Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmetalloendopeptidase activity

ADAMTS18 ADAM8 ADAM20 ADAM9

1.20e-05120244GO:0004222
GeneOntologyMolecularFunctionmetallopeptidase activity

ADAMTS18 ADAM8 ADAM20 ADAM9

8.87e-05200244GO:0008237
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC39A10 SLC4A4

1.07e-0413242GO:0140410
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC39A10 SLC4A4

6.72e-0432242GO:0015106
GeneOntologyMolecularFunctionintegrin binding

ADAM8 ADAM20 ADAM9

1.17e-03175243GO:0005178
GeneOntologyMolecularFunctionendopeptidase activity

ADAMTS18 ADAM8 ADAM20 ADAM9

1.60e-03430244GO:0004175
GeneOntologyMolecularFunctionextracellular matrix binding

ADAM9 VEGFA

3.45e-0373242GO:0050840
GeneOntologyMolecularFunctionpeptidase activity

ADAMTS18 ADAM8 ADAM20 ADAM9

7.19e-03654244GO:0008233
GeneOntologyBiologicalProcesscell-cell adhesion

ADAMTS18 DCC ADAM8 IL4I1 PCDH9 ADAM9 PTK7 VEGFA

1.87e-051077248GO:0098609
GeneOntologyBiologicalProcessmesenchyme development

SLC39A10 ADAM8 PTK7 ZIC3 VEGFA

5.95e-05372245GO:0060485
GeneOntologyCellularComponentcell-cell junction

CDC42BPA CDC42BPB PCDH9 PTK7 VEGFA

4.83e-04591245GO:0005911
GeneOntologyCellularComponentanchoring junction

CDC42BPA CDC42BPB PCDH9 ADAM9 PTK7 VEGFA

6.65e-04976246GO:0070161
GeneOntologyCellularComponentcell surface

DCC SLC4A4 ADAM8 ADAM20 ADAM9 VEGFA

1.31e-031111246GO:0009986
DomainPeptidase_M12B_N

ADAMTS18 ADAM8 ADAM20 ADAM9

1.99e-0739254IPR002870
DomainPep_M12B_propep

ADAMTS18 ADAM8 ADAM20 ADAM9

1.99e-0739254PF01562
DomainDISINTEGRIN_1

ADAMTS18 ADAM8 ADAM20 ADAM9

2.21e-0740254PS00427
DomainADAM_MEPRO

ADAMTS18 ADAM8 ADAM20 ADAM9

2.21e-0740254PS50215
DomainDISINTEGRIN_2

ADAMTS18 ADAM8 ADAM20 ADAM9

2.21e-0740254PS50214
DomainReprolysin

ADAMTS18 ADAM8 ADAM20 ADAM9

2.21e-0740254PF01421
DomainPeptidase_M12B

ADAMTS18 ADAM8 ADAM20 ADAM9

2.21e-0740254IPR001590
DomainDisintegrin_dom

ADAMTS18 ADAM8 ADAM20 ADAM9

2.44e-0741254IPR001762
DomainDisintegrin_CS

ADAM8 ADAM20 ADAM9

1.17e-0616253IPR018358
DomainADAM_CR

ADAM8 ADAM20 ADAM9

1.71e-0618253PF08516
DomainKELK

CDC42BPA CDC42BPB

1.72e-062252PF15796
DomainKELK

CDC42BPA CDC42BPB

1.72e-062252IPR031597
Domain-

ADAM8 ADAM20 ADAM9

2.38e-06202534.10.70.10
DomainDISIN

ADAM8 ADAM20 ADAM9

2.77e-0621253SM00050
DomainDisintegrin

ADAM8 ADAM20 ADAM9

2.77e-0621253PF00200
DomainMetalloPept_cat_dom

ADAMTS18 ADAM8 ADAM20 ADAM9

3.87e-0681254IPR024079
Domain-

ADAMTS18 ADAM8 ADAM20 ADAM9

3.87e-06812543.40.390.10
DomainADAM_Cys-rich

ADAM8 ADAM20 ADAM9

6.07e-0627253IPR006586
DomainACR

ADAM8 ADAM20 ADAM9

6.07e-0627253SM00608
DomainZINC_PROTEASE

ADAMTS18 ADAM8 ADAM20 ADAM9

8.28e-0698254PS00142
DomainMyotonic_dystrophy_kinase_coil

CDC42BPA CDC42BPB

1.03e-054252IPR014930
DomainMyotonic_dystrophy_kinase_coil

CDC42BPA CDC42BPB

1.03e-054252PD011252
DomainDMPK_coil

CDC42BPA CDC42BPB

1.03e-054252PF08826
DomainEGF_extracell

ADAM8 LRP1B ADAM9

6.89e-0560253IPR013111
DomainEGF_2

ADAM8 LRP1B ADAM9

6.89e-0560253PF07974
DomainCNH

CDC42BPA CDC42BPB

1.55e-0414252SM00036
DomainCNH

CDC42BPA CDC42BPB

1.79e-0415252PS50219
DomainCNH_dom

CDC42BPA CDC42BPB

1.79e-0415252IPR001180
DomainCNH

CDC42BPA CDC42BPB

1.79e-0415252PF00780
DomainPBD

CDC42BPA CDC42BPB

2.04e-0416252SM00285
DomainEGF_3

ADAM8 LRP1B ADAM20 ADAM9

2.51e-04235254PS50026
DomainEGF-like_dom

ADAM8 LRP1B ADAM20 ADAM9

3.13e-04249254IPR000742
DomainCRIB

CDC42BPA CDC42BPB

3.22e-0420252PS50108
DomainEGF_1

ADAM8 LRP1B ADAM20 ADAM9

3.43e-04255254PS00022
DomainCRIB_dom

CDC42BPA CDC42BPB

3.56e-0421252IPR000095
DomainEGF-like_CS

ADAM8 LRP1B ADAM20 ADAM9

3.74e-04261254IPR013032
DomainEGF_2

ADAM8 LRP1B ADAM20 ADAM9

3.96e-04265254PS01186
DomainPkinase_C

CDC42BPA CDC42BPB

1.11e-0337252IPR017892
DomainCYSTEINE_SWITCH

ADAMTS18 ADAM20

1.37e-0341252PS00546
DomainPkinase_C

CDC42BPA CDC42BPB

1.43e-0342252PF00433
DomainPept_M10_metallopeptidase

ADAMTS18 ADAM20

1.50e-0343252IPR001818
DomainAGC-kinase_C

CDC42BPA CDC42BPB

2.53e-0356252IPR000961
DomainAGC_KINASE_CTER

CDC42BPA CDC42BPB

2.53e-0356252PS51285
DomainS_TK_X

CDC42BPA CDC42BPB

2.53e-0356252SM00133
DomainC1_1

CDC42BPA CDC42BPB

2.62e-0357252PF00130
DomainZF_DAG_PE_1

CDC42BPA CDC42BPB

3.30e-0364252PS00479
DomainZF_DAG_PE_2

CDC42BPA CDC42BPB

3.30e-0364252PS50081
DomainC1

CDC42BPA CDC42BPB

3.40e-0365252SM00109
DomainPE/DAG-bd

CDC42BPA CDC42BPB

3.50e-0366252IPR002219
DomainEGF

ADAM8 LRP1B ADAM9

3.69e-03235253SM00181
Pubmed

Cloning and chromosomal localization of human Cdc42-binding protein kinase beta.

CDC42BPA CDC42BPB

4.96e-07225210198171
Pubmed

A murine model for retinopathy of prematurity identifies endothelial cell proliferation as a potential mechanism for plus disease.

ADAM8 ADAM9

4.96e-07225223833070
Pubmed

Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta.

CDC42BPA CDC42BPB

4.96e-07225218263588
Pubmed

Netrin-1 induces apoptosis in human cervical tumor cells via the TAp73alpha tumor suppressor.

DCC TP73

1.49e-06325218922894
Pubmed

miR-126-3p down-regulation contributes to dabrafenib acquired resistance in melanoma by up-regulating ADAM9 and VEGF-A.

ADAM9 VEGFA

1.49e-06325231227006
Pubmed

Possible Role of Netrin-1/Deleted in Colorectal Cancer/Vascular Endothelial Growth Factor Signaling Pathway in the Pathogenesis of Placenta Accreta Spectrum: A Case-control Study.

DCC VEGFA

1.49e-06325238289148
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

CDC42BPA SLC39A10 CDC42BPB ADAM9 PTK7 BICD1

2.54e-0656925630639242
Pubmed

Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals.

LRP1B VEGFA

2.97e-06425221953277
Pubmed

A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow.

CDC42BPA CDC42BPB

2.97e-06425218854160
Pubmed

Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization.

CDC42BPA CDC42BPB

2.97e-0642529418861
Pubmed

ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23.

ADAM8 ADAM9

4.95e-06525217072319
Pubmed

The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs.

ADAM8 ADAM9

4.95e-06525212135759
Pubmed

Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics.

CDC42BPA CDC42BPB

7.43e-06625225107909
Pubmed

Shedding of collagen XVII/BP180 in skin depends on both ADAM10 and ADAM9.

ADAM8 ADAM9

7.43e-06625219574220
Pubmed

Abundance of ADAM-8, -9, -10, -12, -15 and -17 and ADAMTS-1 in mouse uterus during the oestrous cycle.

ADAM8 ADAM9

1.04e-05725215907280
Pubmed

MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion.

CDC42BPA CDC42BPB

1.04e-05725229162624
Pubmed

Different ADAMs have distinct influences on Kit ligand processing: phorbol-ester-stimulated ectodomain shedding of Kitl1 by ADAM17 is reduced by ADAM19.

ADAM8 ADAM9

1.39e-05825217344430
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

CDC42BPA SLC39A10 PCDH9 ADAM9 PTK7

1.82e-0546725530194290
Pubmed

Understanding the development of oral epithelial organs through single cell transcriptomic analysis.

LGR6 SLC4A4 PCDH9

1.97e-057325335831953
Pubmed

PAK is regulated by PI3K, PIX, CDC42, and PP2Calpha and mediates focal adhesion turnover in the hyperosmotic stress-induced p38 pathway.

CDC42BPA CDC42BPB

4.49e-051425218586681
Pubmed

CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase.

DCC VEGFA

5.18e-051525226503042
Pubmed

Phenotypic analysis of mice completely lacking netrin 1.

DCC VEGFA

5.18e-051525226395479
Pubmed

Ankrd17, an ubiquitously expressed ankyrin factor, is essential for the vascular integrity during embryogenesis.

ANKRD17 VEGFA

7.54e-051825219619540
Pubmed

ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.

ADAMTS18 VEGFA

7.54e-051825239040056
Pubmed

Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly.

TP73 ZIC3

1.14e-042225218448648
Pubmed

Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.

ADAM20 ADAM9

1.24e-042325230814516
Pubmed

Deletion of Stk40 impairs definitive erythropoiesis in the mouse fetal liver.

ADAM8 TP73

1.24e-042325228358362
Pubmed

Preferred SH3 domain partners of ADAM metalloproteases include shared and ADAM-specific SH3 interactions.

ADAM8 ADAM9

1.36e-042425225825872
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

CDC42BPA SLC39A10 CDC42BPB ADAM9

1.44e-0437725438117590
Pubmed

Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.

CDC42BPB BICD1

1.47e-042525212522145
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

CDC42BPA LRP1B CDC42BPB ADAM20 ADAM9

1.51e-0473025534857952
Pubmed

Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment.

GOLGA8A PTK7

1.72e-042725230516471
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

MSRA SLC39A10 DCC SLC4A4

1.89e-0440525438187761
Pubmed

Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set.

ADAMTS18 DCC VEGFA

1.93e-0415725312466305
Pubmed

γ-Linolenic acid in maternal milk drives cardiac metabolic maturation.

CPT1B VEGFA

2.13e-043025237225978
Pubmed

Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.

CPT1B TP73 VEGFA

2.84e-0417925319074885
Pubmed

A human MAP kinase interactome.

ANKRD17 CDC42BPA SLC4A4 CDC42BPB

3.77e-0448625420936779
Pubmed

PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression.

ADAM8 PCDH9

4.00e-044125221282332
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

ANKRD17 CDC42BPA CDC42BPB

4.04e-0420225333005030
Pubmed

Obesity and High-Fat Diet Induce Distinct Changes in Placental Gene Expression and Pregnancy Outcome.

CPT1B VEGFA

4.20e-044225229438518
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

SLC39A10 SLC4A4 PCDH9 ADAM9 BICD1

5.12e-0495225538569033
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MSRA ANKRD17 CDC42BPA CDC42BPB PTK7 BICD1

5.35e-04148925628611215
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ANKRD17 SLC4A4 GOLGA8A CDC42BPB ADAM9

5.40e-0496325528671696
Pubmed

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia.

ADAM8 VEGFA

5.48e-044825235247391
Pubmed

A screen for downstream effectors of Neurogenin2 in the embryonic neocortex.

DCC PCDH9

6.43e-045225215328020
Pubmed

Genome-wide atlas of gene expression in the adult mouse brain.

DCC SLC4A4

6.94e-045425217151600
InteractionPPM1A interactions

CDC42BPA CDC42BPB PCDH9 PTK7 BICD1

1.52e-06163255int:PPM1A
InteractionADAM20 interactions

ADAM20 ADAM9

8.85e-064252int:ADAM20
InteractionARL14 interactions

CDC42BPA SLC39A10 CDC42BPB PCDH9

1.33e-05119254int:ARL14
InteractionNRAS interactions

CDC42BPA SLC39A10 CDC42BPB PCDH9 ADAM9 PTK7 BICD1

1.63e-05699257int:NRAS
CytobandEnsembl 112 genes in cytogenetic band chr4q13

ANKRD17 SLC4A4

3.31e-03157252chr4q13
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM8 ADAM20 ADAM9

1.34e-062715347
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

DCC PTK7

7.67e-03161152593
GeneFamilyImmunoglobulin like domain containing

DCC PTK7

1.09e-02193152594
GeneFamilyAnkyrin repeat domain containing

ANKRD17 ESPNL

1.67e-02242152403
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LGR6 CPT1B ADAM8 LRP1B

1.98e-061632541e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IL4I1 CDC42BPB PCDH9 VEGFA

2.62e-06175254334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

IL4I1 CDC42BPB PCDH9 VEGFA

2.62e-06175254da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCellNeuronal-Excitatory-eD(FEZF2)-ABO---L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

LGR6 SLC4A4 LRP1B PTK7

4.46e-062002547b845aabfbdfe893acc9334a5707833761bed60b
ToppCellNeuronal-Excitatory-eD(FEZF2)-ABO-|Neuronal / cells hierarchy compared to all cells using T-Statistic

LGR6 SLC4A4 LRP1B PTK7

4.46e-06200254e3051dcf9b5c8e4dc71a8080b7a7aafea46f2b2b
ToppCellNeuronal-Excitatory-eD(FEZF2)-ABO|Neuronal / cells hierarchy compared to all cells using T-Statistic

LGR6 SLC4A4 LRP1B PTK7

4.46e-062002540638273fc0910f47fe7a0b6d9a8639b0e9976d13
ToppCellNeuronal-Excitatory-eD(FEZF2)-ABO--|Neuronal / cells hierarchy compared to all cells using T-Statistic

LGR6 SLC4A4 LRP1B PTK7

4.46e-062002541ce9599cc9d8158e8842ca56f35fa7809c234849
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|343B / Donor, Lineage, Cell class and subclass (all cells)

LGR6 CPT1B IL4I1

7.76e-051492532a7f71da51c85e04de2123164914122480e60d66
ToppCellHealthy_Control-Myeloid-Macrophages-FCN1_high|Healthy_Control / Condition, Lineage, Cell class and cell subclass

ADAM8 IL4I1 VEGFA

8.72e-05155253cd2ccb4632713b4def3a1064599b78207e2e44c0
ToppCellAT1-AT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

DCC PCDH9 VEGFA

8.72e-05155253010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCellBasal_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

LGR6 SLC4A4 LRP1B

8.72e-0515525330accc72a6a914ae0c4d52b373ea1c9a98efbf22
ToppCellBasal_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

LGR6 GOLGA8A LRP1B

9.58e-05160253b223cc47e68a29df4758c5ccf8f6dbffe2a6fa1d
ToppCelldroplet-Lung-30m-Hematologic-myeloid-neutrophil|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MSRA ADAM8 GOLGA8A

9.94e-051622539c9a63adb692651ea5a52cc77b02c5ce11d0ccea
ToppCelldroplet-Lung-30m-Hematologic-myeloid-neutrophil-neutrophil|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MSRA ADAM8 GOLGA8A

9.94e-051622531d29983b22f963b34e72cfd1eec328d2d7c4932f
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Cajal-Retzius|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

DCC TP73 ZIC3

1.01e-04163253c1484e4de8b10e2f5fb14a7c02b2a015ffe0305e
ToppCelldroplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM8 IL4I1 BICD1

1.03e-0416425378de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

IL4I1 PCDH9 VEGFA

1.07e-04166253773673a5d0430640439845b264740bfbbdad0cb2
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue

IL4I1 PCDH9 VEGFA

1.09e-041672533ae46c6363da76c8e1f5579e6027bf88ed637a44
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue

IL4I1 PCDH9 VEGFA

1.11e-04168253d02eba7ece17edcdd47fd6b784c93910ce61090f
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-ILC3|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GOLGA8A IL4I1 PCDH9

1.13e-04169253d4a0bd792bddfa34332d7dc432ce253f50d98c6f
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCC LRP1B TP73

1.13e-0416925312bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

IL4I1 PCDH9 VEGFA

1.15e-0417025397df5ffb328196c46568975d2d97722bcc753bf5
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS18 SLC4A4 LRP1B

1.15e-041702535570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCC LRP1B TP73

1.21e-0417325366f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCC LRP1B TP73

1.21e-04173253649b08a409095592cccf31883be69c754411280d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LGR6 SLC4A4 PTK7

1.25e-0417525390e29945aa861082c94bb4f331161adc3a6ef899
ToppCellwk_15-18-Hematologic-Myeloid-aDC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

C1orf167 ADAM8 IL4I1

1.25e-04175253c31178d7a5a19d7afd336c9ec0e5c493655a6aa4
ToppCellAT1_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

C1orf167 GOLGA8A VEGFA

1.27e-041762534a30bb771297b30926fb98e2b5ec0dbdc46feac7
ToppCell3'_v3-blood-Mast-Mast_cells|blood / Manually curated celltypes from each tissue

CDC42BPA ADAM8 PCDH9

1.27e-04176253b9da3deaf62622d47eb30b6be7548253eee95597
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LGR6 SLC4A4 PTK7

1.27e-04176253e4b21fd6a5e0c5950f27c3e1868318e48330ae5e
ToppCell368C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CDC42BPA CDC42BPB PCDH9

1.29e-04177253946803293a7955116c80f403e99e4093e798ca3f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LGR6 SLC4A4 PTK7

1.29e-04177253bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPT1B TP73 BICD1

1.34e-04179253a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellBAL-Control-Myeloid-MoAM-MoAM2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAM8 IL4I1 VEGFA

1.34e-041792532fca4117c58824562ec80c7713fe15689a28efb3
ToppCellBAL-Control-Myeloid-MoAM-MoAM2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAM8 IL4I1 VEGFA

1.34e-04179253898425fa81526a2e00fca7a25085229ff1f31069
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LGR6 SLC4A4 PTK7

1.34e-04179253f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCellBAL-Control-Myeloid-MoAM-MoAM2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ADAM8 IL4I1 VEGFA

1.36e-04180253dcec59d66995f701d816eaeea3ed1439a2f71b73
ToppCellBAL-Control-Myeloid-MoAM-MoAM2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ADAM8 IL4I1 VEGFA

1.36e-04180253f3d8329b7e754c1ed89b0f39b8cd9e2ae22f6725
ToppCellControl-Myeloid-MoAM2|Control / Disease group,lineage and cell class （2021.01.30）

ADAM8 IL4I1 VEGFA

1.36e-0418025338892483a6a5388765aec87f0119c0b9bb5c7cbd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MSRA DCC SLC4A4

1.38e-041812539542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MSRA DCC SLC4A4

1.38e-041812538f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellCTRL-Myeloid-cDC|Myeloid / Disease state, Lineage and Cell class

ADAM8 IL4I1 VEGFA

1.40e-04182253ee137574b8f0e684a4a7cb26226877c471cae433
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL4I1 ADAM9 VEGFA

1.43e-0418325336b194e366a14ebc4df187bf31c902be3797bfcc
ToppCellCOVID-19-B_cells-Plasma_cells|COVID-19 / group, cell type (main and fine annotations)

DCC TP73 BICD1

1.43e-04183253130c109f63a5e3c8f83cb96e32f4addf513b6415
ToppCellCTRL-Myeloid-cDC|CTRL / Disease state, Lineage and Cell class

ADAM8 IL4I1 VEGFA

1.43e-0418325320c4d16de7e090df3556a4458f783383a26871b6
ToppCellCOVID-19-B_cells|COVID-19 / group, cell type (main and fine annotations)

DCC TP73 BICD1

1.43e-041832532c016bb59f131a0e821853b085289a3583f0a729
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL4I1 ADAM9 VEGFA

1.43e-04183253745271bfe15e94a58157cd97d771e610f964341b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCC SLC4A4 LRP1B

1.45e-04184253ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCC SLC4A4 LRP1B

1.45e-041842532cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCC SLC4A4 LRP1B

1.45e-041842532b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B PCDH9 PTK7

1.45e-04184253d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS18 LGR6 SLC4A4

1.45e-041842536b0c110d8930df99043c3b99cf4d873985126960
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ADAM8 IL4I1 VEGFA

1.45e-041842530a26bcc6610f756939e32a4d6dfeebcbf3a1db86
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS18 LGR6 SLC4A4

1.45e-0418425335928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS18 LGR6 SLC4A4

1.45e-04184253f6148e9591e8845cc62668e49fd52755257cdc7e
ToppCell(00)_Basal-(4)_1wkpi|(00)_Basal / shred by cell type and Timepoint

LGR6 TP73 VEGFA

1.47e-04185253bf82ba905e5eee1c39a2731702071d3de10a78b8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A4 CDC42BPB ADAM9

1.47e-04185253a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAM8 IL4I1 VEGFA

1.47e-04185253fec16a5e527fdef32d25957451b6e8ee9796cafd
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADAMTS18 LRP1B PCDH9

1.50e-041862538915436d09775f2828a7678af203b1082b36e21c
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADAM8 IL4I1 VEGFA

1.50e-041862530dce13e15c3bf32610bf2dad31253b52a39cff87
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MSRA DCC SLC4A4

1.50e-041862538287146f0ba415ea04475588117d4668ae00f75c
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCC PCDH9 ADAM9

1.52e-04187253ac8e092b37e042975e2ee057d3f7c6821e58e8b5
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCC PCDH9 ADAM9

1.52e-04187253d591a3c216997663ab77710fed0d230ffc37e41a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LGR6 SLC4A4 PCDH9

1.52e-04187253b426a67b5669019115b58295ce7d304beeb75825
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MSRA DCC SLC4A4

1.52e-0418725371eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCC PCDH9 ADAM9

1.52e-04187253d1dc8c9a2c2cd10c640257161a75e7730ec5bb41
ToppCellAT1-AT2_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

C1orf167 GOLGA8A VEGFA

1.54e-04188253be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B PCDH9 BICD1

1.54e-041882534154f4787483c7e076e87a187733a9f666742c3d
ToppCellCOVID_vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_vent / Disease condition, Lineage, Cell class and subclass

CDC42BPA PCDH9 PTK7

1.57e-041892532157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD17 CDC42BPA PCDH9

1.57e-04189253830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B PCDH9 PTK7

1.57e-04189253e059be2965cca70ff5576df055d0af1775b76e00
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DCC LRP1B PCDH9

1.59e-041902537986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DCC LRP1B PCDH9

1.62e-04191253fa380a8752de158974b2ae5e741573439719cc0d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MSRA DCC SLC4A4

1.62e-041912533c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MSRA DCC SLC4A4

1.62e-041912531c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellCOPD-Myeloid-cDC2|COPD / Disease state, Lineage and Cell class

ADAM8 IL4I1 VEGFA

1.62e-041912532af6e4a6bd1f2193ece2131c3b7d976dd23a6966
ToppCellILEUM-non-inflamed-(6)_ILC3|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IL4I1 PCDH9 VEGFA

1.62e-041912536eaf72b41084404bee0db04e4605db745a74995f
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IL4I1 LRP1B BICD1

1.64e-0419225381baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCellBAL-Control-Myeloid-MoAM-MoAM3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAM8 IL4I1 VEGFA

1.67e-04193253837c61408462c519912ecf3b83fdc72cd85fe88f
ToppCellControl-Myeloid-MoAM3|Control / Disease group,lineage and cell class （2021.01.30）

ADAM8 IL4I1 VEGFA

1.67e-0419325397d2f12be43fc26efa84ac4c6119132928a123de
ToppCellBAL-Control-Myeloid-MoAM-MoAM3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAM8 IL4I1 VEGFA

1.67e-04193253e4ca3a3c2704cdc52e6ac3f25f14debf74226c29
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ADAM8 IL4I1 VEGFA

1.67e-04193253704378de39e1b6f108ab5b0ecbd594d414ec8ae4
ToppCell10x5'-Lung-Myeloid_Dendritic-DC2|Lung / Manually curated celltypes from each tissue

ADAM8 IL4I1 VEGFA

1.67e-04193253c97f9b13057f803df63c696c6175ef8e0aba6fa7
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IL4I1 LRP1B BICD1

1.67e-041932537261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCellBAL-Control-Myeloid-MoAM-MoAM3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ADAM8 IL4I1 VEGFA

1.67e-04193253e54f8b6381b5a96758cff41ab12d6f60cfca29a9
ToppCellBAL-Control-Myeloid-MoAM-MoAM3|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ADAM8 IL4I1 VEGFA

1.67e-04193253d81840e1322507552b7726bf7828309375162324
ToppCellControl-Myeloid-Macrophage|Myeloid / Disease state, Lineage and Cell class

ADAM8 ADAM9 VEGFA

1.67e-041932532a6d531abd34df20941cf3dac4fdfb1621a1bde6
ToppCellControl-Myeloid-MoAM5,_CCL3L1|Control / Condition, Lineage and Cell class

ADAM8 IL4I1 VEGFA

1.69e-04194253a1dd264822de83a0ffaf89ca4707c6a76809359e
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM8 IL4I1 VEGFA

1.69e-041942533ef9e88e66f2f2ae95dcc834ea605c40c60783fc
ToppCellControl-Myeloid-Migratory_DC|Control / Condition, Lineage and Cell class

ADAM8 IL4I1 VEGFA

1.69e-04194253374076e60dcee83eb1814aa6b55b77668909f40b
ToppCellBAL-Control-Myeloid-MoAM|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAM8 IL4I1 VEGFA

1.69e-04194253125bf2909cf89133693bc7b865ca08955cf67a2e
ToppCellCTRL-Myeloid-Monocyte_Macrophage|Myeloid / Disease state, Lineage and Cell class

ADAM8 IL4I1 VEGFA

1.69e-0419425373459ee062ae1f1a3bb9719dc0b89aae10600e22
ToppCellControl-Myeloid-MoAM5,_CCL3L1|Myeloid / Condition, Lineage and Cell class

ADAM8 IL4I1 VEGFA

1.69e-0419425396400477d130b2403ed81c229e4e4182cc2cdc14
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAM8 IL4I1 VEGFA

1.69e-0419425336f8ae4f2b3bf802f6ff0e9fc79e7f170f96ae8b
ToppCellBAL-Control-Myeloid-MoAM|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ADAM8 IL4I1 VEGFA

1.69e-04194253a4523adbbd25c314809eed3414d66a5b323446e5
ToppCellCTRL-Myeloid-Monocyte_Macrophage|CTRL / Disease state, Lineage and Cell class

ADAM8 IL4I1 VEGFA

1.69e-04194253927480f56cccd3940b689f3c40ee132fe3e63745
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DCC PCDH9 ADAM9

1.69e-04194253a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DCC LRP1B PCDH9

1.69e-0419425385e00861c5068a27d0cf0ae677f420c8245baa9a
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

C1orf167 GOLGA8A VEGFA

1.72e-0419525368f4cc84b5ae7f4159b780c78e4b66c94211779a
ToppCellnormal_Lung-Epithelial_cells-AT1|normal_Lung / Location, Cell class and cell subclass

C1orf167 GOLGA8A VEGFA

1.72e-04195253569d1ebc5a5aa110a2430b096755ae35354040c4
DrugEstradiol-17 beta [50-28-2]; Down 200; 14.6uM; PC3; HT_HG-U133A

CDC42BPA SLC4A4 NMT1 PTK7 VEGFA

1.78e-061902556718_DN
DrugOxaprozin [21256-18-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A

CDC42BPA CPT1B ADAM8 ZIC3 VEGFA

2.18e-061982553876_DN
Druggadodiamide

SLC39A10 IL4I1 VEGFA

1.96e-0548253ctd:C064925
Drughydroxyephedrine

ADAM8 ZIC3

5.18e-0510252CID000009701
Drug2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one

TP73 VEGFA

5.18e-0510252ctd:C451219
DrugDicyclomine hydrochloride [67-92-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A

CDC42BPA SLC4A4 BICD1 VEGFA

5.18e-051902541483_UP
Drug17-AAG; Down 200; 1uM; PC3; HT_HG-U133A

CDC42BPA CPT1B ADAM8 VEGFA

5.40e-051922544449_DN
DrugBenfluorex hydrochloride [23642-66-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A

CDC42BPA SLC4A4 CPT1B VEGFA

5.62e-051942542621_UP
Drugradicicol, diheterospora chlamydosporia; Down 200; 0.1uM; PC3; HT_HG-U133A

CDC42BPA ADAM8 BICD1 VEGFA

5.62e-051942541219_DN
DrugRemoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; HL60; HT_HG-U133A

CDC42BPA ADAM8 ADAM20 PTK7

5.73e-051952543124_UP
Drug2-propylpentanoic acid; Down 200; 1000uM; PC3; HT_HG-U133A

CDC42BPA CPT1B ADAM8 BICD1

5.73e-051952544433_DN
DrugDicumarol [66-76-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A

CDC42BPA SLC4A4 PCDH9 BICD1

5.96e-051972543848_DN
DrugChlortetracycline hydrochloride [64-72-2]; Down 200; 7.8uM; MCF7; HT_HG-U133A

CDC42BPA SLC4A4 CPT1B VEGFA

5.96e-051972541541_DN
DrugPentolinium bitartrate [52-62-0]; Down 200; 7.4uM; PC3; HT_HG-U133A

SLC4A4 CPT1B PCDH9 BICD1

6.08e-051982543676_DN
DrugScopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; MCF7; HT_HG-U133A

CDC42BPA PCDH9 ZIC3 VEGFA

6.20e-051992545436_UP
DrugTrimethoprim [738-70-5]; Down 200; 13.8uM; PC3; HT_HG-U133A

CDC42BPA SLC4A4 CPT1B BICD1

6.20e-051992543678_DN
Drugestradiol, USP; Down 200; 0.01uM; PC3; HT_HG-U133A

CDC42BPA SLC4A4 PTK7 BICD1

6.20e-051992541241_DN
Drugnordihydroguaiaretic acid; Up 200; 1uM; HL60; HT_HG-U133A

SLC4A4 ADAM8 ADAM20 BICD1

6.20e-051992546182_UP
DrugOrlistat; Down 200; 10uM; MCF7; HT_HG-U133A

SLC4A4 ADAM8 BICD1 VEGFA

6.32e-052002546415_DN
DrugPA-e

MSRA SLC4A4 VEGFA

6.36e-0571253CID000007994
DrugAC1L9L1A

SLC4A4 ADAM8

1.04e-0414252CID000447615
Drugsodium ampicillin

MSRA SLC39A10 ADAM8

1.38e-0492253CID000002173
Diseasecervix uteri carcinoma in situ (is_marker_for)

ADAM9 TP73 VEGFA

6.03e-0642253DOID:8991 (is_marker_for)
Diseasecerebral cavernous malformation (implicated_via_orthology)

CDC42BPA CDC42BPB

3.77e-0511252DOID:0060669 (implicated_via_orthology)
DiseaseAdenocarcinoma of large intestine

DCC CDC42BPB PTK7

7.29e-0596253C1319315
Diseasecolorectal cancer (is_implicated_in)

DCC LRP1B TP73

1.45e-04121253DOID:9256 (is_implicated_in)
Diseasemood instability measurement

MSRA DCC LRP1B

1.71e-04128253EFO_0008475
Diseasesmoking behavior

MSRA CDC42BPA DCC PCDH9

1.83e-04341254EFO_0004318
DiseaseDNA methylation

MSRA ADAMTS18 DCC NMT1 LRP1B

1.96e-04656255GO_0006306
Diseaseazoospermia (implicated_via_orthology)

CDC42BPA CDC42BPB

2.39e-0427252DOID:14227 (implicated_via_orthology)
Diseaselevel of Sphingomyelin (d42:2) in blood serum

ANKRD17 SLC4A4

2.76e-0429252OBA_2045183
Diseaseposterior urethral valve

PCDH9 PTK7

2.76e-0429252MONDO_0019640
Diseaselevel of Sphingomyelin (d38:1) in blood serum

ANKRD17 SLC4A4

2.95e-0430252OBA_2045180
Diseaselevel of Sphingomyelin (d40:1) in blood serum

ANKRD17 SLC4A4

3.37e-0432252OBA_2045182
Diseaseinsomnia measurement

MSRA DCC NMT1 PCDH9

4.94e-04443254EFO_0007876
Diseasepost-traumatic stress disorder

LGR6 DCC SLC4A4

6.51e-04202253EFO_0001358
Diseasevascular endothelial growth factor measurement

PTK7 VEGFA

1.03e-0356252EFO_0004762
Diseasepancreatic ductal carcinoma (is_marker_for)

ADAM8 ADAM9

1.22e-0361252DOID:3587 (is_marker_for)
Diseasehypertension, white matter hyperintensity measurement

DCC NMT1

1.26e-0362252EFO_0000537, EFO_0005665
Diseaseaggressive behaviour measurement, ADHD symptom measurement

MSRA DCC

1.52e-0368252EFO_0007826, EFO_0007860
Diseasepulse pressure measurement, alcohol drinking

MSRA C1orf167

1.61e-0370252EFO_0004329, EFO_0005763
Diseaselung cancer (is_implicated_in)

LRP1B TP73

1.79e-0374252DOID:1324 (is_implicated_in)
Diseaseneuroimaging measurement

ADAMTS18 CDC42BPA DCC PTK7 BICD1

1.79e-031069255EFO_0004346
Diseasehepatocellular carcinoma (is_marker_for)

LRP1B TP73 VEGFA

2.05e-03301253DOID:684 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
PGMHHEAQQQAGESA

C1orf167

1116

Q5SNV9
GSEPNNDDKMNGHIH

BICD1

276

Q96G01
GHELGHNLGMQHDTQ

ADAM20

341

O43506
MGHNLGMDHDENVQG

ADAM8

336

P78325
EDHNENGHTPLMEAG

ANKRD17

361

O75179
HESGHNFGMIHDGEG

ADAMTS18

436

Q8TE60
HDPTQGMRQGNDHGT

MSRA

141

Q9UJ68
HPDKMANDQGRHGDG

DCC

1046

P43146
GGTPLHDAAENGQME

ESPNL

271

Q6ZVH7
DHDHNDGGLLDPGFM

LRP1B

4501

Q9NZR2
LPQMMEGNGNGHEHC

NMT1

16

P30419
EGNHFGNPQPSMDGE

LGR6

921

Q9HBX8
NEGHFNNGSHMTDIP

PCDH9

1201

Q9HC56
PTNFNHVAHMGPGDG

CDC42BPB

1586

Q9Y5S2
GMLNNHGHAVPANGE

TP73

451

O15350
AHELGHNLGMNHDDG

ADAM9

346

Q13443
PEMLHGDGDNEEHGF

SLC39A10

781

Q9ULF5
MFDPEQHPNHLGAGG

CPT1B

696

Q92523
SPEGHASDMEGQGHV

IL4I1

516

Q96RQ9
GEMQDHQEHPGLGSN

GOLGA8A

601

A7E2F4
NFNHIAHMGPGDGIQ

CDC42BPA

1576

Q5VT25
HVTMEHVGGPEQNNH

ZIC3

281

O60481
ENVQMNGDTPHDGGH

SLC4A4

411

Q9Y6R1
AAPMAEGGGQNHHEV

VEGFA

26

P15692
THGEMPHGGQADDEV

PTK7

1001

Q13308