Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionNotch binding

JAG2 SNED1 ATRNL1 MEGF10 NOTCH1 JAG1 NOTCH4

5.42e-1527297GO:0005112
GeneOntologyMolecularFunctioncalcium ion binding

JAG2 LRP1 LRP2 CRELD2 SNED1 OIT3 EGF MEGF6 LRP1B AGRN NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

1.70e-147492915GO:0005509
GeneOntologyMolecularFunctioncargo receptor activity

SCARF1 LRP1 LRP2 LRP1B MEGF10

1.36e-0785295GO:0038024
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP2 LRP1B

1.52e-0616293GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 LRP2 LRP1B

3.60e-0621293GO:0030228
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMA3 CRELD2 LAMB1 TNC AGRN

6.93e-06188295GO:0005201
GeneOntologyMolecularFunctionscavenger receptor activity

SCARF1 LRP1 MEGF10

7.87e-0627293GO:0005044
GeneOntologyMolecularFunctionstructural molecule activity

LAMA3 CRELD2 LAMB1 LAMC3 TNC AGRN KRT81 JAG1

2.83e-05891298GO:0005198
GeneOntologyMolecularFunctionproteoglycan binding

LRP1 TNC AGRN

5.47e-0551293GO:0043394
GeneOntologyMolecularFunctionintegrin binding

LAMB1 ADAM23 TNC ITGB7

1.14e-04175294GO:0005178
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

LRP1 AGRN

8.07e-0429292GO:0043395
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

LRP1 LRP2

1.46e-0339292GO:0070325
GeneOntologyMolecularFunctiongrowth factor activity

JAG2 EGF JAG1

1.98e-03173293GO:0008083
GeneOntologyBiologicalProcessaxon development

SCARF1 LRP1 LRP2 LAMA3 LAMB1 LAMC3 KREMEN1 TNC AGRN NOTCH1 NOTCH2

5.07e-106422911GO:0061564
GeneOntologyBiologicalProcessaxon guidance

LRP1 LRP2 LAMA3 LAMB1 LAMC3 AGRN NOTCH1 NOTCH2

4.02e-09285298GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

LRP1 LRP2 LAMA3 LAMB1 LAMC3 AGRN NOTCH1 NOTCH2

4.13e-09286298GO:0097485
GeneOntologyBiologicalProcessaorta development

LRP1 LRP2 NOTCH1 JAG1 NOTCH4

8.54e-0880295GO:0035904
GeneOntologyBiologicalProcesscell-cell adhesion

SCARF1 LAMA3 LAMB1 ITGB7 MEGF11 MEGF10 NOTCH1 JAG1 NOTCH4 CRB1 CELA2A

1.08e-0710772911GO:0098609
GeneOntologyBiologicalProcessartery morphogenesis

LRP1 LRP2 NOTCH1 JAG1 NOTCH4

1.73e-0792295GO:0048844
GeneOntologyBiologicalProcessneuron development

SCARF1 LRP1 LRP2 LAMA3 LAMB1 LAMC3 KREMEN1 TNC AGRN NOTCH1 NOTCH2 CRB1

2.58e-0714632912GO:0048666
GeneOntologyBiologicalProcessregulation of cell adhesion

JAG2 LRP1 LAMA3 LAMB1 TNC MEGF10 NOTCH1 JAG1 NOTCH4 CELA2A

2.94e-079272910GO:0030155
GeneOntologyBiologicalProcessaorta morphogenesis

LRP1 NOTCH1 JAG1 NOTCH4

3.08e-0741294GO:0035909
GeneOntologyBiologicalProcessanimal organ morphogenesis

JAG2 LRP2 LAMA3 LAMB1 LAMC3 TNC MEGF11 NOTCH1 NOTCH2 JAG1 CRB1

5.65e-0712692911GO:0009887
GeneOntologyBiologicalProcessneuron projection development

SCARF1 LRP1 LRP2 LAMA3 LAMB1 LAMC3 KREMEN1 TNC AGRN NOTCH1 NOTCH2

6.41e-0712852911GO:0031175
GeneOntologyBiologicalProcesscell fate determination

JAG2 NOTCH2 JAG1 NOTCH4

6.94e-0750294GO:0001709
GeneOntologyBiologicalProcessaxonogenesis

LRP1 LRP2 LAMA3 LAMB1 LAMC3 AGRN NOTCH1 NOTCH2

7.90e-07566298GO:0007409
GeneOntologyBiologicalProcessartery development

LRP1 LRP2 NOTCH1 JAG1 NOTCH4

1.08e-06133295GO:0060840
GeneOntologyBiologicalProcesscardiac septum development

LRP1 LRP2 NOTCH1 NOTCH2 JAG1

1.12e-06134295GO:0003279
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

JAG2 LRP2 EGF TNC NOTCH1 NOTCH2 JAG1 NOTCH4

1.55e-06619298GO:0002009
GeneOntologyBiologicalProcessgliogenesis

LRP1 LRP2 LAMB1 LAMC3 NOTCH1 NOTCH2 CRB1

1.85e-06435297GO:0042063
GeneOntologyBiologicalProcessaxon regeneration

SCARF1 LRP1 KREMEN1 TNC

2.56e-0669294GO:0031103
GeneOntologyBiologicalProcesspulmonary valve morphogenesis

NOTCH1 NOTCH2 JAG1

2.80e-0620293GO:0003184
GeneOntologyBiologicalProcesscell morphogenesis

LRP1 LRP2 LAMA3 LAMB1 LAMC3 AGRN NOTCH1 NOTCH2 NOTCH4 CRB1

2.96e-0611942910GO:0000902
GeneOntologyBiologicalProcesscamera-type eye morphogenesis

MEGF11 NOTCH1 NOTCH2 JAG1 CRB1

3.73e-06171295GO:0048593
GeneOntologyBiologicalProcesspositive regulation of neural precursor cell proliferation

LRP2 EGF NOTCH1 NOTCH2

4.63e-0680294GO:2000179
GeneOntologyBiologicalProcessneuron projection regeneration

SCARF1 LRP1 KREMEN1 TNC

4.86e-0681294GO:0031102
GeneOntologyBiologicalProcesspulmonary valve development

NOTCH1 NOTCH2 JAG1

4.96e-0624293GO:0003177
GeneOntologyBiologicalProcesscellular response to tumor cell

NOTCH1 NOTCH2

5.72e-063292GO:0071228
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

LRP1 LRP2 LAMA3 LAMB1 LAMC3 AGRN NOTCH1 NOTCH2

6.28e-06748298GO:0048667
GeneOntologyBiologicalProcesstissue morphogenesis

JAG2 LRP2 EGF TNC NOTCH1 NOTCH2 JAG1 NOTCH4

6.41e-06750298GO:0048729
GeneOntologyBiologicalProcesscardiac septum morphogenesis

LRP2 NOTCH1 NOTCH2 JAG1

7.08e-0689294GO:0060411
GeneOntologyBiologicalProcessregulation of muscle cell differentiation

LAMB1 MEGF10 NOTCH1 NOTCH2 NOTCH4

7.82e-06199295GO:0051147
GeneOntologyBiologicalProcesspositive regulation of smooth muscle cell differentiation

NOTCH1 NOTCH2 NOTCH4

7.99e-0628293GO:0051152
GeneOntologyBiologicalProcesseye morphogenesis

MEGF11 NOTCH1 NOTCH2 JAG1 CRB1

8.82e-06204295GO:0048592
GeneOntologyBiologicalProcessNotch signaling pathway

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.02e-05210295GO:0007219
GeneOntologyBiologicalProcessneuron projection morphogenesis

LRP1 LRP2 LAMA3 LAMB1 LAMC3 AGRN NOTCH1 NOTCH2

1.05e-05802298GO:0048812
GeneOntologyBiologicalProcesscardiac chamber development

LRP1 LRP2 NOTCH1 NOTCH2 JAG1

1.06e-05212295GO:0003205
GeneOntologyBiologicalProcesspositive regulation of aorta morphogenesis

NOTCH1 NOTCH4

1.14e-054292GO:1903849
GeneOntologyBiologicalProcessnegative regulation of cell adhesion

LRP1 LAMB1 TNC NOTCH1 JAG1 NOTCH4

1.16e-05375296GO:0007162
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

LRP1 LRP2 LAMA3 LAMB1 LAMC3 AGRN NOTCH1 NOTCH2

1.22e-05819298GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

LRP1 LRP2 LAMA3 LAMB1 LAMC3 AGRN NOTCH1 NOTCH2

1.30e-05826298GO:0048858
GeneOntologyBiologicalProcessresponse to axon injury

SCARF1 LRP1 KREMEN1 TNC

1.37e-05105294GO:0048678
GeneOntologyBiologicalProcesspositive regulation of muscle cell differentiation

LAMB1 NOTCH1 NOTCH2 NOTCH4

1.42e-05106294GO:0051149
GeneOntologyBiologicalProcessregulation of Notch signaling pathway

JAG2 NOTCH1 JAG1 NOTCH4

1.89e-05114294GO:0008593
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LRP1 LRP2

1.90e-055292GO:1905167
GeneOntologyBiologicalProcesschemoattraction of axon

LRP1 LRP2

1.90e-055292GO:0061642
GeneOntologyBiologicalProcesscell-substrate adhesion

LRP1 LAMB1 SNED1 ITGB7 NOTCH1 JAG1

1.92e-05410296GO:0031589
GeneOntologyBiologicalProcessepithelial tube morphogenesis

LRP2 EGF TNC NOTCH1 NOTCH2 NOTCH4

2.23e-05421296GO:0060562
GeneOntologyBiologicalProcesscamera-type eye development

LAMC3 MEGF11 NOTCH1 NOTCH2 JAG1 CRB1

2.38e-05426296GO:0043010
GeneOntologyBiologicalProcessregulation of axon regeneration

SCARF1 LRP1 KREMEN1

2.38e-0540293GO:0048679
GeneOntologyBiologicalProcessregeneration

SCARF1 LRP1 KREMEN1 TNC NOTCH1

2.44e-05252295GO:0031099
GeneOntologyBiologicalProcessresponse to wounding

SCARF1 LRP1 KREMEN1 TNC NOTCH2 NOTCH4 CELA2A

2.78e-05659297GO:0009611
GeneOntologyBiologicalProcessinner ear receptor cell fate commitment

JAG2 NOTCH1

2.85e-056292GO:0060120
GeneOntologyBiologicalProcessregulation of aorta morphogenesis

NOTCH1 NOTCH4

2.85e-056292GO:1903847
GeneOntologyBiologicalProcessciliary body morphogenesis

NOTCH2 JAG1

2.85e-056292GO:0061073
GeneOntologyBiologicalProcesspulmonary artery morphogenesis

LRP2 JAG1

2.85e-056292GO:0061156
GeneOntologyBiologicalProcessauditory receptor cell fate commitment

JAG2 NOTCH1

2.85e-056292GO:0009912
GeneOntologyBiologicalProcessinhibition of neuroepithelial cell differentiation

NOTCH1 JAG1

2.85e-056292GO:0002085
GeneOntologyBiologicalProcessregulation of neural precursor cell proliferation

LRP2 EGF NOTCH1 NOTCH2

3.67e-05135294GO:2000177
GeneOntologyBiologicalProcessapoptotic process involved in development

JAG2 MEGF10 NOTCH1

3.89e-0547293GO:1902742
GeneOntologyBiologicalProcessregulation of neuron projection regeneration

SCARF1 LRP1 KREMEN1

3.89e-0547293GO:0070570
GeneOntologyBiologicalProcessepithelial cell differentiation involved in kidney development

NOTCH1 NOTCH2 JAG1

3.89e-0547293GO:0035850
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process in the vacuole

LRP1 LRP2

3.99e-057292GO:1904352
GeneOntologyBiologicalProcesspositive regulation of transcription of Notch receptor target

NOTCH1 NOTCH4

3.99e-057292GO:0007221
GeneOntologyBiologicalProcesseye development

LAMC3 MEGF11 NOTCH1 NOTCH2 JAG1 CRB1

4.64e-05480296GO:0001654
GeneOntologyBiologicalProcesssemi-lunar valve development

NOTCH1 NOTCH2 JAG1

4.68e-0550293GO:1905314
GeneOntologyBiologicalProcessvisual system development

LAMC3 MEGF11 NOTCH1 NOTCH2 JAG1 CRB1

4.80e-05483296GO:0150063
GeneOntologyBiologicalProcesssensory system development

LAMC3 MEGF11 NOTCH1 NOTCH2 JAG1 CRB1

5.26e-05491296GO:0048880
GeneOntologyBiologicalProcesssensory organ development

JAG2 LAMC3 MEGF11 NOTCH1 NOTCH2 JAG1 CRB1

5.34e-05730297GO:0007423
GeneOntologyBiologicalProcesspositive regulation of Notch signaling pathway

JAG2 NOTCH1 JAG1

5.58e-0553293GO:0045747
GeneOntologyBiologicalProcessregulation of smooth muscle cell differentiation

NOTCH1 NOTCH2 NOTCH4

5.91e-0554293GO:0051150
GeneOntologyBiologicalProcessatrioventricular node development

NOTCH1 NOTCH2

6.83e-059292GO:0003162
GeneOntologyBiologicalProcesspositive regulation of artery morphogenesis

NOTCH1 NOTCH4

6.83e-059292GO:1905653
GeneOntologyBiologicalProcesspositive regulation of cardiac epithelial to mesenchymal transition

NOTCH1 JAG1

6.83e-059292GO:0062043
GeneOntologyBiologicalProcesscell differentiation involved in kidney development

NOTCH1 NOTCH2 JAG1

6.95e-0557293GO:0061005
GeneOntologyBiologicalProcesscardiac chamber morphogenesis

LRP2 NOTCH1 NOTCH2 JAG1

7.29e-05161294GO:0003206
GeneOntologyBiologicalProcessglial cell differentiation

LRP1 LAMC3 NOTCH1 NOTCH2 CRB1

7.73e-05321295GO:0010001
GeneOntologyBiologicalProcesscoronary artery morphogenesis

LRP2 NOTCH1

8.53e-0510292GO:0060982
GeneOntologyBiologicalProcessnegative regulation of cell-cell adhesion mediated by cadherin

NOTCH1 NOTCH4

8.53e-0510292GO:2000048
GeneOntologyBiologicalProcessglomerular epithelial cell development

NOTCH2 JAG1

8.53e-0510292GO:0072310
GeneOntologyBiologicalProcesspodocyte development

NOTCH2 JAG1

8.53e-0510292GO:0072015
GeneOntologyBiologicalProcessdistal tubule development

NOTCH1 JAG1

8.53e-0510292GO:0072017
GeneOntologyBiologicalProcessheart valve morphogenesis

NOTCH1 NOTCH2 JAG1

9.38e-0563293GO:0003179
GeneOntologyBiologicalProcessreceptor-mediated endocytosis

SCARF1 LRP1 LRP2 EGF LRP1B

9.72e-05337295GO:0006898
GeneOntologyBiologicalProcesscell fate commitment

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

9.86e-05338295GO:0045165
GeneOntologyBiologicalProcesssensory organ morphogenesis

MEGF11 NOTCH1 NOTCH2 JAG1 CRB1

1.06e-04343295GO:0090596
GeneOntologyBiologicalProcessblood vessel morphogenesis

LRP1 LRP2 EGF NOTCH1 NOTCH2 JAG1 NOTCH4

1.08e-04817297GO:0048514
GeneOntologyBiologicalProcessinner ear auditory receptor cell differentiation

JAG2 NOTCH1 JAG1

1.13e-0467293GO:0042491
GeneOntologyBiologicalProcessregulation of endothelial cell differentiation

NOTCH1 JAG1 NOTCH4

1.13e-0467293GO:0045601
GeneOntologyBiologicalProcesstube morphogenesis

LRP1 LRP2 EGF TNC NOTCH1 NOTCH2 JAG1 NOTCH4

1.17e-041125298GO:0035239
GeneOntologyBiologicalProcessnegative regulation of epithelial cell differentiation

NOTCH1 JAG1 NOTCH4

1.23e-0469293GO:0030857
GeneOntologyBiologicalProcessepithelium development

JAG2 LRP2 EGF TNC KRT81 NOTCH1 NOTCH2 JAG1 NOTCH4

1.25e-041469299GO:0060429
GeneOntologyBiologicalProcessregulation of lysosomal protein catabolic process

LRP1 LRP2

1.25e-0412292GO:1905165
GeneOntologyBiologicalProcessmuscle structure development

LRP2 LAMB1 MEGF10 NOTCH1 NOTCH2 JAG1 NOTCH4

1.47e-04858297GO:0061061
GeneOntologyBiologicalProcessvenous blood vessel morphogenesis

NOTCH1 NOTCH4

1.47e-0413292GO:0048845
GeneOntologyBiologicalProcessnegative regulation of cell-substrate adhesion

LRP1 NOTCH1 JAG1

1.51e-0474293GO:0010812
GeneOntologyBiologicalProcessmorphogenesis of an epithelial sheet

NOTCH1 NOTCH2 JAG1

1.51e-0474293GO:0002011
GeneOntologyBiologicalProcessbranching morphogenesis of an epithelial tube

EGF TNC NOTCH1 NOTCH4

1.62e-04198294GO:0048754
GeneOntologyBiologicalProcessglomerulus development

NOTCH1 NOTCH2 JAG1

1.70e-0477293GO:0032835
GeneOntologyBiologicalProcessregulation of protein catabolic process in the vacuole

LRP1 LRP2

1.72e-0414292GO:1904350
GeneOntologyBiologicalProcessregulation of cardiac epithelial to mesenchymal transition

NOTCH1 JAG1

1.72e-0414292GO:0062042
GeneOntologyBiologicalProcessleft/right axis specification

NOTCH1 NOTCH2

1.72e-0414292GO:0070986
GeneOntologyBiologicalProcessheart valve development

NOTCH1 NOTCH2 JAG1

1.77e-0478293GO:0003170
GeneOntologyCellularComponentbasement membrane

LAMA3 LAMB1 LAMC3 TNC AGRN

6.62e-07122295GO:0005604
GeneOntologyCellularComponentextracellular matrix

LAMA3 LAMB1 SNED1 LAMC3 MEGF6 TNC AGRN CELA2A

2.16e-06656298GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LAMA3 LAMB1 SNED1 LAMC3 MEGF6 TNC AGRN CELA2A

2.21e-06658298GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LAMA3 LAMB1 LAMC3 MEGF6 TNC AGRN CELA2A

6.22e-06530297GO:0062023
GeneOntologyCellularComponentendocytic vesicle membrane

SCARF1 LRP1 LRP2 TYRP1 EGF

9.97e-06212295GO:0030666
GeneOntologyCellularComponentaxonal growth cone

LRP1 LRP2 AGRN

3.28e-0545293GO:0044295
GeneOntologyCellularComponentprotein complex involved in cell adhesion

LAMB1 TNC ITGB7

7.41e-0559293GO:0098636
GeneOntologyCellularComponentlaminin complex

LAMA3 LAMB1

8.30e-0510292GO:0043256
GeneOntologyCellularComponentreceptor complex

LRP1 LRP2 LRP1B ITGB7 NOTCH1 NOTCH2

1.24e-04581296GO:0043235
GeneOntologyCellularComponentendocytic vesicle

SCARF1 LRP1 LRP2 TYRP1 EGF

1.68e-04384295GO:0030139
GeneOntologyCellularComponentclathrin-coated endocytic vesicle membrane

LRP2 TYRP1 EGF

1.77e-0479293GO:0030669
GeneOntologyCellularComponentadherens junction

LAMA3 NOTCH1 JAG1 CRB1

2.00e-04212294GO:0005912
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMB1 TNC

2.49e-0417292GO:0098637
GeneOntologyCellularComponentanchoring junction

LRP1 LAMA3 TNC ITGB7 NOTCH1 JAG1 CRB1

2.99e-04976297GO:0070161
GeneOntologyCellularComponentclathrin-coated vesicle

LRP1 LRP2 TYRP1 EGF

3.06e-04237294GO:0030136
GeneOntologyCellularComponentclathrin-coated endocytic vesicle

LRP2 TYRP1 EGF

3.65e-04101293GO:0045334
GeneOntologyCellularComponentcell surface

LRP1 LRP2 AGRN ITGB7 NOTCH1 NOTCH2 NOTCH4

6.54e-041111297GO:0009986
GeneOntologyCellularComponentclathrin-coated vesicle membrane

LRP2 TYRP1 EGF

1.09e-03147293GO:0030665
GeneOntologyCellularComponentapical part of cell

LRP1 LRP2 NOTCH1 JAG1 CRB1

1.21e-03592295GO:0045177
GeneOntologyCellularComponentcoated vesicle

LRP1 LRP2 TYRP1 EGF

1.46e-03360294GO:0030135
GeneOntologyCellularComponentcell-substrate junction

LRP1 LAMA3 TNC ITGB7

3.11e-03443294GO:0030055
GeneOntologyCellularComponentcoated vesicle membrane

LRP2 TYRP1 EGF

3.22e-03215293GO:0030662
GeneOntologyCellularComponentapical plasma membrane

LRP2 NOTCH1 JAG1 CRB1

4.35e-03487294GO:0016324
GeneOntologyCellularComponentgrowth cone

LRP1 LRP2 AGRN

4.64e-03245293GO:0030426
GeneOntologyCellularComponentsite of polarized growth

LRP1 LRP2 AGRN

5.07e-03253293GO:0030427
GeneOntologyCellularComponentclathrin-coated pit

LRP1 LRP2

5.49e-0380292GO:0005905
GeneOntologyCellularComponentcytoplasmic vesicle membrane

SCARF1 LRP1 LRP2 TYRP1 EGF NOTCH1

8.09e-031307296GO:0030659
GeneOntologyCellularComponentcell-cell junction

LAMA3 NOTCH1 JAG1 CRB1

8.57e-03591294GO:0005911
GeneOntologyCellularComponentvesicle membrane

SCARF1 LRP1 LRP2 TYRP1 EGF NOTCH1

8.64e-031325296GO:0012506
MousePhenoincreased cochlear hair cell number

JAG2 NOTCH1 JAG1

8.02e-0620283MP:0004407
MousePhenoabnormal sensory neuron morphology

JAG2 LAMC3 MEGF11 MEGF10 NOTCH1 JAG1 CRB1

3.10e-05473287MP:0000965
MousePhenoincreased sensory neuron number

JAG2 NOTCH1 JAG1

7.29e-0541283MP:0006006
MousePhenoabnormal cochlear labyrinth morphology

JAG2 LRP2 TYRP1 NOTCH1 JAG1

9.22e-05235285MP:0004426
MousePhenoabnormal scala media morphology

JAG2 LRP2 TYRP1 NOTCH1 JAG1

9.22e-05235285MP:0003169
MousePhenoabnormal cochlea morphology

JAG2 LRP2 TYRP1 NOTCH1 JAG1

1.19e-04248285MP:0000031
MousePhenoabnormal cochlear outer hair cell number

JAG2 NOTCH1 JAG1

1.32e-0450283MP:0004400
MousePhenoabnormal membranous labyrinth morphology

JAG2 LRP2 TYRP1 NOTCH1 JAG1

1.54e-04262285MP:0000035
MousePhenoabnormal inner ear morphology

JAG2 LRP2 TYRP1 NOTCH1 JAG1

3.02e-04303285MP:0000026
MousePhenoabnormal cochlear hair cell number

JAG2 NOTCH1 JAG1

3.31e-0468283MP:0004406
MousePhenoincreased cochlear inner hair cell number

JAG2 JAG1

3.47e-0414282MP:0004395
MousePhenoabnormal somatic sensory system morphology

JAG2 LAMC3 MEGF11 MEGF10 NOTCH1 JAG1 CRB1

3.66e-04702287MP:0000959
MousePhenoincreased neuron number

JAG2 NOTCH1 JAG1

3.91e-0472283MP:0008947
MousePhenoabnormal bile duct development

NOTCH2 JAG1

4.00e-0415282MP:0002929
MousePhenoincreased cochlear outer hair cell number

JAG2 NOTCH1

4.56e-0416282MP:0004401
MousePhenoabnormal retina horizontal cell morphology

MEGF11 MEGF10

6.48e-0419282MP:0006068
MousePhenoabnormal somatic nervous system morphology

JAG2 LAMC3 AGRN MEGF11 MEGF10 NOTCH1 JAG1 CRB1

6.72e-041025288MP:0002752
DomainEGF_1

SCARF1 JAG2 LRP1 LRP2 LAMA3 CRELD2 LAMB1 SNED1 LAMC3 OIT3 EGF MEGF6 ADAM23 LRP1B TNC AGRN ITGB7 MEGF11 ATRNL1 MEGF10 NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

1.64e-432552925PS00022
DomainEGF_2

SCARF1 JAG2 LRP1 LRP2 LAMA3 CRELD2 LAMB1 SNED1 LAMC3 OIT3 EGF MEGF6 ADAM23 LRP1B TNC AGRN ITGB7 MEGF11 ATRNL1 MEGF10 NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

4.49e-432652925PS01186
DomainEGF

SCARF1 JAG2 LRP1 LRP2 LAMA3 CRELD2 LAMB1 SNED1 LAMC3 OIT3 EGF MEGF6 ADAM23 LRP1B TNC AGRN MEGF11 ATRNL1 MEGF10 NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

8.39e-422352924SM00181
DomainEGF-like_dom

SCARF1 JAG2 LRP1 LRP2 LAMA3 CRELD2 LAMB1 SNED1 LAMC3 OIT3 EGF MEGF6 ADAM23 LRP1B TNC AGRN MEGF11 ATRNL1 MEGF10 NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

3.60e-412492924IPR000742
DomainEGF-like_CS

SCARF1 JAG2 LRP1 LRP2 LAMA3 CRELD2 LAMB1 SNED1 LAMC3 EGF MEGF6 ADAM23 LRP1B TNC AGRN ITGB7 MEGF11 ATRNL1 MEGF10 NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

1.17e-402612924IPR013032
DomainEGF_3

SCARF1 JAG2 LRP1 LRP2 CRELD2 SNED1 OIT3 EGF MEGF6 ADAM23 LRP1B TNC AGRN MEGF11 ATRNL1 MEGF10 NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

1.97e-342352921PS50026
DomainGrowth_fac_rcpt_

SCARF1 JAG2 LRP1 LRP2 LAMA3 CRELD2 LAMB1 LAMC3 EGF MEGF6 LRP1B TNC NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

9.11e-291562917IPR009030
DomainEGF_CA

JAG2 LRP1 LRP2 CRELD2 SNED1 OIT3 EGF MEGF6 LRP1B AGRN NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

4.96e-261222915SM00179
DomainEGF_extracell

SCARF1 JAG2 LRP2 MEGF6 ADAM23 LRP1B TNC ITGB7 MEGF11 ATRNL1 MEGF10 NOTCH1 JAG1

6.28e-26602913IPR013111
DomainEGF_2

SCARF1 JAG2 LRP2 MEGF6 ADAM23 LRP1B TNC ITGB7 MEGF11 ATRNL1 MEGF10 NOTCH1 JAG1

6.28e-26602913PF07974
DomainEGF-like_Ca-bd_dom

JAG2 LRP1 LRP2 CRELD2 SNED1 OIT3 EGF MEGF6 LRP1B AGRN NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

6.42e-261242915IPR001881
DomainEGF_Ca-bd_CS

JAG2 LRP1 LRP2 CRELD2 SNED1 OIT3 EGF MEGF6 LRP1B NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

2.84e-25972914IPR018097
DomainEGF_CA

JAG2 LRP1 LRP2 CRELD2 SNED1 OIT3 EGF MEGF6 LRP1B NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

3.85e-25992914PS01187
DomainASX_HYDROXYL

JAG2 LRP1 LRP2 CRELD2 SNED1 OIT3 EGF MEGF6 LRP1B NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

4.48e-251002914PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

JAG2 LRP1 LRP2 CRELD2 SNED1 OIT3 EGF MEGF6 LRP1B NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

1.07e-241062914IPR000152
DomainEGF

JAG2 LRP1 LRP2 SNED1 EGF MEGF6 LRP1B TNC AGRN NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

1.37e-231262914PF00008
DomainhEGF

JAG2 SNED1 MEGF6 MEGF11 MEGF10 NOTCH1 NOTCH2 JAG1 NOTCH4 CRB1

1.82e-22282910PF12661
DomainLaminin_EGF

SCARF1 LAMA3 CRELD2 LAMB1 LAMC3 MEGF6 AGRN MEGF11 ATRNL1 MEGF10

6.50e-21382910IPR002049
DomainEGF_CA

JAG2 LRP1 LRP2 CRELD2 EGF MEGF6 LRP1B NOTCH1 NOTCH2 JAG1 NOTCH4

3.29e-19862911PF07645
DomainLaminin_EGF

SCARF1 LAMA3 LAMB1 LAMC3 MEGF6 AGRN MEGF11 MEGF10

2.68e-1635298PF00053
DomainEGF_Lam

LAMA3 LAMB1 LAMC3 MEGF6 AGRN MEGF11 ATRNL1 MEGF10

2.68e-1635298SM00180
DomainEGF_LAM_2

LAMA3 LAMB1 LAMC3 AGRN ATRNL1

8.70e-1030295PS50027
DomainEGF_LAM_1

LAMA3 LAMB1 LAMC3 AGRN ATRNL1

8.70e-1030295PS01248
DomainLdl_recept_b

LRP1 LRP2 EGF LRP1B

4.64e-0914294PF00058
DomainLDLRB

LRP1 LRP2 EGF LRP1B

4.64e-0914294PS51120
DomainLY

LRP1 LRP2 EGF LRP1B

6.32e-0915294SM00135
DomainLDLR_classB_rpt

LRP1 LRP2 EGF LRP1B

6.32e-0915294IPR000033
DomainNOD

NOTCH1 NOTCH2 NOTCH4

1.34e-084293PF06816
DomainNotch

NOTCH1 NOTCH2 NOTCH4

1.34e-084293IPR008297
DomainNODP

NOTCH1 NOTCH2 NOTCH4

1.34e-084293PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH2 NOTCH4

1.34e-084293IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH2 NOTCH4

1.34e-084293IPR010660
DomainNOD

NOTCH1 NOTCH2 NOTCH4

1.34e-084293SM01338
DomainNODP

NOTCH1 NOTCH2 NOTCH4

1.34e-084293SM01339
DomainLNR

NOTCH1 NOTCH2 NOTCH4

3.36e-085293PS50258
DomainNotch_dom

NOTCH1 NOTCH2 NOTCH4

1.17e-077293IPR000800
DomainNotch

NOTCH1 NOTCH2 NOTCH4

1.17e-077293PF00066
DomainNL

NOTCH1 NOTCH2 NOTCH4

1.17e-077293SM00004
Domain-

LRP1 LRP2 EGF LRP1B

3.71e-07392942.120.10.30
Domain6-blade_b-propeller_TolB-like

LRP1 LRP2 EGF LRP1B

7.31e-0746294IPR011042
DomainLAMININ_NTER

LAMA3 LAMB1 LAMC3

1.86e-0616293PS51117
DomainLaminin_N

LAMA3 LAMB1 LAMC3

1.86e-0616293PF00055
DomainEMI_domain

MEGF6 MEGF11 MEGF10

1.86e-0616293IPR011489
DomainLaminin_N

LAMA3 LAMB1 LAMC3

1.86e-0616293IPR008211
DomainLamNT

LAMA3 LAMB1 LAMC3

1.86e-0616293SM00136
DomainEMI

MEGF6 MEGF11 MEGF10

2.26e-0617293PS51041
DomainDUF5050

LRP1 LRP1B

2.33e-062292IPR032485
DomainDUF5050

LRP1 LRP1B

2.33e-062292PF16472
DomainJagged/Serrate

JAG2 JAG1

2.33e-062292IPR026219
DomainDUF3454

NOTCH1 NOTCH2

6.98e-063292PF11936
DomainDUF3454_notch

NOTCH1 NOTCH2

6.98e-063292IPR024600
DomainDUF3454

NOTCH1 NOTCH2

6.98e-063292SM01334
DomaincEGF

LRP1 LRP2 LRP1B

8.54e-0626293IPR026823
DomaincEGF

LRP1 LRP2 LRP1B

8.54e-0626293PF12662
DomainDSL

JAG2 JAG1

1.39e-054292PF01414
DomainDSL

JAG2 JAG1

1.39e-054292SM00051
DomainDSL

JAG2 JAG1

2.32e-055292IPR001774
DomainDSL

JAG2 JAG1

2.32e-055292PS51051
DomainNotch_ligand_N

JAG2 JAG1

2.32e-055292IPR011651
DomainMNNL

JAG2 JAG1

2.32e-055292PF07657
DomainLAM_G_DOMAIN

LAMA3 AGRN CRB1

2.74e-0538293PS50025
DomainLDLR_class-A_CS

LRP1 LRP2 LRP1B

3.20e-0540293IPR023415
DomainLamG

LAMA3 AGRN CRB1

4.27e-0544293SM00282
DomainLdl_recept_a

LRP1 LRP2 LRP1B

4.57e-0545293PF00057
Domain-

LRP1 LRP2 LRP1B

4.88e-05462934.10.400.10
DomainLDLRA_1

LRP1 LRP2 LRP1B

5.55e-0548293PS01209
DomainLDrepeatLR_classA_rpt

LRP1 LRP2 LRP1B

5.91e-0549293IPR002172
DomainLDLa

LRP1 LRP2 LRP1B

5.91e-0549293SM00192
DomainLDLRA_2

LRP1 LRP2 LRP1B

5.91e-0549293PS50068
DomainLAMININ_IVA

LAMA3 LAMC3

6.48e-058292PS51115
DomainLaminin_B

LAMA3 LAMC3

6.48e-058292PF00052
DomainLamB

LAMA3 LAMC3

6.48e-058292SM00281
DomainLaminin_IV

LAMA3 LAMC3

6.48e-058292IPR000034
DomainLaminin_G

LAMA3 AGRN CRB1

9.81e-0558293IPR001791
DomainFol_N

SNED1 AGRN

1.27e-0411292IPR003645
DomainFOLN

SNED1 AGRN

1.27e-0411292SM00274
DomainVWC_out

JAG2 JAG1

3.92e-0419292SM00215
Domain-

LAMA3 AGRN CRB1

4.23e-04952932.60.120.200
DomainVWC

JAG2 JAG1

1.58e-0338292SM00214
DomainLaminin_G_2

LAMA3 CRB1

1.75e-0340292PF02210
DomainVWF_dom

JAG2 JAG1

1.93e-0342292IPR001007
DomainPSI

ITGB7 ATRNL1

2.11e-0344292IPR016201
DomainPSI

ITGB7 ATRNL1

2.31e-0346292SM00423
DomainCUB

KREMEN1 ATRNL1

2.62e-0349292PF00431
DomainCUB

KREMEN1 ATRNL1

2.72e-0350292SM00042
Domain-

KREMEN1 ATRNL1

2.94e-03522922.60.120.290
DomainCUB

KREMEN1 ATRNL1

3.05e-0353292PS01180
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.17e-1113245M47423
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

7.22e-1027245M39545
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 NOTCH2 JAG1 NOTCH4

3.17e-0912244M47532
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

JAG2 EGF NOTCH1 NOTCH2 JAG1 NOTCH4

3.98e-0982246MM15922
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMA3 LAMB1 LAMC3 TNC AGRN ITGB7

4.61e-0984246M7098
PathwayREACTOME_SIGNALING_BY_NOTCH

JAG2 EGF NOTCH1 JAG1 NOTCH4

5.08e-0939245MM14604
PathwayWP_NOTCH_SIGNALING_WP268

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.07e-0845245M39571
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 JAG1 NOTCH4

1.16e-0816244M47424
PathwayWP_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.20e-0846245MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.34e-0847245M7946
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMA3 LAMB1 LAMC3 TNC AGRN

4.32e-0859245M27218
PathwayPID_NOTCH_PATHWAY

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

4.32e-0859245M17
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH2 NOTCH4

4.33e-085243M27411
PathwayWP_NOTCH_SIGNALING_WP61

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

5.12e-0861245M39540
PathwayWP_CANCER_PATHWAYS

JAG2 LAMA3 LAMB1 LAMC3 EGF NOTCH1 NOTCH2 JAG1 NOTCH4

7.57e-08507249M48302
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH2 NOTCH4

8.64e-086243M27068
PathwayREACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT

JAG2 NOTCH1 JAG1

1.51e-077243M27199
PathwayWP_FOCAL_ADHESION

LAMA3 LAMB1 LAMC3 EGF TNC ITGB7

5.55e-07187246MM15913
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH2 NOTCH4

7.09e-0711243M47865
PathwayWP_FOCAL_ADHESION

LAMA3 LAMB1 LAMC3 EGF TNC ITGB7

7.99e-07199246M39402
PathwayKEGG_FOCAL_ADHESION

LAMA3 LAMB1 LAMC3 EGF TNC ITGB7

7.99e-07199246M7253
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH2 NOTCH4

9.44e-0712243M47533
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

LAMA3 LAMB1 LAMC3 EGF

1.01e-0646244M239
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH1 NOTCH2 NOTCH4

1.23e-0613243M47534
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG2 EGF NOTCH1 JAG1

1.30e-0649244M618
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.41e-06118245M39852
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

JAG2 NOTCH1 JAG1

1.95e-0615243M27202
PathwayREACTOME_SIGNALING_BY_NOTCH

JAG2 EGF NOTCH1 NOTCH2 JAG1 NOTCH4

2.75e-06246246M10189
PathwayWP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS

TNC NOTCH1 JAG1

2.90e-0617243M39443
PathwayWP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION

JAG2 NOTCH1 JAG1

2.90e-0617243M39389
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH2 NOTCH4

3.48e-0618243M614
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG2 EGF JAG1

4.13e-0619243MM15594
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH2 NOTCH4

4.85e-0620243M27881
PathwayWP_BREAST_CANCER_PATHWAY

JAG2 EGF NOTCH1 NOTCH2 NOTCH4

5.24e-06154245M39739
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

6.51e-06161245M39770
PathwayREACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

JAG2 NOTCH2 JAG1

6.54e-0622243M27210
PathwayREACTOME_ECM_PROTEOGLYCANS

LAMA3 LAMB1 TNC AGRN

7.64e-0676244M27219
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

NOTCH1 NOTCH2 NOTCH4

8.57e-0624243M11190
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LAMA3 LAMB1 LAMC3 TNC AGRN ITGB7

8.61e-06300246M610
PathwayWP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING

LAMA3 LAMB1 LAMC3 EGF TNC ITGB7

8.94e-06302246M39719
PathwayREACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

JAG2 EGF JAG1

9.73e-0625243M27879
PathwayREACTOME_SIGNALING_BY_NOTCH4

NOTCH1 NOTCH2 JAG1 NOTCH4

1.03e-0582244M594
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH2 NOTCH4

1.38e-0528243M6177
PathwayWP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY

LAMA3 LAMB1 LAMC3 EGF TNC ITGB7

1.38e-05326246MM15917
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMA3 LAMB1 LAMC3

1.71e-0530243M27772
PathwayREACTOME_LAMININ_INTERACTIONS

LAMA3 LAMB1 LAMC3

1.71e-0530243M27216
PathwayWP_PI3KAKT_SIGNALING

LAMA3 LAMB1 LAMC3 EGF TNC ITGB7

1.73e-05339246M39736
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

JAG2 NOTCH1 JAG1

1.89e-0531243M592
PathwayREACTOME_SIGNALING_BY_NOTCH2

JAG2 NOTCH2 JAG1

2.29e-0533243M604
PathwayWP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT

NOTCH1 NOTCH2 NOTCH4

2.51e-0534243M39390
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH4

2.77e-055242MM14733
PathwayWP_NEOVASCULARIZATION_PROCESSES

NOTCH1 JAG1 NOTCH4

3.24e-0537243M39506
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMA3 LAMB1 LAMC3

4.43e-0541243M27778
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH4

5.80e-057242MM14734
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP1 LRP2 AGRN

5.87e-0545243MM15344
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP1 LRP2 AGRN

7.13e-0548243M27642
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

AGRN NOTCH1 NOTCH2 NOTCH4

9.21e-05143244M27275
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION

JAG2 JAG1

9.93e-059242M47866
PathwayWP_NEUROGENESIS_REGULATION_IN_THE_OLFACTORY_EPITHELIUM

AGRN NOTCH1 JAG1

1.19e-0457243M48326
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

JAG2 NOTCH1

1.24e-0410242MM14849
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

JAG2 NOTCH1 JAG1

1.26e-0458243M29616
PathwayWP_MARKERS_OF_KIDNEY_CELL_LINEAGE

TNC NOTCH1 JAG1

1.32e-0459243M46460
PathwayREACTOME_NOTCH4_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

JAG1 NOTCH4

1.51e-0411242M27882
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

EGF NOTCH1

1.51e-0411242M48021
PathwayPID_INTEGRIN4_PATHWAY

LAMA3 LAMB1

1.51e-0411242M158
PathwayBIOCARTA_HES_PATHWAY

NOTCH1 NOTCH2

1.81e-0412242MM1562
PathwayBIOCARTA_HES_PATHWAY

NOTCH1 NOTCH2

1.81e-0412242M22042
PathwayPID_INTEGRIN1_PATHWAY

LAMA3 LAMB1 TNC

1.85e-0466243M18
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

NOTCH1 NOTCH2 NOTCH4

2.02e-0468243M27303
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

AGRN NOTCH1 JAG1

2.39e-0472243M39403
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

AGRN NOTCH1 JAG1

2.49e-0473243MM15906
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

NOTCH1 JAG1

2.50e-0414242M27808
PathwayREACTOME_SIGNALING_BY_NOTCH1

JAG2 NOTCH1 JAG1

2.60e-0474243M616
PathwayREACTOME_SIGNALING_BY_MET

LAMA3 LAMB1 LAMC3

3.15e-0479243M27643
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

LAMB1 TYRP1 EGF ADAM23 AGRN KRT81 NOTCH1 JAG1 CELA2A

3.56e-041432249M509
PathwayKEGG_SMALL_CELL_LUNG_CANCER

LAMA3 LAMB1 LAMC3

3.77e-0484243M3228
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

TNC AGRN ITGB7

3.91e-0485243M16441
PathwayWP_NEPHROGENESIS

NOTCH2 JAG1

4.18e-0418242M40045
PathwayREACTOME_SIGNALING_BY_NOTCH1

JAG2 NOTCH1

4.18e-0418242MM14775
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

LRP1 LRP2 AGRN

4.93e-0492243MM14881
PathwayWP_SMALL_CELL_LUNG_CANCER

LAMA3 LAMB1 LAMC3

5.58e-0496243M39834
PathwayWP_NEURAL_CREST_DIFFERENTIATION

NOTCH1 NOTCH2 NOTCH4

5.76e-0497243MM15926
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

LRP1 LRP2 AGRN

6.29e-04100243M27158
PathwayWP_NEURAL_CREST_DIFFERENTIATION

NOTCH1 NOTCH2 NOTCH4

6.48e-04101243M39448
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH4

6.88e-0423242MM14954
PathwayWP_PLEURAL_MESOTHELIOMA

LAMA3 LAMB1 LAMC3 KREMEN1 EGF

7.45e-04439245M42563
PathwayREACTOME_DISEASES_OF_METABOLISM

AGRN NOTCH1 NOTCH2 NOTCH4

7.76e-04250244M27554
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

MEGF6 TNC AGRN ITGB7

8.73e-04258244MM14572
PathwayREACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

JAG2 KREMEN1 EGF NOTCH1 JAG1

9.57e-04464245M27547
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH2 NOTCH4

1.04e-03119243M607
PathwayBIOCARTA_AGR_PATHWAY

LAMA3 AGRN

1.25e-0331242MM1343
PathwayPID_SYNDECAN_4_PATHWAY

LAMA3 TNC

1.34e-0332242M165
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMA3 LAMB1

1.42e-0333242M39503
PathwayBIOCARTA_AGR_PATHWAY

LAMA3 AGRN

1.42e-0333242M6220
PathwayWP_GENETIC_CAUSES_OF_PORTOSINUSOIDAL_VASCULAR_DISEASE

NOTCH1 NOTCH4

1.78e-0337242M45513
PathwayKEGG_PATHWAYS_IN_CANCER

LAMA3 LAMB1 LAMC3 EGF

2.05e-03325244M12868
PathwayPID_INTEGRIN3_PATHWAY

LAMB1 TNC

2.40e-0343242M53
PathwayREACTOME_ECM_PROTEOGLYCANS

TNC AGRN

2.87e-0347242MM14925
PathwayWP_PLURIPOTENT_STEM_CELL_DIFFERENTIATION_PATHWAY

EGF NOTCH1

2.99e-0348242M39427
PathwayREACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS

LRP1 LRP2 AGRN

3.90e-03189243MM14772
Pubmed

Human ligands of the Notch receptor.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

5.88e-15729510079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

5.88e-15729512846471
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.57e-1482959858718
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

3.52e-14929511118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

3.52e-14929516245338
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

7.04e-141029523665443
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.29e-131129510878608
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.29e-131129512866128
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

2.21e-131229515465494
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

3.59e-131329511578869
Pubmed

Notch pathway regulates female germ cell meiosis progression and early oogenesis events in fetal mouse.

JAG2 NOTCH1 NOTCH2 JAG1

3.90e-13429424398584
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

5.58e-131429514757642
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

8.36e-131529512971992
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.22e-121629512617809
Pubmed

Notch gene expression during pancreatic organogenesis.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.22e-121629510842072
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.22e-121629517273555
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.72e-121729518694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.72e-121729515821257
Pubmed

Functional diversity of notch family genes in fetal lung development.

JAG2 NOTCH1 NOTCH2 JAG1

1.95e-12529415064243
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH1 NOTCH2 JAG1 NOTCH4

1.95e-12529415882997
Pubmed

Association of Notch pathway down-regulation with Triple Negative/Basal-like breast carcinomas and high tumor-infiltrating FOXP3+ Tregs.

NOTCH1 NOTCH2 JAG1 NOTCH4

1.95e-12529427118257
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

2.38e-121829518093989
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

2.38e-121829515689374
Pubmed

Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

3.23e-121929516518823
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

5.65e-122129528656980
Pubmed

Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

5.65e-122129514702043
Pubmed

Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2.

JAG2 NOTCH1 NOTCH2 JAG1

5.84e-12629410958687
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH1 NOTCH2 JAG1 NOTCH4

5.84e-12629412244553
Pubmed

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

9.33e-122329514701881
Pubmed

Rbpj regulates development of prosensory cells in the mammalian inner ear.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.18e-112429521420948
Pubmed

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.

JAG2 NOTCH1 NOTCH2 JAG1

1.36e-11729410383933
Pubmed

Notch signaling controls liver development by regulating biliary differentiation.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.82e-112629519369401
Pubmed

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

NOTCH1 NOTCH2 JAG1 NOTCH4

2.72e-11829422156581
Pubmed

P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis.

JAG2 NOTCH1 NOTCH2 JAG1

2.72e-11829422652674
Pubmed

Notch1 and Jagged1 expression by the developing pulmonary vasculature.

NOTCH1 NOTCH2 JAG1 NOTCH4

2.72e-11829412242716
Pubmed

Notch/Delta expression in the developing mouse lung.

JAG2 NOTCH1 NOTCH2 JAG1

2.72e-11829411044610
Pubmed

Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

3.28e-112929525535917
Pubmed

Notch signaling in stomach epithelial stem cell homeostasis.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

3.28e-112929521402740
Pubmed

Notch signaling regulates ovarian follicle formation and coordinates follicular growth.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

3.94e-113029524552588
Pubmed

ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

4.69e-113129537573008
Pubmed

Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad.

JAG2 NOTCH1 JAG1 NOTCH4

4.90e-11929411944948
Pubmed

Notch signaling is essential for vascular morphogenesis in mice.

JAG2 NOTCH1 JAG1 NOTCH4

4.90e-11929410837027
Pubmed

Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

7.67e-113429521311046
Pubmed

Notch signaling regulates smooth muscle differentiation of epicardium-derived cells.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

8.94e-113529521252157
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

LAMA3 CRELD2 LAMB1 MEGF6 TNC AGRN CELA2A

1.03e-1017529728071719
Pubmed

Notch signaling in postnatal pituitary expansion: proliferation, progenitors, and cell specification.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.20e-103729524673559
Pubmed

Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

1.20e-103729527631609
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

JAG2 NOTCH1 NOTCH2 NOTCH4

1.28e-101129416607638
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

NOTCH1 NOTCH2 JAG1 NOTCH4

1.28e-101129415499562
Pubmed

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

NOTCH1 NOTCH2 JAG1 NOTCH4

1.28e-10112949187150
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

2.06e-104129522675208
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

LRP1 LRP2 LRP1B ITGB7 NOTCH1 NOTCH2

2.32e-1010129623382219
Pubmed

Jagged1 is Essential for Radial Glial Maintenance in the Cortical Proliferative Zone.

JAG2 NOTCH1 NOTCH2 JAG1

2.77e-101329431202705
Pubmed

Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.

NOTCH1 NOTCH2 JAG1 NOTCH4

2.77e-101329420558824
Pubmed

The notch pathway positively regulates programmed cell death during erythroid differentiation.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

2.97e-104429517476283
Pubmed

Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1.

JAG2 NOTCH1 JAG1 NOTCH4

3.88e-101429418528438
Pubmed

Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis.

JAG2 NOTCH1 JAG1 NOTCH4

3.88e-101429428192800
Pubmed

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia.

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

4.68e-104829535247391
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

JAG2 CRELD2 MEGF6 TNC AGRN MEGF11 MEGF10 NOTCH1 NOTCH2

5.13e-1056029921653829
Pubmed

Notch signaling drives multiple myeloma induced osteoclastogenesis.

JAG2 NOTCH2 JAG1

5.21e-10329325257302
Pubmed

Characterization of Notch Signalling Pathway Members in Normal Prostate, Prostatic Intraepithelial Neoplasia (PIN) and Prostatic Adenocarcinoma.

NOTCH1 JAG1 NOTCH4

5.21e-10329326341090
Pubmed

Differential expression of Notch genes in human osteoblastic cells.

NOTCH1 NOTCH2 NOTCH4

5.21e-10329311836628
Pubmed

Dendritic cell-mediated NK cell activation is controlled by Jagged2-Notch interaction.

JAG2 NOTCH1 NOTCH2

5.21e-10329318458347
Pubmed

Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation.

NOTCH1 JAG1 NOTCH4

5.21e-10329314988227
Pubmed

Unique patterns of Notch1, Notch4 and Jagged1 expression in ovarian vessels during folliculogenesis and corpus luteum formation.

NOTCH1 JAG1 NOTCH4

5.21e-10329315939383
Pubmed

Notch signaling: cell fate control and signal integration in development.

NOTCH1 NOTCH2 NOTCH4

5.21e-10329310221902
Pubmed

The Notch-mediated circuitry in the evolution and generation of new cell lineages: the tooth model.

JAG2 NOTCH1 NOTCH2

5.21e-10329337330998
Pubmed

Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells.

NOTCH1 NOTCH2 JAG1

5.21e-10329314726396
Pubmed

Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth.

JAG2 NOTCH1 NOTCH2 JAG1

5.29e-101529412167404
Pubmed

COUP-TFI controls Notch regulation of hair cell and support cell differentiation.

JAG2 NOTCH1 NOTCH2 JAG1

5.29e-101529416914494
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

JAG2 LRP1 LAMB1 MEGF6 AGRN NOTCH1

5.98e-1011829621078624
Pubmed

The Cellular Prion Protein Controls Notch Signaling in Neural Stem/Progenitor Cells.

JAG2 NOTCH1 NOTCH2 JAG1

7.04e-101629427641601
Pubmed

Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice.

JAG2 NOTCH1 NOTCH2 JAG1

7.04e-101629432161758
Pubmed

Notch Signaling Pathway in Tooth Shape Variations throughout Evolution.

JAG2 NOTCH1 NOTCH2 JAG1

1.18e-091829436899896
Pubmed

Six1 is indispensable for production of functional progenitor cells during olfactory epithelial development.

JAG2 NOTCH1 NOTCH2 JAG1

1.50e-091929421302255
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH1 NOTCH2 NOTCH4

2.08e-09429328061457
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH1 NOTCH2 NOTCH4

2.08e-09429324145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH1 NOTCH2 NOTCH4

2.08e-09429320069356
Pubmed

A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea.

JAG2 NOTCH1 JAG1

2.08e-09429310837254
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH1 NOTCH2 NOTCH4

2.08e-09429319404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH1 NOTCH2 NOTCH4

2.08e-09429328669409
Pubmed

Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes.

NOTCH1 NOTCH2 JAG1

2.08e-09429322390640
Pubmed

Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming.

NOTCH1 NOTCH2 JAG1

2.08e-09429330226866
Pubmed

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.

NOTCH1 NOTCH2 JAG1

2.08e-09429310551863
Pubmed

Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor.

JAG2 NOTCH1 JAG1

2.08e-0942939315665
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH1 NOTCH2 NOTCH4

2.08e-09429311466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH1 NOTCH2 NOTCH4

2.08e-09429324151014
Pubmed

Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin.

NOTCH1 JAG1 NOTCH4

2.08e-09429317984306
Pubmed

Activation of Notch signaling in human tongue carcinoma.

JAG2 NOTCH1 JAG1

2.08e-09429320819128
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH1 NOTCH2 NOTCH4

2.08e-09429311401408
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH1 NOTCH2 NOTCH4

2.08e-09429310194420
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH1 NOTCH2 NOTCH4

2.08e-0942938898100
Pubmed

Notch1 and Notch4 core binding domain peptibodies exhibit distinct ligand-binding and anti-angiogenic properties.

NOTCH1 JAG1 NOTCH4

2.08e-09429336376768
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH1 NOTCH2 NOTCH4

2.08e-09429311459941
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH1 NOTCH2 NOTCH4

2.08e-09429318184405
Pubmed

Detection of Notch signaling molecules in cemento-ossifying fibroma of the jaws.

JAG2 NOTCH1 JAG1

2.08e-09429320040020
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH1 NOTCH2 NOTCH4

2.08e-09429315917835
Pubmed

The Notch signalling pathway in hair growth.

JAG2 NOTCH1 JAG1

2.08e-0942939858728
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH1 NOTCH2 NOTCH4

2.08e-09429323444212
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH1 NOTCH2 NOTCH4

2.08e-09429317920003
InteractionIGFL3 interactions

JAG2 LRP2 LAMA3 LAMB1 LRP1B AGRN NOTCH1 NOTCH2

1.01e-1375298int:IGFL3
InteractionFBXO2 interactions

JAG2 LRP2 LAMA3 LAMB1 SNED1 LAMC3 ADAM23 LRP1B AGRN NOTCH1 NOTCH2 JAG1

1.67e-134112912int:FBXO2
InteractionZFP41 interactions

LRP1 LRP2 CRELD2 LRP1B AGRN NOTCH2

1.76e-1057296int:ZFP41
InteractionNTN5 interactions

JAG2 LRP2 LRP1B NOTCH1 NOTCH2

1.79e-1024295int:NTN5
InteractionCACNA1A interactions

JAG2 LRP1 LAMB1 MEGF6 AGRN NOTCH1

1.94e-08123296int:CACNA1A
InteractionJAG1 interactions

JAG2 NOTCH1 NOTCH2 JAG1

3.37e-0741294int:JAG1
InteractionEDN3 interactions

JAG2 CRELD2 AGRN NOTCH1 NOTCH2

4.32e-07108295int:EDN3
InteractionJAG2 interactions

JAG2 OIT3 NOTCH1 NOTCH2 JAG1

4.73e-07110295int:JAG2
InteractionNOTCH3 interactions

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

5.41e-07113295int:NOTCH3
InteractionHOXA1 interactions

JAG2 CRELD2 OIT3 MEGF6 AGRN KRT81 NOTCH1

5.65e-07356297int:HOXA1
InteractionWNT3A interactions

JAG2 LRP1 NOTCH1 NOTCH2

7.00e-0749294int:WNT3A
InteractionCFC1 interactions

CRELD2 LAMB1 AGRN NOTCH1 NOTCH2

9.29e-07126295int:CFC1
InteractionIGSF5 interactions

CRELD2 NOTCH1 NOTCH2

9.65e-0714293int:IGSF5
InteractionGFI1B interactions

JAG2 LAMB1 MEGF6 AGRN NOTCH1

1.36e-06136295int:GFI1B
InteractionMAML2 interactions

NOTCH1 NOTCH2 NOTCH4

1.80e-0617293int:MAML2
InteractionPLAT interactions

LRP1 LAMA3 LRP1B NOTCH2

1.94e-0663294int:PLAT
InteractionCCN6 interactions

CRELD2 NOTCH1 NOTCH2

2.56e-0619293int:CCN6
InteractionMAML3 interactions

NOTCH1 NOTCH2 NOTCH4

3.00e-0620293int:MAML3
InteractionMBD1 interactions

JAG2 MEGF6 TNC NOTCH1

4.35e-0677294int:MBD1
InteractionATN1 interactions

JAG2 LRP2 MEGF6 AGRN MEGF11

6.46e-06187295int:ATN1
InteractionLGALS1 interactions

JAG2 LRP2 LAMB1 NOTCH1 NOTCH2 JAG1

6.59e-06332296int:LGALS1
InteractionMFNG interactions

NOTCH1 NOTCH2 JAG1

7.66e-0627293int:MFNG
InteractionELSPBP1 interactions

CRELD2 AGRN NOTCH1 NOTCH2

8.85e-0692294int:ELSPBP1
InteractionDYRK1A interactions

LRP2 LAMB1 SNED1 ADAM23 LRP1B ATRNL1 NOTCH2

1.03e-05552297int:DYRK1A
InteractionTSHR interactions

JAG2 LAMA3 CRELD2 LAMB1

1.05e-0596294int:TSHR
InteractionST14 interactions

JAG2 LAMA3 CRELD2 LAMB1 NOTCH2

1.06e-05207295int:ST14
InteractionDAB1 interactions

LRP1 LRP2 ITGB7 NOTCH1

1.61e-05107294int:DAB1
InteractionATXN7 interactions

JAG2 LAMB1 MEGF6 AGRN

1.73e-05109294int:ATXN7
InteractionWNT10A interactions

CRELD2 NOTCH1 NOTCH2

2.01e-0537293int:WNT10A
InteractionZDHHC15 interactions

LRP1 LRP2 ATRNL1 CRB1

2.97e-05125294int:ZDHHC15
InteractionDLL4 interactions

NOTCH1 NOTCH4

2.99e-056292int:DLL4
InteractionTAFA2 interactions

LAMA3 CRELD2 ATRNL1

4.16e-0547293int:TAFA2
InteractionPATE1 interactions

JAG2 CRELD2 LRP1B

4.72e-0549293int:PATE1
InteractionDKK2 interactions

LRP2 LRP1B NOTCH1

4.72e-0549293int:DKK2
InteractionFOXD4L6 interactions

LRP1B NOTCH1 NOTCH2

4.72e-0549293int:FOXD4L6
InteractionPRG2 interactions

JAG2 CRELD2 LAMC3 NOTCH1 NOTCH2

4.91e-05285295int:PRG2
InteractionSLURP1 interactions

LAMA3 CRELD2 LAMB1 NOTCH2

5.17e-05144294int:SLURP1
InteractionMFAP5 interactions

JAG2 MEGF6 JAG1

5.65e-0552293int:MFAP5
InteractionSERPINE1 interactions

LRP1 LRP2 LRP1B

6.32e-0554293int:SERPINE1
InteractionSMOC1 interactions

LRP1 TNC NOTCH2

6.32e-0554293int:SMOC1
InteractionSHANK3 interactions

JAG2 MEGF6 MEGF11 MEGF10 NOTCH1 NOTCH2

6.33e-05496296int:SHANK3
InteractionLYPD1 interactions

JAG2 LAMB1 NOTCH2

7.84e-0558293int:LYPD1
InteractionANKRD36B interactions

LRP1 LRP2 LRP1B

8.68e-0560293int:ANKRD36B
InteractionMANEA interactions

LAMB1 AGRN ITGB7

8.68e-0560293int:MANEA
InteractionSDF2L1 interactions

JAG2 CRELD2 LAMB1 LAMC3 AGRN

8.75e-05322295int:SDF2L1
InteractionPTPRK interactions

LAMA3 LAMB1 OIT3 LRP1B

1.15e-04177294int:PTPRK
InteractionMFAP2 interactions

JAG2 JAG1

1.31e-0412292int:MFAP2
InteractionSCGB1A1 interactions

LRP2 AGRN

1.31e-0412292int:SCGB1A1
InteractionCNTN1 interactions

TNC NOTCH1 NOTCH2

1.32e-0469293int:CNTN1
InteractionMAML1 interactions

NOTCH1 NOTCH2 NOTCH4

1.56e-0473293int:MAML1
InteractionAPBB1 interactions

LRP1 LRP2 NOTCH1 JAG1

1.67e-04195294int:APBB1
InteractionRNASE4 interactions

LRP1B NOTCH2

1.80e-0414292int:RNASE4
InteractionLFNG interactions

NOTCH1 NOTCH2

1.80e-0414292int:LFNG
InteractionEGFL7 interactions

NOTCH1 NOTCH2 NOTCH4

1.82e-0477293int:EGFL7
InteractionCRP interactions

LAMB1 LAMC3 AGRN

1.82e-0477293int:CRP
InteractionCUBN interactions

LRP1 LRP2

2.08e-0415292int:CUBN
InteractionSCN3A interactions

LRP1 LRP2

2.37e-0416292int:SCN3A
InteractionLRP1B interactions

LRP1 LRP2 LRP1B

2.44e-0485293int:LRP1B
InteractionLY86 interactions

JAG2 CRELD2 LAMB1 LAMC3

2.51e-04217294int:LY86
InteractionNID2 interactions

LAMB1 TNC AGRN

2.53e-0486293int:NID2
InteractionSIRPD interactions

JAG2 CRELD2 NOTCH1

2.53e-0486293int:SIRPD
InteractionPSEN2 interactions

NOTCH1 NOTCH2 NOTCH4

2.53e-0486293int:PSEN2
InteractionOS9 interactions

LAMA3 LAMB1 LRP1B AGRN

2.60e-04219294int:OS9
InteractionTIMP3 interactions

LRP2 LRP1B NOTCH2

2.89e-0490293int:TIMP3
InteractionMDK interactions

LRP1 LRP2 NOTCH2

2.99e-0491293int:MDK
InteractionOLFM3 interactions

LRP1B AGRN

3.02e-0418292int:OLFM3
InteractionNOTCH2 interactions

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

3.12e-04423295int:NOTCH2
InteractionDEFB125 interactions

LRP2 LAMA3

3.74e-0420292int:DEFB125
InteractionZNF224 interactions

LRP2 LRP1B

3.74e-0420292int:ZNF224
InteractionCLU interactions

LRP1 LRP2 LRP1B TNC

3.99e-04245294int:CLU
InteractionNOTCH4 interactions

NOTCH2 NOTCH4

4.13e-0421292int:NOTCH4
InteractionEGFL6 interactions

LRP2 LRP1B

4.13e-0421292int:EGFL6
InteractionCASR interactions

NOTCH1 NOTCH2

4.54e-0422292int:CASR
InteractionZNF431 interactions

TYRP1 NOTCH2

4.54e-0422292int:ZNF431
InteractionDTX4 interactions

NOTCH1 NOTCH2

4.54e-0422292int:DTX4
InteractionWNT2 interactions

NOTCH1 NOTCH2

4.96e-0423292int:WNT2
InteractionSCARF2 interactions

SCARF1 NOTCH2

5.41e-0424292int:SCARF2
InteractionWNT10B interactions

OIT3 NOTCH2

5.88e-0425292int:WNT10B
InteractionCOL6A1 interactions

LAMB1 OIT3 AGRN

6.24e-04117293int:COL6A1
InteractionSEC61B interactions

JAG2 LRP2 LAMB1 LRP1B NOTCH1 NOTCH2

6.50e-04763296int:SEC61B
InteractionGIPC1 interactions

LRP1 LRP2 TYRP1

6.56e-04119293int:GIPC1
InteractionSULF2 interactions

LRP2 LRP1B NOTCH2

6.56e-04119293int:SULF2
InteractionNTF3 interactions

LRP1 LAMB1

6.86e-0427292int:NTF3
InteractionFEZF1 interactions

LRP2 LRP1B

7.38e-0428292int:FEZF1
InteractionGLI4 interactions

LRP2 LRP1B NOTCH2

7.57e-04125293int:GLI4
InteractionTHBS1 interactions

LRP1 LRP2 JAG1

7.92e-04127293int:THBS1
InteractionZNF517 interactions

LRP2 LRP1B

7.92e-0429292int:ZNF517
InteractionCILP2 interactions

OIT3 NOTCH2

9.06e-0431292int:CILP2
InteractionPLAUR interactions

LRP1 LRP1B NOTCH2

9.46e-04135293int:PLAUR
InteractionTMEM106B interactions

CRELD2 LAMB1 LAMC3 NOTCH2

9.51e-04309294int:TMEM106B
InteractionITGB1BP1 interactions

LRP1 LRP2

1.03e-0333292int:ITGB1BP1
InteractionB3GALT4 interactions

CRELD2 NOTCH1

1.03e-0333292int:B3GALT4
InteractionANKS1B interactions

LRP1 LRP2

1.09e-0334292int:ANKS1B
InteractionZNF74 interactions

JAG2 NOTCH1

1.09e-0334292int:ZNF74
InteractionNXPH4 interactions

LRP1 OIT3

1.09e-0334292int:NXPH4
InteractionDTX1 interactions

NOTCH1 NOTCH2

1.16e-0335292int:DTX1
InteractionLPL interactions

LRP1 LRP2

1.16e-0335292int:LPL
InteractionZNF408 interactions

LRP2 LRP1B NOTCH2

1.16e-03145293int:ZNF408
InteractionCLEC2B interactions

JAG2 NOTCH1 NOTCH2

1.21e-03147293int:CLEC2B
InteractionDLK2 interactions

LRP2 NOTCH1

1.22e-0336292int:DLK2
CytobandEnsembl 112 genes in cytogenetic band chr12q13

LRP1 ITGB7 KRT81

2.38e-03423293chr12q13
CytobandEnsembl 112 genes in cytogenetic band chr1p36

MEGF6 AGRN CELA2A

8.91e-03681293chr1p36
GeneFamilyLaminin subunits

LAMA3 LAMB1 LAMC3

2.53e-0712203626
GeneFamilyLow density lipoprotein receptors

LRP1 LRP2 LRP1B

3.29e-0713203634
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SCARF1 MEGF10

4.01e-04272021253
GeneFamilyAnkyrin repeat domain containing

NOTCH1 NOTCH2 NOTCH4

2.28e-03242203403
GeneFamilyFibronectin type III domain containing

SNED1 TNC

1.33e-02160202555
CoexpressionNABA_MATRISOME

LAMA3 CRELD2 LAMB1 SNED1 LAMC3 OIT3 EGF MEGF6 ADAM23 TNC AGRN MEGF11 MEGF10 CELA2A

6.41e-1310082914MM17056
CoexpressionNABA_MATRISOME

LAMA3 CRELD2 LAMB1 SNED1 LAMC3 OIT3 EGF MEGF6 ADAM23 TNC AGRN MEGF11 MEGF10 CELA2A

8.14e-1310262914M5889
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

4.99e-1216295M2207
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 NOTCH1 NOTCH2 JAG1 NOTCH4

4.99e-1216295MM1296
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA3 CRELD2 LAMB1 SNED1 LAMC3 OIT3 TNC AGRN

2.58e-11191298MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA3 CRELD2 LAMB1 SNED1 LAMC3 OIT3 TNC AGRN

3.18e-11196298M3008
CoexpressionNABA_CORE_MATRISOME

LAMA3 CRELD2 LAMB1 SNED1 LAMC3 OIT3 TNC AGRN

4.07e-10270298MM17057
CoexpressionNABA_CORE_MATRISOME

LAMA3 CRELD2 LAMB1 SNED1 LAMC3 OIT3 TNC AGRN

4.70e-10275298M5884
CoexpressionBRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS

NOTCH1 NOTCH2 JAG1

6.79e-088293M9884
CoexpressionNABA_BASEMENT_MEMBRANES

LAMA3 LAMB1 LAMC3 AGRN

1.07e-0740294M5887
CoexpressionFAN_EMBRYONIC_CTX_BIG_GROUPS_BRAIN_ENDOTHELIAL

SCARF1 LAMB1 LAMC3 AGRN NOTCH1 JAG1 NOTCH4

1.15e-07365297M39018
CoexpressionHALLMARK_WNT_BETA_CATENIN_SIGNALING

JAG2 NOTCH1 JAG1 NOTCH4

1.31e-0742294M5895
CoexpressionDESCARTES_FETAL_KIDNEY_MESANGIAL_CELLS

TYRP1 LAMC3 TNC ATRNL1

4.26e-0756294M40224
CoexpressionLU_TUMOR_ANGIOGENESIS_UP

JAG2 NOTCH1 JAG1

2.76e-0625293M9946
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2A

LRP1 LRP2 TNC NOTCH1 NOTCH2 JAG1 CRB1

3.20e-06600297M39055
CoexpressionHALLMARK_NOTCH_SIGNALING

NOTCH1 NOTCH2 JAG1

5.91e-0632293M5903
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP

JAG2 NOTCH2 JAG1 NOTCH4

3.03e-05163294M12112
CoexpressionDESCARTES_FETAL_PANCREAS_VASCULAR_ENDOTHELIAL_CELLS

JAG2 OIT3 NOTCH4

5.08e-0565293M40266
CoexpressionHU_FETAL_RETINA_FIBROBLAST

LAMB1 SNED1 LAMC3 NOTCH2 JAG1

5.92e-05385295M39264
CoexpressionVERRECCHIA_RESPONSE_TO_TGFB1_C4

LAMB1 TNC

6.46e-0511292M566
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

LRP1 LAMA3 TNC NOTCH2

6.73e-05200294M5930
CoexpressionSASAKI_TARGETS_OF_TP73_AND_TP63

JAG2 JAG1

7.75e-0512292M17374
CoexpressionBUSSLINGER_ESOPHAGEAL_QUIESCENT_BASAL_CELLS

JAG2 MEGF6 TNC

8.43e-0577293M40001
CoexpressionMURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL

LAMB1 LAMC3 TNC NOTCH1 NOTCH2 JAG1

8.58e-05681296M39175
CoexpressionROSS_AML_WITH_PML_RARA_FUSION

MEGF6 AGRN JAG1

9.45e-0580293M15368
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2B

LRP1 LRP2 TNC NOTCH1 NOTCH2

1.10e-04439295M39054
CoexpressionNABA_MATRISOME_ASSOCIATED

EGF MEGF6 ADAM23 MEGF11 MEGF10 CELA2A

1.33e-04738296MM17058
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

LRP2 LAMB1 SNED1 LAMC3 MEGF11 NOTCH1 JAG1

1.34e-041074297M1941
CoexpressionLEE_LIVER_CANCER_HEPATOBLAST

LAMA3 TNC

1.40e-0416292M13123
CoexpressionNABA_MATRISOME_ASSOCIATED

EGF MEGF6 ADAM23 MEGF11 MEGF10 CELA2A

1.47e-04751296M5885
CoexpressionMOREIRA_RESPONSE_TO_TSA_DN

NOTCH1 NOTCH2

1.79e-0418292M3506
CoexpressionBOQUEST_STEM_CELL_UP

LRP1 LRP1B TNC NOTCH2

1.88e-04261294M1834
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HPERIC

LRP1 LAMB1 LAMC3 AGRN NOTCH2 JAG1

2.00e-04795296M39050
CoexpressionWOO_LIVER_CANCER_RECURRENCE_UP

JAG2 NOTCH2 JAG1

2.12e-04105293M12602
CoexpressionMURAKAMI_UV_RESPONSE_24HR

ITGB7 NOTCH4

2.22e-0420292M17175
CoexpressionNABA_MATRISOME_BLEO_FIBROTIC_LUNG

LAMA3 TNC

2.22e-0420292MM17053
CoexpressionMURAKAMI_UV_RESPONSE_6HR_DN

ITGB7 NOTCH4

2.45e-0421292M16756
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL3

LRP1 LRP2 LRP1B NOTCH2 CRB1

3.80e-04574295M39056
CoexpressionDESCARTES_FETAL_ADRENAL_SCHWANN_CELLS

ADAM23 AGRN MEGF10

3.96e-04130293M40147
CoexpressionLAKE_ADULT_KIDNEY_C13_THICK_ASCENDING_LIMB

LAMB1 EGF LRP1B

4.05e-04131293M39232
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2C

LRP1 LRP1B TNC NOTCH1

4.31e-04325294M39053
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN

EGF NOTCH1 NOTCH2

4.43e-04135293M5825
CoexpressionDESCARTES_FETAL_CEREBRUM_VASCULAR_ENDOTHELIAL_CELLS

JAG2 LAMC3 MEGF6 AGRN NOTCH4

4.48e-04595295M40167
CoexpressionPDGF_UP.V1_DN

LRP2 EGF ADAM23

4.52e-04136293M2832
CoexpressionNABA_MATRISOME_HIGHLY_METASTATIC_BREAST_CANCER_TUMOR_CELL_DERIVED

SNED1 AGRN

4.71e-0429292M47987
CoexpressionNABA_MATRISOME_METASTATIC_LUNG_LYMPH_NODE_METASTASIS

TNC AGRN

4.71e-0429292MM17055
CoexpressionNABA_SECRETED_FACTORS

EGF MEGF6 MEGF11 MEGF10

5.00e-04338294MM17064
CoexpressionKRAS.PROSTATE_UP.V1_DN

EGF ADAM23 ITGB7

5.03e-04141293M2901
CoexpressionNABA_SECRETED_FACTORS

EGF MEGF6 MEGF11 MEGF10

5.28e-04343294M5883
CoexpressionTHEODOROU_MAMMARY_TUMORIGENESIS

LAMB1 NOTCH4

5.39e-0431292M1291
CoexpressionDASU_IL6_SIGNALING_SCAR_UP

TNC AGRN

5.39e-0431292M292
CoexpressionMURARO_PANCREAS_ENDOTHELIAL_CELL

LAMB1 NOTCH1 JAG1 NOTCH4

6.47e-04362294M39176
CoexpressionWANG_RESPONSE_TO_BEXAROTENE_UP

LAMB1 EGF

6.49e-0434292M1263
CoexpressionLIU_CDX2_TARGETS_UP

JAG1 NOTCH4

6.88e-0435292M16637
CoexpressionNABA_MATRISOME_PRIMARY_METASTATIC_LUNG_TUMOR

TNC AGRN

6.88e-0435292MM17054
CoexpressionHALLMARK_ANGIOGENESIS

JAG2 JAG1

7.27e-0436292M5944
CoexpressionSNIJDERS_AMPLIFIED_IN_HEAD_AND_NECK_TUMORS

LAMA3 JAG1

7.69e-0437292M12802
CoexpressionVERRECCHIA_DELAYED_RESPONSE_TO_TGFB1

LAMB1 TNC

7.69e-0437292M16643
CoexpressionTHEODOROU_MAMMARY_TUMORIGENESIS

LAMB1 NOTCH4

7.69e-0437292MM1121
CoexpressionHUANG_FOXA2_TARGETS_DN

TNC KRT81

8.11e-0438292M16701
CoexpressionMCBRYAN_PUBERTAL_TGFB1_TARGETS_UP

TNC JAG1 NOTCH4

8.36e-04168293M1124
CoexpressionGSE7768_OVA_WITH_LPS_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN

SCARF1 KREMEN1 NOTCH2

8.65e-04170293M6855
CoexpressionNAKAYA_PBMC_FLUAD_MALE_AGE_14_27YO_1D_POSTBOOST_VS_0D_PREIMM_MF59_ADJUVANTED_1DY_ATIV_UP

SCARF1 KREMEN1

8.98e-0440292M40897
CoexpressionGSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_UP

KREMEN1 NOTCH1 NOTCH2

9.41e-04175293M6723
CoexpressionNABA_MATRISOME_HIGHLY_METASTATIC_BREAST_CANCER

SNED1 AGRN

9.44e-0441292M47988
CoexpressionMOHANKUMAR_HOXA1_TARGETS_DN

TYRP1 LRP1B TNC

9.56e-04176293M9032
CoexpressionULE_SPLICING_VIA_NOVA2

LRP1B AGRN

1.04e-0343292MM666
CoexpressionULE_SPLICING_VIA_NOVA2

LRP1B AGRN

1.04e-0343292M1551
CoexpressionMCBRYAN_PUBERTAL_TGFB1_TARGETS_UP

TNC JAG1 NOTCH4

1.05e-03182293MM993
CoexpressionMENON_FETAL_KIDNEY_2_NEPHRON_PROGENITOR_CELLS

LAMB1 JAG1

1.09e-0344292M39252
CoexpressionFOSTER_TOLERANT_MACROPHAGE_DN

KREMEN1 TNC AGRN NOTCH1

1.10e-03418294M12676
CoexpressionGSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_TREATED_MACROPHAGE_UP

KREMEN1 KRT81 CRB1

1.16e-03188293M7940
CoexpressionBEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN

JAG2 TNC

1.19e-0346292M6679
CoexpressionJIANG_TIP30_TARGETS_UP

LAMB1 JAG1

1.19e-0346292M12641
CoexpressionGSE2706_LPS_VS_R848_AND_LPS_2H_STIM_DC_UP

LAMC3 MEGF10 JAG1

1.21e-03191293M4722
CoexpressionHEVNER_CORTEX_RADIAL_GLIA_PROGENITORS

LRP2 MEGF10 NOTCH1 NOTCH2

1.25e-03432294MM419
CoexpressionJOHNSTONE_PARVB_TARGETS_3_UP

LRP1 AGRN NOTCH2 JAG1

1.26e-03433294M2240
CoexpressionAIZARANI_LIVER_C21_STELLATE_CELLS_1

LRP1 LAMB1 LAMC3

1.27e-03194293M39122
CoexpressionFOSTER_TOLERANT_MACROPHAGE_DN

KREMEN1 TNC AGRN NOTCH1

1.28e-03435294MM1221
CoexpressionLTE2_UP.V1_DN

LAMA3 NOTCH1 JAG1

1.28e-03195293M2721
CoexpressionLI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN

EGF AGRN

1.29e-0348292M1246
CoexpressionWANG_RESPONSE_TO_BEXAROTENE_UP

LAMB1 EGF

1.29e-0348292MM531
CoexpressionPLASARI_TGFB1_TARGETS_10HR_UP

TNC MEGF10 JAG1

1.30e-03196293M2445
CoexpressionPLASARI_TGFB1_TARGETS_10HR_UP

TNC MEGF10 JAG1

1.32e-03197293MM1320
CoexpressionFAN_EMBRYONIC_CTX_BRAIN_ENDOTHELIAL_1

LAMB1 MEGF6 NOTCH1 NOTCH4

1.33e-03440294M39039
CoexpressionGSE44649_WT_VS_MIR155_KO_NAIVE_CD8_TCELL_UP

LRP1 LAMA3 NOTCH1

1.34e-03198293M9778
CoexpressionGSE32986_UNSTIM_VS_GMCSF_STIM_DC_DN

CRELD2 ADAM23 AGRN

1.36e-03199293M8641
CoexpressionGSE3982_EOSINOPHIL_VS_BCELL_UP

NOTCH1 NOTCH2 JAG1

1.36e-03199293M5406
CoexpressionGSE22025_UNTREATED_VS_TGFB1_TREATED_CD4_TCELL_DN

EGF ITGB7 CELA2A

1.36e-03199293M8385
CoexpressionGSE17721_LPS_VS_PAM3CSK4_1H_BMDC_DN

LRP2 TYRP1 CELA2A

1.36e-03199293M3912
CoexpressionGSE33424_CD161_INT_VS_NEG_CD8_TCELL_DN

CRELD2 ITGB7 ATRNL1

1.38e-03200293M8553
CoexpressionGSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_UP

LAMB1 KRT81 NOTCH1

1.38e-03200293M7283
CoexpressionGSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_1H_DN

LRP2 EGF AGRN

1.38e-03200293M9935
CoexpressionGSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP

ADAM23 KRT81 CRB1

1.38e-03200293M7758
CoexpressionGSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN

LRP1 OIT3 NOTCH2

1.38e-03200293M8648
CoexpressionGSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_DN

MEGF6 AGRN ATRNL1

1.38e-03200293M9370
CoexpressionGSE8835_HEALTHY_VS_CLL_CD8_TCELL_DN

SCARF1 ATRNL1 CELA2A

1.38e-03200293M6263
CoexpressionGSE3203_INFLUENZA_INF_VS_IFNB_TREATED_LN_BCELL_UP

CRELD2 OIT3 ADAM23

1.38e-03200293M6790
CoexpressionGSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_UP

AGRN ITGB7 NOTCH1

1.38e-03200293M8517
CoexpressionGSE23568_CTRL_TRANSDUCED_VS_WT_CD8_TCELL_DN

AGRN ITGB7 NOTCH1

1.38e-03200293M8521
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_500

LAMB1 ADAM23 TNC NOTCH1 NOTCH2 JAG1

9.10e-06370296gudmap_kidney_P3_CapMes_Crym_500
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500

LRP2 LAMB1 AGRN NOTCH1 NOTCH2 JAG1

1.38e-05398296gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

LRP1 LAMB1 ADAM23 TNC ATRNL1 NOTCH2 JAG1

6.59e-05777297gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000

LRP2 LAMB1 TNC AGRN NOTCH1 NOTCH2 JAG1

6.92e-05783297gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_500

LAMB1 AGRN NOTCH1 JAG1

7.17e-05165294gudmap_kidney_P4_CapMesRenVes_Crym_k3_500
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_200

ADAM23 TNC NOTCH2 JAG1

7.35e-05166294gudmap_kidney_P3_CapMes_Crym_200
CoexpressionAtlasJC_hmvEC_top-relative-expression-ranked_2500_k-means-cluster#3

JAG2 LAMA3 AGRN KRT81 JAG1

1.19e-04362295JC_hmvEC_2500_K3
CoexpressionAtlasAravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000

LRP2 TYRP1 TNC KRT81 ATRNL1 MEGF10 CRB1

2.81e-04981297Arv_EB-LF_1000
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

LRP1 LAMB1 TNC ATRNL1 JAG1

3.10e-04445295GSM777043_500
CoexpressionAtlasStromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4

SCARF1 LAMB1 TNC AGRN JAG1

3.26e-04450295GSM777063_500
CoexpressionAtlasStromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4

LRP1 LAMB1 SNED1 TNC JAG1

3.43e-04455295GSM777055_500
CoexpressionAtlasStromal Cells, BEC.MLN, gp38- CD31+, Lymph Node, avg-5

SCARF1 LAMA3 LAMB1 JAG1 NOTCH4

3.47e-04456295GSM777032_500
CoexpressionAtlasStromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4

SCARF1 LAMA3 LAMB1 JAG1 NOTCH4

3.57e-04459295GSM777037_500
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_1000

LAMB1 ADAM23 TNC NOTCH1 NOTCH2 JAG1

4.48e-04749296gudmap_kidney_P3_CapMes_Crym_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

LRP1 LAMB1 TNC ATRNL1 NOTCH2 JAG1

5.11e-04768296gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

LRP1 LAMB1 ADAM23 ATRNL1 NOTCH2 JAG1

5.29e-04773296gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TNC AGRN MEGF10 NOTCH1

5.49e-04281294PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

TNC AGRN MEGF10 NOTCH1

5.49e-04281294PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasEctoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05

LRP2 LAMB1 EGF MEGF6 TNC AGRN NOTCH2 JAG1

5.86e-041466298PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K3

OIT3 TNC NOTCH4

5.92e-04121293facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K3
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_500

ADAM23 TNC NOTCH2

6.21e-04123293gudmap_kidney_P3_CapMes_Crym_k3_500
CoexpressionAtlaskidney_P2_CapMes_Crym_top-relative-expression-ranked_500

ADAM23 TNC NOTCH2 JAG1

6.26e-04291294gudmap_kidney_P2_CapMes_Crym_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000

LAMA3 ADAM23 TNC AGRN MEGF11 MEGF10

6.60e-04806296gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAG2 LAMA3 LAMC3 MEGF6 JAG1 NOTCH4

2.37e-09191296b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCellBasal|World / shred by cell class for mouse tongue

JAG2 LAMA3 LAMB1 MEGF6 AGRN

1.16e-07183295c6729a207526ff4aa48176207b9353176f631fea
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SNED1 MEGF6 TNC ATRNL1

1.16e-071832957eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAG2 LAMC3 MEGF6 JAG1 NOTCH4

1.22e-07185295f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

SCARF1 LRP2 MEGF6 TNC AGRN

1.36e-071892952d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 LAMA3 NOTCH1 NOTCH4

1.39e-07190295632d5dc11765053366d61f0a0c7916111cea4f50
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 MEGF11 NOTCH1 NOTCH4

1.39e-0719029538a815abf0ac5cac6071737cadc54a514f62d37d
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 MEGF11 NOTCH1 NOTCH4

1.39e-07190295bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 MEGF11 NOTCH1 NOTCH4

1.39e-07190295d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCell10x5'v1-week_12-13-Endothelial-stroma-tip_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

JAG2 LAMB1 OIT3 AGRN NOTCH4

1.43e-07191295cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 LAMA3 NOTCH1 NOTCH4

1.47e-071922955012cc3ec0766f06af447463413422b484446c43
ToppCellfacs-MAT-Fat-24m-Endothelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1 JAG1 NOTCH4

1.51e-07193295ba9a47e2dc01efa6d2a99b1631d4951fac2648d4
ToppCellfacs-MAT-Fat-24m-Endothelial-endothelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1 JAG1 NOTCH4

1.51e-07193295724bb613fa434add5b1c5586b629328f819fbdfe
ToppCellfacs-MAT-Fat-24m-Endothelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1 JAG1 NOTCH4

1.51e-07193295737e540c72a3cfe8dbd4c0f139f7d729a166793a
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

LRP1 LAMB1 SNED1 TNC NOTCH2

1.55e-07194295d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 SNED1 LAMC3 TNC ATRNL1

1.59e-07195295d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 AGRN JAG1 NOTCH4

1.59e-07195295a432d69b0172211ee4d53675936a1dc9ce1ae1f0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 SNED1 LAMC3 TNC ATRNL1

1.63e-07196295a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 SNED1 LAMC3 TNC ATRNL1

1.63e-071962953e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 SNED1 LAMC3 TNC ATRNL1

1.67e-071972956d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 SNED1 LAMC3 TNC ATRNL1

1.67e-07197295b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 SNED1 LAMC3 TNC ATRNL1

1.67e-07197295c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 LAMC3 TNC ATRNL1 NOTCH2

1.71e-07198295a860246bcea847249a78fd2e86ed8e04371060db
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-tip_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

JAG2 LAMB1 OIT3 AGRN NOTCH4

1.75e-071992951c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-3|TCGA-Adrenal / Sample_Type by Project: Shred V9

SCARF1 JAG2 NOTCH1 NOTCH4

3.50e-0616129452239a887799362256ecd7e740b716b88ed59a62
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

LAMA3 TNC JAG1 CELA2A

3.86e-06165294f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 LAMC3 TNC ATRNL1

4.44e-06171294972fab891135bd755d5526cbc5a963200067b0a6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 LAMC3 TNC ATRNL1

4.44e-061712942a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

LAMA3 TNC JAG1 CELA2A

4.44e-06171294e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

JAG2 NOTCH1 NOTCH4 CRB1

4.55e-06172294c84cab89c97d647b8a256fd08e33d9102810febd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMC3 TNC ATRNL1 NOTCH2

4.87e-06175294910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMC3 TNC ATRNL1 NOTCH2

4.87e-06175294f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

LRP2 LAMB1 LRP1B MEGF11

4.98e-0617629436f77d878a53b30465b0dea8333a3865dba75613
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

5.56e-061812946d1f1ad35778a2a227f966f11f6edd8e89452576
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 LAMA3 JAG1 NOTCH4

5.94e-06184294087666ba949b129c53d7ace40f9e543e3875a7de
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

ADAM23 ATRNL1 MEGF10 JAG1

5.94e-06184294ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellfacs-Trachea-nan-24m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1 NOTCH4

6.06e-06185294dec60254204014083ff3b4aec0cc75410950a486
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP1 LAMB1 SNED1 TNC

6.06e-061852948f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellfacs-Trachea-nan-24m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1 NOTCH4

6.06e-06185294201465dc0d7aa0336a36d37805cae1155a5adfe1
ToppCellfacs-Trachea-nan-24m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1 NOTCH4

6.06e-06185294334f006c3ef33338ff8d649309d3f448733a3a99
ToppCelldroplet-Heart-nan-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 MEGF6 NOTCH1 NOTCH4

6.06e-06185294a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCelldroplet-Bladder-Unstain-18m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 LAMB1 LAMC3 NOTCH4

6.20e-06186294e3a14f3ccadbf3211822c67b8956ee01f563307a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TNC MEGF10 NOTCH1 NOTCH2

6.33e-06187294dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TNC MEGF10 NOTCH1 NOTCH2

6.33e-06187294ae90c263f80c36a410150d499e268d198944a3d9
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JAG2 OIT3 NOTCH1 NOTCH4

6.33e-0618729425efb82afe863a853ecdd781ad89026c993aaa67
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAG2 MEGF6 JAG1 NOTCH4

6.33e-06187294e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

JAG2 NOTCH1 JAG1 NOTCH4

6.46e-06188294366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SCARF1 AGRN NOTCH1 JAG1

6.46e-0618829459f276e23c8380bae57d7ecca3a8b83df4bc150b
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 OIT3 NOTCH4

6.46e-06188294b294d6658e79328bd6fa33223e8c70117ba9789b
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 LAMC3 KREMEN1 TNC

6.46e-06188294997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNED1 LAMC3 TNC MEGF10

6.60e-06189294a5306561026e4dfcc39beeb785e5108ac595d136
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LAMB1 SNED1 TNC

6.60e-06189294a153b83314cf52808f685296cff8c95af3f4983d
ToppCellfacs-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNED1 LAMC3 TNC MEGF10

6.60e-06189294381058f55908f84375b54601d617389ef43ab855
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AGRN NOTCH1 JAG1 NOTCH4

6.60e-061892949da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNED1 LAMC3 TNC MEGF10

6.60e-06189294302b950a6ad578f8aeff7ea6fd15fe631225287d
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LAMB1 SNED1 TNC

6.60e-061892942a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

6.60e-06189294c734e5693808a0333139e87bd5be2597a9252afe
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEGF6 NOTCH1 JAG1 NOTCH4

6.60e-061892941e1afa66b32ae752c0a42b02b80f10205464569c
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 TNC ATRNL1 NOTCH2

6.60e-0618929445e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMC3 TNC ATRNL1 NOTCH2

6.74e-061902941121eb607a984c59fbffe7220837fc178745aa55
ToppCellIPF-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

LAMA3 TNC NOTCH1 NOTCH4

6.74e-061902944f15842b424eefadbfe451875e517cf70e29607f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

6.74e-061902942306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMC3 TNC ATRNL1 NOTCH2

6.74e-06190294048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

6.74e-061902942e592323085ba9c019d678ac2a784462ab470ed9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

6.74e-061902941f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEGF6 NOTCH1 JAG1 NOTCH4

6.74e-06190294d87b9e9ca863270a9c7f61674271a6440c97d1f4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

6.74e-06190294445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LAMB1 SNED1 TNC

6.74e-06190294d60395739458d7f47a3350ade751fe3819500320
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

6.88e-06191294a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LAMB1 SNED1 TNC

6.88e-06191294b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 NOTCH1 NOTCH4

6.88e-0619129479b399496bd7322a1d53c43378f48695fd09a5d9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

6.88e-06191294c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellfacs-Trachea-24m-Endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 NOTCH1 NOTCH4

6.88e-061912949c6d5d045781c6506ae80e318427ef1e0d87f45c
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SNED1 TNC NOTCH2

6.88e-0619129414057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AGRN NOTCH1 JAG1 NOTCH4

6.88e-061912943307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 NOTCH1 NOTCH4

6.88e-061912941b1e943709d0c3283a980c7c965ef1f110506a29
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

6.88e-06191294806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

6.88e-06191294cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

6.88e-06191294107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCell10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

JAG2 LAMB1 SNED1 AGRN

6.88e-06191294dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

6.88e-06191294bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

7.02e-061922949093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature2_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 OIT3 NOTCH4

7.02e-06192294f68e6cbde87678122da1b5c0061904cfb7d04bf5
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEGF6 NOTCH1 JAG1 NOTCH4

7.02e-06192294285a9d332a1e07b94f222d4b518dd56928b9e075
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1 NOTCH4

7.02e-061922948f20d3511dcb44445592b17d005a53da0052ae56
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

7.02e-061922949ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 OIT3 ADAM23 NOTCH1

7.02e-061922942bfac6b3956265205ca47d06888851ed68b65999
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LAMB1 SNED1 TNC

7.02e-06192294dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LAMB1 SNED1 TNC

7.02e-06192294162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial-endothelial_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1 NOTCH4

7.02e-061922940986b7900021efe2a4df84a935e7c9a0af1b0e57
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SNED1 MEGF6 ATRNL1 JAG1

7.02e-06192294c4efc170852abbcf0c53c2b0f8a0cc9fe7f116c8
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

LRP1 LAMB1 SNED1 TNC

7.02e-0619229460b1312e84f6d6448365a952469c506c00b5fe93
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 NOTCH1 NOTCH4

7.02e-06192294b28d294e42b303d1db6060231d84d7b9e4d9fccf
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 OIT3 ADAM23 NOTCH1

7.02e-06192294d525f7f088a53110912600a7c9f6d33b9270d534
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 OIT3 NOTCH4

7.17e-061932942661ad9107ed9231e4afea4442a79051139a31df
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 OIT3 NOTCH4

7.17e-06193294d338a7c0585b69947c37f44aa0381619493e31ea
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMC3 TNC ATRNL1

7.17e-06193294f1199518c3626fd29bfce65070dd21a660671213
ToppCelldroplet-Heart-HEART-1m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEGF6 AGRN MEGF11 NOTCH1

7.17e-06193294d0a5f212f8e8a13dbbe3e41df92548ef82eef70b
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TYRP1 LAMC3 ATRNL1 JAG1

7.17e-06193294000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

JAG2 SNED1 JAG1 NOTCH4

7.17e-061932942e72309607902dabe3218888b22a77fe941f3570
ComputationalAdhesion molecules.

LAMA3 LAMB1 TNC ITGB7

1.73e-04141224MODULE_122
ComputationalIntermediate filaments and MT.

LAMA3 LAMB1 TNC

3.42e-0468223MODULE_438
ComputationalGenes in the cancer module 275.

TNC ITGB7

4.72e-0416222MODULE_275
ComputationalDevelopmental processes.

LAMA3 EGF ADAM23 ITGB7 JAG1

4.72e-04333225MODULE_220
Druglead stearate

JAG2 EGF NOTCH2 JAG1 NOTCH4

6.71e-0884295CID000061258
DrugLMWH

SCARF1 LRP1 LRP2 LAMA3 LAMB1 LAMC3 EGF TNC AGRN

8.48e-08663299CID000000772
DrugAC1L1G72

LAMA3 LAMB1 LAMC3

3.04e-0711293CID000003553
DrugRgd Peptide

LAMA3 LAMB1 LAMC3 EGF TNC ITGB7

4.88e-07239296CID000104802
Drugkalinin

LAMA3 LAMB1 LAMC3 TNC

6.92e-0755294CID000032518
Druganad

EGF NOTCH2 JAG1

8.37e-0715293CID005287574
DrugLG 5

LAMA3 LAMB1 LAMC3 AGRN

9.85e-0760294CID011840957
Drugnapabucasin

EGF NOTCH1 NOTCH2 JAG1

1.28e-0664294ctd:C000621033
Drugdysprosium

LAMA3 LAMB1 LAMC3 AGRN

2.30e-0674294CID000023912
Drug2-amino-5-methylpyridine

LAMA3 LAMB1 LAMC3 AGRN

2.69e-0677294CID000015348
DrugSikvav

LAMA3 LAMB1 TNC

3.69e-0624293CID005487517
DrugAmikacin hydrate [37517-28-5]; Up 200; 6.6uM; PC3; HT_HG-U133A

LRP2 SNED1 ITGB7 ATRNL1 NOTCH2

4.51e-061962956715_UP
Drugmonatepil

LRP1 LRP2 LRP1B

6.64e-0629293CID000060810
DrugAC1L1B58

LAMA3 LAMB1 LAMC3

6.64e-0629293CID000001288
Drugcolchine

LRP2 LAMA3 LAMB1 LAMC3 EGF TNC

7.46e-06383296CID000002833
Drugchondroitin sulfate

LAMA3 LAMB1 EGF TNC AGRN KRT81

1.15e-05413296CID000024766
DrugB-Ms

LAMA3 LAMB1 TNC NOTCH2

1.29e-05114294CID000445091
DrugCalcort

LAMA3 LAMB1 LAMC3

1.52e-0538293CID000026709
DrugAC1L1B6T

TYRP1 AGRN JAG1

1.52e-0538293CID000001308
DrugD 247

EGF TNC

1.56e-055292CID003048156
DrugAC1O0B8G

JAG2 LAMA3 LAMB1 LAMC3 AGRN

1.84e-05262295CID000091605
Drugenzacamene

EGF NOTCH2 JAG1 NOTCH4

2.09e-05129294ctd:C038939
DrugN-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester

NOTCH1 NOTCH2 JAG1

2.38e-0544293ctd:C419410
DrugReidispongiolide C

LRP1 LAMA3 LAMB1 EGF TNC

2.49e-05279295CID005289285
Drugoctylmethoxycinnamate

EGF NOTCH2 JAG1 NOTCH4

2.81e-05139294ctd:C118580
DrugAC1L1JJ0

EGF JAG1

3.28e-057292CID000005061
DrugJmv 320

EGF JAG1

3.28e-057292CID003081775
DrugAC1L1GUQ

JAG2 NOTCH2 JAG1

3.50e-0550293CID000003849
DrugVerteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A

LAMA3 LAMB1 AGRN NOTCH2

4.30e-051552946817_DN
DrugAC1L1KKK

EGF TNC

4.37e-058292CID000005539
DrugI-Q-S

LAMA3 LAMB1 LAMC3 KREMEN1

4.41e-05156294CID000003540
Drug2,4-diaminopyrimidine

LAMA3 LAMB1 AGRN

4.41e-0554293CID000067431
Drugbutylparaben

EGF NOTCH2 JAG1 NOTCH4

4.52e-05157294ctd:C038091
Drug25-hydroxycholesterol

LRP1 LRP2 LRP1B NOTCH2

4.86e-05160294CID000065094
Drugprobucol

SCARF1 LRP1 LRP2 LRP1B

5.11e-05162294CID000004912
Drugcoprogen

LRP1 LRP2

5.61e-059292CID006323272
DrugA-state

EGF TNC

5.61e-059292CID005460479
DrugCC270

LAMA3 LAMB1 LAMC3

5.76e-0559293CID006918852
DrugAC1L9INI

LAMA3 LAMB1 TNC

5.76e-0559293CID000445839
DrugEpi Lovastatin

SCARF1 LRP1 LRP2 EGF LRP1B

6.47e-05341295CID000003962
DrugA25152

JAG2 NOTCH2 JAG1

6.68e-0562293CID000002956
Drug25-azacoprostane

LRP1 LRP2

7.00e-0510292CID000162243
Drug2'-deoxythymidylyl-(3'-5')-2'-deoxyadenosine

NOTCH1 JAG1

7.00e-0510292ctd:C028145
Drugsagamicin

TNC JAG1

7.00e-0510292CID000107677
DrugBM165

LAMA3 LAMB1

8.55e-0511292CID003352881
DrugCloperastine hydrochloride [14984-68-0]; Up 200; 11uM; PC3; HT_HG-U133A

LRP1 CRELD2 MEGF6 AGRN

8.73e-051862944271_UP
DrugMiconazole [22916-47-8]; Up 200; 9.6uM; PC3; HG-U133A

LRP1 CRELD2 NOTCH1 JAG1

1.01e-041932941896_UP
DrugHemicholinium bromide [312-45-8]; Down 200; 7uM; PC3; HT_HG-U133A

LRP1 ADAM23 ITGB7 JAG1

1.05e-041952946739_DN
DrugFluorometholone [426-13-1]; Up 200; 10.6uM; PC3; HT_HG-U133A

LRP1 ADAM23 ITGB7 CRB1

1.07e-041962945771_UP
DrugSTOCK1N-35215; Up 200; 10uM; PC3; HT_HG-U133A

LAMC3 EGF ADAM23 ITGB7

1.07e-041962946380_UP
DrugDroperidol [548-73-2]; Down 200; 10.6uM; PC3; HT_HG-U133A

SNED1 EGF ITGB7 NOTCH2

1.07e-041962944629_DN
DrugBetamethasone [378-44-9]; Down 200; 10.2uM; PC3; HT_HG-U133A

ADAM23 TNC ITGB7 JAG1

1.07e-041962946728_DN
DrugGemfibrozil [25812-30-0]; Up 200; 16uM; PC3; HT_HG-U133A

LRP1 SNED1 ITGB7 JAG1

1.09e-041972945069_UP
Drugisocycloheximide

LRP1 LRP2 LAMA3 LAMB1 LAMC3 EGF LRP1B

1.11e-04905297CID000002900
DrugIsoflupredone acetate [338-98-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A

LRP2 LAMB1 ADAM23 NOTCH2

1.11e-041982945545_DN
Drug0225151-0000 [351320-15-5]; Up 200; 10uM; MCF7; HT_HG-U133A

SCARF1 EGF MEGF6 JAG1

1.11e-041982946384_UP
DrugTranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; MCF7; HT_HG-U133A

SNED1 EGF MEGF6 JAG1

1.11e-041982945996_UP
DrugRanitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A

LRP2 LAMA3 MEGF6 JAG1

1.11e-041982945425_UP
DrugTerbutaline hemisulfate [23031-32-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A

MEGF6 ADAM23 ATRNL1 JAG1

1.13e-041992943202_UP
DrugDiperodon hydrochloride [537-12-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A

SNED1 TYRP1 ITGB7 ATRNL1

1.16e-042002946836_UP
DrugDelsoline [509-18-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A

LRP2 LAMC3 EGF TNC

1.16e-042002946075_UP
DrugFlucytosine [2022-85-7]; Up 200; 31uM; MCF7; HT_HG-U133A

LRP2 ATRNL1 NOTCH2 JAG1

1.16e-042002946450_UP
DrugAndrogen Antagonists

EGF NOTCH2 NOTCH4

1.18e-0475293ctd:D000726
DrugYIGSR

LAMA3 LAMB1 LAMC3

1.38e-0479293CID000123977
Drug2-[(1R,2R,3S,4R,5R,6S)-2-[(2R,5S)-3-[(3S,4S,5R,6S)-4,5-dihydroxy-3-(methylamino)-6-methylol-tetrahydropyran-2-yl]-4-formyl-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine

LAMA3 LAMB1 LAMC3

1.59e-0483293CID011968896
Drug1-Methyl-3-isobutylxanthine

LAMA3 LAMB1 TYRP1 EGF TNC

1.61e-04414295ctd:D015056
DrugNSC 714187

LAMA3 LAMB1 LAMC3

1.71e-0485293CID005288693
Drug1,2-dimethylhydrazine

LAMA3 LAMB1 LAMC3

1.77e-0486293CID000001322
DrugH-9 dihydrochloride

LAMA3 LAMB1 LAMC3

2.03e-0490293CID000003544
Drugtranylcypromine

LRP1 LAMA3 LAMB1

2.09e-0491293CID000005530
Drugbutylphen

LRP1 TYRP1

2.11e-0417292ctd:C006862
DrugALT-711

LAMA3 LAMB1

3.24e-0421292CID000216304
Drughyaluronan

LAMA3 LAMB1 EGF TNC

3.29e-04263294CID000024759
DrugMRK 003

MEGF11 MEGF10 NOTCH1 NOTCH2 NOTCH4 CRB1

3.34e-04760296ctd:C523799
Drugsterol

SCARF1 LRP1 LRP2 ITGB7

3.39e-04265294CID000001107
Drugbutyrate

LAMA3 LAMB1 LAMC3 EGF ITGB7 KRT81

3.51e-04767296CID000000264
Drugprochloraz

LAMB1 EGF NOTCH2 NOTCH4

3.54e-04268294ctd:C045362
DrugGdrgdsp

LAMA3 LAMB1 TNC

3.56e-04109293CID000115346
DrugAC1L1C2F

LAMA3 LAMB1 NOTCH2

3.66e-04110293CID000001711
Drugpitavastatin

LRP1 LRP2 LRP1B

4.06e-04114293CID005282451
Drugtyrphostin RG13022

EGF JAG1

4.61e-0425292CID000005060
Drugtyrphostin AG 1478

EGF NOTCH1 JAG1

4.95e-04122293ctd:C101044
Drugiodide

SCARF1 LRP1 LRP2 SNED1 EGF

5.19e-04534295CID000024841
DrugLinuron

EGF NOTCH2 NOTCH4

5.70e-04128293ctd:D008044
DiseaseCarcinoma, Pancreatic Ductal

JAG2 NOTCH1 JAG1 NOTCH4

7.88e-0924294C0887833
DiseaseGlioblastoma

JAG2 EGF NOTCH1 NOTCH2 JAG1

1.37e-0879295C0017636
DiseaseGiant Cell Glioblastoma

JAG2 EGF NOTCH1 NOTCH2 JAG1

1.86e-0884295C0334588
DiseaseGlioblastoma Multiforme

JAG2 EGF NOTCH1 NOTCH2 JAG1

7.60e-08111295C1621958
DiseaseHepatic ductular hypoplasia

NOTCH2 JAG1

9.33e-072292C2930797
DiseaseAlagille syndrome (is_implicated_in)

NOTCH2 JAG1

9.33e-072292DOID:9245 (is_implicated_in)
DiseaseAlagille Syndrome 2

NOTCH2 JAG1

9.33e-072292C1857761
DiseaseAlagille Syndrome

NOTCH2 JAG1

9.33e-072292C0085280
DiseaseArteriohepatic dysplasia

NOTCH2 JAG1

9.33e-072292cv:C0085280
DiseaseAlagille Syndrome 1

NOTCH2 JAG1

9.33e-072292C1956125
DiseaseMammary Carcinoma, Human

JAG2 EGF NOTCH1 NOTCH2 JAG1 NOTCH4

1.03e-05525296C4704874
DiseaseMammary Neoplasms, Human

JAG2 EGF NOTCH1 NOTCH2 JAG1 NOTCH4

1.03e-05525296C1257931
DiseaseMammary Neoplasms

JAG2 EGF NOTCH1 NOTCH2 JAG1 NOTCH4

1.06e-05527296C1458155
DiseaseBreast Carcinoma

JAG2 EGF NOTCH1 NOTCH2 JAG1 NOTCH4

1.19e-05538296C0678222
DiseaseSchizophrenia

JAG2 LRP1 LRP2 KREMEN1 MEGF10 JAG1 NOTCH4

1.84e-05883297C0036341
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH1 NOTCH2

1.95e-057292DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH1 NOTCH2

1.95e-057292DOID:3620 (implicated_via_orthology)
DiseaseMalignant neoplasm of skin

NOTCH1 NOTCH2 NOTCH4

2.67e-0559293C0007114
DiseaseSkin Neoplasms

NOTCH1 NOTCH2 NOTCH4

2.67e-0559293C0037286
Diseasehemangiopericytoma (is_marker_for)

NOTCH1 NOTCH4

3.34e-059292DOID:264 (is_marker_for)
Diseasegallbladder cancer (is_implicated_in)

EGF LRP1B

7.23e-0513292DOID:3121 (is_implicated_in)
DiseaseNeoplasm of uncertain or unknown behavior of bladder

NOTCH1 NOTCH2

9.72e-0515292C0496930
DiseaseBenign neoplasm of bladder

NOTCH1 NOTCH2

9.72e-0515292C0154017
DiseaseCarcinoma in situ of bladder

NOTCH1 NOTCH2

9.72e-0515292C0154091
Diseasecancer (implicated_via_orthology)

ITGB7 NOTCH1 NOTCH2 NOTCH4

1.32e-04268294DOID:162 (implicated_via_orthology)
DiseaseCarcinoma of bladder

NOTCH1 NOTCH2

1.41e-0418292C0699885
DiseaseSquamous cell carcinoma

NOTCH1 NOTCH2 NOTCH4

2.44e-04124293C0007137
Diseasecongenital heart disease (is_implicated_in)

NOTCH1 JAG1

2.54e-0424292DOID:1682 (is_implicated_in)
DiseaseCerebral Astrocytoma

NOTCH1 NOTCH2

2.76e-0425292C0750935
DiseaseIntracranial Astrocytoma

NOTCH1 NOTCH2

2.76e-0425292C0750936
DiseasePilocytic Astrocytoma

NOTCH1 NOTCH2

2.76e-0425292C0334583
DiseaseAstrocytoma

NOTCH1 NOTCH2

2.76e-0425292C0004114
DiseaseJuvenile Pilocytic Astrocytoma

NOTCH1 NOTCH2

2.76e-0425292C0280783
DiseaseDiffuse Astrocytoma

NOTCH1 NOTCH2

2.76e-0425292C0280785
DiseaseGrade I Astrocytoma

NOTCH1 NOTCH2

2.76e-0425292C1704230
DiseaseSubependymal Giant Cell Astrocytoma

NOTCH1 NOTCH2

2.76e-0425292C0205768
DiseaseMixed oligoastrocytoma

NOTCH1 NOTCH2

2.76e-0425292C0547065
DiseaseChildhood Cerebral Astrocytoma

NOTCH1 NOTCH2

2.76e-0425292C0338070
Diseasebrain cancer (implicated_via_orthology)

NOTCH1 NOTCH2

2.99e-0426292DOID:1319 (implicated_via_orthology)
DiseaseGemistocytic astrocytoma

NOTCH1 NOTCH2

2.99e-0426292C0334581
DiseaseProtoplasmic astrocytoma

NOTCH1 NOTCH2

2.99e-0426292C0334580
DiseaseFibrillary Astrocytoma

NOTCH1 NOTCH2

2.99e-0426292C0334582
DiseaseAnaplastic astrocytoma

NOTCH1 NOTCH2

3.22e-0427292C0334579
Diseasecolorectal cancer (implicated_via_orthology)

NOTCH1 NOTCH2

3.99e-0430292DOID:9256 (implicated_via_orthology)
Diseaseintestinal cancer (implicated_via_orthology)

NOTCH1 NOTCH2

4.54e-0432292DOID:10155 (implicated_via_orthology)
DiseaseCraniofacial Abnormalities

JAG2 LRP2 NOTCH1

4.79e-04156293C0376634
Diseaselupus nephritis

NOTCH4 CRB1

4.83e-0433292EFO_0005761
Diseasepack-years measurement, systolic blood pressure

LRP2 LRP1B

5.13e-0434292EFO_0006335, EFO_0006526
Diseasecervical cancer

NOTCH1 NOTCH2

5.13e-0434292C4048328
DiseaseMalignant neoplasm of breast

JAG2 EGF NOTCH1 NOTCH2 JAG1 NOTCH4

5.31e-041074296C0006142
Diseaseendometrial cancer (is_marker_for)

NOTCH1 NOTCH4

5.44e-0435292DOID:1380 (is_marker_for)
DiseaseUterine Cervical Neoplasm

NOTCH1 NOTCH2

5.44e-0435292C0007873
Diseaseresponse to radiation, prostate carcinoma, erectile dysfunction

LRP1B CELA2A

6.08e-0437292EFO_0001663, EFO_0004234, GO_0009314
DiseaseLymphoma

NOTCH1 NOTCH2

7.11e-0440292C0024299
DiseaseNeoplasm of uncertain or unknown behavior of breast

NOTCH1 NOTCH2

7.47e-0441292C0496956
DiseaseBreast adenocarcinoma

NOTCH1 NOTCH2

7.47e-0441292C0858252
Diseaserectum cancer

LRP1B MEGF10

7.84e-0442292EFO_1000657
Diseasesevere acute respiratory syndrome, COVID-19

MEGF6 ADAM23 LRP1B MEGF11

9.14e-04447294EFO_0000694, MONDO_0100096

Protein segments in the cluster

PeptideGeneStartEntry
NGAHCSDGPCCNNTS

ADAM23

536

O75077
SACQCNPHGSYGGTC

AGRN

791

O00468
SCNGDSGGPLNCQAS

CELA2A

211

P08217
CQCHNGGTCDAATGQ

MEGF10

281

Q96KG7
GGTCDAATGQCHCSP

MEGF10

286

Q96KG7
SGCASSPCQHGGSCH

NOTCH2

1376

Q04721
HNGGQCSPTTGACEC

MEGF11

321

A6BM72
DSQPCLHGGTCQDGC

NOTCH1

1026

P46531
NHCSNYCQNGGTCVP

LRP1B

4251

Q9NZR2
TGRCVPCNCNGHSNQ

LAMA3

1681

Q16787
PCNCNGHSNQCQDGS

LAMA3

1686

Q16787
GGSCQPCSCNSNGQL

LAMA3

1781

Q16787
PCSCNSNGQLGSCHP

LAMA3

1786

Q16787
CTSNPCANGGSCHEV

JAG2

351

Q9Y219
LCDQCSLNNGGCSHN

LRP1

1181

Q07954
APSCLTCVGHCSNGG

LRP1

4371

Q07954
GCHNNNGGCSHSCLG

OIT3

226

Q8WWZ8
ASGTGCDPCNCNAAH

LAMB1

1076

P07942
CNSVCFGDHTQPCGG

KREMEN1

186

Q96MU8
PLCNGNSCSDFNGGC

LRP2

1346

P98164
SNPCGTNNGGCSHLC

LRP2

3466

P98164
NGTGPLCSGKGHCQC

ITGB7

531

P26010
GHCQCGRCSCSGQSS

ITGB7

541

P26010
CSGCSSPDNGGCSQL

EGF

436

P01133
PTNGGQCTACTCSGH

ATRNL1

1051

Q5VV63
AGDNSCKSNPCHNGG

CRB1

886

P82279
NVCNSNPCLHGGNCE

CRB1

1141

P82279
QGGSQRPCSGNGHCS

CRELD2

141

Q6UXH1
DDCSPNNCSHGGTCQ

JAG1

376

P78504
CASNPCLNGGHCQNE

JAG1

491

P78504
CSQNPCHNGGTCRDL

JAG1

671

P78504
CLCQNGGTCDPVSGH

MEGF6

1046

O75095
SCRNGGLCHASNGSC

MEGF6

1306

O75095
GLCHASNGSCSCGLG

MEGF6

1311

O75095
TACHSGPCLNGGSCN

NOTCH4

731

Q99466
CNASCPAGFHGNNCS

SCARF1

381

Q14162
DSCASGPCHNGGTCF

SNED1

621

Q8TER0
CNGNFSGHNCGTCRP

TYRP1

101

P17643
SCPNDCHGQGRCVNG

TNC

531

P24821
GLDCGQHSCPSDCNN

TNC

586

P24821
QNCNTGSSGCCENSG

XP32

191

Q5T750
PCTCNQHGTCDPNTG

LAMC3

706

Q9Y6N6
GLCAPCGQLNTTCGG

KRT81

466

Q14533