CCDC83

216

Q8IWF9
WWVSKHIKKPIRSTV

ARPC1A

131

Q92747
KIWLAAHWEKKLTKA

RAD21L1

16

Q9H4I0
KIWLAAHWDKKLTKA

RAD21

16

O60216
HELIKLNWLLAKALW

RIMBP3B

371

A6NNM3
HELIKLNWLLAKALW

RIMBP3C

371

A6NJZ7
KILETWGELLSKWHL

RABGAP1

536

Q9Y3P9
IEAWKAAEKKARWVL

PLD3

26

Q8IV08
KWKKWSIHIVIPKGT

KMT2C

4356

Q8NEZ4
KPIDWLLDHILWVKV

MGAT4B

326

Q9UQ53
LRNKDVKGALWKVLW

OR2Y1

291

Q8NGV0
IHKLLDGWWVIRKDD

NCF1

256

P14598
KLEVLDHSKRWWLVK

EPS8L3

476

Q8TE67
QHWAKSEKVKLWEVS

NKIRAS2

136

Q9NYR9
LWETRVKKHKAWQKK

LRRC2

16

Q9BYS8
GLLLWQSWLELKKMH

EBPL

181

Q9BY08
VWHRLEELYTKKLWH

PSMD13

21

Q9UNM6
KWEEIKKLKASLWAL

RICTOR

916

Q6R327
VIHKLLDGWWVIRKD

NCF1B

256

A6NI72
VIHKLLDGWWVIRKD

NCF1C

231

A8MVU1
LEKLKERWLSTGLWH

BRIP1

701

Q9BX63
LWWAAKELRRTKKLS

CFAP298

191

P57076
KTDHLSWEWNLTIKK

ARHGDIA

186

P52565
IWKKRWDKFIADVAT

ADA2

496

Q9NZK5
KVLEEHGEWWKAKSL

LYN

91

P07948
HGEWWKAKSLLTKKE

LYN

96

P07948
HTVVLWDWKKGEKLS

EML5

796

Q05BV3
LILVCAWHWRNRKKK

DCBLD2

546

Q96PD2
QAWKEVRLHKTTWLR

HAUS4

66

Q9H6D7
LLLLQKKEWTWDESK

NOS1AP

91

O75052
EKKRTWLLKTHWTLD

FERMT2

66

Q96AC1
LQEEDKLHIMKEKWW

GRIK3

786

Q13003
RTVKKEWQAAWLLKA

DERA

36

Q9Y315
VKRAELWDTWKVAHL

NOC4L

231

Q9BVI4
WRKTLRAKKGEHIWI

DNAH5

2321

Q8TE73
KWILSEKEWEREKAV

MROH2A

956

A6NES4
KGEFVWKSHKWDREL

HPX

71

P02790
ELKEENRTLWWKKLL

HPS3

926

Q969F9
HELIKLNWLLAKALW

RIMBP3

371

Q9UFD9
IKDWTKEHVKKWVNE

SAMD9L

11

Q8IVG5
LWSWMKLETIILSKL

PRORY

151

Q9H606
LLSWKLERVFKDWAK

SCP2D1

141

Q9UJQ7
GSDNLLVILKRKWWK

SLC35F2

96

Q8IXU6
HELNLARKMREWKLW

NDUFA5

86

Q16718
KPWKVHVKWILDTDI

SMARCC1

261

Q92922
KKIEELKAHWKWEQV

SMYD3

291

Q9H7B4
HVKNWWKKKEEHPIL

SULT1B1

176

O43704
LRKWSHSLQKRWIEV

SERPINA9

291

Q86WD7
IHILKIMWKWIGELQ

CLCA1

896

A8K7I4
KKKADWALRWIADRK

RRM2B

166

Q7LG56
AIMEHKELLKVPWDW

SLC35F1

266

Q5T1Q4
TDLWDWKVLKEKIAK

RRM1

576

P23921
DKHITIEDLWKRWKT

STIM2

116

Q9P246
WTWLEAILDLIKKHI

STAT4

551

Q14765
RKLLWAIHHWKKIKK

TBC1D15

226

Q8TC07
KHWTFEKVEKLWELL

PSME4

1391

Q14997
GKFLLKVDSKLWHWL

TMEM245

431

Q9H330
SWIKWLKEILECSHL

TRPM8

376

Q7Z2W7
KLEKETIIWRTKWEN

TXLNG

391

Q9NUQ3
ILVILKEWTSKLWHR

VMP1

61

Q96GC9
VWIKSLSWLHRKLEQ

GEMIN4

751

P57678
WLRTDKDWKAGKTKI

MYO7B

731

Q6PIF6