Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal protein binding	TPR FLII CTNNAL1 IQGAP2 TRPM7 SYNE1 LRRK2 OBSCN CLASP2 ITPRID2 JAKMIP3 SPAG5 PRUNE1 STIM1 FMNL3 SPTBN4 SETD2 DST BRCA1 KIF15 NDC80 BMP10 ARHGEF10 STARD9 SYNE2 MID1 CEP135 DLEC1 NIN	1.11e-07	1099	176	29	GO:0008092
GeneOntologyMolecularFunction	tubulin binding	TPR LRRK2 CLASP2 JAKMIP3 SPAG5 PRUNE1 STIM1 SETD2 DST BRCA1 KIF15 NDC80 STARD9 MID1 CEP135 DLEC1 NIN	2.59e-07	428	176	17	GO:0015631
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	RASGRP4 ARHGEF28 ABR PSD NUCB2 OBSCN PLEKHG1 ARHGEF10 RAPGEF3 HERC2 FGD3	6.72e-06	231	176	11	GO:0005085
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RALGAPA1 RASGRP4 ACAP1 ARHGEF28 ABR PSD IQGAP2 NUCB2 LRRK2 OBSCN PLEKHG1 ARHGAP6 ARHGEF10 RAPGEF3 HERC2 FGD3	1.13e-05	507	176	16	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RALGAPA1 RASGRP4 ACAP1 ARHGEF28 ABR PSD IQGAP2 NUCB2 LRRK2 OBSCN PLEKHG1 ARHGAP6 ARHGEF10 RAPGEF3 HERC2 FGD3	1.13e-05	507	176	16	GO:0030695
GeneOntologyMolecularFunction	microtubule binding	LRRK2 CLASP2 JAKMIP3 SPAG5 STIM1 DST KIF15 NDC80 STARD9 MID1 CEP135 NIN	1.94e-05	308	176	12	GO:0008017
GeneOntologyMolecularFunction	protein-membrane adaptor activity	TPR SYNE1 RB1CC1 SPTBN4 SYNE2	4.61e-05	45	176	5	GO:0043495
GeneOntologyMolecularFunction	cytoskeleton-nuclear membrane anchor activity	SYNE1 SYNE2	7.59e-04	5	176	2	GO:0140444
GeneOntologyMolecularFunction	microtubule plus-end binding	CLASP2 STIM1 DST	9.16e-04	22	176	3	GO:0051010
GeneOntologyMolecularFunction	actin filament binding	FLII CTNNAL1 IQGAP2 SYNE1 CLASP2 ITPRID2 FMNL3 SPTBN4	9.35e-04	227	176	8	GO:0051015
GeneOntologyMolecularFunction	actin binding	FLII CTNNAL1 IQGAP2 TRPM7 SYNE1 LRRK2 CLASP2 ITPRID2 FMNL3 SPTBN4 DST SYNE2	1.15e-03	479	176	12	GO:0003779
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	TPR SDCCAG8 CNTRL CLASP2 SPAG5 PRUNE1 FSIP2 SETD2 DST BRCA1 KIF15 NDC80 ARHGEF10 STARD9 GCC2 SYNE2 MID1 CEP135 SEPTIN1 TXNDC9 CEP152 ODAD3 PCNT NIN	7.58e-09	720	172	24	GO:0000226
GeneOntologyBiologicalProcess	organelle assembly	TPR FLII SYNE1 ZNF423 SDCCAG8 CNTRL LRRK2 OBSCN CLASP2 LRRTM1 ALPK1 RB1CC1 SPAG5 FSIP2 BRCA1 KIF15 NDC80 BMP10 ARHGEF10 MRPS2 STARD9 SYNE2 CEP135 SEPTIN1 CEP152 CPLANE1 ODAD3 PCNT	2.50e-07	1138	172	28	GO:0070925
GeneOntologyBiologicalProcess	microtubule-based process	TPR SDCCAG8 CNTRL CLASP2 SPAG5 PRUNE1 FSIP2 SETD2 DST BRCA1 KIF15 NDC80 ARHGEF10 STARD9 GCC2 SYNE2 MID1 CEP135 VPS13A SEPTIN1 TXNDC9 CEP152 ODAD3 PCNT NIN	2.46e-06	1058	172	25	GO:0007017
GeneOntologyBiologicalProcess	microtubule organizing center organization	SDCCAG8 CLASP2 BRCA1 KIF15 NDC80 ARHGEF10 GCC2 CEP135 CEP152 NIN	2.68e-06	179	172	10	GO:0031023
GeneOntologyBiologicalProcess	membraneless organelle assembly	TPR FLII OBSCN CLASP2 SPAG5 BRCA1 KIF15 NDC80 BMP10 ARHGEF10 MRPS2 STARD9 CEP135 SEPTIN1 CEP152	1.11e-05	475	172	15	GO:0140694
GeneOntologyBiologicalProcess	protein localization to organelle	TPR MIA3 SYNE1 ZNF423 LRRK2 OBSCN NBN SPAG5 GGA3 FSIP2 KPNA7 SETD2 BRCA1 GCC2 NFKBIA MID1 VPS13A EMC10 AKAP11 SEC63 CPLANE1 NIPBL GOLGB1	3.96e-05	1091	172	23	GO:0033365
GeneOntologyBiologicalProcess	spindle assembly	TPR CLASP2 SPAG5 KIF15 NDC80 ARHGEF10 STARD9 SEPTIN1	4.40e-05	153	172	8	GO:0051225
GeneOntologyBiologicalProcess	centrosome cycle	SDCCAG8 BRCA1 KIF15 NDC80 ARHGEF10 CEP135 CEP152 NIN	7.19e-05	164	172	8	GO:0007098
GeneOntologyBiologicalProcess	Golgi organization	SYNE1 LRRK2 CLASP2 ATP8B2 COG6 GCC2 TJAP1 GOLGB1	8.52e-05	168	172	8	GO:0007030
GeneOntologyBiologicalProcess	spindle organization	TPR CLASP2 SPAG5 KIF15 NDC80 ARHGEF10 STARD9 SEPTIN1 PCNT	1.14e-04	224	172	9	GO:0007051
GeneOntologyBiologicalProcess	regulation of organelle assembly	TPR SYNE1 SDCCAG8 LRRK2 LRRTM1 SPAG5 BRCA1 SYNE2 CEP135 ODAD3	1.26e-04	280	172	10	GO:1902115
GeneOntologyBiologicalProcess	actin cytoskeleton organization	FLII WASHC4 ABR IQGAP2 TRPM7 OBSCN CLASP2 SRCIN1 FMNL3 SPTBN4 ARHGAP6 FAT1 HMCN1 BMP10 ARHGEF10 RAPGEF3 AKAP11 FGD3	1.37e-04	803	172	18	GO:0030036
GeneOntologyBiologicalProcess	small GTPase-mediated signal transduction	RALGAPA1 RASGRP4 CTNNAL1 ARHGEF28 ABR PSD NUCB2 LRRK2 OBSCN PLEKHG1 ARHGAP6 ARHGEF10 RAPGEF3 FGD3	1.74e-04	538	172	14	GO:0007264
GeneOntologyBiologicalProcess	actomyosin structure organization	FLII IQGAP2 TRPM7 OBSCN CLASP2 ARHGAP6 BMP10 ARHGEF10 RAPGEF3	1.85e-04	239	172	9	GO:0031032
GeneOntologyBiologicalProcess	centrosome localization	SYNE1 CCDC141 SYNE2 NIN	2.00e-04	35	172	4	GO:0051642
GeneOntologyBiologicalProcess	negative regulation of nucleobase-containing compound transport	TPR RSC1A1	2.06e-04	3	172	2	GO:0032240
GeneOntologyBiologicalProcess	microtubule organizing center localization	SYNE1 CCDC141 SYNE2 NIN	2.23e-04	36	172	4	GO:0061842
GeneOntologyBiologicalProcess	actin filament-based process	FLII WASHC4 ABR IQGAP2 TRPM7 OBSCN CLASP2 SRCIN1 FMNL3 SPTBN4 ARHGAP6 FAT1 HMCN1 BMP10 ARHGEF10 RAPGEF3 SYNE2 AKAP11 FGD3	2.26e-04	912	172	19	GO:0030029
GeneOntologyBiologicalProcess	regulation of organelle organization	TPR FLII WASHC4 IQGAP2 SYNE1 SDCCAG8 LRRK2 NBN CLASP2 LRRTM1 SPAG5 PRUNE1 SPTBN4 ARHGAP6 BRCA1 NDC80 BMP10 ARHGEF10 RAPGEF3 SYNE2 MID1 CEP135 SLC35F6 ODAD3	3.31e-04	1342	172	24	GO:0033043
GeneOntologyBiologicalProcess	regulation of cytoskeleton organization	TPR FLII WASHC4 IQGAP2 CLASP2 SPAG5 PRUNE1 SPTBN4 ARHGAP6 BRCA1 BMP10 ARHGEF10 RAPGEF3 MID1	3.67e-04	579	172	14	GO:0051493
GeneOntologyCellularComponent	microtubule organizing center	FLII FAM184A TRAF5 SDCCAG8 CNTRL CLASP2 ALPK1 CCDC141 SPAG5 BRCA1 KIF15 NDC80 ARHGEF10 STARD9 MID1 CEP135 SEPTIN1 TXNDC9 AKAP11 CEP152 HERC2 ODAD3 PCNT NIN	4.46e-07	919	170	24	GO:0005815
GeneOntologyCellularComponent	centrosome	FLII FAM184A TRAF5 SDCCAG8 CNTRL CLASP2 ALPK1 CCDC141 SPAG5 BRCA1 KIF15 NDC80 ARHGEF10 MID1 CEP135 SEPTIN1 TXNDC9 AKAP11 CEP152 PCNT NIN	1.26e-06	770	170	21	GO:0005813
GeneOntologyCellularComponent	centriole	SDCCAG8 STARD9 CEP135 CEP152 HERC2 ODAD3 PCNT NIN	8.44e-05	172	170	8	GO:0005814
GeneOntologyCellularComponent	centriolar satellite	FLII FAM184A SDCCAG8 CNTRL SPAG5 MID1 PCNT	8.61e-05	128	170	7	GO:0034451
GeneOntologyCellularComponent	cell leading edge	NRBP1 PSD IQGAP2 TRPM7 CLASP2 SRCIN1 MTMR6 FAT1 DST RAPGEF3 SYNE2 FGD3	8.29e-04	500	170	12	GO:0031252
GeneOntologyCellularComponent	trans-Golgi network	LRRK2 CLASP2 SLC10A7 ATP8B2 GGA3 COG6 GCC2 TJAP1 DOP1A	9.26e-04	306	170	9	GO:0005802
GeneOntologyCellularComponent	cell cortex	NRBP1 IQGAP2 CLASP2 STIM1 SPTBN4 DST HMCN2 HMCN1 RAPGEF3 SEPTIN1	9.47e-04	371	170	10	GO:0005938
GeneOntologyCellularComponent	BRCA1-C complex	NBN BRCA1	9.65e-04	6	170	2	GO:0070533
GeneOntologyCellularComponent	Golgi apparatus subcompartment	NUCB2 LRRK2 CLASP2 SLC10A7 ATP8B2 GGA3 COG6 GCC2 TJAP1 GOLGB1 DOP1A	1.04e-03	443	170	11	GO:0098791
GeneOntologyCellularComponent	cell-substrate junction	FLII PPFIBP1 PAK4 LAMA3 CLASP2 SRCIN1 PRUNE1 FAT1 DST HMCN1 SYNE2	1.04e-03	443	170	11	GO:0030055
Domain	Spectrin	SYNE1 CCDC141 SPTBN4 DST SYNE2	1.89e-06	23	173	5	PF00435
Domain	-	ANKRD31 ACAP1 LRRK2 ANKRD20A2P ANKRD20A3P IBTK ANKRD20A4P ANKEF1 NFKBIA OSBPL1A HECTD1 ANKRD20A1	3.54e-06	248	173	12	1.25.40.20
Domain	Ankyrin_rpt-contain_dom	ANKRD31 ACAP1 LRRK2 ANKRD20A2P ANKRD20A3P IBTK ANKRD20A4P ANKEF1 NFKBIA OSBPL1A HECTD1 ANKRD20A1	4.53e-06	254	173	12	IPR020683
Domain	Ank_2	ANKRD31 ACAP1 ANKRD20A2P ANKRD20A3P IBTK ANKRD20A4P ANKEF1 NFKBIA OSBPL1A HECTD1 ANKRD20A1	5.37e-06	215	173	11	PF12796
Domain	Ankyrin_rpt	ANKRD31 ACAP1 LRRK2 ANKRD20A2P ANKRD20A3P IBTK ANKRD20A4P ANKEF1 NFKBIA OSBPL1A HECTD1 ANKRD20A1	6.22e-06	262	173	12	IPR002110
Domain	Spectrin_repeat	SYNE1 CCDC141 SPTBN4 DST SYNE2	6.38e-06	29	173	5	IPR002017
Domain	Ank	ANKRD31 ACAP1 ANKRD20A2P ANKRD20A3P IBTK ANKRD20A4P ANKEF1 NFKBIA OSBPL1A HECTD1 ANKRD20A1	9.38e-06	228	173	11	PF00023
Domain	PH_DOMAIN	ACAP1 ARHGEF28 ABR PSD VEPH1 OBSCN DGKH SPTBN4 PLEKHG1 OSBPL1A FGD3 PHLPP2	1.17e-05	279	173	12	PS50003
Domain	LRR	FLII LRRIQ3 CNTRL LRRK2 LRRC40 ZYG11B TLR7 LRRTM1 PHLPP2 DRC3	1.85e-05	201	173	10	PS51450
Domain	ANK	ANKRD31 ACAP1 ANKRD20A2P ANKRD20A3P IBTK ANKRD20A4P ANKEF1 NFKBIA OSBPL1A HECTD1 ANKRD20A1	2.30e-05	251	173	11	SM00248
Domain	ANK_REPEAT	ANKRD31 ACAP1 ANKRD20A2P ANKRD20A3P IBTK ANKRD20A4P ANKEF1 NFKBIA OSBPL1A HECTD1 ANKRD20A1	2.48e-05	253	173	11	PS50088
Domain	ANK_REP_REGION	ANKRD31 ACAP1 ANKRD20A2P ANKRD20A3P IBTK ANKRD20A4P ANKEF1 NFKBIA OSBPL1A HECTD1 ANKRD20A1	2.57e-05	254	173	11	PS50297
Domain	RhoGEF	ARHGEF28 ABR OBSCN PLEKHG1 ARHGEF10 FGD3	3.94e-05	68	173	6	SM00325
Domain	PH_dom-like	ACAP1 ARHGEF28 ABR PSD VEPH1 OBSCN DGKH SPTBN4 PLEKHG1 MTMR6 ARHGEF10 OSBPL1A FGD3 PHLPP2	4.45e-05	426	173	14	IPR011993
Domain	RhoGEF	ARHGEF28 ABR OBSCN PLEKHG1 ARHGEF10 FGD3	4.65e-05	70	173	6	PF00621
Domain	DH_2	ARHGEF28 ABR OBSCN PLEKHG1 ARHGEF10 FGD3	4.65e-05	70	173	6	PS50010
Domain	-	ARHGEF28 ABR OBSCN PLEKHG1 ARHGEF10 FGD3	5.04e-05	71	173	6	1.20.900.10
Domain	DH-domain	ARHGEF28 ABR OBSCN PLEKHG1 ARHGEF10 FGD3	5.04e-05	71	173	6	IPR000219
Domain	ACTININ_2	SYNE1 SPTBN4 DST SYNE2	5.49e-05	23	173	4	PS00020
Domain	ACTININ_1	SYNE1 SPTBN4 DST SYNE2	5.49e-05	23	173	4	PS00019
Domain	Actinin_actin-bd_CS	SYNE1 SPTBN4 DST SYNE2	5.49e-05	23	173	4	IPR001589
Domain	PH	ACAP1 ARHGEF28 ABR PSD VEPH1 OBSCN DGKH SPTBN4 PLEKHG1 OSBPL1A FGD3	5.84e-05	278	173	11	SM00233
Domain	PH_domain	ACAP1 ARHGEF28 ABR PSD VEPH1 OBSCN DGKH SPTBN4 PLEKHG1 OSBPL1A FGD3	6.23e-05	280	173	11	IPR001849
Domain	-	ACAP1 ARHGEF28 ABR PSD VEPH1 OBSCN DGKH SPTBN4 PLEKHG1 MTMR6 OSBPL1A FGD3 PHLPP2	7.46e-05	391	173	13	2.30.29.30
Domain	ARM-type_fold	RALGAPA1 PDS5B VEPH1 LRRK2 CLASP2 ZYG11B FMNL3 KPNA7 XPO6 HECTD1 GCN1 NIPBL	7.85e-05	339	173	12	IPR016024
Domain	DHHA2	PRUNE2 PRUNE1	8.53e-05	2	173	2	IPR004097
Domain	DHHA2	PRUNE2 PRUNE1	8.53e-05	2	173	2	PF02833
Domain	DHHA2	PRUNE2 PRUNE1	8.53e-05	2	173	2	SM01131
Domain	Leu-rich_rpt_4	FLII LRRIQ3 LRRK2	8.94e-05	10	173	3	IPR025875
Domain	LRR_4	FLII LRRIQ3 LRRK2	8.94e-05	10	173	3	PF12799
Domain	-	FLII LRRIQ3 CNTRL LRRK2 LRRC40 ZYG11B TLR7 LRRTM1 FBXL21P PHLPP2 DRC3	2.07e-04	321	173	11	3.80.10.10
Domain	SPEC	SYNE1 SPTBN4 DST SYNE2	2.09e-04	32	173	4	SM00150
Domain	Spectrin/alpha-actinin	SYNE1 SPTBN4 DST SYNE2	2.09e-04	32	173	4	IPR018159
Domain	Leu-rich_rpt	FLII LRRIQ3 CNTRL LRRK2 LRRC40 ZYG11B TLR7 LRRTM1 PHLPP2 DRC3	2.24e-04	271	173	10	IPR001611
Domain	-	PDS5B LRRK2 CLASP2 ZYG11B KPNA7 XPO6 HECTD1 GCN1 NIPBL	2.31e-04	222	173	9	1.25.10.10
Domain	L_dom-like	FLII LRRIQ3 CNTRL LRRK2 LRRC40 ZYG11B TLR7 LRRTM1 FBXL21P PHLPP2 DRC3	2.50e-04	328	173	11	IPR032675
Domain	PH	ACAP1 ABR PSD VEPH1 OBSCN DGKH SPTBN4 PLEKHG1 FGD3	2.91e-04	229	173	9	PF00169
Domain	DH_1	ARHGEF28 ABR OBSCN PLEKHG1 ARHGEF10	2.93e-04	63	173	5	PS00741
Domain	CH	IQGAP2 SYNE1 SPTBN4 DST SYNE2	3.39e-04	65	173	5	SM00033
Domain	GDS_CDC24_CS	ABR OBSCN PLEKHG1 ARHGEF10	4.54e-04	39	173	4	IPR001331
Domain	CH	IQGAP2 SYNE1 SPTBN4 DST SYNE2	4.79e-04	70	173	5	PF00307
Domain	KASH	SYNE1 SYNE2	5.06e-04	4	173	2	IPR012315
Domain	G2F	HMCN2 HMCN1	5.06e-04	4	173	2	PF07474
Domain	KASH	SYNE1 SYNE2	5.06e-04	4	173	2	PS51049
Domain	Mib_Herc2	HERC2 HECTD1	5.06e-04	4	173	2	IPR010606
Domain	MIB_HERC2	HERC2 HECTD1	5.06e-04	4	173	2	PS51416
Domain	MIB_HERC2	HERC2 HECTD1	5.06e-04	4	173	2	PF06701
Domain	KASH	SYNE1 SYNE2	5.06e-04	4	173	2	SM01249
Domain	NIDOGEN_G2	HMCN2 HMCN1	5.06e-04	4	173	2	PS50993
Domain	KASH	SYNE1 SYNE2	5.06e-04	4	173	2	PF10541
Domain	GFP	HMCN2 HMCN1	5.06e-04	4	173	2	IPR009017
Domain	G2_nidogen/fibulin_G2F	HMCN2 HMCN1	5.06e-04	4	173	2	IPR006605
Domain	-	IQGAP2 SYNE1 SPTBN4 DST SYNE2	5.11e-04	71	173	5	1.10.418.10
Domain	CH	IQGAP2 SYNE1 SPTBN4 DST SYNE2	5.81e-04	73	173	5	PS50021
Domain	CH-domain	IQGAP2 SYNE1 SPTBN4 DST SYNE2	6.58e-04	75	173	5	IPR001715
Domain	ARM-like	PDS5B LRRK2 CLASP2 ZYG11B KPNA7 XPO6 HECTD1 GCN1 NIPBL	9.52e-04	270	173	9	IPR011989
Domain	LRR_1	FLII CNTRL LRRK2 LRRC40 TLR7 LRRTM1 PHLPP2 DRC3	1.02e-03	219	173	8	PF00560
Domain	-	NBN BRCA1 POLL	1.21e-03	23	173	3	3.40.50.10190
Domain	Alpha_kinase	TRPM7 ALPK1	1.25e-03	6	173	2	PF02816
Domain	MHCK_EF2_kinase	TRPM7 ALPK1	1.25e-03	6	173	2	IPR004166
Domain	TNF_rcpt--assoc_TRAF	TRAF1 TRAF5	1.25e-03	6	173	2	IPR012227
Domain	ALPHA_KINASE	TRPM7 ALPK1	1.25e-03	6	173	2	PS51158
Domain	Alpha_kinase	TRPM7 ALPK1	1.25e-03	6	173	2	SM00811
Domain	LRR_TYP	FLII CNTRL LRRK2 LRRC40 TLR7 LRRTM1 PHLPP2	1.33e-03	177	173	7	SM00369
Domain	Leu-rich_rpt_typical-subtyp	FLII CNTRL LRRK2 LRRC40 TLR7 LRRTM1 PHLPP2	1.33e-03	177	173	7	IPR003591
Domain	BRCT	NBN BRCA1 POLL	1.74e-03	26	173	3	PS50172
Domain	BRCT_dom	NBN BRCA1 POLL	2.16e-03	28	173	3	IPR001357
Domain	FHA	NBN STARD9 CEP170B	2.16e-03	28	173	3	SM00240
Domain	FHA	NBN STARD9 CEP170B	2.90e-03	31	173	3	PF00498
Domain	PH_dom-spectrin-type	PSD SPTBN4	2.94e-03	9	173	2	IPR001605
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RALGAPA1 TET2 CDK16 CDK17 ZNF326 ARHGEF28 TRPM7 PPFIBP1 PAK4 CLASP2 ITPRID2 ALPK1 HDAC7 STIM1 FSIP2 PLEKHG1 DST ARHGEF10 STARD9 SYNE2 AKAP11 CEP152 HECTD1 CEP170B GOLGB1 DOP1A	4.57e-13	861	179	26	36931259
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	RALGAPA1 NRBP1 CDK17 FAM184A MIA3 TRPM7 PPFIBP1 PEG10 SYNE1 PAK4 NUCB2 NBN LRRC40 CLASP2 ITPRID2 RB1CC1 TTC3 STIM1 PLEKHG1 ARHGEF10 MRPS2 SYNE2 VPS13A COPS4 EMC10 AKAP11 HERC2 SEC63 GOLGB1 PCNT NIN	3.13e-11	1487	179	31	33957083
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	PRUNE2 VPS39 PPFIBP1 SYNE1 ALPK1 DST ARHGEF10 XPO6 SYNE2 AKAP11 GCN1 PCNT NIN	1.90e-10	225	179	13	12168954
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	FAM184A ZNF326 MIA3 PPFIBP1 SDCCAG8 CNTRL NBN FCHO2 SPAG5 GGA3 PLEKHG1 IBTK MTMR6 NDC80 CEP135 CEP152 HERC2 CPLANE1 EXOSC7 CEP170B PCNT NIN	6.44e-10	853	179	22	28718761
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RALGAPA1 PRUNE2 MIA3 ABR SDCCAG8 NUCB2 OBSCN LAMA3 DGKH CLASP2 SRCIN1 ZSWIM1 TEP1 TTC3 SLC10A7 TASOR2 SPTBN4 ARHGAP6 ZNF33A GCC2 SLX4IP TJAP1 ZFHX3 HECTD1 CEP170B GOLGB1 DOP1A PCNT	3.12e-09	1489	179	28	28611215
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ZNF326 IQGAP2 TRPM7 PPFIBP1 CNTRL LRRK2 CLASP2 TASOR2 STIM1 FAT1 DST BRCA1 GCC2 NFKBIA VPS13A TJAP1 TXNDC9 ZFHX3 GCN1 GOLGB1	4.22e-09	777	179	20	35844135
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RALGAPA1 CDK16 CDK17 MIA3 PPFIBP1 PAK4 CLASP2 HDAC7 PLEKHG1 PALS1 DST CEP152 HECTD1 CEP170B NIN	1.26e-08	446	179	15	24255178
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	MIA3 PPFIBP1 CLASP2 SPAG5 PRUNE1 IBTK DST AKAP11 CEP152 HECTD1 CEP170B	1.30e-08	209	179	11	36779422
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FLII MAN2A2 ABR VPS39 OBSCN MED14 POMGNT1 GEMIN5 CLASP2 TEP1 TTC3 HDAC7 GGA3 PLEKHG1 FAT1 DST XPO6 POLL HERC2 HECTD1 GCN1 CEP170B PCNT	1.46e-08	1105	179	23	35748872
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	RALGAPA1 FLII WASHC4 VPS39 RADX PPFIBP1 CNTRL ZYG11B STIM1 IBTK MRPS2 GCC2 CEP135 HERC2 HECTD1 GCN1 GOLGB1 PCNT NIN	1.48e-08	754	179	19	33060197
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CLASP2 ITPRID2 RB1CC1 COG6 XPO6 GCC2 SYNE2 GCN1	1.74e-08	87	179	8	12465718
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TPR FLII MIA3 ABR IQGAP2 SYNE1 CLASP2 LRRTM1 JAKMIP3 TTC3 SPTBN4 PALS1 DST KIF15 SYNE2 TJAP1 HERC2 NIPBL CEP170B GOLGB1 PCNT	2.98e-08	963	179	21	28671696
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	4.67e-08	8	179	4	12634303
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	TPR FLII MIA3 PPFIBP1 PEG10 RB1CC1 DST COG6 EEA1 NIPBL MAP4K2 GOLGB1 PCNT	5.37e-08	360	179	13	33111431
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	RALGAPA1 WASHC4 TRPM7 PPFIBP1 POMGNT1 DHX57 STIM1 DST COG6 SYNE2 OSBPL1A VPS13A AKAP11 SEC63 GOLGB1	6.28e-08	504	179	15	34432599
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	FLII MIA3 PPFIBP1 GGA3 PLEKHG1 NDC80 SYNE2 AKAP11 CEP152 CEP170B NIN	8.47e-08	251	179	11	29778605
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CDK16 CDK17 IQGAP2 RADX PPFIBP1 SDCCAG8 PAK4 QTRT2 CLASP2 ZYG11B HDAC7 SPAG5 STIM1 XPO6 GCC2 OSBPL1A COPS4 SLC35F6 AGMAT POLL EEA1 EXOSC7 GCN1 PMFBP1	8.89e-08	1321	179	24	27173435
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RALGAPA1 TET2 WASHC4 VPS39 PAK4 SRCIN1 GGA3 FMNL3 IBTK DST ABCA5 ZBTB5 AKAP11 EXOSC7 NIN	1.17e-07	529	179	15	14621295
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RALGAPA1 MIA3 CTNNAL1 PAK4 NBN CLASP2 ZYG11B ITPRID2 FCHO2 RB1CC1 STIM1 MTMR6 KIF15 SYNE2 CEP135 VPS13A HERC2 GCN1 PHLPP2 PCNT NIN	1.25e-07	1049	179	21	27880917
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TET2 NRBP1 FLII WASHC4 TRPM7 VPS39 PPFIBP1 PEG10 SYNE1 ZNF423 ZNF521 JAKMIP3 TTC3 SPTBN4 DST ARHGEF10 OSBPL1A COPS4 ZBTB5 HERC2 HECTD1 NIPBL PCNT	2.20e-07	1285	179	23	35914814
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TET2 TPR TRIML2 GEMIN5 RB1CC1 SPAG5 DST KIF15 GCC2 ZFHX3 GCN1 GOLGB1 PCNT	2.98e-07	418	179	13	34709266
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	TPR MIA3 VPS39 CNTRL STIM1 CEP135 HECTD1 GCN1 GOLGB1 PCNT NIN	3.03e-07	285	179	11	32838362
Pubmed	A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.	WASHC4 VPS39 CNTRL ZYG11B MRPS2 GCC2 CEP135 HECTD1 GOLGB1 PCNT NIN	4.71e-07	298	179	11	32353859
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	KLHL6 TPR MIA3 CTNNAL1 IQGAP2 VPS39 CNTRL PAK4 AKNAD1 OBSCN GEMIN5 CLASP2 FCHO2 TTC3 SPAG5 MTMR6 SEC63 CPLANE1 GOLGB1 PCNT	9.07e-07	1084	179	20	11544199
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	CDK17 FCHO2 RSC1A1 GGA3 IBTK DST BRCA1 KIF15 UBAC1 COPS4 HERC2 HECTD1 PCNT	1.43e-06	481	179	13	28190767
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PDS5B IQGAP2 PCDHGA11 SYNE1 CNTRL NUCB2 FAM114A2 DHX57 TTC3 TASOR2 SPTBN4 CCDC27 DST BRCA1 STARD9 SYNE2 VPS13A DLEC1 EEA1 NIPBL GOLGB1 DOP1A PCNT	1.59e-06	1442	179	23	35575683
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	PDS5B TPR CDK16 CDK17 ZNF326 WASHC4 SYNE1 CLASP2 SPAG5 TASOR2 SERPINA1 NDC80 CEP135 COPS4 CEP152 EEA1 HERC2 GCN1 NIPBL CEP170B	2.38e-06	1155	179	20	20360068
Pubmed	An EB1-binding motif acts as a microtubule tip localization signal.	CLASP2 STIM1 DST	2.65e-06	6	179	3	19632184
Pubmed	DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.	SYNE1 CCDC141 SPTBN4 PCNT	4.62e-06	22	179	4	12812986
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TPR PAK4 GEMIN5 FAM114A2 NBN SPAG5 GGA3 PRUNE1 IBTK SETD2 DST COPS4 TXNDC9 GCN1 NIPBL GOLGB1 PCNT	7.46e-06	934	179	17	33916271
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	FLII ABR RADX GCC2 ZBTB5 HERC2 NIN	8.19e-06	139	179	7	25476789
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PDS5B SYNE1 ZNF423 ZYG11B GGA3 PLEKHG1 STARD9 GCC2 CEP170B ADGRL3 PCNT	9.43e-06	407	179	11	12693553
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	FLII MIA3 TRPM7 SYNE1 DHX57 LRRC40 DGKH ITPRID2 TTC3 STIM1 IBTK DST NDC80 MRPS2 SYNE2 VPS13A TXNDC9 AKAP11 HERC2 SEC63 GOLGB1 PCNT	9.88e-06	1496	179	22	32877691
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	FAM184A ZNF326 PPFIBP1 SYNE1 MED14 GEMIN5 NBN DHX57 CLASP2 ITPRID2 SETD2 DST BRCA1 MRPS2 SLC35F6 ZFHX3 HERC2 SEC63 EXOSC7 NIPBL CEP170B GOLGB1	9.98e-06	1497	179	22	31527615
Pubmed	An Internally Translated MAVS Variant Exposes Its Amino-terminal TRAF-Binding Motifs to Deregulate Interferon Induction.	TRAF1 TRAF5 NFKBIA	1.10e-05	9	179	3	26221961
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	TRAF5 SDCCAG8 CNTRL CEP135 CEP152 PCNT NIN	1.13e-05	146	179	7	21399614
Pubmed	Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.	CDK16 FAM184A ZNF423 OBSCN NBN BRCA1 NIPBL	1.29e-05	149	179	7	25184681
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	CDK16 CTNNAL1 PPFIBP1 FCHO2 STIM1 PALS1 DST ARHGEF10 MID1 SEC63 GOLGB1	1.29e-05	421	179	11	36976175
Pubmed	A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.	SYNE1 DST CEP152 CEP170B GOLGB1	1.48e-05	60	179	5	20682791
Pubmed	A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation.	CNTRL PCNT NIN	1.57e-05	10	179	3	25220058
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	PRUNE2 ARHGEF10 XPO6 GCC2 ZBTB5 HERC2	1.71e-05	104	179	6	9205841
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	ZNF326 ADAMTS2 ZNF423 SDCCAG8 LRRK2 OBSCN TTC3 RSC1A1 HERC2P3 TASOR2 FAT1 ARHGEF10 RAPGEF3 VPS13A EMC10 CEP152 HERC2 NIPBL CEP170B	1.80e-05	1215	179	19	15146197
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	RALGAPA1 TPR CTNNAL1 ABR PPFIBP1 PAK4 LRRC40 FCHO2 PRUNE1 STIM1 DST SEC63 GCN1 GOLGB1	2.00e-05	708	179	14	39231216
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	PDS5B VPS39 PPFIBP1 SYNE1 PAK4 NUCB2 FAM114A2 PALS1 SERPINA1 ARHGEF10 XPO6 CEP152 HERC2 MAP4K2	2.36e-05	719	179	14	35337019
Pubmed	DNA sequence and analysis of human chromosome 9.	PRUNE2 CTNNAL1 ANKRD20A2P ANKRD20A3P ANKRD20A4P UBAC1 VPS13A SHOC1 ANKRD20A1 FGD3	2.42e-05	370	179	10	15164053
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	2.63e-05	2	179	2	11792814
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	2.63e-05	2	179	2	24931616
Pubmed	CEP110 and ninein are located in a specific domain of the centrosome associated with centrosome maturation.	CNTRL NIN	2.63e-05	2	179	2	11956314
Pubmed	Age related gene DST represents an independent prognostic factor for MYCN non-amplified neuroblastoma.	MYCN DST	2.63e-05	2	179	2	34116676
Pubmed	Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding.	NBN BRCA1	2.63e-05	2	179	2	25939603
Pubmed	HIV replication in CD4+ T lymphocytes in the presence and absence of follicular dendritic cells: inhibition of replication mediated by α-1-antitrypsin through altered IκBα ubiquitination.	SERPINA1 NFKBIA	2.63e-05	2	179	2	21263074
Pubmed	Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas.	PRUNE2 OBSCN	2.63e-05	2	179	2	17360660
Pubmed	hNinein is required for targeting spindle-associated protein Astrin to the centrosome during the S and G2 phases.	SPAG5 NIN	2.63e-05	2	179	2	17383637
Pubmed	Functional analyses of Pericentrin and Syne-2 interaction in ciliogenesis.	SYNE2 PCNT	2.63e-05	2	179	2	30054381
Pubmed	Evi3, a common retroviral integration site in murine B-cell lymphoma, encodes an EBFAZ-related Krüppel-like zinc finger protein.	ZNF423 ZNF521	2.63e-05	2	179	2	12393497
Pubmed	Expression microarray analysis reveals alternative splicing of LAMA3 and DST genes in head and neck squamous cell carcinoma.	LAMA3 DST	2.63e-05	2	179	2	24675808
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	2.63e-05	2	179	2	22768332
Pubmed	Mammalian hemicentin 1 is assembled into tracks in the extracellular matrix of multiple tissues.	HMCN2 HMCN1	2.63e-05	2	179	2	32035013
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	2.63e-05	2	179	2	17267447
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	2.63e-05	2	179	2	24718612
Pubmed	Ovarian cancer patient with germline mutations in both BRCA1 and NBN genes.	NBN BRCA1	2.63e-05	2	179	2	18940477
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	2.63e-05	2	179	2	24586179
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	2.63e-05	2	179	2	17761684
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	2.63e-05	2	179	2	31578382
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	RALGAPA1 MIA3 RADX NUCB2 NBN CLASP2 IBTK SETD2 MTMR6 ARHGEF10 MID1 CEP135 SEC63 HECTD1	2.91e-05	733	179	14	34672954
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PDS5B NRBP1 CDK17 IQGAP2 PPFIBP1 PAK4 DHX57 CLASP2 RB1CC1 HDAC7 IBTK XPO6 UBAC1 CEP135 COPS4 AKAP11 HERC2 SEC63 GCN1	3.82e-05	1284	179	19	17353931
Pubmed	ZNF212 promotes genomic integrity through direct interaction with TRAIP.	TPR SPAG5 COG6 GOLGB1	3.92e-05	37	179	4	36594163
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	TPR MIA3 TRPM7 PPFIBP1 FAM114A2 STIM1 DST GCC2 SYNE2 VPS13A SEC63 GCN1	4.21e-05	568	179	12	37774976
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	CCDC168 ITPRID2 STIM1 FSIP2 DST SYNE2	4.41e-05	123	179	6	26912792
Pubmed	CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion.	CEP135 CEP152 PCNT	4.68e-05	14	179	3	32060285
Pubmed	A human MAP kinase interactome.	TPR SYNE1 CNTRL PAK4 LAMA3 ITPRID2 DST HERC2 CPLANE1 GCN1 GOLGB1	4.78e-05	486	179	11	20936779
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	TPR FLII DHX57 HINFP KPNA7 SETD2 BRCA1 HERC2	4.94e-05	250	179	8	33536335
Pubmed	Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.	TRPM7 GEMIN5 STIM1 DST SYNE2 SEC63 GOLGB1	6.32e-05	191	179	7	31177093
Pubmed	Primary Autosomal Recessive Microcephalies and Seckel Syndrome Spectrum Disorders – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	CEP135 CEP152 NIN	7.15e-05	16	179	3	20301772
Pubmed	Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere.	HMCN2 HMCN1	7.88e-05	3	179	2	12388743
Pubmed	Deficient nonhomologous end-joining activity in cell-free extracts from Brca1-null fibroblasts.	NBN BRCA1	7.88e-05	3	179	2	12124328
Pubmed	N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation.	MYCN TRPM7	7.88e-05	3	179	2	25277194
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SYNE1 SYNE2	7.88e-05	3	179	2	16079285
Pubmed	Complete loss of function of the ubiquitin ligase HERC2 causes a severe neurodevelopmental phenotype.	BRCA1 HERC2	7.88e-05	3	179	2	27759030
Pubmed	Circular RNA circHECTD1 facilitates glioma progression by regulating the miR-296-3p/SLC10A7 axis.	SLC10A7 HECTD1	7.88e-05	3	179	2	33561315
Pubmed	Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes.	TRIML2 FAT1	7.88e-05	3	179	2	36179666
Pubmed	Caspase 6 promotes innate immune activation by functional crosstalk between RIPK1-IκBα axis in liver inflammation.	CASP6 NFKBIA	7.88e-05	3	179	2	37828624
Pubmed	A secreted protein promotes cleavage furrow maturation during cytokinesis.	HMCN2 HMCN1	7.88e-05	3	179	2	21215633
Pubmed	Direct transcriptional repression of Zfp423 by Zfp521 mediates a bone morphogenic protein-dependent osteoblast versus adipocyte lineage commitment switch.	ZNF423 ZNF521	7.88e-05	3	179	2	24891617
Pubmed	Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network.	CLASP2 GCC2	7.88e-05	3	179	2	17543864
Pubmed	SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1.	ZNF423 BRCA1	7.88e-05	3	179	2	28968398
Pubmed	ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies.	ZNF423 ZNF521	7.88e-05	3	179	2	26788497
Pubmed	Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.	SYNE1 SYNE2	7.88e-05	3	179	2	10878022
Pubmed	Transcription Factor ZNF326 Upregulates the Expression of ERCC1 and HDAC7 and its Clinicopathologic Significance in Glioma.	ZNF326 HDAC7	7.88e-05	3	179	2	31930344
Pubmed	The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.	SYNE1 SYNE2	7.88e-05	3	179	2	12408964
Pubmed	Characterization and physical mapping in human and mouse of a novel RING finger gene in Xp22.	ARHGAP6 MID1	7.88e-05	3	179	2	9722948
Pubmed	FIP200 Suppresses Immune Checkpoint Therapy Responses in Breast Cancers by Limiting AZI2/TBK1/IRF Signaling Independent of Its Canonical Autophagy Function.	RB1CC1 BRCA1	7.88e-05	3	179	2	32580962
Pubmed	Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.	SYNE1 SYNE2	7.88e-05	3	179	2	17462627
Pubmed	Loss of holocytochrome c-type synthetase causes the male lethality of X-linked dominant microphthalmia with linear skin defects (MLS) syndrome.	ARHGAP6 MID1	7.88e-05	3	179	2	12444108
Pubmed	Hemicentins assemble on diverse epithelia in the mouse.	HMCN2 HMCN1	7.88e-05	3	179	2	17015624
Pubmed	TUSC4 functions as a tumor suppressor by regulating BRCA1 stability.	BRCA1 HERC2	7.88e-05	3	179	2	25480944
Pubmed	Astrin-SKAP complex reconstitution reveals its kinetochore interaction with microtubule-bound Ndc80.	SPAG5 NDC80	7.88e-05	3	179	2	28841134
Pubmed	Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.	SYNE1 SYNE2	7.88e-05	3	179	2	33472039
Pubmed	Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer.	RB1CC1 BRCA1	7.88e-05	3	179	2	29938573
Pubmed	HERC2 is an E3 ligase that targets BRCA1 for degradation.	BRCA1 HERC2	7.88e-05	3	179	2	20631078
Interaction	PCM1 interactions	FAM184A CNTRL ITPRID2 RB1CC1 TTC3 SPAG5 PLEKHG1 IBTK KIF15 NDC80 GCC2 CEP135 CEP152 EEA1 HERC2 CEP170B PCNT NIN	6.14e-08	434	178	18	int:PCM1
Interaction	RPGRIP1L interactions	CNTRL SPAG5 PLEKHG1 IBTK NDC80 CEP135 CEP152 SEC63 CPLANE1 HECTD1 CEP170B PCNT NIN	1.08e-07	225	178	13	int:RPGRIP1L
Interaction	HERC2 interactions	FLII ABR RADX LRRK2 MED14 RB1CC1 TTC3 DST BRCA1 KIF15 NDC80 GCC2 SYNE2 CEP135 ZBTB5 HERC2 HECTD1 ODAD3 NIN	1.12e-07	503	178	19	int:HERC2
Interaction	NDC80 interactions	MIA3 TRPM7 SPAG5 PLEKHG1 KIF15 NDC80 GCC2 SYNE2 OSBPL1A CEP135 CEP152 HERC2 CEP170B PCNT NIN	1.24e-07	312	178	15	int:NDC80
Interaction	YWHAH interactions	RALGAPA1 TET2 CDK16 CDK17 ZNF326 ARHGEF28 TRPM7 PPFIBP1 CNTRL PAK4 LRRK2 CLASP2 ITPRID2 RB1CC1 HDAC7 STIM1 PLEKHG1 DST STARD9 SYNE2 CEP135 AKAP11 CEP152 HECTD1 CEP170B DOP1A PCNT NIN	4.30e-07	1102	178	28	int:YWHAH
Interaction	OFD1 interactions	FAM184A SDCCAG8 CNTRL NBN RB1CC1 SPAG5 PLEKHG1 NDC80 CEP135 CEP152 SEC63 CEP170B DRC3 PCNT NIN	4.84e-07	347	178	15	int:OFD1
Interaction	NIN interactions	FAM184A MIA3 CNTRL CLASP2 SPAG5 PLEKHG1 NDC80 CEP135 CEP152 HERC2 CPLANE1 HECTD1 CEP170B PCNT NIN	7.42e-07	359	178	15	int:NIN
Interaction	CEP170 interactions	MYCN CNTRL RB1CC1 SPAG5 MTMR6 BRCA1 SYNE2 CEP135 TXNDC9 HERC2 HECTD1 ODAD3 CEP170B NIN	9.51e-07	318	178	14	int:CEP170
Interaction	WHAMMP3 interactions	FAM184A SYNE1 CNTRL SPAG5 COG6 GCC2 CEP152 PCNT NIN	1.12e-06	119	178	9	int:WHAMMP3
Interaction	CCDC138 interactions	FAM184A CNTRL RB1CC1 NDC80 UBAC1 CEP135 CEP152 PCNT NIN	1.48e-06	123	178	9	int:CCDC138
Interaction	YWHAQ interactions	RALGAPA1 MYCN TET2 TPR NRBP1 CDK16 CDK17 ARHGEF28 TRPM7 PPFIBP1 PAK4 LRRK2 CLASP2 ITPRID2 HDAC7 SERPINA1 DST BRCA1 STARD9 COPS4 TXNDC9 AKAP11 HECTD1 GCN1 CEP170B GOLGB1 DOP1A	1.87e-06	1118	178	27	int:YWHAQ
Interaction	SYCE1 interactions	TRAF1 MIA3 CNTRL SPAG5 NDC80 MID1 TJAP1 CEP152 EEA1	1.94e-06	127	178	9	int:SYCE1
Interaction	MED4 interactions	FLII FAM184A CNTRL MED14 GEMIN5 NBN SPAG5 DST NDC80 CEP135 TXNDC9 CEP152 HERC2 HECTD1 PCNT NIN	2.59e-06	450	178	16	int:MED4
Interaction	FAM184A interactions	FAM184A LRRK2 LRRC40 PLEKHG1 BRCA1 PCNT NIN	3.38e-06	72	178	7	int:FAM184A
Interaction	AMOT interactions	MIA3 SPAG5 PLEKHG1 PALS1 KIF15 NDC80 MRPS2 NFKBIA SEPTIN1 CEP152 HECTD1 PCNT NIN	4.30e-06	312	178	13	int:AMOT
Interaction	YWHAZ interactions	RALGAPA1 MYCN TET2 CDK16 CDK17 ARHGEF28 TRPM7 PPFIBP1 PAK4 LRRK2 CLASP2 ITPRID2 RB1CC1 HDAC7 SPAG5 STIM1 FSIP2 DST BRCA1 KIF15 STARD9 GCC2 SYNE2 AKAP11 HERC2 HECTD1 CEP170B PCNT NIN	4.76e-06	1319	178	29	int:YWHAZ
Interaction	HDAC1 interactions	MYCN TET2 TPR FLII TRPM7 ZNF423 ZNF521 GEMIN5 RB1CC1 HDAC7 SPAG5 DST BRCA1 KIF15 GCC2 NFKBIA SYNE2 CEP135 ZBTB5 PLAGL1 ZFHX3 HECTD1 EXOSC7 GCN1 GOLGB1 PCNT	5.00e-06	1108	178	26	int:HDAC1
Interaction	SEPTIN10 interactions	SPAG5 BRCA1 KIF15 GCC2 SEPTIN1 CEP152 GOLGB1 PCNT NIN	5.47e-06	144	178	9	int:SEPTIN10
Interaction	CEP135 interactions	MIA3 TRPM7 PLEKHG1 IBTK NDC80 CEP135 CEP152 HERC2 CEP170B GOLGB1 PCNT NIN	5.70e-06	272	178	12	int:CEP135
Interaction	KRT19 interactions	TRPM7 RB1CC1 SPAG5 PLEKHG1 KIF15 NDC80 GCC2 COPS4 POLL CEP152 PCNT NIN	8.21e-06	282	178	12	int:KRT19
Interaction	CEP85L interactions	CNTRL NDC80 CEP135 PCNT NIN	9.87e-06	33	178	5	int:CEP85L
Interaction	PFN1 interactions	TPR FLII NBN FCHO2 SPAG5 GGA3 BRCA1 KIF15 XPO6 GCC2 SYNE2 CEP152 HECTD1 ODAD3 GOLGB1 PCNT	1.22e-05	509	178	16	int:PFN1
Interaction	DYNLL1 interactions	MYCN TPR RASGRP4 PPFIBP1 NBN ANKRD20A2P RB1CC1 SPAG5 PRUNE1 ANKRD20A4P MRPS2 NFKBIA COPS4 CEP152 GOLGB1 PCNT	1.25e-05	510	178	16	int:DYNLL1
Interaction	MIB1 interactions	FAM184A PEG10 CNTRL GEMIN5 FCHO2 RB1CC1 IBTK NDC80 CEP135 GCN1 PCNT NIN	1.29e-05	295	178	12	int:MIB1
Interaction	ANKRD20A4P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	1.33e-05	6	178	3	int:ANKRD20A4P
Interaction	SYCE3 interactions	CNTRL RB1CC1 SPAG5 COG6 COPS4 NIN	1.95e-05	63	178	6	int:SYCE3
Interaction	BORCS6 interactions	FAM184A VPS39 DGKH SPAG5 NDC80 CEP135 GOLGB1 PCNT NIN	2.08e-05	170	178	9	int:BORCS6
Interaction	ANKRD20A2P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	2.31e-05	7	178	3	int:ANKRD20A2P
Interaction	DYNLL2 interactions	MYCN PPFIBP1 ANKRD20A2P TTC3 SPAG5 ANKRD20A4P CEP152 CEP170B ANKRD20A1 GOLGB1 PCNT	2.31e-05	263	178	11	int:DYNLL2
Interaction	CEP290 interactions	PEG10 ZNF423 TTC3 DST NDC80 CEP135 HERC2 PCNT NIN	3.13e-05	179	178	9	int:CEP290
Interaction	YWHAB interactions	RALGAPA1 MYCN TET2 NRBP1 CDK16 CDK17 ARHGEF28 TRPM7 PPFIBP1 PAK4 LRRK2 CLASP2 ITPRID2 RB1CC1 HDAC7 STIM1 DST STARD9 GCC2 PRMT9 AKAP11 HECTD1 CEP170B	3.16e-05	1014	178	23	int:YWHAB
Interaction	YWHAG interactions	RALGAPA1 MYCN TET2 NRBP1 CDK16 CDK17 ARHGEF28 TRPM7 PPFIBP1 PAK4 LRRK2 CLASP2 ITPRID2 RB1CC1 HDAC7 STIM1 PLEKHG1 DST KIF15 STARD9 GCC2 SYNE2 AKAP11 HECTD1 CEP170B DOP1A	3.94e-05	1248	178	26	int:YWHAG
Interaction	SYNE3 interactions	MIA3 TRPM7 NUCB2 ITPRID2 SPAG5 STIM1 PLEKHG1 DST SYNE2 CEP152 SEC63 CEP170B PCNT NIN	4.22e-05	444	178	14	int:SYNE3
Interaction	TRIM36 interactions	PAK4 CLASP2 SPAG5 BRCA1 KIF15 NDC80 CEP135 CEP170B	4.29e-05	144	178	8	int:TRIM36
Interaction	SFN interactions	RALGAPA1 TET2 NRBP1 ARHGEF28 TRPM7 PPFIBP1 PAK4 LRRK2 CLASP2 ITPRID2 HDAC7 DST ARHGEF10 AKAP11 EEA1 HECTD1 CEP170B DOP1A	4.34e-05	692	178	18	int:SFN
Interaction	RAB35 interactions	RALGAPA1 CDK16 IQGAP2 TRPM7 PPFIBP1 CNTRL PAK4 FCHO2 STIM1 PALS1 DST ARHGEF10 SYNE2 VPS13A SEC63 GOLGB1	5.13e-05	573	178	16	int:RAB35
Interaction	PCNT interactions	FAM184A SYNE1 CNTRL DST NDC80 CEP135 CEP152 NIPBL PCNT NIN	5.85e-05	241	178	10	int:PCNT
Interaction	TBK1 interactions	TPR TRAF1 TRAF5 CNTRL RB1CC1 DST NDC80 NFKBIA CEP135 CEP152 HERC2 SEC63 NIN	6.18e-05	402	178	13	int:TBK1
Interaction	GJA1 interactions	MIA3 CTNNAL1 TRPM7 PPFIBP1 PAK4 FCHO2 GGA3 STIM1 DST ARHGEF10 GCC2 SYNE2 TMPRSS3 VPS13A TJAP1 GOLGB1	6.29e-05	583	178	16	int:GJA1
Interaction	CCDC22 interactions	SPAG5 NDC80 COG6 CEP135 HERC2 ODAD3 DRC3 NIN	6.29e-05	152	178	8	int:CCDC22
Interaction	CEP128 interactions	CTNNAL1 WASHC4 CNTRL PLEKHG1 PALS1 IBTK NDC80 CEP135 CEP152 CEP170B NIN	6.97e-05	297	178	11	int:CEP128
Interaction	VPS33B interactions	MIA3 PPFIBP1 ITPRID2 PLEKHG1 SYNE2 AKAP11 CEP152 CEP170B NIN	7.13e-05	199	178	9	int:VPS33B
Interaction	PIBF1 interactions	FAM184A TRAF5 CNTRL NDC80 CEP135 ZFHX3 EEA1 PCNT NIN	7.41e-05	200	178	9	int:PIBF1
Interaction	NEURL4 interactions	LRRK2 RB1CC1 SPAG5 CEP135 HERC2 HECTD1 ODAD3	7.73e-05	116	178	7	int:NEURL4
Interaction	RAB9A interactions	RALGAPA1 MIA3 WASHC4 TRPM7 PPFIBP1 CNTRL PAK4 STIM1 MTMR6 DST GCC2 SYNE2 VPS13A EEA1 SEC63 GOLGB1	7.98e-05	595	178	16	int:RAB9A
Interaction	ODF2 interactions	TRAF5 CNTRL PLEKHG1 IBTK BRCA1 NDC80 CEP135 NIN	8.26e-05	158	178	8	int:ODF2
Interaction	TMT1A interactions	MIA3 TRPM7 SYNE1 FAM114A2 CCDC168 STIM1 GCC2 SYNE2 VPS13A TJAP1 SEC63 GOLGB1	8.71e-05	359	178	12	int:TMT1A
Interaction	TOP3B interactions	MYCN FLII MAN2A2 ABR VPS39 VEPH1 OBSCN MED14 POMGNT1 GEMIN5 DHX57 CLASP2 TEP1 TTC3 HDAC7 GGA3 PLEKHG1 IBTK FAT1 DST NDC80 XPO6 POLL HERC2 HECTD1 GCN1 CEP170B PCNT	9.28e-05	1470	178	28	int:TOP3B
Interaction	CEP170B interactions	RALGAPA1 CNTRL NDC80 CEP135 CEP170B NIN	9.38e-05	83	178	6	int:CEP170B
Interaction	DTNBP1 interactions	IQGAP2 TRIML2 SYNE1 AKNAD1 SPAG5 DST COG6 PCNT	9.84e-05	162	178	8	int:DTNBP1
Interaction	ACBD5 interactions	PEG10 DGKH SPAG5 GGA3 STIM1 NDC80 SYNE2 SEC63 PCNT	1.04e-04	209	178	9	int:ACBD5
Interaction	ANKRD20A1 interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	1.06e-04	11	178	3	int:ANKRD20A1
Interaction	BRK1 interactions	MIA3 SRCIN1 RB1CC1 COG6 GCC2 EEA1 PCNT	1.18e-04	124	178	7	int:BRK1
Interaction	THOC6 interactions	MYCN TPR ZNF326 BRCA1 HERC2 HECTD1	1.22e-04	87	178	6	int:THOC6
Interaction	CKAP2 interactions	MYCN CNTRL TTC3 STIM1 HERC2 HECTD1 NIN	1.30e-04	126	178	7	int:CKAP2
Interaction	TBC1D31 interactions	FAM184A CNTRL NDC80 CEP135 NIN	1.35e-04	56	178	5	int:TBC1D31
Interaction	DCTN1 interactions	TPR FLII PAK4 MED14 DHX57 CLASP2 SPAG5 IBTK DST BRCA1 NDC80 HECTD1 CEP170B NIN	1.40e-04	497	178	14	int:DCTN1
Interaction	CCDC14 interactions	CNTRL SPAG5 NDC80 CEP135 CEP152 PCNT NIN	1.51e-04	129	178	7	int:CCDC14
Interaction	LMAN1 interactions	RALGAPA1 MIA3 TRPM7 PPFIBP1 PAK4 RB1CC1 STIM1 SERPINA1 DST SYNE2 VPS13A SEC63 GOLGB1	1.56e-04	441	178	13	int:LMAN1
Interaction	TCHP interactions	FAM184A CNTRL NDC80 CEP135 CEP152 PCNT NIN	1.66e-04	131	178	7	int:TCHP
Interaction	MAP6 interactions	TRAF1 PEG10 SLX4IP HERC2	1.74e-04	32	178	4	int:MAP6
Interaction	STX6 interactions	RALGAPA1 MIA3 PPFIBP1 PAK4 GGA3 STIM1 MTMR6 DST COG6 ARHGEF10 GCC2 EEA1 GOLGB1	1.82e-04	448	178	13	int:STX6
Interaction	ODAD1 interactions	SDCCAG8 SPAG5 COG6 ODAD3 PCNT	1.87e-04	60	178	5	int:ODAD1
Interaction	CEP63 interactions	RALGAPA1 SYNE1 DST NDC80 CEP135 CEP152 PCNT NIN	1.96e-04	179	178	8	int:CEP63
Interaction	GJD3 interactions	MIA3 TRPM7 PPFIBP1 SYNE1 PAK4 FAM114A2 GGA3 STIM1 DST GCC2 SYNE2 SEC63 GOLGB1	2.07e-04	454	178	13	int:GJD3
Interaction	CSPP1 interactions	FAM184A CNTRL NDC80 CEP135 PCNT NIN	2.10e-04	96	178	6	int:CSPP1
Interaction	MAPRE3 interactions	CLASP2 SPAG5 STIM1 IBTK DST KIF15 NDC80 CEP170B PCNT	2.13e-04	230	178	9	int:MAPRE3
Interaction	CPAP interactions	GEMIN5 CLASP2 IBTK NDC80 CEP135 CEP152 PCNT NIN	2.19e-04	182	178	8	int:CPAP
Interaction	ARF6 interactions	CDK16 ACAP1 IQGAP2 TRPM7 PPFIBP1 CNTRL PAK4 FCHO2 ATP8B2 GGA3 STIM1 PALS1 TJAP1 ZFHX3 SEC63	2.20e-04	584	178	15	int:ARF6
Interaction	C2CD3 interactions	CNTRL NDC80 CEP135 NIN	2.22e-04	34	178	4	int:C2CD3
Interaction	GOLGA1 interactions	PLEKHG1 DST GCC2 TJAP1 CEP152 CEP170B GOLGB1 PCNT	2.28e-04	183	178	8	int:GOLGA1
Interaction	CLASP1 interactions	TPR CNTRL CLASP2 SPAG5 GCC2 HECTD1 NIN	2.28e-04	138	178	7	int:CLASP1
Interaction	TXLNG interactions	CNTRL NDC80 CEP135 HERC2 HECTD1 NIN	2.35e-04	98	178	6	int:TXLNG
Interaction	H1-5 interactions	MYCN CTNNAL1 MAN2A2 IQGAP2 SYNE1 CNTRL DHX57 CCDC168 TASOR2 SYT16 WDR87 SEPTIN1 SLX4IP	2.50e-04	463	178	13	int:H1-5
Interaction	SSX2IP interactions	FAM184A CNTRL PLEKHG1 BRCA1 NDC80 CEP135 POLL HERC2 PCNT NIN	2.51e-04	288	178	10	int:SSX2IP
Interaction	KDM1A interactions	MYCN TET2 TPR FLII TRIML2 GEMIN5 RB1CC1 SPAG5 DST BRCA1 KIF15 GCC2 ANKEF1 ZFHX3 CEP152 GCN1 ODAD3 GOLGB1 PCNT NIN	2.54e-04	941	178	20	int:KDM1A
Interaction	STX7 interactions	RALGAPA1 MIA3 CTNNAL1 TRPM7 PPFIBP1 PAK4 FCHO2 GGA3 STIM1 MTMR6 DST ARHGEF10 SYNE2 EEA1 SEC63 GOLGB1	2.56e-04	659	178	16	int:STX7
Interaction	TXLNA interactions	CNTRL DST BRCA1 NDC80 OSBPL1A CEP135 CEP152 HECTD1 NIN	2.58e-04	236	178	9	int:TXLNA
Interaction	DMD interactions	CTNNAL1 SYNE1 FCHO2 KIF15 SYNE2 OSBPL1A GOLGB1	2.61e-04	141	178	7	int:DMD
Interaction	ERC1 interactions	CNTRL BRCA1 NDC80 NFKBIA CEP135 CEP152 EEA1 NIN	2.64e-04	187	178	8	int:ERC1
Interaction	KCNA3 interactions	RALGAPA1 TPR CTNNAL1 ABR PPFIBP1 PAK4 LRRK2 AKNAD1 LRRC40 FCHO2 PRUNE1 STIM1 DST MID1 VPS13A SEC63 GCN1 GOLGB1 DOP1A	2.64e-04	871	178	19	int:KCNA3
Interaction	PEX14 interactions	IQGAP2 SPAG5 PLEKHG1 KIF15 GCC2 SYNE2 COPS4 CEP170B PCNT	2.66e-04	237	178	9	int:PEX14
Interaction	YWHAE interactions	RALGAPA1 MYCN TET2 CDK16 CDK17 ARHGEF28 TRPM7 PPFIBP1 PAK4 LRRK2 CLASP2 SRCIN1 ITPRID2 RB1CC1 TTC3 HDAC7 STIM1 DST BRCA1 GCC2 AKAP11 HECTD1 CEP170B NIN	2.95e-04	1256	178	24	int:YWHAE
Interaction	GORASP1 interactions	CLASP2 STIM1 KIF15 GCC2 SLX4IP GOLGB1	3.07e-04	103	178	6	int:GORASP1
Interaction	TEX9 interactions	NDC80 CEP135 TXNDC9 NIN	3.09e-04	37	178	4	int:TEX9
Interaction	CEP192 interactions	FAM184A SDCCAG8 CNTRL NDC80 CEP135 CEP152 PCNT NIN	3.15e-04	192	178	8	int:CEP192
Interaction	SYNC interactions	GEMIN5 KIF15 NDC80 GCC2 TJAP1	3.15e-04	67	178	5	int:SYNC
Interaction	PLEKHG1 interactions	FAM184A PLEKHG1 NDC80 CEP135 NIN	3.15e-04	67	178	5	int:PLEKHG1
Interaction	RAB7A interactions	RALGAPA1 WASHC4 TRPM7 VPS39 PPFIBP1 CNTRL LRRK2 POMGNT1 DHX57 ITPRID2 STIM1 DST COG6 SYNE2 OSBPL1A VPS13A AKAP11 SEC63 GOLGB1	3.27e-04	886	178	19	int:RAB7A
Interaction	DCTN2 interactions	TPR FLII CLASP2 SPAG5 KIF15 ARHGEF10 GCC2 CEP152 HECTD1 PCNT NIN	3.37e-04	356	178	11	int:DCTN2
Interaction	SNW1 interactions	MYCN TPR TRAF1 ZNF326 VPS39 PEG10 PAK4 NBN LRRC40 NDC80 XPO6 HECTD1 EXOSC7 GCN1 NIPBL MAP4K2 NIN	3.47e-04	747	178	17	int:SNW1
Interaction	KRT18 interactions	FLII TRPM7 CASP6 RB1CC1 SPAG5 SERPINA1 BRCA1 KIF15 CEP152 HECTD1 PCNT NIN	3.62e-04	419	178	12	int:KRT18
Interaction	CEP350 interactions	CNTRL BRCA1 NDC80 CEP135 CEP152 PCNT NIN	3.65e-04	149	178	7	int:CEP350
Interaction	EBAG9 interactions	WASHC4 PPFIBP1 PAK4 FAM114A2 GGA3 MTMR6 DST GCC2 TJAP1 GOLGB1	3.76e-04	303	178	10	int:EBAG9
Interaction	LAMP3 interactions	RALGAPA1 CDK16 WASHC4 TRPM7 PPFIBP1 PAK4 FCHO2 STIM1 GCC2 SYNE2 TJAP1 EEA1 GOLGB1	3.97e-04	486	178	13	int:LAMP3
Interaction	CEP131 interactions	FAM184A CNTRL IBTK NDC80 CEP135 CEP152 PCNT NIN	4.14e-04	200	178	8	int:CEP131
Interaction	HMMR interactions	LRRK2 BRCA1 NDC80 HECTD1 MAP4K2 NIN	4.17e-04	109	178	6	int:HMMR
Interaction	BICD2 interactions	TPR LRRK2 FCHO2 IBTK MTMR6 NDC80 COG6 CEP135 HERC2 EXOSC7 CEP170B NIN	4.20e-04	426	178	12	int:BICD2
Interaction	EBF1 interactions	TET2 ZNF423 ZNF521	4.21e-04	17	178	3	int:EBF1
Interaction	GPATCH1 interactions	MYCN CNTRL CEP135 CEP152 HECTD1 NIN	4.59e-04	111	178	6	int:GPATCH1
GeneFamily	Ankyrin repeat domain containing	ANKRD31 ACAP1 ANKRD20A2P ANKRD20A3P IBTK ANKRD20A4P ANKEF1 NFKBIA OSBPL1A HECTD1 ANKRD20A1	5.35e-07	242	118	11	403
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ACAP1 ABR PSD VEPH1 DGKH SPTBN4 PLEKHG1 FGD3 PHLPP2	8.32e-06	206	118	9	682
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ABR OBSCN PLEKHG1 ARHGEF10 FGD3	7.07e-05	66	118	5	722
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	2.51e-04	4	118	2	1252
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	NBN BRCA1	4.17e-04	5	118	2	1336
GeneFamily	TNF receptor associated factors	TRAF1 TRAF5	8.68e-04	7	118	2	1056
GeneFamily	Fibulins	HMCN2 HMCN1	1.15e-03	8	118	2	556
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF326 ZNF423 ZNF521 ZNF772 ZNF524 HINFP ZNF878 ZNF33A ZBTB5 PLAGL1 ZFHX3 ZNF470	2.56e-03	718	118	12	28
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	PDS5B CTNNAL1 IQGAP2 NUCB2 NBN LRRC40 RB1CC1 TASOR2 BRCA1 KIF15 NDC80 ABCA5 COG6 GCC2 SYNE2 MID1 OSBPL1A AKAP11 EEA1 SEC63 CPLANE1 HECTD1 NIPBL GOLGB1 NIN	3.23e-12	656	178	25	M18979
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	PDS5B CDK17 WASHC4 NBN CLASP2 RB1CC1 IBTK SETD2 FAT1 DST BRCA1 NDC80 ARHGEF10 XPO6 GCC2 SYNE2 MID1 CEP135 VPS13A AKAP11 ZFHX3 NIPBL PHLPP2 PCNT	4.39e-09	856	178	24	M4500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	CDK17 WASHC4 NBN CLASP2 IBTK SETD2 FAT1 DST BRCA1 NDC80 MID1 CEP135 VPS13A PHLPP2	3.98e-06	466	178	14	M13522
Coexpression	GSE14769_UNSTIM_VS_20MIN_LPS_BMDM_DN	RALGAPA1 TRAF1 TRAF5 PSD SYT16 BRCA1 NFKBIA DOP1A PHLPP2	9.71e-06	200	178	9	M3491
Coexpression	GSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_DN	FLII LRRK2 ZNF521 ZYG11B ITPRID2 MTMR6 NFKBIA EEA1 HERC2	9.71e-06	200	178	9	M4373
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN	PDS5B RB1CC1 DST ARHGEF10 ZFHX3 PCNT	2.36e-05	84	178	6	M13008
Coexpression	GABRIELY_MIR21_TARGETS	ZNF326 TRPM7 CNTRL ZYG11B PALS1 SYNE2 VPS13A SEC63 HECTD1 NIPBL	3.04e-05	289	178	10	M2196
Coexpression	GSE360_CTRL_VS_L_MAJOR_MAC_DN	ACAP1 TRAF5 ITPRID2 SPAG5 MTMR6 ZBTB5 DLEC1 DRC3	6.33e-05	197	178	8	M5161
Coexpression	HALLMARK_MITOTIC_SPINDLE	ABR CNTRL DST KIF15 NDC80 MID1 PCNT NIN	6.80e-05	199	178	8	M5893
Coexpression	GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_LPS_STIM_UP	CDK17 WASHC4 TTC3 NFKBIA CEP135 EMC10 SEC63 CPLANE1	7.04e-05	200	178	8	M6352
Coexpression	GSE3982_MAST_CELL_VS_TH2_DN	TPR TRAF1 PPFIBP1 SPAG5 MRPS2 TMPRSS3 CEP152 MAP4K2	7.04e-05	200	178	8	M5456
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000	RALGAPA1 TPR TRAF5 IQGAP2 PEG10 MED14 LAMA3 CLASP2 SLC10A7 SPAG5 TASOR2 ARHGAP6 IBTK DST HMCN1 ABCA5 VPS13A PLAGL1 HERC2 CPLANE1 GCN1 ADGRL3	1.05e-06	806	177	22	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000	RALGAPA1 TPR IQGAP2 PEG10 MED14 CLASP2 SLC10A7 SPAG5 IBTK VPS13A PLAGL1 HERC2 CPLANE1 GCN1	2.78e-06	369	177	14	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	TPR FAM184A ZNF326 TRPM7 RADX CNTRL VEPH1 MED14 NBN TLR7 SPAG5 SERPINA1 BRCA1 KIF15 NDC80 XPO6 GCC2 SYNE2 MID1 CEP135 VPS13A ZFHX3 SEC63 CPLANE1 NIPBL	4.69e-05	1257	177	25	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	FAM184A MED14 SPAG5 BRCA1 KIF15 GCC2 SYNE2 CEP135 HECTD1 NIPBL MAP3K19	6.30e-05	311	177	11	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000	PDS5B IQGAP2 TRPM7 PEG10 CLASP2 TTC3 SLC10A7 IBTK HERC2 CPLANE1 ADGRL3	1.07e-04	330	177	11	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_MaxArch_2500_K3	KLHL6 TET2 TPR TRAF1 ZNF326 TRPM7 CNTRL VEPH1 LRRC40 FCHO2 RB1CC1 SERPINA1 ZNF878 KIF15 NDC80 XPO6 GCC2 SYNE2 MID1 CEP135 VPS13A ZFHX3 CPLANE1 NIPBL	1.19e-04	1252	177	24	facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000	PDS5B IQGAP2 TRPM7 PEG10 CLASP2 SLC10A7 PALS1 IBTK PLAGL1 HERC2 CPLANE1 GCN1	1.31e-04	397	177	12	gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#2_top-relative-expression-ranked_1000	KLHL6 PEG10 ZNF521 HMCN1 PLAGL1	1.68e-04	62	177	5	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k2_1000
CoexpressionAtlas	dev gonad_e12.5_F_DevVasOvary_Flk_top-relative-expression-ranked_1000	KLHL6 CDK17 ARHGEF28 PPFIBP1 PEG10 ZNF423 ZNF521 DGKH HDAC7 FMNL3 PLEKHG1 SERPINA1 HMCN1 RAPGEF3 NFKBIA SEPTIN1 PLAGL1 MAP4K2	1.70e-04	817	177	18	gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	DHX57 ZYG11B STIM1 ZNF878 BRCA1 GCC2 SEC63 CPLANE1 NIPBL NIN	1.72e-04	291	177	10	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_1000	KLHL6 PDS5B IQGAP2 ADAMTS2 LRRK2 MED14 ZNF521 ITPRID2 CCDC141 SPAG5 BRCA1 HMCN1 ABCA5 MID1 SEC63 NIPBL MAP4K2 ADGRL3	1.75e-04	819	177	18	gudmap_developingKidney_e15.5_Peripheral blastema_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4	MYCN TPR FAM184A ZNF326 TRPM7 CNTRL PAK4 MED14 ZNF521 CPT1B TTC3 SPAG5 GGA3 FAT1 BRCA1 KIF15 GCC2 SYNE2 CEP135 VPS13A SLC35F6 PRMT9 CPLANE1 NIPBL FGD3	1.83e-04	1370	177	25	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	TPR ZNF326 TRPM7 FCHO2 SPTBN4 GCC2 MID1 CEP135 NIPBL GOLGB1	2.09e-04	298	177	10	Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	RALGAPA1 FLII FAM184A MED14 DHX57 LRRTM1 RB1CC1 SPAG5 SETD2 BRCA1 KIF15 SYNE2 CEP135 VPS13A EEA1 HECTD1 NIPBL MAP3K19	2.10e-04	831	177	18	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	dev gonad_e13.5_F_DevVascOvary_Flk_top-relative-expression-ranked_1000	KLHL6 CDK17 ARHGEF28 PPFIBP1 PEG10 ZNF423 ZNF521 DGKH HDAC7 FMNL3 PLEKHG1 HMCN1 RAPGEF3 STARD9 NFKBIA PLAGL1 MAP4K2 NIN	2.10e-04	831	177	18	gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	MYCN TPR FAM184A ZNF326 IQGAP2 TRPM7 ZNF423 CNTRL VEPH1 CPT1B SPAG5 BRCA1 KIF15 GCC2 SYNE2 MID1 OSBPL1A CEP135 VPS13A NIPBL FGD3	2.10e-04	1060	177	21	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	kidney_adult_Podocyte_MafB_top-relative-expression-ranked_1000	FAM184A CTNNAL1 IQGAP2 SYNE1 DGKH TLR7 ITPRID2 ALPK1 RB1CC1 PLEKHG1 PALS1 MTMR6 FAT1 DST ABCA5 RAPGEF3 VPS13A PLAGL1	2.32e-04	838	177	18	gudmap_kidney_adult_Podocyte_MafB_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	RALGAPA1 FLII DHX57 ZYG11B RB1CC1 SETD2 BRCA1 COG6 GCC2 SYNE2 VPS13A SEPTIN1 EEA1 SEC63 CPLANE1 NIPBL NIN	2.94e-04	780	177	17	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#5_top-relative-expression-ranked_1000	RALGAPA1 TRPM7 MED14 CLASP2 PPP1R3C IBTK VPS13A CPLANE1	3.12e-04	203	177	8	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	NUCB2 LRRTM1 SPAG5 PALS1 DST BRCA1 KIF15 STARD9 SYNE2 CEP135 VPS13A PLAGL1 DOP1A PHLPP2 PCNT	3.97e-04	654	177	15	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000	RALGAPA1 TPR IQGAP2 MED14 CLASP2 IBTK PLAGL1 HERC2 CPLANE1 GCN1 ADGRL3	4.02e-04	385	177	11	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_500	RALGAPA1 WASHC4 SDCCAG8 MED14 IBTK VPS13A CPLANE1	4.44e-04	163	177	7	gudmap_developingKidney_e15.5_cortic collect duct_500_k4
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CTNNAL1 ZNF521 DGKH ITPRID2 HDAC7 DST HMCN1 SYNE2 NIPBL ADGRL3 PCNT NIN	3.46e-11	200	179	12	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	TPR IQGAP2 CNTRL RB1CC1 TTC3 GCC2 SYNE2 OSBPL1A EEA1 NIPBL GOLGB1	5.57e-10	199	179	11	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RALGAPA1 CDK17 TRAF1 TRPM7 DGKH RB1CC1 TASOR2 SYNE2 NIPBL GOLGB1	4.99e-09	188	179	10	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	TET2 TPR RB1CC1 TTC3 DST GCC2 SYNE2 EEA1 NIPBL GOLGB1	8.61e-09	199	179	10	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	TPR CTNNAL1 PPFIBP1 RB1CC1 TTC3 GCC2 SYNE2 EEA1 NIPBL GOLGB1	8.61e-09	199	179	10	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	severe-dn_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TRAF1 FAM184A TRAF5 NUCB2 IBTK FAT1 SYNE2 SEPTIN1 AGMAT	1.05e-07	196	179	9	14baf176bce5750ef50d6838b748caf68c151e05
ToppCell	(04)_Interm._basal>secr.-(2)_GFP_FOXI1\|(04)_Interm._basal>secr. / shred by cell type by condition	IQGAP2 RB1CC1 TTC3 GCC2 SYNE2 OSBPL1A EEA1 NIPBL GOLGB1	1.20e-07	199	179	9	53ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-dn_T\|COVID-19_Severe / Disease, condition lineage and cell class	TRAF1 FAM184A TRAF5 NUCB2 CCDC141 IBTK SYNE2 SEPTIN1 AGMAT	1.25e-07	200	179	9	d01aa5fccada22f97d8350ad5888df2aadb5bb1c
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	RALGAPA1 CDK17 ACAP1 TRAF1 RADX DGKH SYNE2 VPS13A	7.30e-07	181	179	8	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR CNTRL FCHO2 TEP1 GCC2 NFKBIA NIPBL NIN	7.61e-07	182	179	8	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	PRUNE2 TRAF5 ARHGEF28 LAMA3 DGKH ARHGAP6 HMCN2 ADGRL3	7.93e-07	183	179	8	818fd886e0188091310825f9145fa53328f2c979
ToppCell	Control-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RASGRP4 LAMA3 TEP1 SPAG5 HINFP ZNF470 DRC3	8.39e-07	127	179	7	556aaf88719c83f307fa50dfac151136ed05c8ad
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	PRUNE2 TRAF5 ARHGEF28 LAMA3 CLASP2 HMCN2 MID1 ADGRL3	9.71e-07	188	179	8	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-Tregs\|Lung / Manually curated celltypes from each tissue	ACAP1 TRAF1 FAM184A CCDC141 ATP8B2 SYNE2 SEPTIN1 AGMAT	9.71e-07	188	179	8	604f340052807bd902915eca942a97ccc36b42e0
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL6 PDS5B TPR CNTRL KIF15 TMPRSS3 SEC63 NIPBL	1.23e-06	194	179	8	8ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTNNAL1 ZNF423 ZNF521 DGKH PLEKHG1 DST HMCN1 ADGRL3	1.23e-06	194	179	8	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	severe-dn_T\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TRAF1 FAM184A TRAF5 NUCB2 IBTK FAT1 SEPTIN1 AGMAT	1.43e-06	198	179	8	d4f2213af45ada47e6c62675f468ce05692db507
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	CNTRL RB1CC1 TTC3 GCC2 SYNE2 EEA1 NIPBL GOLGB1	1.49e-06	199	179	8	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	(00)_Basal-(2)_GFP_FOXI1\|(00)_Basal / shred by cell type by condition	CTNNAL1 RB1CC1 TTC3 GCC2 SYNE2 EEA1 NIPBL GOLGB1	1.49e-06	199	179	8	19674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	RB1CC1 TTC3 GCC2 SYNE2 EEA1 SEC63 NIPBL GOLGB1	1.49e-06	199	179	8	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	CNTRL SPAG5 BRCA1 KIF15 NDC80 SYNE2 CEP135 CEP152	1.54e-06	200	179	8	0d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCell	Control-Control-Myeloid-immature_Neutrophil\|Control / Disease, condition lineage and cell class	KLHL6 NUCB2 GEMIN5 SPAG5 ANKRD20A4P KIF15 VPS13A PCNT	1.54e-06	200	179	8	118321ac443feb42aee171baccfc4610f00a8822
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells\|2m / Sample Type, Dataset, Time_group, and Cell type.	CNTRL SPAG5 BRCA1 KIF15 NDC80 SYNE2 CEP135 CEP152	1.54e-06	200	179	8	0675f580ccef705875854247bbfd4ee2bcf126a1
ToppCell	ICU-SEP-Lymphocyte-T_NK-Treg\|ICU-SEP / Disease, Lineage and Cell Type	ANKRD31 TPR TRAF1 OBSCN CCDC141 FSIP2 SYNE2	2.04e-06	145	179	7	ee99b58462f955b96d036aa67e343db047d66f64
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SYNE1 ZNF423 LAMA3 CCDC168 SRCIN1 RAPGEF3	3.61e-06	158	179	7	e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SYNE1 ZNF423 LAMA3 CCDC168 SRCIN1 RAPGEF3	3.61e-06	158	179	7	d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRAF1 CTNNAL1 DGKH CCDC141 ATP8B2 NDC80 SYNE2	8.49e-06	180	179	7	6bb9f41c3a99d1bbe697f589fb2bcea9b7bfbeee
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	PRUNE2 TRAF5 ARHGEF28 LAMA3 DGKH HMCN2 MID1	9.45e-06	183	179	7	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 PPFIBP1 LRRK2 SERPINA1 FAT1 SYNE2 VPS13A	9.80e-06	184	179	7	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR CNTRL FCHO2 SETD2 GCC2 NFKBIA NIPBL	9.80e-06	184	179	7	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	Control-immature_Neutrophil-\|Control / Disease condition and Cell class	NUCB2 GEMIN5 SPAG5 ANKRD20A4P KIF15 VPS13A PCNT	9.80e-06	184	179	7	c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCell	Control-immature_Neutrophil\|Control / Disease condition and Cell class	NUCB2 GEMIN5 SPAG5 ANKRD20A4P KIF15 VPS13A PCNT	9.80e-06	184	179	7	2fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCell	10x5'-blood-Lymphocytic_T_CD4-Tregs\|blood / Manually curated celltypes from each tissue	ACAP1 TRAF1 FAM184A DGKH CCDC141 ATP8B2 SYNE2	9.80e-06	184	179	7	22c15ce30171c687ab564f4383ae74d38b759272
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR CNTRL FCHO2 GCC2 NFKBIA NIPBL NIN	1.01e-05	185	179	7	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	Control-Lymphoid-Tregs\|Control / Condition, Lineage and Cell class	ACAP1 FAM184A SYNE1 CCDC141 ATP8B2 SYNE2 SEPTIN1	1.05e-05	186	179	7	6144f32a370594e45b91da142b4f435370c69b9a
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	RASGRP4 ZNF423 HDAC7 ATP8B2 FMNL3 HMCN2 RAPGEF3	1.13e-05	188	179	7	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 PPFIBP1 LRRK2 FAT1 SYNE2 MID1 ADGRL3	1.17e-05	189	179	7	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	PRUNE2 TRAF5 ARHGEF28 LAMA3 HMCN2 MID1 ADGRL3	1.17e-05	189	179	7	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	BAL-Control-Lymphocyte-T/NK-CD4+_T-Treg-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ACAP1 FAM184A CCDC141 ATP8B2 PLEKHG1 SYNE2 SEPTIN1	1.21e-05	190	179	7	c3c7de22657a86495939456bc22eac61c93db8b2
ToppCell	BAL-Control-Lymphocyte-T/NK-CD4+_T-Treg\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ACAP1 FAM184A CCDC141 ATP8B2 PLEKHG1 SYNE2 SEPTIN1	1.21e-05	190	179	7	166119c037d80fee852567a9cc53c4143dd19037
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	C22orf42 PEG10 ZNF521 LRRTM1 SYT16 ZFHX3 ADGRL3	1.21e-05	190	179	7	6e92c78799f34b31d098854503c796edb0dc7f80
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR CNTRL RB1CC1 STIM1 SYNE2 AKAP11 GOLGB1	1.25e-05	191	179	7	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	Adult-Immune-T_lymphocyte-D175\|Adult / Lineage, Cell type, age group and donor	ACAP1 TRAF1 TRAF5 IQGAP2 ATP8B2 SYNE2 FGD3	1.25e-05	191	179	7	0b84fd1dc68146d9f72422b102744d2847f5ecb2
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR CNTRL RB1CC1 STIM1 SYNE2 AKAP11 GOLGB1	1.25e-05	191	179	7	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	Control-Lymphoid_T/NK-Treg\|Control / Disease group, lineage and cell class	ACAP1 TRAF1 FAM184A DGKH CCDC141 ATP8B2 SYNE2	1.34e-05	193	179	7	715f2bbee12a7952cba85d9cd8820411983ce790
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTNNAL1 ZNF423 ZNF521 DGKH PLEKHG1 HMCN1 ADGRL3	1.34e-05	193	179	7	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARHGEF28 PEG10 RB1CC1 GCC2 PLAGL1 NIPBL GOLGB1	1.34e-05	193	179	7	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 SYNE1 LRRK2 LAMA3 DGKH SYT16 SYNE2	1.38e-05	194	179	7	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ZYG11B RB1CC1 TTC3 SPTBN4 AKAP11 HERC2 CEP170B	1.38e-05	194	179	7	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	LPS-IL1RA-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTNNAL1 ZNF423 ZNF521 DGKH PLEKHG1 DST ADGRL3	1.38e-05	194	179	7	43f92b0533e26633dc94cce554045d641ef8fd76
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PEG10 NUCB2 FAM114A2 ZSWIM1 BRCA1 SEPTIN1 AGMAT	1.38e-05	194	179	7	5031f324628ff12a33e84cc52157be4786e0961d
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ACAP1 TRAF1 FAM184A DGKH CCDC141 ATP8B2 SYNE2	1.38e-05	194	179	7	2faf49d85d09932c9c20d9f675c8093ad802fae5
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ACAP1 TRAF1 FAM184A DGKH CCDC141 ATP8B2 SYNE2	1.38e-05	194	179	7	fd3d5ac94de3db7136684c86f8589631ad87e6d8
ToppCell	LPS-IL1RA-Endothelial-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTNNAL1 ZNF423 ZNF521 DGKH PLEKHG1 DST ADGRL3	1.38e-05	194	179	7	1d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 PPFIBP1 LRRK2 FBXL21P SERPINA1 FAT1 SYNE2	1.38e-05	194	179	7	8ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ACAP1 OBSCN DGKH TTC3 ATP8B2 GCC2 SYNE2	1.43e-05	195	179	7	4bdedd924564a260841a9153604026b57487c83d
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ACAP1 DGKH ATP8B2 DST GCC2 SYNE2 SEPTIN1	1.43e-05	195	179	7	22191d361af136942508f1553ff41a626ed982ad
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CDK17 ABR ZNF423 ZNF521 FMNL3 PLEKHG1 STARD9	1.48e-05	196	179	7	b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CDK17 ABR ZNF423 ZNF521 FMNL3 PLEKHG1 STARD9	1.48e-05	196	179	7	d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCell	COVID_non-vent-Lymphocytic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ACAP1 SYNE1 TTC3 ATP8B2 GCC2 SYNE2 SEPTIN1	1.52e-05	197	179	7	c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	PAK4 ANKRD20A2P DGKH ANKRD20A3P ARHGAP6 ANKRD20A4P EXOSC7	1.52e-05	197	179	7	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	Control_saline-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	FAM184A ARHGEF28 VEPH1 LRRK2 LAMA3 CCDC141 FAT1	1.52e-05	197	179	7	44a59dfb889577b3160a5b13ada1276771a00241
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ARHGEF28 SYNE1 DGKH ABCA5 STARD9 SYNE2 VPS13A	1.52e-05	197	179	7	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAM184A SYNE1 SRCIN1 SYNE2 DLEC1 CPLANE1 DRC3	1.52e-05	197	179	7	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-Treg\|ICU-SEP / Disease, condition lineage and cell class	ANKRD31 TPR TRAF1 OBSCN CCDC141 FSIP2 SYNE2	1.52e-05	197	179	7	c3ee2d522fbfe67069ddba2d1abfc4f5ca230c26
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ARHGEF28 VEPH1 LRRK2 LAMA3 CCDC141 FAT1 ABCA5	1.58e-05	198	179	7	285f729140b1df029c24f6ca1d2438470ac51794
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-Treg\|ICU-NoSEP / Disease, condition lineage and cell class	ACAP1 PPFIBP1 ARHGEF10 SYNE2 OSBPL1A SEPTIN1 MAP4K2	1.58e-05	198	179	7	1ed4dfe5565328cb0f7ef31e6b2f67dfbdf3e2ac
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	CNTRL RB1CC1 TTC3 GCC2 SYNE2 NIPBL GOLGB1	1.58e-05	198	179	7	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RALGAPA1 CDK17 SYNE1 ABCA5 SYNE2 VPS13A GOLGB1	1.63e-05	199	179	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Influenza-Influenza_Severe-Lymphocyte-T/NK-NK_CD56bright\|Influenza_Severe / Disease, condition lineage and cell class	TRAF1 TRAF5 ARHGEF28 PSD ABCA5 ARHGEF10 ZNF470	1.63e-05	199	179	7	784e7e7ede2baa28ede600834813e6de2240bfdf
ToppCell	Control-Control-Lymphocyte-T/NK-Treg\|Control / Disease, condition lineage and cell class	ACAP1 TRAF1 FAM184A DGKH CCDC141 ATP8B2 SYNE2	1.63e-05	199	179	7	6b7eb14bf03aa05f2d4ac4f5dd1ccf41a7e47bd1
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAM184A PEG10 SYNE1 VEPH1 LRRK2 FCHO2 CCDC141	1.63e-05	199	179	7	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	ZNF326 RB1CC1 TTC3 GCC2 SYNE2 EEA1 GOLGB1	1.63e-05	199	179	7	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CNTRL SPAG5 BRCA1 KIF15 NDC80 SYNE2 CEP152	1.63e-05	199	179	7	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CNTRL SPAG5 BRCA1 KIF15 NDC80 SYNE2 CEP152	1.63e-05	199	179	7	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T\|COVID-19_Mild / Disease, condition lineage and cell class	TRAF1 FAM184A TRAF5 CNTRL NUCB2 CCDC141 SYNE2	1.63e-05	199	179	7	f307d4887b28cf60a591439e278fd668409cb104
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ARHGEF28 DGKH DST SYNE2 CPLANE1 HECTD1 GOLGB1	1.68e-05	200	179	7	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	Transverse-Dendritic_cell-cycling_DCs\|Dendritic_cell / Region, Cell class and subclass	NUCB2 BRCA1 KIF15 NDC80 ASGR1 OSBPL1A SLC35F6	1.68e-05	200	179	7	617a6a42f7b31eb3c45bdceaf55a591b6de7f154
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 TPR SETD2 NFKBIA SYNE2 NIPBL GOLGB1	1.68e-05	200	179	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CTNNAL1 ARHGEF28 ARHGAP6 ARHGEF10 GCC2 OSBPL1A MAP4K2	1.68e-05	200	179	7	7034f57e282982c19c13ee8ab78eabaffa069e30
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CTNNAL1 DGKH ITPRID2 HDAC7 DST SYNE2 ADGRL3	1.68e-05	200	179	7	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARHGEF28 DGKH DST SYNE2 CPLANE1 HECTD1 GOLGB1	1.68e-05	200	179	7	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CTNNAL1 SPAG5 BRCA1 KIF15 NDC80 CEP152 PCNT	1.68e-05	200	179	7	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-7\|TCGA-Brain / Sample_Type by Project: Shred V9	OR7E24 LRRK2 ANKRD20A3P ANKRD20A8P KIF15 NDC80	1.87e-05	136	179	6	d94f0fbeb7b80d4cf0687d1924ebf8f9dd07358c
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAM184A TRAF5 NUCB2 IBTK SYNE2 AGMAT	3.50e-05	152	179	6	405d19b290232bb3e564d61c0cff0cfdd247bdff
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAM184A TRAF5 NUCB2 IBTK SYNE2 AGMAT	3.50e-05	152	179	6	06fa7d8acc8f56de00af9bee17884595b300410e
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	FAM184A TRAF5 NUCB2 IBTK SYNE2 AGMAT	3.63e-05	153	179	6	b101cb1bce5db785dab46b6c4f7be9c3efe48b0e
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FAM184A TRAF5 NUCB2 IBTK SYNE2 AGMAT	3.63e-05	153	179	6	487388082bb596809ba1caf9197626b6814792ab
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TPR TRAF1 DGKH CCDC141 ATP8B2 SYNE2	3.63e-05	153	179	6	7480522a47e367f8facc4f5d599fbaf0b5ad4007
ToppCell	COVID-19_Severe-Lymphoid_T/NK-dn_T\|COVID-19_Severe / Disease group, lineage and cell class	FAM184A TRAF5 NUCB2 IBTK SYNE2 AGMAT	4.04e-05	156	179	6	83f25683e0f55472b56f915ee176fc05efc33a31
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TPR TRAF1 DGKH CCDC141 ATP8B2 SYNE2	4.04e-05	156	179	6	53ded973358e3e48054130131e959f0d1f4ef60f
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	RALGAPA1 CDK17 TRAF1 FAM184A DGKH SYNE2	4.04e-05	156	179	6	1545169694f686d28648a68b552c2ae606599d66
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	PRUNE2 LAMA3 DGKH HMCN2 ZFHX3 ADGRL3	4.82e-05	161	179	6	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NUCB2 CASP6 SYNE2 TJAP1 DLEC1 HERC2	4.82e-05	161	179	6	5fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-EECs\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYCN C22orf42 PSD SRCIN1 SPTBN4 PMFBP1	4.99e-05	162	179	6	478cf560ef33c5c324142c76417447d4a571a2c9
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh\|GI_large-bowel / Manually curated celltypes from each tissue	PDS5B CDK16 FAM184A ALPK1 ATP8B2 PRMT9	5.16e-05	163	179	6	4104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	MIA3 OBSCN QTRT2 SETD2 ZNF33A CPLANE1	5.71e-05	166	179	6	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	3'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRIML2 ZNF423 CPT1B SERPINA1 ANKEF1 ODAD3	6.11e-05	168	179	6	2163e6774eb7a3d010422e4d59be5e45b4158329
ToppCell	Control\|World / group, cell type (main and fine annotations)	FAM184A ARHGEF28 SYNE1 VEPH1 LAMA3 CCDC141	6.11e-05	168	179	6	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	facs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUCB2 TLR7 RSC1A1 ABCA5 ARHGEF10 AGMAT	6.73e-05	171	179	6	6a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
Computational	Genes upregulated in subsets of cells of a given type within various tumors	TASOR2 SETD2 DST SYNE2 GOLGB1	7.13e-05	50	94	5	GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Drug	Clorgyline	RB1CC1 IBTK DST ABCA5 GCC2 CEP135 VPS13A AKAP11 NIPBL GOLGB1	8.58e-07	168	178	10	ctd:D003010
Disease	Malignant neoplasm of breast	ACAP1 VPS39 SYNE1 OBSCN MED14 NBN JAKMIP3 RB1CC1 TTC3 HDAC7 GGA3 SETD2 BRCA1 ANKEF1 NFKBIA SYNE2 DLEC1 HERC2 NIPBL GOLGB1 DOP1A	1.09e-06	1074	170	21	C0006142
Disease	colorectal cancer (is_marker_for)	TET2 HDAC7 SETD2 SERPINA1 BRCA1 NDC80 ZFHX3	3.67e-05	157	170	7	DOID:9256 (is_marker_for)
Disease	Seckel syndrome 1	CEP152 PCNT	9.86e-05	3	170	2	C4551474
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	1.96e-04	4	170	2	cv:CN293514
Disease	haptoglobin measurement	ZFHX3 PMFBP1 PHLPP2	2.32e-04	21	170	3	EFO_0004640
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	3.26e-04	5	170	2	C1450051
Disease	DnaJ homolog subfamily B member 9 measurement	SERPINA1 PMFBP1	3.26e-04	5	170	2	EFO_0801540
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	3.26e-04	5	170	2	C0410190
Disease	platelet component distribution width	PRUNE2 PDS5B IQGAP2 SYNE1 SDCCAG8 LRRK2 HDAC7 STIM1 SETD2 RAPGEF3 GCC2 DLEC1 FGD3	4.57e-04	755	170	13	EFO_0007984
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	4.88e-04	6	170	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	4.88e-04	6	170	2	C0410189
Disease	heparin cofactor 2 measurement	PMFBP1 PHLPP2	6.80e-04	7	170	2	EFO_0008150
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	6.80e-04	7	170	2	C0751337
Disease	Ovarian Mucinous Adenocarcinoma	NRBP1 LRRK2 ALPK1	7.50e-04	31	170	3	C1335167
Disease	mean platelet volume	TET2 PDS5B IQGAP2 PCDHGA11 SDCCAG8 NUCB2 LRRK2 FCHO2 HDAC7 STIM1 SETD2 GCC2 SYNE2 FGD3 NIN	8.64e-04	1020	170	15	EFO_0004584
Disease	Sarcomatoid Renal Cell Carcinoma	TET2 LRRK2 SPTBN4 SETD2 SYNE2	8.95e-04	128	170	5	C1266043
Disease	Chromophobe Renal Cell Carcinoma	TET2 LRRK2 SPTBN4 SETD2 SYNE2	8.95e-04	128	170	5	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	TET2 LRRK2 SPTBN4 SETD2 SYNE2	8.95e-04	128	170	5	C1266044
Disease	Papillary Renal Cell Carcinoma	TET2 LRRK2 SPTBN4 SETD2 SYNE2	8.95e-04	128	170	5	C1306837
Disease	Renal Cell Carcinoma	TET2 LRRK2 SPTBN4 SETD2 SYNE2	8.95e-04	128	170	5	C0007134
Disease	cerebellar ataxia (implicated_via_orthology)	GEMIN5 VPS13A	9.03e-04	8	170	2	DOID:0050753 (implicated_via_orthology)
Disease	sick sinus syndrome	CCDC141 ZFHX3	9.03e-04	8	170	2	MONDO_0001823
Disease	familial sick sinus syndrome	CCDC141 ZFHX3	9.03e-04	8	170	2	MONDO_0012061
Disease	nephronophthisis (implicated_via_orthology)	SDCCAG8 CNTRL	1.16e-03	9	170	2	DOID:12712 (implicated_via_orthology)
Disease	pulse pressure measurement	TET2 TRAF1 TRPM7 ZNF423 SDCCAG8 CNTRL NUCB2 CCDC141 FMNL3 SPTBN4 PLEKHG1 KIF15 NFKBIA SLX4IP ZFHX3 DLEC1 MAP4K2 NIN	1.17e-03	1392	170	18	EFO_0005763
Disease	stomach cancer (is_marker_for)	TET2 STIM1 SETD2 BRCA1 NDC80	1.42e-03	142	170	5	DOID:10534 (is_marker_for)
Disease	physical activity	ZNF521 CCDC27 PLEKHG1 NIPBL	1.70e-03	88	170	4	EFO_0003940
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	TET2 LRRK2 SPTBN4 SETD2 SYNE2	1.70e-03	148	170	5	C0279702
Disease	gastrointestinal stromal tumor (is_implicated_in)	STIM1 SETD2	1.75e-03	11	170	2	DOID:9253 (is_implicated_in)
Disease	nevus count, cutaneous melanoma	MIA3 TASOR2 SYNE2 HERC2	1.93e-03	91	170	4	EFO_0000389, EFO_0004632
Disease	FEV/FEC ratio	KLHL6 TET2 FAM184A ARHGEF28 ABR CES5A ADAMTS2 STIM1 SERPINA1 DST KIF15 HMCN1 NFKBIA SYNE2 ZFHX3 DLEC1	2.04e-03	1228	170	16	EFO_0004713
Disease	Diabetic Nephropathy	MYCN DGKH ALPK1	2.09e-03	44	170	3	C0011881
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	2.10e-03	12	170	2	DOID:11726 (implicated_via_orthology)
Disease	microphthalmia (implicated_via_orthology)	ARHGAP6 MID1	2.10e-03	12	170	2	DOID:10629 (implicated_via_orthology)
Disease	esophagus squamous cell carcinoma (is_implicated_in)	TET2 FAT1 BRCA1	2.23e-03	45	170	3	DOID:3748 (is_implicated_in)
Disease	Adenoid Cystic Carcinoma	MYCN SETD2 FAT1 BRCA1	2.71e-03	100	170	4	C0010606
Disease	Hereditary Breast and Ovarian Cancer Syndrome	NBN BRCA1	2.87e-03	14	170	2	C0677776
Disease	lung non-small cell carcinoma (is_marker_for)	CASP6 STIM1 BRCA1 NDC80 ZFHX3	3.03e-03	169	170	5	DOID:3908 (is_marker_for)
Disease	Autosomal recessive primary microcephaly	CEP135 CEP152	3.30e-03	15	170	2	cv:C3711387
Disease	nasopharynx carcinoma (is_implicated_in)	TET2 BRCA1	3.30e-03	15	170	2	DOID:9261 (is_implicated_in)
Disease	calcium measurement	ANKRD31 TET2 FCHO2 STIM1 HINFP SERPINA1 SYNE2 SHOC1 ZFHX3 GOLGB1	3.61e-03	628	170	10	EFO_0004838
Disease	muscular dystrophy (is_implicated_in)	SYNE1 POMGNT1	4.24e-03	17	170	2	DOID:9884 (is_implicated_in)
Disease	sphingomyelin 14:0 measurement	SYNE2 ZFHX3	4.24e-03	17	170	2	EFO_0010390
Disease	serum hepcidin measurement	DGKH AKAP11	4.75e-03	18	170	2	EFO_0004504
Disease	prostate cancer (is_implicated_in)	NBN BRCA1 NFKBIA ZFHX3	4.76e-03	117	170	4	DOID:10283 (is_implicated_in)
Disease	Varicose veins	PPFIBP1 HDAC7 FMNL3 ARHGAP6 COG6	5.32e-03	193	170	5	HP_0002619
Disease	colorectal cancer (is_implicated_in)	STIM1 SETD2 FAT1 BRCA1	5.36e-03	121	170	4	DOID:9256 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
STLVLHDLLKHTPVD	ABR	246	Q12979
EVISRITHALDLKEH	ABCA5	1411	Q8WWZ7
TSLAEKLLSHGAHIE	ANKRD20A1	146	Q5TYW2
LSEDHSSLLLHVKQF	ASGR1	116	P07306
HTETLKHLQDINIAT	ARHGEF10	1136	O15013
LESLKQQLVDLHHSE	CEP152	336	O94986
EDHHLQVLKESEVLL	CNTRL	1561	Q7Z7A1
DLLHTTKHQDVLLSE	CNTRL	1886	Q7Z7A1
EELVLSIQHHKSNVS	PRMT9	826	Q6P2P2
TSLAEKLLSHGAHIE	ANKRD20A8P	146	Q5CZ79
HLENELTHDIITKFL	SERPINA1	286	P01009
TSLAEKLLSHGAHIE	ANKRD20A4P	146	Q4UJ75
EETHLIHIKEIIGSL	FCHO2	206	Q0JRZ9
VEVKHSDAVHDLLLD	ADGRL3	851	Q9HAR2
LDTFLHQKHQLETTD	AKAP11	156	Q9UKA4
SSEQLAAIAHLHEKT	ANKEF1	371	Q9NU02
HALTLLSEVLAHLLD	DOP1A	2036	Q5JWR5
LDSHAELLDATQHTL	ACAP1	91	Q15027
HSQDTHLILKETETA	CEP170B	906	Q9Y4F5
KHDHHLVEDLSESLS	C22orf42	161	Q6IC83
LDKEVQHLHENISAL	FAM184A	886	Q8NB25
QHLHENISALTKELE	FAM184A	891	Q8NB25
VDATSHHLAVKNLET	ADAMTS2	756	O95450
SLLKEFDHHLLSAAE	ALPK1	266	Q96QP1
ADTILLDRLHHSTQE	ATP8B2	581	P98198
SLLKAFSRHEEELQH	CCDC27	301	Q2M243
ILESGHLRKLDHISE	POLL	316	Q9UGP5
LHKSLDPSNLEHLIT	PDS5B	751	Q9NTI5
HEVSLIADSQKSHLI	PCDHGA11	756	Q9Y5H2
TLNLHELHEDTLEKL	MAP4K2	511	Q12851
HNFSDTKIISLSHLE	RADX	211	Q6NSI4
TSLAEKLLSHGAHIE	ANKRD20A2P	146	Q5SQ80
LTLNHTAEHLLEADI	ARHGEF28	251	Q8N1W1
LLTHEASKLTNHVEL	ANKRD31	1016	Q8N7Z5
SHLKELEDTLQVRHI	RB1CC1	986	Q8TDY2
TLILVDHHILSKSDT	PRUNE1	101	Q86TP1
TSEKLDHEAVHQHTL	FAT1	1516	Q14517
EELTSALVHLKLHLF	SLC10A7	61	Q0GE19
LLHLLQHQDSEVLSD	KPNA7	246	A9QM74
ELAALQKLEHLSVSH	FLII	51	Q13045
LDLPVDTLHHILKSD	KLHL6	211	Q8WZ60
VTIKQHILHLELDTD	LAMA3	3246	Q16787
HDLRVVLHSADKELS	KIF15	801	Q9NS87
LTATHLLFIDSHQKE	MTMR6	31	Q9Y217
DDLLSLKVVSVLHHL	PPFIBP1	756	Q86W92
LTELHLEHNDLVKVN	LRRTM1	211	Q86UE6
QDIQLSSKHTHITLD	HERC2	4611	O95714
QVSALHHKDIALSLV	IBTK	331	Q9P2D0
HVEELSISHQSLKTA	DST	3471	Q03001
EVLHSLLKEISSHGL	DST	4321	Q03001
AIQASKVHLLSTDHE	HMCN2	211	Q8NDA2
LLLKIHEVSTVSHAD	CASP6	96	P55212
HHIQSFLSEDKTLLL	FSIP2	4906	Q5CZC0
GTLLLLIKEDHNLHE	OR51B5	41	Q9H339
IVHESERLEALKHAL	COPS4	216	Q9BT78
HDKHSLTEIRDSLLD	CES5A	391	Q6NT32
LGVHLKDLVSLHEAQ	RASGRP4	351	Q8TDF6
LIGHLKDSTHNDIIL	VEPH1	241	Q14D04
VHSLNQVSTDHIELK	NIPBL	66	Q6KC79
SDHIQEELSHLEVAK	PEG10	211	Q86TG7
REHEQHKTAVLLTEL	JAKMIP3	61	Q5VZ66
EHLEKLELHQNALTS	LRRK2	1011	Q5S007
SALHHLDALDQLLEE	GGA3	511	Q9NZ52
SFLHLAIIHEEKALT	NFKBIA	76	P25963
AHGLLEELKTVLSSH	GCN1	601	Q92616
VTLHDIVHTDKSLTL	CDK17	251	Q00537
QKLLHIAQELLHTEE	FGD3	156	Q5JSP0
SVATHLTKILNSDEH	DGKH	491	Q86XP1
ELDLVSHHVRTKLDE	NUCB2	91	P80303
KILSEALETLATEHH	OSBPL1A	441	Q9BXW6
LHASLQSVVHKEESL	EXOSC7	266	Q15024
HSELENSSELKSVHI	ITPRID2	426	P28290
QLHEVIEKLQHELSL	PCNT	1741	O95613
VQASKVHLLSTDHLE	HMCN1	216	Q96RW7
SIEKLLIDSVHARAH	MED14	396	O60244
IESVEEGVKHHLTLL	NRBP1	451	Q9UHY1
HLLTLHKVTLEDAGT	OBSCN	4306	Q5VST9
DLFSSLKHIQHTLVD	PALS1	126	Q8N3R9
LEEEHSVHDVAALLK	ARHGAP6	456	O43182
QLTLSSLAEHHEVLT	QTRT2	61	Q9H974
KHHITLTNLITEETT	BRCA1	1671	P38398
HSHLTSHEKDTEIQL	CEP135	1046	Q66GS9
HQATASEKEHLEALL	COG6	316	Q9Y2V7
SETSLHRIHVELSEK	EEA1	356	Q15075
TSLAEKLLSHGAHIE	ANKRD20A3P	146	Q5VUR7
ICVESLSSLLKHEDH	HECTD1	186	Q9ULT8
STHQLEVHIESKHDE	BMP10	216	O95393
SQDETKKLLHDHELL	CCDC141	56	Q6ZP82
EHHTKELLERSLALL	CCDC141	171	Q6ZP82
ISHSLNELKKELHST	CTNNAL1	386	Q9UBT7
IHKILHESHNSLLQD	CPLANE1	3126	Q9H799
LHDIIHTEKSLTLVF	CDK16	226	Q00536
EEESEIVKLLTNTHH	DHX57	416	Q6P158
LEEHVSHLTEKLLDL	FMNL3	401	Q8IVF7
HLEDTLKELESQHSI	GCC2	336	Q8IWJ2
HVLKHLQVETLTQED	CYP11B1	466	P15538
KSSISDILLHHLSKE	AKNAD1	106	Q5T1N1
EISLIENKIESHRHE	FAM114A2	481	Q9NRY5
LEENHEIISHIKDSV	MAN2A2	61	P49641
NKELALHIHTDIDSQ	MAN2A2	881	P49641
SLVESHLSDQLTLHV	EMC10	136	Q5UCC4
HERKDISDIALHLIS	CCDC168	531	Q8NDH2
HHHEKLLEISISTLE	DRC3	411	Q9H069
KASLEELQSVHSERH	HDAC7	571	Q8WUI4
LIDLQKHLDTHSEEP	HINFP	296	Q9BQA5
LELTAHTQEELTHLA	DLEC1	1036	Q9Y238
VLSELVTTHHLKLTN	DLEC1	1496	Q9Y238
SEKKEHLSLQDLSDH	RSC1A1	66	Q92681
TTSLRDLQELEELHH	MAP3K19	831	Q56UN5
KDTDVLQHLSDSRHV	CPT1B	321	Q92523
EAEHLKHLNSILVLD	LRRC40	281	Q9H9A6
VIHRDIKSDSILLTH	PAK4	436	O96013
LFLALSSETHVNLEH	FBXL21P	246	Q9UKT6
SILEKQTSDLVLLHH	PMFBP1	116	Q8TBY8
STEVLLDHLKAHAEE	PLAGL1	131	Q9UM63
SLLHLSLLHLEEDKT	SPAG5	516	Q96R06
TTHNLDENELKTEHT	PRUNE2	1046	Q8WUY3
LLDLNDISSALKHHE	PPP1R3C	116	Q9UQK1
TELKNAISIHHALAT	PSD	811	A5PKW4
VLSSIAEEEHHLEKQ	SYT16	136	Q17RD7
LEHELQKHVSRQDTL	SYNE1	4031	Q8NF91
HSNLEELHSLVATLD	SYNE1	5046	Q8NF91
LEDSEQKHNLLHSIF	SYNE2	3831	Q8WXH0
LHTLSVEHQREELKE	MIA3	606	Q5JRA6
HQEQLTSLVEKHTLE	NIN	766	Q8N4C6
SDLIAHHARKNTELE	NBN	706	O60934
SEHQLHLTRQEKDSI	SDCCAG8	531	Q86SQ7
SIEEIISTHSLLLEH	IQGAP2	1211	Q13576
LLIILAVSSDSHLHT	OR7E24	61	Q6IFN5
KTHREHLLLQSDDTI	ODAD3	321	A5D8V7
HLLLQSDDTIQDSLH	ODAD3	326	A5D8V7
LEHLASKLIHITVED	ODAD3	466	A5D8V7
HRLLSEAEVLDHSKN	POMGNT1	546	Q8WZA1
LEHKSHSSPIALIDE	SHOC1	411	Q5VXU9
LLHVDAHTDTTDKAL	AGMAT	181	Q9BSE5
LSLSVELTEAKLHHG	STARD9	4206	Q9P2P6
AEEVVALLHTLHSLT	HERC2P3	856	Q9BVR0
LDHDIIDLEQTATHL	MRPS2	111	Q9Y399
VAHSSSLDDVDHKIL	STIM1	396	Q13586
KEELHVLESLSSRHL	SLX4IP	356	Q5VYV7
LAVLEEETNKHDTHI	TRAF5	366	O00463
HSDLVAELLKELSNH	CLASP2	1056	O75122
QTHLQDLKEVTHDLL	SEPTIN1	276	Q8WYJ6
SIDHLLPDDKVTALH	TMPRSS3	171	P57727
ELEDKLHTLASLSHS	TJAP1	111	Q5JTD0
SKSLLLEHLEPAHIT	TRIML2	216	Q8N7C3
IFEELLHIKAVAHLS	RAPGEF3	236	O95398
DVVRELKHLNHLDIS	ZYG11B	231	Q9C0D3
KDFIDHISSLLHSVE	ZYG11B	581	Q9C0D3
DIHILEVTNNLEHKS	ZBTB5	391	O15062
LIKVNFSSLDIHLHT	VPS13A	986	Q96RL7
DEKLHHSVLQTPDDL	RALGAPA1	1021	Q6GYQ0
LEKLHQHVSTHSDIL	TEP1	31	Q99973
HSLQAEEHQLLLEKE	MYCN	431	P04198
LEHKTLDIFSHITTL	PHLPP2	751	Q6ZVD8
ITHEVSSLDTLHALI	SRCIN1	196	Q9C0H9
RLSSQIEKLEHEISH	TPR	836	P12270
LDSFQTHLKTHLDTV	ZNF521	646	Q96K83
SLISQAEHSLKENDH	MID1	311	O15344
LSTSLDHRSKEELHQ	GEMIN5	851	Q8TEQ6
KEHELHLDQSLEISN	TTC3	1596	P53804
ITHIDTLIEKRDHSN	ZNF470	161	Q6ECI4
DLVSLKESDRHTLLH	SEC63	411	Q9UGP8
KEVEASHLALATSIH	TRAF1	206	Q13077
LLASKELHQVAHDLD	SPTBN4	1511	Q9H254
LLHSTAFEELHKLEV	TLR7	556	Q9NYK1
ITHDSHDSIKELDSL	SETD2	641	Q9BYW2
ADLLSKHDSQHKLSE	SLC35F6	161	Q8N357
HHEETLQHEKIQTLE	ZNF33A	201	Q06730
TLKAARHLDSVLSDH	WASHC4	966	Q2M389
LSHSQLTEELVASLH	ZBED9	531	Q6R2W3
EDISSHLHQIPSLLK	TASOR2	2236	Q5VWN6
HLLLHEIENHLDKDT	PLEKHG1	256	Q9ULL1
SLAVLEIHLKTIHAD	ZNF423	421	Q2M1K9
HKLIHAASERVLSDA	UBAC1	61	Q9BSL1
LSDLERHSISHSELK	ZNF524	126	Q96C55
LQVLVHKSHDLLQEE	XPO6	1031	Q96QU8
HKSHDLLQEEIGIAI	XPO6	1036	Q96QU8
TLDKHLAVTHLTEEV	ZSWIM1	436	Q9BR11
SSVEHTHGELLEKTL	TET2	216	Q6N021
HQLLQTTKLVEEHLD	TXNDC9	16	O14530
EADLHLTKALTHTVA	WDR87	2856	Q6ZQQ6
LVLKDILHLAEHQET	ZNF772	151	Q68DY9
HNEITRELSISKHLA	TRPM7	1261	Q96QT4
LIGERLSESKESHQH	ZNF878	66	C9JN71
ALQVLELHHSKLDTT	VPS39	771	Q96JC1
ELHHSKLDTTKALNL	VPS39	776	Q96JC1
KHLETSHLELSEADI	ZFHX3	1446	Q15911
LESSSHQETLDHIQK	ZNF326	331	Q5BKZ1
LKTVSHEAEVHAESL	GOLGB1	1356	Q14789
LKALDHHVISDEEII	LRRIQ3	151	A6PVS8
ELESLEKHKHLLEST	NDC80	531	O14777