Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH3 MYO1A MYO5A MYO5B MYO1H

5.70e-06381365GO:0000146
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DDX47 MYH3 MYO5B DYNC2H1 RAB40A ABCA10 ABCA9 GFM2 RHEB HELB DDX46 SLFN13 RHOBTB2 MCM9 RAB40AL ATP11A RAB40B

2.12e-0577513617GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

DDX47 MYH3 MYO5B DYNC2H1 RAB40A ABCA10 ABCA9 GFM2 RHEB HELB DDX46 SLFN13 RHOBTB2 MCM9 RAB40AL ATP11A RAB40B

5.72e-0583913617GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

DDX47 MYH3 MYO5B DYNC2H1 RAB40A ABCA10 ABCA9 GFM2 RHEB HELB DDX46 SLFN13 RHOBTB2 MCM9 RAB40AL ATP11A RAB40B

5.81e-0584013617GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

DDX47 MYH3 MYO5B DYNC2H1 RAB40A ABCA10 ABCA9 GFM2 RHEB HELB DDX46 SLFN13 RHOBTB2 MCM9 RAB40AL ATP11A RAB40B

5.81e-0584013617GO:0016818
GeneOntologyMolecularFunctionATP-dependent activity

DDX47 MYH3 MYO1A MYO5A MYO5B DYNC2H1 MYO1H ABCA10 ABCA9 HELB DDX46 SLFN13 MCM9 ATP11A

7.88e-0561413614GO:0140657
GeneOntologyMolecularFunctionpotassium:proton antiporter activity

SLC9C2 SLC9C1 SLC9A3

1.06e-04141363GO:0015386
GeneOntologyMolecularFunctioncoumarin 7-hydroxylase activity

CYP2A7 CYP2A13

1.38e-0431362GO:0008389
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH3 MYO1A MYO5A MYO5B DYNC2H1 MYO1H

1.58e-041181366GO:0003774
GeneOntologyMolecularFunctionsodium:proton antiporter activity

SLC9C2 SLC9C1 SLC9A3

1.62e-04161363GO:0015385
GeneOntologyMolecularFunctionATP hydrolysis activity

DDX47 MYH3 MYO5B DYNC2H1 ABCA10 ABCA9 HELB DDX46 SLFN13 MCM9 ATP11A

2.21e-0444113611GO:0016887
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1F CACNA1S KCNA1 KCNT2 CLCN5 KCNA10 SCN2A

2.53e-041821367GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1F CACNA1S KCNA1 KCNT2 CLCN5 KCNA10 SCN2A

2.70e-041841367GO:0022832
GeneOntologyMolecularFunctionsolute:potassium antiporter activity

SLC9C2 SLC9C1 SLC9A3

2.76e-04191363GO:0022821
GeneOntologyMolecularFunction3'-5' exonuclease activity

EXD1 DIS3L POLE CNOT6L

7.95e-04611364GO:0008408
GeneOntologyMolecularFunctionmetal cation:proton antiporter activity

SLC9C2 SLC9C1 SLC9A3

8.02e-04271363GO:0051139
GeneOntologyMolecularFunctionactin filament binding

MYH3 MYO1A MYO5A MYO5B MYO1H TULP1 SPTBN5

9.45e-042271367GO:0051015
GeneOntologyMolecularFunctionchannel activity

CACNA1F CACNA1S PKD1L1 ANO5 RHAG SLC9C1 KCNA1 KCNT2 CLCN5 KCNA10 SCN2A

9.46e-0452513611GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1F CACNA1S PKD1L1 ANO5 RHAG SLC9C1 KCNA1 KCNT2 CLCN5 KCNA10 SCN2A

9.61e-0452613611GO:0022803
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC9C2 SLC9C1 SLC9A3 KCNA1 KCNT2 KCNA10

1.00e-031671366GO:0015079
GeneOntologyMolecularFunctioncalmodulin binding

CACNA1S MYH3 MYO1A MYO5A MYO5B SCN2A UNC13C

1.02e-032301367GO:0005516
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1F CACNA1S PKD1L1 ANO5 SLC9C1 KCNA1 KCNT2 CLCN5 KCNA10 SCN2A

1.21e-0345913610GO:0005216
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1F CACNA1S PKD1L1 SLC9C2 SLC9C1 SLC9A3 KCNA1 KCNT2 KCNA10 SCN2A

1.33e-0346513610GO:0046873
GeneOntologyMolecularFunctionsteroid hydroxylase activity

CYP2A7 CYP2A13 CYP2R1

1.58e-03341363GO:0008395
GeneOntologyMolecularFunctioncalcium ion binding

FAT4 CALR3 MYL1 MYO5A PCDHGA4 FAT3 CDH23 DUOX2 S100A2 BMP1 TLL2 UNC13C RAB11FIP3

1.83e-0374913613GO:0005509
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1F CACNA1S PKD1L1 ANO5 SLC9C2 RHAG SLC9C1 SLC9A3 KCNA1 KCNT2 CLCN5 KCNA10 SCN2A

2.04e-0375813613GO:0015318
GeneOntologyMolecularFunctiongated channel activity

CACNA1F CACNA1S ANO5 KCNA1 KCNT2 CLCN5 KCNA10 SCN2A

2.08e-033341368GO:0022836
GeneOntologyMolecularFunctionlipid transporter activity

ANO5 ABCA10 ABCA9 FABP2 SLCO1A2 ATP11A

2.27e-031961366GO:0005319
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1F CACNA1S PKD1L1 ANO5 SLC9C2 ABCA10 ABCA9 RHAG FABP2 SLC9C1 SLC9A3 KCNA1 KCNT2 CLCN5 KCNA10 SLCO1A2 SCN2A

2.76e-03118013617GO:0022857
GeneOntologyMolecularFunctiontransporter activity

CACNA1F CACNA1S PKD1L1 ANO5 SLC9C2 ABCA10 ABCA9 RHAG FABP2 SLC9C1 SLC9A3 KCNA1 KCNT2 CLCN5 KCNA10 SLCO1A2 SCN2A ATP11A

2.89e-03128913618GO:0005215
GeneOntologyBiologicalProcessactin filament-based movement

MYH3 MYL1 MYO1A MYO5A MYO5B MYO1H SCN2A PARVA

7.22e-061531348GO:0030048
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase I

MACROH2A1 ACTR6 MACROH2A2

4.26e-05111343GO:0016479
GeneOntologyCellularComponentmyosin complex

MYH3 MYL1 MYO1A MYO5A MYO5B MYO1H

2.21e-06591356GO:0016459
GeneOntologyCellularComponentapical cortex

MYO5B FABP2 SPTBN5

3.06e-05101353GO:0045179
GeneOntologyCellularComponentnon-motile cilium

CACNA1F MYO5A PKD1L1 CDH23 TULP1 SPTBN5 GUCY2D PKHD1

4.15e-051961358GO:0097730
GeneOntologyCellularComponentapical part of cell

FAT4 MYO1A MYO5B DYNC2H1 CDH23 DUOX2 FABP2 SPTBN5 SLC9A3 KCNA1 CLCN5 SLCO1A2 PKHD1

1.23e-0459213513GO:0045177
GeneOntologyCellularComponentcell cortex region

MYO5B FABP2 SPTBN5 UNC13C

2.02e-04451354GO:0099738
GeneOntologyCellularComponent9+0 non-motile cilium

CACNA1F MYO5A TULP1 SPTBN5 GUCY2D PKHD1

4.82e-041531356GO:0097731
GeneOntologyCellularComponentrecycling endosome

MYO5A MYO5B VPS50 SLC9A3 FIG4 ATP11A RAB11FIP3

6.08e-042221357GO:0055037
GeneOntologyCellularComponentpostsynaptic recycling endosome membrane

MYO5B RAB11FIP3

6.11e-0461352GO:0098944
GeneOntologyCellularComponentphotoreceptor outer segment

CACNA1F MYO5A TULP1 SPTBN5 GUCY2D

7.73e-041111355GO:0001750
GeneOntologyCellularComponentlipid droplet

RAB40A FIG4 RAB40AL VPS13A RAB40B

9.43e-041161355GO:0005811
GeneOntologyCellularComponentBarr body

MACROH2A1 MACROH2A2

1.13e-0381352GO:0001740
DomainP-loop_NTPase

DDX47 MYH3 MYO1A MYO5A MYO5B DYNC2H1 RAB40A AAGAB ABCA10 ABCA9 GFM2 RHEB HELB DDX46 SBNO1 SLFN13 HS2ST1 RHOBTB2 MCM9 RAB40AL UCK2 RAB40B

1.80e-0784813522IPR027417
DomainChannel_four-helix_dom

CACNA1F CACNA1S SLC9C2 KCNA1 KCNA10 SCN2A

3.42e-06571356IPR027359
Domain-

CACNA1F CACNA1S SLC9C2 KCNA1 KCNA10 SCN2A

3.42e-065713561.20.120.350
Domain-

DDX47 DYNC2H1 RAB40A AAGAB ABCA10 ABCA9 GFM2 RHEB HELB DDX46 SBNO1 SLFN13 HS2ST1 RHOBTB2 MCM9 RAB40AL UCK2 RAB40B

7.22e-06746135183.40.50.300
DomainCUB

CSMD3 ADGRG6 BMP1 TLL2 CSMD1

2.71e-05491355PF00431
DomainCUB

CSMD3 ADGRG6 BMP1 TLL2 CSMD1

2.99e-05501355SM00042
Domain-

CSMD3 ADGRG6 BMP1 TLL2 CSMD1

3.62e-055213552.60.120.290
DomainCUB

CSMD3 ADGRG6 BMP1 TLL2 CSMD1

3.98e-05531355PS01180
DomainCore_histone_macro-H2A

MACROH2A1 MACROH2A2

5.19e-0521352IPR021171
DomainCUB_dom

CSMD3 ADGRG6 BMP1 TLL2 CSMD1

5.67e-05571355IPR000859
DomainCation/H_exchanger_CPA1

SLC9C2 SLC9C1 SLC9A3

5.84e-05111353IPR018422
DomainNa_H_Exchanger

SLC9C2 SLC9C1 SLC9A3

1.27e-04141353PF00999
DomainCation/H_exchanger

SLC9C2 SLC9C1 SLC9A3

1.27e-04141353IPR006153
DomainBMP_1/tolloid-like

BMP1 TLL2

1.55e-0431352IPR015446
DomainVPS13

VPS13D VPS13A

1.55e-0431352IPR026847
DomainVPS13_mid_rpt

VPS13D VPS13A

1.55e-0431352PF16910
DomainVPS13

VPS13D VPS13A

1.55e-0431352PF16908
DomainVPS13_N2

VPS13D VPS13A

1.55e-0431352IPR031646
DomainVPS13_mid_rpt

VPS13D VPS13A

1.55e-0431352IPR031642
DomainMyosin_head_motor_dom

MYH3 MYO1A MYO5A MYO5B

1.59e-04381354IPR001609
DomainMYOSIN_MOTOR

MYH3 MYO1A MYO5A MYO5B

1.59e-04381354PS51456
DomainMyosin_head

MYH3 MYO1A MYO5A MYO5B

1.59e-04381354PF00063
DomainMYSc

MYH3 MYO1A MYO5A MYO5B

1.59e-04381354SM00242
DomainIon_trans_dom

CACNA1F CACNA1S SLC9C1 KCNA1 KCNA10 SCN2A

1.80e-041141356IPR005821
DomainIon_trans

CACNA1F CACNA1S SLC9C1 KCNA1 KCNA10 SCN2A

1.80e-041141356PF00520
DomainIQ

MYH3 MYO1A MYO5A MYO5B SCN2A

3.02e-04811355SM00015
DomainCyt_P450_E_grp-I_CYP2A-like

CYP2A7 CYP2A13

3.08e-0441352IPR008067
DomainSHR-BD

VPS13D VPS13A

3.08e-0441352IPR009543
DomainVDCC_L_a1su

CACNA1F CACNA1S

3.08e-0441352IPR005446
DomainVPS13_C

VPS13D VPS13A

3.08e-0441352PF16909
DomainVPS13_C

VPS13D VPS13A

3.08e-0441352IPR031645
DomainSHR-BD

VPS13D VPS13A

3.08e-0441352PF06650
DomainSOCS

RAB40A RAB40AL RAB40B

3.85e-04201353SM00253
DomainIQ_motif_EF-hand-BS

MYH3 MYO1A MYO5A MYO5B SCN2A

4.92e-04901355IPR000048
DomainMyosin_S1_N

MYO5A MYO5B

5.11e-0451352IPR008989
DomainIQ

MYH3 MYO1A MYO5A MYO5B SCN2A

5.72e-04931355PS50096
DomainVWA

ITGAL ITIH3 COCH VWA5A

7.17e-04561354PF00092
DomainDilute_dom

MYO5A MYO5B

7.63e-0461352IPR002710
DomainDIL

MYO5A MYO5B

7.63e-0461352PF01843
DomainPeptidase_M12A

BMP1 TLL2

7.63e-0461352IPR001506
DomainAstacin

BMP1 TLL2

7.63e-0461352PF01400
DomainDILUTE

MYO5A MYO5B

7.63e-0461352PS51126
DomainDIL

MYO5A MYO5B

7.63e-0461352SM01132
DomainCa_chan_IQ

CACNA1F CACNA1S

1.06e-0371352SM01062
DomainCa_chan_IQ

CACNA1F CACNA1S

1.06e-0371352PF08763
DomainVDCC_a1su_IQ

CACNA1F CACNA1S

1.06e-0371352IPR014873
DomainGPHH

CACNA1F CACNA1S

1.06e-0371352PF16905
DomainGPHH_dom

CACNA1F CACNA1S

1.06e-0371352IPR031649
DomainSmall_GTP-bd_dom

RAB40A GFM2 RHEB RHOBTB2 RAB40AL RAB40B

1.36e-031671356IPR005225
DomainChorein_N

VPS13D VPS13A

1.41e-0381352PF12624
DomainVIT

ITIH3 VWA5A

1.41e-0381352PF08487
DomainK_chnl_volt-dep_Kv1

KCNA1 KCNA10

1.41e-0381352IPR003972
DomainVPS13_N

VPS13D VPS13A

1.41e-0381352IPR026854
DomainVIT

ITIH3 VWA5A

1.41e-0381352SM00609
DomainIQ

MYH3 MYO1A MYO5A MYO5B

1.74e-03711354PF00612
DomainA1pp

MACROH2A1 MACROH2A2

1.81e-0391352SM00506
DomainMacro

MACROH2A1 MACROH2A2

1.81e-0391352PF01661
DomainVIT

ITIH3 VWA5A

2.25e-03101352PS51468
DomainMacro_dom

MACROH2A1 MACROH2A2

2.25e-03101352IPR002589
DomainVIT

ITIH3 VWA5A

2.25e-03101352IPR013694
DomainMACRO

MACROH2A1 MACROH2A2

2.25e-03101352PS51154
DomainVDCCAlpha1

CACNA1F CACNA1S

2.25e-03101352IPR002077
DomainSOCS_box

RAB40A RAB40AL RAB40B

2.59e-03381353PF07525
DomainSOCS_box

RAB40A RAB40AL RAB40B

2.79e-03391353SM00969
DomainSOCS_box

RAB40A RAB40AL RAB40B

2.79e-03391353IPR001496
DomainSOCS

RAB40A RAB40AL RAB40B

2.79e-03391353PS50225
DomainVWFA

ITGAL ITIH3 COCH VWA5A

2.95e-03821354PS50234
DomainRas

RAB40A RHEB RHOBTB2 RAB40AL RAB40B

3.10e-031361355PF00071
DomainVWA

ITGAL ITIH3 COCH VWA5A

3.22e-03841354SM00327
DomainABC_A

ABCA10 ABCA9

3.26e-03121352IPR026082
DomainEGF_CA

FAT4 FAT3 BMP1 TLL2

3.51e-03861354PF07645
DomainCyt_P450_E_grp-I

CYP2A7 CYP2A13 CYP2R1

4.20e-03451353IPR002401
Domain-

EXD1 POLE PIWIL3

4.75e-034713533.30.420.10
Domain-

FAT4 CALR3 FAT3 ADGRG6

5.00e-039513542.60.120.200
DomainEGF_Ca-bd_CS

FAT4 FAT3 BMP1 TLL2

5.39e-03971354IPR018097
DomainEGF_CA

FAT4 FAT3 BMP1 TLL2

5.79e-03991354PS01187
DomainVWF_A

ITGAL ITIH3 COCH VWA5A

5.79e-03991354IPR002035
DomainSmall_GTPase

RAB40A RHEB RHOBTB2 RAB40AL RAB40B

6.15e-031601355IPR001806
DomainHistone_H2A_C

MACROH2A1 MACROH2A2

6.57e-03171352IPR032454
DomainHistone_H2A_C

MACROH2A1 MACROH2A2

6.57e-03171352PF16211
DomainCyt_P450_CS

CYP2A7 CYP2A13 CYP2R1

6.65e-03531353IPR017972
Pubmed

Rab40b and Tks5 interact at invadopodia during metastasis.

RAB40A RAB40AL RAB40B

5.82e-075136327909076
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

DNAJB11 NUP107 DYNC2H1 POLE UGGT1 MARCHF7 EXOC5 VPS13D COCH VPS13A UCK2 KPNA3

5.02e-066061361236538041
Pubmed

Macro histone variants are critical for the differentiation of human pluripotent cells.

MACROH2A1 MACROH2A2

1.52e-052136223595991
Pubmed

MACROH2A2, a new member of the MARCOH2A core histone family.

MACROH2A1 MACROH2A2

1.52e-052136211262398
Pubmed

HIV-1 Nef employs two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling.

LCK PAK2

1.52e-052136218030346
Pubmed

Scn2a deletion improves survival and brain-heart dynamics in the Kcna1-null mouse model of sudden unexpected death in epilepsy (SUDEP).

KCNA1 SCN2A

1.52e-052136228334922
Pubmed

MacroH2A restricts inflammatory gene expression in melanoma cancer-associated fibroblasts by coordinating chromatin looping.

MACROH2A1 MACROH2A2

1.52e-052136237605008
Pubmed

Expression of CYP2A genes in human liver and extrahepatic tissues.

CYP2A7 CYP2A13

1.52e-052136210353262
Pubmed

A myosin family tree.

MYO5A CDH23

1.52e-052136210984423
Pubmed

Chloride channel (Clc)-5 is necessary for exocytic trafficking of Na+/H+ exchanger 3 (NHE3).

SLC9A3 CLCN5

1.52e-052136221561868
Pubmed

Kv1.1 deficiency alters repetitive and social behaviors in mice and rescues autistic-like behaviors due to Scn2a haploinsufficiency.

KCNA1 SCN2A

1.52e-052136233484493
Pubmed

MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency.

MACROH2A1 MACROH2A2

1.52e-052136223463008
Pubmed

Histone macroH2A isoforms predict the risk of lung cancer recurrence.

MACROH2A1 MACROH2A2

1.52e-052136219648962
Pubmed

The N-terminus of Nef from HIV-1/SIV associates with a protein complex containing Lck and a serine kinase.

LCK PAK2

1.52e-05213629075929
Pubmed

X chromosome inactivation and differentiation occur readily in ES cells doubly-deficient for macroH2A1 and macroH2A2.

MACROH2A1 MACROH2A2

1.52e-052136221738686
Pubmed

Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.

MYO1A MYO5A MYO5B

2.06e-051413638022818
Pubmed

Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy.

MACROH2A1 CPT2 DPM1 RHEB CNOT6L UCK2 MACROH2A2 RPL15

2.09e-05292136835545034
Pubmed

Simultaneous mutation detection in 90 retinal disease genes in multiple patients using a custom-designed 300-kb retinal resequencing chip.

CACNA1F MYOC CDH23 TULP1 GUCY2D

2.43e-0587136520801516
Pubmed

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.

AKAP13 ATP11A CSMD1

2.57e-0515136323583980
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DDX47 DNAJB11 NUP107 DIS3L FAT3 VPS50 MACROH2A1 DPM1 ACTR6 ZNF589 FIBP UCK2 MACROH2A2 CSMD1 KPNA3

3.32e-0511161361531753913
Pubmed

Regulation of bile acid metabolism in mouse models with hydrophobic bile acid composition.

CYP2A7 CYP2A13

4.54e-053136231645370
Pubmed

Identification of two new members of the CSMD gene family.

CSMD3 CSMD1

4.54e-053136212906867
Pubmed

Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.

VPS13D CSMD1

4.54e-053136220610895
Pubmed

Reciprocal regulation of sex-dependent expression of testosterone 15 alpha-hydroxylase (P-450(15 alpha)) in liver and kidney of male mice by androgen. Evidence for a single gene.

CYP2A7 CYP2A13

4.54e-05313623346244
Pubmed

LSH mediates gene repression through macroH2A deposition.

MACROH2A1 MACROH2A2

4.54e-053136233159050
Pubmed

Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue.

CYP2A7 CYP2A13

4.54e-05313622733794
Pubmed

Human Rab small GTPase- and class V myosin-mediated membrane tethering in a chemically defined reconstitution system.

MYO5A MYO5B

4.54e-053136228939769
Pubmed

LSH catalyzes ATP-driven exchange of histone variants macroH2A1 and macroH2A2.

MACROH2A1 MACROH2A2

4.54e-053136234223906
Pubmed

A trans-acting locus regulates transcriptional repression of the female-specific steroid 15 alpha-hydroxylase gene in male mice.

CYP2A7 CYP2A13

4.54e-05313628297477
Pubmed

Lack of the steroid 15 alpha-hydroxylase gene (Cyp2a-4) in wild mouse strain Mus spretus: rapid evolution of the P450 gene superfamily.

CYP2A7 CYP2A13

4.54e-05313628188299
Pubmed

Dysferlin-deficient myotubes show tethering of different membrane compartments characterized by TMEM16E and DHPRα.

CACNA1S ANO5

4.54e-053136232736698
Pubmed

Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases.

BMP1 TLL2

4.54e-053136218824173
Pubmed

The temporal and spatial expression pattern of myosin Va, Vb and VI in the mouse ovary.

MYO5A MYO5B

4.54e-053136216713372
Pubmed

Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction.

CYP2A7 CYP2A13

4.54e-05313628484736
Pubmed

Comparison of hamster and mouse reveals interspecies differences in the regulation of hepatic CYP2A isozymes.

CYP2A7 CYP2A13

4.54e-05313628250953
Pubmed

The structure and characterization of type I P-450(15) alpha gene as major steroid 15 alpha-hydroxylase and its comparison with type II P-450(15) alpha gene.

CYP2A7 CYP2A13

4.54e-05313622703500
Pubmed

Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes.

MYO5A MYO5B

4.54e-053136224508725
Pubmed

Cerium-induced strain-dependent increase in Cyp2a-4/5 (cytochrome P4502a-4/5) expression in the liver and kidneys of inbred mice.

CYP2A7 CYP2A13

4.54e-05313621417950
Pubmed

Impact of nicotine metabolism on nicotine's pharmacological effects and behavioral responses: insights from a Cyp2a(4/5)bgs-null mouse.

CYP2A7 CYP2A13

4.54e-053136224045421
Pubmed

Highly homologous mouse Cyp2a4 and Cyp2a5 genes are differentially expressed in the liver and both express long non-coding antisense RNAs.

CYP2A7 CYP2A13

4.54e-053136232987105
Pubmed

Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.

MYO5A MYO5B

4.54e-053136224339992
Pubmed

ZFR coordinates crosstalk between RNA decay and transcription in innate immunity.

MACROH2A1 MACROH2A2

4.54e-053136229559679
Pubmed

Alteration of the substrate specificity of mouse 2A P450s by the identity of residue-209: steroid-binding site and orientation.

CYP2A7 CYP2A13

4.54e-053136222217847
Pubmed

Mouse steroid 15 alpha-hydroxylase gene family: identification of type II P-450(15)alpha as coumarin 7-hydroxylase.

CYP2A7 CYP2A13

4.54e-05313622765478
Pubmed

Genetic analysis of the role of proteolysis in the activation of latent myostatin.

BMP1 TLL2

4.54e-053136218286185
Pubmed

Sexual dimorphism of testosterone 15 alpha-hydroxylase mRNA levels in mouse liver. cDNA cloning and regulation.

CYP2A7 CYP2A13

4.54e-05313622415518
Pubmed

Differential distribution of CYP2A6 and CYP2A13 in the human respiratory tract.

CYP2A7 CYP2A13

4.54e-053136222890016
Pubmed

Structural insights into functional overlapping and differentiation among myosin V motors.

MYO5A MYO5B

4.54e-053136224097982
Pubmed

macroH2A1 histone variant represses rDNA transcription.

MACROH2A1 MACROH2A2

4.54e-053136224071584
Pubmed

Mice without macroH2A histone variants.

MACROH2A1 MACROH2A2 ATP11A

5.41e-0519136325312643
Pubmed

Six1 and Six4 gene expression is necessary to activate the fast-type muscle gene program in the mouse primary myotome.

MYH3 MYL1 VGLL2

6.35e-0520136319962975
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

KBTBD3 BDP1 MYO5A MACROH2A1 ADGRG6 ERGIC1 PTPRS HS2ST1 ZNF589 VPS41 AKAP13 MACROH2A2 ATP11A RAB40B CSMD1 REEP5 TSEN15

7.44e-0514891361728611215
Pubmed

Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport.

MYO5A RAB40A RAB40AL RAB40B

8.06e-0558136411856727
Pubmed

Transcriptional regulation by HNF-4 of the steroid 15alpha-hydroxylase P450 (Cyp2a-4) gene in mouse liver.

CYP2A7 CYP2A13

9.06e-05413629408084
Pubmed

Circadian expression of the steroid 15 alpha-hydroxylase (Cyp2a4) and coumarin 7-hydroxylase (Cyp2a5) genes in mouse liver is regulated by the PAR leucine zipper transcription factor DBP.

CYP2A7 CYP2A13

9.06e-054136210490589
Pubmed

Analysis of the human VPS13 gene family.

VPS13D VPS13A

9.06e-054136215498460
Pubmed

Structural basis of myosin V Rab GTPase-dependent cargo recognition.

MYO5A MYO5B

9.06e-054136224248336
Pubmed

Two steroid 15 alpha-hydroxylase genes and a homologous gene family in mice.

CYP2A7 CYP2A13

9.06e-05413621970547
Pubmed

Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.

CACNA1F CACNA1S

9.06e-054136220937870
Pubmed

Alternative splicing in class V myosins determines association with Rab10.

MYO5A MYO5B

9.06e-054136219008234
Pubmed

Genetic testing for retinal dystrophies and dysfunctions: benefits, dilemmas and solutions.

CACNA1F GUCY2D

9.06e-054136217651254
Pubmed

The histone variant macroH2A is an epigenetic regulator of key developmental genes.

MACROH2A1 MACROH2A2

9.06e-054136219734898
Pubmed

A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP.

CYP2A7 CYP2A13

9.06e-05413627565685
Pubmed

Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA.

MACROH2A1 MACROH2A2

9.06e-054136215621527
Pubmed

Rab40C is a novel Varp-binding protein that promotes proteasomal degradation of Varp in melanocytes.

RAB40A RAB40B

9.06e-054136225661869
Pubmed

Resveratrol improves health and survival of mice on a high-calorie diet.

CYP2A7 CYP2A13 SLCO1A2

1.42e-0426136317086191
Pubmed

The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment.

MACROH2A1 MACROH2A2

1.51e-045136228934364
Pubmed

Histone H2A variants and the inactive X chromosome: identification of a second macroH2A variant.

MACROH2A1 MACROH2A2

1.51e-045136211331621
Pubmed

Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis.

BMP1 TLL2

1.51e-045136210479448
Pubmed

Analysis of histone variant constraint and tissue expression suggests five potential novel human disease genes: H2AFY2, H2AFZ, H2AFY, H2AFV, H1F0.

MACROH2A1 MACROH2A2

1.51e-045136235072799
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

NUP107 VPS50 MACROH2A1 DPM1 EXOC5 PARVA GEMIN4 MACROH2A2 CARS2

1.58e-04498136936634849
Pubmed

Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice.

MYO5A MYO5B CLCN5

2.20e-0430136328077597
Pubmed

Functional redundancy of the muscle-specific transcription factors Myf5 and myogenin.

MYH3 MYL1

2.25e-04613628587605
Pubmed

A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles.

CYP2A7 CYP2A13

2.25e-04613627668294
Pubmed

Type 3 and type 1 ryanodine receptors are localized in triads of the same mammalian skeletal muscle fibers.

CACNA1S MYH3

2.25e-046136210444070
Pubmed

Role of Nef in HIV-1 replication and pathogenesis.

LCK PAK2

2.25e-046136217586321
Pubmed

Organization and evolution of the cytochrome P450 CYP2A-2B-2F subfamily gene cluster on human chromosome 19.

CYP2A7 CYP2A13

2.25e-04613628587134
Pubmed

Physical mapping of potassium channel gene clusters on mouse chromosomes three and six.

KCNA1 KCNA10

2.25e-04613629286706
Pubmed

Hes1 marks peri-condensation mesenchymal cells that generate both chondrocytes and perichondrial cells in early bone development.

MYH3 MYL1

2.25e-046136237172728
Pubmed

Trip6 promotes dendritic morphogenesis through dephosphorylated GRIP1-dependent myosin VI and F-actin organization.

MYO5A MYO5B

2.25e-046136225673849
Pubmed

Pore size matters for potassium channel conductance.

KCNA1 KCNA10

3.15e-047136227619418
Pubmed

Organization and evolution of the Cyp2 gene cluster on mouse chromosome 7, and comparison with the syntenic human cluster.

CYP2A7 CYP2A13

3.15e-047136214630516
Pubmed

Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.

FAT4 FAT3

3.15e-047136222510986
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1F CACNA1S

3.15e-047136212900400
Pubmed

Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes.

MYO5A CDH23

3.15e-047136215572405
Pubmed

Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.

FAT4 FAT3

3.15e-047136216059920
Pubmed

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses.

CYP2A7 CYP2A13

3.15e-04713629630227
Pubmed

A stromal cell niche sustains ILC2-mediated type-2 conditioning in adipose tissue.

ITGAL IL7R

3.15e-047136231248899
Pubmed

Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection.

PKD1L1 TULP1

3.15e-047136222841784
Pubmed

NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.

MC4R PKHD1

4.19e-048136219557197
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1F CACNA1S

4.19e-048136228330839
Pubmed

Evolution of the Rab family of small GTP-binding proteins.

RAB40A RAB40B

4.19e-048136211697911
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1F CACNA1S

5.37e-049136216382099
Pubmed

Genetics of dizziness: cerebellar and vestibular disorders.

KCNA1 COCH

5.37e-049136224275721
Pubmed

Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder.

CYP2A7 CYP2A13

5.37e-049136237838304
Pubmed

Muscle-specific gene expression during myogenesis in the mouse.

MYH3 MYL1

5.37e-04913627787235
Pubmed

Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function.

LCK PAK2

5.37e-049136222537596
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYH3 CYP2A13 MYO1A MYO5A MYO5B PCDHGA4 OR9Q2 UGGT1 DUOX2 MACROH2A1 CLCN5 SBNO1 VPS13A PKHD1 ATP11A

5.39e-0414421361535575683
Pubmed

The SOCS box: a tale of destruction and degradation.

RAB40A RAB40AL RAB40B

5.59e-0441136312076535
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

DNAJB11 MACROH2A1 LMTK3 ITIH3 CCM2 DDX46 MACROH2A2 KPNA3

5.86e-04475136831040226
GeneFamilyMyosins, class V

MYO5A MYO5B

9.24e-05310121100
GeneFamilyCadherin related

FAT4 FAT3 CDH23

1.09e-0417101324
GeneFamilyBone morphogenetic proteins|Astacins

BMP1 TLL2

4.57e-0461012894
GeneFamilyMyosins, class I

MYO1A MYO1H

8.46e-04810121097
GeneFamilyCytochrome P450 family 2

CYP2A7 CYP2A13 CYP2R1

9.73e-043510131001
GeneFamilyATP binding cassette subfamily A

ABCA10 ABCA9

2.69e-03141012805
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F FAT4 FAT3 ANO5 CSMD3 SCN2A PKHD1 ADAMTS20 UNC13C CSMD1

2.79e-10184136102cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F FAT4 FAT3 ANO5 CSMD3 SCN2A PKHD1 ADAMTS20 UNC13C CSMD1

2.79e-1018413610ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F FAT4 FAT3 ANO5 CSMD3 SCN2A PKHD1 ADAMTS20 UNC13C CSMD1

2.79e-10184136102b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MACROH2A1 CSMD3 FGL2 SCN2A DIAPH2 PKHD1 ADAMTS20 CSMD1 PIWIL3

6.19e-09186136923b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2H1 ABCA10 ABCA9 S100A2 SCN2A PKHD1 UNC13C

1.78e-061871367f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellfacs-Trachea-nan-3m-Mesenchymal-smooth_muscle_cell_of_trachea|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL1 VGLL2 AGBL4 KCNA1 ADAMTS20 UCK2 CSMD1

1.84e-061881367794fc1d9a726945c42f7eac221eed938309b47a9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2H1 ABCA10 ABCA9 S100A2 SCN2A PKHD1 UNC13C

1.91e-061891367e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellCOVID-19-Heart-T_cell|Heart / Disease (COVID-19 only), tissue and cell type

LCK SAMSN1 ITGAL CSMD3 RHAG CSMD1 IL7R

1.98e-061901367e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2H1 ABCA10 ABCA9 CNOT6L CLCN5 SCN2A UNC13C

2.35e-061951367a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellDendritic_Cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

F13A1 FGL2 SPTBN5 KCNA1 COCH

6.33e-06851365d2776a2c8d1721dbbd7d5dc868a3810e30dd9064
ToppCellLPS-antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1F MYO5B ZSWIM9 SCN2A ZNF589 RMC1

6.83e-0615013669cb3332924bd67c966873343c14445e30d3f384f
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUP107 CDH23 LCK ITGAL FGL2 MCM9

7.94e-06154136675eac6970259a6916fcfa6d3400509cfa2d98d9d
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POLE FAT3 DUOX2 CSMD3 PKHD1 AIFM3

1.06e-051621366bf886e22ff2a20353499004b53f25fb9e6574896
ToppCelldroplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 LCK HECW2 GUCY2D MCM9 IL7R

1.26e-051671366a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

DYNC2H1 SAMSN1 S100A2 CNOT6L PTGR1 ZNF589

1.54e-051731366b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DYNC2H1 SAMSN1 S100A2 CNOT6L PTGR1 ZNF589

1.70e-051761366437cfc5e06416bb0fc76d1f9dc106f74e279e880
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

POLE CLCN5 PKHD1 UNC13C ATP11A RAB11FIP3

2.25e-051851366636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LCK SAMSN1 ITGAL HELB CNOT6L IL7R

2.32e-051861366bd3bd022b575d9b0ef90d50a5cb874085a827b77
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LCK SAMSN1 ITGAL HELB CNOT6L IL7R

2.32e-051861366924cc357b4c4ce8e9b05773bdab544f0b65474cc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5B ADGRG6 AGBL4 PKHD1 ATP11A RAB11FIP3

2.54e-05189136628b502611829e4a24caff2562545c7db97686099
ToppCellControl-T_cells-CD4+_T_cells|Control / group, cell type (main and fine annotations)

LCK SAMSN1 ITGAL HELB CNOT6L IL7R

2.61e-0519013660733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SAMSN1 SLC9C1 PTGR1 SCN2A PKHD1 UNC13C

2.69e-0519113663e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellCOVID-19-lung-CD4+_Treg|COVID-19 / Disease (COVID-19 only), tissue and cell type

LCK SAMSN1 ITGAL HELB CNOT6L IL7R

2.69e-0519113665a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCellCOVID-19-lung-CD4+_Treg|lung / Disease (COVID-19 only), tissue and cell type

LCK SAMSN1 ITGAL HELB CNOT6L IL7R

2.69e-05191136673ea3078c1f55cd47e4d99e77b3ce4ff17549d49
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SAMSN1 FGL2 S100A2 AGBL4 PTGR1 SCN2A

2.77e-0519213660bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

DYNC2H1 ABCA10 ABCA9 KCNT2 PTPRS DIAPH2

2.77e-051921366356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYL1 MYO5B RHOBTB2 PKHD1 AKAP13 ATP11A

2.77e-05192136629f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SAMSN1 SLC9C1 PTGR1 SCN2A PKHD1 UNC13C

2.94e-05194136669bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

DYNC2H1 ABCA10 ABCA9 KCNT2 PTPRS DIAPH2

3.02e-051951366ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT3 CSMD3 AGBL4 SCN2A VPS13A CSMD1

3.02e-0519513662e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-T_reg|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LCK SAMSN1 HELB CCM2 CNOT6L IL7R

3.29e-0519813667608f67959e1cda7b10e57fd3af2f96216ebe7e9
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

FAT4 FAT3 ADGRG6 KCNT2 UNC13C RPL15

3.39e-0519913665b9d355795dd03a22f0961dfd143425c367a4654
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

FAT4 FAT3 ABCA10 ABCA9 KCNT2 PTPRS

3.39e-0519913664bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LCK SAMSN1 ITGAL HELB CNOT6L IL7R

3.48e-052001366cded40d5069a6fdbd90ac9a2a0bbef11727b28d5
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

BDP1 CSMD3 AGBL4 HECW2 SCN2A CSMD1

3.48e-05200136648d801219bc771d6c7e151dc88ca4c179988de85
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LCK SAMSN1 ITGAL HELB CNOT6L IL7R

3.48e-052001366c6c2b39359c65c9444987d02d1c899dff2ad1366
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LCK SAMSN1 ITGAL HELB CNOT6L IL7R

3.48e-0520013669de4d6ebb7e9bee5d811519eb05913ef30f70786
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LCK SAMSN1 ITGAL HELB CNOT6L IL7R

3.48e-052001366f7a9d8b99de19e9842422bada348d940e0863645
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-OPC_related|GW26 / Sample Type, Dataset, Time_group, and Cell type.

TULP1 S100A2 PTGR1 SLCO1A2 TGDS

6.36e-051371365264d5e06c37d1a9ef7748091b67d2a5aa803096e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-OPC_related-Oligodendrocyte/OPC|GW26 / Sample Type, Dataset, Time_group, and Cell type.

TULP1 S100A2 PTGR1 SLCO1A2 TGDS

6.36e-0513713658ce463d1d74ac0ce80b812217d6bd76a788f14d2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2H1 ABCA10 SCN2A AIFM3 UNC13C

7.05e-0514013655e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCellTCGA-Uterus|World / Sample_Type by Project: Shred V9

CACNA1S MYH3 MYL1 VGLL2 TULP1

8.05e-0514413657efb45286ebf2dbfb9125fd6373f28dccb029a2e
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FAT4 EXD1 CSMD3 AGBL4 CSMD1

9.46e-051491365c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FAT4 EXD1 CSMD3 AGBL4 CSMD1

9.46e-051491365a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PCDHGA4 PKD1L1 TULP1 REEP5

1.06e-048013640d02b242164d27f38f70ed77b106612fc7a3abca
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PCDHGA4 PKD1L1 TULP1 REEP5

1.06e-04801364313344cf7309bc17ca131b92a91b24489df577e2
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocyte.Tnr.Tmem2_(Tmem2)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PCDHGA4 PKD1L1 TULP1 REEP5

1.06e-04801364b95e4456adb7f7d42825351f010376c10bb35380
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A DYNC2H1 ITGAL F13A1 ADGRG6

1.07e-0415313650ef7c45cdd854c79e527006034029767f8e108b2
ToppCellT_cells-Treg_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

LAYN LCK SAMSN1 CNOT6L IL7R

1.07e-041531365ac793f3176ac3c42c23e7dffc12dd1b057bae4ae
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POLE CDH23 LCK UCK2 IL7R

1.07e-0415313650ad401cb70b9edfc6ae6ccba6879c6c2b6c4d296
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL1 MYO1A FAT3 ANO5 HECW2

1.14e-0415513658fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDH23 LCK COCH CNOT6L IL7R

1.21e-041571365cbb08d5c151f0622123276926a2a15bb7d271e90
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDH23 LCK COCH CNOT6L IL7R

1.21e-04157136516581e2399a211633f870dce326c75ff4b6a5fe6
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1F ABCA9 F13A1 CLCN5 CYP2R1

1.28e-041591365c0e55f25271f788c08fa4b95186501fc27b2ec39
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-TRGV4_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAYN SAMSN1 CNOT6L AKAP13 IL7R

1.44e-04163136511cc18f36604d9a5f4e7fb8626a8f0fb141da5e1
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POLE LCK ITGAL S100A2 IL7R

1.53e-0416513655f606959a060b1ae241217889560c6761ac73bbb
ToppCellfacs-Lung-Endomucin-24m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPAG4 MYL1 PNLIP EID3 FABP2

1.57e-04166136564a0762eb9cafb6a079df296ed677c8e0ae0efa7
ToppCellmild_COVID-19-Treg|World / disease group, cell group and cell class (v2)

LAYN LCK SAMSN1 CCM2 IL7R

1.61e-04167136569330689b6e353c8ee9ea1b63a5eac6ab38d456f
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S DNAJB11 CDH23 ITGAL FGL2

1.66e-04168136541da200bbff5c663c39f67c38d6d5f43b0ad9494
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|356C / Donor, Lineage, Cell class and subclass (all cells)

LCK SAMSN1 CNOT6L AKAP13 IL7R

1.66e-0416813659d6ca10c272aea28082c09d469940f7232f6461c
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S DNAJB11 CDH23 ITGAL FGL2

1.66e-041681365a77259c13508f19186d7b0f80b34dc6d89497ab5
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S MYO1H CDH23 ITGAL FGL2

1.66e-041681365bc7d5f0e5d222922eaf1c8e8c87aab189209d6b6
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV5/7_gdT|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAYN LCK HELB SPTBN5 AIFM3

1.66e-041681365235c368669c017e13a7312fce3d8b91d7d106c7a
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADGRG6 AGBL4 KCNT2 SLCO1A2 PKHD1

1.66e-041681365a086c306be430adf0632ba53e98cd8014d2de330
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1A ITIH3 FGL2 ADGRG6 HECW2

1.75e-0417013658e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1A ITIH3 FGL2 ADGRG6 HECW2

1.75e-04170136567d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F ABCA9 F13A1 VWA5A DIAPH2

1.75e-041701365a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F ABCA9 F13A1 VWA5A DIAPH2

1.75e-041701365ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellCOVID-19-Heart-T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

EXD1 CSMD3 RHAG UNC13C CSMD1

1.80e-041711365b2e753e811a7639956994609f73efcdb62d04f82
ToppCell10x3'2.3-week_17-19-Myeloid_DC-DC-tDC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CACNA1F MYO1A SLC9C2 FGL2 RAB40AL

1.80e-041711365b327fb7813a3cdae06c8a4f8a0c256e9a20132f6
ToppCelldroplet-Pancreas-PANCREAS-30m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S LCK ITGAL F13A1 IL7R

1.85e-041721365480f409405d1d35804629e81fc6ec5873a085983
ToppCelldroplet-Pancreas-PANCREAS-30m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S LCK ITGAL F13A1 IL7R

1.85e-04172136517938d191e28f88cccf180dc1aaf453a255fc031
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPAG4 LAYN SAMSN1 FGL2 RAB11FIP3

1.85e-0417213658a6a2b4c6654bc976e60a02d0e7303a9071ed55f
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 ADGRG6 GOT1L1 KCNT2 UNC13C

1.90e-0417313651f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA10 ABCA9 CNOT6L SCN2A PKHD1

1.90e-0417313650c74bdb40e635d906fd180412c23bf7fed61621e
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S MYO5A CDH23 FGL2 UCK2

1.90e-04173136560e427f6c7d953cef5f692043670ff0b49cdce72
ToppCellfacs-Marrow-T_cells-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S DNAJB11 CDH23 FGL2 ERGIC1

1.95e-0417413653b1ee39e85e5f0d6b17fb3051dbfae66cb2be6ee
ToppCellInt-URO-Lymphocyte-T_NK-NK_CD56bright|Int-URO / Disease, Lineage and Cell Type

MYH3 FAT3 LCK SLFN13 IL7R

1.95e-04174136593c7acd5941a5f235ec4c57461f78ee2871e7336
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S MYO5A CDH23 FGL2 UCK2

1.95e-041741365c92eec5a14ca5269673582dd115ead8516e64c3e
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S CDH23 LCK ITGAL IL7R

2.01e-041751365b56968904dccaee8553aa14ce874cfec6bd9d7b9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDH23 ABCA10 ABCA9 KCNT2 PTPRS

2.01e-041751365795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S CDH23 LCK ITGAL IL7R

2.01e-041751365c63802e464b6e4f1d2a9c11e65ee89d607216154
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_Tfh|metastatic_Brain / Location, Cell class and cell subclass

LCK SAMSN1 CNOT6L ZNF589 AKAP13

2.01e-041751365b732c6a423c28856211002107d8c611dcfb6f265
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5A SAMSN1 ITGAL ABCA9 F13A1

2.01e-041751365a8b05972e1bec4de73feaa6c4a9bcbe6b50c8044
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A FAT3 ABCA9 GFM2 AKAP13

2.01e-0417513651ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LCK ITGAL SLFN13 UNC13C IL7R

2.01e-041751365f2c3e0f728a43d6988e793c8a50c964f7447db82
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PNLIP CSMD3 KCNT2 PKHD1 CSMD1

2.01e-041751365887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S PCDHGA4 MYO1H CDH23 ITGAL

2.11e-04177136541cbb2c109eaa7be366fc0510cce64abc06837b4
ToppCellfacs-Skin-Anagen-3m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCK SAMSN1 ITGAL KCNT2 IL7R

2.11e-0417713657853430fb0d1a18d835e8956777e0616c5d7d412
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCK SAMSN1 LMTK3 ITGAL IL7R

2.11e-04177136531201a72b7c1bdb0eff892b7072a35c80fd34727
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCK SAMSN1 LMTK3 ITGAL IL7R

2.11e-04177136589d0131320cd96af8b0ee54f0f4d4771d17ef44e
ToppCellfacs-Skin-Anagen-3m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCK SAMSN1 ITGAL KCNT2 IL7R

2.11e-041771365395f005f019aabb18738d3a10a04c37f216deda3
ToppCellfacs-Skin-Anagen-3m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCK SAMSN1 ITGAL KCNT2 IL7R

2.11e-0417713659a5bf67a801826d094f679dd2189b62296c9694f
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LCK ITGAL HELB ZSWIM9 IL7R

2.17e-0417813655101a45595cd8d702f911afadf1eb0ee10bdcefc
ToppCelldroplet-Tongue-nan-24m-Myeloid-basal_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCK SAMSN1 ITGAL FGL2 IL7R

2.17e-0417813659423e209de94d26e96117581c95dc069850225d3
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCK ITGAL FGL2 COCH IL7R

2.17e-04178136593bd3205081b97e00e7a1bbaf4a311075b9cbfe8
ToppCelldroplet-Kidney-nan-18m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCK SAMSN1 ITGAL FGL2 IL7R

2.23e-04179136558be9ab455875035978c78ba7d7e4b3c9f3dc4e5
ToppCelldroplet-Tongue-nan-24m-Myeloid-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCK SAMSN1 ITGAL FGL2 IL7R

2.23e-0417913651b079d80f789473701c781f3431ad306e9766797
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LCK CYP2R1 ANKRD13C VPS13A IL7R

2.23e-0417913656bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 ADGRG6 GOT1L1 KCNT2 UNC13C

2.29e-04180136501f2e5d96016823482f89ba503d007d4bd88eeac
Diseaseautosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)

VPS13D VPS13A

6.12e-0531342DOID:0111611 (implicated_via_orthology)
DiseaseTimothy syndrome (implicated_via_orthology)

CACNA1F CACNA1S

1.22e-0441342DOID:0060173 (implicated_via_orthology)
Diseasecongenital stationary night blindness (is_implicated_in)

CACNA1F GUCY2D

1.22e-0441342DOID:0050534 (is_implicated_in)
DiseaseCiliopathies

DYNC2H1 CDH23 TULP1 GUCY2D PKHD1

1.50e-041101345C4277690
Diseasesugar consumption measurement

MYOC UGGT1 PTGR1 PKHD1 CSMD1

2.25e-041201345EFO_0010158
DiseaseGoiter

DUOX2 CLCN5

4.24e-0471342C0018021
Diseasehepatitis C virus infection, cirrhosis of liver

PKD1L1 TULP1

4.24e-0471342EFO_0001422, EFO_0003047
Diseaseage-related hearing impairment

CDH23 CSMD3 CCM2 COCH FIG4 PARVA CSMD1

7.21e-043241347EFO_0005782
Diseaseplasma trimethylamine N-oxide measurement

FIG4 RHOBTB2

8.99e-04101342EFO_0005691
Diseaseepilepsy (implicated_via_orthology)

KCNA1 KCNT2 KCNA10 SCN2A UNC13C

9.10e-041631345DOID:1826 (implicated_via_orthology)
DiseaseCystic Kidney Diseases

DNAJB11 FAT4

1.10e-03111342C1691228
DiseaseDiarrhea

MYO5B SLC9A3

1.10e-03111342C0011991
DiseaseCongenital myopathy (disorder)

CACNA1S MYL1

1.31e-03121342C0270960
DiseaseColorectal Carcinoma

POLE CSMD3 ABCA10 ABCA9 RHEB KCNA10 PTPRS SLCO1A2 VPS13A PKHD1

1.41e-0370213410C0009402
Diseasesquamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma

PKHD1 CSMD1

1.55e-03131342EFO_0000707, EFO_0004193, EFO_0007932
DiseaseDrug habituation

CSMD3 AGBL4 PARVA CSMD1

1.90e-031151344C0013170
DiseaseDrug abuse

CSMD3 AGBL4 PARVA CSMD1

1.90e-031151344C0013146
DiseasePrescription Drug Abuse

CSMD3 AGBL4 PARVA CSMD1

1.90e-031151344C4316881
DiseaseSubstance-Related Disorders

CSMD3 AGBL4 PARVA CSMD1

1.90e-031151344C0236969
DiseaseDrug Use Disorders

CSMD3 AGBL4 PARVA CSMD1

1.90e-031151344C0013222
DiseaseDrug Dependence

CSMD3 AGBL4 PARVA CSMD1

1.90e-031151344C1510472
DiseaseSubstance Dependence

CSMD3 AGBL4 PARVA CSMD1

1.90e-031151344C0038580
DiseaseSubstance Use Disorders

CSMD3 AGBL4 PARVA CSMD1

1.90e-031151344C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

CSMD3 AGBL4 PARVA CSMD1

1.90e-031151344C0029231
DiseaseSubstance abuse problem

CSMD3 AGBL4 PARVA CSMD1

1.97e-031161344C0740858
Diseaseantisaccade response measurement

SAMSN1 UNC13C CSMD1

2.13e-03561343EFO_0006874
DiseaseLeber congenital amaurosis

TULP1 GUCY2D

2.36e-03161342cv:C0339527
Diseaseamygdala volume change measurement

PKD1L1 CSMD1

2.36e-03161342EFO_0021490
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

KCNA1 SCN2A

2.36e-03161342C0393706
DiseaseDisorder of eye

CACNA1F MYOC CDH23 TULP1 GUCY2D

2.88e-032121345C0015397
Diseaseobesity (implicated_via_orthology)

FAT4 PNLIP MC4R TULP1 ADAMTS20

3.06e-032151345DOID:9970 (implicated_via_orthology)
Diseasecardiac troponin T measurement

CACNA1S CDH23 ANO5 FIG4 PKHD1

3.31e-032191345EFO_0005043
Diseaseinterstitial lung disease

AKAP13 ATP11A CSMD1

3.55e-03671343EFO_0004244
Diseaseschizophrenia (implicated_via_orthology)

CSMD3 SBNO1 CSMD1

3.70e-03681343DOID:5419 (implicated_via_orthology)
DiseaseArthrogryposis

MYH3 GFM2

4.06e-03211342C0003886
DiseaseLeber Congenital Amaurosis

TULP1 GUCY2D

4.46e-03221342C0339527
DiseaseTesticular Germ Cell Tumor

AIFM3 UCK2 PRDM14

4.52e-03731343EFO_1000566

Protein segments in the cluster

PeptideGeneStartEntry
VDFLDTNIIITEPYF

ACTR6

86

Q9GZN1
GKAITFVTQYDVELF

DDX47

361

Q9H0S4
TTVSEYFFNDIFIEV

BDP1

2606

A6H8Y1
YEYLETVTQFGFVTL

ANO5

671

Q75V66
IALVFTDFQLEEGYD

CSMD1

246

Q96PZ7
FFQTSLHDVVEVYDG

CSMD3

1806

Q7Z407
VALATVYFQEEFLDG

CALR3

16

Q96L12
QGIFFDIYEGQITAI

ABCA10

411

Q8WWZ4
FFRAYGIEVLTEAQV

AIFM3

256

Q96NN9
VVIFSIVATDLNEYG

ABCA9

1146

Q8IUA7
EDTRILQYFVSQGFE

GOT1L1

226

Q8NHS2
GYIIQITFNDFDIEE

ADGRG6

76

Q86SQ4
VVFELGVTFNYNLAD

FABP2

61

P12104
FLLFDSESIGIYVQE

MACROH2A2

351

Q9P0M6
FVLFDSESIGIYVQE

MACROH2A1

351

O75367
EIINGDTDTFIVDRY

FAT4

1566

Q6V0I7
AEDDVVFYLVFLGST

AKAP13

26

Q12802
ITATVTFQEFRYDEF

ANKRD13C

506

Q8N6S4
VYSQEVITVLGEIDF

ALDH3A2

56

P51648
VFQVVYTESTIDFLD

CCM2

216

Q9BSQ5
GEYFIFDSKTVSIEE

DIAPH2

976

O60879
AEEGYGVELVFQTFE

BMP1

896

P13497
FEIDESTGLIITVNY

CDH23

1256

Q9H251
FSESGINYEIIIIDD

DPM1

51

O60762
TLVQGEENFSEVYGF

ADAMTS20

1756

P59510
FYIFDVLDQDGNIVS

CPT2

251

P23786
AQAYAERLGVTFFEV

RAB40A

141

Q8WXH6
AQAYAERLGVTFFEV

RAB40B

141

Q12829
AQAYAERLGVTFFEV

RAB40AL

141

P0C0E4
FVRIEDFIQFATVYG

RAB11FIP3

221

O75154
AVAQYALFLESVTEF

NUP107

601

P57740
IYVLGSEVEITDAFN

KBTBD3

456

Q8NAB2
QTESLVRGFYEVVDA

HECW2

1421

Q9P2P5
QILYSVFEEQEEGSV

PCDHGA4

61

Q9Y5G9
EEVTVGKFYATFLIQ

CACNA1F

1576

O60840
DSYTQEVVIIVFALF

OR9Q2

191

Q8NGE9
LAFEIIDQYFSGDDI

KPNA3

476

O00505
EYILGNDFTDLFDIV

NT5DC1

231

Q5TFE4
GVILFSSAVYFAEAE

KCNA1

336

Q09470
FEQVTLYFSDIVGFT

GUCY2D

876

Q02846
VGAEVAYFVEFLQSA

PNLIP

141

P16233
IYGFEILEDNSFEQF

MYO1A

381

Q9UBC5
LVSVESGFVTNDIYE

LAYN

346

Q6UX15
FLAYVELLDEVEQGS

EXD1

6

Q8NHP7
VSFHGDVTVYLFDQE

LMTK3

1351

Q96Q04
SFVVEDIATGVQTLY

DDX58

891

O95786
VFFGYHVLSDVVSVE

DUOX2

106

Q9NRD8
VENIFYVSFIVRDGF

EID3

256

Q8N140
GFITTEVVNELYVDD

ERGIC1

46

Q969X5
VGTDVRQVFEYDLIS

MYOC

291

Q99972
VYNFEFEDLQVTFRG

LACC1

126

Q8IV20
FVFAEVNSDLIYITA

F13A1

431

P00488
RSVLEDFFTATEGQY

LCK

491

P06239
SVVYREGANDFVVTF

IL7R

136

P16871
QATYEDFVEGLRVFD

MYL1

126

P05976
YVTRSENSIFFEVDG

POLE

921

Q07864
GNEVYHIVLEESTFF

KCNT2

486

Q6UVM3
ETYGFIQVTLLDTIE

PTPRS

1511

Q13332
SLTIQFVEGQFVDSY

RHEB

21

Q15382
NVPIDIFADEISFYE

KCNA10

156

Q16322
IVNFLDSYLVGDELF

PAK2

306

Q13177
DNELIAEVILYSEGF

DYNC2H1

1821

Q8NCM8
IFISYLENYIEVETG

EXOC5

341

O00471
VISSIVFGDRFDYED

CYP2A13

181

Q16696
IAALEQTAYFIGIFT

ARV1

146

Q9H2C2
DEVTVGKFYATFLIQ

CACNA1S

1516

Q13698
SEEDFSIYSRFVQLG

FIG4

811

Q92562
VISSIVFGDRFDYED

CYP2A7

181

P20853
TNLIIFGERFTYEDT

CYP2R1

191

Q6VVX0
QQYGSETEGVFVITF

DIS3L

171

Q8TF46
ETEGVFVITFKNYLD

DIS3L

176

Q8TF46
AGVATFVLQEEFDRY

DPP8

266

Q6V1X1
IISTDEGAFAYIVNY

CLCN5

196

P51795
DIYFLNITATDGLFV

FAT3

2996

Q8TDW7
PTFTFGETEVYDQVL

AWAT1

216

Q58HT5
GRVDQVSEFEYDLFI

AGBL4

56

Q5VU57
VDLEVTLEEVYAGNF

DNAJB11

136

Q9UBS4
QAEYEFISSGLYLVV

MARCHF7

631

Q9H992
YEQLFVSPEVFVTLG

MC4R

41

P32245
TYGFLVVANNETEEI

FGL2

16

Q14314
TFITEDQARYAGDII

DDX46

721

Q7L014
LEEFSVYGNIVYASV

COCH

56

O43405
YDFFIVSQSVQDGTV

PIWIL3

796

Q7Z3Z3
EYVFLISELAGEQRF

SBNO1

991

A3KN83
EVFQTDTIEYGEILS

SLFN13

191

Q68D06
VYSREGEFTVEVLAF

PKD1L1

641

Q8TDX9
EIFFITNDVTDVTFG

HELB

836

Q8NG08
GFDVVFNYKTVESLE

PTGR1

186

Q14914
DIFVGNTTLIDEDVY

FIBP

6

O43427
VTLVGQVFESYVSEY

MCM9

6

Q9NXL9
YFEQFFETVGISLAN

CARS2

456

Q9HA77
VIEFEYAESINEGLL

GFM2

606

Q969S9
QFTEEDLHFVLYGVT

PRDM14

196

Q9GZV8
TIVFTEEFEHVGYLV

SLC9C1

606

Q4G0N8
VGNFKFIYVDVISEE

SAMSN1

211

Q9NSI8
EEDYLNFILFSGDVS

ITIH3

316

Q06033
DAVTVVLYNVFESFV

SLC9A3

221

P48764
NEYFLVGVTEELEDF

HS2ST1

246

Q7LGA3
YETSVVAQFGIKDVF

RHOBTB2

186

Q9BYZ6
LDIAGFEIFEYNSLE

MYH3

461

P11055
ETGLFYVDEIIIADT

PKHD1

696

P08F94
YVDTGFVNTDDLIIT

SLCO1A2

221

P46721
VVYGVFSIAEFFSDI

REEP5

91

Q00765
AINYVATEVFREELG

ITGAL

236

P20701
LEVTELETQFADGVY

PARVA

281

Q9NVD7
FAVFGLQVYDETEVS

SPAG4

356

Q9NPE6
VTFQQYFLDVSELEG

SPTBN5

1626

Q9NRC6
AEIAESVQAFVVYFD

AAGAB

71

Q6PD74
ISLQEVETEQYFTLF

CNOT6L

236

Q96LI5
FFVITVTAIKQGYED

ATP11A

101

P98196
NFLYATDVVEAFLTV

TGDS

231

O95455
YIVLQFGRVAEDAFT

TULP1

501

O00294
SIEQVYFSVDSFDIV

VPS50

56

Q96JG6
FVEDQAVVETVFFLT

ZSWIM9

201

Q86XI8
VEFLQTVANVFLEAY

VPS13A

1511

Q96RL7
IAYYIEGIENSVFTL

VPS13A

2121

Q96RL7
ELSVTYGESFQVIIE

UNC13C

1841

Q8NB66
VLFTYFQGDISSVVD

VGLL2

86

Q8N8G2
STEIVFITDQGIEFY

RMC1

121

Q96DM3
VGEDSTYKFFEVILI

RPL15

121

P61313
FAYVTEFVDLGNVSA

SCN2A

201

Q99250
FQAFFEEIGIEYSVL

ZBED8

311

Q8IZ13
YRISLQFEVFELEGN

TLL2

656

Q9Y6L7
GLFVEYETDQTVLEQ

RHAG

21

Q02094
IYEFVAGVSATLNYE

VWA5A

26

O00534
VVLFEGILAFYSQEV

UCK2

131

Q9BZX2
IVSQFETEFYISGLA

VPS41

261

P49754
GRVVFEDVAIYFSQE

ZNF548

6

Q8NEK5
YTFADIIFGNEQIIS

TRAPPC8

1176

Q9Y2L5
VDFQEYAVFLALITV

S100A2

71

P29034
FHIVFSEEFEYTGQI

SLC9C2

601

Q5TAH2
YLGPVTFEDVAVLFT

ZNF589

31

Q86UQ0
ELDIGDATQVYVAFL

TSEN15

51

Q8WW01
VPVTFVDIAVYFSED

ZNF282

196

Q9UDV7
VIFYSEIGSEEFSNF

UGGT1

196

Q9NYU2
NIISDIGYFESVFVR

VPS13D

1246

Q5THJ4
LAYVEGFQEDLNTTF

GEMIN4

516

P57678
VGVQDFVLLDAYTSE

MYO1H

11

Q8N1T3
LDIYGFETFEINSFE

MYO5A

436

Q9Y4I1
VLDIYGFETFEVNSF

MYO5B

436

Q9ULV0