Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	dendritic spine head	HPCA SYNE1 GRIA2	4.15e-05	16	90	3	GO:0044327
GeneOntologyCellularComponent	nuclear pore	RGPD8 RGPD1 NUP214 NXF1 RGPD5	7.57e-05	101	90	5	GO:0005643
GeneOntologyCellularComponent	nuclear inclusion body	RGPD8 RGPD1 NXF1	8.34e-05	20	90	3	GO:0042405
GeneOntologyCellularComponent	cell projection membrane	HPCA EVC2 TMEM17 CSPG4 TSPEAR GRIA2 FGD5 PLA2G4F RAB8A	1.00e-04	431	90	9	GO:0031253
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RGPD8 RGPD1	5.05e-04	8	90	2	GO:1990723
GeneOntologyCellularComponent	nuclear protein-containing complex	CRNKL1 SALL1 GTF2A1L RGPD8 BRCA2 SYNE1 BACH2 TET1 RGPD1 REL NUP214 SSRP1 NXF1 SYMPK RGPD5	7.52e-04	1377	90	15	GO:0140513
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RGPD8 RGPD1	8.07e-04	10	90	2	GO:0044614
GeneOntologyCellularComponent	ciliary membrane	EVC2 TMEM17 TSPEAR RAB8A	8.52e-04	98	90	4	GO:0060170
Domain	Grip	RGPD8 RGPD1 RGPD5	1.74e-05	11	90	3	SM00755
Domain	GRIP	RGPD8 RGPD1 RGPD5	1.74e-05	11	90	3	PF01465
Domain	Ran_BP1	RGPD8 RGPD1 RGPD5	2.31e-05	12	90	3	PF00638
Domain	GRIP_dom	RGPD8 RGPD1 RGPD5	2.31e-05	12	90	3	IPR000237
Domain	GRIP	RGPD8 RGPD1 RGPD5	2.31e-05	12	90	3	PS50913
Domain	RANBD1	RGPD8 RGPD1 RGPD5	2.31e-05	12	90	3	PS50196
Domain	RanBD	RGPD8 RGPD1 RGPD5	2.99e-05	13	90	3	SM00160
Domain	Ran_bind_dom	RGPD8 RGPD1 RGPD5	2.99e-05	13	90	3	IPR000156
Domain	LamG	FAT4 CSPG4 TSPEAR CNTNAP4	5.91e-05	44	90	4	SM00282
Domain	Laminin_G	FAT4 CSPG4 TSPEAR CNTNAP4	1.75e-04	58	90	4	IPR001791
Domain	GCC2_Rab_bind	RGPD8 RGPD1	4.75e-04	7	90	2	IPR032023
Domain	Rab_bind	RGPD8 RGPD1	4.75e-04	7	90	2	PF16704
Domain	TPR-contain_dom	CRNKL1 SUGT1 RGPD8 RGPD1 RGPD5	7.94e-04	150	90	5	IPR013026
Domain	LAM_G_DOMAIN	FAT4 CSPG4 CNTNAP4	8.08e-04	38	90	3	PS50025
Domain	TPR-like_helical_dom	CRNKL1 SUGT1 RGPD8 RGPD1 PSMD3 RGPD5	9.19e-04	233	90	6	IPR011990
Domain	TPR_1	SUGT1 RGPD8 RGPD1 RGPD5	9.39e-04	90	90	4	PF00515
Domain	TPR_1	SUGT1 RGPD8 RGPD1 RGPD5	9.39e-04	90	90	4	IPR001440
Domain	Laminin_G_2	FAT4 CSPG4 CNTNAP4	9.40e-04	40	90	3	PF02210
Domain	-	RGPD8 RGPD1	1.01e-03	10	90	2	1.10.220.60
Domain	PH_dom-like	RGPD8 EPB41L4B RGPD1 PHLPP1 NUMB FGD5 SSRP1 RGPD5	1.04e-03	426	90	8	IPR011993
Domain	WWE	HUWE1 ZC3HAV1	1.47e-03	12	90	2	PS50918
Domain	WWE	HUWE1 ZC3HAV1	1.47e-03	12	90	2	PF02825
Domain	WWE-dom	HUWE1 ZC3HAV1	1.47e-03	12	90	2	IPR004170
Domain	Recoverin	HPCA KCNIP1	1.73e-03	13	90	2	IPR028846
Domain	-	RGPD8 EPB41L4B RGPD1 PHLPP1 NUMB FGD5 SSRP1	2.81e-03	391	90	7	2.30.29.30
Domain	-	CRNKL1 SUGT1 RGPD8 RGPD1 PSMD3	3.27e-03	207	90	5	1.25.40.10
Domain	PP2C	PHLPP1 PPM1K	3.72e-03	19	90	2	PF00481
Domain	PP2Cc	PHLPP1 PPM1K	4.12e-03	20	90	2	SM00332
Domain	PPM-type_phosphatase_dom	PHLPP1 PPM1K	4.12e-03	20	90	2	IPR001932
Domain	-	PHLPP1 PPM1K	4.12e-03	20	90	2	3.60.40.10
Domain	PPM_2	PHLPP1 PPM1K	4.12e-03	20	90	2	PS51746
Pathway	REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS	RGPD8 RGPD1 NUP214 NXF1 SYMPK	6.55e-06	50	75	5	MM14610
Pathway	REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA	RGPD8 RGPD1 NUP214 NXF1	7.79e-05	43	75	4	MM14609
Pathway	REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM	RGPD8 RGPD1 NUP214 NXF1 SYMPK	9.27e-05	86	75	5	MM15413
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	SALL1 RGPD8 BRCA2 GLS TET1 RGPD1 ZMYM2 ZFHX3 NUP214 HUWE1 NXF1	1.33e-08	418	91	11	34709266
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	CNBP PHKA2 CRNKL1 SUGT1 RGPD8 SYNE1 RGPD1 TMEM63B ZMYM2 NUP214 CEP76 KIFC3 STAG2 NXF1 RAB8A RGPD5	4.96e-08	1155	91	16	20360068
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	CRNKL1 RGPD8 SYNE1 ZNF638 NUP214 HUWE1 SSRP1 NXF1 ZC3HAV1	2.33e-07	332	91	9	25693804
Pubmed	Complex genomic rearrangements lead to novel primate gene function.	RGPD8 RGPD1 RGPD5	6.02e-07	7	91	3	15710750
Pubmed	Human transcription factor protein interaction networks.	CNBP SALL1 NFIC RGPD1 ZNF638 ZMYM2 PSMD3 REL ZFHX3 RPRD2 NUP214 TFCP2 NXF1 RAB8A SYMPK ZC3HAV1	8.62e-07	1429	91	16	35140242
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	AVEN FAT4 SUGT1 EPB41L4B WASF2 ZNF638 RICTOR ZFHX3 HUWE1 PKHD1L1 CDC42EP3 ZC3HAV1	8.93e-07	777	91	12	35844135
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	CNBP SUGT1 TET1 NUMB RPRD2 HUWE1 SSRP1 SYMPK ZC3HAV1 RGPD5	1.81e-06	549	91	10	38280479
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	SALL1 RGPD8 BRCA2 TET1 RGPD1 ZMYM2	2.45e-06	146	91	6	23892456
Pubmed	TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.	ESYT2 NFIC ZFHX3 SSRP1 TFCP2 NXF1	3.10e-06	152	91	6	28192407
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	FAT4 SUGT1 BRCA2 SYNE1 ZNF638 PSMD3 ROS1 FGD5 NUP214 SSRP1 NXF1	4.54e-06	754	91	11	35906200
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	HPCA RGPD8 SYNE1 RAB8B GLS CSPG4 RGPD1 GRIA2 PSMD3 REL SSRP1 STAG2 PHTF1 RAB8A RGPD5	4.85e-06	1442	91	15	35575683
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ESYT2 NFIC ZNF638 ZMYM2 RICTOR NUP214 HUWE1 SSRP1 STAG2 SYMPK ZC3HAV1	5.81e-06	774	91	11	15302935
Pubmed	The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma.	BACH2 REL	6.77e-06	2	91	2	26522720
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	CNBP FAT4 SALL1 GLS RGPD1 ZMYM2 FGD5 STAG2 TMEM200A RAB8A	6.81e-06	638	91	10	31182584
Pubmed	Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.	RGPD8 RGPD1 NUP214	7.71e-06	15	91	3	14697343
Pubmed	ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.	CLCN6 SYNE1 FA2H BACH2 CSPG4	1.23e-05	113	91	5	34474245
Pubmed	A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.	FRAS1 CSPG4 GRIA2	1.37e-05	18	91	3	14730302
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	CCDC14 AVEN ESYT2 SUGT1 BRCA2 WASF2 BACH2 RGPD1 STIL TFCP2 ZC3HAV1	1.44e-05	853	91	11	28718761
Pubmed	Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.	SV2A RAB8B HUWE1 RAB8A	1.45e-05	56	91	4	27103069
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	PHKA2 ESYT2 SALL1 NFIC WASF2 ZMYM2 REL HUWE1 STAG2 TFCP2 SYMPK	1.50e-05	857	91	11	25609649
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	ESYT2 SUGT1 EPB41L4B ZNF638 ZMYM2 PSMD3 HUWE1	1.90e-05	313	91	7	38270169
Pubmed	Leukemia-Associated Nup214 Fusion Proteins Disturb the XPO1-Mediated Nuclear-Cytoplasmic Transport Pathway and Thereby the NF-κB Signaling Pathway.	NUP214 NXF1	2.03e-05	3	91	2	27114368
Pubmed	Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis.	RAB8B RAB8A	2.03e-05	3	91	2	28076793
Pubmed	Interplay between the phosphatase PHLPP1 and E3 ligase RNF41 stimulates proper kinetochore assembly via the outer-kinetochore protein SGT1.	SUGT1 PHLPP1	2.03e-05	3	91	2	28696259
Pubmed	Rab8 GTPase regulates Klotho-mediated inhibition of cell growth and progression by directly modulating its surface expression in human non-small cell lung cancer.	RAB8B RAB8A	2.03e-05	3	91	2	31707148
Pubmed	RB1 loss overrides PARP inhibitor sensitivity driven by RNASEH2B loss in prostate cancer.	RNASEH2B BRCA2	2.03e-05	3	91	2	35179959
Pubmed	A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport.	RAB8B RAB8A	2.03e-05	3	91	2	12221131
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ESYT2 KCNH8 EPB41L4B NFIC TMEM63B ZNF638 NUMB ZFHX3 RPRD2 HUWE1 PPM1K CDC42EP3 STAG2 ZC3HAV1	3.19e-05	1489	91	14	28611215
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ESYT2 NFIC FA2H ZNF638 ZMYM2 RPRD2 NUP214 SSRP1 STAG2 TFCP2 NXF1 SYMPK ZC3HAV1	3.19e-05	1294	91	13	30804502
Pubmed	Interaction network of human early embryonic transcription factors.	SALL1 NFIC TET1 RGPD1 ZMYM2 ZFHX3 NUP214	3.93e-05	351	91	7	38297188
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	CNBP CRNKL1 SALL1 BRCA2 ZNF638 ZMYM2 RPRD2 NUP214 SSRP1 STAG2 SYMPK	4.00e-05	954	91	11	36373674
Pubmed	The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling.	CSPG4 GRIA2	4.05e-05	4	91	2	12458226
Pubmed	Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1.	RAB8B RAB8A	4.05e-05	4	91	2	26471730
Pubmed	Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis.	RAB8B RAB8A	4.05e-05	4	91	2	24213529
Pubmed	Optineurin mediates a negative regulation of Rab8 by the GTPase-activating protein TBC1D17.	TBC1D17 RAB8A	4.05e-05	4	91	2	22854040
Pubmed	Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.	RGPD8 RGPD5	4.05e-05	4	91	2	9480752
Pubmed	In vitro analysis of nuclear transport mediated by the C-terminal shuttle domain of Tap.	NUP214 NXF1	4.05e-05	4	91	2	11551912
Pubmed	SGT1 regulates Akt signaling by promoting beta-TrCP-dependent PHLPP1 degradation in gastric cancer cells.	SUGT1 PHLPP1	4.05e-05	4	91	2	23440515
Pubmed	Cellular nucleic acid-binding protein is essential for type I interferon-mediated immunity to RNA virus infection.	CNBP REL	4.05e-05	4	91	2	34168080
Pubmed	HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease.	WASF2 RICTOR	4.05e-05	4	91	2	32647003
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	HPCA ESYT2 SUGT1 RGPD8 SV2A GLS RGPD1 GRIA2 PSMD3 RICTOR HUWE1 ADAM22	4.19e-05	1139	91	12	36417873
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	CRNKL1 ESYT2 PSMD3 NUP214 HUWE1 SSRP1 STAG2 SYMPK ZC3HAV1	4.58e-05	638	91	9	33239621
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	SALL1 BACH2 ZNF638 ZMYM2 ZFHX3 SSRP1 PKHD1L1 TFCP2 PHTF1 ZC3HAV1	5.11e-05	808	91	10	20412781
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PHKA2 FRAS1 EPB41L4B WASF2 ZNF638 RICTOR NXF1 TBC1D17 ZC3HAV1	5.28e-05	650	91	9	38777146
Pubmed	The proteasome is involved in determining differential utilization of double-strand break repair pathways.	BRCA2 PSMD3	6.74e-05	5	91	2	17563742
Pubmed	The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.	PKHD1L1 RAB8A	6.74e-05	5	91	2	20048263
Pubmed	The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions.	RAB8B RAB8A	6.74e-05	5	91	2	18094055
Pubmed	Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control.	SUGT1 SSRP1 ZC3HAV1	7.39e-05	31	91	3	25817432
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	ESYT2 RGPD1 ZNF638 ZMYM2 RPRD2 SSRP1	8.11e-05	271	91	6	32433965
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	CCDC14 CNBP SERPINA11 ESYT2 GLS RPRD2 FGD5 TFCP2 SYMPK	8.24e-05	689	91	9	36543142
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	CRNKL1 SYNE1 GLS PSMD3 SCAMP2 FGD5 NUP214 HUWE1 SSRP1 STAG2 TFCP2 NXF1 ZC3HAV1	8.52e-05	1425	91	13	30948266
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CCDC14 ESYT2 SUGT1 ZNF638 PHLPP1 NUMB PSMD3 RICTOR HUWE1 PPM1K SYMPK	9.34e-05	1049	91	11	27880917
Pubmed	The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human.	NUP214 NXF1	1.01e-04	6	91	2	10228171
Pubmed	Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse.	CSPG4 GRIA2	1.01e-04	6	91	2	15601948
Pubmed	Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission.	GRIA2 ADAM22	1.01e-04	6	91	2	16990550
Pubmed	Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.	DENND2A RAB8B RAB8A	1.26e-04	37	91	3	20937701
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	CCDC14 CNBP SUGT1 RPRD2 STIL	1.26e-04	184	91	5	32908313
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ESYT2 FRAS1 SUGT1 SYNE1 GLS NUMB RICTOR SCAMP2 SSRP1 DNAJB9 TFCP2 TBC1D17 ZC3HAV1	1.30e-04	1487	91	13	33957083
Pubmed	Peering through the pore: nuclear pore complex structure, assembly, and function.	RGPD8 RGPD1 NUP214	1.37e-04	38	91	3	12791264
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	CNBP CRNKL1 ESYT2 SYNE1 WASF2 ZMYM2 NUMB RICTOR ZFHX3 SSRP1 STAG2 NXF1 ZC3HAV1	1.39e-04	1497	91	13	31527615
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	CCDC14 CNBP SALL1 SUGT1 SV2A NFIC CSPG4 ZNF638 GRIA2 RICTOR ZNF79 DCT	1.39e-04	1293	91	12	15342556
Pubmed	Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.	RGPD8 RGPD1	1.41e-04	7	91	2	21205196
Pubmed	Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.	RGPD8 RGPD1	1.41e-04	7	91	2	18949001
Pubmed	Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.	RGPD8 RGPD1	1.41e-04	7	91	2	25187515
Pubmed	Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.	RGPD8 RGPD1	1.41e-04	7	91	2	9037092
Pubmed	Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.	RGPD8 RGPD1	1.41e-04	7	91	2	8603673
Pubmed	Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).	RGPD8 RGPD1	1.41e-04	7	91	2	26632511
Pubmed	Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.	RGPD8 RGPD1	1.41e-04	7	91	2	24403063
Pubmed	Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.	RGPD8 RGPD1	1.41e-04	7	91	2	23818861
Pubmed	Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.	RGPD8 RGPD1	1.41e-04	7	91	2	11353387
Pubmed	Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.	RGPD8 RGPD1	1.41e-04	7	91	2	30944974
Pubmed	Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.	RGPD8 RGPD1	1.41e-04	7	91	2	38838144
Pubmed	Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.	RGPD8 RGPD1	1.41e-04	7	91	2	23536549
Pubmed	Retina-specifically expressed novel subtypes of bovine cyclophilin.	RGPD8 RGPD1	1.41e-04	7	91	2	7559465
Pubmed	Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.	RGPD8 RGPD1	1.41e-04	7	91	2	17372272
Pubmed	Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.	RGPD8 RGPD1	1.41e-04	7	91	2	38657106
Pubmed	Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.	RGPD8 RGPD1	1.41e-04	7	91	2	12191015
Pubmed	Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	RGPD8 RGPD1	1.41e-04	7	91	2	22821000
Pubmed	Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.	RGPD8 RGPD1	1.41e-04	7	91	2	20682751
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	CRNKL1 ZMYM2 ZFHX3 SSRP1	1.59e-04	103	91	4	32744500
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	RICTOR RPRD2 NUP214 HUWE1 SSRP1 NXF1 ZC3HAV1	1.61e-04	440	91	7	34244565
Pubmed	Generation and annotation of the DNA sequences of human chromosomes 2 and 4.	TMEM17 IL1F10 RGPD1 ZNF638 PPM1K CDC42EP3 RGPD5	1.65e-04	442	91	7	15815621
Pubmed	The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.	RGPD8 RGPD1	1.88e-04	8	91	2	22262462
Pubmed	The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.	RGPD8 RGPD1	1.88e-04	8	91	2	21670213
Pubmed	TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation.	NUP214 NXF1	1.88e-04	8	91	2	20123736
Pubmed	BRCA2 controls DNA:RNA hybrid level at DSBs by mediating RNase H2 recruitment.	RNASEH2B BRCA2	1.88e-04	8	91	2	30560944
Pubmed	Imaging within single NPCs reveals NXF1's role in mRNA export on the cytoplasmic side of the pore.	NUP214 NXF1	1.88e-04	8	91	2	31375530
Pubmed	Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.	RGPD8 RGPD1	1.88e-04	8	91	2	28745977
Pubmed	Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.	RGPD8 RGPD1	1.88e-04	8	91	2	27412403
Pubmed	Mice lacking Ran binding protein 1 are viable and show male infertility.	RGPD8 RGPD1	1.88e-04	8	91	2	21310149
Pubmed	Functional dissection of Rab GTPases involved in primary cilium formation.	RAB8B TBC1D17 RAB8A	1.98e-04	43	91	3	17646400
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	SALL1 TET1 ZMYM2 SSRP1 SYMPK	2.00e-04	203	91	5	22083510
Pubmed	Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.	RGPD8 RGPD1	2.41e-04	9	91	2	18394993
Pubmed	Sox2 in the dermal papilla regulates hair follicle pigmentation.	DCT CDH3	2.41e-04	9	91	2	35858560
Pubmed	GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR ΔF508.	RAB8B RAB8A	2.41e-04	9	91	2	32344433
Pubmed	The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.	RGPD8 RGPD1	2.41e-04	9	91	2	11553612
Pubmed	The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.	RGPD8 RGPD1	2.41e-04	9	91	2	10601307
Pubmed	The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.	RGPD8 RGPD1	2.41e-04	9	91	2	9733766
Pubmed	Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.	RGPD8 RGPD1	2.41e-04	9	91	2	28100513
Pubmed	Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.	RGPD8 RGPD1	2.41e-04	9	91	2	28877029
Interaction	NXF2 interactions	RGPD8 RICTOR NUP214 NXF1 ZC3HAV1 RGPD5	4.78e-07	65	91	6	int:NXF2
Interaction	RGPD4 interactions	RGPD8 RGPD1 RICTOR RGPD5	2.67e-06	22	91	4	int:RGPD4
Interaction	RGPD1 interactions	RGPD8 RGPD1 RICTOR NXF1 RGPD5	2.74e-06	49	91	5	int:RGPD1
Interaction	RGPD5 interactions	RGPD8 RGPD1 RICTOR HUWE1 NXF1 RGPD5	4.80e-06	96	91	6	int:RGPD5
Interaction	RGPD2 interactions	RGPD8 RGPD1 RICTOR RGPD5	6.30e-06	27	91	4	int:RGPD2
Interaction	S100A6 interactions	CCDC14 SALL1 SUGT1 PHLPP1 RPRD2 NUP214 SYMPK RGPD5	1.05e-05	233	91	8	int:S100A6
Interaction	RGPD6 interactions	CCDC14 HUWE1 STIL NXF1	1.44e-05	33	91	4	int:RGPD6
Interaction	CCDC74A interactions	RGPD8 PSMD3 CEP76 RGPD5	1.83e-05	35	91	4	int:CCDC74A
Interaction	EMD interactions	ESYT2 FRAS1 EVC2 TMEM17 SYNE1 TMEM63B GRIA2 REL ROS1 HUWE1 TMEM200A NXF1 ZC3HAV1	5.26e-05	789	91	13	int:EMD
Interaction	RGPD3 interactions	RGPD8 RGPD1 RICTOR RGPD5	5.98e-05	47	91	4	int:RGPD3
Interaction	NPIPB6 interactions	RGPD8 RGPD1 RGPD5	6.92e-05	18	91	3	int:NPIPB6
Interaction	TMX1 interactions	HGFAC EVC2 TMEM17 GRIA2 ROS1 HUWE1 SEMA4G	9.45e-05	235	91	7	int:TMX1
Interaction	CCDC92 interactions	RGPD8 PSMD3 CEP76 RGPD5	9.62e-05	53	91	4	int:CCDC92
Interaction	RAD51D interactions	BRCA2 REL KIFC3 HUWE1 NXF1	9.91e-05	102	91	5	int:RAD51D
Coexpression	GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_DN	CNBP GIMAP8 WASF2 RNF34 RICTOR NUP214 RAB8A	5.93e-06	200	90	7	M5870
Coexpression	GSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN	NFIC WASF2 PHLPP1 ZFHX3 PPM1K CDC42EP3 STAG2	5.93e-06	200	90	7	M8648
Coexpression	GRESHOCK_CANCER_COPY_NUMBER_UP	CNBP BRCA2 TET1 ZMYM2 REL ROS1 NUP214 STIL	1.57e-05	323	90	8	M9150
Coexpression	GSE360_CTRL_VS_L_DONOVANI_MAC_DN	CNBP ZMYM2 KIFC3 DNAJB9 STAG2 NXF1	6.51e-05	199	90	6	M5159
Coexpression	GSE411_UNSTIM_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN	RNASEH2B PHKA2 REL ROS1 CEP76 CDC42EP3	6.51e-05	199	90	6	M6003
Coexpression	GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP	PHKA2 HGFAC CSPG4 PPM1K CDC42EP3 TFCP2	6.69e-05	200	90	6	M7765
Coexpression	GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN	GIMAP8 BACH2 IFI44 PHLPP1 ZFHX3 STIL	6.69e-05	200	90	6	M7518
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_500	FAT4 SALL1 PCDHB11 CNTNAP4 GRIA2 HUWE1	2.58e-05	137	90	6	gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_1000	FAT4 SALL1 EPB41L4B BACH2 PCDHB11 GRIA2 HUWE1	5.41e-05	229	90	7	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k1
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_200	SALL1 PCDHB11 CNTNAP4 GRIA2	7.54e-05	53	90	4	gudmap_developingLowerUrinaryTract_e14.5_ urethra_200_k2
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNH8 EPB41L4B FA2H GRIA2 CSMD3 DCT TMEM200A	9.96e-08	183	91	7	2cf36ad89584eb9f8b04de52a1b511b7f3527884
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNH8 EPB41L4B FA2H GRIA2 CSMD3 DCT TMEM200A	9.96e-08	183	91	7	98fee6838acfaee5e2e449ba088764ec06b8bc57
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 FRAS1 CNTNAP4 UNC13C ROS1 CSMD3 PKHD1L1	1.03e-07	184	91	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 FRAS1 CNTNAP4 UNC13C ROS1 CSMD3 PKHD1L1	1.03e-07	184	91	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 FRAS1 CNTNAP4 UNC13C ROS1 CSMD3 PKHD1L1	1.03e-07	184	91	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 SALL1 CNTNAP4 OVOS2 FGD5 KCNIP1	1.07e-07	185	91	7	08fad1e3c3cc5f1c3eb6629a49c094b628e75a92
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 SALL1 CNTNAP4 OVOS2 FGD5 KCNIP1	1.33e-07	191	91	7	764c3a8829ae1253a0790744138266e81fc075ec
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CNBP SYNE1 IFI44 ZNF638 RICTOR PPM1K ZC3HAV1	1.70e-07	198	91	7	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HGFAC GIMAP8 TSPEAR FGD5 KCNIP1 PKHD1L1	1.36e-06	170	91	6	6035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HGFAC GIMAP8 TSPEAR FGD5 KCNIP1 PKHD1L1	1.36e-06	170	91	6	c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HGFAC GIMAP8 TSPEAR FGD5 KCNIP1 PKHD1L1	1.36e-06	170	91	6	dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_ACHE\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 KCNH8 SALL1 UNC13C FGD5	1.36e-06	170	91	6	36dbbdb13f69307afd2122ff051b2980850c1f00
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNE1 WASF2 REL CDC42EP3 STAG2 ZC3HAV1	1.78e-06	178	91	6	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CSPG4 TET1 IFI44 NXPE2 CDH3	1.78e-06	178	91	6	6bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 CNTNAP4 OVOS2 FGD5 KCNIP1	2.02e-06	182	91	6	7dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 SALL1 CNTNAP4 FGD5 KCNIP1	2.02e-06	182	91	6	420a8fd30543e37a66ba0786215d056d308660d0
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNH8 EPB41L4B FA2H GRIA2 CSMD3 DCT	2.15e-06	184	91	6	da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 CNTNAP4 OVOS2 FGD5 KCNIP1	2.22e-06	185	91	6	16e9ccea0e3b95d90dc48ef74206c805681dac0b
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 CNTNAP4 OVOS2 FGD5 KCNIP1	2.22e-06	185	91	6	027020754dbf71b0034791f9a34ae795e3b85f81
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 SALL1 CNTNAP4 FGD5 KCNIP1	2.22e-06	185	91	6	cefd81adb480c027545a5c78dcd05669783717f4
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 SALL1 CNTNAP4 FGD5 KCNIP1	2.37e-06	187	91	6	ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HGFAC FAT4 SALL1 CNTNAP4 OVOS2 KCNIP1	3.48e-06	200	91	6	d0167f96314be78b6d867bbcc6e4396071d931b8
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-LBH\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HGFAC FAT4 KCNH8 SALL1 FGD5 SEMA4G	3.48e-06	200	91	6	0ff2607c58bc929e203f407ecf3605e0b21bfa90
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-LBH-L1-2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HGFAC FAT4 KCNH8 SALL1 FGD5 SEMA4G	3.48e-06	200	91	6	de23a5d22d94935802b5b84a9e029b3f62c57028
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DENND2A FAT4 SALL1 KCNIP1 CSMD3	1.67e-05	155	91	5	3b8def9e8f66511736ea37f259511f7c8b7743af
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DENND2A SALL1 TSPEAR KCNIP1 CSMD3	2.00e-05	161	91	5	3b5d7a3dab479c6959a428f3954dedd989900276
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FRAS1 USP29 ROS1 CSMD3 PKHD1L1	2.06e-05	162	91	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-2_VIP_RPL41P3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 KCNH8 FGD5 SEMA4G	2.45e-05	168	91	5	0a7f81266576409560396356d16989e944865844
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-2_VIP_RPL41P3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 KCNH8 FGD5 SEMA4G	2.60e-05	170	91	5	31e3f57673c99f4d8ef30faa9c40e5f7f5bf6460
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-2_VIP_RPL41P3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 SALL1 OVOS2 FGD5	2.67e-05	171	91	5	f6047dee2be0b09ad4d48f97369111bc92e89b35
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	HPCA FAT4 BACH2 TET1 CDH3	3.07e-05	176	91	5	bfa1633e1b7a8a2f04d37fa07284fe9bc0199f46
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HPCA DENND2A SALL1 PCDHB11 CSMD3	3.15e-05	177	91	5	ac90e4ce5be304a5a7473736397327010f2d1999
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	SYNE1 PHLPP1 RICTOR CSMD3 ADAM22	3.15e-05	177	91	5	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 CNTNAP4 OVOS2 FGD5	3.32e-05	179	91	5	97ba67a856680f24846244c0b92c886cc0e79537
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 SALL1 CNTNAP4 OVOS2 KCNIP1	3.41e-05	180	91	5	b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WASF2 BACH2 ZNF638 REL STAG2	3.60e-05	182	91	5	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 CNTNAP4 OVOS2 KCNIP1	3.69e-05	183	91	5	e3ffef2b57dc5b96466dccc9cd54ba326ccf378a
ToppCell	CV-Healthy-7\|CV / Virus stimulation, Condition and Cluster	ESYT2 RGPD8 CLCN6 IFI44 ADAM22	3.79e-05	184	91	5	0e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 SALL1 OVOS2 FGD5	3.89e-05	185	91	5	bdfa8c284bbc5e85c806327fbb7778cf16242a38
ToppCell	CV-Healthy-7\|Healthy / Virus stimulation, Condition and Cluster	RGPD8 CLCN6 GLS IFI44 ADAM22	3.89e-05	185	91	5	1979d189c204f4c2893e3170a514ee7d5523406c
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WASF2 BACH2 ZNF638 REL STAG2	3.89e-05	185	91	5	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SALL1 EPB41L4B FA2H GRIA2 CSMD3	3.99e-05	186	91	5	ea936e66ae4b7b40564711fad60ac0137327995f
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DENND2A GIMAP8 TSPEAR KCNIP1 PKHD1L1	3.99e-05	186	91	5	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KCNH8 EPB41L4B FA2H ROS1 CDH3	4.09e-05	187	91	5	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNH8 SALL1 EPB41L4B GRIA2 CSMD3	4.09e-05	187	91	5	a0bd2b0ec9e73521c245037b1dd51ff8cf24cbf5
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNH8 SALL1 EPB41L4B GRIA2 CSMD3	4.09e-05	187	91	5	f2af79a20438108c814a73f9e24cd986d537237f
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	GLS REL RICTOR HUWE1 ZC3HAV1	4.20e-05	188	91	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ESYT2 FRAS1 GLS ADAM22 ZC3HAV1	4.31e-05	189	91	5	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GIMAP8 TSPEAR FGD5 KCNIP1 PKHD1L1	4.31e-05	189	91	5	55a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC FAT4 SALL1 FGD5 KCNIP1	4.64e-05	192	91	5	3abee376c37c3646da33ac381aa63d50a01607a6
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CSPG4 IFI44 FGD5 NXPE2	4.76e-05	193	91	5	3a5090f81f35026f435f4a250d1e77601a53af15
ToppCell	droplet-Bladder-nan-3m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CSPG4 IFI44 FGD5 NXPE2	4.76e-05	193	91	5	8be24713f8ba2545b7647d1994e9e993623ddaa3
ToppCell	droplet-Bladder-nan-3m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CSPG4 IFI44 FGD5 NXPE2	4.76e-05	193	91	5	19dfc4a2c91fcea4f5991e7c44df46faeecb06b8
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CSPG4 IFI44 FGD5 NXPE2	4.76e-05	193	91	5	13731b7fc1e3bec0cebc44bad7e2ecea358bb76a
ToppCell	droplet-Bladder-nan-3m-Endothelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CSPG4 IFI44 FGD5 NXPE2	4.76e-05	193	91	5	351e0acd411a9eb0dbc0e358d0d1e3759753fa40
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 GIMAP8 SYNE1 FGD5 PKHD1L1	4.76e-05	193	91	5	456aa8a8f1f9cbba0bd618a5f623909079c0f56b
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	DENND2A FAT4 FRAS1 BACH2 UNC13C	4.76e-05	193	91	5	acad568621ed677031797b8c2e34dafea798d681
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DENND2A FAT4 BACH2 UNC13C CSMD3	4.87e-05	194	91	5	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A GIMAP8 TSPEAR FGD5 PKHD1L1	5.12e-05	196	91	5	09a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A GIMAP8 TSPEAR FGD5 PKHD1L1	5.12e-05	196	91	5	e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 GLS GRIA2 CSMD3 ADAM22	5.12e-05	196	91	5	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	HPCA SV2A GRIA2 ZFHX3 PPM1K	5.24e-05	197	91	5	4961f66606f08e399508fd6cabca588e7ab406a8
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 GLS GRIA2 CSMD3 ADAM22	5.37e-05	198	91	5	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 GIMAP8 SYNE1 FGD5 PKHD1L1	5.37e-05	198	91	5	92416e65a0dc1a4bf931833407620ea05d362f56
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 GLS GRIA2 CSMD3 ADAM22	5.37e-05	198	91	5	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 GLS GRIA2 CSMD3 ADAM22	5.37e-05	198	91	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A GIMAP8 TSPEAR KCNIP1 PKHD1L1	5.37e-05	198	91	5	05429f18e1d74880c1835568c86177f661b3477a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 GLS GRIA2 CSMD3 ADAM22	5.37e-05	198	91	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A GIMAP8 TSPEAR KCNIP1 PKHD1L1	5.37e-05	198	91	5	306e28d31fd587409a12dcccc6b2abd7dc9c2e0a
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A GIMAP8 TSPEAR FGD5 PKHD1L1	5.37e-05	198	91	5	b3a020522e064bb61949d38e442f24026e339364
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A GIMAP8 TSPEAR FGD5 PKHD1L1	5.37e-05	198	91	5	fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLS GRIA2 CSMD3 ADAM22 PHTF1	5.37e-05	198	91	5	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 GLS IFI44 RICTOR RGPD5	5.50e-05	199	91	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Fetal_29-31_weeks\|World / Lineage, Cell type, age group and donor	DENND2A FAT4 FRAS1 BACH2 UNC13C	5.50e-05	199	91	5	5b9d355795dd03a22f0961dfd143425c367a4654
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SYNE1 CSPG4 GRIA2 KCNIP1 CSMD3	5.50e-05	199	91	5	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SYNE1 CSPG4 GRIA2 KCNIP1 CSMD3	5.50e-05	199	91	5	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SYNE1 CSPG4 GRIA2 KCNIP1 CSMD3	5.50e-05	199	91	5	e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC14 SYNE1 GLS ROS1 PLA2G4F	5.50e-05	199	91	5	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-BAGE2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FAT4 SALL1 CNTNAP4 OVOS2 KCNIP1	5.63e-05	200	91	5	26f07d271e984f375145e4c10528fba44a5811e1
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DENND2A SYNE1 CSPG4 ZFHX3 ADAM22	5.63e-05	200	91	5	f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-BAGE2-L1-2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FAT4 SALL1 CNTNAP4 OVOS2 KCNIP1	5.63e-05	200	91	5	c3637827ceba16b0d7956c280dd2ddbc8b1ba55e
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HGFAC IFI44 OVOS2 FGD5 KCNIP1	5.63e-05	200	91	5	8a8f9d9e5ffab3f736c4bd0a5bb616d442d137d1
ToppCell	Neuronal-Inhibitory-iA\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HGFAC FAT4 SALL1 CNTNAP4 KCNIP1	5.63e-05	200	91	5	5ef4a3dc18a44292184a59ced916183c0699b01e
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CCDC184-L1-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HGFAC FAT4 KCNH8 SALL1 FGD5	5.63e-05	200	91	5	140aff451cd58e1d544ee668e49e37e577f6f068
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CCDC184\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HGFAC FAT4 KCNH8 SALL1 FGD5	5.63e-05	200	91	5	85bfa7f4dd07a4d4a88330e88f5886fd1ecfdeeb
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HGFAC FAT4 SALL1 FGD5 KCNIP1	5.63e-05	200	91	5	75649534a98bc738fca62d071de0978dc61eb24f
ToppCell	COVID-19-kidney-Mito-rich_Int\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IL1F10 CNTNAP4 UNC13C CSMD3	1.15e-04	122	91	4	a4220adb4e6055a599bd9bbf65d460fc4e68b543
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KCNH8 FA2H CSPG4 DCT	1.60e-04	133	91	4	63d2f096ae47d9b587acc6c5fbd346e5e58842b8
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KCNH8 FA2H CSPG4 DCT	1.89e-04	139	91	4	a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCell	367C-Lymphocytic-ILC-ILC-2\|ILC / Donor, Lineage, Cell class and subclass (all cells)	RNASEH2B SCAMP2 RAB8A	1.95e-04	55	91	3	7916216b3a24f9c6b966aa5392fc2bc43b3d2c4c
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DENND2A SALL1 TSPEAR KCNIP1	2.17e-04	144	91	4	0322fef818a963be00535d5f141f028d43de5c6a
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DENND2A FAT4 SALL1 CSMD3	2.17e-04	144	91	4	7de962346ba9653d90dd13bb7d977fe44d200bba
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 USP29 ROS1 CSMD3	2.23e-04	145	91	4	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	HGFAC DENND2A SALL1 KCNIP1	2.28e-04	146	91	4	47368f981180ca6a8c81a50f7f9430f12456f609
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DENND2A SALL1 FGD5 KCNIP1	2.47e-04	149	91	4	98ae408d2d0347865875ff8bbd89d359decea526
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FAT4 EPB41L4B CSMD3 CDH3	2.47e-04	149	91	4	c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FAT4 EPB41L4B CSMD3 CDH3	2.47e-04	149	91	4	a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175\|Adult / Lineage, Cell type, age group and donor	UNC13C ROS1 CSMD3 RGPD5	2.53e-04	150	91	4	b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTNAP4 GRIA2 UNC13C CSMD3	2.53e-04	150	91	4	0205318a870e091add66ee4305747dda9f51510d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SV2A CSPG4 GRIA2 ZFHX3	2.66e-04	152	91	4	0cb5f4dfae04e3f4eba502bbf229007d5fa3884d
Drug	F-Fb	SALL1 RNF34 ROS1	3.41e-06	8	91	3	CID000445770
Disease	Dyggve-Melchior-Clausen disease (implicated_via_orthology)	RAB8B RAB8A	5.02e-05	4	86	2	DOID:0111167 (implicated_via_orthology)
Disease	Smith-McCort dysplasia (implicated_via_orthology)	RAB8B RAB8A	8.35e-05	5	86	2	DOID:0060247 (implicated_via_orthology)
Disease	platelet crit	HGFAC DENND2A IL1F10 NFIC BACH2 PHLPP1 NUMB RICTOR RPRD2 CDH3 ZC3HAV1	1.00e-04	952	86	11	EFO_0007985
Disease	pneumococcal meningitis	PCDHB11 ROS1	2.32e-04	8	86	2	EFO_1001114
Disease	Malignant tumor of prostate	BRCA2 ZFHX3	2.98e-04	9	86	2	cv:C0376358
Disease	multiple sclerosis symptom measurement	TMEM17 USP29 UNC13C	3.31e-04	46	86	3	EFO_0803536
Disease	3-methyl-2-oxobutyrate measurement	FAT4 PPM1K	3.72e-04	10	86	2	EFO_0021020
Disease	lymphangioleiomyomatosis (is_marker_for)	GLS RICTOR	5.44e-04	12	86	2	DOID:3319 (is_marker_for)
Disease	melanoma	FAT4 BRCA2 ROS1 MAGEC1 STAG2	8.06e-04	248	86	5	C0025202
Disease	hepatoblastoma (is_marker_for)	SALL1 ZFHX3	8.60e-04	15	86	2	DOID:687 (is_marker_for)
Disease	Carcinoma of lung	BRCA2 RICTOR	2.04e-03	23	86	2	C0684249
Disease	Glioma	BRCA2 ROS1 STAG2	2.12e-03	87	86	3	C0017638
Disease	heart failure	AVEN ZNF638 ZFHX3 SYMPK	2.13e-03	185	86	4	EFO_0003144
Disease	Neoplasm of the genitourinary tract	BRCA2 ZFHX3	2.22e-03	24	86	2	cv:C0042065
Disease	colorectal adenocarcinoma (is_marker_for)	HPCA RICTOR	2.81e-03	27	86	2	DOID:0050861 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
FASSSQRRSAFGFDD	ESYT2	26	A0FGR8
SGFASTFREDNSSNS	BACH2	251	Q9BYV9
TSGNGFNFNDVVTFS	CSMD3	2886	Q7Z407
DQGEVVFAFTNFSSS	CSPG4	2006	Q6UVK1
STVTSNIRVFFAGFS	FAT4	3691	Q6V0I7
VDQASFQVDAFGTSF	ADAM22	86	Q9P0K1
FSGEEEVSATFQFRT	CNTNAP4	386	Q9C0A0
FERTTSISAGNEEFQ	CEP76	566	Q8TAP6
HNEFFRANSTSDSVF	CDC42EP3	81	Q9UKI2
SFSTFTSRDEQDFRN	CCDC14	916	Q49A88
RGSGSSFEQSFNFNF	DNAJB9	101	Q9UBS3
EINFSFSRSFASSGR	PPM1K	356	Q8N3J5
FRFSEDAFNSTFIST	RAB8A	26	P61006
FRFSEDAFNTTFIST	RAB8B	26	Q92930
IFGQTSSTFTFADVA	RGPD5	961	Q99666
LFRFDESTTGSNFSF	RGPD5	1281	Q99666
IFGQTSSTFTFADVA	RGPD8	961	O14715
LFRFDESTTGSNFSF	RGPD8	1281	O14715
TFDTNSDGTIDFREF	HPCA	71	P84074
VGFSNATFQSERESG	GLS	371	O94925
QNTVTFSSEGSSEIF	OVOS1	1046	Q6IE37
ATRFTFFQSSSGSAF	IL1F10	96	Q8WWZ1
FFQSSSGSAFRLEAA	IL1F10	101	Q8WWZ1
DSFRFEVSSASNAQT	FRAS1	1431	Q86XX4
SFSERTQSTFEGFAQ	MAGEC1	251	O60732
RETQSSESTNEFGIF	GRIA2	581	P42262
EDSFTRFSSQSNVYG	KPTN	16	Q9Y664
NTRAQFFVEDASTAS	NXF1	156	Q9UBU9
RFSGSAFSSVFQSIN	FGD5	1326	Q6ZNL6
DSVGNRTSEGFQAFS	EVC2	216	Q86UK5
VFGQSASSAASVFSF	NUP214	1731	P35658
NTVTFSSEGSSEIQF	OVOS2	1251	Q6IE36
FGRADSFTFSVEQSN	OVOS2	1391	Q6IE36
FTSRFTSAQSFNFTR	PLA2G4F	626	Q68DD2
FFNRTTDVTQTFGIE	HGFAC	466	Q04756
RQSSDFDTQSGFSIN	HUWE1	1996	Q7Z6Z7
FDTQSGFSINSQVFA	HUWE1	2001	Q7Z6Z7
RFGSSSTSTFFLDIN	RICTOR	1051	Q6R327
FNAFDTTQTGSVKFE	KCNIP1	106	Q9NZI2
KNSEENSTFRNSFGF	PCDHB11	781	Q9Y5F2
FAQGNVRLFTSFTTE	FA2H	191	Q7L5A8
GFIQTASRRQTFFDS	DYRK4	326	Q9NR20
SATFTLNFFRSGIQF	CLCN6	286	P51797
FSESFVVSVSSQSRF	CRNKL1	131	Q9BZJ0
SFFNSVRSVFQGHVT	IFI44	201	Q8TCB0
FETSDTFFQTASGKN	BRCA2	1421	P51587
QQFTSETFSFVLTGE	DENND2A	626	Q9ULE3
SSAGDSFSQFRFAEE	AVEN	146	Q9NQS1
SVSSSVDFDQRDNGF	TMEM63B	111	Q5T3F8
GFSEQSVTQSFLSES	GIMAP8	276	Q8ND71
ESVGSFRSNSFNSTF	RPRD2	1176	Q5VT52
ASSENGTNFRFTRFV	SALL1	1301	Q9NSC2
TFTTGPQFTADFRDS	EPB41L4B	821	Q9H329
FSTDNDDFTVRNGET	CDH3	66	P22223
TRRFSADEQFFSVGQ	PHKA2	1011	P46019
ADEQFFSVGQAASSS	PHKA2	1016	P46019
IFGQTSSTFTFADVA	RGPD1	946	P0DJD0
IFRFDESTTGFNFSF	RGPD1	1266	P0DJD0
TFDASRTTFTREGSF	NUMB	181	P49757
EAQSFAQFVTTGESA	SYNE1	1506	Q8NF91
AANTIASFSGFRSSF	TMEM200A	206	Q86VY9
FTGLFANRSSNVFTE	NXPE2	216	Q96DL1
FEFGHTNRTTEFTNL	KIFC3	626	Q9BVG8
QEEFSQGIFSSRTFH	SCAMP2	301	O15127
FQESFVTSGVFSVTE	NFIC	216	P08651
FEDVTSSNTFFRNCT	SV2A	536	Q7L0J3
FVNFARGTTTTRSFD	SSRP1	376	Q08945
GTSEFSTVDSAQKNF	TET1	1381	Q8NFU7
GFTSDRGFQFVSSSL	CNBP	36	P62633
LGNFSRAVFSDSNRT	TMEM17	11	Q86X19
SSVQERVFSESGNFI	STIL	286	Q15468
STTFSSFSRVTNFFR	TBC1D17	221	Q9HA65
AVQGFFTSNNATRDF	PSMD3	116	O43242
FFTERATEEGSGSFT	SEMA4G	241	Q9NTN9
SEDFSENQFFTRTNG	UNC13C	561	Q8NB66
EFESAAFSQGSRSGV	PHTF1	341	Q9UMS5
SSRVQSTAFFSGDQA	RNASEH2B	186	Q5TBB1
RFSTFTRLFTNFSGA	TFCP2	341	Q12800
SSRSQTSSFFTRSFF	RNF34	166	Q969K3
FSANFTDSVTTGRQI	SERPINA11	166	Q86U17
IQENGYNFDRSSSTF	STAG2	931	Q8N3U4
FTTAELGTSNSSANF	GTF2A1L	96	Q9UNN4
VEFNFDSVTESTNGF	USP29	701	Q9HBJ7
VQESSFRIEGNASSF	ROS1	951	P08922
NTTVFVSQSDAFEGS	REL	551	Q04864
TTLTISGRFFDQTDF	PKHD1L1	286	Q86WI1
AGTATSQRFFQSFSD	SUGT1	6	Q9Y2Z0
QNSTFSFRNALEGFD	DCT	341	P40126
GDSVTRRSVASQFFT	SYMPK	6	Q92797
FGELFTQANTFASRV	WASF2	51	Q9Y6W5
TKNRTNDVDFSTSSF	ZMYM2	146	Q9UBW7
SFQRQLSSATFSSAF	PHLPP1	1526	O60346
ASSTTYRNSEGQFFS	ZBTB49	731	Q6ZSB9
VVANSFDGRTFSVNS	TSPEAR	601	Q8WU66
DRFFQGSQEFLASAS	ZC3HAV1	251	Q7Z2W4
GSTFFSSVTVAFAQE	ZNF79	36	Q15937
GESSNNRSFFSVESG	ZNF638	276	Q14966
SSNSASSFVVFDGAN	ZFHX3	551	Q15911
NSSEESQTFDFGSER	KCNH8	821	Q96L42