Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase binding	RASA1 MYO9B RHOBTB3 TSC2 TAMALIN IQGAP1 BICD1 RIN1 LLGL1 SYTL5 FGD5 VCL	4.69e-05	360	165	12	GO:0051020
GeneOntologyMolecularFunction	glutamine N-acyltransferase activity	GLYATL1 GLYATL1B	6.79e-05	2	165	2	GO:0047946
GeneOntologyMolecularFunction	GPI-anchor transamidase activity	GPAA1 PIGK	6.79e-05	2	165	2	GO:0003923
GeneOntologyMolecularFunction	small GTPase binding	MYO9B RHOBTB3 TSC2 TAMALIN IQGAP1 BICD1 RIN1 LLGL1 SYTL5 FGD5 VCL	7.64e-05	321	165	11	GO:0031267
GeneOntologyMolecularFunction	denatured protein binding	HSPA1A HSPA1B	2.03e-04	3	165	2	GO:0031249
GeneOntologyMolecularFunction	omega peptidase activity	TRHDE GGT7 GGH	2.87e-04	16	165	3	GO:0008242
GeneOntologyBiologicalProcess	learning or memory	GABRB3 CUX2 ABL1 ABL2 ZZEF1 SLC7A11 SHANK3 ITPR3 RIN1 SLC8A2 SCN2A PAX6 NDRG4 HTT	2.06e-06	373	166	14	GO:0007611
GeneOntologyBiologicalProcess	cognition	GABRB3 CUX2 ABL1 ABL2 ZZEF1 SLC7A11 SHANK3 ITPR3 RIN1 SLC8A2 SCN2A PAX6 NDRG4 HTT	8.74e-06	423	166	14	GO:0050890
GeneOntologyBiologicalProcess	learning	GABRB3 ABL1 ABL2 ZZEF1 SLC7A11 SHANK3 RIN1 SLC8A2 NDRG4 HTT	8.78e-06	212	166	10	GO:0007612
GeneOntologyBiologicalProcess	associative learning	ABL1 ABL2 ZZEF1 SLC7A11 SHANK3 RIN1 NDRG4 HTT	1.05e-05	130	166	8	GO:0008306
GeneOntologyBiologicalProcess	establishment of cell polarity	ABL1 ABL2 MYO9B CAMSAP3 TSC2 LLGL2 LLGL1 PAX6 HTT	1.37e-05	177	166	9	GO:0030010
GeneOntologyBiologicalProcess	cerebellum development	GABRB3 CACNA1A ABL1 ABL2 NCOR2 ATIC PAX6 CPLANE1	1.71e-05	139	166	8	GO:0021549
GeneOntologyBiologicalProcess	metencephalon development	GABRB3 CACNA1A ABL1 ABL2 NCOR2 ATIC PAX6 CPLANE1	3.42e-05	153	166	8	GO:0022037
GeneOntologyBiologicalProcess	learned vocalization behavior or vocal learning	SHANK3 PAX6 HTT	8.06e-05	11	166	3	GO:0098598
GeneOntologyBiologicalProcess	regulation of establishment or maintenance of cell polarity	ABL1 ABL2 LLGL2 LLGL1	9.42e-05	30	166	4	GO:0032878
GeneOntologyBiologicalProcess	behavior	GABRB3 CACNA1A CUX2 ABL1 ABL2 TSC2 ZZEF1 SLC7A11 SHANK3 AXIN1 ITPR3 RIN1 SLC8A2 KCNJ10 SCN2A DMRTA1 PAX6 NDRG4 HTT	1.05e-04	891	166	19	GO:0007610
GeneOntologyBiologicalProcess	Bergmann glial cell differentiation	VIM ABL1 ABL2	1.07e-04	12	166	3	GO:0060020
GeneOntologyBiologicalProcess	auditory behavior	ABL2 SHANK3 HTT	1.75e-04	14	166	3	GO:0031223
GeneOntologyCellularComponent	IgM immunoglobulin complex, circulating	IGKV3D-20 IGKV3D-7 IGKV3-20 IGKV3-15	2.68e-07	8	167	4	GO:0071754
GeneOntologyCellularComponent	pentameric IgM immunoglobulin complex	IGKV3D-20 IGKV3D-7 IGKV3-20 IGKV3-15	2.68e-07	8	167	4	GO:0071756
GeneOntologyCellularComponent	monomeric IgA immunoglobulin complex	IGKV3D-20 IGKV3D-7 IGKV3-20 IGKV3-15	4.80e-07	9	167	4	GO:0071748
GeneOntologyCellularComponent	polymeric IgA immunoglobulin complex	IGKV3D-20 IGKV3D-7 IGKV3-20 IGKV3-15	7.95e-07	10	167	4	GO:0071749
GeneOntologyCellularComponent	IgA immunoglobulin complex, circulating	IGKV3D-20 IGKV3D-7 IGKV3-20 IGKV3-15	7.95e-07	10	167	4	GO:0071746
GeneOntologyCellularComponent	secretory IgA immunoglobulin complex	IGKV3D-20 IGKV3D-7 IGKV3-20 IGKV3-15	7.95e-07	10	167	4	GO:0071751
GeneOntologyCellularComponent	IgA immunoglobulin complex	IGKV3D-20 IGKV3D-7 IGKV3-20 IGKV3-15	5.01e-06	15	167	4	GO:0071745
GeneOntologyCellularComponent	IgM immunoglobulin complex	IGKV3D-20 IGKV3D-7 IGKV3-20 IGKV3-15	5.01e-06	15	167	4	GO:0071753
GeneOntologyCellularComponent	immunoglobulin complex, circulating	IGKV3D-20 IGKV3D-7 IGKV3-20 IGKV3-15	8.62e-06	17	167	4	GO:0042571
GeneOntologyCellularComponent	GPI-anchor transamidase complex	GPAA1 PIGK	6.24e-04	5	167	2	GO:0042765
HumanPheno	Atonic seizure	GABRB3 CACNA1A CUX2 GPAA1 POLR1A ADGRV1 DPM1 SCN2A	8.95e-06	94	58	8	HP:0010819
HumanPheno	Atypical absence seizure	GABRB3 CACNA1A CUX2 ADGRV1 MEN1 SCN2A	1.10e-05	46	58	6	HP:0007270
Domain	F_actin_bind	ABL1 ABL2	7.11e-05	2	158	2	PF08919
Domain	F-actin_binding	ABL1 ABL2	7.11e-05	2	158	2	IPR015015
Domain	FABD	ABL1 ABL2	7.11e-05	2	158	2	SM00808
Domain	G2F	HMCN1 NID1	2.12e-04	3	158	2	SM00682
Domain	K_chnl_volt-dep_ELK	KCNH8 KCNH4	2.12e-04	3	158	2	IPR003950
Domain	LLGL	LLGL2 LLGL1	4.22e-04	4	158	2	PF08366
Domain	G2F	HMCN1 NID1	4.22e-04	4	158	2	PF07474
Domain	NIDOGEN_G2	HMCN1 NID1	4.22e-04	4	158	2	PS50993
Domain	GFP	HMCN1 NID1	4.22e-04	4	158	2	IPR009017
Domain	Lethal2_giant	LLGL2 LLGL1	4.22e-04	4	158	2	IPR000664
Domain	G2_nidogen/fibulin_G2F	HMCN1 NID1	4.22e-04	4	158	2	IPR006605
Domain	LLGL2	LLGL2 LLGL1	4.22e-04	4	158	2	IPR013577
Pathway	REACTOME_BUTYROPHILIN_BTN_FAMILY_INTERACTIONS	XDH BTN3A2 BTN3A1 BTN3A3	2.12e-06	12	117	4	M27738
Pathway	WP_RETT_SYNDROME	TRRAP SHANK3 NCOR2 KCNJ10 SCN2A HTT	2.65e-06	48	117	6	M39759
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	LRWD1 ABL1 MAN2A2 MYO9B HECTD4 MED14 TSC2 ZZEF1 TRRAP BTN3A2 ACOX3 GGT7 ITPR3 TINAGL1 NCOR2 EHBP1L1 HEG1 LLGL2 WIZ SND1 PROM2 ZNRF1 ZNF839 DOCK6 HTT	2.23e-10	1105	171	25	35748872
Pubmed	Mouse immunoglobulin chains. Pattern of sequence variation among kappa chains with limited sequence differences.	IGKV3D-20 IGKV3D-7 IGKV3-20 IGKV3-15	8.40e-09	6	171	4	4691517
Pubmed	Primary structures of N-terminal extra peptide segments linked to the variable and constant regions of immunoglobulin light chain precursors: implications on the organization and controlled expression of immunoglobulin genes.	IGKV3D-20 IGKV3D-7 IGKV3-20 IGKV3-15	8.40e-09	6	171	4	98179
Pubmed	Mechanisms of antibody diversity: multiple genes encode structurally related mouse kappa variable regions.	IGKV3D-20 IGKV3D-7 IGKV3-20 IGKV3-15	8.40e-09	6	171	4	99744
Pubmed	The 3' part of the immunoglobulin kappa locus of the mouse.	IGKV3D-20 IGKV3D-7 IGKV3-20 IGKV3-15	1.95e-08	7	171	4	9603450
Pubmed	Chromosomal localization of five murine HSP70 gene family members: Hsp70-1, Hsp70-2, Hsp70-3, Hsc70t, and Grp78.	VIM ABL1 HSPA1A HSPA1B	6.97e-08	9	171	4	8486356
Pubmed	Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset.	BTN3A2 BTN3A1 BTN3A3	1.17e-07	3	171	3	22767497
Pubmed	Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2.	BTN3A2 BTN3A1 BTN3A3	4.65e-07	4	171	3	39142074
Pubmed	RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration.	ABL1 ABL2 RIN1	1.16e-06	5	171	3	15886098
Pubmed	Heteromeric interactions regulate butyrophilin (BTN) and BTN-like molecules governing γδ T cell biology.	BTN3A2 BTN3A1 BTN3A3	1.16e-06	5	171	3	29339503
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	VIM ATXN2L PITRM1 XDH TRRAP IQGAP1 GGH HSPA1A HSPA1B VCL HTT	1.22e-06	344	171	11	30333137
Pubmed	Phosphorylation and binding partner analysis of the TSC1-TSC2 complex.	TSC2 HSPA1A HSPA1B	2.31e-06	6	171	3	15963462
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	SMG1 CABLES2 ABL1 ABL2 POLR1A TRRAP CDCA8 ACOX3 MAP3K4 AXIN1 BLK NCOR2 SND1 ATIC CPLANE1 HSPA1A HSPA1B	2.85e-06	910	171	17	36736316
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	VIM RBM15 LRWD1 POLR1A MYO9B POLD1 EXOSC3 TRRAP DPM1 ERLIN1 IQGAP1 RIN1 NCOR2 SF3B3 LLGL1 ADSS2 SND1 FHOD1 DDX54 ATIC VCL	3.45e-06	1353	171	21	29467282
Pubmed	The cluster of BTN genes in the extended major histocompatibility complex.	BTN3A2 BTN3A1 BTN3A3	4.03e-06	7	171	3	11170752
Pubmed	A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction.	ABL1 ABL2 RASA1	4.03e-06	7	171	3	1383690
Pubmed	Chaperone protein HYPK interacts with the first 17 amino acid region of Huntingtin and modulates mutant HTT-mediated aggregation and cytotoxicity.	HSPA1A HSPA1B HTT	6.42e-06	8	171	3	25446099
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	VIM P4HA2 GPAA1 PITRM1 POLD1 CAMSAP3 TSC2 GIGYF1 XRCC4 SLC7A11 BDH1 PABIR2 ERLIN1 IQGAP1 RIN1 SF3B3 SND1 ZNRF1 FBXO45 VCL	8.63e-06	1321	171	20	27173435
Pubmed	Molecular characterization of ENU mouse mutagenesis and archives.	PTPRT BRCA2 HTT	9.60e-06	9	171	3	16139793
Pubmed	ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling.	ABL1 ABL2 RASA1	9.60e-06	9	171	3	28086240
Pubmed	Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.	ABL1 ABL2 RASA1 BLK	1.05e-05	28	171	4	18067320
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SMG1 ATXN2L POLR1A HECTD4 EXOSC3 MED14 TRRAP MAP3K4 ITPR3 SND1 DDX54	1.26e-05	440	171	11	34244565
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	VIM ATXN2L RBM15 MYO9B POLD1 MED14 DPM1 BDH1 ERLIN1 AXIN1 IQGAP1 ITPR3 NCOR2 SF3B3 ADSS2 DDX54 ATIC HSPA1A VCL	1.35e-05	1247	171	19	27684187
Pubmed	Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.	ABL1 ABL2 RASA1	1.87e-05	11	171	3	20598684
Pubmed	SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria.	VIM HSPA1A HSPA1B	1.87e-05	11	171	3	23885119
Pubmed	Defining the membrane proteome of NK cells.	ATXN2L GPAA1 PIGK MYO9B POLD1 MED14 DPM1 BTN3A2 ACOX3 ITPR3 NCOR2 BTN3A3 EHBP1L1 FHOD1 EIF4EBP3 DDX54 ATIC RPL3L	1.98e-05	1168	171	18	19946888
Pubmed	Exercise induces hepatosplanchnic release of heat shock protein 72 in humans.	HSPA1A HSPA1B	2.40e-05	2	171	2	12411538
Pubmed	Molecular cloning and analysis of DNA complementary to three mouse Mr = 68,000 heat shock protein mRNAs.	HSPA1A HSPA1B	2.40e-05	2	171	2	2868009
Pubmed	Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients.	HSPA1A HSPA1B	2.40e-05	2	171	2	24328534
Pubmed	In vitro transcription of a human hsp 70 heat shock gene by extracts prepared from heat-shocked and non-heat-shocked human cells.	HSPA1A HSPA1B	2.40e-05	2	171	2	3786141
Pubmed	Integrin-mediated dendrite branch maintenance requires Abelson (Abl) family kinases.	ABL1 ABL2	2.40e-05	2	171	2	15987940
Pubmed	Tyrosine phosphorylation of rasGAP and associated proteins in chronic myelogenous leukemia cell lines.	ABL1 RASA1	2.40e-05	2	171	2	1571536
Pubmed	Characterization of the binding between a 70-kDa heat shock protein, HspA1A, and phosphoinositides.	HSPA1A HSPA1B	2.40e-05	2	171	2	26923070
Pubmed	Correlation of genetic polymorphisms with clinical outcomes in pemetrexed-treated advanced lung adenocarcinoma patients.	GGH ATIC	2.40e-05	2	171	2	25823786
Pubmed	Surface expression of HSP72 by LPS-stimulated neutrophils facilitates gammadeltaT cell-mediated killing.	HSPA1A HSPA1B	2.40e-05	2	171	2	16482515
Pubmed	Effect of hyaluronan oligosaccharides on the expression of heat shock protein 72.	HSPA1A HSPA1B	2.40e-05	2	171	2	11864979
Pubmed	The tumor suppressor Lgl1 regulates NMII-A cellular distribution and focal adhesion morphology to optimize cell migration.	LLGL2 LLGL1	2.40e-05	2	171	2	22219375
Pubmed	The Abl and Arg kinases mediate distinct modes of phagocytosis and are required for maximal Leishmania infection.	ABL1 ABL2	2.40e-05	2	171	2	22665498
Pubmed	Hippocampal 72-kDa heat shock protein expression varies according to mice learning performance independently from chronic exposure to stress.	HSPA1A HSPA1B	2.40e-05	2	171	2	15719414
Pubmed	Hsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis without increased bleeding risk.	HSPA1A HSPA1B	2.40e-05	2	171	2	26976620
Pubmed	Hugl1 and Hugl2 in mammary epithelial cells: polarity, proliferation, and differentiation.	LLGL2 LLGL1	2.40e-05	2	171	2	23110097
Pubmed	Alternative splicing and expressivity of the Axin(Fu) allele in mice.	AXIN1 ITPR3	2.40e-05	2	171	2	11703504
Pubmed	Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody.	HSPA1A HSPA1B	2.40e-05	2	171	2	21187371
Pubmed	The expression of the non-receptor tyrosine kinases Arg and c-abl is differently modulated in B lymphoid cells at different stages of differentiation.	ABL1 ABL2	2.40e-05	2	171	2	12220663
Pubmed	Radiation therapy induces circulating serum Hsp72 in patients with prostate cancer.	HSPA1A HSPA1B	2.40e-05	2	171	2	20430459
Pubmed	Intrinsically disordered proteins as molecular shields.	HSPA1A HTT	2.40e-05	2	171	2	21909508
Pubmed	Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia.	HSPA1A HSPA1B	2.40e-05	2	171	2	20235222
Pubmed	Genetic determinants of HSP70 gene expression following heat shock.	HSPA1A HSPA1B	2.40e-05	2	171	2	20876613
Pubmed	The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange.	HSPA1A HSPA1B	2.40e-05	2	171	2	20223214
Pubmed	Women with undiagnosed colorectal adenocarcinomas presenting with ovarian metastases: clinicopathologic features and comparison with women having known colorectal adenocarcinomas and ovarian involvement.	KRT7 MUC16	2.40e-05	2	171	2	18317225
Pubmed	Identification of genes downstream of Pax6 in the mouse lens using cDNA microarrays.	EHBP1L1 PAX6	2.40e-05	2	171	2	11790784
Pubmed	Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells.	HSPA1A HSPA1B	2.40e-05	2	171	2	20093776
Pubmed	Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes.	ABL1 ABL2	2.40e-05	2	171	2	11279004
Pubmed	Bacterial infection elicits heat shock protein 72 release from pleural mesothelial cells.	HSPA1A HSPA1B	2.40e-05	2	171	2	23704948
Pubmed	Structure and expression of the human gene encoding major heat shock protein HSP70.	HSPA1A HSPA1B	2.40e-05	2	171	2	2858050
Pubmed	Nuclear heat shock protein 72 as a negative regulator of oxidative stress (hydrogen peroxide)-induced HMGB1 cytoplasmic translocation and release.	HSPA1A HSPA1B	2.40e-05	2	171	2	17513788
Pubmed	IL-6 activates HSP72 gene expression in human skeletal muscle.	HSPA1A HSPA1B	2.40e-05	2	171	2	12207910
Pubmed	Inducing heat shock protein 70 expression provides a robust antithrombotic effect with minimal bleeding risk.	HSPA1A HSPA1B	2.40e-05	2	171	2	28837204
Pubmed	Concurrent action of purifying selection and gene conversion results in extreme conservation of the major stress-inducible Hsp70 genes in mammals.	HSPA1A HSPA1B	2.40e-05	2	171	2	29572464
Pubmed	Protective effect of heat shock proteins 70.1 and 70.3 on retinal photic injury after systemic hyperthermia.	HSPA1A HSPA1B	2.40e-05	2	171	2	15988927
Pubmed	Abl tyrosine kinase promotes dorsal ruffles but restrains lamellipodia extension during cell spreading on fibronectin.	ABL1 ABL2	2.40e-05	2	171	2	17686996
Pubmed	Huntingtin is associated with cytomatrix proteins at the presynaptic terminal.	BSN HTT	2.40e-05	2	171	2	25461618
Pubmed	Hsp70 (HSPA1) Lysine Methylation Status as a Potential Prognostic Factor in Metastatic High-Grade Serous Carcinoma.	HSPA1A HSPA1B	2.40e-05	2	171	2	26448330
Pubmed	[Effect of Staphylococcal Nuclease and Tudor Domain Containing 1/SLC7A11 on the Occurrence and Development of Osteosarcoma by Inhibiting Ferroptosis].	SLC7A11 SND1	2.40e-05	2	171	2	38433625
Pubmed	HSP70.1 and -70.3 are required for late-phase protection induced by ischemic preconditioning of mouse hearts.	HSPA1A HSPA1B	2.40e-05	2	171	2	12714332
Pubmed	Inflammation-induced, 3'UTR-dependent translational inhibition of Hsp70 mRNA impairs intestinal homeostasis.	HSPA1A HSPA1B	2.40e-05	2	171	2	19299581
Pubmed	Insights into regulation and function of the major stress-induced hsp70 molecular chaperone in vivo: analysis of mice with targeted gene disruption of the hsp70.1 or hsp70.3 gene.	HSPA1A HSPA1B	2.40e-05	2	171	2	11713291
Pubmed	ABL tyrosine kinases: evolution of function, regulation, and specificity.	ABL1 ABL2	2.40e-05	2	171	2	20841568
Pubmed	Heat shock protein 72 (Hsp72) improves long term recovery after focal cerebral ischemia in mice.	HSPA1A HSPA1B	2.40e-05	2	171	2	21108992
Pubmed	Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70).	HSPA1A HSPA1B	2.40e-05	2	171	2	31320473
Pubmed	hsp72, a host determinant of measles virus neurovirulence.	HSPA1A HSPA1B	2.40e-05	2	171	2	16971451
Pubmed	Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane.	ABL2 RASA1	2.40e-05	2	171	2	16971514
Pubmed	Heat shock protein 70 promotes lipogenesis in HepG2 cells.	HSPA1A HSPA1B	2.40e-05	2	171	2	29631603
Pubmed	Coordinated post-transcriptional regulation of Hsp70.3 gene expression by microRNA and alternative polyadenylation.	HSPA1A HSPA1B	2.40e-05	2	171	2	21757701
Pubmed	Role of membrane Hsp70 in radiation sensitivity of tumor cells.	HSPA1A HSPA1B	2.40e-05	2	171	2	26197988
Pubmed	Hsp72 overexpression accelerates the recovery from caerulein-induced pancreatitis.	HSPA1A HSPA1B	2.40e-05	2	171	2	22792201
Pubmed	Abl family tyrosine kinases regulate sialylated ganglioside receptors for polyomavirus.	ABL1 ABL2	2.40e-05	2	171	2	20181697
Pubmed	Heat shock protein 70 alters the endosome-lysosomal localization of huntingtin.	HSPA1B HTT	2.40e-05	2	171	2	17334227
Pubmed	Inhibition of hsp70-1 and hsp70-3 expression disrupts preimplantation embryogenesis and heightens embryo sensitivity to arsenic.	HSPA1A HSPA1B	2.40e-05	2	171	2	9820195
Pubmed	Surface expression of a C-terminal alpha-helix region in heat shock protein 72 on murine LL/2 lung carcinoma can be recognized by innate immune sentinels.	HSPA1A HSPA1B	2.40e-05	2	171	2	19157555
Pubmed	Heat Shock Protein 70 Is Involved in the Efficiency of Preconditioning with Cyclosporine A in Renal Ischemia Reperfusion Injury by Modulating Mitochondrial Functions.	HSPA1A HSPA1B	2.40e-05	2	171	2	37298493
Pubmed	Studies of the murine homolog of the multiple endocrine neoplasia type 1 (MEN1) gene, men1.	MEN1 PAX6	2.40e-05	2	171	2	9893060
Pubmed	Genetic manipulation of cardiac Hsp72 levels does not alter substrate metabolism but reveals insights into high-fat feeding-induced cardiac insulin resistance.	HSPA1A HSPA1B	2.40e-05	2	171	2	25618331
Pubmed	Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury.	HSPA1A HSPA1B	2.40e-05	2	171	2	16679378
Pubmed	Inducible 70 kDa heat shock proteins protect embryos from teratogen-induced exencephaly: Analysis using Hspa1a/a1b knockout mice.	HSPA1A HSPA1B	2.40e-05	2	171	2	19639652
Pubmed	c-Abl and Arg tyrosine kinases regulate lysosomal degradation of the oncoprotein Galectin-3.	ABL1 ABL2	2.40e-05	2	171	2	20150913
Pubmed	Effect of mutation of amino acids 246-251 (KRKHKK) in HSP72 on protein synthesis and recovery from hypoxic injury.	HSPA1A HSPA1B	2.40e-05	2	171	2	16100242
Pubmed	Role of the C-terminal region of mouse inducible Hsp72 in the recognition of peptide substrate for chaperone activity.	HSPA1A HSPA1B	2.40e-05	2	171	2	15498567
Pubmed	Biological activity of truncated C-terminus human heat shock protein 72.	HSPA1A HSPA1B	2.40e-05	2	171	2	21094186
Pubmed	Differential role for CD277 as a co-regulator of the immune signal in T and NK cells.	BTN3A2 BTN3A1	2.40e-05	2	171	2	21918970
Pubmed	The molecular basis for modulation of human Vγ9Vδ2 T cell responses by CD277/butyrophilin-3 (BTN3A)-specific antibodies.	BTN3A2 BTN3A1	2.40e-05	2	171	2	22846996
Pubmed	A dominant vimentin mutant upregulates Hsp70 and the activity of the ubiquitin-proteasome system, and causes posterior cataracts in transgenic mice.	VIM HSPA1B	2.40e-05	2	171	2	18940912
Pubmed	Geranylgeranylaceton induces heat shock protein 72 in skeletal muscle cells.	HSPA1A HSPA1B	2.40e-05	2	171	2	17482577
Pubmed	A carrier of both MEN1 and BRCA2 mutations: case report and review of the literature.	MEN1 BRCA2	2.40e-05	2	171	2	18036394
Pubmed	Structure and expression of an inducible HSP70-encoding gene from Mus musculus.	HSPA1A HSPA1B	2.40e-05	2	171	2	8076831
Pubmed	The 70 kDa heat shock protein protects against experimental traumatic brain injury.	HSPA1A HSPA1B	2.40e-05	2	171	2	23816752
Pubmed	Global Regulation of Differential Gene Expression by c-Abl/Arg Oncogenic Kinases.	ABL1 ABL2	2.40e-05	2	171	2	28555614
Pubmed	Loss of dendrite stabilization by the Abl-related gene (Arg) kinase regulates behavioral flexibility and sensitivity to cocaine.	ABL1 ABL2	2.40e-05	2	171	2	19805386
Pubmed	c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression.	ABL1 ABL2	2.40e-05	2	171	2	21892207
Pubmed	Structure of a new crystal form of human Hsp70 ATPase domain.	HSPA1A HSPA1B	2.40e-05	2	171	2	10216320
Interaction	TRIP10 interactions	ABL2 POLR1A POLD1 SHANK3 MEN1 RIN1 PAX6 HSPA1A HTT	3.12e-07	109	167	9	int:TRIP10
Cytoband	1q23-q24	MYOC TNN	1.37e-04	5	171	2	1q23-q24
Cytoband	Ensembl 112 genes in cytogenetic band chr2p11	POLR1A IGKV3D-20 IGKV3D-7 DNAH6 IGKV3-20 IGKV3-15	1.56e-04	213	171	6	chr2p11
GeneFamily	Butyrophilins\|V-set domain containing\|C2-set domain containing	BTN3A2 BTN3A1 BTN3A3	8.00e-05	15	104	3	458
GeneFamily	Membrane associated guanylate kinases\|PDZ domain containing\|Scribble complex	LLGL2 LLGL1	1.95e-04	4	104	2	1224
GeneFamily	Immunoglobulin kappa locus at 2p11.2	IGKV3D-20 IGKV3D-7 IGKV3-20 IGKV3-15	1.34e-03	83	104	4	351
Coexpression	GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_UP	DPP10 PCDHB15 LCN8 XDH PNPLA5 BDH1 INPP4B DUOX1 HEG1 ADSS2	7.45e-07	200	169	10	M4344
Coexpression	GSE22589_HEALTHY_VS_SIV_INFECTED_DC_UP	LRWD1 POLD1 ZNF862 TAMALIN LLGL1 BRCA2 NFIC HSPA1A HSPA1B	6.13e-06	199	169	9	M7798
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	CABLES2 P4HA2 PIGK ZZEF1 ERLIN1 IQGAP1 MEN1 ITPR3 TINAGL1 HEG1 SF3B3 WIZ NID1 UBIAD1 VCL HTT	9.28e-06	681	169	16	M5314
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	CABLES2 P4HA2 PIGK ZZEF1 ERLIN1 IQGAP1 MEN1 ITPR3 TINAGL1 HEG1 SF3B3 WIZ NID1 UBIAD1 VCL HTT	1.37e-05	703	169	16	MM1055
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CPAMD8 DPP10 XDH ADGRV1 TTPA INPP4B PROM2 LIPH SCNN1G	6.81e-08	195	171	9	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	facs-GAT-Fat-24m-Epithelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT7 KCNH8 FAM3B ADGRV1 BDH1 PTPRT LIPH KDF1	3.66e-07	173	171	8	98e464d9e6d6b69421e9e4041b638b6825247f60
ToppCell	facs-GAT-Fat-24m-Epithelial-epithelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT7 KCNH8 FAM3B ADGRV1 BDH1 PTPRT LIPH KDF1	3.66e-07	173	171	8	3e6f0a08eddfd61871f7a85acccf6d539af6ebda
ToppCell	facs-GAT-Fat-24m-Epithelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT7 KCNH8 FAM3B ADGRV1 BDH1 PTPRT LIPH KDF1	3.66e-07	173	171	8	815ba48a9222ea09ba8005e2d2f7c5addf118ad1
ToppCell	Adult-Epithelial-club_cell-D122\|Adult / Lineage, Cell type, age group and donor	CPAMD8 RHOBTB3 CAMSAP3 TTPA INPP4B PROM2 LIPH SCNN1G	4.55e-07	178	171	8	35a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GABRB3 CACNA1A KRT7 DPP10 FAM3B SLC8A2 PROM2 SCN2A	4.95e-07	180	171	8	57689ccbbd44c0e78e061edd87d3102c5f2dcc9a
ToppCell	Globus_pallidus-Endothelial\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	VIM ECM2 IL17RC IQGAP1 TINAGL1 LLGL2 NID1 DOCK6	7.16e-07	189	171	8	ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CPAMD8 DPP10 XDH ADGRV1 TTPA INPP4B LIPH SCNN1G	7.75e-07	191	171	8	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	Calu_3\|World / Cell line, Condition and Strain	KRT7 ITPR3 TINAGL1 LLGL2 LIPH XAF1 HSPA1A HSPA1B	1.10e-06	200	171	8	a549aa08aeefe905653266dae3936094ff55f8e4
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	CPAMD8 TAMALIN SHANK3 HEG1 HMCN1 FGD5 NDRG4	4.00e-06	168	171	7	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	AT1_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	P4HA2 KRT7 TINAGL1 LLGL2 HSPA1A HSPA1B VCL	4.85e-06	173	171	7	b29816427428c7053017477f59b828bf1357f3b2
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE COL12A1 ADGRV1 PTPRT BLK HMCN1 WDR72	5.23e-06	175	171	7	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNH8 LCN8 BLK IGKV3D-20 IGKV3-20 IGKV3-15 CNR2	5.85e-06	178	171	7	107dae8b00c4257697a63700e72bb434cdb8406f
ToppCell	BAL-Mild-Lymphocyte-B\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	CACNA1A KCNH8 LCN8 BLK IGKV3-20 IGKV3-15 CNR2	6.53e-06	181	171	7	700adfb41e4e377530f0dd31be89e12f109f3469
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KRT7 CPAMD8 XDH TTPA INPP4B LIPH SCNN1G	6.77e-06	182	171	7	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	Mild-Lymphoid-B-\|Mild / Condition, Lineage, Cell class and cell subclass	CACNA1A KCNH8 LCN8 BLK IGKV3-20 IGKV3-15 CNR2	7.02e-06	183	171	7	b5740f05a4dcdbbf24f7bf7a3f57ac01a5e75f60
ToppCell	Mild-Lymphoid-B\|Mild / Condition, Lineage, Cell class and cell subclass	CACNA1A KCNH8 LCN8 BLK IGKV3-20 IGKV3-15 CNR2	7.02e-06	183	171	7	9b64d2d143525e6f48a191facfd101462ff36324
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNA1A KCNH8 LCN8 BLK IGKV3-20 IGKV3-15 CNR2	7.27e-06	184	171	7	64bede8db709fd32f40c03265b96f0b12155bb8a
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNA1A KCNH8 LCN8 BLK IGKV3-20 IGKV3-15 CNR2	7.27e-06	184	171	7	3f8a359e40bebe58545f708682e5e5d1b70cf5cb
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells-Pre-B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMEM243 LCN8 BLK ACSM3 SLC9A7 IGKV3-20 CNR2	7.53e-06	185	171	7	0fa7970709dc957dea95fabbd83263a0335babd5
ToppCell	BAL-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	CACNA1A KCNH8 LCN8 BLK IGKV3-20 IGKV3-15 CNR2	7.53e-06	185	171	7	609080adb2cfb105bb7b8efb617553833299f371
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	CPAMD8 TAMALIN SHANK3 HEG1 HMCN1 FGD5 NDRG4	7.80e-06	186	171	7	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE CACNA1A TBATA FAT2 SCN2A PAX6 BSN	8.08e-06	187	171	7	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	Frontal_cortex-Endothelial\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	VIM ECM2 IL17RC IQGAP1 TINAGL1 NID1 DOCK6	8.36e-06	188	171	7	a43392dbd10fc7dbfb31be39b8af8a7ea121c894
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Adult / Lineage, Cell type, age group and donor	TAMALIN SHANK3 FGD5 DOCK6 HSPA1A HSPA1B NDRG4	8.36e-06	188	171	7	e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 TAMALIN SHANK3 ITPR3 HEG1 XAF1 FGD5	8.66e-06	189	171	7	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	CPAMD8 TAMALIN SHANK3 HEG1 HMCN1 FGD5 NDRG4	8.66e-06	189	171	7	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	10x5'-blood-Lymphocytic_B\|blood / Manually curated celltypes from each tissue	KCNH8 BLK ACSM3 SLC9A7 IGKV3-20 IGKV3-15 CNR2	8.66e-06	189	171	7	9837dca502c9a7f42efb0bc74f3e88e7461e7dc8
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A FAT2 SCN2A PAX6 BSN NDRG4 EPHA8	8.66e-06	189	171	7	f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TAMALIN SHANK3 TINAGL1 LYPD5 ZNRF1 FGD5 NDRG4	8.96e-06	190	171	7	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	CPAMD8 DPP10 ADGRV1 TTPA INPP4B LIPH SCNN1G	8.96e-06	190	171	7	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CPAMD8 TAMALIN SHANK3 FGD5 DOCK6 HSPA1A HSPA1B	8.96e-06	190	171	7	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMEM243 LCN8 BLK ACSM3 SLC9A7 IGKV3-20 CNR2	8.96e-06	190	171	7	e1af324b4522045875fb64766cf118cd7b41704a
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZZEF1 PABIR2 GGT7 HEG1 NFIC VCL HTT	9.27e-06	191	171	7	cadb7a9de16f4bb21606de0e25cddd2d748c7f0b
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	CPAMD8 XDH ADGRV1 TTPA INPP4B LIPH SCNN1G	9.92e-06	193	171	7	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 TAMALIN SHANK3 HEG1 XAF1 FGD5 NDRG4	9.92e-06	193	171	7	0b328f725f6feba263783eaca60c142e80df90f3
ToppCell	Club_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	KRT7 RHOBTB3 MUC16 INPP4B FAT2 PROM2 SCNN1G	9.92e-06	193	171	7	6582c0367052b9d10fb629c383ee0c55872afd2d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	VIM MYOC TAMALIN SHANK3 HEG1 XAF1 FGD5	9.92e-06	193	171	7	cc355b2ed6510619cad969ae074126d7c8db784d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 TAMALIN SHANK3 HEG1 XAF1 FGD5 NDRG4	9.92e-06	193	171	7	6a623acd1adad9a78eddc32ffedb16352ad3fdfa
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS-RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KRT7 CPAMD8 DPP10 INPP4B PROM2 LIPH SCNN1G	1.03e-05	194	171	7	a58841b34efe673671a9a059238e044a7254b279
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KRT7 CPAMD8 DPP10 INPP4B PROM2 LIPH SCNN1G	1.03e-05	194	171	7	0cd4363627acd419e00d6d32f6dce10430aa6487
ToppCell	Bronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KRT7 MUC16 TTPA GLYATL1 PROM2 LIPH BSN	1.06e-05	195	171	7	fc2a1d84b3d013e5cb9e7b9cdd740e4010897d20
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MXRA5 COL12A1 ECM2 INPP4B TINAGL1 NID1 VCL	1.06e-05	195	171	7	d760d1423f9a8a373fe7b250ea9b1d67a0c0059f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRHDE CACNA1A CUX2 KCNH8 CSMD2 PTPRT SCN2A	1.06e-05	195	171	7	787e95fb59c40bba784544b662fac37606ae1427
ToppCell	Healthy/Control-B_naive\|Healthy/Control / Disease group and Cell class	KCNH8 TMEM243 TAMALIN BLK ACSM3 SLC9A7 CNR2	1.10e-05	196	171	7	e92d2c814d2dcb049f3e455fe66fd40898b3524d
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Club\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	KRT7 CPAMD8 CAMSAP3 ADGRV1 TTPA LIPH SCNN1G	1.10e-05	196	171	7	4e4c632db73b1340d80bf40a7657cb4821084d3c
ToppCell	Healthy/Control-B_naive\|World / Disease group and Cell class	KCNH8 TMEM243 TAMALIN BLK ACSM3 SLC9A7 CNR2	1.10e-05	196	171	7	ec935a4e16495c87b17070eb13c1e28bdb64e7ee
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KCNH8 TMEM243 LCN8 TAMALIN BLK ACSM3 SLC9A7	1.13e-05	197	171	7	20dcb006df86bbeb4a2e598aae8f15b349c7b6a6
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KCNH8 LCN8 BLK IGKV3D-20 IGKV3-20 IGKV3-15 CNR2	1.13e-05	197	171	7	9fe1b757f76c2d43d39aa9ac500eaba98723985c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TAMALIN SHANK3 HEG1 XAF1 FGD5 DOCK6 HSPA1A	1.17e-05	198	171	7	31ba87552be97c9b78c9e82f98e96699ccb19824
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TAMALIN SHANK3 HEG1 XAF1 FGD5 DOCK6 HSPA1A	1.17e-05	198	171	7	fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TAMALIN SHANK3 HEG1 XAF1 FGD5 DOCK6 HSPA1A	1.17e-05	198	171	7	0a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VIM CPAMD8 TAMALIN TINAGL1 HEG1 FGD5 NDRG4	1.17e-05	198	171	7	8a55589b9244283e4b0b423a4a6d6202e8e0fec9
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KRT7 KCNH8 ADGRV1 ITPR3 DUOX1 LLGL2 RNF212B	1.21e-05	199	171	7	f8846446ebbc4948cdc69640782db1358bbdc486
ToppCell	Parenchyma_COVID-19-Epithelial-TX-AT1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	KRT7 KCNH8 ADGRV1 ITPR3 DUOX1 LLGL2 RNF212B	1.21e-05	199	171	7	fe9f5bc317be0c35bd96311bf0b3c7b91d98acc5
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	KRT7 KCNH8 ADGRV1 ITPR3 DUOX1 LLGL2 RNF212B	1.21e-05	199	171	7	3e35ee426ef06f9af568c37349b62dd1ee9b97ea
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-B-B_naive\|Leuk-UTI / Disease, condition lineage and cell class	KCNH8 LCN8 BLK KLHL34 IGKV3-20 IGKV3-15 CNR2	1.21e-05	199	171	7	f93efc7d4c4a40d65fa10b53a2da6d961930f7d2
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-B-B_naive\|COVID-19_Severe / Disease, condition lineage and cell class	KCNH8 TMEM243 LCN8 TAMALIN BLK SLC9A7 CNR2	1.25e-05	200	171	7	5ba9c541fa356d34f392a63274dcd7bfb844cbb6
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ABL2 TAMALIN SHANK3 TINAGL1 HEG1 FGD5 RNF212B	1.25e-05	200	171	7	5ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRHDE VIM COL12A1 MYOC ECM2 HMCN1 NID1	1.25e-05	200	171	7	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MUC16 DUOX1 FAT2 LLGL2 CPLANE1 HSPA1A HSPA1B	1.25e-05	200	171	7	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POLD1 INPP4B BLK GGH SLC9A7 CNR2	1.84e-05	142	171	6	a88bf4bcc80206b16dcc504cc19a3380d01e34a4
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Macc1_Lrg1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CUX2 TAMALIN KCNH4 RIN1 XAF1 HSPA1B	1.84e-05	142	171	6	d08e1880425d285c4433014fe0242ac7ff7734af
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1A CUX2 DPP10 CSMD2 PTPRT RNF212B	2.33e-05	148	171	6	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CUX2 TAMALIN KCNH4 RIN1 XAF1 HSPA1B	2.33e-05	148	171	6	d5cace5605bff2bb8248fadb51f2dad7539930ba
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CUX2 SLC7A11 SLC9A7 HSPA1A HSPA1B CNR2	2.51e-05	150	171	6	57f21ad380fd1350a2c25d75ad8c3b763ded53ec
ToppCell	Transplant_Alveoli_and_parenchyma-Immune-B_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	KCNH8 LCN8 BLK IGKV3D-20 IGKV3-15 CNR2	2.71e-05	152	171	6	66f9190de155251a63a7a669374f342a75d22ea0
ToppCell	Healthy-B_cell\|Healthy / disease group, cell group and cell class	CAMSAP3 LCN8 BLK BRCA2 PROM2 CNR2	2.81e-05	153	171	6	7f82cd61b3f1ebaee3e4bbf68ba858a67c2065e7
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A11 GGH TBATA FOXRED2 ASPRV1 HSPA1A	3.36e-05	158	171	6	90ca742739a208d457db087655ba3d1c18a9da57
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GABRB3 CACNA1A KCNH8 DPP10 SCN2A BSN	3.48e-05	159	171	6	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VIM SLC7A11 GGH TBATA FOXRED2 HSPA1A	3.61e-05	160	171	6	8dae9b0cf90a09acb196223f45a14680102630b2
ToppCell	343B-Epithelial_cells-Epithelial-H_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TTPA TINAGL1 GGH FAT2 HMCN1 IGKV3-20	3.74e-05	161	171	6	da9eecf919866a9c579d7a707a996cf335213134
ToppCell	343B-Epithelial_cells-Epithelial-H_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TTPA TINAGL1 GGH FAT2 HMCN1 IGKV3-20	3.74e-05	161	171	6	d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SHANK3 HEG1 XAF1 FGD5 DOCK6 NDRG4	4.00e-05	163	171	6	73c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO9B ADGRV1 GNMT INPP4B HSPA1B CNR2	4.14e-05	164	171	6	b77995958c938e10a526118f75d78cee72e0b207
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1A CUX2 DPP10 CSMD2 PTPRT RNF212B	4.58e-05	167	171	6	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CUX2 RASA1 INPP4B MAP3K4 CD5 MLIP	4.58e-05	167	171	6	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B0\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ABL1 FAM3B INPP4B BLK CD5 LLGL1	4.90e-05	169	171	6	89b5452e0d8d058648a1d2659f1611fd6aebc6b6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PCDHB15 SHANK3 C17orf58 HEG1 XAF1	4.90e-05	169	171	6	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TNN SCN2A LYPD5 DMRTA1 HSPA1A IGKV3-15	4.90e-05	169	171	6	225aec04ba762d4c55885257de03a65b63503fbb
ToppCell	367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TNN SCN2A LYPD5 DMRTA1 HSPA1A IGKV3-15	4.90e-05	169	171	6	278960f940b646a788360b1c84d641a8d169896b
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHB15 TINAGL1 RIN1 HEG1 FGD5 NDRG4	5.06e-05	170	171	6	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC63 MXRA5 BICD1 FAT2 SCN2A SCNN1G	5.06e-05	170	171	6	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHB15 TINAGL1 RIN1 HEG1 FGD5 NDRG4	5.06e-05	170	171	6	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	COVID-19_Mild-PLT_2\|COVID-19_Mild / Disease Group and Platelet Clusters	SLAMF8 ABL1 ABL2 RNF25 TSC2 ATIC	5.58e-05	173	171	6	d11705e56b6b21eec963ea224717f27680c781ed
ToppCell	AT1_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	KRT7 COL12A1 PNPLA5 HEG1 LLGL2 VCL	5.58e-05	173	171	6	3afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	KRT7 ADGRV1 ITPR3 DUOX1 PROM2 KDF1	5.76e-05	174	171	6	edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KRT7 DPP10 PCDHB15 CSMD2 SCNN1G WDR72	5.76e-05	174	171	6	cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)\|367C / Donor, Lineage, Cell class and subclass (all cells)	KRT7 ADGRV1 ITPR3 DUOX1 PROM2 KDF1	5.76e-05	174	171	6	65539f69100db0b7d90b1b39ee15ab8281f86461
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KRT7 DPP10 PCDHB15 CSMD2 SCNN1G WDR72	5.76e-05	174	171	6	b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KRT7 DPP10 PCDHB15 CSMD2 SCNN1G WDR72	5.76e-05	174	171	6	71730503be3d9c839c4c9e950145e2101d682a1c
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	KRT7 DPP10 PCDHB15 CSMD2 SCNN1G WDR72	5.76e-05	174	171	6	ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCell	wk_15-18-Hematologic_Lymphocytic-B-Pro-B/Pre-B_transition\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	P4HA2 TMEM243 BLK ACSM3 SLC9A7 CNR2	5.76e-05	174	171	6	183ff6b93b7fbe43d83e12427e234bd7d8745961
ToppCell	Adult-Endothelial-endothelial_cell_of_vein\|Adult / Lineage, Cell type, age group and donor	SHANK3 TINAGL1 HEG1 FGD5 DOCK6 NDRG4	6.13e-05	176	171	6	043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCell	pdx-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CUX2 ABL2 FAM3B BDH1 ACSM3 MLIP	6.13e-05	176	171	6	1e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D3\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	HECTD4 TINAGL1 SLC9A7 HSPA1A HSPA1B DNAH6	6.13e-05	176	171	6	bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RHOBTB3 LLGL2 HMCN1 PROM2 KCNJ10 SCN2A	6.33e-05	177	171	6	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNH8 LCN8 BLK IGKV3-20 IGKV3-15 CNR2	6.53e-05	178	171	6	6f50e2ee66bd9dc12fd3c9ea70e6d50ff76b02e8
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNH8 LCN8 BLK IGKV3-20 IGKV3-15 CNR2	6.53e-05	178	171	6	b132605f237e766a21042b9a65a564d64c4fec10
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNH8 LCN8 BLK IGKV3-20 IGKV3-15 CNR2	6.53e-05	178	171	6	99cd5e517855f1a2d6d75fb2d439751f884862c1
Drug	Glibenclamide [10238-21-8]; Up 200; 8uM; MCF7; HT_HG-U133A	SLAMF8 MGAM MYOC ZNF862 IL17RC XRCC4 DUOX1 HEG1 NID1 XAF1	2.02e-06	198	166	10	3163_UP
Drug	Oxyphenbutazone [129-20-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A	P4HA2 ABL2 ZNF862 XDH XRCC4 SLC7A11 BTN3A1 EHBP1L1 DOCK6	1.11e-05	190	166	9	6844_UP
Drug	fullerene C60	LRRC63 ATXN2L ABL1 ABL2 MYO9B XDH BDH1 SHANK3 INPP4B MAP3K4 CUEDC1 BICD1 ITPR3 TG IVD TBATA EHBP1L1 FOXRED2 LLGL2 LLGL1 FHOD1 HPS1 HACL1 PAX6 BSN HSPA1A EPHA8	1.15e-05	1498	166	27	ctd:C069837
Drug	Proglumide [6620-60-6]; Down 200; 12uM; MCF7; HT_HG-U133A	VIM ATXN2L ZNF862 AXIN1 EHBP1L1 SF3B3 SND1 FHOD1 NDRG4	1.32e-05	194	166	9	3861_DN
Drug	Glibenclamide [10238-21-8]; Up 200; 8uM; HL60; HG-U133A	CACNA1A MYOC MOSPD3 ZZEF1 TSFM LLGL1 WIZ DDX54 DOCK6	1.43e-05	196	166	9	1546_UP
Drug	staurosporine; Down 200; 0.01uM; MCF7; HG-U133A	MAN2A2 RHOBTB3 ZZEF1 PTPRT AXIN1 BICD1 CD5 WIZ NDRG4	1.43e-05	196	166	9	425_DN
Drug	Epitiostanol [2363-58-8]; Down 200; 13uM; PC3; HT_HG-U133A	ABL2 ZNF862 IL17RC XRCC4 BTN3A2 AXIN1 BTN3A3 HEG1 WIZ	1.43e-05	196	166	9	4204_DN
Disease	Glaucoma	CPAMD8 MYOC TDRD7	1.36e-05	9	163	3	C0017601
Disease	Cataract	VIM CPAMD8 TDRD7 PAX6	5.14e-05	37	163	4	C0086543
Disease	paranoid schizophrenia (is_implicated_in)	PAX6 HSPA1A	9.07e-05	3	163	2	DOID:1229 (is_implicated_in)
Disease	urate measurement	P4HA2 CUX2 HECTD4 XDH ADGRV1 BTN3A2 PTPRT INPP4B TSFM MEN1 ACSM3 LIPH NFIC NID1 KDF1	1.40e-04	895	163	15	EFO_0004531
Disease	anxiety disorder (implicated_via_orthology)	TSC2 SCN2A CNR2	2.36e-04	22	163	3	DOID:2030 (implicated_via_orthology)
Disease	sodium measurement	CUX2 MEN1 MLIP SCN2A WDR72	2.74e-04	103	163	5	EFO_0009282
Disease	graft-versus-host disease (biomarker_via_orthology)	HSPA1A HSPA1B	3.00e-04	5	163	2	DOID:0081267 (biomarker_via_orthology)
Disease	neuroblastoma (implicated_via_orthology)	LLGL2 LLGL1	3.00e-04	5	163	2	DOID:769 (implicated_via_orthology)
Disease	Pseudoaphakia	VIM TDRD7 PAX6	3.08e-04	24	163	3	C0524524
Disease	Lens Opacities	VIM TDRD7 PAX6	3.08e-04	24	163	3	C1510497
Disease	pancreatic ductal carcinoma (is_marker_for)	KRT7 TSC2 MEN1 PAX6	3.67e-04	61	163	4	DOID:3587 (is_marker_for)
Disease	Lennox-Gastaut syndrome	GABRB3 CUX2	4.48e-04	6	163	2	C0238111
Disease	coffee consumption measurement	CUX2 C17orf58 BICD1 NCOR2 CD5 SND1	5.41e-04	182	163	6	EFO_0006781
Disease	hip circumference	ATXN2L MXRA5 DPP10 BTN3A2 PTPRT HMCN1 LIPH NFIC	6.10e-04	338	163	8	EFO_0005093
Disease	Akinetic Petit Mal	GABRB3 CACNA1A	6.25e-04	7	163	2	C0001890
Disease	Epilepsy, Absence, Atypical	GABRB3 CACNA1A	6.25e-04	7	163	2	C0751124
Disease	Absence Seizure Disorder	GABRB3 CACNA1A	6.25e-04	7	163	2	C4553705
Disease	Juvenile Absence Epilepsy	GABRB3 CACNA1A	6.25e-04	7	163	2	C4317339
Disease	Childhood Absence Epilepsy	GABRB3 CACNA1A	6.25e-04	7	163	2	C4281785
Disease	Epilepsy, Minor	GABRB3 CACNA1A	6.25e-04	7	163	2	C4552765
Disease	Absence Epilepsy	GABRB3 CACNA1A	6.25e-04	7	163	2	C0014553
Disease	hereditary ataxia (implicated_via_orthology)	CACNA1A PITRM1	6.25e-04	7	163	2	DOID:0050951 (implicated_via_orthology)
Disease	body weight	GABRB3 ATXN2L MGAM CUX2 POLR1A HECTD4 IL17RC ADGRV1 ZZEF1 BTN3A2 PTPRT AXIN1 BICD1 MLIP NFIC DMRTA1 UBIAD1	6.39e-04	1261	163	17	EFO_0004338
Disease	Autistic Disorder	GABRB3 XDH TSC2 TRRAP SHANK3 SND1 PAX6	6.45e-04	261	163	7	C0004352
Disease	Anterior segment dysgenesis	CPAMD8 PAX6	8.31e-04	8	163	2	cv:C1862839
Disease	gamma-glutamyl hydrolase measurement	TTPA GGH	8.31e-04	8	163	2	EFO_0801616
Disease	Breast Carcinoma	VIM ABL1 BTN3A2 INPP4B LLGL2 LLGL1 BRCA2 FGD5 HSPA1B CNR2	8.57e-04	538	163	10	C0678222
Disease	Malignant neoplasm of breast	VIM ABL1 NOA1 PCDHB15 MED14 XDH BTN3A2 INPP4B CHRND LLGL2 LLGL1 BRCA2 FGD5 HSPA1B CNR2	9.42e-04	1074	163	15	C0006142
Disease	small cell lung carcinoma	IL17RC ADGRV1 BTN3A1 BRCA2	1.02e-03	80	163	4	EFO_0000702
Disease	Adult Hepatocellular Carcinoma	TSC2 AXIN1	1.06e-03	9	163	2	C0279607
Disease	Major depression, single episode	HSPA1A HSPA1B	1.06e-03	9	163	2	C0024517
Disease	Generalized Epilepsy with Febrile Seizures Plus	ADGRV1 SCN2A	1.06e-03	9	163	2	C3502809
Disease	macrophage colony stimulating factor measurement	ABL1 SCNN1G EPHA8	1.12e-03	37	163	3	EFO_0008217
Disease	creatinine measurement	P4HA2 CUX2 ADGRV1 GGT7 BLK TINAGL1 DUOX1 ACSM3 MLIP SND1 LIPH BSN RPL3L WDR72	1.30e-03	995	163	14	EFO_0004518
Disease	medulloblastoma (is_implicated_in)	TSC2 BRCA2	1.33e-03	10	163	2	DOID:0050902 (is_implicated_in)
Disease	autism spectrum disorder (implicated_via_orthology)	GABRB3 TSC2 SHANK3 ITPR3 SCN2A	1.59e-03	152	163	5	DOID:0060041 (implicated_via_orthology)
Disease	aspartate aminotransferase measurement	VIM P4HA2 CUX2 HECTD4 XDH ALKBH5 INPP4B ERLIN1 BLK NCOR2 SND1 DMRTA1 UBIAD1	1.59e-03	904	163	13	EFO_0004736
Disease	kidney cancer (implicated_via_orthology)	LLGL2 LLGL1	1.61e-03	11	163	2	DOID:263 (implicated_via_orthology)
Disease	spleen volume	MYO9B HECTD4 DMRTA1	1.74e-03	43	163	3	EFO_0600047
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	ATXN2L ITPR3	1.93e-03	12	163	2	DOID:1441 (implicated_via_orthology)
Disease	alcohol consumption measurement, alcohol drinking	CUX2 HECTD4	1.93e-03	12	163	2	EFO_0004329, EFO_0007878
Disease	Congenital Hypothyroidism	CDCA8 TG	2.27e-03	13	163	2	C0010308
Disease	hypothyroidism (implicated_via_orthology)	TG DUOX1	2.27e-03	13	163	2	DOID:1459 (implicated_via_orthology)
Disease	squamous cell lung carcinoma	XRCC4 BTN3A2 ERLIN1 BTN3A3 BRCA2	2.28e-03	165	163	5	EFO_0000708
Disease	Pancreatic Neoplasm	TSC2 MEN1 BRCA2 CNR2	2.33e-03	100	163	4	C0030297
Disease	Malignant neoplasm of pancreas	TSC2 MEN1 BRCA2 CNR2	2.51e-03	102	163	4	C0346647
Disease	developmental disorder of mental health (implicated_via_orthology)	GABRB3 GIGYF1 NCOR2	2.53e-03	49	163	3	DOID:0060037 (implicated_via_orthology)
Disease	melanoma	ABL1 TRRAP RIN1 BRCA2 PAX6 HSPA1A	2.63e-03	248	163	6	C0025202
Disease	asymmetric dimethylarginine measurement	ZZEF1 HACL1	2.64e-03	14	163	2	EFO_0010463
Disease	congenital hypothyroidism (implicated_via_orthology)	TG DUOX1	2.64e-03	14	163	2	DOID:0050328 (implicated_via_orthology)
Disease	Mammary Carcinoma, Human	VIM ABL1 BTN3A2 LLGL2 LLGL1 BRCA2 FGD5 HSPA1B CNR2	2.67e-03	525	163	9	C4704874
Disease	Mammary Neoplasms, Human	VIM ABL1 BTN3A2 LLGL2 LLGL1 BRCA2 FGD5 HSPA1B CNR2	2.67e-03	525	163	9	C1257931
Disease	Mammary Neoplasms	VIM ABL1 BTN3A2 LLGL2 LLGL1 BRCA2 FGD5 HSPA1B CNR2	2.74e-03	527	163	9	C1458155
Disease	platelet storage pool deficiency (implicated_via_orthology)	SLC7A11 HPS1	3.04e-03	15	163	2	DOID:2223 (implicated_via_orthology)
Disease	low density lipoprotein cholesterol measurement, response to selective serotonin reuptake inhibitor	CSMD2 MLIP	3.04e-03	15	163	2	EFO_0004611, EFO_0005658
Disease	Condition, Preneoplastic	ABL1 DPP10 TSC2 DDX54	3.29e-03	110	163	4	C0282313
Disease	Precancerous Conditions	ABL1 DPP10 TSC2 DDX54	3.29e-03	110	163	4	C0032927
Disease	Ciliopathies	TSC2 ADGRV1 SCNN1G CPLANE1	3.29e-03	110	163	4	C4277690
Disease	plasminogen activator inhibitor 1 measurement	INPP4B MAP3K4 NFIC	3.34e-03	54	163	3	EFO_0004792
Disease	sexual dimorphism measurement	ATXN2L MGAM P4HA2 MYO9B TSC2 ZZEF1 FAM83C BTN3A2 C17orf58 GGT7 NCOR2 EHBP1L1 NFIC BSN	3.41e-03	1106	163	14	EFO_0021796
Disease	focal segmental glomerulosclerosis	SCNN1G DNAH6	3.46e-03	16	163	2	EFO_0004236
Disease	atherosclerosis (is_implicated_in)	VIM HSPA1A	3.46e-03	16	163	2	DOID:1936 (is_implicated_in)
Disease	Ischemic stroke, fibrinogen measurement	ATXN2L HECTD4 SHANK3	3.52e-03	55	163	3	EFO_0004623, HP_0002140
Disease	Schizophrenia	GABRB3 MYO9B XRCC4 CSMD2 TRRAP SHANK3 ADSS2 PAX6 FBXO45 HSPA1A HSPA1B CNR2	3.78e-03	883	163	12	C0036341
Disease	cancer (implicated_via_orthology)	CUX2 AXIN1 BLK LLGL2 LLGL1 BRCA2	3.85e-03	268	163	6	DOID:162 (implicated_via_orthology)
Disease	ocular hypertension (biomarker_via_orthology)	MYOC ACSM3	3.91e-03	17	163	2	DOID:9282 (biomarker_via_orthology)
Disease	fibrinogen measurement, factor VII measurement	ATXN2L HECTD4 SHANK3	4.09e-03	58	163	3	EFO_0004619, EFO_0004623
Disease	Atherosclerosis	TTPA HSPA1B CNR2	4.29e-03	59	163	3	C0004153
Disease	Atherogenesis	TTPA HSPA1B CNR2	4.29e-03	59	163	3	C1563937
Disease	Febrile seizure (within the age range of 3 months to 6 years)	SCN2A BSN	4.38e-03	18	163	2	HP_0002373
Disease	Pancreatic carcinoma	INPP4B BRCA2	4.88e-03	19	163	2	C0235974
Disease	systemic lupus erythematosus (is_implicated_in)	VIM BLK HSPA1A	4.93e-03	62	163	3	DOID:9074 (is_implicated_in)
Disease	carcinoma (implicated_via_orthology)	BLK LLGL2 LLGL1	5.39e-03	64	163	3	DOID:305 (implicated_via_orthology)
Disease	Adenocarcinoma of prostate	AXIN1 BRCA2	5.40e-03	20	163	2	C0007112

Protein segments in the cluster

Peptide	Gene	Start	Entry
TKSGVVVRLYARPDA	TRHDE	346	Q9UKU6
SVLGPKARRLDDYSL	CACNA1A	2126	O00555
PGALVRRSSSLGYIS	CHRND	371	Q07001
APYRGRTSILRDGIT	BTN3A3	91	O00478
LNGDYRTPTLRKGES	BICD1	296	Q96G01
LEVRDGRTYSAPLIG	CSMD2	806	Q7Z408
FARSPGADLSLEKYR	ACOX3	61	O15254
GPVSRSAAEYLLSSL	ABL2	176	P42684
APYRGRTSILRDGIT	BTN3A1	91	O00481
IGRRTYASAAEPVGS	BDH1	41	Q02338
LPVRRGSVTVLSGYA	ALKBH5	246	Q6P6C2
YSDIRTGRESSLPSK	ERLIN1	316	O75477
TTPGGTRIIYDRKFL	EIF4EBP3	31	O60516
SPGERYLSLSFTRLG	ADGRV1	531	Q8WXG9
LARATQGRDYIPASG	ADGRV1	2031	Q8WXG9
SYRVLDAGDPTSRGL	CD5	326	P06127
SDRGLLSRPYASVSP	CUX2	791	O14529
SPARGLLGSRLSKIY	CAMSAP3	1031	Q9P1Y5
SPRGRQLYSASTEGL	DPP10	446	Q8N608
LRPGASDLTGSFRLY	DPM1	176	O60762
GRESPSLASREGKYI	ATXN2L	336	Q8WWM7
PVIYALRSGEIRSSA	CNR2	296	P34972
KTLSALRSPDVGLYG	IQGAP1	641	P46940
TTLPRAAGRETKYAN	MLIP	301	Q5VWP3
LAILKESPSRYQGSR	RNF212B	131	A8MTL3
GYAILLAVPGSSDSR	RBM15	856	Q96T37
SGSYLIRESDRRPGS	RASA1	201	P20936
RYSLGPSLRRGHEVS	ITPR3	1841	Q14573
IEKAVRSSIYGRPGA	HACL1	151	Q9UJ83
DASGVALRPLYKLST	LLGL1	461	Q15334
KSAVRDVRYGPESLS	LRWD1	171	Q9UFC0
VDLSLYPREGGVSSR	MEN1	101	O00255
SKGSRLQRLVPASYA	DUOX1	46	Q9NRD9
RGRDLGLPSYTKARA	DUOX1	426	Q9NRD9
GLPSYTKARAALGLS	DUOX1	431	Q9NRD9
YETGSIRPRAIGGSK	PAX6	61	P26367
YSGCRLTLLRPEKDG	MUC16	13216	Q8WXI7
RGLSPRESSLALNYA	NCOR2	1711	Q9Y618
GLVPADVLRRVYSGS	KLHL34	226	Q8N239
DVLRRVYSGSGLVLP	KLHL34	231	Q8N239
LSDSYSHLSGRPIRK	GIGYF1	866	O75420
VASPSGLRDSTVRYG	KCNJ10	336	P78508
SALGYSPSLRILAIG	LLGL2	36	Q6P1M3
RLLIYDASSRATGIP	IGKV3D-20	66	A0A0C4DH25
GTNVYGILRAPRAAS	GPAA1	126	O43292
SSSLYGLGASRPRVA	KRT7	36	P08729
SAGPGLLKAYSIRTA	KRT7	446	P08729
LIYGASTRATGIPAR	IGKV3D-7	71	A0A0C4DH55
RPGDGLLRSSSSYVK	C17orf58	306	Q2M2W7
VRSALLALYTARPGG	INPP4B	466	O15327
LPALTYRTTGGVLDF	MGAM	2096	O43451
VRYISAPEKTGRGES	BSN	2701	Q9UPA5
GLRTPAAGERIYNIS	CDCA8	201	Q53HL2
RAGRSGTAYSLVAPD	DDX54	431	Q8TDD1
SLRVFLVARTGSYPA	TSFM	6	P43897
LVARTGSYPAGSLLR	TSFM	11	P43897
PTAAAIAYGLDRTGK	HSPA1B	176	P0DMV9
EPSRLLRTYAGGAVI	FAM157A	221	C9JC47
ATLTRPGAEKTGYRV	FAT2	3241	Q9NYQ8
LALASRLGDPVYDST	GGT7	416	Q9UJ14
LTADTGLYLAARPGR	LCN8	151	Q6JVE9
TPFSYKALRRGGADT	NID1	311	P14543
KALRRGGADTYSVPS	NID1	316	P14543
IDALGSGAPTSQRRY	CUEDC1	156	Q9NWM3
TKSLEVGSYPILRAR	DCAF10	331	Q5QP82
SESPSSLIFYRDGKR	FGD5	716	Q6ZNL6
SLARSIPESLKVYGS	GLYATL1	16	Q969I3
TRVGSALKYEALRAP	EHBP1L1	891	Q8N3D4
LQGAEPSRLLRTYAG	FAM157C	221	P0CG43
RILKESPSGYLRSGE	MYOC	226	Q99972
SVGGPSRRSAYIAAL	KCNH4	416	Q9UQ05
ATGAYPRLSLSFRLK	GABRB3	226	P28472
FSTGSLIGPRYKLRI	LIPH	396	Q8WWY8
APLSIYSSRKAITEG	LRRC63	526	Q05C16
SSAPRGERSIAGISY	HEG1	521	Q9ULI3
YRTRSLGVAAEGLPD	GNMT	6	Q14749
STRTRGDGRKYPELV	PCDHB15	181	Q9Y5E8
LIRASYESKGSRGLF	FOXRED2	366	Q8IWF2
PAGYRRTATNGLVTL	HECTD4	2411	Q9Y4D8
YAKTDLAAVPASRGI	IVD	211	P26440
PLSSAAYSIRSIGER	FAM3B	36	P58499
AYSIRSIGERPVLKA	FAM3B	41	P58499
ELYRALAVSGGTLPR	TAMALIN	66	Q7Z6J2
LSVYRSVKRLGIPDS	PIGK	66	Q92643
LKLFRATPEDAGRYS	HMCN1	1416	Q96RW7
AAAAASPGYRLSTLI	MED14	41	O60244
SRDRSSPGALNVYVK	PTPRT	111	O14522
DTYRLDPGTISRGEL	P4HA2	141	O15460
YGGTLRRSSSAPLIH	PABIR2	16	Q7Z309
AEPSRLLRTYAGGAV	FAM157B	221	P0CG42
LASSRYLGPLKTRVD	DNAH6	1071	Q9C0G6
RAQRLGSSSVRPGLY	HTT	1341	P42858
ATLARGSGRPASLYL	DOCK6	861	Q96HP0
GSGRPASLYLARSKS	DOCK6	866	Q96HP0
RPSSDLYSLLTEGKR	BRCA2	2991	P51587
PGVDRYSLGTSLSRS	CPLANE1	1446	Q9H799
TSYRLKLSPADGTRG	COL12A1	2231	Q99715
PGGSVDLRRSDYAKV	GGH	96	Q92820
GGRLPSRVLELVFSY	FBXO45	36	P0C2W1
EASSRRGVPVYLLLA	FAM83C	191	Q9BQN1
LARSLVTGREGYVPS	BLK	96	P51451
TSTATPRRSDLDLGY	AXIN1	56	O15169
KSVYLLRSGFRLTPA	CPAMD8	621	Q8IZJ3
RATVSGLKPGTRYVF	EPHA8	496	P29322
RVGISPLRLAYSSAG	DMRTA1	431	Q5VZB9
SLARSIPESLKVYGS	GLYATL1B	16	A0A0U1RQE8
SSPGQRSISLRYEGR	ABL1	156	P00519
AVSTAARAYGRSRPK	C17orf98	21	A8MV24
APYRGRTSILRDGIT	BTN3A2	91	P78410
RGTLRLPSGCSLSYR	ECM2	311	O94769
RSGLAGRYPLSDFTL	MAN2A2	541	P49641
SLDTGYRAPVTLVRK	LYPD5	61	Q6UWN5
SGAGTLRPYLTEEAR	LSMEM2	56	Q8N112
GQAPRLLIYGASTRA	IGKV3-15	61	P01624
LLIYGASTRATGIPA	IGKV3-15	66	P01624
RLLIYGASSRATGIP	IGKV3-20	66	P01619
PTAAAIAYGLDRTGK	HSPA1A	176	P0DMV8
KLYSSSGPELRRSLF	FHOD1	126	Q9Y613
IYRLNFLTTAPSRGG	HPS1	481	Q92902
RASGSSIYPEAKARL	BLID	31	Q8IZY5
TREALKSLYGFPESR	SCNN1G	121	P51170
ARVTGVPLSYLLSRG	POLD1	536	P28340
LSYLSFEGATKRNRP	EXOSC3	141	Q9NQT5
SVLPYGEGLRISDLR	CABLES2	191	Q9BTV7
RSPRSGDGKLEALYV	KCNE1B	36	A0A087WTH5
YLELVSAALRRPGPS	NOA1	201	Q8NC60
LPSKASTRAARLGEY	IL17RC	491	Q8NAC3
RTYLGRSPLVSGDES	RHOBTB3	26	O94955
YVLTKCESGRGTRPR	MAP3K4	1076	Q9Y6R4
RGEIITPKTDTGRSY	SYTL5	196	Q8TDW5
DEGIRYRLGTIRPSS	TINAGL1	171	Q9GZM7
LLRRESSVGYRVPAG	RIN1	286	Q13671
GKRGYLTPTSAREHL	POLR1A	251	O95602
GYVATPRGLRSFKTI	RPL3L	91	Q92901
PRLLQGARRIYGSSS	PNPLA5	36	Q7Z6Z6
RHYSVTPLGTRSGLI	SMG1	2191	Q96Q15
YASIRAGRTLTPAGD	PITRM1	721	Q5JRX3
LKYSFPVGLRTSRTD	TMEM69	16	Q5SWH9
YGNREVLPSTRLGTL	SND1	766	Q7KZF4
GAKYSAETGRLIPAS	TBATA	181	Q96M53
YLKDRRLSGGAVPSA	NDRG4	291	Q9ULP0
GGIFRSTRYLPVTKE	WIZ	41	O95785
IGPVYSSKAARSGLR	ADSS2	166	P30520
GVALPRLQGEYRSLT	TDRD7	21	Q8NHU6
TTADAIARKLRPYGA	KDF1	356	Q8NAX2
LAYDLNPASTGLRRT	NFIC	256	P08651
RADDVILSSGYRIGP	ACSM3	476	Q53FZ2
SLRGEALGVYNRLSP	ASPRV1	141	Q53RT3
SEGKPRAISAYVRAG	CLLU1-AS1	61	Q5K130
TRTYGTSGLDNRPLF	TMEM243	6	Q9BU79
SGRDSSITRLPLAFY	SLC7A11	226	Q9UPY5
AIKYSEGDLPGSRSL	TTC30B	121	Q8N4P2
YSDSTGPREALSRLR	ZSCAN30	56	Q86W11
SYAKRRRLAGPSGLA	SHANK3	351	Q9BYB0
TYPVSLVAFKGGRRS	TNN	1036	Q9UQP3
APGLLDSLYGTVRRF	PROM2	56	Q8N271
AYRPGTRRESLGLES	RNF25	441	Q96BH1
TSSPRGDKAAYDILR	XAF1	251	Q6GPH4
RKALLSGAGPADVYT	XRCC4	71	Q13426
VGRKDITSILRAPAY	MOSPD3	126	O75425
LEGSRLTYEKRFSSP	SCN2A	541	Q99250
SVPARDYLIDGSRGI	VCL	101	P18206
SGLSKSIYPADGRVL	WDR72	286	Q3MJ13
SPGGVYATRSSAVRL	VIM	56	P08670
TAVALAAYKTGRPVR	XDH	811	P47989
LSISLGPGDRDVAYS	SLAMF8	186	Q9P0V8
LTPISAAYARARGAD	ATIC	296	P31939
SLTPVALGSALAYRS	UBIAD1	61	Q9Y5Z9
SRDPTGSKVLIYRIA	TTPA	106	P49638
PVTGDLSDTRTRYLG	SF3B3	681	Q15393
GAALSSRDVSGLPVY	ZNF839	576	A8K0R7
LHDKSSRLVRGYTGP	ZNF862	496	O60290
SRLVRGYTGPFKVET	ZNF862	501	O60290
AIKYSEGDLPGSRSL	TTC30A	121	Q86WT1
GLTISGYLRPARAEA	ZZEF1	696	O43149
LSPAETRGGAAKRYA	ZNF648	266	Q5T619
LRYGTPATSGRDKSL	SLC9A7	116	Q96T83
VLKSGVLSRRVSPGY	TG	1151	P01266
IGSGYTARETLRPLA	TRRAP	361	Q9Y4A5
LYTPASRGTGDSERA	ZNRF1	71	Q8ND25
YTISDSAPSRRGKRV	TSC2	1461	P49815
KLPVYTRTGSGAVRF	ZDHHC15	116	Q96MV8
TLGGPSIRSAYIAAL	KCNH8	411	Q96L42
ARGTVRLPYRTVDGT	SLC8A2	551	Q9UPR5
TSPRRTDVRYGGTLK	MXRA5	2151	Q9NR99
RPDIVALLRGSDSSY	MYO9B	656	Q13459