Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glucosidase activity	MGAM SI KL	6.86e-05	15	109	3	GO:0015926
GeneOntologyMolecularFunction	testosterone 16-alpha-hydroxylase activity	CYP3A5 CYP3A43	1.76e-04	4	109	2	GO:0008390
GeneOntologyMolecularFunction	testosterone 6-beta-hydroxylase activity	CYP3A5 CYP3A43	2.92e-04	5	109	2	GO:0050649
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	MGAM SI	2.92e-04	5	109	2	GO:0004558
GeneOntologyMolecularFunction	vitamin D 23-hydroxylase activity	CYP3A5 CYP3A43	2.92e-04	5	109	2	GO:0062179
GeneOntologyMolecularFunction	1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity	CYP3A5 CYP3A43	2.92e-04	5	109	2	GO:0062181
GeneOntologyMolecularFunction	vitamin D3 25-hydroxylase activity	CYP3A5 CYP3A43	4.37e-04	6	109	2	GO:0030343
GeneOntologyMolecularFunction	vitamin D 24-hydroxylase activity	CYP3A5 CYP3A43	4.37e-04	6	109	2	GO:0070576
GeneOntologyMolecularFunction	vitamin D 25-hydroxylase activity	CYP3A5 CYP3A43	6.09e-04	7	109	2	GO:0070643
GeneOntologyMolecularFunction	alpha-glucosidase activity	MGAM SI	6.09e-04	7	109	2	GO:0090599
GeneOntologyMolecularFunction	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor	CYP3A5 CYP3A43	8.09e-04	8	109	2	GO:0033695
GeneOntologyMolecularFunction	caffeine oxidase activity	CYP3A5 CYP3A43	8.09e-04	8	109	2	GO:0034875
GeneOntologyMolecularFunction	estrogen 2-hydroxylase activity	CYP3A5 CYP3A43	8.09e-04	8	109	2	GO:0101021
GeneOntologyMolecularFunction	aromatase activity	CYP2J2 CYP3A5 CYP3A43	9.12e-04	35	109	3	GO:0070330
GeneOntologyMolecularFunction	estrogen 16-alpha-hydroxylase activity	CYP3A5 CYP3A43	1.57e-03	11	109	2	GO:0101020
GeneOntologyMolecularFunction	cell adhesion molecule binding	EZR FLNB PRTG IST1 RDX ARHGAP1 TENM1 ATIC DMD ARHGAP18	1.63e-03	599	109	10	GO:0050839
GeneOntologyBiologicalProcess	cell morphogenesis	EZR FLNB LPAR3 PRTG NYAP2 KIF1A IST1 RDX FRYL RILPL1 TIAM2 MYO3A GDF7 TIAM1 PTPRS HECW2 PRKCQ DMD ARHGAP18 PLXNA1 CNP SEMA3E	3.31e-07	1194	111	22	GO:0000902
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection organization	EZR LPAR3 KIF1A MAP4 STMN2 IST1 RDX TIAM2 LRIG2 MYO3A TIAM1 PTPRS HECW2 TENM1 PRKCQ DMD PLXNA1	2.74e-06	846	111	17	GO:0120035
GeneOntologyBiologicalProcess	regulation of cell projection organization	EZR LPAR3 KIF1A MAP4 STMN2 IST1 RDX TIAM2 LRIG2 MYO3A TIAM1 PTPRS HECW2 TENM1 PRKCQ DMD PLXNA1	3.57e-06	863	111	17	GO:0031344
GeneOntologyBiologicalProcess	neuron projection development	LPAR3 PRTG NYAP2 KIF1A MAP4 STMN2 IST1 FRYL TIAM2 LRIG2 MYO3A GDF7 TIAM1 PTPRS HECW2 PRKCQ DMD PLXNA1 CNP SEMA3E	1.55e-05	1285	111	20	GO:0031175
GeneOntologyBiologicalProcess	neuron projection morphogenesis	LPAR3 PRTG NYAP2 KIF1A IST1 TIAM2 GDF7 TIAM1 PTPRS HECW2 PRKCQ DMD PLXNA1 CNP SEMA3E	2.59e-05	802	111	15	GO:0048812
GeneOntologyBiologicalProcess	regulation of anatomical structure size	EZR LPAR3 OGT CYP2J2 IST1 RDX MYO3A GRK2 PIK3C2A PTPRS TENM1 VAV3 ARHGAP18	2.82e-05	618	111	13	GO:0090066
GeneOntologyBiologicalProcess	neuron development	LPAR3 PRTG NYAP2 KIF1A MAP4 STMN2 IST1 FRYL TIAM2 LRIG2 MYO3A GDF7 TIAM1 PTPRS HECW2 TENM1 PRKCQ DMD PLXNA1 CNP SEMA3E	3.09e-05	1463	111	21	GO:0048666
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	LPAR3 PRTG NYAP2 KIF1A IST1 TIAM2 GDF7 TIAM1 PTPRS HECW2 PRKCQ DMD PLXNA1 CNP SEMA3E	3.30e-05	819	111	15	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	LPAR3 PRTG NYAP2 KIF1A IST1 TIAM2 GDF7 TIAM1 PTPRS HECW2 PRKCQ DMD PLXNA1 CNP SEMA3E	3.64e-05	826	111	15	GO:0048858
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	LPAR3 PRTG KIF1A IST1 TIAM2 MYO3A GDF7 TIAM1 PTPRS HECW2 PRKCQ PLXNA1 CNP SEMA3E	4.89e-05	748	111	14	GO:0048667
GeneOntologyBiologicalProcess	olfactory nerve morphogenesis	DMD PLXNA1	8.58e-05	3	111	2	GO:0021627
GeneOntologyBiologicalProcess	regulation of cellular component size	EZR LPAR3 OGT IST1 RDX MYO3A PTPRS TENM1 VAV3 ARHGAP18	1.02e-04	426	111	10	GO:0032535
GeneOntologyBiologicalProcess	epithelial cell development	EZR FLNB MYO1E ABCA12 RDX RILPL1 PTPRS DMD	1.05e-04	269	111	8	GO:0002064
GeneOntologyBiologicalProcess	disaccharide catabolic process	MGAM SI	1.71e-04	4	111	2	GO:0046352
GeneOntologyBiologicalProcess	axon development	LPAR3 PRTG IST1 TIAM2 LRIG2 GDF7 TIAM1 PTPRS PRKCQ PLXNA1 CNP SEMA3E	1.77e-04	642	111	12	GO:0061564
GeneOntologyBiologicalProcess	regulation of cell size	EZR LPAR3 OGT IST1 RDX PTPRS VAV3	2.18e-04	225	111	7	GO:0008361
GeneOntologyBiologicalProcess	axonogenesis	LPAR3 PRTG IST1 TIAM2 GDF7 TIAM1 PTPRS PRKCQ PLXNA1 CNP SEMA3E	2.40e-04	566	111	11	GO:0007409
GeneOntologyBiologicalProcess	peptidyl-serine phosphorylation	OGT ATR STOX1 MYO3A GRK2 TENM1 PRKCQ DMD	2.58e-04	307	111	8	GO:0018105
GeneOntologyBiologicalProcess	positive regulation of chondrocyte differentiation	SOX5 GDF5 GDF6	2.83e-04	24	111	3	GO:0032332
GeneOntologyBiologicalProcess	alkaloid catabolic process	CYP3A5 CYP3A43	2.84e-04	5	111	2	GO:0009822
GeneOntologyBiologicalProcess	regulation of collateral sprouting	LPAR3 IST1 PTPRS	3.20e-04	25	111	3	GO:0048670
GeneOntologyBiologicalProcess	peptidyl-serine modification	OGT ATR STOX1 MYO3A GRK2 TENM1 PRKCQ DMD	3.33e-04	319	111	8	GO:0018209
GeneOntologyBiologicalProcess	positive regulation of cell projection organization	LPAR3 STMN2 IST1 TIAM2 MYO3A TIAM1 TENM1 PRKCQ DMD PLXNA1	3.37e-04	494	111	10	GO:0031346
GeneOntologyBiologicalProcess	positive regulation of axonogenesis	LPAR3 IST1 TIAM2 TIAM1 PLXNA1	3.80e-04	114	111	5	GO:0050772
GeneOntologyBiologicalProcess	regulation of small GTPase mediated signal transduction	OGT RDX GMIP TIAM2 ARHGAP1 TIAM1 VAV3 ARHGAP18	4.43e-04	333	111	8	GO:0051056
GeneOntologyBiologicalProcess	regulation of neuron differentiation	SOX5 GDF5 GDF6 GDF7 HOXD3 TIAM1 DMD	4.63e-04	255	111	7	GO:0045664
GeneOntologyBiologicalProcess	regulation of neuron projection development	LPAR3 KIF1A STMN2 IST1 TIAM2 LRIG2 TIAM1 PTPRS HECW2 DMD PLXNA1	4.64e-04	612	111	11	GO:0010975
GeneOntologyBiologicalProcess	positive regulation of neuron differentiation	GDF5 GDF6 GDF7 HOXD3 DMD	5.38e-04	123	111	5	GO:0045666
GeneOntologyBiologicalProcess	gonadotrophin-releasing hormone neuronal migration to the hypothalamus	PLXNA1 SEMA3E	5.92e-04	7	111	2	GO:0021828
GeneOntologyBiologicalProcess	hypothalamic tangential migration using cell-axon interactions	PLXNA1 SEMA3E	5.92e-04	7	111	2	GO:0021856
GeneOntologyBiologicalProcess	regulation of axonogenesis	LPAR3 IST1 TIAM2 TIAM1 PTPRS PLXNA1	6.06e-04	192	111	6	GO:0050770
GeneOntologyCellularComponent	cluster of actin-based cell projections	EZR FLNB MYO1E RDX SI MYO3A TIAM1 ENPEP	2.23e-05	223	109	8	GO:0098862
Domain	-	RGPD4 EZR KIF1A RDX TIAM2 PTPN4 AFAP1L2 GRK2 TIAM1 VAV3 MTMR9	1.80e-05	391	109	11	2.30.29.30
Domain	PH_dom-like	RGPD4 EZR KIF1A RDX TIAM2 PTPN4 AFAP1L2 GRK2 TIAM1 VAV3 MTMR9	3.95e-05	426	109	11	IPR011993
Domain	ERM_C_dom	EZR RDX	2.01e-04	4	109	2	IPR011259
Domain	Glyco_hydro_31_CS	MGAM SI	2.01e-04	4	109	2	IPR030459
Domain	Gal_mutarotase_N	MGAM SI	2.01e-04	4	109	2	IPR031727
Domain	ERM	EZR RDX	2.01e-04	4	109	2	PF00769
Domain	NtCtMGAM_N	MGAM SI	2.01e-04	4	109	2	PF16863
Domain	ERM	EZR RDX	2.01e-04	4	109	2	IPR011174
Domain	Ez/rad/moesin-like	EZR RDX PTPN4	2.38e-04	21	109	3	IPR000798
Domain	GLYCOSYL_HYDROL_F31_2	MGAM SI	3.34e-04	5	109	2	PS00707
Domain	Cyt_P450_E_grp-II	CYP3A5 CYP3A43	3.34e-04	5	109	2	IPR002402
Domain	FERM_CS	EZR RDX PTPN4	3.58e-04	24	109	3	IPR019747
Domain	FERM_C	EZR RDX PTPN4	4.56e-04	26	109	3	PF09380
Domain	Cyt_P450_E_CYP3A	CYP3A5 CYP3A43	4.99e-04	6	109	2	IPR008072
Domain	Glyco_hydro_31_AS	MGAM SI	4.99e-04	6	109	2	IPR030458
Domain	FERM_PH-like_C	EZR RDX PTPN4	5.11e-04	27	109	3	IPR018980
Domain	FERM_C	EZR RDX PTPN4	5.11e-04	27	109	3	SM01196
Domain	TGFb_propeptide	GDF5 GDF6 GDF7	5.70e-04	28	109	3	PF00688
Domain	TGF-b_N	GDF5 GDF6 GDF7	5.70e-04	28	109	3	IPR001111
Domain	Glyco_hydro_31	MGAM SI	6.95e-04	7	109	2	IPR000322
Domain	Glyco_hydro_31	MGAM SI	6.95e-04	7	109	2	PF01055
Domain	Moesin_tail	EZR RDX	6.95e-04	7	109	2	IPR008954
Domain	RBD	TIAM2 TIAM1	6.95e-04	7	109	2	SM00455
Domain	RBD_dom	TIAM2 TIAM1	6.95e-04	7	109	2	IPR003116
Domain	RBD	TIAM2 TIAM1	6.95e-04	7	109	2	PS50898
Domain	GLYCOSYL_HYDROL_F31_1	MGAM SI	6.95e-04	7	109	2	PS00129
Domain	TGF-beta-rel	GDF5 GDF6 GDF7	8.48e-04	32	109	3	IPR015615
Domain	TGFb_CS	GDF5 GDF6 GDF7	8.48e-04	32	109	3	IPR017948
Domain	P_TREFOIL_1	MGAM SI	9.24e-04	8	109	2	PS00025
Domain	Trefoil	MGAM SI	9.24e-04	8	109	2	PF00088
Domain	P_trefoil_CS	MGAM SI	9.24e-04	8	109	2	IPR017957
Domain	FERM_N	EZR RDX PTPN4	9.29e-04	33	109	3	IPR018979
Domain	FERM_N	EZR RDX PTPN4	9.29e-04	33	109	3	PF09379
Domain	P_TREFOIL_2	MGAM SI	1.18e-03	9	109	2	PS51448
Domain	PD	MGAM SI	1.18e-03	9	109	2	SM00018
Domain	TGF-b_C	GDF5 GDF6 GDF7	1.30e-03	37	109	3	IPR001839
Domain	TGF_BETA_1	GDF5 GDF6 GDF7	1.30e-03	37	109	3	PS00250
Domain	TGFB	GDF5 GDF6 GDF7	1.30e-03	37	109	3	SM00204
Domain	TGF_BETA_2	GDF5 GDF6 GDF7	1.30e-03	37	109	3	PS51362
Domain	TGF_beta	GDF5 GDF6 GDF7	1.30e-03	37	109	3	PF00019
Domain	GDS_CDC24_CS	TIAM2 TIAM1 VAV3	1.52e-03	39	109	3	IPR001331
Domain	Rho_GTPase_activation_prot	GMIP ARHGAP1 ARHGAP18 PLXNA1	1.76e-03	88	109	4	IPR008936
Domain	-	MGAM SI	1.79e-03	11	109	2	4.10.110.10
Domain	P_trefoil_dom	MGAM SI	2.14e-03	12	109	2	IPR000519
Domain	PH	KIF1A TIAM2 AFAP1L2 GRK2 TIAM1 VAV3	2.26e-03	229	109	6	PF00169
Domain	Cyt_P450_E_grp-I	CYP2J2 CYP3A5 CYP3A43	2.30e-03	45	109	3	IPR002401
Domain	FERM_M	EZR RDX PTPN4	2.45e-03	46	109	3	PF00373
Domain	TPR-like_helical_dom	RGPD4 OGT ATR USP28 EIF3L ZC3H7B	2.46e-03	233	109	6	IPR011990
Domain	-	EZR RDX PTPN4	2.93e-03	49	109	3	1.20.80.10
Domain	FERM_central	EZR RDX PTPN4	2.93e-03	49	109	3	IPR019748
Domain	FERM_domain	EZR RDX PTPN4	2.93e-03	49	109	3	IPR000299
Domain	-	AOX1 MOCS2	2.93e-03	14	109	2	3.10.20.30
Domain	Beta-grasp_dom	AOX1 MOCS2	2.93e-03	14	109	2	IPR012675
Domain	FERM/acyl-CoA-bd_prot_3-hlx	EZR RDX PTPN4	3.10e-03	50	109	3	IPR014352
Domain	FERM_1	EZR RDX PTPN4	3.10e-03	50	109	3	PS00660
Domain	FERM_2	EZR RDX PTPN4	3.10e-03	50	109	3	PS00661
Domain	FERM_3	EZR RDX PTPN4	3.10e-03	50	109	3	PS50057
Domain	Band_41_domain	EZR RDX PTPN4	3.10e-03	50	109	3	IPR019749
Domain	B41	EZR RDX PTPN4	3.10e-03	50	109	3	SM00295
Domain	PI3/4_kinase_CS	ATR PIK3C2A	3.37e-03	15	109	2	IPR018936
Domain	Glycoside_hydrolase_SF	MGAM SI KL	3.66e-03	53	109	3	IPR017853
Domain	Cyt_P450_CS	CYP2J2 CYP3A5 CYP3A43	3.66e-03	53	109	3	IPR017972
Domain	-	ATR PIK3C2A	3.84e-03	16	109	2	1.10.1070.11
Domain	PI3Kc	ATR PIK3C2A	3.84e-03	16	109	2	SM00146
Domain	Gal_mutarotase_SF_dom	MGAM SI	4.33e-03	17	109	2	IPR011013
Domain	Ubiquitin-rel_dom	EZR RDX PTPN4 PIK3C2A UHRF1	4.50e-03	184	109	5	IPR029071
Domain	CYTOCHROME_P450	CYP2J2 CYP3A5 CYP3A43	4.50e-03	57	109	3	PS00086
Domain	C1_1	GMIP VAV3 PRKCQ	4.50e-03	57	109	3	PF00130
Domain	-	CYP2J2 CYP3A5 CYP3A43	4.73e-03	58	109	3	1.10.630.10
Domain	p450	CYP2J2 CYP3A5 CYP3A43	4.73e-03	58	109	3	PF00067
Domain	PI3_PI4_kinase	ATR PIK3C2A	4.86e-03	18	109	2	PF00454
Domain	PI3_4_KINASE_1	ATR PIK3C2A	4.86e-03	18	109	2	PS00915
Domain	PI3_4_KINASE_2	ATR PIK3C2A	4.86e-03	18	109	2	PS00916
Domain	PI3/4_kinase_cat_dom	ATR PIK3C2A	4.86e-03	18	109	2	IPR000403
Domain	PI3_4_KINASE_3	ATR PIK3C2A	4.86e-03	18	109	2	PS50290
Domain	Cyt_P450	CYP2J2 CYP3A5 CYP3A43	5.20e-03	60	109	3	IPR001128
Domain	RhoGAP	GMIP ARHGAP1 ARHGAP18	5.70e-03	62	109	3	SM00324
Domain	PH	KIF1A TIAM2 AFAP1L2 GRK2 TIAM1 VAV3	5.81e-03	278	109	6	SM00233
Pathway	PID_RAC1_REG_PATHWAY	TIAM2 ARHGAP1 TIAM1 VAV3	8.90e-05	38	88	4	M241
Pathway	KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY_BMP_ANTAGONIST	GDF5 GDF6 GDF7	1.01e-04	15	88	3	M47824
Pubmed	Isolation of zebrafish gdf7 and comparative genetic mapping of genes belonging to the growth/differentiation factor 5, 6, 7 subgroup of the TGF-beta superfamily.	GDF5 GDF6 GDF7	3.25e-08	3	112	3	10022976
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	EZR FLNB OGT KIF1A MYO1E USP28 PEG3 ZNF343 IST1 RDX VPS26A RILPL1 ARHGAP1 SNRNP48 TIAM1 ATIC ALPL ZNF292	1.55e-07	1285	112	18	35914814
Pubmed	Temporomandibular joint formation requires two distinct hedgehog-dependent steps.	SOX5 GDF5 GDF6 GDF7	5.85e-07	21	112	4	19815519
Pubmed	Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes.	GDF5 GDF6 GDF7	1.13e-06	7	112	3	12606286
Pubmed	Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily.	GDF5 GDF6 GDF7	1.13e-06	7	112	3	8145850
Pubmed	Molecular Characterization of the Genital Organizer: Gene Expression Profile of the Mouse Urethral Plate Epithelium.	KRT8 CYP3A5 CYP3A43 DMD	1.69e-06	27	112	4	27173853
Pubmed	Radixin regulates cell migration and cell-cell adhesion through Rac1.	EZR RDX VAV3	2.69e-06	9	112	3	22467863
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FLNB COL8A1 KIF1A SLC26A9 STOX1 TMEM132B AFAP1L2 HECW2 EIF3L CEP295 ATIC MTMR9	4.73e-06	736	112	12	29676528
Pubmed	Neuronal patterning by BMPs: a requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord.	GDF5 GDF6 GDF7	7.00e-06	12	112	3	9808626
Pubmed	Podoplanin regulates mammary stem cell function and tumorigenesis by potentiating Wnt/β-catenin signaling.	EZR KRT8 RDX	7.00e-06	12	112	3	29361573
Pubmed	Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.	FLNB PRTG VAV3 ARHGAP18 ALPL	8.46e-06	85	112	5	23648065
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	EZR MGAM FLNB KRT8 IST1 RDX SI ARHGAP1 KL PTPRS ATIC ENPEP CNP ALPL	9.14e-06	1070	112	14	23533145
Pubmed	BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells.	GDF6 GDF7	1.03e-05	2	112	2	20334610
Pubmed	Perspectives for Ezrin and Radixin in Astrocytes: Kinases, Functions and Pathology.	EZR RDX	1.03e-05	2	112	2	31382374
Pubmed	PKC theta ablation improves healing in a mouse model of muscular dystrophy.	PRKCQ DMD	1.03e-05	2	112	2	22348094
Pubmed	Pharmacological Inhibition of PKCθ Counteracts Muscle Disease in a Mouse Model of Duchenne Muscular Dystrophy.	PRKCQ DMD	1.03e-05	2	112	2	28089792
Pubmed	Roles of STEF/Tiam1, guanine nucleotide exchange factors for Rac1, in regulation of growth cone morphology.	TIAM2 TIAM1	1.03e-05	2	112	2	14550769
Pubmed	Cartilage morphogenesis: role of bone and cartilage morphogenetic proteins, homeobox genes and extracellular matrix.	GDF5 GDF6	1.03e-05	2	112	2	9057810
Pubmed	Crystallographic characterization of the membrane-targeting domains of the Rac-specific guanine nucleotide-exchange factors Tiam1 and Tiam2.	TIAM2 TIAM1	1.03e-05	2	112	2	18997336
Pubmed	ERM proteins and merlin: integrators at the cell cortex.	EZR PRKCQ	1.03e-05	2	112	2	12154370
Pubmed	Interaction between the α-glucosidases, sucrase-isomaltase and maltase-glucoamylase, in human intestinal brush border membranes and its potential impact on disaccharide digestion.	MGAM SI	1.03e-05	2	112	2	36968271
Pubmed	Lack of PKCθ Promotes Regenerative Ability of Muscle Stem Cells in Chronic Muscle Injury.	PRKCQ DMD	1.03e-05	2	112	2	32023816
Pubmed	Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models.	DMD ALPL	1.03e-05	2	112	2	19151073
Pubmed	Contribution of the Individual Small Intestinal α-Glucosidases to Digestion of Unusual α-Linked Glycemic Disaccharides.	MGAM SI	1.03e-05	2	112	2	27480812
Pubmed	Emerging role for ERM proteins in cell adhesion and migration.	EZR RDX	1.03e-05	2	112	2	21343695
Pubmed	Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy.	KL DMD	1.03e-05	2	112	2	27154199
Pubmed	Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth.	TIAM2 TIAM1	1.03e-05	2	112	2	11707441
Pubmed	Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains.	MGAM SI	1.03e-05	2	112	2	20356844
Pubmed	G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton.	EZR GRK2	1.03e-05	2	112	2	15843435
Pubmed	Radixin is a novel member of the band 4.1 family.	EZR RDX	1.03e-05	2	112	2	1955455
Pubmed	Mapping of ezrin dimerization using yeast two-hybrid screening.	EZR RDX	1.03e-05	2	112	2	9501018
Pubmed	Targeting early PKCθ-dependent T-cell infiltration of dystrophic muscle reduces disease severity in a mouse model of muscular dystrophy.	PRKCQ DMD	1.03e-05	2	112	2	29214629
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RGPD4 EZR NYAP2 AGO2 OGT USP28 RDX TMEM132B LRIG2 SH3PXD2B HOOK3 PTPRS CNP	1.41e-05	963	112	13	28671696
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DPP6 FLNB AGO2 OGT MYO1E MAP4 RDX CHD3 NDUFS8 GRK2 PTPRS HECW2 EIF3L HADHB DMD CNP	1.43e-05	1431	112	16	37142655
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	FLNB AOX1 IST1 RDX TIAM2 ARHGAP1 KL PTGR1 PIK3C2A ATIC ENPEP CNP ALPL	2.46e-05	1016	112	13	19056867
Pubmed	VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland.	EZR KRT8 RDX	2.56e-05	18	112	3	31068622
Pubmed	SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia.	EZR KRT8 RDX	3.03e-05	19	112	3	21965329
Pubmed	The ezrin-like family of tyrosine kinase substrates: receptor-specific pattern of tyrosine phosphorylation and relationship to malignant transformation.	EZR RDX	3.08e-05	3	112	2	8479753
Pubmed	Characterization of lens fiber cell triton insoluble fraction reveals ERM (ezrin, radixin, moesin) proteins as major cytoskeletal-associated proteins.	EZR RDX	3.08e-05	3	112	2	18261459
Pubmed	Ezrin, radixin, and moesin are phosphorylated in response to 2-methoxyestradiol and modulate endothelial hyperpermeability.	EZR RDX	3.08e-05	3	112	2	21659656
Pubmed	Expression, localization, and binding activity of the ezrin/radixin/moesin proteins in the mouse testis.	EZR RDX	3.08e-05	3	112	2	19064715
Pubmed	Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins.	EZR RDX	3.08e-05	3	112	2	27029001
Pubmed	Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement.	EZR RDX	3.08e-05	3	112	2	21864676
Pubmed	Downregulation of mouse hepatic CYP3A protein by 3-methylcholanthrene does not require cytochrome P450-dependent metabolism.	CYP3A5 CYP3A43	3.08e-05	3	112	2	23846873
Pubmed	Differential expression of ezrin/radixin/moesin (ERM) and ERM-associated adhesion molecules in the blastocyst and uterus suggests their functions during implantation.	EZR RDX	3.08e-05	3	112	2	14613898
Pubmed	Regulation of the expression of two female-predominant CYP3A mRNAs (CYP3A41 and CYP3A44) in mouse liver by sex and growth hormones.	CYP3A5 CYP3A43	3.08e-05	3	112	2	12147261
Pubmed	Inhibition of cell adhesion by phosphorylated Ezrin/Radixin/Moesin.	EZR RDX	3.08e-05	3	112	2	26555866
Pubmed	Mouse liver cytochrome P-450 (P-450IIIAM1): its cDNA cloning and inducibility by dexamethasone.	CYP3A5 CYP3A43	3.08e-05	3	112	2	1339292
Pubmed	Predominantly neuronal expression of cytochrome P450 isoforms CYP3A11 and CYP3A13 in mouse brain.	CYP3A5 CYP3A43	3.08e-05	3	112	2	12617959
Pubmed	Partial characterization of murine intestinal maltase-glucoamylase.	MGAM SI	3.08e-05	3	112	2	12150962
Pubmed	Human ezrin-moesin-radixin proteins modulate hepatitis C virus infection.	EZR RDX	3.08e-05	3	112	2	23703860
Pubmed	UV-induced activation of ATR is mediated by UHRF2.	ATR UHRF1	3.08e-05	3	112	2	33848395
Pubmed	Pseudomonas aeruginosa ExoS ADP-ribosyltransferase inhibits ERM phosphorylation.	EZR RDX	3.08e-05	3	112	2	16889625
Pubmed	Effect of knockdown of ezrin, radixin, and moesin on P-glycoprotein function in HepG2 cells.	EZR RDX	3.08e-05	3	112	2	21837648
Pubmed	Ezrin and moesin function together to promote T cell activation.	EZR RDX	3.08e-05	3	112	2	19124745
Pubmed	Intergenic mRNA molecules resulting from trans-splicing.	CYP3A5 CYP3A43	3.08e-05	3	112	2	11726664
Pubmed	Alkaline phosphatase, cytokeratin 7, cytokeratin 8 in the diagnosis of primary lung adenocarcinoma from 148 pleura fluids specimens.	KRT8 ALPL	3.08e-05	3	112	2	19419944
Pubmed	Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.	EZR RDX	3.08e-05	3	112	2	22132106
Pubmed	Ezrin and radixin both regulate the apical membrane localization of ABCC2 (MRP2) in human intestinal epithelial Caco-2 cells.	EZR RDX	3.08e-05	3	112	2	17825285
Pubmed	High fat diet induced obesity is mitigated in Cyp3a-null female mice.	CYP3A5 CYP3A43	3.08e-05	3	112	2	29738703
Pubmed	A novel female-specific member of the CYP3A gene subfamily in the mouse liver.	CYP3A5 CYP3A43	3.08e-05	3	112	2	10775455
Pubmed	Concordant up-regulation of cytochrome P450 Cyp3a11, testosterone oxidation and androgen receptor expression in mouse brain after xenobiotic treatment.	CYP3A5 CYP3A43	3.08e-05	3	112	2	19226368
Pubmed	Dynamic patterns of histone methylation are associated with ontogenic expression of the Cyp3a genes during mouse liver maturation.	CYP3A5 CYP3A43	3.08e-05	3	112	2	19188337
Pubmed	Ezrin-radixin-moesin family proteins are involved in parvovirus replication and spreading.	EZR RDX	3.08e-05	3	112	2	19321616
Pubmed	Deciphering brain-specific transcriptomic expression of Ezr, Rad and Msn genes in the development of Mus musculus.	EZR RDX	3.08e-05	3	112	2	29906485
Pubmed	Activation of PKC induces leukocyte adhesion by the dephosphorylation of ERM.	EZR RDX	3.08e-05	3	112	2	31843195
Pubmed	Specific interaction of the actin-binding domain of dystrophin with intermediate filaments containing keratin 19.	KRT8 DMD	3.08e-05	3	112	2	16000376
Pubmed	Human gut microbiota influences drug-metabolizing enzyme hepatic Cyp3a: A human flora-associated mice study.	CYP3A5 CYP3A43	3.08e-05	3	112	2	37258238
Pubmed	Effect of Naringenin, Quercetin, and Sesamin on Xenobiotica-Metabolizing CYP1A and CYP3A in Mice Offspring after Maternal Exposure to Persistent Organic Pollutants.	CYP3A5 CYP3A43	3.08e-05	3	112	2	28567424
Pubmed	A useful model capable of predicting the clearance of cytochrome 3A4 (CYP3A4) substrates in humans: validity of CYP3A4 transgenic mice lacking their own Cyp3a enzymes.	CYP3A5 CYP3A43	3.08e-05	3	112	2	25005602
Pubmed	Increased phosphorylation of ezrin/radixin/moesin proteins contributes to proliferation of rheumatoid fibroblast-like synoviocytes.	EZR RDX	3.08e-05	3	112	2	21278069
Pubmed	Cloning, sequencing, heterologous expression, and characterization of murine cytochrome P450 3a25*(Cyp3a25), a testosterone 6beta-hydroxylase.	CYP3A5 CYP3A43	3.08e-05	3	112	2	11284050
Pubmed	Collaborated regulation of female-specific murine Cyp3a41 gene expression by growth and glucocorticoid hormones.	CYP3A5 CYP3A43	3.08e-05	3	112	2	14733933
Pubmed	Genetic variations in androgen metabolism genes and associations with prostate cancer in South African men.	CYP3A5 CYP3A43	3.08e-05	3	112	2	21081028
Pubmed	Mouse cytochrome P450 (Cyp3a11): predominant expression in liver and capacity to activate aflatoxin B1.	CYP3A5 CYP3A43	3.08e-05	3	112	2	9143324
Pubmed	Isolation of a promoter region in mouse cytochrome P450 3A (Cyp3A16) gene and its transcriptional control.	CYP3A5 CYP3A43	3.08e-05	3	112	2	9048885
Pubmed	ARHGAP18: A Flow-Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis.	ARHGAP1 ARHGAP18	3.08e-05	3	112	2	30630384
Pubmed	Nuclear ERM (ezrin, radixin, moesin) proteins: regulation by cell density and nuclear import.	EZR RDX	3.08e-05	3	112	2	15149851
Pubmed	Lentiviral transgenic microRNA-based shRNA suppressed mouse cytochromosome P450 3A (CYP3A) expression in a dose-dependent and inheritable manner.	CYP3A5 CYP3A43	3.08e-05	3	112	2	22291988
Pubmed	CYP3A4, CYP3A5, and CYP3A43 genotypes and haplotypes in the etiology and severity of prostate cancer.	CYP3A5 CYP3A43	3.08e-05	3	112	2	15548719
Pubmed	ERM stable knockdown by siRNA reduced in vitro migration and invasion of human SGC-7901 cells.	EZR RDX	3.08e-05	3	112	2	21352885
Pubmed	CYP3A-mediated generation of aldehyde and hydrazine in atazanavir metabolism.	CYP3A5 CYP3A43	3.08e-05	3	112	2	21148252
Pubmed	A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites.	EZR RDX	3.08e-05	3	112	2	1429901
Pubmed	ERM Proteins at the Crossroad of Leukocyte Polarization, Migration and Intercellular Adhesion.	EZR RDX	3.08e-05	3	112	2	32098334
Pubmed	Different diets cause alterations in the enteric environment and trigger changes in the expression of hepatic cytochrome P450 3A, a drug-metabolizing enzyme.	CYP3A5 CYP3A43	3.08e-05	3	112	2	23370405
Pubmed	Ezrin, Radixin, and Moesin (ERM) proteins function as pleiotropic regulators of human immunodeficiency virus type 1 infection.	EZR RDX	3.08e-05	3	112	2	18295815
Pubmed	Dmoesin controls actin-based cell shape and polarity during Drosophila melanogaster oogenesis.	EZR RDX	3.08e-05	3	112	2	12360288
Pubmed	Selective inactivation of mouse liver cytochrome P-450IIIA by cannabidiol.	CYP3A5 CYP3A43	3.08e-05	3	112	2	2402224
Pubmed	Dynamics and function of ERM proteins during cytokinesis in human cells.	EZR RDX	3.08e-05	3	112	2	28889652
Pubmed	Control of adipogenesis by ezrin, radixin and moesin-dependent biomechanics remodeling.	EZR RDX	3.08e-05	3	112	2	23116763
Pubmed	Induction of ezrin-radixin-moesin molecules after cryogenic traumatic brain injury of the mouse cortex.	EZR RDX	3.08e-05	3	112	2	21451358
Pubmed	Genetic analysis of sensitization and tolerance to cocaine.	CYP3A5 CYP3A43	3.08e-05	3	112	2	7932176
Pubmed	Differential effects of ceramide and sphingosine 1-phosphate on ERM phosphorylation: probing sphingolipid signaling at the outer plasma membrane.	EZR RDX	3.08e-05	3	112	2	20679347
Pubmed	Divergent activities of osteogenic BMP2, and tenogenic BMP12 and BMP13 independent of receptor binding affinities.	GDF6 GDF7	3.08e-05	3	112	2	21702718
Pubmed	Differential expression and distribution of ezrin, radixin and moesin in human natural killer cells.	EZR RDX	3.08e-05	3	112	2	12385025
Pubmed	Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?	EZR RDX	3.08e-05	3	112	2	25286001
Pubmed	Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications.	EZR RDX	3.08e-05	3	112	2	17977945
Pubmed	Ezrin/radixin/moesin proteins are high affinity targets for ADP-ribosylation by Pseudomonas aeruginosa ExoS.	EZR RDX	3.08e-05	3	112	2	15252013
Pubmed	ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation.	EZR RDX	3.08e-05	3	112	2	32160548
Pubmed	The amino-terminal domains of the ezrin, radixin, and moesin (ERM) proteins bind advanced glycation end products, an interaction that may play a role in the development of diabetic complications.	EZR RDX	3.08e-05	3	112	2	12734202
Cytoband	7q21.1	CYP3A5 CYP3A43	1.64e-04	8	112	2	7q21.1
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	KIF1A TIAM2 AFAP1L2 GRK2 TIAM1 VAV3	1.57e-04	206	71	6	682
GeneFamily	Cytochrome P450 family 3	CYP3A5 CYP3A43	4.19e-04	8	71	2	1002
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	EZR RDX PTPN4	9.96e-04	50	71	3	1293
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	GMIP ARHGAP1 ARHGAP18	9.96e-04	50	71	3	721
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	TIAM2 TIAM1 VAV3	2.22e-03	66	71	3	722
Coexpression	GSE9601_UNTREATED_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP	EZR E2F7 NDUFS8 GRK2 PTPRS PRKCQ ZC3H7B	1.03e-05	176	111	7	M6882
Coexpression	BUSSLINGER_DUODENAL_LATE_IMMATURE_ENTEROCYTES	MGAM CYP2J2 CYP3A5 SI PTGR1 VNN1 HADHB	1.07e-05	177	111	7	M40028
Coexpression	GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_UP	RILPL1 VAV3 HADHB KDSR ZNF471 CNP MTMR9	2.36e-05	200	111	7	M5803
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#5_top-relative-expression-ranked_500	MGAM AGO2 PEG3 STMN2 PCDH20 CSPP1	5.91e-08	40	111	6	gudmap_developingGonad_e16.5_epididymis_500_k5
CoexpressionAtlas	dev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000	SOX5 PEG3 CCDC80 CHD3 PCDH20 LRIG2 PTPN4 PTGR1 PIK3C2A HECW2 VAV3 HADHB ARHGAP18 CSPP1 ZNF292	1.58e-05	791	111	15	gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#5_top-relative-expression-ranked_500	COL8A1 MAP4 STMN2 HHIP	2.00e-05	31	111	4	gudmap_developingLowerUrinaryTract_P1_bladder_J_500_k5
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	MGAM COL8A1 AGO2 MAP4 PEG3 STMN2 PCDH20 HHIP CEP295 CALCRL RNF145 CSPP1 ENPEP KNL1	7.28e-05	799	111	14	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	small intestine	MGAM KRT8 CYP2J2 CYP3A5 FLVCR1 SI VNN1 KCNK5 ENPEP	7.34e-05	339	111	9	small intestine
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_1000	SOX5 MGAM PRTG AGO2 PEG3 KIAA0586 STMN2 RDX PCDH20 HOXD3 CEP295 CALCRL RNF145 CSPP1	8.98e-05	815	111	14	gudmap_developingGonad_e11.5_ovary + mesonephros_1000
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#1_top-relative-expression-ranked_500	MGAM AGO2 PEG3 PCDH20 CSPP1	1.04e-04	89	111	5	gudmap_developingGonad_e11.5_ovary + mesonephros_k1_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#4_top-relative-expression-ranked_1000	PCDH20 HHIP HOOK3 PIK3C2A CALCRL ENPEP	1.43e-04	151	111	6	gudmap_developingLowerUrinaryTract_P1_ureter_1000_k4
ToppCell	ileum-Absorptive_Enterocytes\|ileum / shred on tissue and cell subclass	MGAM CYP3A5 SI PTGR1 ENPEP	6.09e-08	41	112	5	650cec538c6acd92f45d804b3c94248c6231aa21
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	FLNB STMN2 E2F7 PTPRS UHRF1 CALCRL KNL1	4.47e-07	185	112	7	9d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM CYP3A5 AOX1 ACSF2 KL KCNK5 ENPEP	4.63e-07	186	112	7	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM CYP3A5 AOX1 ACSF2 TENM1 KCNK5 ENPEP	4.80e-07	187	112	7	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM CYP3A5 AOX1 ACSF2 TENM1 KCNK5 ENPEP	4.80e-07	187	112	7	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	Fibroblasts-CD55+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	SOX5 EZR GDF5 FLNB HHIP TIAM1 SEMA3E	5.34e-07	190	112	7	b4088128f5acf53f43244c9af9fe44e033f1a57a
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCDC80 STOX1 KL AFAP1L2 VNN1 DMD ZNF471	5.34e-07	190	112	7	3cf464664d6aa22b212e60b70885953887e92483
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EZR FLNB CYP3A5 ACSF2 TIAM1 PTGR1 SEMA3E	5.94e-07	193	112	7	a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EZR DPP6 SLC26A9 HHIP PRKCQ RNF145 ALPL	6.15e-07	194	112	7	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	5'-Adult-SmallIntestine-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM KRT8 CYP3A5 SI PTGR1 VNN1 ENPEP	7.05e-07	198	112	7	8d629492d2199de8e036c19e9dacceb9c9e721a0
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM KRT8 CYP2J2 CYP3A5 SI PTGR1 ENPEP	7.05e-07	198	112	7	2967fb2d94662997bfe932ac299c80d6f182fb48
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM KRT8 CYP3A5 FLVCR1 SI PTGR1 ENPEP	7.05e-07	198	112	7	8fac96132663f54566136ef54b53684d31dfde32
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM KRT8 CYP2J2 CYP3A5 SI PTGR1 ENPEP	7.05e-07	198	112	7	222a060c2c63d30da34e4b71c37aa27a048d7d09
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM KRT8 CYP3A5 FLVCR1 SI PTGR1 ENPEP	7.05e-07	198	112	7	c48b3f026b16d48b8eca9f74dc1e3f3f39a89322
ToppCell	5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM KRT8 CYP3A5 SI PTGR1 VNN1 ENPEP	7.05e-07	198	112	7	6e6af8fad09f8e48b3f2ce463d5773b6a69864d1
ToppCell	5'-Adult-SmallIntestine-Epithelial-mature_enterocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM KRT8 CYP3A5 SI PTGR1 VNN1 ENPEP	7.29e-07	199	112	7	01c2721bc82cd672e9477029b4a7ecc77e2f1b00
ToppCell	C_02\|World / shred on cell type and cluster	MGAM FLNB CYP3A5 SI PTGR1 ENPEP	3.85e-06	165	112	6	a456c2c9ffe8dc91e17cac84ba87b88e016f8e6d
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPP6 FLNB COL8A1 STMN2 RDX CALCRL	5.58e-06	176	112	6	27e6b3ae41068d6cfdda3d46da7df2a27567140e
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPP6 FLNB COL8A1 STMN2 RDX CALCRL	5.58e-06	176	112	6	d6a5470af9592f34a741265f2ea9651c05c3add3
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	STOX1 HECW2 UHRF1 VAV3 CALCRL ARHGAP18	6.15e-06	179	112	6	d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX5 PEG3 TMEM132B TIAM2 PTPRS DMD	6.15e-06	179	112	6	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	(3)_Chondrocytes-(32)_Chondro-prehyper-2\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	OGT CCDC80 TMEM132B VNN1 KCNK5 VAV3	6.35e-06	180	112	6	708a5c89b9337e281fce4f482892a1c1766c7812
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|(2)_5-FU / Stress and Cell class	MYO1E PEG3 CCDC80 SH3PXD2B PTPRS ALPL	6.56e-06	181	112	6	56ae86072858c156681507aecd1bc6cb0a3372d2
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PEG3 CCDC80 TMEM132B HHIP PTPRS DMD	6.98e-06	183	112	6	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDF5 AOX1 STMN2 CCDC80 HECW2 SEMA3E	6.98e-06	183	112	6	f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|World / Stress and Cell class	MYO1E PEG3 CCDC80 SH3PXD2B PTPRS ALPL	7.20e-06	184	112	6	684d05340a3dfb8aa08b881516a37f9627a10448
ToppCell	IPF-Epithelial-ATII\|World / Disease state, Lineage and Cell class	SOX5 COL8A1 KRT8 SLC26A9 HHIP ALPL	7.66e-06	186	112	6	6a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB STMN2 STOX1 TIAM1 CALCRL KDSR	7.90e-06	187	112	6	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB STMN2 STOX1 TIAM1 CALCRL KDSR	7.90e-06	187	112	6	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	15-Distal-Epithelial-Secretory_progenitor\|Distal / Age, Tissue, Lineage and Cell class	KRT8 CYP2J2 PCDH20 DMD ALPL SEMA3E	8.14e-06	188	112	6	9a64fb07de611de38d6f24673feb3b81a5e85384
ToppCell	10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SOX5 GDF5 CCDC80 TENM1 CC2D2A SEMA3E	8.14e-06	188	112	6	0e2d1b21f0a7ee306e7dae16fc8c19d16a467883
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STMN2 AFAP1L2 HECW2 VAV3 CALCRL ALPL	8.65e-06	190	112	6	9d5242759546be0089981ef1877e4ed5f81face5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 COL8A1 CCDC80 HHIP PTPRS DMD	8.65e-06	190	112	6	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EZR E2F7 CCDC80 STOX1 CC2D2A IK	8.91e-06	191	112	6	683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	COL8A1 AOX1 CCDC80 SH3PXD2B PTPRS CALCRL	9.18e-06	192	112	6	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	SOX5 DPP6 PRTG SLC26A9 HHIP ALPL	9.18e-06	192	112	6	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPP6 NYAP2 KIF1A STMN2 HOXD3 CLVS2	9.18e-06	192	112	6	2f1c4ef693515ccc7231bd8c6641fad51d445d20
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	COL8A1 AOX1 CCDC80 SH3PXD2B PTPRS CALCRL	9.46e-06	193	112	6	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM KRT8 CYP3A5 SI PTGR1 ENPEP	9.74e-06	194	112	6	2f6e62a4ec8707bd5a16c0734c5131af55207ea2
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT8 CYP3A5 SI TIAM2 VNN1 ENPEP	1.00e-05	195	112	6	e87b11e3242fdbed2e7f383e6876ec375af32bd4
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated-diff\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EZR KRT8 FHAD1 CC2D2A ARHGAP18 IK	1.06e-05	197	112	6	32484fb5dde0a4525dd8028dde01ca5a4e51e4b6
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX5 GDF5 COL8A1 PEG3 CCDC80 TIAM2	1.06e-05	197	112	6	6e111ba16fc8adde782b3f7da250248cddf11228
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EZR CCDC80 STOX1 FHAD1 CC2D2A IK	1.06e-05	197	112	6	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	OGT CHD3 FRYL TENM1 PRKCQ ZNF292	1.06e-05	197	112	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated-diff\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EZR KRT8 CCDC80 CC2D2A ARHGAP18 IK	1.06e-05	197	112	6	009dc732c43bfdc0d5a662b2c7d1a7a86b0d1d24
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPP6 NYAP2 KIF1A STMN2 HOXD3 CLVS2	1.06e-05	197	112	6	a1ae1aa797762a3768e14434c7e5cd19c595ecb3
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX5 GDF5 COL8A1 PEG3 CCDC80 TIAM2	1.06e-05	197	112	6	4b6c0e028b9669c102df8e9dc63e284f8d5fd9ee
ToppCell	AT2_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	EZR COL8A1 KRT8 CHD3 HHIP ALPL	1.06e-05	197	112	6	42e49a8ce3118db6c2fd620d70c480b75143c828
ToppCell	critical-Epithelial-Ciliated-diff\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	EZR KRT8 CCDC80 FHAD1 ARHGAP18 IK	1.06e-05	197	112	6	34fa5568eb5e5f1ee5d4c7e5d237997eaca573ae
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX5 GDF5 COL8A1 PEG3 CCDC80 TIAM2	1.06e-05	197	112	6	ece0c17eb68f394b20e588c0b0626d3987a4dbbb
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPP6 NYAP2 KIF1A STMN2 HOXD3 CLVS2	1.06e-05	197	112	6	5593721407f61fc5bc3f2f8bf8fa2604c4e29565
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM KRT8 CYP3A5 SI PTGR1 ENPEP	1.09e-05	198	112	6	e3e2233c796d5e9051c8c1b66f70f406f048ed56
ToppCell	Epithelial_cells-Epithelial_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	KRT8 AOX1 KL PTGR1 ENPEP ALPL	1.09e-05	198	112	6	52e9d41a1726bc1140df6baec9f17a534448ac8b
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DPP6 PRTG SLC26A9 HHIP RNF145 ALPL	1.09e-05	198	112	6	2e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell	facs-Trachea-nan-3m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX5 GDF5 COL8A1 PEG3 CCDC80 TIAM2	1.09e-05	198	112	6	71e847e8c24744d6df4a960348ad2ecf310373b4
ToppCell	Epithelial_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	KRT8 AOX1 KL PTGR1 ENPEP ALPL	1.09e-05	198	112	6	eeec789d226171f30799577cc37c07bdced2e3cb
ToppCell	3'-Child09-12-SmallIntestine-Epithelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM KRT8 CYP3A5 SI PTGR1 ENPEP	1.13e-05	199	112	6	043c65bdf54a1bf0e483fea9ffc042ff5b271764
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX5 COL8A1 KIF1A TIAM1 KCNK5 CNP	1.13e-05	199	112	6	ce699726ac4825c65bf934cb9a76202ad7340596
ToppCell	5'-Adult-SmallIntestine\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM CYP3A5 SI PTGR1 VNN1 ENPEP	1.13e-05	199	112	6	a5fffe381be1ba7d192b68d1d3937ce47663658e
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX5 COL8A1 KIF1A TIAM1 KCNK5 CNP	1.13e-05	199	112	6	f1d5808ccb1d5d4e2d34f864e705e2484000e88f
ToppCell	3'-Child04-06-SmallIntestine-Epithelial\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM KRT8 CYP3A5 SI PTGR1 ENPEP	1.13e-05	199	112	6	ab71b312635a2b2c98d71b60a299f44bc80a3587
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	SOX5 NYAP2 STMN2 CHD3 EIF3L SEMA3E	1.13e-05	199	112	6	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM KRT8 CYP3A5 SI PTGR1 ENPEP	1.13e-05	199	112	6	0181c13379f869be47804cdb11bbdabcd30b9b23
ToppCell	Biopsy_Control_(H.)-Epithelial-AT2\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	PRTG KRT8 SLC26A9 HHIP RNF145 ALPL	1.13e-05	199	112	6	5323d49d3be980605b3e609b7f03bddba6e50e8a
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	SOX5 NYAP2 STMN2 CHD3 EIF3L SEMA3E	1.13e-05	199	112	6	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-mature_enterocytic\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM KRT8 CYP3A5 SI PTGR1 ENPEP	1.13e-05	199	112	6	ee981046217e8759610eb58a670d98f32cd83abc
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-CD141-positive_myeloid_dendritic_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LPAR3 TIAM1 CALCRL ANO3 MTMR9	2.26e-05	134	112	5	0b1bb6fee8a2d8c27bca6d9cac6b47e85073dbf7
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PRTG ABCA12 ANO3 ALPL SEMA3E	3.76e-05	149	112	5	c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PRTG ABCA12 ANO3 ALPL SEMA3E	3.76e-05	149	112	5	a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 LPAR3 DMD ANO3 SEMA3E	4.13e-05	152	112	5	bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 LPAR3 DMD ANO3 SEMA3E	4.13e-05	152	112	5	ee329249a034a969a16b26a224aa04249d67382d
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX5 PKDREJ AFAP1L2 CALCRL SEMA3E	4.53e-05	155	112	5	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	18-Distal-Epithelial-Basal_cell\|Distal / Age, Tissue, Lineage and Cell class	CYP2J2 PCDH20 KL CEP295 ALPL	4.97e-05	158	112	5	183f445967e09e871c93d8e94781ed9fec894169
ToppCell	(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts\|World / Stress and Cell class	MYO1E PEG3 CCDC80 PTPRS ALPL	5.27e-05	160	112	5	ab769516f9f7798d1390ef215caf22a2d3d53e63
ToppCell	(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts\|(1)_Control_(PBS) / Stress and Cell class	PEG3 CCDC80 PTPRS ATIC ALPL	5.27e-05	160	112	5	8450466fc2465c56798df2b520edd23c2c2e941c
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Fibroblasts-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PEG3 CCDC80 STOX1 KCNK5 ANO3	5.27e-05	160	112	5	778faada072e3abfa76a9a06fd4885fb63de7902
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX5 KRT8 FHAD1 ATIC ALPL	5.43e-05	161	112	5	249c2b97cc25de5053f5048ee354615df49b2081
ToppCell	Severe-Lymphoid-NK-CCR7+_T\|Severe / Condition, Lineage, Cell class and cell subclass	ZNF343 CAGE1 RILPL1 AFAP1L2 PRKCQ	5.76e-05	163	112	5	8f0d8c124f1569a5a6bc1db7581989f24d63cca3
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX5 COL8A1 PRTG PEG3 CCDC80	6.28e-05	166	112	5	37794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX5 COL8A1 PRTG PEG3 CCDC80	6.28e-05	166	112	5	81c546c6d847e49e662b81e71992ca0f7a99e890
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF1A E2F7 MYO3A UHRF1 KNL1	6.65e-05	168	112	5	d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	KIF1A TMEM132B AFAP1L2 HOXD3 CLVS2	6.83e-05	169	112	5	d9c3b22f62b882b8a2ea6fd9cf7afbe6d1775745
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SOX5 COL8A1 PEG3 CAGE1 ALPL	6.83e-05	169	112	5	58e22f9119240664515fe91ca53812611a8f17d6
ToppCell	ileum\|World / shred on tissue and cell subclass	MGAM CYP3A5 SI PTGR1 ENPEP	7.03e-05	170	112	5	9f1211bd4287620e19a59f21e6ecdca3e42e0260
ToppCell	MS-CD8-proli_CD4\|MS / Condition, Cell_class and T cell subcluster	FLNB GMIP TMEM132B TIAM2 CC2D2A	7.43e-05	172	112	5	0b6dd257110b3f17fa71ab18a165b091a9d5ae9a
ToppCell	(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts\|(0)_Normal/No_Treatment / Stress and Cell class	MYO1E CCDC80 SH3PXD2B PTPRS ALPL	7.63e-05	173	112	5	c2a0f674681836b5a868c13f67caa7d555ef6519
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX5 EZR MYO1E KCNK5 CNP	7.84e-05	174	112	5	28ec25767bbd4fd898738f9f4d2b585dc91b5adf
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LPAR3 E2F7 UHRF1 ATIC ARHGAP18	7.84e-05	174	112	5	09b091e24317c3f7bac043f04762a533e30793de
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPP6 COL8A1 KIF1A KL PLXNA1	8.06e-05	175	112	5	8362a46f5804333baa84cd56d450bc147f372a7e
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPP6 COL8A1 KIF1A KL PLXNA1	8.06e-05	175	112	5	8b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 STMN2 CCDC80 TENM1 ANO3	8.06e-05	175	112	5	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	droplet-Kidney-nan-18m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STMN2 E2F7 CCDC80 HECW2 CALCRL	8.28e-05	176	112	5	5386386619cf173939d3c117b20e6f27ab397993
ToppCell	wk_20-22-Epithelial-PNS-Late_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CYP2J2 TMEM132B AFAP1L2 ANO3 CNP	8.28e-05	176	112	5	81924471d8a8c5bd8eedf294c007e25b6cd3e417
ToppCell	Control-Lymphoid-pDC\|Control / Condition, Lineage and Cell class	FLNB STOX1 PTPRS CALCRL DMD	8.28e-05	176	112	5	5de16ff65476bde8b23322a44e11412e14f1bafe
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM AOX1 SLC26A9 ACSF2 ENPEP	8.28e-05	176	112	5	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	droplet-Kidney-nan-18m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STMN2 E2F7 CCDC80 HECW2 CALCRL	8.28e-05	176	112	5	820edade963768e4bfd86b554da4cd7100567ac8
ToppCell	facs-Brain_Myeloid-Striatum-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EZR FLVCR1 PTPN4 ZC3H7B PLXNA1	8.50e-05	177	112	5	f6b9d91d46830d0d207b0abd4ee5a4942fd99774
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PEG3 E2F7 NT5C1B UHRF1 KNL1	8.50e-05	177	112	5	8a74f5e72de605774111057bd87a7e7e4a6385cd
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANKRD62 KL TENM1 CALCRL SEMA3E	8.50e-05	177	112	5	bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCell	tumor_Lung-Endothelial_cells-EPCs\|tumor_Lung / Location, Cell class and cell subclass	PCDHA10 PGAP4 KL HECW2 CALCRL	8.50e-05	177	112	5	f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
Drug	AC1L53LJ	MGAM KRT8 SI	1.09e-06	5	110	3	CID000197521
Drug	isomaltotetraose	MGAM KRT8 SI	3.79e-06	7	110	3	CID003080783
Drug	hydroxyl radicals	MGAM CYP2J2 CYP3A5 USP28 CYP3A43 AOX1 SLC26A9 RDX SI NT5C1B PTPN4 SAG PTPRS VNN1 PRKCQ ATIC HADHB CALCRL CNP ALPL	5.95e-06	1341	110	20	CID000000961
Drug	methyldiazonium ion	MGAM CYP3A5 PTPN4	6.04e-06	8	110	3	CID000115287
Disease	Joubert syndrome with Jeune asphyxiating thoracic dystrophy	KIAA0586 CSPP1	1.35e-05	2	109	2	C4518774
Disease	cataract 48 (implicated_via_orthology)	TIAM2 TIAM1	1.35e-05	2	109	2	DOID:0070354 (implicated_via_orthology)
Disease	femoral neck size	GDF5 HHIP	4.05e-05	3	109	2	EFO_0010076
Disease	Multiple synostosis syndrome	GDF5 GDF6	8.07e-05	4	109	2	cv:C0175700
Disease	Prostatic Neoplasms	EZR ATR CYP3A5 USP28 CYP3A43 AOX1 CHD3 HOXD3 VAV3 ZNF292	9.78e-05	616	109	10	C0033578
Disease	Malignant neoplasm of prostate	EZR ATR CYP3A5 USP28 CYP3A43 AOX1 CHD3 HOXD3 VAV3 ZNF292	9.78e-05	616	109	10	C0376358
Disease	pelvic organ prolapse	SOX5 DPP6 FHAD1 GDF7 HOXD3	1.54e-04	136	109	5	EFO_0004710
Disease	1,5 anhydroglucitol measurement	MGAM PCDHA10 SI	1.67e-04	29	109	3	EFO_0008009
Disease	brain disease (implicated_via_orthology)	TIAM2 TIAM1	2.01e-04	6	109	2	DOID:936 (implicated_via_orthology)
Disease	nephrolithiasis	SAG KCNK5 ALPL	2.47e-04	33	109	3	EFO_0004253
Disease	joint hypermobility measurement	GDF5 PRTG CC2D2A	2.47e-04	33	109	3	EFO_0007905
Disease	Colorectal Carcinoma	ABCA12 PEG3 HHIP KL TIAM1 PTPRS TENM1 DMD ZNF471 ZNF292	2.80e-04	702	109	10	C0009402
Disease	anxiety, vitamin D measurement	DPP6 SEMA3E	2.81e-04	7	109	2	EFO_0004631, EFO_0005230
Disease	prostate carcinoma	GDF5 PRTG KRT8 USP28 CHD3 SH3PXD2B GDF7 CLVS2 KDSR MTMR9 KNL1	4.66e-04	891	109	11	EFO_0001663
Disease	Tumoral calcinosis	KL DMD ALPL	5.07e-04	42	109	3	C0263628
Disease	Calcinosis	KL DMD ALPL	5.07e-04	42	109	3	C0006663
Disease	Microcalcification	KL DMD ALPL	5.07e-04	42	109	3	C0521174
Disease	response to carboplatin, response to antineoplastic agent	FLNB PRTG	5.97e-04	10	109	2	GO_0097327, GO_0097328
Disease	Gastrointestinal Stromal Sarcoma	HHIP CC2D2A DMD	7.06e-04	47	109	3	C3179349
Disease	Congenital Abnormality	COL8A1 GRK2	7.28e-04	11	109	2	C0000768
Disease	alpha angle measurement	SOX5 TIAM2	7.28e-04	11	109	2	EFO_0020071
Disease	Gastrointestinal Stromal Tumors	HHIP CC2D2A DMD	8.47e-04	50	109	3	C0238198
Disease	cleft palate (is_implicated_in)	FLNB GDF6	8.71e-04	12	109	2	DOID:674 (is_implicated_in)
Disease	Polydactyly	GDF5 KIAA0586 CC2D2A CSPP1	9.48e-04	117	109	4	C0152427
Disease	5-methyluridine (ribothymidine) measurement	PTPRS SEMA3E	1.20e-03	14	109	2	EFO_0020013
Disease	prostate carcinoma, type 2 diabetes mellitus	NYAP2 GDF7 KNL1	1.37e-03	59	109	3	EFO_0001663, MONDO_0005148
Disease	Meckel-Gruber syndrome	CC2D2A CSPP1	1.38e-03	15	109	2	C0265215
Disease	glycerol-3-phosphate measurement	COL8A1 ALPL	1.38e-03	15	109	2	EFO_0010488
Disease	level of Phosphatidylethanolamine (16:0_20:4) in blood serum	NYAP2 MYO1E	1.57e-03	16	109	2	OBA_2045137
Disease	thyroxine measurement, triiodothyronine measurement	CCDC80 TIAM2	1.77e-03	17	109	2	EFO_0005130, EFO_0008392
Disease	Meckel syndrome type 1	CC2D2A CSPP1	1.99e-03	18	109	2	C3714506
Disease	metabolonic lactone sulfate measurement	CYP3A5 CYP3A43	2.22e-03	19	109	2	EFO_0800659
Disease	gait measurement	GDF5 NYAP2 UHRF1 ANO3	2.36e-03	150	109	4	EFO_0007680
Disease	electroencephalogram measurement	E2F7 MYO3A DMD	2.63e-03	74	109	3	EFO_0004357
Disease	body surface area	SOX5 GDF5 KIF1A E2F7 TIAM2 HHIP KCNK5 UHRF1	2.69e-03	643	109	8	EFO_0022196
Disease	Joubert syndrome 1	KIAA0586 CSPP1	2.71e-03	21	109	2	C4551568
Disease	Disproportionate short stature	GDF5 FLNB SH3PXD2B	2.94e-03	77	109	3	C0878659
Disease	Primary microcephaly	DPP6 KNL1	2.98e-03	22	109	2	C0431350
Disease	infant body height	GDF5 HHIP	3.25e-03	23	109	2	EFO_0006785

Protein segments in the cluster

Peptide	Gene	Start	Entry
GLEKYMEYQLTNENV	NT5C1B	331	Q96P26
EMTEKPEFQSQVYNY	CAGE1	136	Q8TC20
YMALYPEIQEKVQAE	CYP2J2	326	P51589
NKAPPTYDAVVQMEY	CYP3A5	341	P20815
AYGVEYPNETFEMNK	ABCA12	2171	Q86UK0
DEEYIYMNKVTINKQ	AFAP1L2	51	Q8N4X5
IEHMYQNDQPILEKY	ANKRD62	751	A6NC57
LVSVNPAYQAMELEY	ACSF2	151	Q96CM8
SDYYVKPVAMEEAQE	SAG	256	P10523
YIADKVDAAQMPQEA	DMD	1396	P11532
YLRDFMYVSQDPKDQ	HADHB	336	P55084
QANFFEMDIPKIDIY	AGO2	41	Q9UKV8
PKAENNMYVQQRDEY	CCDC80	631	Q76M96
YMAPEVLQKGVAYDS	GRK2	356	P25098
QFEAKYYKMEIVNPI	ANO3	516	Q9BYT9
DQEMDVYVSTQFPKY	AOX1	766	Q06278
NEDYINANYINMEIP	PTPN4	701	P29074
AEAESMYQIKYEELQ	KRT8	276	P05787
QDLEMYGVNYFEIKN	RDX	196	P35241
PQYQDMVPVAYNDKI	HECW2	1071	Q9P2P5
TTKPMDYELQQFYEV	PCDH20	491	Q8N6Y1
VLVKEYVESENGQMY	PRKCQ	31	Q04759
SANNVVYKQYEDMVV	GDF5	481	P43026
TEFLEEKMAYQEYPN	MAP4	101	P27816
AYEEMVNIIEYNKEL	MTMR9	511	Q96QG7
AMETVAQQKRDYYQP	GMIP	166	Q9P107
MQKGDPQVYEELFSY	EIF3L	401	Q9Y262
SLYDEMVAAQIPYDV	MGAM	1261	O43451
MVAAQIPYDVQYSDI	MGAM	1266	O43451
EMVAAQIPYDVQYSD	MGAM	2161	O43451
SQEGPYMVSVKYADE	FLNB	1486	O75369
YYADIAKMPAISDQD	PLXNA1	1816	Q9UIW2
ESELSVPYEQLMNEY	KCNK5	476	O95279
QVYNKQDYDLMVFPE	PIK3C2A	66	O00443
EYEAKLEAEMRTYNP	CSPP1	656	Q1MSJ5
DEEAKVIGMSVYYPQ	FRYL	496	O94915
SVVNPIIYSYKDEDM	LPAR3	286	Q9UBY5
ETYQKEISPYENKMG	KNL1	1766	Q8NG31
ELYPMIEEYFQGQVK	ENPEP	711	Q07075
TYNPDYVLMVEDDAV	PGAP4	201	Q9BRR3
ELPECTMQKAAYYEN	HOXD3	11	P31249
DDQSEAVYEEMKYPI	NYAP2	261	Q9P242
MAQVLQKIDPAYFDE	HOOK3	41	Q86VS8
LENYKEMYQPEDDNN	PEG3	121	Q9GZU2
AVAATYKYVNMQDPE	NDUFS8	31	O00217
EYEMVITNLQPETAY	PTPRS	791	Q13332
FDRPVYEVKMYENQV	PCDHA10	241	Q9Y5I2
YMKAEGLNNEEYQVV	PRTG	456	Q2VWP7
MYPKNKTDVEYESDE	ALPL	226	P05186
EVYAAVMNPINEYKD	COG6	626	Q9Y2V7
EAEAYRNIEPVYLNM	ATR	306	Q13535
EMYQSQVAKLEDDIY	FHAD1	1326	B1AJZ9
NYKQVPVYDREIMEK	CC2D2A	926	Q9P2K1
PVYDREIMEKVFQDY	CC2D2A	931	Q9P2K1
GEEQKYEEQMAYLQQ	E2F7	226	Q96AV8
NKAPVTYDALVQMEY	CYP3A43	341	Q9HB55
DEMNIPEYEEHKQSY	CHD3	666	Q12873
EMADQYQYQVVLVEP	CNP	136	P09543
VALFKNNEPVMYTYD	COL8A1	676	P27658
NQMILTYYEGEEVNA	FLVCR1	356	Q9Y5Y0
KNYNVPYEPDSVVMA	IST1	171	P53990
PIKYNDYLEVQEMTD	KL	821	Q9UEF7
QDLEMYGINYFEIKN	EZR	196	P15311
MPKVEYRDIEIDDYN	DPP6	591	P42658
QLDAQREVMYSYEKP	CEP295	1606	Q9C0D2
LAEALQMEVKPYNVY	KDSR	196	Q06136
YECYQKIMQDPIQQA	CALCRL	46	Q16602
NAYVEKYGAKMEAPQ	C18orf63	81	Q68DL7
KQMDSRYYPEVNEEE	KIF1A	676	Q12756
AEVAEQYSEKLAYMP	OGT	686	O15294
IQYKEYIIEGFENMP	PTGR1	296	Q14914
GNNVVYKQYEDMVVE	GDF6	436	Q6KF10
MQELENYSEGDPLYK	RGPD4	751	Q7Z3J3
SDYVYEKEIKNEPMN	TMEM132B	1001	Q14DG7
AQVMDTDIYVNPKTY	SLC26A9	506	Q7LBE3
EYEAYLPMAENEVRK	MOCS2	91	O96007
ILSAYEEMKQPVYEE	PKDREJ	2171	Q9NTG1
ANNVVYKQYEDMVVE	GDF7	431	Q7Z4P5
KYNMGLPVDFDQYNE	ARHGAP1	296	Q07960
MNIYEIASPADQELY	TENM1	1531	Q9UKZ4
ELYDAMVAANIPYDV	SI	1241	P14410
MVAANIPYDVQYTDI	SI	1246	P14410
EYLEQMETPQKEAYL	IQANK1	91	A8MXQ7
KAMARDEKNYYQDTP	NOP16	131	Q9Y3C1
PASNYLDQMEEYDKV	HHIP	191	Q96QV1
YNVDSYSMPVKEVEK	CLVS2	276	Q5SYC1
PEQRNLYKEVMLENY	ZNF343	81	Q6P1L6
KAVNEYDETMEKYIP	TTC30B	411	Q8N4P2
SYKMSENIPNEVYAL	VNN1	366	O95497
KMQLYVPQPEEDIYE	TIAM1	816	Q13009
EYMQQQVYDEIEVFP	TIAM2	871	Q8IVF5
AYYKSEEMEEENRIP	RILPL1	321	Q5EBL4
YAEQPNDKMEAESIY	STOX1	551	Q6ZVD7
PMVLEQYVVVANYQK	SH3PXD2B	151	A1X283
VEMLYNQPDQKYDEE	ZNF292	406	O60281
QEEYSEYMNNKEALP	IK	486	Q13123
MYINDKLPYFNAEAA	USP28	646	Q96RU2
NYCVLQMDQSYKPDE	ATIC	361	P31939
VQSFPLDEQMYAKYV	SUCO	406	Q9UBS9
YYSMNVEVTDKGDVP	TRBV27	66	A0A0K0K1C4
EGYINQKIISYEEMP	ZNF780B	136	Q9Y6R6
DTYMKDLYQLNPNAE	ARHGAP18	641	Q8N392
VKYDDYPENGVVQMN	UHRF1	186	Q96T88
YVTQELPLKQFMYDD	ZNF471	91	Q9BX82
FMQVEKPYESYIGAN	VPS26A	111	O75436
KAVNEYDETMEKYIP	TTC30A	411	Q86WT1
YMIPDNEDRDDNKVY	SEMA3E	231	O15041
NINIYTYDDMEVKQI	STMN2	31	Q93045
AMTNLEKQPYYEEQA	SOX5	596	P35711
KALYNDVMQENYETV	ZNF75A	16	Q96N20
KEPVENMDDVIYYVN	RNF145	441	Q96MT1
DEMYNPEFFYENVKI	SNRNP48	91	Q6IEG0
VIQDEDYMLQVYGKP	KIAA0586	621	Q9BVV6
DYKQALVQYMEGLNV	ZC3H7B	51	Q9UGR2
GDNYEMKEIIDLQQY	VAV3	436	Q9UKW4
EVKMNYNELTEIPYF	LRIG2	101	O94898
KEIEMYQGAAQYENP	MYO1E	71	Q12965
YQTPKKMNNVYEEEV	MYO3A	1186	Q8NEV4
KMNNVYEEEVKQEFY	MYO3A	1191	Q8NEV4