Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoPurkinje cell axonal dystrophy

GNPTAB HERC2

7.98e-062402MP:0013159
MousePhenodecreased susceptibility to colitis induced morbidity/mortality

GPR35 TPSG1

4.77e-054402MP:0013299
MousePhenoincreased lysosomal enzyme secretion

GNPTAB HPS1

7.94e-055402MP:0003174
MousePhenoabnormal susceptibility to induced colitis

NLRP12 ABCC4 GPR35 TPSG1 NLRP3

9.05e-05161405MP:0013296
MousePhenodecreased susceptibility to induced colitis

GPR35 TPSG1 NLRP3

1.71e-0438403MP:0008539
DomainNACHT-assoc

NLRP12 NLRP3

6.47e-062482IPR029495
DomainFISNA

NLRP12 NLRP3

6.47e-062482PF14484
DomainFISNA

NLRP12 NLRP3

6.47e-062482SM01288
Domain-

GTF2IRD2B GTF2IRD2

3.87e-0544823.90.1460.10
DomainGTF2I

GTF2IRD2B GTF2IRD2

3.87e-054482PS51139
DomainGTF2I

GTF2IRD2B GTF2IRD2

3.87e-054482PF02946
DomainGTF2I

GTF2IRD2B GTF2IRD2

3.87e-054482IPR004212
DomainAPC_su10/DOC_dom

HERC2 ZZEF1

1.35e-047482IPR004939
DomainDOC

HERC2 ZZEF1

1.35e-047482PS51284
DomainAPC10

HERC2 ZZEF1

1.35e-047482SM01337
DomainANAPC10

HERC2 ZZEF1

1.35e-047482PF03256
DomainZZ

HERC2 ZZEF1

9.64e-0418482PF00569
DomainZF_ZZ_2

HERC2 ZZEF1

9.64e-0418482PS50135
DomainZF_ZZ_1

HERC2 ZZEF1

9.64e-0418482PS01357
DomainZnf_ZZ

HERC2 ZZEF1

1.08e-0319482IPR000433
DomainZnF_ZZ

HERC2 ZZEF1

1.08e-0319482SM00291
DomainDAPIN

NLRP12 NLRP3

1.45e-0322482PS50824
DomainPYRIN

NLRP12 NLRP3

1.45e-0322482PF02758
DomainDAPIN

NLRP12 NLRP3

1.45e-0322482IPR004020
DomainPYRIN

NLRP12 NLRP3

1.45e-0322482SM01289
DomainNACHT

NLRP12 NLRP3

1.58e-0323482PS50837
DomainNACHT_NTPase

NLRP12 NLRP3

1.58e-0323482IPR007111
Domain-

ASB17 ASB16 YTHDC2 FEM1C

3.73e-032484841.25.40.20
DomainANK

ASB17 ASB16 YTHDC2 FEM1C

3.90e-03251484SM00248
DomainANK_REPEAT

ASB17 ASB16 YTHDC2 FEM1C

4.01e-03253484PS50088
DomainAnkyrin_rpt-contain_dom

ASB17 ASB16 YTHDC2 FEM1C

4.07e-03254484IPR020683
DomainANK_REP_REGION

ASB17 ASB16 YTHDC2 FEM1C

4.07e-03254484PS50297
DomainSOCS_box

ASB17 ASB16

4.29e-0338482PF07525
DomainSOCS_box

ASB17 ASB16

4.51e-0339482SM00969
DomainSOCS

ASB17 ASB16

4.51e-0339482PS50225
DomainSOCS_box

ASB17 ASB16

4.51e-0339482IPR001496
DomainAnkyrin_rpt

ASB17 ASB16 YTHDC2 FEM1C

4.54e-03262484IPR002110
DomainLeu-rich_rpt

NLRP12 LRRC10 RTN4RL1 NLRP3

5.11e-03271484IPR001611
DomainLRR_6

NLRP12 NLRP3

8.81e-0355482PF13516
Domain-

NLRP12 LRRC10 RTN4RL1 NLRP3

9.20e-033214843.80.10.10
DomainL_dom-like

NLRP12 LRRC10 RTN4RL1 NLRP3

9.90e-03328484IPR032675
DomainARM-type_fold

RELCH PI4KA ULK4 KPNA6

1.11e-02339484IPR016024
DomainKinase-like_dom

TRIO TRPM7 PI4KA DYRK1A ULK4

1.24e-02542485IPR011009
Pubmed

Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.

ASB17 RBL1 ASB16 FEM1C PDZRN3 RNF26

4.25e-0813849628786561
Pubmed

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.

ULK4 HERC2 DNAH11

1.76e-061749323502783
Pubmed

Rare mutations in NLRP3 and NLRP12 associated with familial cold autoinflammatory syndrome: two Chinese pedigrees.

NLRP12 NLRP3

1.94e-06249235852776
Pubmed

NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome.

NLRP12 NLRP3

1.94e-06249238261657
Pubmed

Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.

GTF2IRD2B GTF2IRD2

1.94e-06249215388857
Pubmed

Regulation of Dyrk1A kinase activity by 14-3-3.

DYRK1A YWHAE

1.94e-06249215369779
Pubmed

Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity.

NLRP12 NLRP3

1.94e-06249220861349
Pubmed

Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.

GTF2IRD2B GTF2IRD2

5.83e-06349215100712
Pubmed

NLRP12 c.1382dup promotes the development of Crohn's disease through the ERK/NLRP3/ IL-1β pathway.

NLRP12 NLRP3

5.83e-06349239181275
Pubmed

Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk.

ULK4 DNAH11

5.83e-06349222120009
Pubmed

Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms.

GSDME NLRP3

5.83e-06349237913775
Pubmed

Association of EGF Receptor and NLRs signaling with Cardiac Inflammation and Fibrosis in Mice Exposed to Fine Particulate Matter.

NLRP12 NLRP3

1.16e-05449227158778
Pubmed

TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.

GTF2IRD2B GTF2IRD2

1.16e-05449217823943
Pubmed

Evolution of general transcription factors.

GTF2IRD2B GTF2IRD2

1.16e-05449223229069
Pubmed

GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.

GTF2IRD2B GTF2IRD2

1.16e-05449222899722
Pubmed

NLRP3, NLRP12, and IFI16 Inflammasomes Induction and Caspase-1 Activation Triggered by Virulent HSV-1 Strains Are Associated With Severe Corneal Inflammatory Herpetic Disease.

NLRP12 NLRP3

1.16e-05449231367214
Pubmed

Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.

GTF2IRD2B GTF2IRD2

1.16e-05449221328569
Pubmed

An integrated deletion and physical map encompassing l71Rl, a chromosome 7 locus required for peri-implantation survival in the mouse.

GAS2 HERC2

1.94e-05549210903848
Pubmed

NLRP3 selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severity.

GSDME NLRP3

1.94e-05549237730693
Pubmed

Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment.

NLRP12 NLRP3

1.94e-05549227779193
Pubmed

Fas-associated factor 1 is a negative regulator of PYRIN-containing Apaf-1-like protein 1.

NLRP12 NLRP3

1.94e-05549217046979
Pubmed

Evaluation of Nod-like receptor (NLR) effector domain interactions.

NLRP12 NLRP3

2.91e-05649219337385
Pubmed

NLRC4 suppresses melanoma tumor progression independently of inflammasome activation.

NLRP12 NLRP3

2.91e-05649227617861
Pubmed

Polymorphisms in NACHT-LRR (NLR) genes in atopic dermatitis.

NLRP12 NLRP3

4.07e-05749217620097
Pubmed

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.

NLRP12 NLRP3

4.07e-05749219158675
Pubmed

Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition.

GSDME NLRP3

4.07e-05749233308446
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TRIO TRPM7 GNPTAB DYRK1A FUZ KPNA6 HERC2 YWHAE ZNF292

6.76e-05128549935914814
Pubmed

A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling.

GSDME NLRP3

6.96e-05949232268091
Pubmed

Genomic analysis of orthologous mouse and human olfactory receptor loci.

OR2AG2 OR2AG1

6.96e-05949211416212
Pubmed

Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.

NLRP12 NLRP3

6.96e-05949224799678
Pubmed

Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.

NLRP12 NLRP3

6.96e-05949224453977
Pubmed

A microsatellite map of the pink-eyed dilution (p) deletion complex in mouse chromosome 7.

GAS2 HERC2

8.69e-05104929060416
Pubmed

Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock.

NLRP12 NLRP3

1.06e-041149226572062
Pubmed

NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis.

NLRP12 NLRP3

1.27e-041249221565393
Pubmed

Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.

GSDME NLRP3

1.50e-041349232763970
Pubmed

SGK2, 14-3-3, and HUWE1 Cooperate to Control the Localization, Stability, and Function of the Oncoprotein PTOV1.

DYRK1A YWHAE

1.50e-041349234654719
Pubmed

Complementation analyses for 45 mutations encompassing the pink-eyed dilution (p) locus of the mouse.

GAS2 HERC2

1.50e-04134928601493
Pubmed

The NLRP12 inflammasome recognizes Yersinia pestis.

NLRP12 NLRP3

1.75e-041449222840842
Pubmed

The genetics of NOD-like receptors in Crohn's disease.

NLRP12 NLRP3

1.75e-041449220403135
Pubmed

NALPs: a novel protein family involved in inflammation.

NLRP12 NLRP3

1.75e-041449212563287
Pubmed

The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation.

GSDME NLRP3

2.02e-041549230485804
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

TRIO POLRMT HERC2 ZZEF1

2.29e-0421249433853758
Pubmed

Molecular analysis of 36 mutations at the mouse pink-eyed dilution (p) locus.

GAS2 HERC2

2.30e-04164928601494
Pubmed

ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes.

ASB17 ASB16

2.61e-041749216325183
Pubmed

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.

NLRP12 NLRP3

2.61e-041749222297845
Pubmed

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.

TRIO PI4KA COBLL1 GAS2

3.13e-0423049435449600
Pubmed

Impact of ancestry and common genetic variants on QT interval in African Americans.

TRPM7 PDZRN3

3.27e-041949223166209
Pubmed

Transcriptional fates of human-specific segmental duplications in brain.

GTF2IRD2B GTF2IRD2

3.27e-041949230228200
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

POLRMT DYRK1A YTHDC2 KPNA6 HERC2

3.82e-0444049534244565
Pubmed

Epithelial-derived gasdermin D mediates nonlytic IL-1β release during experimental colitis.

YWHAE NLRP3

4.83e-042349232597834
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

TRIO PI4KA YTHDC2 HERC2 YWHAE

5.41e-0447549531040226
Pubmed

Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.

GSDME NLRP3

5.71e-042549235139355
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

TRIO HERC2 YWHAE

6.57e-0412049331413325
Pubmed

Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy.

ABCC4 GSTO2

8.25e-043049220200426
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TRIO PI4KA POLRMT DYRK1A ULK4 HERC2 ZZEF1

8.59e-04110549735748872
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

TRPM7 RBL1 KPNA6 HERC2 ZZEF1

9.08e-0453349525544563
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

RBL1 POLRMT YTHDC2 KPNA6 ZZEF1 YWHAE PDZRN3

9.10e-04111649731753913
Pubmed

Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes.

GAS2 PDZRN3

9.39e-043249221546767
Pubmed

Mettl14-mediated m6A modification ensures the cell-cycle progression of late-born retinal progenitor cells.

YTHDC2 ZNF292

1.12e-033549237269288
Pubmed

A probabilistic classifier for olfactory receptor pseudogenes.

OR52A4P OR2AG1

1.12e-033549216939646
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

RBL1 PI4KA POLRMT DYRK1A ZBTB40 KPNA6

1.25e-0385749625609649
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

TRIO GNPTAB YWHAE

1.28e-0315149317043677
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TRIO TRPM7 PI4KA COBLL1 DYRK1A YWHAE

1.28e-0386149636931259
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

HERC2 ZZEF1

4.56e-041832291
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

NLRP12 NLRP3

8.88e-0425322994
GeneFamilyNLR family

NLRP12 NLRP3

8.88e-0425322666
GeneFamilyAnkyrin repeat domain containing

ASB17 ASB16 FEM1C

8.82e-03242323403
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

ABCC4 TRPM7 GNPTAB ZBTB40 ITGAD ZNF292

5.55e-081864968571956890fc9894d766ba294a28e376b4aba428
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-mast_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCC4 TRIO COBLL1 GNPTAB TPSG1

1.83e-061854953fafb1d36c5f98a29d20a5ce5192c83d6f603514
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

ABCC4 TRPM7 GNPTAB ZBTB40 ZNF292

1.83e-06185495a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

ABCC4 TRPM7 GNPTAB ZBTB40 ZNF292

2.14e-061914959454f642c3621370fa23640b631301346b300950
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NLRP12 GSDME CCDC180 NLRP3

2.68e-05157494320d5ac063fd90e26f537475c328b3ae73974bc1
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid-mast_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NLRP12 GSDME CCDC180 NLRP3

2.68e-05157494e4b17c267b754c5af95cdf17f629354d1a8a8ad7
ToppCelldroplet-Lung-LUNG-1m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NLRP12 GSDME CCDC180 NLRP3

2.74e-0515849430cceb73cf5e24b692da84d33342fd3b1ad5efe5
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NLRP12 GSDME CCDC180 NLRP3

2.74e-0515849447793463640f98ee5f680a1ee5786b453355fd57
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid-cardiac_mast_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NLRP12 GSDME CCDC180 NLRP3

2.81e-05159494766dfb9f9c0783e740a4fd395e99669310b33371
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELCH COBLL1 GAS2 RTN4RL1

2.88e-0516049455f599df6e3b7a5a505df4b094c834281311d94a
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NLRP12 GPR35 FPR3 NLRP3

2.88e-051604946ed37d1fd0304932319d6b942502404115ff36a7
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELCH COBLL1 GAS2 RTN4RL1

2.88e-05160494296e53e1e0786346d38db2d4188b9a1c0430627b
ToppCelldroplet-Lung-21m-Hematologic-myeloid-neutrophil|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NLRP12 GSDME CCDC180 NLRP3

3.02e-05162494f24eb596653180040bfdefad9c246fc42cbfaac8
ToppCelldroplet-Lung-21m-Hematologic-myeloid-neutrophil-neutrophil|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NLRP12 GSDME CCDC180 NLRP3

3.02e-051624941a953e165b7e469815294728350ec13d27c9bd9d
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 RTN4RL1 ULK4 ITGAD

4.00e-05174494f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellASK440-Immune-Mast_cell|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

ABCC4 GPR35 GNPTAB TPSG1

4.37e-05178494dcefc4afca3a40d1bd44722e66bca6b45a6c6c55
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCC4 TRIO COBLL1 TPSG1

5.18e-05186494de55471dd5c842026b409cfebf67fe32f079a011
ToppCellBAL-Control-Myeloid-MoAM-MoAM1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GSDME GPR35 FPR3 ITGAD

5.51e-05189494ebb5e069fdca7cf8ffac16a57572e92d2593c86a
ToppCellControl-Myeloid-MoAM1|Control / Disease group,lineage and cell class （2021.01.30）

GSDME GPR35 FPR3 ITGAD

5.51e-0518949455d5c2fb9e6ab556d42c83a1e985ee66e4cf9dba
ToppCellASK440-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

ABCC4 GPR35 GNPTAB TPSG1

5.51e-0518949472a19b20cb0f7283afe5f85d62a21cff69fd78d0
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GDPD4 ABCC4 GPR35 TPSG1

5.51e-05189494aba941ba6ce7702418b3f470bde573d123c4aade
ToppCellBAL-Control-Myeloid-MoAM-MoAM1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GSDME GPR35 FPR3 ITGAD

5.51e-05189494a59e4eaff430a443f9fa7edabe64e66a15b6bffb
ToppCellBAL-Control-Myeloid-MoAM-MoAM1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GSDME GPR35 FPR3 ITGAD

5.63e-051904944b4fe93061c87605dddf5bec94fa07c749c722aa
ToppCellBAL-Control-Myeloid-MoAM-MoAM1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GSDME GPR35 FPR3 ITGAD

5.63e-051904945c8aa310886c64ee5dce4ba46a3dd178da549529
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GDPD4 ABCC4 GPR35 TPSG1

5.86e-05192494690cf19e9b0b2ada80097c63eae827529aa5b6f3
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GDPD4 ABCC4 GPR35 TPSG1

5.86e-051924943d6c4c5847ca1e44fa380403d25af45d5b51ee9b
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GDPD4 ABCC4 GPR35 TPSG1

5.86e-05192494e0412964a3ee1bf3c0ef64f9a6f20f7e7835701e
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GDPD4 ABCC4 GPR35 TPSG1

5.86e-05192494b5871247a5f3e970fa05b33fff21bef9d2ab5741
ToppCellControl-Myeloid-MoAM5,_CCL3L1|Control / Condition, Lineage and Cell class

GSDME GPR35 FPR3 NLRP3

6.10e-05194494a1dd264822de83a0ffaf89ca4707c6a76809359e
ToppCellBAL-Control-Myeloid-MoAM|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GSDME GPR35 FPR3 NLRP3

6.10e-05194494125bf2909cf89133693bc7b865ca08955cf67a2e
ToppCellControl-Myeloid-MoAM5,_CCL3L1|Myeloid / Condition, Lineage and Cell class

GSDME GPR35 FPR3 NLRP3

6.10e-0519449496400477d130b2403ed81c229e4e4182cc2cdc14
ToppCellBAL-Control-Myeloid-MoAM|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

GSDME GPR35 FPR3 NLRP3

6.10e-05194494a4523adbbd25c314809eed3414d66a5b323446e5
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell|GW09 / Sample Type, Dataset, Time_group, and Cell type.

AGPAT5 TRIO GTF2IRD2 POLRMT

6.35e-051964947be50b9156394dea44d7b8b476d4dd516abfafae
ToppCellControl_saline-Hematopoietic_Myeloid|Control_saline / Treatment groups by lineage, cell group, cell type

NLRP12 GPR35 FPR3 NLRP3

6.73e-051994946be92062cce049a4c98f7311f2500bf1468fc267
ToppCellBronchial-10x5prime-Immune_Myeloid-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC4 GPR35 GNPTAB TPSG1

6.86e-0520049496540be0e906bbc626049a41978be3dc051d2024
ToppCellBronchial-10x5prime-Immune_Myeloid-Mast_cell-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC4 GPR35 GNPTAB TPSG1

6.86e-0520049441d7736427494cb30a2f23722ea2b86ff308cfd8
ToppCellBiopsy_IPF-Immune-Mast_cells|Biopsy_IPF / Sample group, Lineage and Cell type

ABCC4 GPR35 GNPTAB TPSG1

6.86e-0520049444d07a3fa768ccdcd2a0483a41483d5c11c9111e
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2|Hippocampus / BrainAtlas - Mouse McCarroll V32

GDPD4 NLRP12 SLC34A1

9.06e-057949303c5af851b53800eced1c74e9da374c71092bcd4
DiseaseFamilial cold autoinflammatory syndrome

NLRP12 NLRP3

1.55e-054482cv:C0343068
DiseaseAL amyloidosis

ULK4 DNAH11

1.69e-0412482MONDO_0019438
Diseasemultiple myeloma, monoclonal gammopathy

ULK4 DNAH11

2.33e-0414482EFO_0000203, EFO_0001378
Diseasemonocyte measurement

NLRP12 GPR35 DYRK1A

3.27e-0482483EFO_0803547
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

TRIO ZNF292

3.47e-0417482DOID:0060307 (is_implicated_in)
DiseaseNeurodevelopmental Disorders

TRIO DYRK1A ZNF292

4.73e-0493483C1535926
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

AGPAT5 COBLL1 DNAH11

5.68e-0499483EFO_0004611, EFO_0007878
DiseaseC-reactive protein measurement

COBLL1 DYRK1A ZBTB40 RTN4RL1 YTHDC2 ZZEF1 NLRP3 DNAH11

6.70e-041206488EFO_0004458
Diseaselymphocyte percentage of leukocytes

GTF2IRD2B RBL1 GTF2IRD2 YWHAE NLRP3 ZNF292

7.03e-04665486EFO_0007993
Diseasemultiple myeloma

ULK4 HERC2 DNAH11

8.13e-04112483EFO_0001378
Diseaseessential tremor

TRIO DHRS13 YWHAE

1.42e-03136483EFO_0003108
DiseaseAutoinflammatory disorder

NLRP12 NLRP3

1.49e-0335482C3860213

Protein segments in the cluster

PeptideGeneStartEntry
ICCDILDVLDKHLIP

YWHAE

96

P62258
ELHCIILSLPPCLKI

APOBEC1

181

P41238
TCCKLQIIPTLCHLL

GSDME

406

O60443
LLKLPLRCHECQQLL

APTX

326

Q7Z2E3
HLCTIPESLQCAKLL

ASB16

181

Q96NS5
LVQTLCVLLECLLTP

DNAH11

2376

Q96DT5
LSIIHCDLKPENILL

DYRK1A

281

Q13627
RLKHLCTICDLLPPS

CCDC180

396

Q9P1Z9
ICSKCEFDPLHTLLL

COBLL1

176

Q53SF7
CCVELLLLLVAAELP

RTN4RL1

6

Q86UN2
LKCALCHKVLEDPLT

PDZRN3

16

Q9UPQ7
ELIPLILCTACLHPE

RELCH

541

Q9P260
LHLICLLEKVPCTLE

FEM1C

446

Q96JP0
VILNCSALPCLLHLL

KPNA6

331

O60684
HLLCEIPPLLKLACA

OR2AG2

176

A6NM03
LECLLTHCIKVPMLV

GNPTAB

126

Q3T906
HPVEEVGRLLLCCLL

HERC2

1431

O95714
VGRLLLCCLLKHEDL

HERC2

1436

O95714
KDPCELLHLCRLTIR

ASB17

251

Q8WXJ9
ITIIALDRCICVLHP

FPR3

116

P25089
PAILVIPCLLLIKCH

OR52A4P

156

A6NMU1
LLELFCKVPHLTKEC

GSTO2

116

Q9H4Y5
SSKVIIAHLPLLICC

PI4KA

471

P42356
LCHKILILLVILLCV

GDPD4

66

Q6W3E5
LPDVVCELSLLKTLH

LRRC10

136

Q5BKY1
HLLCEIPHLLKVACA

OR2AG1

176

Q9H205
DLCLLCTLPFVLHSL

GPR35

66

Q9HC97
GIHCETLKLLLPDCV

ITGAD

706

Q13349
LKPLDHLITRATLCC

SLC34A1

586

Q06495
LCICQILHEKITILV

ABCC4

576

O15439
AELKSICCIIHPESL

GTF2IRD2

646

Q86UP8
AELKSICCIIHPESL

GTF2IRD2B

646

Q6EKJ0
LERLIHPQLCELCIE

HPS1

171

Q92902
KCCLLTDQLPLAHHL

POLRMT

231

O00411
LTLTLLPSLELCLLC

FUZ

236

Q9BT04
PFLLTHLLLPCLKAC

DHRS13

146

Q6UX07
LLCEGLLHPDCKLQV

NLRP3

931

Q96P20
LVLHKQPREVCLCLL

GAS2

136

O43903
LLVSCVLLAKCLLHP

TPSG1

296

Q9NRR2
PCIIAVLCELHDGLL

RBL1

246

P28749
QSKTVLLLPCRHLCL

RNF26

386

Q9BY78
LALSCVELLLCLPVE

ZNF292

106

O60281
LCLHTKLLAPVNCPI

YTHDC2

776

Q9H6S0
LCAVVLKCLDPILTI

YTHDC2

846

Q9H6S0
LLDFCTLDIPHCVLL

ZZEF1

1041

O43149
LCKECPKIHIHIDRI

AGPAT5

251

Q9NUQ2
PLIILSHIVSLFCCI

TRPM7

1131

Q96QT4
LLKILQESFPCCIHV

TRIO

141

O75962
KSVPAIEICHLLCSV

ZBTB40

636

Q9NUA8
KCLDLLICHIVQELP

ULK4

801

Q96C45
VLLLCEGLRHPTCKL

NLRP12

901

P59046