Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

KIF21B CACNB2 MYH11 SYNE1 SPTAN1 NUMA1 GAS8 ENKD1 TUBGCP6 SPTBN4 SPTBN5 SETD2 NF2 RACGAP1 CEP295 PLEC TNNT1 ALDOB NEXN MTUS2 HCLS1 CAP2 CFAP157

1.38e-07109912023GO:0008092
GeneOntologyMolecularFunctionactin filament binding

CACNB2 MYH11 SYNE1 SPTAN1 SPTBN4 SPTBN5 PLEC NEXN HCLS1

9.48e-062271209GO:0051015
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF21B NSF ATP9B MORC4 DDX55 RAD50 ATP11B DDX23 ATP2B2 ATP2B3 PIF1 RAD17

1.42e-0544112012GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

KIF21B MRE11 MYH11 NSF ATP9B MORC4 DDX55 RAD50 ATP11B DDX23 ATP2B2 ATP2B3 PIF1 RAD17

1.95e-0561412014GO:0140657
GeneOntologyMolecularFunctionmicrotubule binding

KIF21B NUMA1 GAS8 ENKD1 TUBGCP6 RACGAP1 CEP295 MTUS2 CFAP157

1.03e-043081209GO:0008017
GeneOntologyMolecularFunctioniron-responsive element binding

ACO1 IREB2

1.07e-0431202GO:0030350
GeneOntologyMolecularFunctionaconitate hydratase activity

ACO1 IREB2

1.07e-0431202GO:0003994
GeneOntologyMolecularFunctionactin binding

CACNB2 MYH11 SYNE1 SPTAN1 SPTBN4 SPTBN5 NF2 PLEC NEXN HCLS1 CAP2

1.49e-0447912011GO:0003779
GeneOntologyMolecularFunctiontubulin binding

KIF21B NUMA1 GAS8 ENKD1 TUBGCP6 SETD2 RACGAP1 CEP295 MTUS2 CFAP157

2.63e-0442812010GO:0015631
GeneOntologyMolecularFunctionhistone deacetylase regulator activity

NCOR1 UCN

7.37e-0471202GO:0035033
GeneOntologyMolecularFunctionprotein domain specific binding

CACNB2 NSF NUMA1 ADAM12 TFDP1 ELMO1 TFDP2 THAP7 NCOR1 NF2 GPSM2 ATP2B2 ATP2B3 HCLS1

7.79e-0487512014GO:0019904
GeneOntologyMolecularFunctionspectrin binding

SPTAN1 SPTBN4 SPTBN5

1.11e-03341203GO:0030507
GeneOntologyMolecularFunctionpyrophosphatase activity

KIF21B CILP NSF ATP9B MORC4 DDX55 RAD50 ATP11B DDX23 ATP2B2 ATP2B3 PIF1 RAD17

1.61e-0383912013GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

KIF21B CILP NSF ATP9B MORC4 DDX55 RAD50 ATP11B DDX23 ATP2B2 ATP2B3 PIF1 RAD17

1.63e-0384012013GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

KIF21B CILP NSF ATP9B MORC4 DDX55 RAD50 ATP11B DDX23 ATP2B2 ATP2B3 PIF1 RAD17

1.63e-0384012013GO:0016818
GeneOntologyBiologicalProcessR-loop processing

MRE11 RAD50 DDX23

1.53e-0591193GO:0062176
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

MNS1 NUMA1 GAS8 ENKD1 TUBGCP6 NCOR1 SETD2 MAP7D1 RACGAP1 GPSM2 CFAP74 CEP295 PARD3 CFAP157

7.04e-0572011914GO:0000226
GeneOntologyBiologicalProcessactin filament-based process

CDC42BPG CACNB2 MYH11 SPTAN1 ARHGEF18 CDC42BPB ELMO1 SPTBN4 SPTBN5 NF2 RACGAP1 PLEC PARD3 TNNT1 HCLS1 CAP2

7.04e-0591211916GO:0030029
GeneOntologyBiologicalProcessactomyosin structure organization

CDC42BPG MYH11 ARHGEF18 CDC42BPB NF2 RACGAP1 PLEC TNNT1

7.51e-052391198GO:0031032
GeneOntologyBiologicalProcessorganelle assembly

MYH11 MNS1 SYNE1 NUMA1 GAS8 ENKD1 TUBGCP6 NCOR1 NF2 RACGAP1 GPSM2 CFAP74 CEP295 PLEC TNNT1 CFAP53 ATG16L2 CFAP157

9.09e-05113811918GO:0070925
GeneOntologyBiologicalProcessmicrotubule-based process

KIF21B MNS1 NUMA1 GAS8 ENKD1 TUBGCP6 NCOR1 SETD2 MAP7D1 CFAP45 RACGAP1 GPSM2 CFAP74 CEP295 PARD3 CFAP53 CFAP157

1.20e-04105811917GO:0007017
GeneOntologyCellularComponentspindle

NUMA1 MBIP ENKD1 TFDP2 TUBGCP6 NCOR1 MAP7D1 RACGAP1 GPSM2 CEP295 PARD3 CFAP53 TBL1X

2.92e-0647111913GO:0005819
GeneOntologyCellularComponentcortical cytoskeleton

SPTAN1 NUMA1 SPTBN4 SPTBN5 NF2 FLOT1 HCLS1

9.14e-061291197GO:0030863
GeneOntologyCellularComponentsupramolecular fiber

KIF21B MYH11 MNS1 SYNE1 SPTAN1 NUMA1 GAS8 ENKD1 PPL TUBGCP6 SPTBN4 CFAP45 RACGAP1 CEP295 PLEC TNNT1 NEXN CFAP53 MTUS2 HCLS1

1.06e-05117911920GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KIF21B MYH11 MNS1 SYNE1 SPTAN1 NUMA1 GAS8 ENKD1 PPL TUBGCP6 SPTBN4 CFAP45 RACGAP1 CEP295 PLEC TNNT1 NEXN CFAP53 MTUS2 HCLS1

1.17e-05118711920GO:0099081
GeneOntologyCellularComponentspectrin

SPTAN1 SPTBN4 SPTBN5

1.47e-0591193GO:0008091
GeneOntologyCellularComponentcortical actin cytoskeleton

SPTAN1 SPTBN4 SPTBN5 NF2 FLOT1 HCLS1

1.53e-05931196GO:0030864
GeneOntologyCellularComponentmitotic spindle

NUMA1 MBIP TFDP2 NCOR1 RACGAP1 GPSM2 CEP295 TBL1X

2.00e-052011198GO:0072686
GeneOntologyCellularComponentlateral cell cortex

NUMA1 GPSM2

3.21e-0521192GO:0097575
GeneOntologyCellularComponentmicrotubule organizing center

CDC42BPG NUMA1 GAS8 TSGA10 ANKRD26 ANKRD62 CCDC178 ENKD1 TUBGCP6 GPSM2 CEP295 FLOT1 ALDOB CFAP53 MTUS2 CFAP157

6.59e-0591911916GO:0005815
GeneOntologyCellularComponentactin cytoskeleton

MYH11 SPTAN1 ANKRD26 ANKRD62 CDC42BPB SPTBN4 SPTBN5 NF2 TNNT1 FLOT1 NEXN HCLS1

1.11e-0457611912GO:0015629
GeneOntologyCellularComponentcytoplasmic microtubule

MNS1 NUMA1 ENKD1 CFAP45 CFAP53 MTUS2

1.14e-041331196GO:0005881
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KIF21B MNS1 NUMA1 GAS8 ENKD1 PPL TUBGCP6 SPTBN4 CFAP45 RACGAP1 CEP295 PLEC CFAP53 MTUS2 HCLS1

1.81e-0489911915GO:0099513
GeneOntologyCellularComponentmicrotubule

KIF21B MNS1 NUMA1 GAS8 ENKD1 TUBGCP6 CFAP45 RACGAP1 CEP295 CFAP53 MTUS2

2.36e-0453311911GO:0005874
GeneOntologyCellularComponentcell cortex

SPTAN1 NUMA1 SPTBN4 SPTBN5 NF2 GPSM2 PARD3 FLOT1 HCLS1

2.76e-043711199GO:0005938
GeneOntologyCellularComponentMre11 complex

MRE11 RAD50

3.18e-0451192GO:0030870
GeneOntologyCellularComponent9+0 motile cilium

CFAP45 CFAP53

4.75e-0461192GO:0097728
GeneOntologyCellularComponentBRCA1-C complex

MRE11 RAD50

4.75e-0461192GO:0070533
GeneOntologyCellularComponentlateral part of cell

NUMA1 GPSM2

8.80e-0481192GO:0097574
GeneOntologyCellularComponentcytoplasmic region

MNS1 NUMA1 GAS8 SPTBN5 CFAP45 GPSM2 CFAP74 CFAP53

1.07e-033601198GO:0099568
GeneOntologyCellularComponentaxoneme

MNS1 GAS8 SPTBN5 CFAP45 CFAP74 CFAP53

1.20e-032071196GO:0005930
GeneOntologyCellularComponentciliary plasm

MNS1 GAS8 SPTBN5 CFAP45 CFAP74 CFAP53

1.23e-032081196GO:0097014
GeneOntologyCellularComponentpresynaptic active zone

TRIO PHB1 P2RX1 FLOT1 ATP2B2

1.28e-031411195GO:0048786
GeneOntologyCellularComponentcentrosome

CDC42BPG NUMA1 ANKRD26 ANKRD62 ENKD1 TUBGCP6 GPSM2 CEP295 FLOT1 ALDOB CFAP53 MTUS2

1.48e-0377011912GO:0005813
GeneOntologyCellularComponentmain axon

SPTAN1 SPTBN4 UCN PARD3

1.68e-03891194GO:0044304
GeneOntologyCellularComponentparallel fiber to Purkinje cell synapse

CADPS2 ATP2B2 ATP2B3

1.88e-03431193GO:0098688
GeneOntologyCellularComponentcell cortex region

NUMA1 SPTBN5 GPSM2

2.14e-03451193GO:0099738
GeneOntologyCellularComponentspliceosomal snRNP complex

SART3 PRPF40A PRPF40B DDX23

2.22e-03961194GO:0097525
GeneOntologyCellularComponentaxonemal microtubule doublet inner sheath

MNS1 CFAP45 CFAP53

2.28e-03461193GO:0160110
GeneOntologyCellularComponentglutamatergic synapse

KIF21B TRIO SPTAN1 CRTAC1 ELMO1 PHB1 P2RX1 NRG3 CADPS2 FLOT1 ATP2B2 ATP2B3

2.42e-0381711912GO:0098978
GeneOntologyCellularComponentA axonemal microtubule

MNS1 CFAP45 CFAP53

2.43e-03471193GO:0097649
GeneOntologyCellularComponent9+2 motile cilium

MNS1 GAS8 TSGA10 CFAP45 CFAP74 CFAP53

2.44e-032381196GO:0097729
GeneOntologyCellularComponentaxonemal doublet microtubule

MNS1 CFAP45 CFAP53

2.74e-03491193GO:0097545
GeneOntologyCellularComponentsmall nuclear ribonucleoprotein complex

SART3 PRPF40A PRPF40B DDX23

3.28e-031071194GO:0030532
GeneOntologyCellularComponentparanode region of axon

SPTAN1 SPTBN4

4.13e-03171192GO:0033270
GeneOntologyCellularComponentU2-type prespliceosome

PRPF40A PRPF40B

4.63e-03181192GO:0071004
GeneOntologyCellularComponentprespliceosome

PRPF40A PRPF40B

4.63e-03181192GO:0071010
GeneOntologyCellularComponentphotoreceptor ribbon synapse

CACNB2 ATP2B2

4.63e-03181192GO:0098684
GeneOntologyCellularComponentaxonemal microtubule

MNS1 CFAP45 CFAP53

4.64e-03591193GO:0005879
GeneOntologyCellularComponentSm-like protein family complex

SART3 PRPF40A PRPF40B DDX23

4.79e-031191194GO:0120114
DomainSpectrin_repeat

TRIO SYNE1 SPTAN1 PPL SPTBN4 SPTBN5 PLEC

4.40e-10291177IPR002017
DomainSPEC

TRIO SYNE1 SPTAN1 PPL SPTBN4 SPTBN5 PLEC

9.34e-10321177SM00150
DomainSpectrin/alpha-actinin

TRIO SYNE1 SPTAN1 PPL SPTBN4 SPTBN5 PLEC

9.34e-10321177IPR018159
DomainSpectrin

TRIO SYNE1 SPTAN1 SPTBN4 SPTBN5

2.72e-07231175PF00435
DomainACTININ_2

SYNE1 SPTBN4 SPTBN5 PLEC

1.18e-05231174PS00020
DomainACTININ_1

SYNE1 SPTBN4 SPTBN5 PLEC

1.18e-05231174PS00019
DomainActinin_actin-bd_CS

SYNE1 SPTBN4 SPTBN5 PLEC

1.18e-05231174IPR001589
DomainAconitase/IRP2

ACO1 IREB2

3.89e-0521172IPR006249
DomainATPase_P-typ_cyto_domN

ATP9B ATP11B ATP2B2 ATP2B3

6.59e-05351174IPR023299
DomainATPase_P-typ_P_site

ATP9B ATP11B ATP2B2 ATP2B3

7.38e-05361174IPR018303
DomainP_typ_ATPase

ATP9B ATP11B ATP2B2 ATP2B3

7.38e-05361174IPR001757
DomainATPASE_E1_E2

ATP9B ATP11B ATP2B2 ATP2B3

7.38e-05361174PS00154
DomainATPase_P-typ_transduc_dom_A

ATP9B ATP11B ATP2B2 ATP2B3

8.23e-05371174IPR008250
DomainE1-E2_ATPase

ATP9B ATP11B ATP2B2 ATP2B3

8.23e-05371174PF00122
DomainAconitaseA/IPMdHydase_ssu_swvl

ACO1 IREB2

1.16e-0431172IPR000573
DomainDP

TFDP1 TFDP2

1.16e-0431172PF08781
DomainAconitase_C

ACO1 IREB2

1.16e-0431172PF00694
Domain-

ACO1 IREB2

1.16e-04311723.30.499.10
DomainAcoase/IPM_deHydtase_lsu_aba

ACO1 IREB2

1.16e-0431172IPR001030
DomainTranscrpt_fac_DP

TFDP1 TFDP2

1.16e-0431172IPR015648
Domain-

ACO1 IREB2

1.16e-04311723.40.1060.10
DomainTransc_factor_DP_C

TFDP1 TFDP2

1.16e-0431172IPR014889
Domain-

ACO1 IREB2

1.16e-04311723.20.19.10
DomainAcoase/IPM_deHydtase

ACO1 IREB2

1.16e-0431172IPR015937
DomainAcnase/IPM_dHydase_lsu_aba_1/3

ACO1 IREB2

1.16e-0431172IPR015931
DomainAconitase/IPMdHydase_lsu_aba_2

ACO1 IREB2

1.16e-0431172IPR015932
DomainACONITASE_1

ACO1 IREB2

1.16e-0431172PS00450
DomainAconitase/3IPM_dehydase_swvl

ACO1 IREB2

1.16e-0431172IPR015928
DomainAconitase

ACO1 IREB2

1.16e-0431172PF00330
DomainAconitase_4Fe-4S_BS

ACO1 IREB2

1.16e-0431172IPR018136
DomainACONITASE_2

ACO1 IREB2

1.16e-0431172PS01244
DomainDP

TFDP1 TFDP2

1.16e-0431172SM01138
Domain-

PRPF40A PRPF40B

2.32e-04411721.10.10.440
DomainATP_Ca_trans_C

ATP2B2 ATP2B3

2.32e-0441172IPR022141
DomainMyotonic_dystrophy_kinase_coil

CDC42BPG CDC42BPB

2.32e-0441172IPR014930
DomainATP_Ca_trans_C

ATP2B2 ATP2B3

2.32e-0441172PF12424
DomainMyotonic_dystrophy_kinase_coil

CDC42BPG CDC42BPB

2.32e-0441172PD011252
DomainP-type_ATPase_IIB

ATP2B2 ATP2B3

2.32e-0441172IPR006408
DomainDMPK_coil

CDC42BPG CDC42BPB

2.32e-0441172PF08826
DomainPH

CDC42BPG TRIO ARHGEF18 CDC42BPB ELMO1 SPTBN4 SPTBN5 CADPS2

3.66e-042781178SM00233
DomainPH_DOMAIN

CDC42BPG TRIO ARHGEF18 CDC42BPB ELMO1 SPTBN4 SPTBN5 CADPS2

3.75e-042791178PS50003
DomainPH_domain

CDC42BPG TRIO ARHGEF18 CDC42BPB ELMO1 SPTBN4 SPTBN5 CADPS2

3.84e-042801178IPR001849
DomainFF_domain

PRPF40A PRPF40B

5.74e-0461172IPR002713
DomainFF

PRPF40A PRPF40B

5.74e-0461172PS51676
DomainFF

PRPF40A PRPF40B

5.74e-0461172PF01846
DomainFF

PRPF40A PRPF40B

5.74e-0461172SM00441
DomainPH

CDC42BPG TRIO ARHGEF18 CDC42BPB SPTBN4 SPTBN5 CADPS2

6.02e-042291177PF00169
DomainCH

SYNE1 SPTBN4 SPTBN5 PLEC

7.38e-04651174SM00033
Domain-

CDC42BPG TRIO ARHGEF18 CDC42BPB ELMO1 SPTBN4 SPTBN5 NF2 CADPS2

7.96e-0439111792.30.29.30
DomainPlectin

PPL PLEC

8.00e-0471172PF00681
DomainPlectin_repeat

PPL PLEC

8.00e-0471172IPR001101
DomainPLEC

PPL PLEC

8.00e-0471172SM00250
DomainCH

SYNE1 SPTBN4 SPTBN5 PLEC

9.75e-04701174PF00307
Domain-

SYNE1 SPTBN4 SPTBN5 PLEC

1.03e-037111741.10.418.10
Domain-

ATP9B ATP11B ATP2B2

1.04e-033211733.40.1110.10
Domain-

ATP9B ATP11B ATP2B2

1.04e-033211732.70.150.10
DomainCH

SYNE1 SPTBN4 SPTBN5 PLEC

1.14e-03731174PS50021
DomainCH-domain

SYNE1 SPTBN4 SPTBN5 PLEC

1.26e-03751174IPR001715
DomainPH_dom-spectrin-type

SPTBN4 SPTBN5

1.36e-0391172IPR001605
DomainPH_dom-like

CDC42BPG TRIO ARHGEF18 CDC42BPB ELMO1 SPTBN4 SPTBN5 NF2 CADPS2

1.45e-034261179IPR011993
DomainHAD-like_dom

ATP9B ATP11B ATP2B2 ATP2B3

1.53e-03791174IPR023214
DomainHydrolase_3

ATP2B2 ATP2B3

1.69e-03101172PF08282
DomainE2F_TDP

TFDP1 TFDP2

2.06e-03111172PF02319
DomainBand_7

PHB1 FLOT1

2.06e-03111172IPR001107
DomainBand_7

PHB1 FLOT1

2.06e-03111172PF01145
DomainE2F_TDP

TFDP1 TFDP2

2.06e-03111172SM01372
DomainE2F_WHTH_DNA-bd_dom

TFDP1 TFDP2

2.06e-03111172IPR003316
DomainPHB

PHB1 FLOT1

2.06e-03111172SM00244
Domain-

DUS3L MYORG ALDOB

2.30e-034211733.20.20.70
DomainGRIP_dom

TRIP11 GOLGA1

2.46e-03121172IPR000237
DomainGRIP

TRIP11 GOLGA1

2.46e-03121172PS50913
DomainAldolase_TIM

DUS3L MYORG ALDOB

2.63e-03441173IPR013785
DomainWW

PRPF40A SETD2 PRPF40B

3.18e-03471173PF00397
DomainP_typ_ATPase_c

ATP9B ATP11B

3.37e-03141172IPR032630
DomainP-type_ATPase_N

ATP9B ATP11B

3.37e-03141172IPR032631
DomainP-type_ATPase_IV

ATP9B ATP11B

3.37e-03141172IPR006539
DomainPhoLip_ATPase_C

ATP9B ATP11B

3.37e-03141172PF16212
DomainPhoLip_ATPase_N

ATP9B ATP11B

3.37e-03141172PF16209
DomainCNH

CDC42BPG CDC42BPB

3.37e-03141172SM00036
DomainWW

PRPF40A SETD2 PRPF40B

3.38e-03481173SM00456
DomainSH3_1

CACNB2 TRIO SPTAN1 MAP3K10 HCLS1

3.73e-031641175PF00018
DomainCNH

CDC42BPG CDC42BPB

3.87e-03151172PF00780
DomainCNH

CDC42BPG CDC42BPB

3.87e-03151172PS50219
DomainCNH_dom

CDC42BPG CDC42BPB

3.87e-03151172IPR001180
DomainWW_DOMAIN_1

PRPF40A SETD2 PRPF40B

4.01e-03511173PS01159
DomainWW_DOMAIN_2

PRPF40A SETD2 PRPF40B

4.01e-03511173PS50020
DomainWW_dom

PRPF40A SETD2 PRPF40B

4.24e-03521173IPR001202
DomainATPase_P-typ_TM_dom

ATP2B2 ATP2B3

4.41e-03161172IPR023298
Domain-

ATP2B2 ATP2B3

4.41e-031611721.20.1110.10
DomainATPase_P-typ_cation-transptr_C

ATP2B2 ATP2B3

4.98e-03171172IPR006068
DomainCation_ATPase_C

ATP2B2 ATP2B3

4.98e-03171172PF00689
DomainPBD

CDC42BPG CDC42BPB

4.98e-03171172PF00786
DomainC1_1

CDC42BPG CDC42BPB RACGAP1

5.48e-03571173PF00130
DomainCation_ATPase_N

ATP2B2 ATP2B3

5.58e-03181172PF00690
DomainCation_ATPase_N

ATP2B2 ATP2B3

5.58e-03181172SM00831
DomainATPase_P-typ_cation-transptr_N

ATP2B2 ATP2B3

6.21e-03191172IPR004014
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SPTAN1 SPTBN4 SPTBN5

3.12e-0510923MM15112
PathwayBIOCARTA_ATRBRCA_PATHWAY

MRE11 RAD50 RAD17

2.42e-0419923MM1478
PathwayWP_ECTODERM_DIFFERENTIATION

NUMA1 MYORG NF2 UBTF CAP2 TBL1X

3.29e-04142926M39575
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

ARHGEF18 TFDP1 TFDP2 NCOR1 PARD3

3.69e-0494925M1041
PathwayBIOCARTA_ATRBRCA_PATHWAY

MRE11 RAD50 RAD17

3.79e-0422923M9703
PathwayREACTOME_ACTIVATION_OF_NOXA_AND_TRANSLOCATION_TO_MITOCHONDRIA

TFDP1 TFDP2

4.16e-045922M26903
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP9B ATP11B ATP2B2 ATP2B3

4.49e-0455924M971
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP9B ATP11B ATP2B2 ATP2B3

5.15e-0457924MM15643
PathwayREACTOME_COPI_MEDIATED_ANTEROGRADE_TRANSPORT

NSF SPTAN1 SPTBN4 SPTBN5 COG5

5.37e-04102925M27648
PathwayREACTOME_SENSING_OF_DNA_DOUBLE_STRAND_BREAKS

MRE11 RAD50

6.21e-046922M27585
PathwayREACTOME_SENSING_OF_DNA_DOUBLE_STRAND_BREAKS

MRE11 RAD50

6.21e-046922MM15295
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

P2RX1 ATP2B2 ATP2B3

7.02e-0427923MM15053
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

CACNB2 SPTAN1 SPTBN4 SPTBN5

7.54e-0463924M11187
PathwayREACTOME_COPI_MEDIATED_ANTEROGRADE_TRANSPORT

NSF SPTAN1 SPTBN4 SPTBN5 COG5

7.57e-04110925MM15350
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

P2RX1 ATP2B2 ATP2B3

7.83e-0428923M924
PathwayWP_NONHOMOLOGOUS_END_JOINING

MRE11 RAD50

8.66e-047922MM15989
PathwayREACTOME_LOSS_OF_MECP2_BINDING_ABILITY_TO_THE_NCOR_SMRT_COMPLEX

NCOR1 TBL1X

8.66e-047922M27899
PathwayWP_DDX1_AS_A_REGULATORY_COMPONENT_OF_THE_DROSHA_MICROPROCESSOR

MRE11 RAD50

8.66e-047922M39689
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

MYH11 TRIO SPTAN1 ANKRD26 ANKRD62 ARHGEF18 CDC42BPB ZWINT FAM13A NF2 RACGAP1 FLOT1

1.02e-036499212MM15690
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SPTAN1 SPTBN4 SPTBN5

1.06e-0331923M877
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SART3 FAM184B MYH11 SYNE1 SPTAN1 NUMA1 ANKRD26 CCDC150 HKDC1 DDX55 PPL PHB1 SPTBN4 NCOR1 MAP7D1 CFAP45 NFXL1 DDX23 CFAP74 CEP295 PLEC CADPS2 TNNT1 KIAA2012 ATP2B2 ATP2B3 HCLS1

7.37e-1314421222735575683
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TRIO ACO1 SYNE1 SPTAN1 CRTAC1 KPNA6 TRIP11 CDC42BPB SPTBN4 RNF123 NF2 MAP3K10 GPSM2 ANKRD36 PLEC CADPS2 CARS2 FLOT1 ZNHIT1 MTUS2 CAP2 DOP1B

7.12e-1012851222235914814
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KIF21B CACNB2 TRIO NSF SYNE1 SPTAN1 NUMA1 ARHGEF18 TRIP11 CDC42BPB RAD50 SPTBN4 NCOR1 MAP7D1 RACGAP1 PARD3 GOLGA1 CAP2 TBL1X

1.19e-099631221928671696
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

KIF21B MRE11 NSF SPTAN1 CD109 NUMA1 KPNA6 PRPF40A NF2 UBTF GOLGA7 RACGAP1 DDX23 PLEC FLOT1

1.21e-086601221532780723
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

TRIO ACO1 SYNE1 ANKRD26 TNIP1 TRIP11 CDC42BPB NCOR1 MAP7D1 NF2 PLEC PARD3 TNNT1

2.37e-084971221323414517
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TRIO SPTAN1 RAB11FIP2 ANKRD26 GIGYF1 STK32C TRIP11 ENKD1 MAP7D1 FAM13A MAP3K10 RACGAP1 CRYBG3 PLEC PARD3 DOP1B

6.20e-088611221636931259
Pubmed

Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles.

NUMA1 PRPF40A NCOR1 SETD2

1.91e-0715122411092755
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

SART3 FAM184B NSF SYNE1 SPTAN1 ANKRD26 TNIP1 CDC42BPB PRPF40A TFDP1 PHB1 TUBGCP6 NF2 UBTF NFXL1 DDX23 CRYBG3 PARD3 CARS2 FLOT1

2.41e-0714871222033957083
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

SART3 UBR2 MRE11 PPP2R2D NSF TNIP1 KPNA6 TFDP1 RAD50 NCOR1 MAP7D1 NFXL1 COG5 ATP2B3 TBL1X

3.54e-078571221525609649
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MRE11 KPNA6 GIGYF1 PRPF40A ENKD1 TFDP1 TFDP2 RAD50 TUBGCP6 FCSK SETD2 MAP7D1 TCHH PRPF40B CEP295 CRYBG3 PARD3

3.88e-0711161221731753913
Pubmed

SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Gαi-LGN-NuMA Ternary Complex.

NUMA1 GPSM2 PARD3

4.19e-075122326766442
Pubmed

Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks.

MRE11 RAD50 RAD17

4.19e-075122324534091
Pubmed

Human transcription factor protein interaction networks.

MRE11 SPTAN1 NUMA1 TNIP1 GIGYF1 MORC4 MBIP PRPF40A TFDP1 TFDP2 PHB1 RAD50 NCOR1 MAP7D1 UBTF RACGAP1 FLOT1 ZNHIT1 TBL1X

5.95e-0714291221935140242
Pubmed

ANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cells.

TRIO ANKRD26 ANKRD62

8.36e-076122322666460
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

SART3 MRE11 NUMA1 PRPF40A RAD50 NCOR1 UBTF DDX23

1.17e-06220122835785414
Pubmed

A human MAP kinase interactome.

MYH11 SYNE1 SPTAN1 KPNA6 STK32C CDC42BPB ENKD1 MAP3K10 PLEC COG5 CAP2

1.23e-064861221120936779
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

MYH11 SYNE1 SPTAN1 CD109 NUMA1 TNIP1 DDX55 PRPF40A NF2 UBTF RACGAP1 DDX23 PLEC FLOT1 NEXN

1.26e-069491221536574265
Pubmed

Robust control of mitotic spindle orientation in the developing epidermis.

NUMA1 GPSM2 PARD3

1.46e-067122321098114
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

SART3 TNIP1 KPNA6 GIGYF1 TRIP11 PRPF40A PPL NCOR1 SETD2 MAP7D1 ITPRIPL1 HCLS1

1.66e-066081221216713569
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

LYRM7 SART3 KIF21B MRE11 MYH11 SPTAN1 NUMA1 HKDC1 PRPF40A PHB1 RAD50 DDX23 PLEC FLOT1

1.75e-068471221435235311
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TNIP1 MORC4 MBIP TFDP1 RAD50 NCOR1 MAP7D1 CRYBG3 PLEC TBL1X

2.35e-064181221034709266
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

SART3 PPP2R2D SYNE1 NUMA1 KPNA6 PPL ZWINT PHB1 TUBGCP6 MAP7D1 RACGAP1 DDX23 DCAF11 COG5 FLOT1 NEXN

3.00e-0611551221620360068
Pubmed

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.

NUMA1 HKDC1 KPNA6 DUS3L STK32A DDX23 CARS2

3.59e-06180122724104479
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

MRE11 SPTAN1 NUMA1 TNIP1 MBIP PRPF40A RAD50 NCOR1 SETD2 NF2 PARD3

3.97e-065491221138280479
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

KIF21B SYNE1 SPTAN1 SPTBN5 SETD2 ANKRD36 PLEC

4.62e-06187122726460568
Pubmed

Cell polarity and spindle orientation in the distal epithelium of embryonic lung.

NUMA1 GPSM2 PARD3

4.96e-0610122321246661
Pubmed

alphaII-Spectrin interacts with five groups of functionally important proteins in the nucleus.

MRE11 SPTAN1 RAD50 SPTBN4

6.16e-0634122416889989
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SART3 CACNB2 MYH11 TRIO NSF SYNE1 SPTAN1 TRIP11 CDC42BPB PRPF40A SPTBN4 MAP7D1 PLEC FLOT1 ATP2B2 ATP2B3 MTUS2

1.09e-0514311221737142655
Pubmed

alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.

SPTAN1 SPTBN4 SPTBN5

1.17e-0513122318796539
Pubmed

RAD50 regulates mitotic progression independent of DNA repair functions.

MRE11 RAD50

1.22e-052122231908056
Pubmed

Subcellular localization of iron regulatory proteins to Golgi and ER membranes.

ACO1 IREB2

1.22e-052122216144863
Pubmed

Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity.

ANKRD26 ANKRD62

1.22e-052122228266632
Pubmed

Electron tomography of degenerating neurons in mice with abnormal regulation of iron metabolism.

ACO1 IREB2

1.22e-052122215866737
Pubmed

Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions.

NUMA1 GPSM2

1.22e-052122231101817
Pubmed

A regulated RNA binding protein also possesses aconitase activity.

ACO1 IREB2

1.22e-05212221946430
Pubmed

Generation of conditional alleles of the murine Iron Regulatory Protein (IRP)-1 and -2 genes.

ACO1 IREB2

1.22e-052122216283625
Pubmed

Iron regulatory proteins 1 and 2 have opposing roles in regulating inflammation in bacterial orchitis.

ACO1 IREB2

1.22e-052122238301068
Pubmed

Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis.

ACO1 IREB2

1.22e-052122214726953
Pubmed

Effect of hypoxia on the binding and subcellular distribution of iron regulatory proteins.

ACO1 IREB2

1.22e-052122217200797
Pubmed

Decreased expression of MRE11 and RAD50 in testes from humans with spermatogenic failure.

MRE11 RAD50

1.22e-052122231983050
Pubmed

In vivo role(s) of the iron regulatory proteins (IRP) 1 and 2 in aseptic local inflammation.

ACO1 IREB2

1.22e-052122219533074
Pubmed

Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2.

ACO1 IREB2

1.22e-052122215831703
Pubmed

An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs.

NUMA1 GPSM2

1.22e-052122223665171
Pubmed

Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins.

ACO1 IREB2

1.22e-052122225771171
Pubmed

Targeted mutagenesis of the murine IRP1 and IRP2 genes reveals context-dependent RNA processing differences in vivo.

ACO1 IREB2

1.22e-052122215208438
Pubmed

Intramolecular interaction in LGN, an adaptor protein that regulates mitotic spindle orientation.

NUMA1 GPSM2

1.22e-052122231732560
Pubmed

The MRN protein complex genes: MRE11 and RAD50 and susceptibility to head and neck cancers.

MRE11 RAD50

1.22e-052122224079363
Pubmed

Characterization of a second RNA-binding protein in rodents with specificity for iron-responsive elements.

ACO1 IREB2

1.22e-05212228262972
Pubmed

Localization of two genes encoding plasma membrane Ca2+ ATPases isoforms 2 (ATP2B2) and 3 (ATP2B3) to human chromosomes 3p26-->p25 and Xq28, respectively.

ATP2B2 ATP2B3

1.22e-05212228187550
Pubmed

Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia.

MRE11 RAD50

1.22e-052122224093751
Pubmed

Localisation and function of key axonemal microtubule inner proteins and dynein docking complex members reveal extensive diversity among vertebrate motile cilia.

MNS1 CFAP53

1.22e-052122239007638
Pubmed

Iron regulatory proteins 1 and 2 in human monocytes, macrophages and duodenum: expression and regulation in hereditary hemochromatosis and iron deficiency.

ACO1 IREB2

1.22e-052122216503547
Pubmed

Iron regulatory protein 1 outcompetes iron regulatory protein 2 in regulating cellular iron homeostasis in response to nitric oxide.

ACO1 IREB2

1.22e-052122221566147
Pubmed

Self-association and ligand-induced conformational changes of iron regulatory proteins 1 and 2.

ACO1 IREB2

1.22e-052122215938636
Pubmed

Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex.

MRE11 RAD50

1.22e-052122216254336
Pubmed

Susceptibility loci in lung cancer and COPD: association of IREB2 and FAM13A with pulmonary diseases.

IREB2 FAM13A

1.22e-052122226310313
Pubmed

Iron regulatory proteins secure mitochondrial iron sufficiency and function.

ACO1 IREB2

1.22e-052122220674864
Pubmed

Excess capacity of the iron regulatory protein system.

ACO1 IREB2

1.22e-052122217604281
Pubmed

Partial inactivation of Ankrd26 causes diabetes with enhanced insulin responsiveness of adipose tissue in mice.

ANKRD26 ANKRD62

1.22e-052122221842266
Pubmed

Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair.

MRE11 RAD50

1.22e-05212228756642
Pubmed

Cloning of the cDNA encoding an RNA regulatory protein--the human iron-responsive element-binding protein.

ACO1 IREB2

1.22e-05212222172968
Pubmed

Genetic polymorphism of the iron-regulatory protein-1 and -2 genes in age-related macular degeneration.

ACO1 IREB2

1.22e-052122222331484
Pubmed

Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation.

ACO1 IREB2

1.22e-05212227983023
Pubmed

LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and Gαi/LGN/NuMA pathways.

NUMA1 GPSM2

1.22e-052122221816348
Pubmed

The Molecular Motor KIF21B Mediates Synaptic Plasticity and Fear Extinction by Terminating Rac1 Activation.

KIF21B ELMO1

1.22e-052122229949770
Pubmed

Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50.

MRE11 RAD50

1.22e-052122235987200
Pubmed

LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation.

NUMA1 GPSM2

1.22e-052122212445386
Pubmed

Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes.

MRE11 RAD50

1.22e-052122217349953
Pubmed

Iron regulatory proteins increase neuronal vulnerability to hydrogen peroxide.

ACO1 IREB2

1.22e-052122218655771
Pubmed

Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins.

GPSM2 PARD3

1.22e-052122220933426
Pubmed

Effects of iron regulatory protein regulation on iron homeostasis during hypoxia.

ACO1 IREB2

1.22e-052122212855587
Pubmed

Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo.

ACO1 IREB2

1.22e-052122215604406
Pubmed

The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation.

ACO1 IREB2

1.22e-05212228041788
Pubmed

Genetic variants in FAM13A and IREB2 are associated with the susceptibility to COPD in a Chinese rural population: a case-control study.

IREB2 FAM13A

1.22e-052122229872291
Pubmed

A novel form of ciliopathy underlies hyperphagia and obesity in Ankrd26 knockout mice.

ANKRD26 ANKRD62

1.22e-052122224633808
Pubmed

Diurnal control of iron responsive element containing mRNAs through iron regulatory proteins IRP1 and IRP2 is mediated by feeding rhythms.

ACO1 IREB2

1.22e-052122238773499
Pubmed

A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization.

NUMA1 GPSM2

1.22e-052122211781568
Pubmed

Cytolinker cross-talk: periplakin N-terminus interacts with plectin to regulate keratin organisation and epithelial migration.

PPL PLEC

1.22e-052122217662978
Pubmed

Defining the membrane proteome of NK cells.

KPNA6 DDX55 PRPF40A ELMO1 PHB1 RAD50 TUBGCP6 ZDHHC20 NCOR1 ATP11B NF2 NFXL1 COG5 FLOT1 ITPRIPL1

1.53e-0511681221519946888
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

LYRM7 UBR2 CDC42BPG CACNB2 TRIO ARHGEF18 ATP9B STK32C CDC42BPB SPTBN4 ATP11B FAM13A NF2 NRG3 PARD3 CAP2 TBL1X

1.82e-0514891221728611215
Pubmed

Huntingtin interacts with a family of WW domain proteins.

PRPF40A SETD2 PRPF40B

1.86e-051512239700202
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MRE11 SPTAN1 NUMA1 PRPF40A PPL RAD50 TUBGCP6 NCOR1 SETD2 FAM13A PLEC PARD3

1.89e-057741221215302935
Pubmed

mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.

FAM184B TFDP1 TFDP2 BMP1 RAD17

2.56e-0598122534943047
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

MRE11 FAM184B CACNB2 ARHGEF18 DUS3L NF2 UBTF NFXL1 CEP295 PLEC PARD3 COG5 NEXN RAD17

2.82e-0510841221411544199
Pubmed

Molecular genetics of successful smoking cessation: convergent genome-wide association study results.

CACNB2 TRIO CD109 ADAM12 NRG3

2.96e-05101122518519826
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SYNE1 SETD2 ASXL3 CFAP74 CEP295

3.10e-05102122511214970
Pubmed

Huntingtin regulates mammary stem cell division and differentiation.

NUMA1 GPSM2 PARD3

3.31e-0518122324749073
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

SPTAN1 SPTBN4 SPTBN5

3.31e-0518122312119179
Pubmed

Enhanced DNA damage response through RAD50 in triple negative breast cancer resistant and cancer stem-like cells contributes to chemoresistance.

MRE11 RAD50

3.65e-053122233090711
Pubmed

Genetic determinants of chronic obstructive pulmonary disease in South Indian male smokers.

IREB2 FAM13A

3.65e-053122224587150
Pubmed

Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum.

ACO1 IREB2

3.65e-053122218177727
Pubmed

Posttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery.

ACO1 IREB2

3.65e-053122219965627
Pubmed

The forkhead-associated domain of NBS1 is essential for nuclear foci formation after irradiation but not essential for hRAD50[middle dot]hMRE11[middle dot]NBS1 complex DNA repair activity.

MRE11 RAD50

3.65e-053122211062235
Pubmed

Mutation screening of Mre11 complex genes: indication of RAD50 involvement in breast and ovarian cancer susceptibility.

MRE11 RAD50

3.65e-053122214684699
Pubmed

Single-Molecule Imaging Reveals How Mre11-Rad50-Nbs1 Initiates DNA Break Repair.

MRE11 RAD50

3.65e-053122228867292
Pubmed

Haplotypic variation in MRE11, RAD50 and NBS1 and risk of non-Hodgkin's lymphoma.

MRE11 RAD50

3.65e-053122217169801
Pubmed

Plakins: a family of versatile cytolinker proteins.

PPL PLEC

3.65e-053122211854008
Pubmed

Lack of MRE11-RAD50-NBS1 (MRN) complex detection occurs frequently in low-grade epithelial ovarian cancer.

MRE11 RAD50

3.65e-053122228073364
Pubmed

Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres.

MRE11 RAD50

3.65e-053122217693401
Pubmed

Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex.

MRE11 RAD50

3.65e-053122212124628
InteractionFOXL1 interactions

NSF MORC4 PHB1 RAD50 NCOR1 MAP7D1 NFXL1 COG5 TBL1X

2.86e-061961219int:FOXL1
InteractionECT2 interactions

MYH11 SPTAN1 CD109 NUMA1 TNIP1 DUS3L TFDP2 PHB1 SPTBN4 RNF123 RACGAP1 DDX23 GPSM2 PLEC PARD3 FLOT1 NEXN DOP1B

5.75e-0688712118int:ECT2
InteractionDISC1 interactions

MNS1 TRIO SYNE1 SPTAN1 GAS8 TSGA10 TRIP11 SPTBN4 RNF123 DDX23 FLOT1 NEXN

1.07e-0542912112int:DISC1
InteractionNUPR1 interactions

KIF21B MRE11 NSF SPTAN1 CD109 NUMA1 KPNA6 PRPF40A NF2 UBTF GOLGA7 RACGAP1 DDX23 PLEC FLOT1

1.49e-0568312115int:NUPR1
InteractionTNNI1 interactions

MNS1 ENKD1 DCAF11 TNNT1 MTUS2

1.79e-05541215int:TNNI1
InteractionFAM167A interactions

CDC42BPG TNIP1 MORC4 CDC42BPB PPL ZWINT

2.47e-05961216int:FAM167A
InteractionPIBF1 interactions

RAB11FIP2 TSGA10 TNIP1 ENKD1 ATP2B2 CFAP53 GOLGA1 MTUS2

2.82e-052001218int:PIBF1
InteractionYWHAH interactions

KIF21B CDC42BPG MYH11 TRIO SPTAN1 RAB11FIP2 ANKRD26 GIGYF1 TRIP11 ENKD1 GSS MAP7D1 FAM13A MAP3K10 RACGAP1 CRYBG3 PLEC PARD3 DOP1B

3.06e-05110212119int:YWHAH
InteractionCHMP4B interactions

MYH11 SPTAN1 CD109 NUMA1 TNIP1 KPNA6 SPTBN4 RNF123 MAP7D1 NF2 UBTF RACGAP1 PLEC FLOT1 NEXN

3.07e-0572712115int:CHMP4B
InteractionTRIM66 interactions

MRE11 GIGYF1 TUBGCP6 FCSK SETD2 MAP7D1 CEP295 CRYBG3

3.37e-052051218int:TRIM66
InteractionWWTR1 interactions

MRE11 SPTAN1 NUMA1 TNIP1 MBIP PRPF40A RAD50 NCOR1 SETD2 NF2 PARD3

4.83e-0542212111int:WWTR1
InteractionBRPF3 interactions

MRE11 GIGYF1 ENKD1 RAD50 SETD2 MAP7D1 PARD3

6.51e-051661217int:BRPF3
InteractionZBTB26 interactions

GAS8 TSGA10 PPL RNF123

7.79e-05381214int:ZBTB26
InteractionDSCAM interactions

ACO1 SYNE1 CRTAC1 TRIP11 NF2 PLEC CAP2

7.85e-051711217int:DSCAM
InteractionPIF1 interactions

PPP2R2D DCAF11 PIF1

9.11e-05151213int:PIF1
InteractionCRHBP interactions

UBR2 TNIP1 UCN

9.11e-05151213int:CRHBP
InteractionCFAP161 interactions

MRE11 CCDC150 RAD50

9.11e-05151213int:CFAP161
InteractionYWHAZ interactions

CDC42BPG MYH11 PPP2R2D NSF SPTAN1 RAB11FIP2 ANKRD26 ARHGEF18 TNIP1 GIGYF1 PHB1 NCOR1 MAP7D1 FAM13A ASXL3 MAP3K10 RACGAP1 PLEC PARD3 ATP2B2

1.11e-04131912120int:YWHAZ
InteractionFAM227B interactions

FAM227B PPL RNF123

1.12e-04161213int:FAM227B
InteractionADAM7 interactions

HKDC1 ADAM12 ATP2B2 ATP2B3

1.27e-04431214int:ADAM7
InteractionSTAC3 interactions

GAS8 GIGYF1 ENKD1 ANKRD36

1.27e-04431214int:STAC3
InteractionGAL3ST2 interactions

RNF123 ATP2B2 MTUS2

1.61e-04181213int:GAL3ST2
InteractionCRYAA interactions

UBR2 PPP2R2D NSF CRTAC1 TFDP1 DCAF11 HCLS1

1.61e-041921217int:CRYAA
InteractionITSN1 interactions

SYNE1 SPTAN1 RAB11FIP2 PPL RNF123 ANKRD36 FLOT1 MTUS2

1.72e-042591218int:ITSN1
InteractionYWHAE interactions

KIF21B UBR2 MYH11 SPTAN1 RAB11FIP2 ANKRD26 TNIP1 GIGYF1 TRIP11 ENKD1 TFDP2 GSS PHB1 MAP7D1 FAM13A MAP3K10 RACGAP1 PARD3 CAP2

1.73e-04125612119int:YWHAE
InteractionLURAP1 interactions

CDC42BPG ANKRD26 TNIP1 CDC42BPB THAP7 NF2

1.79e-041371216int:LURAP1
InteractionKIF20A interactions

MYH11 SYNE1 SPTAN1 CD109 NUMA1 TRIP11 CDC42BPB PRPF40A PPL PHB1 SPTBN4 NF2 RACGAP1 CRYBG3 PLEC PARD3 FLOT1

1.82e-04105212117int:KIF20A
GeneFamilyEF-hand domain containing|Spectrins

SPTAN1 SPTBN4 SPTBN5

2.01e-0677131113
GeneFamilyTranscription factor Dp family

TFDP1 TFDP2

4.55e-053712987
GeneFamilyBRCA1 C complex|MRN complex

MRE11 RAD50

4.55e-0537121344
GeneFamilyRing finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex

MRE11 RAD50

1.51e-0457121336
GeneFamilyEF-hand domain containing|Plakins

PPL PLEC

4.19e-048712939
GeneFamilyATPases Ca2+ transporting

ATP2B2 ATP2B3

5.38e-0497121209
GeneFamilyATPase phospholipid transporting

ATP9B ATP11B

1.54e-03157121210
GeneFamilyWD repeat domain containing

KIF21B PPP2R2D DCAF11 ATG16L2 TBL1X

3.68e-03262715362
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

MOK MNS1 SYNE1 TSGA10 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

4.47e-0920012296a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MOK DPY19L2 MNS1 SYNE1 TSGA10 ANKRD26 CFAP74 CFAP157

7.36e-08197122874a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

ANKRD26 ANKRD62 DDX55 PRPF40A RAD50 CEP295 ANKRD36 NEXN

7.36e-0819712280fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MOK MNS1 SYNE1 TSGA10 CFAP45 CFAP74 CFAP53 CFAP157

7.66e-081981228ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellCiliated_cells-A-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

DPY19L2 MNS1 CCDC178 CFAP45 CFAP74 CFAP53 CFAP157

3.40e-07163122743194c6127df1ce3d29242f719645de3c11fd7c0
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

MOK TSGA10 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

7.98e-07185122730f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

DPY19L2 MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

8.88e-07188122734b11f72ca73153d02edcd09b38983ad1a504659
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

MOK MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

9.20e-071891227b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

MOK MNS1 SYNE1 CFAP45 KIAA2012 CFAP53 CFAP157

9.53e-0719012279ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MOK MNS1 SYNE1 CFAP45 KIAA2012 CFAP53 CFAP157

9.53e-071901227833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

MOK MNS1 SYNE1 CFAP45 KIAA2012 CFAP53 CFAP157

1.02e-061921227be592e661367affced9ebe80849b466e6adb3a34
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

MOK ANKRD62 KPNA6 GIGYF1 NCOR1 ANKRD36 PIF1

1.02e-0619212279cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

MOK MNS1 PPL CFAP45 CFAP74 CFAP53 CFAP157

1.02e-0619212279cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MOK MNS1 SYNE1 CFAP45 KIAA2012 CFAP53 CFAP157

1.06e-0619312270b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

MOK MNS1 SYNE1 CFAP45 KIAA2012 CFAP53 CFAP157

1.10e-061941227b4ce60c06568123008b1081d644733cb91c28f51
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MOK MNS1 SYNE1 CFAP45 KIAA2012 CFAP53 CFAP157

1.10e-0619412277a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MOK MNS1 SYNE1 TSGA10 CFAP74 KIAA2012 CFAP157

1.10e-0619412274a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCelldistal-Epithelial-Proximal_Ciliated|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MNS1 TIGD4 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.13e-061951227abe7998421dc59bdae35c0c2251c4a1ebef5e021
ToppCelldistal-Epithelial-Proximal_Ciliated-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MNS1 TIGD4 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.13e-0619512270e3f74e0877d33c11f048b9be8394596cf5c9c4c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 SPTBN4 ANKRD36 NRG3 ATP2B2 MTUS2 CAP2

1.17e-061961227676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MOK MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.17e-061961227686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MOK MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.17e-06196122767aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MOK MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.17e-061961227ca56311edc6788e032e7635fa69b1e07035202b5
ToppCellSevere_COVID-19-Epithelial-Ciliated|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

MOK MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.17e-0619612271cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MOK MNS1 SYNE1 CFAP45 CFAP74 CFAP53 CFAP157

1.17e-061961227d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MOK MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.17e-06196122769f5081e06d84ec1d9695762df801a9d0df1984b
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MOK MNS1 SYNE1 CFAP45 CFAP74 CFAP53 CFAP157

1.21e-06197122771fea4aa6ce96c7693fa94792d08770622873850
ToppCelldistal-Hematologic-Platelet/Megakaryocyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MNS1 TIGD4 SPTBN4 CFAP45 CFAP74 CFAP53 CFAP157

1.21e-061971227751ffb8792058384079ebfe94872b3525f1aea84
ToppCelldistal-Hematologic-Platelet/Megakaryocyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MNS1 TIGD4 SPTBN4 CFAP45 CFAP74 CFAP53 CFAP157

1.21e-061971227e28b1b154d9588dce07c123b36f7f01fa90a5fc1
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MOK MNS1 SYNE1 CFAP45 CFAP74 CFAP53 CFAP157

1.21e-061971227e453d085182364ca347cbcc9dc995c62c3353016
ToppCelldistal-3-Epithelial-Proximal_Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MNS1 TIGD4 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.21e-06197122715b4d1203943ce90a7083178d4a4284d9b323071
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MOK MNS1 SYNE1 CFAP45 CFAP74 CFAP53 CFAP157

1.21e-061971227d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 SPTBN4 ANKRD36 NRG3 ATP2B2 MTUS2 CAP2

1.26e-0619812276d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 SPTAN1 SPTBN4 NRG3 ATP2B2 MTUS2 CAP2

1.26e-0619812278ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

MNS1 ANKRD26 TRIP11 PRPF40A RAD50 ANKRD36 CFAP53

1.30e-06199122761b1ed2db71b96157b92b7535d1955a4033098da
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYH11 CILP SYNE1 CFAP45 NEXN NPAS4 CAP2

1.34e-0620012279169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

SYNE1 SPTBN4 ANKRD36 NRG3 ATP2B2 MTUS2 CAP2

1.34e-06200122748d801219bc771d6c7e151dc88ca4c179988de85
ToppCellSigmoid-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

CD109 TIGD4 ADAM12 TUBGCP6 RACGAP1 GPSM2 CFAP157

1.34e-0620012274e489ecf472857357d45e9f6c7a812aa48b72ebf
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MOK MNS1 TSGA10 CFAP45 CFAP74 CFAP53 CFAP157

1.34e-062001227f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

MOK MNS1 TSGA10 CFAP45 CFAP74 CFAP53 CFAP157

1.34e-062001227d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCellSigmoid-(1)_T_cell-(18)_cycling_gd_T|Sigmoid / shred on region, Cell_type, and subtype

CD109 TIGD4 ADAM12 TUBGCP6 RACGAP1 GPSM2 CFAP157

1.34e-0620012276e367abd1a4b87e20eb9095b8337723163e8bbae
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MOK MNS1 TSGA10 CFAP45 CFAP74 CFAP53 CFAP157

1.34e-062001227cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCellSigmoid-T_cell-cycling_gd_T|Sigmoid / Region, Cell class and subclass

CD109 TIGD4 ADAM12 TUBGCP6 RACGAP1 GPSM2 CFAP157

1.34e-0620012279769185abae084ffac36420c749625e679b70ca8
ToppCell10x5'-Lung-Myeloid_Monocytic-Cycling_mono|Lung / Manually curated celltypes from each tissue

CDC42BPG CCDC150 ZWINT SPTBN5 NEXN PIF1

4.58e-06156122663b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

MOK MNS1 GAS8 CFAP45 KIAA2012 CFAP53

6.77e-06167122626cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellNS-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MOK MNS1 CRTAC1 CCDC178 TCHH CFAP45

7.49e-061701226f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRTAC1 TNIP1 ADAM12 PLEC NRG3 PARD3

9.74e-061781226a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCellCiliated_cells-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MOK MNS1 CFAP45 CFAP74 CFAP53 CFAP157

1.01e-0517912260e6c22de2e3fb0ff23b3301863cf4011c5c59dff
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Deuterosomal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GAS8 TSGA10 CFAP45 CFAP74 CFAP53 CFAP157

1.11e-051821226000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

SYNE1 CRTAC1 MBIP BMP1 PARD3 CADPS2

1.14e-0518312268e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MBIP PPL STK32A BMP1 FAM13A CADPS2

1.18e-051841226ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DPY19L2 MNS1 CFAP45 CFAP74 KIAA2012 CFAP157

1.18e-0518412265daff849625f2f41d56615569c0ed59cd733b34c
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MOK CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.21e-051851226f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

MOK CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.21e-05185122618a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MOK MNS1 CFAP45 CFAP74 CFAP53 CFAP157

1.25e-05186122676033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MOK MNS1 CFAP45 CFAP74 CFAP53 CFAP157

1.29e-0518712262b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellCiliated_cells-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.29e-0518712266fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.37e-051891226dc440015949a768188c67661b6be63b1ead1a0f0
ToppCellcellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.37e-051891226a3cd4c2da4feb9bdcd8957f3e344d095da1367b8
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

MOK CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.37e-05189122627329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellcellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.37e-05189122693b1026bb1ba759e5704561c9a5de14a30c08894
ToppCellEpithelial_cells-Ciliated_cells-A|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

MOK MNS1 CFAP45 CFAP74 CFAP53 CFAP157

1.41e-051901226549d813a8f23b175875e53347928941f143e236c
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MOK MNS1 TCHH CFAP45 CEP295 ANKRD36

1.41e-0519012260adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.41e-051901226a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCellcellseq2-Epithelial-Epithelial_Airway|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.41e-05190122617829f4de31b3d9e4d71ba4817d18842aa699773
ToppCellCiliated_cells-A|World / lung cells shred on cell class, cell subclass, sample id

MOK MNS1 CFAP45 CFAP74 CFAP53 CFAP157

1.41e-051901226cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MOK MNS1 TCHH CFAP45 CEP295 ANKRD36

1.41e-05190122605455775845f4ded5c27e7b83242078d23162aaf
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIP11 PRPF40A NCOR1 UBTF HPGD TBL1X

1.45e-05191122660c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIP11 PRPF40A NCOR1 UBTF HPGD TBL1X

1.45e-05191122609db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIP11 PRPF40A NCOR1 UBTF HPGD TBL1X

1.45e-051911226973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellControl-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

SYNE1 HKDC1 CRTAC1 MBIP PARD3 CADPS2

1.50e-0519212261bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCellCiliated-cil-3|World / Class top

MNS1 SYNE1 CFAP45 CFAP74 KIAA2012 CFAP53

1.50e-0519212264989ebb8812b8af1870599acd932849122c05a29
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SYNE1 CRTAC1 MBIP BMP1 PARD3 CADPS2

1.54e-051931226fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

MOK SYNE1 TSGA10 CFAP74 KIAA2012 CFAP53

1.54e-051931226ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SYNE1 CRTAC1 MBIP BMP1 PARD3 CADPS2

1.54e-051931226f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellASK440-Epithelial-Ciliated|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

MOK MNS1 TSGA10 CFAP45 CFAP53 CFAP157

1.54e-051931226a0baa8be6f590b2031fede22be588715ae458e93
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MOK MNS1 CFAP45 CFAP74 CFAP53 CFAP157

1.59e-0519412261ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.59e-05194122643be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MOK MNS1 CFAP45 KIAA2012 CFAP53 CFAP157

1.63e-0519512260e763f36786515698b593e5c93f6a56619c1242d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MOK MNS1 CFAP45 KIAA2012 CFAP53 CFAP157

1.63e-051951226581b04220587e1d5198b1abd6965965ace7803e7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MOK MNS1 CFAP45 KIAA2012 CFAP53 CFAP157

1.63e-05195122693b1559382a12cfb158aa5fac7386e38b4f87989
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MOK SYNE1 CFAP45 CFAP74 CFAP53 CFAP157

1.63e-0519512263486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MOK MNS1 CFAP45 CFAP74 CFAP53 CFAP157

1.63e-051951226e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellControl-Lymphoid-Proliferating_CD4_T_cells|Lymphoid / Condition, Lineage and Cell class

MNS1 CD109 ZWINT RACGAP1 GPSM2 NEXN

1.63e-051951226578bbb06a5476c08fc3b351cc580c551dfe53ae4
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MOK MNS1 CFAP45 CFAP74 CFAP53 CFAP157

1.68e-05196122627b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MOK MNS1 SYNE1 CFAP45 CFAP74 CFAP53

1.73e-0519712266865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 SPTBN4 NRG3 ATP2B2 MTUS2 CAP2

1.78e-051981226c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 SPTBN4 NRG3 ATP2B2 MTUS2 CAP2

1.78e-0519812264ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPTBN4 ANKRD36 NRG3 ATP2B2 MTUS2 CAP2

1.78e-0519812260ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCelldistal-Epithelial-Ciliated-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.83e-0519912262de1fe124737a6cca4b3805ab3056f9d9d7c16c7
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

MNS1 ANKRD26 TRIP11 PRPF40A RAD50 HPGD

1.83e-051991226fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.89e-05200122652aef65f01b06cd98056f17977efe525aee6eb6f
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.89e-05200122655c148238d5c80c1faa3428a917ae8075be2c145
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.89e-052001226926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.89e-05200122685c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCelldistal-3-Hematologic-Platelet/Megakaryocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.89e-052001226f5f5a8b0e4d802d95dc42646dd5e7d7daaad72b4
ToppCellNon-neuronal-Dividing-IPC|World / Primary Cells by Cluster

MNS1 TFDP2 ZWINT RACGAP1 GPSM2 PIF1

1.89e-052001226971533181daa1bfac1f1b8c507d2013f891f9078
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.89e-05200122612bc7d95c4166d12487081a76d210b7abe5991b0
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MNS1 CFAP45 CFAP74 KIAA2012 CFAP53 CFAP157

1.89e-05200122606ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MOK MNS1 CFAP45 KIAA2012 CFAP53 CFAP157

1.89e-0520012268441e289377215a6877640946fe3f6de1f456502
DrugBIPM

NSF CD109 BMP1 TNNT1

2.12e-06181204CID000117909
Drug1,1'-azobis(N,N-dimethylformamide

NSF ACO1 SPTAN1 IREB2 GSS PHB1 SPTBN4 SPTBN5

3.85e-061731208CID000004278
Drugplakin

SYNE1 SPTAN1 PPL SPTBN4 SPTBN5 PLEC

4.77e-06821206CID000018752
Drug3-methylitaconate

ACO1 SYNE1 IREB2

7.84e-0681203CID006438940
DrugAmbroxol hydrochloride [23828-92-4]; Down 200; 9.6uM; HL60; HG-U133A

SPTAN1 NUMA1 TFDP2 RAD50 NCOR1 SETD2 CFAP74 PARD3

8.30e-0619212081623_DN
DrugHarmalol hydrochloride dihydrate [6028-07-5]; Down 200; 14.6uM; PC3; HT_HG-U133A

SPTAN1 GAS8 TFDP2 RAD50 BMP1 FAM13A NF2 UBTF

8.95e-0619412085076_DN
DrugFenofibrate [49562-28-9]; Up 200; 11uM; HL60; HT_HG-U133A

NUMA1 ATP9B SPTBN5 BMP1 FAM13A ALDOB ATP2B2 ATP2B3

1.00e-0519712082401_UP
Drug1,4-dinitrobenzene

ACO1 IREB2 TNNT1

2.28e-05111203CID000007492
Drugp-nitrophenylhydroxylamine

ACO1 IREB2

2.75e-0521202CID005486551
Diseasevisceral heterotaxy (is_implicated_in)

MNS1 CFAP45 CFAP53

1.30e-05121173DOID:0050545 (is_implicated_in)
DiseaseNijmegen Breakage Syndrome-Like Disorder

MRE11 RAD50

1.56e-0521172C2751318
Diseasemalignant pleural mesothelioma (is_implicated_in)

SETD2 NF2

9.30e-0541172DOID:7474 (is_implicated_in)
Diseaseporphyria (implicated_via_orthology)

ACO1 IREB2

1.55e-0451172DOID:13268 (implicated_via_orthology)
DiseaseHailey-Hailey disease (implicated_via_orthology)

ATP2B2 ATP2B3

2.31e-0461172DOID:0050429 (implicated_via_orthology)
Diseaseinfluenza A (H1N1)

NUMA1 ADAM12 TFDP1 CFAP74

4.05e-04871174EFO_1001488
DiseaseNeurodevelopmental Disorders

TRIO CDC42BPB SETD2 ASXL3

5.22e-04931174C1535926
Diseasecerebral cavernous malformation (implicated_via_orthology)

CDC42BPG CDC42BPB

8.38e-04111172DOID:0060669 (implicated_via_orthology)
Diseasegastrointestinal stromal tumor (is_implicated_in)

SETD2 NF2

8.38e-04111172DOID:9253 (is_implicated_in)
Diseasehandedness

MNS1 FAM13A FLOT1 NPAS4

8.54e-041061174EFO_0009902
DiseaseMalignant mesothelioma

TFDP2 SETD2 NF2 CFAP45

9.48e-041091174C0345967
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GIGYF1 NCOR1 PARD3

9.80e-04491173DOID:0060037 (implicated_via_orthology)
DiseaseMetastatic melanoma

TRIO STK32A MAP3K10

1.30e-03541173C0278883
Diseasemalignant pleural mesothelioma (is_marker_for)

SETD2 NF2

1.38e-03141172DOID:7474 (is_marker_for)
DiseaseHereditary Breast and Ovarian Cancer Syndrome

MRE11 RAD50

1.38e-03141172C0677776
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

TRIO SETD2

2.04e-03171172DOID:0060307 (is_implicated_in)
Diseaseacute pancreatitis

MORC4 STK32A

2.29e-03181172EFO_1000652
Diseaseinterstitial lung disease

IREB2 FAM13A NRG3

2.42e-03671173EFO_0004244
Diseasebipolar I disorder

CACNB2 SYNE1 PLEC ATP2B2

2.44e-031411174EFO_0009963
Diseasefreckles

RAB11FIP2 PARD3

2.83e-03201172EFO_0003963
DiseaseMalignant neoplasm of breast

MRE11 SYNE1 SPTAN1 CD109 TNIP1 ADAM12 PHB1 BMP1 NCOR1 SETD2 NF2

3.66e-03107411711C0006142

Protein segments in the cluster

PeptideGeneStartEntry
KNQDLEFERNRERFE

ACO1

141

P21399
RDVIKEAKRQFARNQ

FAM227B

431

Q96M60
QRAAIQEREKQFRLQ

ARHGEF18

1016

Q6ZSZ5
ERQRNFEKQREERAA

ARHGEF18

1041

Q6ZSZ5
IQKRFREQERSREQG

ENKD1

111

Q9H0I2
QDQAQRDIIFELRRI

ELMO1

316

Q92556
EARVAQLREARAQQA

ATG16L2

136

Q8NAA4
QDSQKNVAVREIRRE

CRYBG3

516

Q68DQ2
RIKVENTEENRRQFR

ALDOB

46

P05062
VRRQLQREVDDALNK

ANKRD62

856

A6NC57
GRVVIFQREQENKSR

PPP2R2D

56

Q66LE6
VELVIVADNREFQRQ

ADAM12

216

O43184
REVAVRQLQQKRDDV

ANKRD36

1801

A6QL64
QQLRKREVRFERAEQ

DUS3L

216

Q96G46
LRFSLNQEEEKRRNA

ANKRD26

791

Q9UPS8
EDLRAFQVQQAVDLR

BMP1

61

P13497
TLLEEQVRKQENEFR

CFAP157

166

Q5JU67
RFQNRVREKQKLFQE

COX7A1

21

P24310
EFNRRIRNEKGEIEQ

ATP2B2

761

Q01814
FNRRIRNEKGEIEQE

ATP2B3

736

Q16720
DIKARAQQARAQREA

ASXL3

1056

Q9C0F0
RREAERQAQAQLEKA

CACNB2

96

Q08289
NRIDRQQFEETVRTL

GOLGA7

36

Q7Z5G4
RRFEEALRKNTEEQL

MTUS2

1211

Q5JR59
KQVAQQEAERARFVV

PHB1

186

P35232
RRKKPDRVFENQEVQ

RAD17

371

O75943
TDVRAQIRLQFRDVN

RAD50

76

Q92878
KNQEVEFGRNRERLQ

IREB2

216

P48200
FFRVSEEQQKQQRRE

CDC42BPG

1411

Q6DT37
FEELERQRQENRKKQ

NEXN

251

Q0ZGT2
EFRVKQLEDNIQRLE

PALM2

76

Q8IXS6
EREAQFVLRNEIQRD

NRG3

701

P56975
QLFKRRNVELINEEA

KPNA6

46

O60684
LRAAQEQRFQEEQLR

MAP3K10

406

Q02779
QRVLLQRDQNRDTDF

GPSM2

646

P81274
QEEEELFRRKHVRQQ

GIGYF1

721

O75420
LEEVRKQREEFQQQA

GOLGA1

486

Q92805
RRQQAELEAFENRLK

NFXL1

851

Q6ZNB6
EFRRFQRDKEVNSQL

ATP9B

201

O43861
LKQQRERQEAVEALF

DOP1B

1211

Q9Y3R5
EAQKLRDQRRFLEET

FAM184B

831

Q9ULE4
QQRREKTENEGRRKF

DDX55

501

Q8NHQ9
EEDQRFRVLLAVRQK

CCDC178

726

Q5BJE1
SEKIQEIQTFRERNR

CAP2

111

P40123
QDALRAKRNQEVADR

CFAP45

386

Q9UL16
RAQQVAVQEQEIARR

FLOT1

261

O75955
ENFINRNLEAKEERI

PPL

256

O60437
VFDREQNRRTLQIES

DCAF11

291

Q8TEB1
QRRQEFQIRALESQK

KIF21B

791

O75037
AAQERARQQQEEFRR

KIAA2012

1066

Q0VF49
NIRKLFADAEEEQRR

NSF

301

P46459
EQFVKDQERRQAARQ

TUBGCP6

711

Q96RT7
KQRFESIEQVNNLRE

MOK

36

Q9UQ07
FVFKVPEEERLQQRR

CDC42BPB

1556

Q9Y5S2
QLREKVQELQARRFS

DPY19L2

91

Q6NUT2
AEALKRRQQEVEERQ

DDX23

171

Q9BUQ8
FFRQNGRNVQKEDRT

FAM13A

976

O94988
RTRQQVFKNDARALE

LYRM7

16

Q5U5X0
QDLQEAREAERRAKQ

NF2

456

P35240
RQRKNRESFQIFLDE

PRPF40A

606

O75400
ERKRAAEQRQKAENF

ITPRIPL1

61

Q6GPH6
ARRDQINAEIRNLKE

NPAS4

11

Q8IUM7
QDFVAEKLDQQFRER

CFAP53

146

Q96M91
FIARARLEVENQAKR

COG5

231

Q9UP83
SVQVFQRELEVRQKR

FCSK

21

Q8N0W3
RRRSIQNQEAFDLDV

CD109

1271

Q6YHK3
ERIEALRKQFQTERE

CCDC150

826

Q8NCX0
FVRQNQDILREKVNE

CADPS2

1181

Q86UW7
EAERQRLEREKHFQQ

MAP7D1

686

Q3KQU3
RLEREKHFQQQEQER

MAP7D1

691

Q3KQU3
RRISAFIERKQAEIN

MBIP

161

Q9NS73
FIERKQAEINENNVR

MBIP

166

Q9NS73
DRAQKRLVNIAVDER

CRTAC1

86

Q9NQ79
QEKERNIFDQRAIEN

GSS

211

P48637
DIKQRRNQQFTRLAE

CEP295

51

Q9C0D2
VQQEEEKAEQRKRAR

SART3

591

Q15020
NLRNVVEAQFDSRVR

CPB1

96

P15086
RQRRDLIDKQQEAVA

CFAP74

106

Q9C0B2
EERQRFQEERQKLTA

NUMA1

1521

Q14980
RLRQEFQQAKQDEDV

PARD3

1156

Q8TEW0
FQQAKQDEDVEDRRR

PARD3

1161

Q8TEW0
ADQQQLRDTFRKVVD

HPGD

66

P15428
PRFKVNRRNLVEEVN

P2RX1

196

P51575
LIEERRQQFLADKQR

MNS1

411

Q8NEH6
FDKLEAVARAVRQQN

PIF1

316

Q9H611
KQEERAVRDRNLLQV

SPRING1

36

Q9H741
VVDELVRFRQKVRQF

CARS2

486

Q9HA77
AEQQRFRTEKERERQ

TNNT1

111

P13805
QLFEEASQVVERRQL

SYNE1

1851

Q8NF91
KREEEEKAQQVARRQ

HCLS1

251

P14317
EKAQQVARRQQERKA

HCLS1

256

P14317
KRRNEFDLDIVAVVN

HKDC1

641

Q2TB90
FPEIRKQREQQERFQ

NCOR1

346

O75376
RVLAERNLFQQKVEE

MORC4

781

Q8TE76
RNLFQQKVEELEQER

MORC4

786

Q8TE76
IFNREKVNRDFNKRQ

STK32A

361

Q8WU08
VRRFRETRQKNTNEE

MRE11

501

P49959
RNQVDVEIKRRQRAE

RACGAP1

76

Q9H0H5
DQKNIRRRVYDALNV

TFDP2

176

Q14188
AQDVEEQARRLLQRF

SPTBN5

2861

Q9NRC6
KQQCIERDEVRNVFR

STK32C

126

Q86UX6
QQERAREKRAQADAR

THAP7

276

Q9BT49
FENQRRNKREDRTFL

CILP

716

O75339
RIFEARTALQQREEK

ATP11B

646

Q9Y2G3
INANRRKLQRELDEA

MYH11

1896

P35749
DVVQTRQQAFREKLA

TBL1X

141

O60907
TRQREYQEKEIQRLN

TNIP1

406

Q15025
DQKNIRRRVYDALNV

TFDP1

161

Q14186
RKRTQLREAFEQLQA

ZWINT

126

O95229
KEFSQERQQEILRRA

ZDHHC20

96

Q5W0Z9
ERLERNFVDSRQLKV

RNF123

1056

Q5XPI4
EQRRQEENDKLRQEF

SPTAN1

2196

Q13813
KLDEEFQAQQRRVVI

TIGD4

271

Q8IY51
ERRQQVLDAAFQVEQ

SPTBN4

1611

Q9H254
ERRQQRKNREAFQTF

PRPF40B

486

Q6NWY9
VAINLNDIFEDKQRR

RAB11FIP2

101

Q7L804
RARAEEAEAQKRQAQ

PLEC

1616

Q15149
NRRFQRKQHADVEVI

SETD2

1541

Q9BYW2
RRKLFEQEVAQREAQ

SETD2

2121

Q9BYW2
KIDNFTRQNIAQREE

TSGA10

241

Q9BZW7
EVQRLRDKEFRSNQE

TRIP11

1566

Q15643
RRINRQLEALENDNF

ZNHIT1

26

O43257
QREKQEFERNLARFR

UBTF

166

P17480
FDSVQAKEQRRQQRL

UBR2

1181

Q8IWV8
KQQQRRERQDRVFQE

TCHH

226

Q07283
QQLSRQERDRKFREE

TCHH

1421

Q07283
QERDRKFREEEQQVR

TCHH

1426

Q07283
KFREEEQQVRRQERE

TCHH

1431

Q07283
EQQVRRQERERKFLE

TCHH

1436

Q07283
RQERERKFLEEEQQL

TCHH

1441

Q07283
RKFLEEEQQLRQERH

TCHH

1446

Q07283
QQLHRQERDRKFLEE

TCHH

1476

Q07283
QERDRKFLEEEQQLR

TCHH

1481

Q07283
KFLEEEQQLRRQERD

TCHH

1486

Q07283
FRLEEQKVRRQEQER

TCHH

1581

Q07283
RRQERERKFLQEEQQ

TCHH

1701

Q07283
QESDRKFREEEQLRQ

TCHH

1791

Q07283
QSQRERAEQNRIIFD

UCN

106

P55089
QLEDRIQDFVRRVEQ

TRIO

651

O75962
EFNQLRNILDRVEQR

TRIM6

186

Q9C030
LEQRFTKVQQERDEL

GAS8

331

O95995
RAVDQDKVLRFAQQI

MYORG

326

Q6NSJ0