Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K4me/H3K4me2/H3K4me3 demethylase activity	KDM5A KDM5C KDM5D	9.30e-07	6	73	3	GO:0034647
GeneOntologyMolecularFunction	histone H3K4 demethylase activity	KDM5A KDM5C KDM5D	2.59e-06	8	73	3	GO:0032453
GeneOntologyMolecularFunction	peptidase activity	MEP1B ADAMTS10 ADAMTS19 CD5L ADAMTS6 USP32 LTF TMPRSS7 GGT1 GGT3P	1.28e-04	654	73	10	GO:0008233
GeneOntologyMolecularFunction	histone H3 demethylase activity	KDM5A KDM5C KDM5D	1.44e-04	28	73	3	GO:0141052
GeneOntologyMolecularFunction	histone modifying activity	HDAC4 ATR KDM5A NSD2 KDM5C KDM5D	1.91e-04	229	73	6	GO:0140993
GeneOntologyMolecularFunction	histone demethylase activity	KDM5A KDM5C KDM5D	1.96e-04	31	73	3	GO:0032452
GeneOntologyMolecularFunction	peptidyltransferase activity	GGT1 GGT3P	1.96e-04	6	73	2	GO:0000048
GeneOntologyMolecularFunction	leukotriene-C(4) hydrolase	GGT1 GGT3P	1.96e-04	6	73	2	GO:0002951
GeneOntologyMolecularFunction	protein demethylase activity	KDM5A KDM5C KDM5D	2.15e-04	32	73	3	GO:0140457
GeneOntologyMolecularFunction	transition metal ion binding	MEP1B GPC1 TRIM16 HDAC4 KDM5A KDM5C TUT7 POLR2L PPM1M GCM1 LTF SKI ZNF331	3.38e-04	1189	73	13	GO:0046914
GeneOntologyMolecularFunction	leukotriene C4 gamma-glutamyl transferase activity	GGT1 GGT3P	3.64e-04	8	73	2	GO:0103068
GeneOntologyMolecularFunction	glutathione hydrolase activity	GGT1 GGT3P	4.67e-04	9	73	2	GO:0036374
GeneOntologyMolecularFunction	demethylase activity	KDM5A KDM5C KDM5D	5.57e-04	44	73	3	GO:0032451
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL4A2 MATN2 LAMC1 PRG4 FGL2	6.28e-04	188	73	5	GO:0005201
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	MARS1 TUT7 POLR2L DUS3L EXOSC7 GGT1 GGT3P	8.20e-04	417	73	7	GO:0140098
GeneOntologyMolecularFunction	endopeptidase activity	MEP1B ADAMTS10 ADAMTS19 CD5L ADAMTS6 LTF TMPRSS7	9.81e-04	430	73	7	GO:0004175
GeneOntologyMolecularFunction	metalloendopeptidase activity	MEP1B ADAMTS10 ADAMTS19 ADAMTS6	9.81e-04	120	73	4	GO:0004222
GeneOntologyMolecularFunction	zinc ion binding	MEP1B TRIM16 HDAC4 KDM5A KDM5C TUT7 POLR2L GCM1 SKI ZNF331	1.44e-03	891	73	10	GO:0008270
GeneOntologyMolecularFunction	omega peptidase activity	GGT1 GGT3P	1.53e-03	16	73	2	GO:0008242
GeneOntologyMolecularFunction	2-oxoglutarate-dependent dioxygenase activity	KDM5A KDM5C KDM5D	1.74e-03	65	73	3	GO:0016706
GeneOntologyMolecularFunction	catalytic activity, acting on a tRNA	MARS1 DUS3L GGT1 GGT3P	1.92e-03	144	73	4	GO:0140101
GeneOntologyMolecularFunction	adenylate cyclase activity	ADCY1 ADCY9	1.94e-03	18	73	2	GO:0004016
GeneOntologyMolecularFunction	threonine-type peptidase activity	GGT1 GGT3P	2.40e-03	20	73	2	GO:0070003
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	MARS1 TUT7 POLR2L DUS3L EXOSC7 GGT1 GGT3P DNMT3B	2.40e-03	645	73	8	GO:0140640
GeneOntologyMolecularFunction	cyclase activity	ADCY1 ADCY9	3.45e-03	24	73	2	GO:0009975
GeneOntologyMolecularFunction	phosphorus-oxygen lyase activity	ADCY1 ADCY9	3.75e-03	25	73	2	GO:0016849
Domain	Lys_sp_deMease-like_dom	KDM5A KDM5C KDM5D	2.29e-07	4	73	3	IPR013637
Domain	PLU-1	KDM5A KDM5C KDM5D	2.29e-07	4	73	3	PF08429
Domain	PHD	SP140L KDM5A BAZ2A NSD2 KDM5C KDM5D	4.71e-07	75	73	6	PF00628
Domain	zf-C5HC2	KDM5A KDM5C KDM5D	5.70e-07	5	73	3	PF02928
Domain	Znf_C5HC2	KDM5A KDM5C KDM5D	5.70e-07	5	73	3	IPR004198
Domain	Znf_PHD-finger	SP140L KDM5A BAZ2A NSD2 KDM5C KDM5D	6.42e-07	79	73	6	IPR019787
Domain	PHD	SP140L KDM5A BAZ2A NSD2 KDM5C KDM5D	1.30e-06	89	73	6	SM00249
Domain	Znf_PHD	SP140L KDM5A BAZ2A NSD2 KDM5C KDM5D	1.48e-06	91	73	6	IPR001965
Domain	Znf_FYVE_PHD	SP140L KDM5A BAZ2A NSD2 KDM5C KDM5D DNMT3B	1.71e-06	147	73	7	IPR011011
Domain	ZF_PHD_2	SP140L KDM5A BAZ2A NSD2 KDM5C KDM5D	1.91e-06	95	73	6	PS50016
Domain	ZF_PHD_1	SP140L KDM5A BAZ2A NSD2 KDM5C KDM5D	2.03e-06	96	73	6	PS01359
Domain	Zinc_finger_PHD-type_CS	SP140L KDM5A NSD2 KDM5C KDM5D	5.46e-06	65	73	5	IPR019786
Domain	JmjN	KDM5A KDM5C KDM5D	6.74e-06	10	73	3	SM00545
Domain	JMJN	KDM5A KDM5C KDM5D	6.74e-06	10	73	3	PS51183
Domain	JmjN	KDM5A KDM5C KDM5D	6.74e-06	10	73	3	PF02375
Domain	JmjN	KDM5A KDM5C KDM5D	6.74e-06	10	73	3	IPR003349
Domain	PLAC	ADAMTS10 ADAMTS19 ADAMTS6	2.02e-05	14	73	3	PF08686
Domain	-	KDM5A KDM5C KDM5D	2.52e-05	15	73	3	1.10.150.60
Domain	BRIGHT	KDM5A KDM5C KDM5D	2.52e-05	15	73	3	SM00501
Domain	ARID_dom	KDM5A KDM5C KDM5D	2.52e-05	15	73	3	IPR001606
Domain	ARID	KDM5A KDM5C KDM5D	2.52e-05	15	73	3	PS51011
Domain	ARID	KDM5A KDM5C KDM5D	2.52e-05	15	73	3	PF01388
Domain	CCDC85	CCDC85C CCDC85A	4.51e-05	3	73	2	IPR019359
Domain	CCDC85	CCDC85C CCDC85A	4.51e-05	3	73	2	PF10226
Domain	PLAC	ADAMTS10 ADAMTS19 ADAMTS6	5.31e-05	19	73	3	PS50900
Domain	PLAC	ADAMTS10 ADAMTS19 ADAMTS6	5.31e-05	19	73	3	IPR010909
Domain	ADAM_spacer1	ADAMTS10 ADAMTS19 ADAMTS6	9.59e-05	23	73	3	IPR010294
Domain	ADAM_spacer1	ADAMTS10 ADAMTS19 ADAMTS6	9.59e-05	23	73	3	PF05986
Domain	TSP_1	ADAMTS10 ADAMTS19 ADAMTS6 THSD7B	1.07e-04	63	73	4	PF00090
Domain	JmjC	KDM5A KDM5C KDM5D	1.09e-04	24	73	3	PF02373
Domain	Peptidase_M12B_ADAM-TS	ADAMTS10 ADAMTS19 ADAMTS6	1.09e-04	24	73	3	IPR013273
Domain	TSP1	ADAMTS10 ADAMTS19 ADAMTS6 THSD7B	1.21e-04	65	73	4	SM00209
Domain	TSP1_rpt	ADAMTS10 ADAMTS19 ADAMTS6 THSD7B	1.21e-04	65	73	4	IPR000884
Domain	TSP1	ADAMTS10 ADAMTS19 ADAMTS6 THSD7B	1.21e-04	65	73	4	PS50092
Domain	JMJC	KDM5A KDM5C KDM5D	2.62e-04	32	73	3	PS51184
Domain	JmjC_dom	KDM5A KDM5C KDM5D	2.62e-04	32	73	3	IPR003347
Domain	MetalloPept_cat_dom	MEP1B ADAMTS10 ADAMTS19 ADAMTS6	2.85e-04	81	73	4	IPR024079
Domain	-	MEP1B ADAMTS10 ADAMTS19 ADAMTS6	2.85e-04	81	73	4	3.40.390.10
Domain	JmjC	KDM5A KDM5C KDM5D	2.87e-04	33	73	3	SM00558
Domain	GGT_peptidase	GGT1 GGT3P	3.12e-04	7	73	2	IPR000101
Domain	G_GLU_TRANSPEPTIDASE	GGT1 GGT3P	3.12e-04	7	73	2	PS00462
Domain	G_glu_transpept	GGT1 GGT3P	3.12e-04	7	73	2	PF01019
Domain	Peptidase_M12B_N	ADAMTS10 ADAMTS19 ADAMTS6	4.73e-04	39	73	3	IPR002870
Domain	Pep_M12B_propep	ADAMTS10 ADAMTS19 ADAMTS6	4.73e-04	39	73	3	PF01562
Domain	-	VLDLR ELP1 HHIPL1	4.73e-04	39	73	3	2.120.10.30
Domain	DISINTEGRIN_1	ADAMTS10 ADAMTS19 ADAMTS6	5.10e-04	40	73	3	PS00427
Domain	Reprolysin	ADAMTS10 ADAMTS19 ADAMTS6	5.10e-04	40	73	3	PF01421
Domain	ADAM_MEPRO	ADAMTS10 ADAMTS19 ADAMTS6	5.10e-04	40	73	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS10 ADAMTS19 ADAMTS6	5.10e-04	40	73	3	PS50214
Domain	Peptidase_M12B	ADAMTS10 ADAMTS19 ADAMTS6	5.10e-04	40	73	3	IPR001590
Domain	Disintegrin_dom	ADAMTS10 ADAMTS19 ADAMTS6	5.49e-04	41	73	3	IPR001762
Domain	ZINC_PROTEASE	MEP1B ADAMTS10 ADAMTS19 ADAMTS6	5.88e-04	98	73	4	PS00142
Domain	6-blade_b-propeller_TolB-like	VLDLR ELP1 HHIPL1	7.71e-04	46	73	3	IPR011042
Domain	-	SP140L SKI	9.70e-04	12	73	2	3.10.390.10
Domain	SAND_dom-like	SP140L SKI	9.70e-04	12	73	2	IPR010919
Domain	PI3/4_kinase_CS	ATR PI4KA	1.53e-03	15	73	2	IPR018936
Domain	-	ATR PI4KA	1.75e-03	16	73	2	1.10.1070.11
Domain	PI3Kc	ATR PI4KA	1.75e-03	16	73	2	SM00146
Domain	-	SP140L KDM5A BAZ2A NSD2 KDM5C KDM5D DNMT3B	1.84e-03	449	73	7	3.30.40.10
Domain	A/G_cyclase_CS	ADCY1 ADCY9	1.97e-03	17	73	2	IPR018297
Domain	Znf_RING/FYVE/PHD	SP140L KDM5A BAZ2A NSD2 KDM5C KDM5D DNMT3B	2.08e-03	459	73	7	IPR013083
Domain	PI3/4_kinase_cat_dom	ATR PI4KA	2.21e-03	18	73	2	IPR000403
Domain	PI3_PI4_kinase	ATR PI4KA	2.21e-03	18	73	2	PF00454
Domain	PI3_4_KINASE_3	ATR PI4KA	2.21e-03	18	73	2	PS50290
Domain	Nucleotide_cyclase	ADCY1 ADCY9	2.21e-03	18	73	2	IPR029787
Domain	PI3_4_KINASE_1	ATR PI4KA	2.21e-03	18	73	2	PS00915
Domain	PI3_4_KINASE_2	ATR PI4KA	2.21e-03	18	73	2	PS00916
Domain	-	ADCY1 ADCY9	2.21e-03	18	73	2	3.30.70.1230
Domain	GUANYLATE_CYCLASE_1	ADCY1 ADCY9	2.47e-03	19	73	2	PS00452
Domain	Guanylate_cyc	ADCY1 ADCY9	2.47e-03	19	73	2	PF00211
Domain	GUANYLATE_CYCLASE_2	ADCY1 ADCY9	2.47e-03	19	73	2	PS50125
Domain	A/G_cyclase	ADCY1 ADCY9	2.47e-03	19	73	2	IPR001054
Domain	CYCc	ADCY1 ADCY9	2.47e-03	19	73	2	SM00044
Domain	PWWP	NSD2 DNMT3B	2.74e-03	20	73	2	SM00293
Domain	SRCR	CD5L HHIPL1	3.02e-03	21	73	2	PF00530
Domain	Growth_fac_rcpt_	VLDLR EGFR MATN2 LAMC1	3.26e-03	156	73	4	IPR009030
Domain	PWWP	NSD2 DNMT3B	3.61e-03	23	73	2	PF00855
Domain	PWWP_dom	NSD2 DNMT3B	3.61e-03	23	73	2	IPR000313
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS10 ADAMTS19 ADAMTS6 THSD7B	1.43e-05	39	54	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS10 ADAMTS19 ADAMTS6 THSD7B	1.43e-05	39	54	4	MM15165
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS10 ADAMTS19 ADAMTS6 THSD7B	1.31e-04	68	54	4	M27303
Pathway	REACTOME_HDMS_DEMETHYLATE_HISTONES	KDM5A KDM5C KDM5D	1.81e-04	29	54	3	MM14934
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	GPC1 ADAMTS10 ADAMTS19 ADAMTS6 THSD7B	2.12e-04	143	54	5	M27275
Pathway	WP_GLUTATHIONE_AND_ONECARBON_METABOLISM	GGT1 GGT3P DNMT3B	3.19e-04	35	54	3	MM15815
Pathway	WP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION	ATP2B2 GGT1 ITPR1	3.47e-04	36	54	3	M39831
Pathway	REACTOME_DISEASES_OF_METABOLISM	GPC1 ADAMTS10 ADAMTS19 ADAMTS6 THSD7B GGT1	3.71e-04	250	54	6	M27554
Pathway	KEGG_GAP_JUNCTION	EGFR ADCY1 ADCY9 ITPR1	3.85e-04	90	54	4	M4013
Pubmed	Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.	KDM5A KDM5C KDM5D	3.85e-08	4	75	3	16541399
Pubmed	Increased expression of laminin-1 and collagen (IV) subunits in the aganglionic bowel of ls/ls, but not c-ret -/- mice.	COL4A2 LAMC1 RET	5.35e-07	8	75	3	8812145
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	HDAC4 KDM5A BAZ2A KDM5C KDM5D DNMT3B	1.20e-06	157	75	6	30186101
Pubmed	Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.	KDM5A KDM5C KDM5D	2.71e-06	13	75	3	24619213
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	CYFIP1 EGFR MARS1 PI4KA LAMC1 IDH3G VCL	4.34e-06	304	75	7	32235678
Pubmed	Mechanism of RET gene mediated EGFR signaling pathway on epithelial-mesenchymal transition, proliferation and apoptosis of papillary thyroid carcinoma cells.	EGFR RET	4.59e-06	2	75	2	32767330
Pubmed	Cardiac glycosides correct aberrant splicing of IKBKAP-encoded mRNA in familial dysautonomia derived cells by suppressing expression of SRSF3.	SRSF3 ELP1	4.59e-06	2	75	2	23711097
Pubmed	Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.	KDM5C KDM5D	4.59e-06	2	75	2	10441747
Pubmed	Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.	KDM5C KDM5D	4.59e-06	2	75	2	16416087
Pubmed	Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.	KDM5C KDM5D	4.59e-06	2	75	2	32081420
Pubmed	Elevated RET expression enhances EGFR activation and mediates EGFR inhibitor resistance in head and neck squamous cell carcinoma.	EGFR RET	4.59e-06	2	75	2	27090738
Pubmed	Combination EGFR and RET Inhibition in Acquired Resistance to Osimertinib in EGFR-Mutant NSCLC.	EGFR RET	4.59e-06	2	75	2	34344199
Pubmed	A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.	KDM5C KDM5D	4.59e-06	2	75	2	7524912
Pubmed	Loss of G-protein-signaling modulator 2 accelerates proliferation of lung adenocarcinoma via EGFR signaling pathway.	EGFR GPSM2	4.59e-06	2	75	2	32058048
Pubmed	EGFR mediates activation of RET in lung adenocarcinoma with neuroendocrine differentiation characterized by ASCL1 expression.	EGFR RET	4.59e-06	2	75	2	28460442
Pubmed	RET/PTC-induced cell growth is mediated in part by epidermal growth factor receptor (EGFR) activation: evidence for molecular and functional interactions between RET and EGFR.	EGFR RET	4.59e-06	2	75	2	18519677
Pubmed	ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions.	ADAMTS10 ADAMTS6	4.59e-06	2	75	2	27779234
Pubmed	RET finger protein expression is associated with prognosis in lung cancer with epidermal growth factor receptor mutations.	EGFR RET	4.59e-06	2	75	2	22524660
Pubmed	Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.	KDM5C KDM5D	4.59e-06	2	75	2	9060413
Pubmed	Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice.	GPC1 HDAC4 GCM1	5.29e-06	16	75	3	18163532
Pubmed	Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.	ADAMTS10 ADAMTS19 ADAMTS6	7.68e-06	18	75	3	35503090
Pubmed	The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3.	KDM5A KDM5C VCL	1.07e-05	20	75	3	23637629
Pubmed	RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3.	KDM5A KDM5C	1.37e-05	3	75	2	17320161
Pubmed	KDM5 family of demethylases promotes CD44-mediated chemoresistance in pancreatic adenocarcinomas.	KDM5A KDM5C	1.37e-05	3	75	2	37880235
Pubmed	Epidermal growth factor receptor and integrins control force-dependent vinculin recruitment to E-cadherin junctions.	EGFR VCL	1.37e-05	3	75	2	29487179
Pubmed	Fine mapping of the 9q31 Hirschsprung's disease locus.	ELP1 RET	1.37e-05	3	75	2	20361209
Pubmed	Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization.	KDM5A KDM5C	1.37e-05	3	75	2	38230606
Pubmed	E6 Protein Expressed by High-Risk HPV Activates Super-Enhancers of the EGFR and c-MET Oncogenes by Destabilizing the Histone Demethylase KDM5C.	EGFR KDM5C	1.37e-05	3	75	2	29339538
Pubmed	Identification of a mouse male-specific transplantation antigen, H-Y.	KDM5C KDM5D	1.37e-05	3	75	2	7544442
Pubmed	Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.	KDM5A KDM5C	1.37e-05	3	75	2	26645689
Pubmed	Driver genes as predictive indicators of brain metastasis in patients with advanced NSCLC: EGFR, ALK, and RET gene mutations.	EGFR RET	1.37e-05	3	75	2	31769228
Pubmed	Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidney.	GGT1 GGT3P	1.37e-05	3	75	2	2573352
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS10 ADAMTS19 ADAMTS6 THSD7B	2.16e-05	75	75	4	20637190
Pubmed	The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.	KDM5C KDM5D	2.75e-05	4	75	2	17320160
Pubmed	CC2D1A and CC2D1B regulate degradation and signaling of EGFR and TLR4.	EGFR CC2D1B	2.75e-05	4	75	2	27769858
Pubmed	Two types of abnormal genes for plasminogen in families with a predisposition for thrombosis.	PLGLA PLGLB1	2.75e-05	4	75	2	1986355
Pubmed	KIF5B-RET Fusion gene may coincide oncogenic mutations of EGFR or KRAS gene in lung adenocarcinomas.	EGFR RET	2.75e-05	4	75	2	26268359
Pubmed	A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.	KDM5C KDM5D	2.75e-05	4	75	2	7951230
Pubmed	Requirement for phosphatidylinositol transfer protein in epidermal growth factor signaling.	EGFR PI4KA	2.75e-05	4	75	2	7761838
Pubmed	Multiple members of the plasminogen-apolipoprotein(a) gene family associated with thrombosis.	PLGLA PLGLB1	2.75e-05	4	75	2	1554698
Pubmed	Central role of the threonine residue within the p+1 loop of receptor tyrosine kinase in STAT3 constitutive phosphorylation in metastatic cancer cells.	EGFR RET	2.75e-05	4	75	2	15485908
Pubmed	X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.	KDM5C KDM5D	2.75e-05	4	75	2	32732223
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	ADAMTS10 COL4A2 ZBTB48 SOBP MARS1 PI4KA ELP1 LAMC1 CCDC85A DNMT3B ZNF331	2.82e-05	1124	75	11	21900206
Pubmed	Phenotypic characterization of Ggt1(dwg/dwg) mice,a mouse model for hereditary γ-glutamyltransferase deficiency.	GGT1 GGT3P	4.57e-05	5	75	2	23615310
Pubmed	Genomic profiling in a homogeneous molecular subtype of non-small cell lung cancer: An effort to explore new drug targets.	EGFR RET	4.57e-05	5	75	2	26853422
Pubmed	gamma-glutamyltranspeptidase-deficient knockout mice as a model to study the relationship between glutathione status, mitochondrial function, and cellular function.	GGT1 GGT3P	4.57e-05	5	75	2	11003618
Pubmed	Cloning and nucleotide sequence of human gamma-glutamyl transpeptidase.	GGT1 GGT3P	4.57e-05	5	75	2	2904146
Pubmed	E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning.	EGFR VCL	4.57e-05	5	75	2	29093447
Pubmed	Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species.	GGT1 GGT3P	4.57e-05	5	75	2	10392451
Pubmed	Hyperoxia-induced lung injury in gamma-glutamyl transferase deficiency is associated with alterations in nitrosative and nitrative stress.	GGT1 GGT3P	4.57e-05	5	75	2	19850887
Pubmed	Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice.	GGT1 GGT3P	4.57e-05	5	75	2	12810527
Pubmed	Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice.	GGT1 GGT3P	4.57e-05	5	75	2	8755578
Pubmed	Reproductive defects in gamma-glutamyl transpeptidase-deficient mice.	GGT1 GGT3P	4.57e-05	5	75	2	11089562
Pubmed	N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice.	GGT1 GGT3P	4.57e-05	5	75	2	26977590
Pubmed	Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia.	GGT1 GGT3P	4.57e-05	5	75	2	12225953
Pubmed	Identification of a sixth promoter that directs the transcription of gamma-glutamyl transpeptidase type III RNA in mouse.	GGT1 GGT3P	4.57e-05	5	75	2	7775425
Pubmed	Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility.	GGT1 GGT3P	4.57e-05	5	75	2	9139708
Pubmed	Analysis of site-specific glycosylation of renal and hepatic γ-glutamyl transpeptidase from normal human tissue.	GGT1 GGT3P	4.57e-05	5	75	2	20622017
Pubmed	Accelerated methylmercury elimination in gamma-glutamyl transpeptidase-deficient mice.	GGT1 GGT3P	4.57e-05	5	75	2	9546365
Pubmed	gamma-Glutamyl transpeptidase. What does the organization and expression of a multipromoter gene tell us about its functions?	GGT1 GGT3P	4.57e-05	5	75	2	7485380
Pubmed	Accumulation of DNA damage in the organs of mice deficient in gamma-glutamyltranspeptidase.	GGT1 GGT3P	4.57e-05	5	75	2	10751614
Pubmed	Type VI RNA is the major gamma-glutamyl transpeptidase RNA in the mouse small intestine.	GGT1 GGT3P	4.57e-05	5	75	2	7523374
Pubmed	Physical and genetic maps of the deafwaddler region on distal mouse Chr 6.	ATP2B2 ITPR1	4.57e-05	5	75	2	9615221
Pubmed	Cardio-reno-hepatic interactions in acute heart failure: the role of γ-glutamyl transferase.	GGT1 GGT3P	4.57e-05	5	75	2	24698228
Pubmed	gamma-Glutamyl transferase (GGT) deficiency in the GGTenu1 mouse results from a single point mutation that leads to a stop codon in the first coding exon of GGT mRNA.	GGT1 GGT3P	4.57e-05	5	75	2	10474818
Pubmed	Lung lining fluid glutathione attenuates IL-13-induced asthma.	GGT1 GGT3P	4.57e-05	5	75	2	18063838
Pubmed	Gamma-glutamyltranspeptidase knockout mice as a model for understanding the consequences of diminished glutathione on T cell-dependent immune responses.	GGT1 GGT3P	4.57e-05	5	75	2	10940879
Pubmed	Cataract development in gamma-glutamyl transpeptidase-deficient mice.	GGT1 GGT3P	4.57e-05	5	75	2	11095909
Pubmed	Expression of gamma-glutamyl transpeptidase in midgestation mouse yolk sac and mouse visceral yolk sac carcinoma cells.	GGT1 GGT3P	4.57e-05	5	75	2	7641802
Pubmed	The mouse skin carcinogenesis model.	GGT1 GGT3P	4.57e-05	5	75	2	9627710
Pubmed	Gamma-glutamyl transpeptidase and its role in melanogenesis: redox reactions and regulation of tyrosinase.	GGT1 GGT3P	4.57e-05	5	75	2	12453183
Pubmed	Splicing variations in the ligand-binding domain of ApoER2 results in functional differences in the binding properties to Reelin.	VLDLR ITPR1	4.57e-05	5	75	2	19167437
Pubmed	Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney.	GGT1 GGT3P	4.57e-05	5	75	2	2891746
Pubmed	Expression of multiple gamma-glutamyltransferase genes in man.	GGT1 GGT3P	4.57e-05	5	75	2	7906515
Pubmed	Liver-Specific Overexpression of Gamma-Glutamyltransferase Ameliorates Insulin Sensitivity of Male C57BL/6 Mice.	GGT1 GGT3P	4.57e-05	5	75	2	28660214
Pubmed	Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice.	GGT1 GGT3P	4.57e-05	5	75	2	12468440
Pubmed	Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene.	GGT1 GGT3P	4.57e-05	5	75	2	8566783
Pubmed	Therapeutic Effect of GGsTop, Selective Gamma-glutamyl Transpeptidase Inhibitor, on a Mouse Model of 5-Fluorouracil-induced Oral Mucositis.	GGT1 GGT3P	4.57e-05	5	75	2	30591459
Pubmed	In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knockout mice.	GGT1 GGT3P	4.57e-05	5	75	2	11795900
Pubmed	BAP1 is required prenatally for differentiation and maintenance of postnatal murine enteric nervous system.	HDAC4 RET	4.57e-05	5	75	2	38690732
Pubmed	Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma.	GGT1 GGT3P	4.57e-05	5	75	2	25132819
Pubmed	Characterization of the dwg mutations: dwg and dwg(Bayer) are new mutant alleles of the Ggt1 gene.	GGT1 GGT3P	4.57e-05	5	75	2	19760322
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	KDM5A KDM5C KDM5D	5.02e-05	33	75	3	26864203
Pubmed	The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.	EGFR RET GGT1 GGT3P	5.47e-05	95	75	4	20843830
Pubmed	Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.	GPC1 COL4A2 LAMC1 PRG4	5.94e-05	97	75	4	27559042
Pubmed	Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.	MATN2 LAMC1 LTF ADCY1	6.18e-05	98	75	4	19834535
Pubmed	Gamma-glutamyltranspeptidase stimulates receptor activator of nuclear factor-kappaB ligand expression independent of its enzymatic activity and serves as a pathological bone-resorbing factor.	GGT1 GGT3P	6.84e-05	6	75	2	14634009
Pubmed	Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock.	KDM5A KDM5C	6.84e-05	6	75	2	21960634
Pubmed	Six mRNAs with different 5' ends are encoded by a single gamma-glutamyltransferase gene in mouse.	GGT1 GGT3P	6.84e-05	6	75	2	8101000
Pubmed	Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes.	GGT1 GGT3P	6.84e-05	6	75	2	8104871
Pubmed	Disruption of gamma-glutamyl leukotrienase results in disruption of leukotriene D(4) synthesis in vivo and attenuation of the acute inflammatory response.	GGT1 GGT3P	6.84e-05	6	75	2	11463821
Pubmed	Effect of atorvastatin on the expression of gamma-glutamyl transferase in aortic atherosclerotic plaques of apolipoprotein E-knockout mice.	GGT1 GGT3P	6.84e-05	6	75	2	25326709
Pubmed	Gamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivo.	GGT1 GGT3P	6.84e-05	6	75	2	12163373
Pubmed	Ablation of Mrds1/Ofcc1 induces hyper-γ-glutamyl transpeptidasemia without abnormal head development and schizophrenia-relevant behaviors in mice.	GGT1 GGT3P	6.84e-05	6	75	2	22242126
Pubmed	Molecular genetic analysis of distal mouse chromosome 6 defines gene order and positions of the deafwaddler and opisthotonos mutations.	ATP2B2 ITPR1	6.84e-05	6	75	2	8530061
Pubmed	Overexpression of gamma-glutamyltransferase in transgenic mice accelerates bone resorption and causes osteoporosis.	GGT1 GGT3P	6.84e-05	6	75	2	17363454
Pubmed	Four distinct membrane-bound dipeptidase RNAs are differentially expressed and show discordant regulation with gamma-glutamyl transpeptidase.	GGT1 GGT3P	6.84e-05	6	75	2	8663190
Pubmed	Histone deacetylase 3 binds to and regulates the GCMa transcription factor.	HDAC4 GCM1	6.84e-05	6	75	2	16528103
Pubmed	Distinct turnover of alternatively spliced isoforms of the RET kinase receptor mediated by differential recruitment of the Cbl ubiquitin ligase.	EGFR RET	6.84e-05	6	75	2	15677445
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	ATR EGFR PI4KA TUT7 LAMC1	7.80e-05	202	75	5	33005030
GeneFamily	PHD finger proteins	SP140L KDM5A BAZ2A NSD2 KDM5C KDM5D	2.74e-07	90	54	6	88
GeneFamily	AT-rich interaction domain containing	KDM5A KDM5C KDM5D	1.12e-05	15	54	3	418
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS10 ADAMTS19 ADAMTS6	2.36e-05	19	54	3	50
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM5A KDM5C KDM5D	4.88e-05	24	54	3	485
GeneFamily	Adenylate cyclases\|Deafness associated genes	ADCY1 ADCY9	3.88e-04	10	54	2	53
GeneFamily	CD molecules\|Gamma-glutamyltransferases	GGT1 GGT3P	6.69e-04	13	54	2	564
GeneFamily	PWWP domain containing	NSD2 DNMT3B	1.95e-03	22	54	2	1147
Coexpression	DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN	GPC1 TRIM16 COL4A2 ATR KDM5C ADCY9 ITPR1	1.43e-05	276	75	7	M3063
Coexpression	GSE10240_CTRL_VS_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP	KIAA0930 ZBTB48 BAZ2A TUT7 HHIPL1 ITPR1	2.38e-05	200	75	6	M302
Coexpression	GSE45365_NK_CELL_VS_CD11B_DC_MCMV_INFECTION_UP	COL4A2 HDAC4 MARS1 PI4KA FAM53B RET	2.38e-05	200	75	6	M9956
ToppCell	LV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	COL4A2 ADAMTS19 EGFR SOBP LAMC1 ADCY1	8.28e-07	190	75	6	12992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell	AT1_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	COL4A2 EGFR CNKSR2 CCDC85A GGT1 VCL	1.02e-06	197	75	6	80d81be244c94c435accb643449b4ce6a3462c7f
ToppCell	AT1_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	COL4A2 KDM5A CNKSR2 CCDC85A GGT1	1.20e-05	176	75	5	458720776b0151cd55acc352d509599cb62f0ca8
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM16 ATR RET ADCY9 FGL2	1.26e-05	178	75	5	408e41c853f608965cef9111fb87fdc311cdc7a8
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL4A2 ADAMTS19 MATN2 PRG4 ADCY1	1.69e-05	189	75	5	c392491aabe8a3e90974ab2ea123bbbe5200439d
ToppCell	(2)_Fibroblasts-(21)_Fibro-2\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	COL4A2 VLDLR EGFR PRG4 FGL2	1.73e-05	190	75	5	d2afa08ad868acc6fce308ec21b0bf93591d4010
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 EGFR LAMC1 RET FGL2	1.82e-05	192	75	5	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	COL4A2 ADAMTS19 EGFR SOBP LAMC1	1.87e-05	193	75	5	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 EGFR LAMC1 PRG4 FGL2	1.87e-05	193	75	5	45b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCell	Epithelial_cells-AT1_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	COL4A2 CNKSR2 CCDC85A GGT1 VCL	2.01e-05	196	75	5	6c99d29162848161c1f166a032320f87a5d5a631
ToppCell	ASK440-Epithelial-Type_1\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	COL4A2 PLAAT4 POLR2L CNKSR2 VCL	2.06e-05	197	75	5	782449c522c9e16e72bf999a73090688a3aefe06
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MATN2 CNKSR2 HHIPL1 THSD7B FGL2	2.16e-05	199	75	5	fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	COL4A2 KDM5A CNKSR2 CCDC85A GGT1	2.16e-05	199	75	5	5a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A2 CHST1 ADCY1 CCDC85A	1.65e-04	163	75	4	ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD7B TMPRSS7 EXOSC7 ADCY1	1.73e-04	165	75	4	a6c6de17fec678ad0cac3138dde3a14cc39ffd26
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEP1B GCM1 GCDH GGT1	1.85e-04	168	75	4	b14fd50232887b6dca1f39014d43c6f66e5c3b5c
ToppCell	COVID-19_Mild-Neu_2\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	GPSM2 LTF PRG4 GGT1	2.03e-04	172	75	4	f5fd08b42c002d4693646b27e7b708eceb49524f
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	EGFR PLGLB1 PRG4 CCDC85A	2.07e-04	173	75	4	e05cddf5bf63cf419343ff229453327519765be8
ToppCell	AT1_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	COL4A2 EGFR CCDC85A VCL	2.07e-04	173	75	4	3afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	HDAC4 CCDC85C IDH3G DNMT3B	2.07e-04	173	75	4	b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	EGFR PLGLB1 PRG4 CCDC85A	2.07e-04	173	75	4	74ad5ed33821b8816c9c8e67c50ee4496ba18e2f
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAB21L3 EGFR RET CCDC85A	2.12e-04	174	75	4	b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MAB21L3 EGFR RET CCDC85A	2.12e-04	174	75	4	71730503be3d9c839c4c9e950145e2101d682a1c
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	COL4A2 GCM1 LAMC1 PRG4	2.12e-04	174	75	4	fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MAB21L3 EGFR RET CCDC85A	2.12e-04	174	75	4	ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAB21L3 EGFR RET CCDC85A	2.12e-04	174	75	4	cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCell	TCGA-Colorectal-Recurrent_Tumor\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PLGLA CD5L PLGLB1 ATP2B2	2.17e-04	175	75	4	7f74961436f88c0e380819095e6104489914d765
ToppCell	TCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PLGLA CD5L PLGLB1 ATP2B2	2.17e-04	175	75	4	bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCell	BAL-Control-cDC_11\|Control / Compartment, Disease Groups and Clusters	SPDYE3 ANKRD24 ADCY1 FGL2	2.17e-04	175	75	4	daf014e15a354956e9149c83fd89d0af0d07eb00
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLAAT4 GPSM2 EXOSC7 ADCY1	2.26e-04	177	75	4	8e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEP1B CHST1 ATP2B2 ITPR1	2.31e-04	178	75	4	a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCell	facs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATR POLR2L PPM1M ADCY9	2.31e-04	178	75	4	89f0537459a321ded956bf70ad56fefc0854f8b0
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEP1B CHST1 ATP2B2 ITPR1	2.31e-04	178	75	4	1bddbc083c36657bd6910f7466126ab325e88176
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EGFR ADAMTS6 LTF THSD7B	2.36e-04	179	75	4	cd7f0e8f4abb2a2bac366c8910c8c5fda841dbce
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS19 POLR2L CCDC85C CHST1	2.36e-04	179	75	4	c1c0b7186a0eab8c76404b95f1cf8d64b1b45cb1
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEP1B CHST1 ATP2B2 ITPR1	2.36e-04	179	75	4	a3922476f33d2e4137a12dbda21a1703dff79684
ToppCell	Leuk-UTI-Lymphocyte-B-B_intermediate\|Leuk-UTI / Disease, Lineage and Cell Type	ADAMTS6 SOBP CNKSR2 CCDC85A	2.36e-04	179	75	4	01933f6fa94d7032ed403a6cae6985cafa820043
ToppCell	LA-01._Fibroblast_I\|LA / Chamber and Cluster_Paper	ADAMTS19 EGFR SOBP LAMC1	2.36e-04	179	75	4	dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell	NS-moderate-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAB21L3 EGFR THSD7B RET	2.41e-04	180	75	4	8af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL4A2 LAMC1 VCL RASGRP2	2.41e-04	180	75	4	64956a85c404a2ea7e4eaf6f95ebcc52c198b7cc
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Dendritic_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATR POLR2L PPM1M ADCY9	2.41e-04	180	75	4	710526abedc8e0f9ba19ad69220df4c9468ada8f
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZNF234 EGFR ABCB8 FGL2	2.52e-04	182	75	4	c6172aca2475bf0948a78e39f0dae6388504a915
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A2 SOBP MATN2 LAMC1	2.52e-04	182	75	4	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 MATN2 LAMC1 FGL2	2.52e-04	182	75	4	f4b74c2756989812abe4e7055ec8918f69d56025
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPC1 MATN2 CNKSR2 PRG4	2.52e-04	182	75	4	a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell	COVID-19_Severe-gd_T\|COVID-19_Severe / Disease condition and Cell class	TUT7 FAM53B VCL FGL2	2.62e-04	184	75	4	791f1bcb954aadc63d4117c400537d036f68734d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC4 SOBP ADCY9 ZNF331	2.68e-04	185	75	4	a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell	Mild_COVID-19-Epithelial-AT1/AT2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	MAB21L3 EGFR RET CCDC85A	2.68e-04	185	75	4	c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	COL4A2 ADAMTS19 EGFR LAMC1	2.79e-04	187	75	4	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	AT1_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	COL4A2 CNKSR2 CCDC85A VCL	2.79e-04	187	75	4	f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A2 EGFR CCDC85A VCL	2.79e-04	187	75	4	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CYFIP1 IDH3G EXOSC7 FGL2	2.79e-04	187	75	4	5917bdfe84cf5941e21b415aebbab3090cc5d576
ToppCell	human_hepatoblastoma-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ADAMTS6 SOBP ELP1 THSD7B	2.79e-04	187	75	4	f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell	moderate-Epithelial-Ionocyte\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MAB21L3 EGFR THSD7B RET	2.79e-04	187	75	4	3e3fe2d5712a0ac477cddefe56705d4b8d8f7eac
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	COL4A2 MATN2 CHST1 ADCY1	2.79e-04	187	75	4	be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS19 LAMC1 HHIPL1 RET	2.85e-04	188	75	4	aa516273cdde53c8c0295f06830972388f890c97
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A2 ADCY9 VCL RASGRP2	2.85e-04	188	75	4	a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCell	LV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	COL4A2 EGFR SOBP ZNF331	2.90e-04	189	75	4	3922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR SOBP MATN2 LAMC1	2.90e-04	189	75	4	f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADAMTS19 SOBP MATN2 ADCY1	2.90e-04	189	75	4	473b01c9162b12b90a617c600238436177a0d18d
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR SOBP MATN2 LAMC1	2.90e-04	189	75	4	378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A2 VLDLR VCL RASGRP2	2.90e-04	189	75	4	d0c7549be4f77520c23dddf4f94d0fcad0081e37
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 EGFR LAMC1 RET	2.96e-04	190	75	4	1121eb607a984c59fbffe7220837fc178745aa55
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 EGFR LAMC1 FGL2	2.96e-04	190	75	4	bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 EGFR LAMC1 FGL2	2.96e-04	190	75	4	e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 EGFR LAMC1 RET	2.96e-04	190	75	4	048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 EGFR LAMC1 FGL2	2.96e-04	190	75	4	ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCell	facs-GAT-Fat-3m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYFIP1 MATN2 LTF VCL	2.96e-04	190	75	4	1d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A2 ADCY9 VCL RASGRP2	2.96e-04	190	75	4	951e067d14412db67dc3babcdf61e41717d7b429
ToppCell	(4)_Endothelial_cells-(40)_EC-arterial\|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis	TRIM16 RET CCDC85A FGL2	2.96e-04	190	75	4	ff774faf3f12759d11e50ed7d189288bb79e22e1
ToppCell	facs-Marrow-KLS-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 KIAA0930 ABCB8 FGL2	2.96e-04	190	75	4	c03c735a0ed850bf460a1847f5e2dd61753e577d
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CHST1 THSD7B ADCY1 CCDC85A	2.96e-04	190	75	4	7ba2be2630183df86de21689289a8620a4cd507e
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 VLDLR MATN2 FGL2	2.96e-04	190	75	4	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM16 CHST1 VCL RASGRP2	3.02e-04	191	75	4	df8cdbc26443e55a203cbafa21b0952a2a55b9bf
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR EGFR MATN2 LAMC1	3.02e-04	191	75	4	6cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR EGFR MATN2 LAMC1	3.02e-04	191	75	4	850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR EGFR MATN2 LAMC1	3.02e-04	191	75	4	8b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR LAMC1 RET ITPR1	3.02e-04	191	75	4	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	COL4A2 EGFR SOBP LAMC1	3.02e-04	191	75	4	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR MATN2 LAMC1 RET	3.08e-04	192	75	4	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	droplet-Heart-nan-18m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 KLHL38 VLDLR ADCY1	3.08e-04	192	75	4	0bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	COL4A2 EGFR SOBP LAMC1	3.08e-04	192	75	4	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	EGFR SOBP LAMC1 ITPR1	3.08e-04	192	75	4	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR MATN2 LAMC1 RET	3.08e-04	192	75	4	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 VLDLR EGFR LAMC1	3.08e-04	192	75	4	2d9e2262f1342fe17735f21f733c029d1275e955
ToppCell	Endothelial-Endothelial-B\|Endothelial / shred on cell class and cell subclass (v4)	TRIM16 COL4A2 CHST1 RASGRP2	3.08e-04	192	75	4	f8d7bd81e031d09a557722627c2f6180811cc6ab
ToppCell	droplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 KLHL38 VLDLR ADCY1	3.08e-04	192	75	4	d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR EGFR LAMC1 PRG4	3.14e-04	193	75	4	316ebdf15f75d88c348f909b643fcd315364ca84
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR EGFR LAMC1 PRG4	3.14e-04	193	75	4	1afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 EGFR LAMC1 PRG4	3.14e-04	193	75	4	49600db68ed65cafc67bd45a285b364e4f5f88af
ToppCell	droplet-Fat-Scat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR EGFR LAMC1 PRG4	3.14e-04	193	75	4	8dc6db335678f3a5cfd36026ad811fed8d9cb4bc
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	COL4A2 EGFR SOBP LAMC1	3.21e-04	194	75	4	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 EGFR MATN2 FGL2	3.21e-04	194	75	4	ce32e60bcea1b8baf496ce9050832bc8c77d8434
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 EGFR MATN2 FGL2	3.21e-04	194	75	4	a1dc157148885cc8d3685ac81a1f4e3562aeecc9
ToppCell	distal-Hematologic-Nonclassical_Monocyte-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TUT7 FAM53B RASGRP2 FGL2	3.21e-04	194	75	4	f1cabb198ab32deaf299899c5e8f42d861b8c574
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRIM16 COL4A2 CHST1 VCL	3.21e-04	194	75	4	8deeb3e00237e3d9ad5a1457cd0061576421b9e9
ToppCell	facs-Heart-RA-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 EGFR MATN2 LAMC1	3.21e-04	194	75	4	bc945450b350f597c3ff910d3a14a533d90086a8
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRIM16 COL4A2 CHST1 VCL	3.21e-04	194	75	4	b81801fb16e8bd0d6083fe32866051d3c60f3dc7
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	COL4A2 EGFR SOBP LAMC1	3.21e-04	194	75	4	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	facs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR EGFR MATN2 LAMC1	3.27e-04	195	75	4	69a29d03e664b72f32d41876510c62345c3aed31
Drug	genistein; Down 200; 10uM; HL60; HT_HG-U133A	KIAA0930 BAZ2A FAM53B GCDH RET IDH3G EXOSC7 RASGRP2	1.96e-07	188	75	8	1176_DN
Drug	Fibrin	PLGLA PLGLB1 FGL2	2.84e-06	9	75	3	CID000439199
Drug	LMWH	PLGLA GPC1 EGFR LAMC1 LTF PLGLB1 PRG4 ADCY1 ADCY9 FGL2 ITPR1	1.06e-05	663	75	11	CID000000772
Disease	syndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)	KDM5A KDM5C KDM5D	5.33e-08	4	71	3	DOID:0060809 (implicated_via_orthology)
Disease	syndromic intellectual disability (implicated_via_orthology)	KDM5A KDM5C KDM5D	7.31e-06	16	71	3	DOID:0050888 (implicated_via_orthology)
Disease	aortic valve disease (implicated_via_orthology)	ADAMTS19 EGFR	8.51e-05	6	71	2	DOID:62 (implicated_via_orthology)
Disease	age at diagnosis, coronary atherosclerosis measurement	COL4A2 HHIPL1	8.51e-05	6	71	2	EFO_0004918, EFO_0007938
Disease	hepatocellular carcinoma (is_marker_for)	GPC1 HDAC4 EGFR KDM5C GGT1 DNMT3B	8.80e-05	301	71	6	DOID:684 (is_marker_for)
Disease	alcohol use disorder (implicated_via_orthology)	EGFR KDM5A KDM5C KDM5D ADCY1	1.09e-04	195	71	5	DOID:1574 (implicated_via_orthology)
Disease	aflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)	GGT1 GGT3P	1.19e-04	7	71	2	DOID:5022 (biomarker_via_orthology)
Disease	alcohol dependence (biomarker_via_orthology)	GGT1 GGT3P	1.58e-04	8	71	2	DOID:0050741 (biomarker_via_orthology)
Disease	Nonsyndromic Hearing Loss and Deafness, Autosomal Recessive	GPSM2 ATP2B2 ADCY1	2.56e-04	51	71	3	cv:CN043650
Disease	Malignant Neoplasms	ATR EGFR LTF RET	2.62e-04	128	71	4	C0006826
Disease	Small cell carcinoma of lung	COL4A2 EGFR ADCY1	3.03e-04	54	71	3	C0149925
Disease	autism spectrum disorder (implicated_via_orthology)	KDM5A KDM5C LAMC1 KDM5D	5.03e-04	152	71	4	DOID:0060041 (implicated_via_orthology)
Disease	N-acetylmethionine measurement	CHST1 ITPR1	5.87e-04	15	71	2	EFO_0021427
Disease	balding measurement	GPC1 COL4A2 HDAC4 LAMC1 FAM53B CNKSR2 ITPR1 DNMT3B	6.23e-04	792	71	8	EFO_0007825
Disease	Inguinal hernia	HDAC4 ADAMTS6 ABHD16A CCDC85A VCL	6.48e-04	287	71	5	HP_0000023
Disease	Prostatic Neoplasms	ATR EGFR BAZ2A LAMC1 GGT1 ITPR1 DNMT3B	6.99e-04	616	71	7	C0033578
Disease	Malignant neoplasm of prostate	ATR EGFR BAZ2A LAMC1 GGT1 ITPR1 DNMT3B	6.99e-04	616	71	7	C0376358
Disease	intellectual disability (implicated_via_orthology)	KDM5A KDM5C KDM5D	7.96e-04	75	71	3	DOID:1059 (implicated_via_orthology)
Disease	Nonsyndromic genetic hearing loss	GPSM2 ATP2B2 ADCY1	8.27e-04	76	71	3	cv:C5680182
Disease	Malignant neoplasm of endometrium	ATR EGFR	8.52e-04	18	71	2	C0007103
Disease	Carcinoma in situ of endometrium	ATR EGFR	8.52e-04	18	71	2	C0346191
Disease	central corneal thickness	ADAMTS19 ADAMTS6 FAM53B CHST1 SKI	9.03e-04	309	71	5	EFO_0005213
Disease	myocardial infarction	COL4A2 HDAC4 LAMC1 HHIPL1 SKI	1.57e-03	350	71	5	EFO_0000612
Disease	corpus collosum mid-posterior volume measurement	VLDLR EGFR	1.65e-03	25	71	2	EFO_0010300
Disease	corpus callosum volume measurement	EGFR LAMC1 FAM53B	1.83e-03	100	71	3	EFO_0010299
Disease	suntan	KIAA0930 DEF8 DNMT3B	1.99e-03	103	71	3	EFO_0004279

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGAGSREECAAKCEE	PLGLB1	41	Q02325
EGGLCQTCRDRFLEL	DNMT3B	451	Q9UBC3
VCRKGDNDEFLLLCD	BAZ2A	1681	Q9UIF9
DNDEFLLLCDGCDRG	BAZ2A	1686	Q9UIF9
EECNGRRAKLLACDG	ABHD16A	246	O95870
GECRCTEGDEAIKGL	COL4A2	481	P08572
KDVAVLCRELGCGAA	CD5L	56	O43866
RRICKRFGADVTCGE	DUS3L	321	Q96G46
LGKCEAAEAEAGRLR	ANKRD24	751	Q8TF21
GEDFLCLEGKEFNRR	ATP2B2	751	Q01814
GCDRVLGSDLREDKC	ADAMTS10	681	Q9H324
LGSDLREDKCRVCGG	ADAMTS10	686	Q9H324
ILGSDAREDRCRVCG	ADAMTS6	696	Q9UKP5
RERKCPGLDSEARDC	ADAMTS19	656	Q8TE59
REGDLLTKERLCCGL	CYFIP1	1076	Q7L576
LCEVFCRDRKVLREG	GGT3P	191	A6NGU5
ELALEGERLCKSGDC	GPSM2	26	P81274
GKCECIRGRKATLEE	HDAC4	696	P56524
ECLEGFRLAEDGKRC	MATN2	591	O00339
CKCSEGFVLAEDGRR	MATN2	631	O00339
DLDKGCTVEELLRGC	RASGRP2	6	Q7LDG7
DARRKCESGGFICKL	ITPR1	1651	Q14643
GCCDEGRDAELTRRF	HHIPL1	46	Q96JK4
GDGCLDDLCSRKVSR	GPC1	491	P35052
SRGDEDDKLLFCDGC	KDM5D	321	Q9BY66
REVCGLGCFKDDRIV	KIAA0930	16	Q6ICG6
ELCCFLDDDRQKGRK	CCDC85C	86	A6NKD9
CALDEDCGRRAEPAA	FAM53B	381	Q14153
KGEGKRQSEDECFRC	NSD2	1231	O96028
RCGVSELEKEGLRCR	PI4KA	1811	P42356
GEEECVLGLTDRCRF	ELP1	616	O95163
DLRVDGRGCEDYRCV	EXOSC7	21	Q15024
LGAGSREECAAKCEE	PLGLA	41	Q15195
RGNNEDKLLLCDGCD	KDM5A	301	P29375
LEQLDEDGGCRRKCF	MAB21L3	246	Q8N8X9
RGRECVDKCNLLEGE	EGFR	531	P00533
RGLRACDEEFACPEL	ADCY1	31	Q08828
GLRFKDDFPELCCRA	ATR	1181	Q13535
KLGDGLFLQCCREVA	IDH3G	226	P51553
ARCEDGCIRGFLLEK	GCDH	226	Q92947
ERCKNLSAIGLGECE	FBXL3	356	Q9UKT7
VCGRDCLAEEGRKIY	GCM1	81	Q9NP62
EAGEAAKARRCERGL	CC2D1B	186	Q5T0F9
DLFGRFDRLCEETKC	ADCY9	421	O60503
RGRFGKAIEKDDCDE	ADCY9	1321	O60503
RDLCCFLDDDRQKGK	CCDC85A	106	Q96PX6
AKGFVCELCREGDVL	DEF8	446	Q6ZN54
VRLESRGKCEEAGEC	FGL2	41	Q14314
KDDGRCECREGFVGN	LAMC1	996	P11047
VRDGKAECRCQSGED	MEP1B	621	Q16820
LEACRCRAEELGRGI	ABCB8	361	Q9NUT2
KCLRDGAGDVAFIRE	LTF	216	P02788
KRERLEDVVGGCCYR	PLAAT4	61	Q9UL19
RNLDECEVCRDGGEL	SP140L	401	Q9H930
KGRCFESFERGRECD	PRG4	71	Q92954
QARVCDKGCEAGRLR	SKI	646	P12755
LEEGDCVRKCGLLNL	CHST1	176	O43916
RRISCKDLGRGDCEG	CNKSR2	561	Q8WXI2
RGEKLFVCEECGHRA	ZBTB48	431	P10074
DAVRELDGRTLCGCR	SRSF3	61	P84103
LICDGFRDCENGRDE	TMPRSS7	536	Q7RTY8
GDGERRLQFCSAKCL	SOBP	241	A7XYQ1
LGCKRKRECLDESDD	SPDYE3	121	A6NKU9
SLGCKRKRECLDESD	SPDYE3	266	A6NKU9
CGKLCIRRCEFGAEE	PPM1M	91	Q96MI6
AGLRLCLDNECADFR	SOGA1	441	O94964
ELCAGKERREILGTC	VCL	311	P18206
ECKDCGKAFRRGDEL	ZNF331	216	Q9NQX6
EGDALDALGLKRYCC	POLR2L	31	P62875
VSKRRLECEECGGLG	RET	521	P07949
CEECGKGFSRRADLK	ZNF234	486	Q14588
ECKECGRAFIRGSLL	ZNF420	336	Q8TAQ5
CKGIDRKGEERNSCI	TRIM16	446	O95361
SKECGEGLRFRAVAC	THSD7B	956	Q9C0I4
KDLREKRCFICGREG	TUT7	1446	Q5VYS8
EEARGDQCDKCGKLI	MARS1	411	P56192
CRGCKIDCGEDRAFI	USP32	1176	Q8NFA0
DCAAGFELIDRKTCG	VLDLR	381	P98155
LCEVFCRDRKVLREG	GGT1	191	P19440
CALELRDYLGDDGLC	KLHL38	176	Q2WGJ6
SRGDEDDKLLLCDGC	KDM5C	331	P41229