Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	DNHD1 MYH9 ACSM4 MDN1 VWA8 DNAH17 CHD9 CHD8 CHD6 RFT1 DNAH9 TOP2A DYNC1I1 DYNC1I2 DNAH1	3.08e-08	614	83	15	GO:0140657
GeneOntologyMolecularFunction	microtubule motor activity	DNHD1 DNAH17 DNAH9 DYNC1I1 DYNC1I2 DNAH1	4.55e-07	70	83	6	GO:0003777
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNHD1 MYH9 DNAH17 DNAH9 DYNC1I1 DYNC1I2 DNAH1	6.03e-07	118	83	7	GO:0003774
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DNAH17 DNAH9 DNAH1	8.12e-07	18	83	4	GO:0008569
GeneOntologyMolecularFunction	actin binding	FLNB FLNC MYH9 DST SPATA31A1 SPATA31A3 SPATA31A7 TLN1 ACTN1 SPATA31A5 ARPC3	4.60e-06	479	83	11	GO:0003779
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNHD1 DNAH17 DNAH9 DNAH1	5.27e-06	28	83	4	GO:0051959
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNHD1 DNAH17 DNAH9 DNAH1	1.65e-05	37	83	4	GO:0045505
GeneOntologyMolecularFunction	molybdopterin cofactor binding	AOX1 XDH	2.53e-04	6	83	2	GO:0043546
GeneOntologyMolecularFunction	actin filament binding	FLNB FLNC MYH9 TLN1 ACTN1 ARPC3	3.68e-04	227	83	6	GO:0051015
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CHD9 CHD8 CHD6	4.86e-04	37	83	3	GO:0140658
GeneOntologyMolecularFunction	cytoskeletal protein binding	FLNB FLNC MYH9 DST SPATA31A1 SPATA31A3 SPATA31A7 TLN1 ACTN1 USH2A SPATA31A5 ARPC3 DYNC1I1	5.77e-04	1099	83	13	GO:0008092
GeneOntologyMolecularFunction	FAD binding	AOX1 XDH KDM1B	8.11e-04	44	83	3	GO:0071949
GeneOntologyMolecularFunction	integrin binding	SELP MYH9 DST TLN1 ACTN1	8.16e-04	175	83	5	GO:0005178
GeneOntologyMolecularFunction	dynein light chain binding	DYNC1I1 DYNC1I2	1.10e-03	12	83	2	GO:0045503
GeneOntologyMolecularFunction	vinculin binding	TLN1 ACTN1	1.29e-03	13	83	2	GO:0017166
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	CHD9 CHD8 CHD6 TOP2A	1.95e-03	127	83	4	GO:0008094
GeneOntologyCellularComponent	axonemal dynein complex	DNHD1 DNAH17 DNAH9 DYNC1I2 DNAH1	4.36e-08	25	83	5	GO:0005858
GeneOntologyCellularComponent	dynein complex	DNHD1 DNAH17 DNAH9 DYNC1I1 DYNC1I2 DNAH1	7.23e-08	54	83	6	GO:0030286
GeneOntologyCellularComponent	outer dynein arm	DNAH17 DNAH9 DYNC1I2	1.29e-05	12	83	3	GO:0036157
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	DNHD1 DST WDR11 DNAH17 DNAH9 DYNC1I1 DYNC1I2 DNAH1	3.76e-05	317	83	8	GO:0032838
GeneOntologyCellularComponent	microtubule associated complex	DNHD1 DNAH17 DNAH9 DYNC1I1 DYNC1I2 DNAH1	4.40e-05	161	83	6	GO:0005875
GeneOntologyCellularComponent	cytoplasmic region	DNHD1 DST WDR11 DNAH17 DNAH9 DYNC1I1 DYNC1I2 DNAH1	9.18e-05	360	83	8	GO:0099568
GeneOntologyCellularComponent	axoneme	DNHD1 WDR11 DNAH17 DNAH9 DYNC1I2 DNAH1	1.76e-04	207	83	6	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	DNHD1 WDR11 DNAH17 DNAH9 DYNC1I2 DNAH1	1.80e-04	208	83	6	GO:0097014
GeneOntologyCellularComponent	supramolecular fiber	COL5A2 FLNB FLNC MYH9 DST EHHADH DNAH17 ACTN1 ZW10 DNAH9 ARPC3 DYNC1I1 DYNC1I2 DNAH1	2.09e-04	1179	83	14	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	COL5A2 FLNB FLNC MYH9 DST EHHADH DNAH17 ACTN1 ZW10 DNAH9 ARPC3 DYNC1I1 DYNC1I2 DNAH1	2.24e-04	1187	83	14	GO:0099081
GeneOntologyCellularComponent	inner dynein arm	DNHD1 DNAH1	6.87e-04	10	83	2	GO:0036156
GeneOntologyCellularComponent	cell leading edge	MYH9 DST KCNB1 TLN1 ACTN1 USH2A ARPC3 GABBR1	8.31e-04	500	83	8	GO:0031252
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	MYH9 DST EHHADH DNAH17 ACTN1 ZW10 DNAH9 ARPC3 DYNC1I1 DYNC1I2 DNAH1	8.34e-04	899	83	11	GO:0099513
GeneOntologyCellularComponent	contractile actin filament bundle	FLNB MYH9 DST ACTN1	8.74e-04	107	83	4	GO:0097517
GeneOntologyCellularComponent	stress fiber	FLNB MYH9 DST ACTN1	8.74e-04	107	83	4	GO:0001725
GeneOntologyCellularComponent	actomyosin	FLNB MYH9 DST ACTN1	1.22e-03	117	83	4	GO:0042641
GeneOntologyCellularComponent	microtubule	DST EHHADH DNAH17 ZW10 DNAH9 DYNC1I1 DYNC1I2 DNAH1	1.25e-03	533	83	8	GO:0005874
GeneOntologyCellularComponent	actin filament bundle	FLNB MYH9 DST ACTN1	1.26e-03	118	83	4	GO:0032432
GeneOntologyCellularComponent	acrosomal vesicle	SPATA31A1 SPATA31A3 EHHADH SPATA31A7 SPATA31A5	1.38e-03	206	83	5	GO:0001669
GeneOntologyCellularComponent	focal adhesion	FLNB FLNC MYH9 DST TLN1 ACTN1 ARPC3	1.63e-03	431	83	7	GO:0005925
GeneOntologyCellularComponent	cell-substrate junction	FLNB FLNC MYH9 DST TLN1 ACTN1 ARPC3	1.90e-03	443	83	7	GO:0030055
GeneOntologyCellularComponent	Z disc	FLNB FLNC DST ACTN1	3.09e-03	151	83	4	GO:0030018
GeneOntologyCellularComponent	preribosome, large subunit precursor	MDN1 RRS1	3.11e-03	21	83	2	GO:0030687
GeneOntologyCellularComponent	histone methyltransferase complex	SETD1A PRMT5 CHD8	3.32e-03	75	83	3	GO:0035097
GeneOntologyCellularComponent	cytoplasmic dynein complex	DYNC1I1 DYNC1I2	4.06e-03	24	83	2	GO:0005868
GeneOntologyCellularComponent	neuron projection membrane	KCNB1 USH2A GABBR1	4.27e-03	82	83	3	GO:0032589
GeneOntologyCellularComponent	I band	FLNB FLNC DST ACTN1	4.33e-03	166	83	4	GO:0031674
MousePheno	abnormal placenta fetal blood space morphology	ADM MYH9 MECR	4.15e-06	8	60	3	MP:0011526
MousePheno	abnormal placenta intervillous maternal lacunae morphology	ADM MYH9 MECR	1.61e-05	12	60	3	MP:0011525
MousePheno	embryonic lethality prior to tooth bud stage	EHBP1 SETD1A FLNC URB1 MYH9 POGLUT1 PIK3C2A FKTN RRS1 TLN1 EIF4E PITPNB CHD8 CDC73 RFT1 ARPC3 TOP2A	4.69e-05	1383	60	17	MP:0013293
Domain	ATPase_dyneun-rel_AAA	MDN1 VWA8 DNAH9 DNAH1	3.34e-07	14	82	4	IPR011704
Domain	AAA_5	MDN1 VWA8 DNAH9 DNAH1	3.34e-07	14	82	4	PF07728
Domain	CH	EHBP1 FLNB FLNC EHBP1L1 DST ACTN1	4.00e-07	65	82	6	SM00033
Domain	CH	EHBP1 FLNB FLNC EHBP1L1 DST ACTN1	6.23e-07	70	82	6	PF00307
Domain	-	EHBP1 FLNB FLNC EHBP1L1 DST ACTN1	6.78e-07	71	82	6	1.10.418.10
Domain	CH	EHBP1 FLNB FLNC EHBP1L1 DST ACTN1	8.01e-07	73	82	6	PS50021
Domain	CH-domain	EHBP1 FLNB FLNC EHBP1L1 DST ACTN1	9.41e-07	75	82	6	IPR001715
Domain	BRK	CHD9 CHD8 CHD6	1.62e-06	6	82	3	SM00592
Domain	BRK_domain	CHD9 CHD8 CHD6	1.62e-06	6	82	3	IPR006576
Domain	BRK	CHD9 CHD8 CHD6	1.62e-06	6	82	3	PF07533
Domain	Actinin_actin-bd_CS	FLNB FLNC DST ACTN1	2.87e-06	23	82	4	IPR001589
Domain	ACTININ_2	FLNB FLNC DST ACTN1	2.87e-06	23	82	4	PS00020
Domain	ACTININ_1	FLNB FLNC DST ACTN1	2.87e-06	23	82	4	PS00019
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A5	1.74e-05	12	82	3	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A5	1.74e-05	12	82	3	IPR027970
Domain	2Fe-2S-bd	AOX1 XDH	1.90e-05	2	82	2	IPR002888
Domain	FAD_binding_5	AOX1 XDH	1.90e-05	2	82	2	PF00941
Domain	-	AOX1 XDH	1.90e-05	2	82	2	3.30.365.10
Domain	Ald_Oxase/Xan_DH_a/b	AOX1 XDH	1.90e-05	2	82	2	IPR000674
Domain	AldOxase/xan_DH_Mopterin-bd	AOX1 XDH	1.90e-05	2	82	2	IPR008274
Domain	DYNC1I1/DYNC1I2	DYNC1I1 DYNC1I2	1.90e-05	2	82	2	IPR025956
Domain	Ald_Xan_dh_C	AOX1 XDH	1.90e-05	2	82	2	PF01315
Domain	Fer2_2	AOX1 XDH	1.90e-05	2	82	2	PF01799
Domain	-	AOX1 XDH	1.90e-05	2	82	2	3.90.1170.50
Domain	Ald_Xan_dh_C2	AOX1 XDH	1.90e-05	2	82	2	PF02738
Domain	Dynein_IC2	DYNC1I1 DYNC1I2	1.90e-05	2	82	2	PF11540
Domain	CO_deh_flav_C	AOX1 XDH	1.90e-05	2	82	2	SM01092
Domain	CO_deh_flav_C	AOX1 XDH	1.90e-05	2	82	2	PF03450
Domain	CO_DH_flav_C	AOX1 XDH	1.90e-05	2	82	2	IPR005107
Domain	Ald_Oxase/xanthine_DH	AOX1 XDH	1.90e-05	2	82	2	IPR016208
Domain	-	AOX1 XDH	1.90e-05	2	82	2	1.10.150.120
Domain	Mopterin_DH_FAD-bd	AOX1 XDH	1.90e-05	2	82	2	IPR002346
Domain	Ald_Xan_dh_C	AOX1 XDH	1.90e-05	2	82	2	SM01008
Domain	Dynein_HC_stalk	DNHD1 DNAH9 DNAH1	2.87e-05	14	82	3	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH9 DNAH1	2.87e-05	14	82	3	IPR013602
Domain	DHC_N2	DNHD1 DNAH9 DNAH1	2.87e-05	14	82	3	PF08393
Domain	MT	DNHD1 DNAH9 DNAH1	2.87e-05	14	82	3	PF12777
Domain	DHC_fam	DNHD1 DNAH9 DNAH1	3.57e-05	15	82	3	IPR026983
Domain	Dynein_heavy_dom	DNHD1 DNAH9 DNAH1	3.57e-05	15	82	3	IPR004273
Domain	Dynein_heavy	DNHD1 DNAH9 DNAH1	3.57e-05	15	82	3	PF03028
Domain	MOLYBDOPTERIN_EUK	AOX1 XDH	5.70e-05	3	82	2	PS00559
Domain	OxRdtase_Mopterin-bd_dom	AOX1 XDH	5.70e-05	3	82	2	IPR000572
Domain	OxRdtase_Mopterin_BS	AOX1 XDH	5.70e-05	3	82	2	IPR022407
Domain	NT-C2	EHBP1 EHBP1L1	1.14e-04	4	82	2	PF10358
Domain	NT-C2	EHBP1 EHBP1L1	1.14e-04	4	82	2	IPR019448
Domain	Chromo_domain	CHD9 CHD8 CHD6	1.54e-04	24	82	3	IPR023780
Domain	2Fe2S_fd_BS	AOX1 XDH	1.89e-04	5	82	2	IPR006058
Domain	FAD-bd_2_sub1	AOX1 XDH	1.89e-04	5	82	2	IPR016167
Domain	-	AOX1 XDH	1.89e-04	5	82	2	3.30.43.10
Domain	2FE2S_FER_1	AOX1 XDH	1.89e-04	5	82	2	PS00197
Domain	Chromo	CHD9 CHD8 CHD6	1.97e-04	26	82	3	PF00385
Domain	CHROMO_1	CHD9 CHD8 CHD6	2.47e-04	28	82	3	PS00598
Domain	CHROMO_2	CHD9 CHD8 CHD6	2.47e-04	28	82	3	PS50013
Domain	Fer2	AOX1 XDH	2.82e-04	6	82	2	PF00111
Domain	2FE2S_FER_2	AOX1 XDH	2.82e-04	6	82	2	PS51085
Domain	FAD_PCMH	AOX1 XDH	2.82e-04	6	82	2	PS51387
Domain	CO_DH_flavot_FAD-bd_sub2	AOX1 XDH	2.82e-04	6	82	2	IPR016169
Domain	FAD-bd_2	AOX1 XDH	2.82e-04	6	82	2	IPR016166
Domain	-	AOX1 XDH	2.82e-04	6	82	2	3.30.465.10
Domain	2Fe-2S_ferredoxin-type	AOX1 XDH	2.82e-04	6	82	2	IPR001041
Domain	SNF2_N	CHD9 CHD8 CHD6	3.69e-04	32	82	3	IPR000330
Domain	Chromodomain-like	CHD9 CHD8 CHD6	3.69e-04	32	82	3	IPR016197
Domain	SNF2_N	CHD9 CHD8 CHD6	3.69e-04	32	82	3	PF00176
Domain	DUF3585	EHBP1 EHBP1L1	3.94e-04	7	82	2	IPR022735
Domain	DUF3585	EHBP1 EHBP1L1	3.94e-04	7	82	2	PF12130
Domain	Chromo/shadow_dom	CHD9 CHD8 CHD6	4.05e-04	33	82	3	IPR000953
Domain	CHROMO	CHD9 CHD8 CHD6	4.05e-04	33	82	3	SM00298
Domain	IG_FLMN	FLNB FLNC	8.38e-04	10	82	2	SM00557
Domain	Filamin	FLNB FLNC	1.02e-03	11	82	2	PF00630
Domain	FILAMIN_REPEAT	FLNB FLNC	1.02e-03	11	82	2	PS50194
Domain	Filamin/ABP280_rpt	FLNB FLNC	1.02e-03	11	82	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNB FLNC	1.02e-03	11	82	2	IPR017868
Domain	-	GLA FUCA1	1.67e-03	14	82	2	2.60.40.1180
Domain	Dynein_heavy_chain_D4_dom	DNAH9 DNAH1	1.67e-03	14	82	2	IPR024317
Domain	Beta-grasp_dom	AOX1 XDH	1.67e-03	14	82	2	IPR012675
Domain	AAA_8	DNAH9 DNAH1	1.67e-03	14	82	2	PF12780
Domain	-	AOX1 XDH	1.67e-03	14	82	2	3.10.20.30
Domain	Glyco_hydro_b	GLA FUCA1	1.93e-03	15	82	2	IPR013780
Domain	ADH_N	MECR VAT1L	2.20e-03	16	82	2	PF08240
Domain	PKS_ER	MECR VAT1L	2.20e-03	16	82	2	SM00829
Domain	PKS_ER	MECR VAT1L	2.20e-03	16	82	2	IPR020843
Domain	ADH_N	MECR VAT1L	2.20e-03	16	82	2	IPR013154
Domain	-	MECR VAT1L	2.78e-03	18	82	2	3.90.180.10
Domain	ADH_zinc_N	MECR VAT1L	3.10e-03	19	82	2	PF00107
Domain	ADH_SF_Zn-type	MECR VAT1L	3.10e-03	19	82	2	IPR002085
Domain	ADH_C	MECR VAT1L	3.10e-03	19	82	2	IPR013149
Domain	P-loop_NTPase	NDST3 DNHD1 MYH9 MDN1 VWA8 CHD9 CHD8 CHD6 DNAH9 DNAH1	3.92e-03	848	82	10	IPR027417
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A5	5.46e-10	6	87	4	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A5	5.46e-10	6	87	4	25930072
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	FLNB FLNC MYH9 MDN1 GLA TLN1 CNDP2 XDH ARPC3 DYNC1I2	1.60e-08	344	87	10	30333137
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	TCAF2 FLNB FLNC MYH9 EHBP1L1 DST TLN1 CNDP2 CDC73 DYNC1I2	2.46e-08	360	87	10	33111431
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	CMBL FLNB FLNC MYH9 MDN1 DST PRMT5 TLN1 CNDP2 CHD8 ACTN1 ARPC3 DNAH1	1.08e-07	807	87	13	30575818
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SETD1A FLNB FLNC URB1 MYH9 MDN1 DST WDR11 PIK3C2A RRS1 TLN1 THUMPD3 CHD8 ACTN1 TOP2A DYNC1I2	2.21e-07	1353	87	16	29467282
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A5	3.74e-07	24	87	4	32212159
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNB FLNC URB1 MYH9 MDN1 DST RRS1 PRMT5 TLN1 CHD8 ACTN1	7.23e-07	653	87	11	22586326
Pubmed	MYH9-dependent polarization of ATG9B promotes colorectal cancer metastasis by accelerating focal adhesion assembly.	FLNB MYH9 TLN1	8.39e-07	8	87	3	34131310
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	FLNB MYH9 MDN1 DST RRS1 TLN1 CNDP2 ACTN1 ARPC3 TOP2A	9.95e-07	538	87	10	28524877
Pubmed	Transport of the outer dynein arm complex to cilia requires a cytoplasmic protein Lrrc6.	DNAH9 DYNC1I1 DYNC1I2	1.26e-06	9	87	3	27353389
Pubmed	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.	FLNB FLNC TLN1	1.26e-06	9	87	3	11807098
Pubmed	USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1.	FLNB FLNC MYH9	2.46e-06	11	87	3	19015242
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	FLNB FLNC MYH9 EHBP1L1 GLA PRMT5 TLN1 EIF4E THUMPD3 CNDP2 ACTN1 CDC73 ZW10 ARPC3 DYNC1I2	3.03e-06	1455	87	15	22863883
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	FLNB FLNC URB1 MYH9 MDN1 PRMT5 TLN1 ACTN1 TOP2A	3.57e-06	484	87	9	31995728
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	URB1 MDN1 DST WDR11 PIK3C2A RRS1 PRMT5 TLN1 EIF4E CHD8 CHD6 ACTN1 KDM1B ARPC3 MED13	4.28e-06	1497	87	15	31527615
Pubmed	Multiple mouse chromosomal loci for dynein-based motility.	DNAH9 DYNC1I1 DYNC1I2 DNAH1	6.00e-06	47	87	4	8812413
Pubmed	Cloning and characterization of two cytoplasmic dynein intermediate chain genes in mouse and human.	DYNC1I1 DYNC1I2	6.19e-06	2	87	2	10049579
Pubmed	Increased platelet and microparticle activation in HIV infection: upregulation of P-selectin and tissue factor expression.	SELP F3	6.19e-06	2	87	2	22156911
Pubmed	PRMT5 is essential for the eIF4E-mediated 5'-cap dependent translation.	PRMT5 EIF4E	6.19e-06	2	87	2	25234597
Pubmed	Cancer cell-derived microparticles bearing P-selectin glycoprotein ligand 1 accelerate thrombus formation in vivo.	SELP F3	6.19e-06	2	87	2	19667060
Pubmed	The limits of promiscuity: isoform-specific dimerization of filamins.	FLNB FLNC	6.19e-06	2	87	2	12525170
Pubmed	A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.	FLNB FLNC	6.19e-06	2	87	2	9694715
Pubmed	Nitrite reductase activity of rat and human xanthine oxidase, xanthine dehydrogenase, and aldehyde oxidase: evaluation of their contribution to NO formation in vivo.	AOX1 XDH	6.19e-06	2	87	2	25537183
Pubmed	Mouse cytoplasmic dynein intermediate chains: identification of new isoforms, alternative splicing and tissue distribution of transcripts.	DYNC1I1 DYNC1I2	6.19e-06	2	87	2	20657784
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	CMBL DNHD1 FLNB MYH9 PIK3C2A TLN1 AOX1 CNDP2 SLC13A3 FUCA1 ACTN1 ARPC3	8.58e-06	1016	87	12	19056867
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	MYH9 DST PRMT5 TLN1 CHD8 ACTN1	1.06e-05	197	87	6	20811636
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	FLNB FLNC TLN1	1.20e-05	18	87	3	12119179
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	EHBP1 FLNB FLNC MYH9 DST WDR11 TLN1 RFT1 ZW10	1.28e-05	568	87	9	37774976
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FLNB FLNC MYH9 MDN1 DST RRS1 ARHGAP12 CHD6 ACTN1 LYST TOP2A MED13 DYNC1I1 DYNC1I2	1.33e-05	1442	87	14	35575683
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FLNB URB1 MYH9 MDN1 DST PRMT5 TLN1 EIF4E CCDC87 CHD6	1.56e-05	736	87	10	29676528
Pubmed	Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3.	PRMT5 EIF4E	1.85e-05	3	87	2	26078354
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNB FLNC	1.85e-05	3	87	2	11252955
Pubmed	The vinculin binding sites of talin and alpha-actinin are sufficient to activate vinculin.	TLN1 ACTN1	1.85e-05	3	87	2	16407299
Pubmed	Arginine methyltransferase inhibitor 1 inhibits gastric cancer by downregulating eIF4E and targeting PRMT5.	PRMT5 EIF4E	1.85e-05	3	87	2	28987382
Pubmed	Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin.	SELP F3	1.85e-05	3	87	2	12782720
Pubmed	NMMHC IIA inhibition impedes tissue factor expression and venous thrombosis via Akt/GSK3β-NF-κB signalling pathways in the endothelium.	MYH9 F3	1.85e-05	3	87	2	25881103
Pubmed	Distinct Pathogenesis of Pancreatic Cancer Microvesicle-Associated Venous Thrombosis Identifies New Antithrombotic Targets In Vivo.	SELP F3	1.85e-05	3	87	2	29419408
Pubmed	Polymorphism of genes involved in purine metabolism (XDH, AOX1, MOCOS) in kidney transplant recipients receiving azathioprine.	AOX1 XDH	1.85e-05	3	87	2	22495427
Pubmed	The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.	CHD8 CHD6	1.85e-05	3	87	2	28533432
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNB FLNC	1.85e-05	3	87	2	12393796
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNB FLNC	1.85e-05	3	87	2	11153914
Pubmed	Novel pharmacogenetic markers for treatment outcome in azathioprine-treated inflammatory bowel disease.	AOX1 XDH	1.85e-05	3	87	2	19500084
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SETD1A FLNC URB1 EHBP1L1 MDN1 DST VWA8 RRS1 TLN1 CHD8 LYST MED13	1.97e-05	1105	87	12	35748872
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	COL5A2 FLNB MYH9 DST TLN1 CHD8 TOP2A	2.06e-05	332	87	7	37433992
Pubmed	Downregulation of the FBXO43 gene inhibits tumor growth in human breast cancer by limiting its interaction with PCNA.	FLNB FLNC MYH9 TLN1	2.20e-05	65	87	4	34645483
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	URB1 DST KIAA0232 TLN1 CHD8 CHD6	2.24e-05	225	87	6	12168954
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	EHBP1 FLNB MYH9 EHBP1L1 TLN1 DNAH9	2.29e-05	226	87	6	31452512
Pubmed	Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.	FLNB FLNC TLN1 ACTN1 CDC73 ARPC3	2.86e-05	235	87	6	28378594
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	FLNB FLNC MYH9 MDN1 DST PRMT5 TLN1 EIF4E ACTN1 ZW10 ARPC3 DYNC1I2	2.89e-05	1149	87	12	35446349
Pubmed	A human MAP kinase interactome.	EHBP1 FLNC MYH9 DST KIAA0232 CHD8 CHD6 ACTN1	3.05e-05	486	87	8	20936779
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	SETD1A FLNB FLNC MYH9 PRMT5 TLN1 CHD9 DYNC1I2	3.43e-05	494	87	8	26831064
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNB FLNC	3.70e-05	4	87	2	11739414
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNB FLNC	3.70e-05	4	87	2	22802962
Pubmed	Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.	ZW10 DYNC1I1	3.70e-05	4	87	2	19229290
Pubmed	Structural dynamics of alpha-actinin-vinculin interactions.	TLN1 ACTN1	3.70e-05	4	87	2	15988023
Pubmed	A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair.	FLNB FLNC MYH9 ACTN1 CDC73	4.26e-05	153	87	5	27462432
Pubmed	Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers.	FLNB FLNC MYH9 TLN1 EIF4E ACTN1	4.91e-05	259	87	6	31162944
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	FLNB FLNC URB1 MDN1 DST RRS1 PRMT5 TLN1 ACTN1 ARPC3 TOP2A	4.97e-05	1024	87	11	24711643
Pubmed	Linking nuclear matrix-localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z.	FLNB FLNC MYH9 ACTN1 USH2A	5.12e-05	159	87	5	34537242
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	WDR11 KIAA0232 PRMT5 TLN1 ARHGAP12 EIF4E ARPC3 TOP2A DYNC1I1 DYNC1I2	5.44e-05	853	87	10	28718761
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	FLNB LIPT1 URB1 MDN1 DST PIK3C2A VWA8 RRS1 PRMT5 TLN1 ZW10 ARPC3 TOP2A	5.88e-05	1440	87	13	30833792
Pubmed	Interaction of SQSTM1 with the motor protein dynein--SQSTM1 is required for normal dynein function and trafficking.	DYNC1I1 DYNC1I2	6.16e-05	5	87	2	25015291
Pubmed	Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma.	DYNC1I1 DYNC1I2	6.16e-05	5	87	2	30250299
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNB FLNC	6.16e-05	5	87	2	19366992
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNB FLNC	6.16e-05	5	87	2	12006559
Pubmed	Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity.	TLN1 F3	6.16e-05	5	87	2	31048328
Pubmed	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.	FLNB FLNC	6.16e-05	5	87	2	17360453
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	FLNB FLNC MYH9 MDN1 PRMT5 TLN1 ZW10 ARPC3 TOP2A	7.04e-05	707	87	9	19738201
Pubmed	Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.	FLNB FLNC DST TLN1 ACTN1 ARPC3	8.32e-05	285	87	6	21423176
Pubmed	A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling.	FLNB MYH9 PRMT5	8.55e-05	34	87	3	12577067
Pubmed	MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer.	PRMT5 EIF4E KDM1B ARPC3 TOP2A DYNC1I2	8.64e-05	287	87	6	36180891
Pubmed	Nucleolar proteome dynamics.	MYH9 MDN1 RRS1 CDC73 ADARB2 ARPC3 TOP2A	8.94e-05	419	87	7	15635413
Pubmed	Animal models of lysosomal disease: an overview.	DYNC1I1 DYNC1I2	9.22e-05	6	87	2	9728334
Pubmed	Tissue factor and IL8 production by P-selectin-dependent platelet-monocyte aggregates in whole blood involves phosphorylation of Lyn and is inhibited by IL10.	SELP F3	9.22e-05	6	87	2	18363812
Pubmed	Rod/Zw10 complex is required for PIASy-dependent centromeric SUMOylation.	ZW10 TOP2A	9.22e-05	6	87	2	20696768
Pubmed	Vector-capping: a simple method for preparing a high-quality full-length cDNA library.	FLNB MYH9	9.22e-05	6	87	2	16106752
Pubmed	The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins.	MYH9 ARPC3	9.22e-05	6	87	2	25926623
Pubmed	Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases.	FLNB MYH9 RRS1 EIF4E ACTN1 ARPC3	1.00e-04	295	87	6	26209609
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	URB1 MYH9 MDN1 GLA WDR11 VWA8 RRS1 RFT1 DYNC1I2	1.15e-04	754	87	9	33060197
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	FLNB FLNC MYH9 DST ACTN1	1.22e-04	191	87	5	33762435
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	FLNC CWF19L2 MYH9 TLN1 CHD8 ACTN1 TOP2A	1.28e-04	444	87	7	34795231
Pubmed	Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.	LIPT1 CCDC87 RFT1 DNAH1	1.29e-04	102	87	4	21926972
Pubmed	Temporal profiles of the subcellular localization of Bim, a BH3-only protein, during middle cerebral artery occlusion in mice.	DYNC1I1 DYNC1I2	1.29e-04	7	87	2	12142566
Pubmed	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.	FLNB FLNC	1.29e-04	7	87	2	16076904
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH17 DNAH9	1.29e-04	7	87	2	31178125
Pubmed	A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins.	DYNC1I1 DYNC1I2	1.29e-04	7	87	2	11751894
Pubmed	A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system.	DYNC1I1 DYNC1I2	1.29e-04	7	87	2	11163259
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SETD1A MDN1 CHD9 DNAH9	1.39e-04	104	87	4	9205841
Pubmed	HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress.	FLNB MYH9 ACTN1	1.50e-04	41	87	3	24614889
Pubmed	Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2.	FLNB FLNC EHHADH	1.50e-04	41	87	3	18157088
Pubmed	TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.	RRS1 CHD9 CHD8 CHD6	1.66e-04	109	87	4	33554859
Pubmed	The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions.	TLN1 ACTN1	1.72e-04	8	87	2	12695497
Pubmed	MEKK4 signaling regulates filamin expression and neuronal migration.	FLNB FLNC	1.72e-04	8	87	2	17145501
Pubmed	beta-Dystroglycan modulates the interplay between actin and microtubules in human-adhered platelets.	TLN1 ACTN1	1.72e-04	8	87	2	18341635
Pubmed	4D intravital imaging studies identify platelets as the predominant cellular procoagulant surface in a mouse hemostasis model.	SELP F3	1.72e-04	8	87	2	38820498
Pubmed	USP35 promotes cell proliferation and chemotherapeutic resistance through stabilizing FUCA1 in colorectal cancer.	PRMT5 FUCA1	1.72e-04	8	87	2	36864055
Pubmed	HIV-1 uncoating is facilitated by dynein and kinesin 1.	DYNC1I1 DYNC1I2	1.72e-04	8	87	2	25231297
Pubmed	CFAP43 modulates ciliary beating in mouse and Xenopus.	DNAH9 DNAH1	1.72e-04	8	87	2	31884020
Pubmed	HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus.	DYNC1I1 DYNC1I2	1.72e-04	8	87	2	25818806
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	9.87e-05	8	87	2	chr9q12
Cytoband	8q13.1	RRS1 C8orf44	7.28e-04	21	87	2	8q13.1
Cytoband	9p13.1	SPATA31A1 SPATA31A3	9.54e-04	24	87	2	9p13.1
Cytoband	3p21.1	RFT1 DNAH1	2.91e-03	42	87	2	3p21.1
GeneFamily	Dyneins, axonemal	DNAH17 DNAH9 DNAH1	8.33e-06	17	43	3	536
GeneFamily	Dyneins, cytoplasmic	DYNC1I1 DYNC1I2	4.24e-04	13	43	2	538
GeneFamily	WD repeat domain containing	WDR11 LYST DYNC1I1 DYNC1I2	3.41e-03	262	43	4	362
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELP GABBR1	8.12e-03	57	43	2	1179
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	EHBP1 COL5A2 FLNB MDN1 DST ARHGAP12 EIF4E AFF1 CHD9 F3 TOP2A MED13	3.08e-08	466	84	12	M13522
Coexpression	YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5	ADM COL5A2 CNDP2 XDH	2.89e-06	31	84	4	M16708
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	EHBP1 COL5A2 FLNB MDN1 DST PIK3C2A ARHGAP12 EIF4E AFF1 CHD9 F3 TOP2A MED13	3.23e-06	856	84	13	M4500
Coexpression	YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5	ADM COL5A2 CNDP2 XDH	3.30e-06	32	84	4	MM1278
Coexpression	GSE9960_HEALTHY_VS_SEPSIS_PBMC_UP	FKTN VAT1L ACTN1 RFT1 F3 TOP2A	3.94e-05	195	84	6	M7125
ToppCell	severe-CD8+_T_naive\|World / disease stage, cell group and cell class	DNHD1 MECR FAM24B ACTN1 RFT1 ZW10	1.50e-06	181	87	6	69eeeb7f326e230b07495d557f708fbe3312ac0a
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NDST3 MYH9 PLPPR4 VAT1L ACTN1 ADARB2	2.18e-06	193	87	6	000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CMBL VWA8 EHHADH CNDP2 SLC13A3	2.15e-05	171	87	5	48fc4eca18b102b5ec5050f758281292ee8e10c6
ToppCell	Pericytes-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	COL5A2 KCNB1 BCHE VAT1L DYNC1I1	2.15e-05	171	87	5	bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCell	droplet-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CMBL VWA8 EHHADH CNDP2 SLC13A3	2.15e-05	171	87	5	05fcc72df50a380a913821b5781d9621df37d328
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH9 DST PIK3C2A EHHADH TMPRSS6	2.27e-05	173	87	5	e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCell	facs-Large_Intestine-Proximal-3m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH9 DST PIK3C2A EHHADH TMPRSS6	2.27e-05	173	87	5	99532bb768ee35fed939a377acb5215d3f8904bd
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	MDN1 DST KCNB1 ARHGAP12 GABBR1	2.53e-05	177	87	5	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	severe-CD8+_T_naive\|severe / disease stage, cell group and cell class	DNHD1 MECR FAM24B ACTN1 ZW10	2.75e-05	180	87	5	94fe530367b170777f4051a4034cff06d80dbb83
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NDST3 MYH9 PLPPR4 ACTN1 ADARB2	3.47e-05	189	87	5	b6d5dec55bf352f6ae19d8f488ae70aa10fb9a8f
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NDST3 MYH9 PLPPR4 ACTN1 ADARB2	3.47e-05	189	87	5	f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A2 FLNC AOX1 BCHE VAT1L	3.93e-05	194	87	5	c578cf7c6b4d6f31f87dde8845de5b3891f16822
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibro-meso\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A2 FLNC AOX1 BCHE VAT1L	3.93e-05	194	87	5	f4286ae7bb8350c42d50727ee8688b80129714f6
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A2 FLNC AOX1 BCHE VAT1L	3.93e-05	194	87	5	87461bd6d7f702c0a0f5e0c8ace3049125a51f9a
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NDST3 MYH9 PLPPR4 ACTN1 ADARB2	3.93e-05	194	87	5	67f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADM KCNB1 AOX1 ACTN1 DNAH9	4.02e-05	195	87	5	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADM KCNB1 AOX1 ACTN1 DNAH9	4.02e-05	195	87	5	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	COVID-19_Severe-PLT_0\|COVID-19_Severe / Disease Group and Platelet Clusters	SELP MYH9 GLA TLN1 ACTN1	4.22e-05	197	87	5	dbdeefa72d10f2c5f75ad5aac6f31a892d4e94a9
ToppCell	COVID-19-kidney-PCT-S3-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CMBL EHHADH AOX1 CNDP2 SLC13A3	4.33e-05	198	87	5	36a60397f49f5381ae377155b73e1891448846b7
ToppCell	Fibroblasts\|World / lung cells shred on cell class, cell subclass, sample id	COL5A2 FLNC PLPPR4 AOX1 BCHE	4.43e-05	199	87	5	e2b6752fcabd5249a166486ae6796f2c97c1fcaf
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CMBL EHHADH AOX1 CNDP2 SLC13A3	4.54e-05	200	87	5	e118d5e6e5d5bb808877a6667668c36f21afad5b
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CMBL EHHADH AOX1 CNDP2 SLC13A3	4.54e-05	200	87	5	234e5a927eec0e235226586451ba3754c8a14169
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	SELP FLNB EHBP1L1 ACTN1 LYST	4.54e-05	200	87	5	e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CMBL TCAF2 FLNC SLC13A3	1.19e-04	129	87	4	856255fbfc7f95642000cfd7704141b2388f7c5c
ToppCell	COVID-19_Convalescent-PLT_3\|World / Disease Group and Platelet Clusters	FLNB VWA8 CHD6 KDM1B	1.51e-04	137	87	4	bb54bb81b450462ad521b57e1a07a80ce1678e67
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	NDST3 CCDC87 VAT1L DNAH9	1.82e-04	144	87	4	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell	Parenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	KCNB1 AOX1 F3 GABBR1	1.87e-04	145	87	4	e808502fa52baf1c400f3c9b918a167127e78af9
ToppCell	Adult-Mesenchymal-chondrocyte-D122\|Adult / Lineage, Cell type, age group and donor	COL5A2 AOX1 BCHE ADARB2	2.02e-04	148	87	4	81a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCell	droplet-Liver-Npc-18m-Epithelial-Hepatocyte_(Midlobular)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CMBL FLNB TMPRSS6 DNAH1	2.19e-04	151	87	4	86efabf27c264c856dca1cffacb16cef52e9863c
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_12\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL5A2 FKTN PRMT5 TOP2A	2.36e-04	154	87	4	3c9d38709f507e91ec3bcc6184cbbfa9b1250128
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_12\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	COL5A2 FKTN PRMT5 TOP2A	2.36e-04	154	87	4	1ad4152a3e4bf5912954235fe21c2447e99f3de7
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CMBL FLNC AOX1 SLC13A3	2.36e-04	154	87	4	65dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCell	LPS-antiTNF-Endothelial-Epi-like-Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CMBL RRS1 VWA3B F3	2.54e-04	157	87	4	abfd05ed993b80822739f47a735f154092a23632
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	MDN1 DST KCNB1 GABBR1	2.79e-04	161	87	4	347edb0de10850b7d16c40945751033289289c9b
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FKTN RRS1 TMPRSS6 ADARB2	2.86e-04	162	87	4	56f1789e69a6cb29956e46aba92b290847327c1f
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNB1 VWA3B DNAH9 PGBD5	2.99e-04	164	87	4	9e16e52f5a634585f26021bcce9b5d5992ff6db0
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CMBL EHHADH CNDP2 SLC13A3	3.06e-04	165	87	4	082f62f759a0b16ab56fad6dd4c4dd70b4f18a5c
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CMBL EHHADH CNDP2 SLC13A3	3.13e-04	166	87	4	8ab18c9d911eb3a9970bba7a769294b0927538f7
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CMBL EHHADH CNDP2 SLC13A3	3.13e-04	166	87	4	0868f45d8d39ad39b5cee5e81ac3dd4dc512775d
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLPPR4 EHHADH TMPRSS6 USH2A	3.21e-04	167	87	4	ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PRMT5 AOX1 AGBL3 TIGD6	3.28e-04	168	87	4	53a982869dbf14f6a948589be9f2f3df3b9a7e97
ToppCell	droplet-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CMBL EHHADH CNDP2 SLC13A3	3.28e-04	168	87	4	dd48da83c32d41a62f80cd7e5e5c64e42776fa27
ToppCell	droplet-Kidney-nan-18m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLPPR4 EHHADH TMPRSS6 USH2A	3.35e-04	169	87	4	f00741203efa0b948db7223ee8c19bdd0918258a
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 USH2A DNAH9 DNAH1	3.35e-04	169	87	4	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH9 XDH ACTN1 LYST	3.51e-04	171	87	4	ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH9 XDH ACTN1 LYST	3.51e-04	171	87	4	97ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC TMPRSS6 USH2A DNAH9	3.66e-04	173	87	4	66f37c1437705734b20601656fa4aa1d92ca30be
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC TMPRSS6 USH2A DNAH9	3.66e-04	173	87	4	649b08a409095592cccf31883be69c754411280d
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SETD1A CWF19L2 MDN1 PITPNB	3.83e-04	175	87	4	bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCell	facs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLPPR4 EHHADH TMPRSS6 CNDP2	3.83e-04	175	87	4	076ad81d6cbeea5512393d192af3ab5aa1f82975
ToppCell	facs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLPPR4 EHHADH TMPRSS6 CNDP2	3.83e-04	175	87	4	445ccb9744a3a9ff37164c532afbe769d306b6c8
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRC53 VWA3B SLC13A3 DNAH9	3.91e-04	176	87	4	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH9 XDH ACTN1 LYST	4.00e-04	177	87	4	065bebd22031f143e90a407f952b444a3f8818c7
ToppCell	facs-Marrow-Granulocytes-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH9 XDH ACTN1 LYST	4.00e-04	177	87	4	eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP DST KCNB1 PRR15	4.08e-04	178	87	4	5cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CMBL EHHADH AOX1 SLC13A3	4.08e-04	178	87	4	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	facs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP DST KCNB1 PRR15	4.08e-04	178	87	4	f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADM KCNB1 TMPRSS6 F3	4.08e-04	178	87	4	6d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADM KCNB1 TMPRSS6 F3	4.08e-04	178	87	4	d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCell	COVID-19_Mild-NK_CD56bright\|COVID-19_Mild / Disease condition and Cell class	FLNB DST CHD9 LYST	4.17e-04	179	87	4	90e7a4af195aa2332b07a9f06cde63e72ff49255
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CMBL EHHADH AOX1 SLC13A3	4.17e-04	179	87	4	78fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRC53 VWA3B KDM1B DNAH1	4.26e-04	180	87	4	92fb01b91261b3103454924cde56add337b41844
ToppCell	droplet-Limb_Muscle-Pre-Sort\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP DST TMPRSS6 ACTN1	4.26e-04	180	87	4	af2bafcd1b2082629de3ea336711add01565c4c4
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CMBL EHHADH AOX1 SLC13A3	4.26e-04	180	87	4	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP DST TMPRSS6 ACTN1	4.26e-04	180	87	4	f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCell	IIH-plasma\|IIH / Condition, Cell_class and T cell subcluster	ADM AOX1 SLC13A3 F3	4.35e-04	181	87	4	13d1f31bcbac21aea91de74f51eed549ec61003e
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNB1 FKTN TMPRSS6 F3	4.35e-04	181	87	4	35eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCell	IIH-plasma-\|IIH / Condition, Cell_class and T cell subcluster	ADM AOX1 SLC13A3 F3	4.35e-04	181	87	4	140ac43dc6b89396872f908c14c89278f6d982b2
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNB1 FKTN TMPRSS6 F3	4.35e-04	181	87	4	e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELP COL5A2 FLNB PRR15	4.44e-04	182	87	4	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELP COL5A2 FLNB PRR15	4.44e-04	182	87	4	d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP COL5A2 DST PRR15	4.44e-04	182	87	4	aa113a0d2c1d28bda24cbb1221afd21b5628dc6d
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELP COL5A2 FLNB DST	4.53e-04	183	87	4	3427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	XDH CHD6 RFT1 TOP2A	4.53e-04	183	87	4	ba7753e9fe2a6a87c5264f299ac97da2ddbda178
ToppCell	10x5'v1-week_12-13-Hematopoietic-MK-MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SELP TLN1 ACTN1 GABBR1	4.53e-04	183	87	4	6cbc88c27dc957d182526e84824f70c8e860bf74
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNC BCHE VAT1L ACTN1	4.53e-04	183	87	4	61a73de857f4ae02dcba3af348f436f602b28ff2
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NDST3 PLPPR4 ACTN1 ADARB2	4.53e-04	183	87	4	e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCell	COVID-19-kidney-PCT-S1/S2\|kidney / Disease (COVID-19 only), tissue and cell type	CMBL EHHADH AOX1 SLC13A3	4.62e-04	184	87	4	dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell	tumor_Lung-Fibroblasts-Mesothelial_cells\|tumor_Lung / Location, Cell class and cell subclass	FLNC KCNB1 AOX1 BCHE	4.62e-04	184	87	4	b0a251030d127858e68cf164be158f209a4d720f
ToppCell	Brain_organoid-organoid_Kanton_Nature\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	CHD9 BCHE CHD6 DYNC1I2	4.72e-04	185	87	4	857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELP COL5A2 FLNB DST	4.72e-04	185	87	4	87151ab95530e70d61328b336518df58db584acb
ToppCell	facs-Bladder-nan-18m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADM EIF4E F3 PGBD5	4.72e-04	185	87	4	3e00879466e626aa8604efecfc4678d64f54dbfc
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CMBL EHHADH AOX1 SLC13A3	4.72e-04	185	87	4	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	facs-Bladder-nan-18m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADM EIF4E F3 PGBD5	4.72e-04	185	87	4	3dc5812c961ff209f197ff4cbfb90009c0537550
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A2 DST PLPPR4 AOX1	4.82e-04	186	87	4	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELP COL5A2 FLNC PRR15	4.82e-04	186	87	4	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL5A2 FLNC AOX1 BCHE	4.82e-04	186	87	4	7812ed80d2378aca9957ef22fc3c8fb7fb58434b
ToppCell	P28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SELP EHBP1L1 KCNB1 BCHE	4.82e-04	186	87	4	153c8b2fd8a6e2141ca97c626f82e5f081f3180a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CMBL EHHADH AOX1 SLC13A3	4.82e-04	186	87	4	8287146f0ba415ea04475588117d4668ae00f75c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CMBL EHHADH AOX1 SLC13A3	4.91e-04	187	87	4	71eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	CMBL EHHADH AOX1 SLC13A3	4.91e-04	187	87	4	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLNB DST CENATAC PGBD5	4.91e-04	187	87	4	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	COVID-19-kidney-Mito-rich_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	CMBL EHHADH AOX1 SLC13A3	4.91e-04	187	87	4	738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELP FLNB DST PRR15	4.91e-04	187	87	4	7170694a1b86fe8d84d96c880ffe57af09bdc026
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SELP DST KCNB1 DYNC1I1	5.01e-04	188	87	4	5eb107122064f0a99dfd445cc87d3766f7257216
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CWF19L2 CCDC87 VWA3B TOP2A	5.01e-04	188	87	4	0476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNC BCHE VAT1L ACTN1	5.01e-04	188	87	4	879de94924de978478696fc7838e05a4d795b905
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NDST3 PLPPR4 ACTN1 ADARB2	5.01e-04	188	87	4	3004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNC AOX1 BCHE VAT1L	5.01e-04	188	87	4	e82104f71bcdab7392fdb076dc3560255964fd9e
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNC BCHE VAT1L ACTN1	5.12e-04	189	87	4	ab7ece0a517499b70b7754720d3e434765363af6
Drug	alternariol	GLA EIF4E AOX1 XDH BCHE	3.41e-09	17	83	5	CID005359485
Drug	NSC344479	KLHDC3 AOX1 XDH SLC13A3	7.00e-06	34	83	4	CID000023850
Drug	5-hydroxypyrazinoic acid	AOX1 XDH	1.31e-05	2	83	2	CID000161825
Drug	5-hydroxypyrazinamide	AOX1 XDH	1.31e-05	2	83	2	CID000151823
Drug	AC1Q5V6O	AOX1 F3	1.31e-05	2	83	2	CID000188384
Drug	Isoflavones	MYH9 PIK3C2A EHHADH AOX1 TMX4 ACTN1 TOP2A	1.50e-05	218	83	7	ctd:D007529
Drug	IC261	DNAH17 DNAH9 DYNC1I1 DYNC1I2 DNAH1	2.69e-05	96	83	5	CID000003674
Drug	acridone	EIF4E AOX1 LYST	3.06e-05	17	83	3	CID000002015
Drug	2-hydroxypurine	AOX1 XDH	3.93e-05	3	83	2	CID000075323
Drug	voachalotine	BCHE F3	3.93e-05	3	83	2	CID000099116
Drug	ethyl methylphosphonate	PIK3C2A BCHE	3.93e-05	3	83	2	CID000449085
Drug	I-Hg	DST AOX1 LYST	4.34e-05	19	83	3	CID000447029
Drug	acetate	FLNB LIPT1 DST KLHDC3 RRS1 DNAH17 XDH BCHE DNAH9 DNAH1	6.39e-05	599	83	10	CID000000175
Drug	hMCP	SELP AOX1 LYST	6.84e-05	22	83	3	CID006450018
Drug	ethylsarin	PIK3C2A BCHE	7.84e-05	4	83	2	CID000160541
Drug	AC1L212F	AOX1 XDH	7.84e-05	4	83	2	CID000013118
Drug	UM-272	PIK3C2A BCHE	7.84e-05	4	83	2	CID000038088
Drug	AC1L3UXH	AOX1 XDH	7.84e-05	4	83	2	CID000065446
Drug	picrolonic acid	AOX1 XDH	7.84e-05	4	83	2	CID000068369
Drug	plasmocid	GLA PIK3C2A	7.84e-05	4	83	2	CID000120201
Drug	nicotinohydroxamic acid	AOX1 BCHE	7.84e-05	4	83	2	CID000071211
Drug	phenanthridine	AOX1 XDH F3	7.85e-05	23	83	3	CID000009189
Drug	Pyrithyldione [77-04-3]; Up 200; 24uM; MCF7; HT_HG-U133A	COL5A2 URB1 EHBP1L1 DNAH17 LYST TIGD6	8.44e-05	197	83	6	6801_UP
Drug	WY-14643; Down 200; 100uM; PC3; HG-U133A	NDST3 COL5A2 URB1 EHBP1L1 SLC13A3 CDC73	8.68e-05	198	83	6	481_DN
Drug	Butamben [94-25-7]; Up 200; 20.6uM; MCF7; HT_HG-U133A	COL5A2 URB1 PLPPR4 TMPRSS6 CCDC87 C8orf44	8.92e-05	199	83	6	6093_UP
Disease	CHARGE syndrome (implicated_via_orthology)	CHD9 CHD8 CHD6	7.45e-07	7	83	3	DOID:0050834 (implicated_via_orthology)
Disease	xanthinuria (implicated_via_orthology)	AOX1 XDH	7.82e-06	2	83	2	DOID:0060236 (implicated_via_orthology)
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNB FLNC	2.34e-05	3	83	2	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNB FLNC	2.34e-05	3	83	2	DOID:0111190 (implicated_via_orthology)
Disease	type 2 diabetes mellitus (is_marker_for)	SELP ADM PIK3C2A FUCA1 F3	4.20e-05	136	83	5	DOID:9352 (is_marker_for)
Disease	autism spectrum disorder (implicated_via_orthology)	NDST3 EIF4E CHD9 CHD8 CHD6	7.13e-05	152	83	5	DOID:0060041 (implicated_via_orthology)
Disease	Autistic Disorder	ADM VWA8 EIF4E XDH CHD8 GABBR1	9.66e-05	261	83	6	C0004352
Disease	familial hyperlipidemia (is_marker_for)	BCHE F3	1.16e-04	6	83	2	DOID:1168 (is_marker_for)
Disease	heterogeneous nuclear ribonucleoproteins C1/C2 measurement	EHHADH BCHE	1.63e-04	7	83	2	EFO_0801675
Disease	Malignant neoplasm of breast	EHBP1 FLNB MYH9 FKTN TMPRSS6 XDH AFF1 BCHE F3 DNAH9 TOP2A	2.07e-04	1074	83	11	C0006142
Disease	diabetes mellitus (is_marker_for)	FUCA1 F3 ARPC3	2.12e-04	41	83	3	DOID:9351 (is_marker_for)
Disease	Muscular Dystrophy	FKTN BCHE	2.16e-04	8	83	2	C0026850
Disease	lifestyle measurement, depressive symptom measurement	NDST3 PLPPR4 VAT1L ADARB2	2.24e-04	105	83	4	EFO_0007006, EFO_0010724
Disease	epilepsy (is_implicated_in)	KCNB1 BCHE	2.78e-04	9	83	2	DOID:1826 (is_implicated_in)
Disease	Neuroblastoma	BCHE CHD6 TOP2A	3.18e-04	47	83	3	C0027819
Disease	transcription factor IIIb 90 kda subunit measurement	EHHADH BCHE	3.47e-04	10	83	2	EFO_0020778
Disease	PR domain zinc finger protein 1 measurement	EHHADH BCHE	4.23e-04	11	83	2	EFO_0801904
Disease	iron biomarker measurement, serum iron measurement	TMPRSS6 F3	5.07e-04	12	83	2	EFO_0004461, EFO_0006332
Disease	RAC-beta serine/threonine-protein kinase measurement	EHHADH BCHE	5.98e-04	13	83	2	EFO_0021989
Disease	T-cell surface glycoprotein CD3 epsilon chain measurement	SELP BCHE	5.98e-04	13	83	2	EFO_0802114
Disease	ankle injury	COL5A2 CHD9 F3	6.23e-04	59	83	3	EFO_1002021
Disease	iron biomarker measurement, transferrin saturation measurement	TMPRSS6 F3	6.96e-04	14	83	2	EFO_0004461, EFO_0006333
Disease	transferrin saturation measurement	TMPRSS6 F3	9.14e-04	16	83	2	EFO_0006333
Disease	congenital heart disease (implicated_via_orthology)	CHD9 CHD8 CHD6	9.84e-04	69	83	3	DOID:1682 (implicated_via_orthology)
Disease	serum hepcidin measurement	TMPRSS6 F3	1.16e-03	18	83	2	EFO_0004504
Disease	behavioural disinhibition measurement	EIF4E ACTN1 DNAH9	1.25e-03	75	83	3	EFO_0006946
Disease	laryngeal squamous cell carcinoma (is_marker_for)	XDH CDC73	1.30e-03	19	83	2	DOID:2876 (is_marker_for)
Disease	sensorineural hearing loss (implicated_via_orthology)	DNAH17 DNAH9	1.30e-03	19	83	2	DOID:10003 (implicated_via_orthology)
Disease	iron biomarker measurement, transferrin measurement	TMPRSS6 F3	1.44e-03	20	83	2	EFO_0004461, EFO_0006341
Disease	serum copper measurement	VWA3B VAT1L	1.59e-03	21	83	2	EFO_0005267
Disease	pars opercularis volume measurement	CWF19L2 DYNC1I1	1.74e-03	22	83	2	EFO_0010319
Disease	Kidney Failure	MYH9 GLA	1.74e-03	22	83	2	C0035078
Disease	energy expenditure	KCNB1 DYNC1I1	2.62e-03	27	83	2	EFO_0005109

Protein segments in the cluster

Peptide	Gene	Start	Entry
WAIKNEDIKPLSSKW	AGBL3	926	Q8NEM8
FKKPQSLTKWSDIWN	BCHE	71	P06276
ISLDDPNFWQKWAKK	CHD8	1366	Q9HCK8
DPAWEKQQRKTFTAW	ACTN1	26	P12814
WPTWRNPIFTKNTKI	C8orf44	66	Q96CB5
SWPKNVKTNYVVWGT	CDC73	31	Q6P1J9
WKSIKSILDWTSFNQ	GLA	236	P06280
KTKLLVSPQSWNGWL	ACSM4	186	P0C7M7
SFKTWWQKKPQMDLI	DNHD1	2786	Q96M86
LPSLQATKSWEKWSN	CCDC87	566	Q9NVE4
VASEFRKKWNKWALS	ADM	26	P35318
KNPKGTWKDWAQTAF	AOX1	1116	Q06278
EAWKKVWNIKITSTE	NDST3	436	O95803
NWKEAKLTWSFFKQS	RFT1	236	Q96AA3
VWKKLSWSVAPKNAL	ADARB2	116	Q9NS39
LVRSAAQWPWKKKNS	POGLUT1	191	Q8NBL1
VKISKWNDVSFWSIK	MDN1	3946	Q9NU22
KALKYKEQVETLWPW	DST	4956	Q03001
FEKWGWKKIATIQQT	GABBR1	301	Q9UBS5
NKGEKWFTNSWVLKR	LRRC53	686	A6NM62
SKAKELQTWEWIYGK	LIPT1	261	Q9Y234
WFFKNDKSKTWQANL	EIF4E	46	P06730
TLKSQWFSFTNPWTK	ARNTL2	446	Q8WYA1
DWTVKLWTTKHNKPL	DYNC1I1	511	O14576
SFDWTVKLWTTKNNK	DYNC1I2	501	Q13409
RKANKWSTPSGASWK	EHHADH	276	Q08426
DAPWKKIQQNTFTRW	FLNB	11	O75369
SQEKQTWWEKALYSP	KIAA0232	1281	Q92628
KILASAPNWKWVNLA	PIK3C2A	911	O00443
DQRKKALQFAQWWKP	CWF19L2	871	Q2TBE0
DAPWKKIQQNTFTRW	FLNC	31	Q14315
ASKPWRVQWEKNTTS	FUCA1	371	P04066
NYNKPWEPKWTKICS	MT-ATP8	46	P03928
CTKKWQPDKLVVVWT	EHBP1L1	31	Q8N3D4
WAAKKLVWVPSDKSG	MYH9	26	P35579
VTIKFKWWGLQSKVE	PITPNB	196	P48739
ILVKKTNDDWWQVKP	ARHGAP12	41	Q8IWW6
PDKVWWAKNSQAKTI	FAM24B	46	Q8N5W8
KPNKTWQQVFWFAIS	PGBD5	466	Q8N414
DFNDKWIASNWPSKI	DNAH1	906	Q9P2D7
SLDDPNFWQKWAKKA	CHD9	1416	Q3L8U1
TTWKKIWTSNGKTEP	KDM1B	111	Q8NB78
NHLSPNKWKWTKRTL	KCNB1	481	Q14721
SKWWINEFKTIKFPS	DNAH17	2376	Q9UFH2
EKVFDPQNDKPSKWW	ARPC3	146	O15145
SLDDPNFWQKWAKIA	CHD6	1016	Q8TD26
SNSKKVWYEWAVTAP	PRMT5	606	O14744
RKTWWASKSPDNKPV	COL5A2	1346	P05997
ANYGKTWKIPVKTWD	FKTN	421	O75072
CTKKWQPDKLVVVWT	EHBP1	31	Q8NDI1
KASGSKQQWTKILWS	LYST	2721	Q99698
KQQWTKILWSCKETF	LYST	2726	Q99698
KNNKTWTWVGTKKAL	SELP	96	P16109
HDLWKFNPVSFTWKK	KLHDC3	266	Q9BQ90
PEHKKATNKFWWENK	CENATAC	96	Q86UT8
WLSQWKKDHSPDQFK	MECR	311	Q9BV79
VWTFNLKTKENPSKW	DNAH9	4461	Q9NYC9
LTWKKAQETVPWNII	SLC13A3	416	Q8WWT9
GPWWKSLTNSRKKSK	PRR15	11	Q8IV56
LWKTWYPCAKTQKLV	USH2A	3146	O75445
WSVKPSTVVKCWQKA	TIGD6	361	Q17RP2
KVKKNLVPFFEAWGW	TCAF2	876	A6NFQ2
QKLSDPRLWQESFWK	SPATA31A7	396	Q8IWB4
TGIKWKKYVWQGPTS	MED13	26	Q9UHV7
WWESKEEKAKPFQNA	SETD1A	826	O15047
PDLNTVVWVWQSLKK	URB1	506	O60287
NKWQLDNWLTKVSQP	AFF1	511	P51825
WSIFPEWLKTRNAQK	CMBL	91	Q96DG6
KLAKWVAIQSVSAWP	CNDP2	21	Q96KP4
NEKVWKPSSRKWSSK	LINC01619	11	G3V211
QKLSDPRLWQESFWK	SPATA31A3	396	Q5VYP0
SWKWKAPEKGSLRQT	PLPPR4	646	Q7Z2D5
LEKKWQSVEPLTGWK	TMX4	136	Q9H1E5
QKLSDPRLWQESFWK	SPATA31A1	396	Q5TZJ5
TAKEWTFPEAKWNTT	SLC35A5	206	Q9BS91
QKLSDPRLWQESFWK	SPATA31A5	396	Q5VU36
WNLTNIKRWAASPKS	TLN1	351	Q9Y490
KKKTNLVWDEVSGQW	RRS1	126	Q15050
KKKNPSGSWEDWVTA	XDH	1106	P47989
FAKSWWQVEKVNPIK	VAT1L	291	Q9HCJ6
WKSTNFKTILEWEPK	F3	46	P13726
WSNPLKVWKINASFK	THUMPD3	126	Q9BV44
EEWKSSTPNHKKWKV	TOP2A	596	P11388
KPMWSQLFKDVNWTA	ZBED9	1086	Q6R2W3
DTWDSKTWLQKYGLK	VWA3B	386	Q502W6
IVLWNADTGTKLWKK	WDR11	141	Q9BZH6
KFTSKKPFWWNKEEA	VWA8	1211	A3KMH1
KVWQNSRWPGEVSFK	TMPRSS6	636	Q8IU80
WQKLIVWKFPPSKDT	ZW10	181	O43264
TFWNLTSIGKKWKDQ	ZNF439	51	Q8NDP4
ISSWLAWYQQKPEKA	IGKV1D-16	51	P01601