Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3C RIMBP3 RIMBP3B

2.12e-0552593GO:0030156
GeneOntologyBiologicalProcessintracellular sphingolipid homeostasis

ABCA2 ORMDL1 ORMDL3 ORMDL2

3.57e-0762594GO:0090156
GeneOntologyBiologicalProcessnegative regulation of sphingolipid biosynthetic process

ABCA2 ORMDL1 ORMDL3 ORMDL2

8.25e-0772594GO:0090155
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

CCP110 ABCA2 TRAF3IP1 MAP1B NUMBL HJURP SAXO1 NCLN SACS EHMT2 METTL18 COBL SEMA4A PLXNB3 MPP7 FLNA TBC1D15 CARMIL1 VPS4B RICTOR C10orf90 ATP13A2 SHQ1 ORMDL1 ORMDL3 ORMDL2 NEURL1 SNX18 CNTNAP2 MED25 LIMCH1 RIMS1 CNOT1

1.62e-05118925933GO:0044087
GeneOntologyBiologicalProcessnegative regulation of ceramide biosynthetic process

ORMDL1 ORMDL3 ORMDL2

1.92e-0552593GO:1900060
GeneOntologyBiologicalProcessregulation of sphingolipid biosynthetic process

ABCA2 ORMDL1 ORMDL3 ORMDL2

3.93e-05162594GO:0090153
GeneOntologyCellularComponentcell-cell junction

MAGI1 XIRP1 SIPA1L3 MPDZ PTK7 FNDC1 FAT2 AJM1 NHS MPP7 MPP3 JCAD FLNA SYNM CNTNAP1 SHROOM2 CD2 CNTNAP2 PRKCG SCRIB CDH1

1.74e-0559126021GO:0005911
GeneOntologyCellularComponentadherens junction

MAGI1 XIRP1 FAT2 AJM1 MPP7 MPP3 JCAD SYNM SHROOM2 SCRIB CDH1

7.40e-0521226011GO:0005912
GeneOntologyCellularComponentanchoring junction

MAGI1 XIRP1 SIPA1L3 RPS8 MPDZ THSD1 PEAK3 PTK7 FNDC1 FAT2 AJM1 NHS MPP7 MPP3 JCAD FLNA FLNC SYNM CNTNAP1 SHROOM2 CD2 CNTNAP2 PRKCG SCRIB CDH1 EPB41L2 USP33

9.11e-0597626027GO:0070161
GeneOntologyCellularComponentserine palmitoyltransferase complex

ORMDL1 ORMDL3 ORMDL2

1.02e-0482603GO:0017059
GeneOntologyCellularComponentpalmitoyltransferase complex

ORMDL1 ORMDL3 ORMDL2

2.91e-04112603GO:0002178
DomainORMDL

ORMDL1 ORMDL3 ORMDL2

2.61e-0632583IPR007203
DomainORMDL

ORMDL1 ORMDL3 ORMDL2

2.61e-0632583PF04061
DomainIG_FLMN

POGLUT3 FLNA FLNC TRIM3

7.00e-06102584SM00557
DomainFilamin

POGLUT3 FLNA FLNC TRIM3

1.09e-05112584PF00630
DomainFILAMIN_REPEAT

POGLUT3 FLNA FLNC TRIM3

1.09e-05112584PS50194
DomainFilamin/ABP280_repeat-like

POGLUT3 FLNA FLNC TRIM3

1.09e-05112584IPR017868
DomainFilamin/ABP280_rpt

POGLUT3 FLNA FLNC TRIM3

1.09e-05112584IPR001298
DomainPDZ

MAGI1 SIPA1L3 MPDZ MPP7 MPP3 ARHGEF12 SHROOM2 RIMS1 SCRIB AHNAK2

2.69e-0514125810PF00595
DomainPDZ

MAGI1 SIPA1L3 MPDZ MPP7 MPP3 ARHGEF12 SHROOM2 RIMS1 SCRIB AHNAK2

4.08e-0514825810SM00228
Domain-

MAGI1 SIPA1L3 MPDZ MPP7 MPP3 ARHGEF12 SHROOM2 RIMS1 SCRIB AHNAK2

4.57e-05150258102.30.42.10
DomainPDZ

MAGI1 SIPA1L3 MPDZ MPP7 MPP3 ARHGEF12 SHROOM2 RIMS1 SCRIB AHNAK2

4.84e-0515125810PS50106
DomainPDZ

MAGI1 SIPA1L3 MPDZ MPP7 MPP3 ARHGEF12 SHROOM2 RIMS1 SCRIB AHNAK2

5.11e-0515225810IPR001478
DomainFA58C_3

F5 DDR1 CNTNAP1 CNTNAP2

1.77e-04212584PS50022
DomainFA58C

F5 DDR1 CNTNAP1 CNTNAP2

1.77e-04212584SM00231
DomainFA58C_1

F5 DDR1 CNTNAP1 CNTNAP2

1.77e-04212584PS01285
DomainFA58C_2

F5 DDR1 CNTNAP1 CNTNAP2

1.77e-04212584PS01286
DomainSH3_2

RIMBP3C VAV2 MPP7 MPP3 RIMBP3 SNX18 RIMBP3B

1.88e-04862587PF07653
DomainSH3_2

RIMBP3C VAV2 MPP7 MPP3 RIMBP3 SNX18 RIMBP3B

1.88e-04862587IPR011511
DomainFAM181

FAM181B FAM181A

1.90e-0422582IPR029359
DomainFAM181

FAM181B FAM181A

1.90e-0422582PF15238
DomainCH

LRCH1 VAV2 FLNA FLNC LRCH3 LIMCH1

2.74e-04652586SM00033
DomainF5_F8_type_C

F5 DDR1 CNTNAP1 CNTNAP2

3.04e-04242584PF00754
DomainFA58C

F5 DDR1 CNTNAP1 CNTNAP2

3.04e-04242584IPR000421
DomainIg-like_fold

POGLUT3 TRIO CD83 PTK7 FNDC1 PTPRZ1 CRLF3 RIMBP3C SEMA4A KIR2DS5 PLXNB1 PLXNB3 NDNF FLNA FLNC TRIM3 RIMBP3 CD2 IGHM TREM1 RIMBP3B FCAMR

3.38e-0470625822IPR013783
DomainCH

LRCH1 VAV2 FLNA FLNC LRCH3 LIMCH1

4.10e-04702586PF00307
Domain-

LRCH1 VAV2 FLNA FLNC LRCH3 LIMCH1

4.43e-047125861.10.418.10
DomainCH

LRCH1 VAV2 FLNA FLNC LRCH3 LIMCH1

5.15e-04732586PS50021
DomainCH-domain

LRCH1 VAV2 FLNA FLNC LRCH3 LIMCH1

5.95e-04752586IPR001715
DomainL27

MPDZ MPP7 MPP3

6.73e-04132583SM00569
DomainL27

MPDZ MPP7 MPP3

6.73e-04132583PS51022
DomainL27_dom

MPDZ MPP7 MPP3

6.73e-04132583IPR004172
DomainPlexin_repeat

SEMA4A PLXNB1 PLXNB3 ATRNL1

9.44e-04322584IPR002165
DomainPSI

SEMA4A PLXNB1 PLXNB3 ATRNL1

9.44e-04322584PF01437
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MAGI1 CCP110 HIVEP1 MAP1B TRIO NUMBL EXPH5 SEC24A SIPA1L3 HJURP MAP3K20 MPDZ IRS1 SYNJ2 COBL NHS KIF2A HECTD1 JCAD CARMIL1 APBB1 RICTOR ALS2 CBX4 CDC14A DENND4C E2F8 C2CD3 NEURL1 PRKCG LIMCH1 SCRIB AQR EPB41L2 AHNAK2

8.38e-168612653536931259
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MAP1B TRIO NUMBL SIPA1L3 RPS8 SACS WASHC5 PTPRZ1 AJM1 KIF2A METAP2 VARS1 WNK2 GPI FLNA FLNC SFPQ CARMIL1 CNTNAP1 ARHGEF12 KIAA1549 UPF1 IDH2 SHROOM2 TRIM3 LRCH3 GUCY1A2 TKT IGHM TMPO PRKCG LIMCH1 RIMS1 SCRIB CNOT1 EPB41L2

3.59e-1014312653637142655
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MAGI1 NCOA3 TRAF3IP1 TRIO NUMBL SIPA1L3 MPDZ EHMT2 KIF2A MGA KCNT1 WNK2 SFPQ CNTNAP1 NSD1 ARHGEF12 UPF1 TRIM3 NCOR2 PRKCG LIMCH1 RIMS1 SCRIB CABIN1 CNOT1 EPB41L2 PHACTR1

7.35e-099632652728671696
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ABCA2 KMT2B TRIO SIPA1L3 SREBF1 IRS1 NCLN TRRAP ELAC2 TMCC2 MCM3AP COBL HECTD1 WNK2 MPP3 FLNA FLNC BICRA NSD1 ATP13A2 CCDC142 NCOR2 C2CD3 CTDP1 HMGXB3 DEPDC5 STK40 CABIN1 AHNAK2

8.52e-0911052652935748872
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

HJURP RIPPLY3 ITGA9 ZFYVE1 SIAE KIF2A MTO1 MGA PLXNB1 FLNA SFPQ NSD1 RICTOR ALS2 SHROOM2 ZNF496 E2F8 CCND2 NPHP3 PAXBP1 TBC1D31 SLC20A1 ATRNL1 GRAMD2B HMGXB3 CDH1 CNOT1 PHACTR1

2.19e-0810842652811544199
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

MAGI1 MAP1B NUMBL SEC24A RPS8 MPDZ THSD1 ARHGAP29 MPP7 TBCE TBC1D15 CARMIL1 ATG2B ARHGEF12 RICTOR UPF1 DENND4C TMPO LRP6 SCRIB CNOT1 EPB41L2

3.27e-087082652239231216
Pubmed

DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169.

SIPA1L3 IRS1 LRCH1 JCAD FLNC SFPQ TROAP LRCH3 SNX18 CNOT1

3.63e-081222651030773093
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

MAP1B TRIO AASDHPPT NCLN PTK7 CACNG3 WASHC5 AJM1 TMCC2 KIF2A VARS1 WNK2 JCAD FLNA SFPQ U2SURP CNTNAP1 ATG2B APBB1 RICTOR IDH2 SHROOM2 CNTNAP2 PRKCG RIMS1 CNOT1 EPB41L2 PHACTR1

6.16e-0811392652836417873
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

MAGI1 CCP110 SIPA1L3 MAP3K20 MPDZ LRCH1 CRLF3 KIF2A HECTD1 MPP7 JCAD KIAA1549 RICTOR DENND4C LRCH3 SNX18 CNOT1

7.24e-084462651724255178
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

CCP110 TRIO SIPA1L3 MPDZ ARHGAP29 COBL NHS HECTD1 ATG2B ARHGEF12 DENND4C SCRIB

8.32e-082092651236779422
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

MAP1B WASHC5 MGA VARS1 FLNA FLNC ATG2B RICTOR UPF1 TMPO SCRIB EPB41L2

1.13e-072152651235973513
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

METTL3 KMT2B GALNT3 NUMBL SIPA1L3 MAP3K20 MPDZ TMEM205 TRRAP NKRF MAN1A2 EHMT2 METTL18 KIF2A VARS1 MPP7 RCE1 REXO4 PARP2 NSD1 ARHGEF12 RICTOR CBX4 LRCH3 ORMDL1 PAXBP1 BAZ2A SLC25A10 MED25 LIMCH1 AQR EPB41L2

1.62e-0714972653231527615
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

SIPA1L3 RPS8 KRBA1 MCM3AP ARHGAP29 MGA SYNM U2SURP NCOR2 C2CD3 ZNF69

1.93e-071842651132908313
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

KMT2B EHMT2 SYNJ2 MYO18B WNK2 FLNA FLNC AFF2 BICRA CNTNAP1 SHROOM2 BAZ2A TMPO RIMS1

2.82e-073292651417474147
Pubmed

ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins.

ORMDL1 ORMDL3 ORMDL2

4.37e-073265312093374
Pubmed

Mammalian ORMDL proteins mediate the feedback response in ceramide biosynthesis.

ORMDL1 ORMDL3 ORMDL2

4.37e-073265323066021
Pubmed

A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib.

SEMA4A PLXNB1 SCRIB

4.37e-073265328007914
Pubmed

Simultaneous reduction of all ORMDL proteins decreases the threshold of mast cell activation.

ORMDL1 ORMDL3 ORMDL2

4.37e-073265337316542
Pubmed

Expression of the ORMDLS, modulators of serine palmitoyltransferase, is regulated by sphingolipids in mammalian cells.

ORMDL1 ORMDL3 ORMDL2

4.37e-073265325395622
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NCOA3 HIVEP1 KMT2B EHMT2 TAF1 MGA S100PBP FLNA TBC1D15 VPS4B ATG2B DENND4C NCOR2 TLE1 CNOT1

9.17e-074182651534709266
Pubmed

A human MAP kinase interactome.

MAGI1 HIVEP1 EXPH5 SYNJ2 MCM3AP COBL TAF1 MGA WNK2 FLNA FLNC SFPQ BICRA CBLB IRAG2 EPB41L2

1.22e-064862651620936779
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

MAGI1 WWC3 SIPA1L3 RPS8 IRS1 ELAC2 NKRF AXIN2 NHS KIF2A MGA HECTD1 VARS1 GPI ANKRD35 FLNA TCF7 SFPQ VPS4B U2SURP UPF1 NCOR2 PAXBP1 TMPO LIMCH1 CDH1 AQR

1.26e-0612472652727684187
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KMT2B MAP1B MPDZ TRRAP NKRF TAF1 MGA FLNA TBC1D15 ATG2B APBB1 NSD1 UPF1 BAZ2A TMPO SCRIB CNOT1

1.31e-065492651738280479
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

CCDC125 TMEM126B SREBF1 TRRAP EHMT2 MCM3AP NHS THAP3 MTO1 MGA HECTD1 TBCE ASNSD1 GPI FLNA BICRA RICTOR C10orf90 SPACA9 UPF1 SNX14 TKT SLC20A1 TLE1 SLC25A10 DEPDC5 CNOT1 PADI3

1.31e-0613272652832694731
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

POGLUT3 NUMBL TMEM126B RPS8 MRPL43 MPDZ NCLN ELAC2 CEMIP2 PTK7 NCBP3 SACS EHMT2 MPP7 TBC1D15 SYNM APBB1 KIAA1549 RICTOR UPF1 PAXBP1 TBC1D31 BAZ2A SLC20A1 TRABD TMPO SCRIB AQR EPB41L2 USP33

1.34e-0614872653033957083
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

KMT2B SYNJ2 SYNM U2SURP ARHGEF12 BAZ2A RIMS1 CABIN1

1.40e-0610426589205841
Pubmed

Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b.

SEC24A PTK7 SCRIB CDH1

1.55e-0612265420215345
Pubmed

DNA sequence polymorphism in an androgen-regulated gene is associated with alteration in the encoded RNAs.

CYP2A6 CYP2A13 GPI

1.74e-06426536188152
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3C RIMBP3 RIMBP3B

1.74e-064265319091768
Pubmed

The Ormdl genes regulate the sphingolipid synthesis pathway to ensure proper myelination and neurologic function in mice.

ORMDL1 ORMDL3 ORMDL2

1.74e-064265331880535
Pubmed

The genes for mouse salivary androgen-binding protein (ABP) subunits alpha and gamma are located on chromosome 7.

CYP2A6 CYP2A13 GPI

1.74e-06426533569880
Pubmed

Orm family proteins mediate sphingolipid homeostasis.

ORMDL1 ORMDL3 ORMDL2

1.74e-064265320182505
Pubmed

A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP.

CYP2A6 CYP2A13 CYP2D6

1.74e-06426537565685
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

MAGI1 NUMBL SIPA1L3 CEMIP2 SYNJ2 ARHGAP29 NHS MPP7 JCAD FLNA CARMIL1 ARHGEF12 DENND4C TMPO LIMCH1 SCRIB CDH1

1.93e-065652651725468996
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NCOA3 HIVEP1 KMT2B ESRRA PEPD TRRAP UNG FLNA CARMIL1 RICTOR NCOR2 PAXBP1 BAZ2A TKT CTDP1 TMPO LIMCH1 RIMS1 SCRIB EPB41L2

2.45e-067742652015302935
Pubmed

Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF.

PLXNB1 PLXNB3 ARHGEF12

4.32e-065265312183458
Pubmed

Lyb-8.2: A new B cell antigen defined and characterized with a monoclonal antibody.

CYP2A6 CYP2A13 GPI

4.32e-06526536984010
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3C RIMBP3 RIMBP3B

4.32e-065265317855024
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

MAP1B RPS8 NCLN TRRAP F5 NKRF NCBP3 SACS KIF2A MGA VARS1 GPI FLNA FLNC TBC1D15 SFPQ U2SURP SLC20A1 TMPO SCRIB CNOT1 AQR EPB41L2

4.44e-0610242652324711643
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

TRIO LRCH1 CEMIP2 PTK7 COBL NHS MPP7 CARMIL1 RICTOR ERICH5 CBLB LRCH3 SCRIB EPB41L2

5.10e-064212651436976175
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MAP1B RPS8 MAP3K20 TRRAP ELAC2 NKRF WASHC5 MCM3AP KIF2A MGA METAP2 VARS1 GPI FLNA FLNC REXO4 SFPQ U2SURP RICTOR UPF1 NCOR2 BAZ2A TKT SCRIB AQR EPB41L2 AHNAK2

5.71e-0613532652729467282
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

SREBF1 AASDHPPT TRRAP EHMT2 COBL MGA VAV2 MAP3K19 ASNSD1 JCAD FLNA FAT4 TBC1D15 SFPQ UPF1 NCOR2 TRABD IRAG2 LIMCH1

6.29e-067542651935906200
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

EXPH5 SEC24A NHS SYNM APBB1 KIAA1549 TBC1D31 MEIOC SCRIB CNOT1 AHNAK2

6.36e-062632651134702444
Pubmed

The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle.

PHLDA2 SYNJ2 GPI KIAA1549 TKT SLC25A10

6.56e-0660265621555518
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

TRIO NUMBL SEC24A SIPA1L3 CEMIP2 WASHC5 PTPRZ1 CRLF3 NHS UNG MPP7 JCAD KIAA1549 RICTOR PTPN18 CDC14A NCOR2 C2CD3 TBC1D31 TMPO LRP6 SCRIB CNOT1

6.56e-0610492652327880917
Pubmed

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.

CYP2A6 FREM2 MCM3AP KIF2A FAM181B TBC1D15 CBX4 CBLB SEC31B SHQ1 BAZ2A TKT SLC20A1 ZNF804B

6.66e-064312651433660365
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CCP110 EXPH5 RC3H1 SIPA1L3 KRBA1 AHRR FAT2 SACS TMCC2 MGA HECTD1 SYNM RICTOR NPHP3 ATRNL1

6.83e-064932651515368895
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

ABCA2 SYNJ2 MCM3AP HECTD1 PLXNB3 U2SURP KIAA1549 CNTNAP2

7.45e-06130265812421765
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

EXPH5 NCLN TRRAP NCBP3 KRBA1 COBL UNG KIF2A CARMIL1 U2SURP SNX14 SLC25A10 TMPO LIMCH1 CNOT1

7.52e-064972651536774506
Pubmed

ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis.

ORMDL1 ORMDL3 ORMDL2

8.60e-066265325691431
Pubmed

Genetic regulation of coumarin hydroxylase activity in mice. Evidence for single locus control on chromosome.

CYP2A6 CYP2A13 GPI

8.60e-0662653447675
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

MAGI1 NUMBL EXPH5 CEMIP2 PTK7 COBL PLXNB1 MPP7 CARMIL1 APBB1 KIAA1549 RICTOR ATP10D GRAMD2B SCRIB EPB41L2

9.04e-065692651630639242
Pubmed

Single nucleotide polymorphisms in the Wnt and BMP pathways and colorectal cancer risk in a Spanish cohort.

AXIN2 TCF7 TLE1 CDH1

9.27e-0618265420844743
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

MAGI1 RC3H1 SIPA1L3 MPDZ NCBP3 COBL JCAD FLNA SFPQ UPF1 SCRIB

9.36e-062742651134244482
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

TRIO EML6 SACS SEMA4A FLNA NSD1 SPACA9 KCTD20 HMGXB3 SCRIB CNOT1 AHNAK2

1.06e-053322651237433992
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

CCP110 METTL3 MAP1B F5 ELAC2 EHMT2 UNG PARP2 ATG2B CBX4 DENND4C C2CD3 TBC1D31 MED25 SCRIB CABIN1 CNOT1

1.10e-056452651725281560
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

MAP1B SREBF1 MPDZ NCLN NKRF CEMIP2 PTK7 FREM2 WASHC5 KIF2A PLXNB1 RICTOR SLC25A10 SCRIB RUBCN AQR USP33

1.21e-056502651738777146
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

METTL3 EXPH5 SIPA1L3 RPS8 MAP3K20 LRCH1 F5 NKRF KIF2A METAP2 FLNA REXO4 SFPQ SYNM DDX60 PARP2 UPF1 LRCH3 TKT KCTD20 TMPO SCRIB CDH1 AQR EPB41L2

1.36e-0512572652536526897
Pubmed

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses.

CYP2A6 CYP2A13 CYP2D6

1.50e-05726539630227
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

MAN2C1 MAP1B SEC24A TRRAP HECTD1 VARS1 GPI FLNA FLNC SFPQ UPF1 TKT

1.51e-053442651230333137
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ABCA2 ZFYVE1 LRCH1 CEMIP2 SYNJ2 WASHC5 KCNT1 WNK2 PLXNB1 CERK KIAA1549 CNTNAP2 HMGXB3 DEPDC5 CNOT1

1.57e-055292651514621295
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ABCA2 GALNT3 MAP1B SREBF1 EXTL2 NCLN ELAC2 CEMIP2 PTK7 SIAE MAN1A2 KIF2A HECTD1 PLXNB1 RCE1 FAT4 CNTNAP1 KIAA1549 H6PD SNX14 TMPO LRP6 CERCAM SCRIB

1.89e-0512012652435696571
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

TRAF1 HIVEP1 KMT2B NUMBL PEPD SREBF1 ARID5A SACS TAF1 WNK2 FAT4 APBB1 IGHM TMPO PRKCG EPB41L2

2.03e-056082651616713569
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

NCOA3 RC3H1 UNG SFPQ TROAP BICRA CBX4 NCOR2

2.33e-05152265838360978
Pubmed

cDNAs with long CAG trinucleotide repeats from human brain.

MAGI1 NCOA3 NUMBL NCOR2

2.60e-052326549225980
Pubmed

HiPLA: High-throughput imaging proximity ligation assay.

EHMT2 CBX4 SIRT6 NCOR2 TMPO

2.63e-0546265530419336
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

TRIO HECTD1 FLNA DDX60 CNTNAP1 RICTOR CNTNAP2 TMPO CNOT1

2.71e-05202265933005030
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

MAP1B NUMBL RPS8 LRCH1 TRRAP NKRF SACS KIF2A VARS1 PLXNB1 FLNC REXO4 SFPQ U2SURP CBX4 UPF1 IDH2 PAXBP1 SLC25A10 TMPO CNOT1 AQR

3.29e-0510822652238697112
Pubmed

Hmga2 is required for canonical WNT signaling during lung development.

AXIN2 CCND2 LRP6 CDH1

3.67e-0525265424661562
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

CCP110 NCOA3 METTL3 MAP3K20 PHLDA2 EHMT2 NHS FLNA TBC1D15 TROAP DENND4C CTDP1 SCRIB EPB41L2

3.68e-055032651416964243
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

MAP1B NUMBL RPS8 PEPD AASDHPPT NKRF GPI FLNA SFPQ CARMIL1 U2SURP ATG2B APBB1 UPF1 BAZ2A TKT TMPO SCRIB EPB41L2 AHNAK2

3.71e-059342652033916271
Pubmed

Insights into the ubiquitin-proteasome system of human embryonic stem cells.

TAF1 HECTD1 U2SURP UPF1 PAXBP1 TMPO ATP1A4 CDH1 AQR EPB41L2

4.57e-052692651029511261
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MAP1B RC3H1 ESRRA ZFYVE1 SYNJ2 MGA METAP2 VARS1 FLNA FLNC REXO4 DDX60 UPF1 TKT SNX18 CNOT1 AHNAK2

4.70e-057242651736232890
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MAP1B TRRAP NKRF MCM3AP HECTD1 FLNA FLNC REXO4 SFPQ U2SURP NSD1 UPF1 BAZ2A CNOT1 AQR EPB41L2

4.77e-056532651622586326
Pubmed

Interaction of the human somatostatin receptor 3 with the multiple PDZ domain protein MUPP1 enables somatostatin to control permeability of epithelial tight junctions.

MAGI1 MPDZ SCRIB

5.05e-0510265319071123
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

POGLUT3 SEC24A RPS8 IRS1 NCLN ZFYVE1 PTK7 MAN1A2 AJM1 VARS1 ANKRD35 FLNA FLNC SFPQ U2SURP CNTNAP1 CBX4 IDH2 H6PD NCOR2 ORMDL3 TKT TLE1 SLC25A10 CERCAM EPB41L2

5.31e-0514512652630550785
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

CCP110 NCOA3 NUMBL SEC24A RPS8 MAP3K20 ZFYVE1 LRCH1 WASHC5 MCM3AP ARHGAP29 METAP2 TBC1D15 RICTOR UPF1 DENND4C SHQ1 SNX18 KCTD20 LIMCH1 CNOT1

5.35e-0510382652126673895
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ABCA2 TRAF3IP1 TRIO SIPA1L3 RIPPLY3 MAN1A2 SACS EHMT2 TAF1 HECTD1 METAP2 VARS1 PLXNB3 JCAD SYNM CNTNAP1 APBB1 SEC31B SHROOM2 ATRNL1 CERCAM SCRIB CABIN1 USP33

5.51e-0512852652435914814
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

RPS8 HJURP SREBF1 IRS1 NCLN LRCH1 TMEM205 CEMIP2 PTK7 MAN1A2 WASHC5 MGA GPI FLNA FLNC TBC1D15 SFPQ CNTNAP1 CBX4 NCOR2 TMPO CNOT1 AQR

5.57e-0512032652329180619
Pubmed

Semaphorin4A promotes lung cancer by activation of NF-κB pathway mediated by PlexinB1.

SEMA4A PLXNB1

5.78e-052265237901456
Pubmed

Suppressed hepatocyte proliferation via a ROS-HNE-P21 pathway is associated with nicotine- and cotinine-enhanced alcoholic fatty liver in mice.

CYP2A6 CYP2A13

5.78e-052265230876690
Pubmed

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors.

IRS1 DDR1

5.78e-052265217721511
Pubmed

Loss of FilaminC (FLNc) results in severe defects in myogenesis and myotube structure.

TRIO FLNC

5.78e-052265216914736
Pubmed

Molecular characterization of the murine Coh locus: an amino acid difference at position 117 confers high and low coumarin 7-hydroxylase activity in P450coh.

CYP2A6 CYP2A13

5.78e-05226521302041
Pubmed

Nizp1, a novel multitype zinc finger protein that interacts with the NSD1 histone lysine methyltransferase through a unique C2HR motif.

NSD1 ZNF496

5.78e-052265215169884
Pubmed

Scribble and E-cadherin cooperate to control symmetric daughter cell positioning by multiple mechanisms.

SCRIB CDH1

5.78e-052265236661138
Pubmed

Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells.

NCOA3 VAV2

5.78e-052265228356423
Pubmed

Effect of pyrazole, cobalt and phenobarbital on mouse liver cytochrome P-450 2a-4/5 (Cyp2a-4/5) expression.

CYP2A6 CYP2A13

5.78e-05226521520280
Pubmed

Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a CYP2A13-humanized mouse model.

CYP2A6 CYP2A13

5.78e-052265223917075
Pubmed

Obligatory roles of filamin A in E-cadherin-mediated cell-cell adhesion in epidermal keratinocytes.

FLNA CDH1

5.78e-052265224120284
Pubmed

Circadian Regulation of Hepatic Cytochrome P450 2a5 by Peroxisome Proliferator-Activated Receptor γ.

CYP2A6 CYP2A13

5.78e-052265230154104
Pubmed

ORMDL proteins regulate ceramide levels during sterile inflammation.

ORMDL1 ORMDL3

5.78e-052265227313060
Pubmed

Stimulation of Slack K(+) Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex.

KCNT1 PHACTR1

5.78e-052265227545877
Pubmed

Mechanism-based inhibition of cytochrome P450 (CYP)2A6 by chalepensin in recombinant systems, in human liver microsomes and in mice in vivo.

CYP2A6 CYP2A13

5.78e-052265221418183
Pubmed

Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone binding and access channel in human cytochrome P450 2A6 and 2A13 enzymes.

CYP2A13 CYP2D6

5.78e-052265222700965
Pubmed

The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin.

SCRIB CDH1

5.78e-052265216344308
Pubmed

METTL3 Promotes Osteosarcoma Metastasis via an m6A-dependent Epigenetic Activity of CBX4.

METTL3 CBX4

5.78e-052265238538251
Pubmed

Filamin isogene expression during mouse myogenesis.

FLNA FLNC

5.78e-052265210679933
Pubmed

NSD1 PHD domains bind methylated H3K4 and H3K9 using interactions disrupted by point mutations in human sotos syndrome.

NSD1 ZNF496

5.78e-052265221972110
Pubmed

A novel structural unit in the N-terminal region of filamins.

FLNA FLNC

5.78e-052265224469451
InteractionYWHAH interactions

CCDC125 MAGI1 CCP110 NCOA3 ABCA2 HIVEP1 TRIO NUMBL EXPH5 SEC24A SIPA1L3 HJURP MAP3K20 MPDZ IRS1 SYNJ2 SRSF8 COBL NHS KIF2A HECTD1 WNK2 JCAD CARMIL1 APBB1 RICTOR ALS2 CBX4 CDC14A DENND4C E2F8 C2CD3 LIMCH1 RIMS1 SCRIB RUBCN AQR EPB41L2 AHNAK2

8.68e-09110225939int:YWHAH
InteractionYWHAG interactions

MAGI1 CCP110 HIVEP1 NUMBL EXPH5 SEC24A RC3H1 SIPA1L3 HJURP MAP3K20 MPDZ IRS1 TRRAP SYNJ2 SRSF8 OSBPL7 ARHGAP29 COBL NHS KIF2A HECTD1 JCAD FLNA CARMIL1 APBB1 RICTOR ALS2 CBX4 SHROOM2 CDC14A DENND4C E2F8 LRCH3 C2CD3 PRKCG SCRIB RUBCN AQR EPB41L2 AHNAK2

8.21e-08124825940int:YWHAG
InteractionSFN interactions

CCDC125 MAGI1 CCP110 MAP1B EXPH5 SIPA1L3 RPS8 MAP3K20 IRS1 SYNJ2 SRSF8 COBL NHS KIF2A HECTD1 JCAD SFPQ CARMIL1 RICTOR CBX4 TEX14 DENND4C TKT SCRIB CDH1 EPB41L2 AHNAK2

3.17e-0769225927int:SFN
InteractionYWHAE interactions

CCDC125 HIVEP1 MAP1B NUMBL EXPH5 SEC24A RC3H1 SIPA1L3 RPS8 HJURP MAP3K20 IRS1 LRCH1 SYNJ2 NHS MGA HECTD1 METAP2 WNK2 JCAD FLNA SFPQ RICTOR ALS2 CBX4 SHROOM2 CDC14A DENND4C E2F8 LRCH3 NCOR2 IRAG2 TMPO PRKCG DEPDC5 CDH1 RUBCN EPB41L2

7.59e-07125625938int:YWHAE
InteractionVASP interactions

MAGI1 CCP110 XIRP1 NUMBL SEC24A SIPA1L3 MRPL43 MPDZ SYNJ2 NHS APBB1 ARHGEF12 RICTOR LIMCH1 CDH1

6.68e-0629425915int:VASP
InteractionGSK3B interactions

CCP110 NCOA3 MAP1B TRIO SIPA1L3 SREBF1 MPDZ IRS1 AXIN2 KRBA1 ARHGAP29 COBL NHS HECTD1 GPI FLNA SFPQ ATG2B ARHGEF12 RICTOR C10orf90 DENND4C TLE1 IGHM TMPO LRP6 SCRIB CDH1

7.69e-0686825928int:GSK3B
InteractionGSK3A interactions

CCP110 TRIO SIPA1L3 RPS8 MPDZ AXIN2 KRBA1 ARHGAP29 COBL NHS HECTD1 U2SURP ATG2B ARHGEF12 RICTOR DENND4C LRP6 PRKCG SCRIB

9.76e-0646425919int:GSK3A
InteractionLIN7A interactions

MPDZ MPP7 MPP3 GUCY1A2 SLC20A1 CNTNAP2 EPB41L2

1.03e-05592597int:LIN7A
InteractionITGB3 interactions

MAN2C1 MAP1B SEC24A TRRAP PTPRZ1 HECTD1 VARS1 FLNA FLNC SFPQ UPF1

1.30e-0517025911int:ITGB3
InteractionKCNA3 interactions

MAGI1 MAP1B NUMBL EXPH5 SEC24A RPS8 MPDZ THSD1 KCNC4 ARHGAP29 COBL MPP7 TBCE TBC1D15 AFF2 CARMIL1 ATG2B ARHGEF12 RICTOR UPF1 DENND4C TMPO LRP6 RIMS1 SCRIB CNOT1 EPB41L2

2.28e-0587125927int:KCNA3
CytobandEnsembl 112 genes in cytogenetic band chr9q34

ABCA2 AJM1 KCNT1 VAV2 REXO4 SPACA9 CRAT CERCAM ENTPD8

1.35e-043252679chr9q34
Cytoband1p21

EXTL2 KCNC4 CDC14A

3.60e-042426731p21
CytobandEnsembl 112 genes in cytogenetic band chr11q22

POGLUT3 EXPH5 AASDHPPT MMP10 GUCY1A2

4.20e-041072675chr11q22
GeneFamilyPDZ domain containing

MAGI1 SIPA1L3 MPDZ MPP7 MPP3 ARHGEF12 SHROOM2 RIMS1 SCRIB AHNAK2

1.50e-06152167101220
GeneFamilyAtaxins|Trinucleotide repeat containing

MAGI1 NCOA3 NUMBL NCOR2

7.63e-05251674775
GeneFamilyPeptidyl arginine deiminases

PADI4 PADI3

8.33e-0451672677
CoexpressionGSE37301_CD4_TCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN

TRAF1 HIVEP1 CD83 ARID5A SEMA4A VARS1 TCF7 CBX4 CBLB CDC14A SLC20A1

2.15e-0618026211M8898
CoexpressionGEORGES_TARGETS_OF_MIR192_AND_MIR215

NCOA3 POGLUT3 WWC3 HJURP MRPL43 AASDHPPT EXTL2 CD83 TMC3 NKRF CEMIP2 CRLF3 ARHGAP29 UNG GNRH1 TCF7 TROAP ERICH5 CDC14A E2F8 NPHP3 TBC1D31 ATRNL1 TMPO LIMCH1

3.87e-0689226225M18120
CoexpressionGSE360_DC_VS_MAC_L_MAJOR_UP

EXPH5 PHLDA2 VARS1 FLNA UPF1 PTPN18 CRAT TRIM3 NCOR2 TLE1 KCTD20

5.93e-0620026211M5181
CoexpressionHALLMARK_APICAL_JUNCTION

TRAF1 MAP3K20 IRS1 ITGA9 VAV2 FLNC SHROOM2 CRAT CERCAM CDH1 EPB41L2

5.93e-0620026211M5915
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA9 SCNN1G COBL MPP7 MPP3 NDNF DDR1 CARMIL1 PAXBP1 LIMCH1 CDH1

1.59e-08186264113aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

EXPH5 SCNN1G COBL PLXNB1 MPP3 NDNF IRAG2 CERCAM LIMCH1 CDH1 FCAMR

3.20e-0819926411d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA9 SCNN1G COBL MPP7 MPP3 NDNF CARMIL1 LIMCH1 CDH1 PHACTR1

1.11e-07177264109af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KMT2B MGA TCF7 PGGHG TROAP RICTOR CBX4 MEIOC LIMCH1 CNOT1

1.17e-0717826410c87945146b2734141f07b39d268e0d8086ee0364
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA9 SCNN1G COBL MPP7 MPP3 NDNF DDR1 PAXBP1 LIMCH1 CDH1

1.37e-0718126410b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

MAGI1 CCP110 SIPA1L3 SCNN1G COBL PGGHG CARMIL1 LIMCH1 CDH1 PHACTR1

1.68e-071852641032b4e68e551d435a732f253f6ad83408c759a642
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SIPA1L3 ITGA9 COBL MPP7 MPP3 NDNF DDR1 PAXBP1 LIMCH1 CDH1

1.85e-071872641058d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

NCOA3 HIVEP1 TRIO SIPA1L3 CD83 VAV2 CARMIL1 IGHM RUBCN PHACTR1

2.15e-07190264101e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP1B ITGA9 JCAD FLNA SFPQ ARHGEF12 CCND2 CD2 IGHM EPB41L2

2.15e-0719026410d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellClub_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CYP2A6 FAT2 PTPRZ1 SCNN1G WNK2 DDR1 MUC16 GRAMD2B RIMS1 CDH1

2.48e-07193264106582c0367052b9d10fb629c383ee0c55872afd2d
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

EXPH5 SCNN1G COBL PLXNB1 MPP3 NDNF CARMIL1 CERCAM LIMCH1 CDH1

3.14e-071982641085f424cd9bb3117c9e322031024aabb87696ce47
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI1 EXPH5 FREM2 COBL FHIT MPP7 LRP6 LIMCH1 CDH1 PHACTR1

3.29e-07199264105f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI1 EXPH5 SIPA1L3 FREM2 COBL FHIT MPP7 LIMCH1 CDH1 PHACTR1

3.29e-07199264105cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MAP1B MAP3K20 IRS1 FNDC1 FLNA AFF2 GUCY1A2 PRELP ATRNL1 ATP1A4

3.45e-0720026410f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

EXPH5 ITGA9 SCNN1G COBL PLXNB1 MPP3 NDNF IRAG2 CERCAM CDH1

3.45e-0720026410ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

EXPH5 SCNN1G COBL PLXNB1 MPP3 NDNF IRAG2 CERCAM LIMCH1 CDH1

3.45e-07200264108683445ad5b70748c4a1f12eb77d47623085147e
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MAP1B MAP3K20 IRS1 ITGA9 FNDC1 NDNF FLNA PRELP ATRNL1 ATP1A4

3.45e-07200264108988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EXPH5 FAT2 PTPRZ1 HECTD1 PLXNB1 DDR1 ARHGEF12 MUC16 CDH1 AHNAK2

3.45e-0720026410ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HJURP FNDC1 SACS UNG JCAD FLNA TROAP GUCY1A2 PRELP

5.28e-071612649a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HJURP FNDC1 SACS UNG JCAD FLNA TROAP GUCY1A2 PRELP

5.28e-07161264908920a716f6ec62538e361211455a30ad726d7be
ToppCellControl-B_naive-11|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CEMIP2 FAM181B IGHM CNTNAP2 TMPO LIMCH1 EPB41L2 PHACTR1

8.74e-071262648319a4c325e0e5c14bb49a143b8924c554f834cc0
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CYP2A6 CYP2A13 FAT2 PTPRZ1 SCNN1G MMP10 WNK2 MUC16 RIMS1

9.64e-071732649d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCellP03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MAGI1 SCNN1G NDNF DDR1 APBB1 TRIM3 LIMCH1 CDH1 PHACTR1

1.11e-061762649f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B SRSF8 FLNA FLNC SYNM GUCY1A2 PRELP MYH15 AHNAK2

1.17e-06177264988403b055eb9fdf96e4695fb6e0d78179e30a1e3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B SRSF8 FLNA FLNC SYNM GUCY1A2 PRELP MYH15 AHNAK2

1.17e-0617726498903aeaab61abd81a148ea623038c5114b8a183b
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA9 SCNN1G COBL MPP3 NDNF DDR1 PAXBP1 LIMCH1 CDH1

1.61e-06184264942ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

FNDC1 SCNN1G COBL TMEM139 NDNF PGGHG NCOR2 LIMCH1 CDH1

1.61e-061842649cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

FNDC1 SCNN1G COBL TMEM139 NDNF PGGHG NCOR2 LIMCH1 CDH1

1.61e-061842649bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCellControl-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

CYP2A6 CYP2A13 ITGA9 SYNJ2 SCNN1G NHS WNK2 GRAMD2B RIMS1

1.68e-0618526496814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCellIPF-Epithelial-Club|World / Disease state, Lineage and Cell class

MAGI1 CYP2A6 EXPH5 ITGA9 SCNN1G GRAMD2B LIMCH1 RIMS1 CDH1

2.19e-0619126493c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 EXPH5 FREM2 COBL MPP7 LRP6 LIMCH1 CDH1 PHACTR1

2.19e-061912649e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GALNT3 EXPH5 HJURP FREM2 PTPRZ1 MPP7 TROAP ZNF804B CDH1

2.28e-06192264925378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellControl-Epithelial-Club|Control / Disease state, Lineage and Cell class

MAGI1 CYP2A6 EXPH5 ITGA9 SCNN1G COBL NHS LIMCH1 CDH1

2.28e-061922649d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EXPH5 EXTL2 CFAP54 PTPRZ1 DLEC1 IQUB MAP3K19 DNAH3 AHNAK2

2.38e-061932649ea345d34440b25f65358a53dc72831998d1c3620
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B EXPH5 FAT2 KCNC4 KCNT1 MPP3 CNTNAP1 NEURL1 RIMS1

2.38e-0619326495fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCellClub_cells|World / lung cells shred on cell class, cell subclass, sample id

CYP2A6 PTPRZ1 SCNN1G WNK2 DDR1 MUC16 GRAMD2B RIMS1 CDH1

2.38e-0619326499d3165dc5763a07a7d873f497624d9d6528fa2db
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 EXPH5 FREM2 COBL MPP7 NDNF LIMCH1 CDH1 PHACTR1

2.38e-061932649a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

MAP1B TRIO F5 FNDC1 PTPRZ1 FLNC PRELP CERCAM AHNAK2

2.71e-06196264924d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellEpithelial-A_(AT1)|World / shred on cell class and cell subclass (v4)

MAGI1 EXPH5 SCNN1G NDNF DDR1 APBB1 TRIM3 LIMCH1 CDH1

2.71e-061962649484bbc6b1f58bc260964babb949d14f5df101393
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LINC00322 SEC24A EML6 CFAP54 MAP3K19 AFF2 TEX14 IGHM IRAG2

2.71e-061962649fd18a9ae8401121ae276adff1a85d5f938e2df91
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAGI1 EXPH5 SCNN1G NDNF DDR1 APBB1 LIMCH1 CDH1 PHACTR1

2.71e-0619626499790340c25f446ec655f5a0b64ec3bb44ed2e1bd
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAGI1 EXPH5 SCNN1G NDNF DDR1 APBB1 LIMCH1 CDH1 PHACTR1

2.71e-061962649b9ceceeacbcf81976ce92adf044f0d0aa132632b
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP2A6 CYP2A13 TRAF3IP1 MMP10 MAP3K19 DNAH3 MUC16 CDH1 AHNAK2

2.82e-0619726495c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|Epithelial / Condition, Lineage and Cell class

CYP2A13 FAT2 PTPRZ1 SCNN1G MMP10 WNK2 ANKRD35 MUC16 RIMS1

2.82e-06197264978ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCellMild_COVID-19-Epithelial-Basal/Club|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CYP2A13 AXIN2 PTPRZ1 SCNN1G MMP10 WNK2 DDR1 MUC16 RIMS1

2.82e-0619726494cc5b778e1e2c6c149160fa147c172977c0fa8eb
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

EXPH5 SCNN1G COBL PLXNB1 MPP3 NDNF CERCAM LIMCH1 CDH1

2.94e-061982649b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MAP1B MAP3K20 IRS1 ITGA9 FNDC1 FLNA PRELP ATRNL1 ATP1A4

3.06e-061992649e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCellBAL-Severe-cDC_10|Severe / Compartment, Disease Groups and Clusters

TRAF1 CD83 PNRC1 KIF2A H6PD CBLB LRCH3 LIMCH1 RUBCN

3.06e-06199264954bdadd04abaf8caa948b0177c037bc089ca07e6
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAP1B ADM AHRR SCNN1G PLXNB3 GPI FLNA FLNC AHNAK2

3.06e-06199264985bb28369e0568b7b3bda095722102fc793f60ef
ToppCellmild-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KIF2A CERK TCF7 DDX60 CBLB CDC14A CCND2 CD2 TLE1

3.06e-061992649cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

EXPH5 SCNN1G COBL PLXNB1 MPP3 NDNF CERCAM LIMCH1 CDH1

3.06e-061992649a270630626df614f8605abddb7dee7c4d74f6149
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

MAP1B MAP3K20 IRS1 ITGA9 FNDC1 FLNA PRELP ATRNL1 ATP1A4

3.19e-062002649c5e051f1aac8dda376c342a9932785a23450e073
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

EXPH5 FAT2 PTPRZ1 HECTD1 PLXNB1 DDR1 ARHGEF12 CDH1 AHNAK2

3.19e-06200264997f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MAP3K20 IRS1 ITGA9 FNDC1 NDNF FLNA PRELP ATRNL1 ATP1A4

3.19e-06200264987827041663013f5e7273168dc8709d69840e7ce
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

MAP3K20 IRS1 ITGA9 PTK7 FNDC1 NDNF FAT4 ATRNL1 RIMS1

3.19e-062002649a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MAP1B MAP3K20 IRS1 ITGA9 FNDC1 FLNA PRELP ATRNL1 ATP1A4

3.19e-062002649c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Intermediate|GW16 / Sample Type, Dataset, Time_group, and Cell type.

HIVEP1 SYNJ2 IQUB AFF2 SHROOM2 CTDP1 CNTNAP2 TREM1 STK40

3.19e-062002649a3fcd901cb281920f1bafdfd676399a6dc37355e
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MAP1B IRS1 FNDC1 FLNA AFF2 GUCY1A2 PRELP ATRNL1 ATP1A4

3.19e-06200264967dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MAP1B MAP3K20 IRS1 ITGA9 FNDC1 FLNA PRELP ATRNL1 ATP1A4

3.19e-062002649dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAGI1 PTPRZ1 VAV2 FAT4 ERICH5 CNTNAP2 LIMCH1 EPB41L2

4.13e-0615526483b8def9e8f66511736ea37f259511f7c8b7743af
ToppCelldroplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMCC2 FAM181B FAT4 CNTNAP1 APBB1 TRABD KCTD20 LIMCH1

7.16e-061672648a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRAF1 CEMIP2 SACS WNK2 TCF7 CDC14A CCND2 CD2

7.16e-06167264883969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell343B-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

TRAF1 EML6 KIF2A TEX14 ORMDL3 LIMCH1 ATP1A4 RUBCN

7.81e-061692648e68e6c24606fd46eca6f86bb63fa86ea17879ae2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B HJURP FNDC1 TROAP E2F8 GUCY1A2 ATRNL1 MYH15

8.52e-061712648b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B HJURP FNDC1 TROAP E2F8 GUCY1A2 ATRNL1 MYH15

8.52e-061712648b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellcritical-Epithelial-unknown_epithelial|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CD83 ADM MTO1 MPP3 FLNA TEX14 TREM1 PHACTR1

9.27e-0617326484144b1cdefa8c37b6ac7a6d249fa5292ffb2b8b2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B MAP3K20 FAM181B MYO18B FLNA FLNC SYNM PRELP

9.27e-061732648ecbf7167d4bec685e3460d826318544946f5f5c2
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRAF1 DLEC1 SEMA4A PTPN18 CCND2 CD2 GRAMD2B CNOT1

9.27e-06173264842272af45547422ef85e35f4a4c7d269e9ed7a8a
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2A13 PTPRZ1 SCNN1G NHS WNK2 MUC16 GRAMD2B RIMS1

9.27e-061732648464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B MAP3K20 FAM181B MYO18B FLNA FLNC SYNM PRELP

9.27e-061732648b8dc978c52de64afba21ff6cb32e79f07167448e
ToppCellASK428-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

EXPH5 EXTL2 GGT5 ARHGAP29 MUC16 IGHM LRP6 RIMS1

1.01e-051752648e0979e5795a49b4e5c9b88e7fe6b7bda7a413a6c
ToppCellClub_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

CYP2A6 GGT5 SCNN1G DDR1 PGGHG GRAMD2B RIMS1 CDH1

1.05e-05176264888c4ed0ab4a4ede8cad21385d799b723b5786cd9
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

F5 PTPRZ1 FAM181B VAV2 AFF2 CCND2 CNTNAP2 LIMCH1

1.05e-05176264805ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCellwk_20-22-Epithelial-Proximal_epithelial-basal_late|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CYP2A13 PHLDA2 FREM2 PTPRZ1 SCNN1G WNK2 TMEM139 FAM181A

1.14e-05178264803f22485074b3cbf9a6ad4d543c5bbfa826dc741
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA9 SCNN1G COBL MPP7 NDNF DDR1 LIMCH1 CDH1

1.19e-05179264804ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellSevere-B_naive-12|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

RPS8 CD83 CEMIP2 PNRC1 PLXNB3 CARMIL1 TLE1 IGHM

1.24e-051802648bc20e581d37cba72b71ef62df60475a0ccee9994
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP1B NDNF FLNA FLNC SPACA9 PRELP RIMS1 AHNAK2

1.29e-051812648ab0f300d14b62cef57f1b0bdae143b8dfe8e6975
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

MAP1B NKRF KCNC4 SYNJ2 GNRH1 JCAD SYNM KIAA1549

1.34e-051822648ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2A13 PTPRZ1 SCNN1G NHS WNK2 MUC16 GRAMD2B RIMS1

1.34e-0518226483f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellIPF-Epithelial-ATI|World / Disease state, Lineage and Cell class

MAGI1 SCNN1G COBL TMEM139 NDNF DDR1 LIMCH1 CDH1

1.39e-05183264831fef35ecf30162662f24d335d8f0cceacc07039
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 F5 FRMD1 SYNJ2 NDNF ARHGEF12 CBLB CDC14A

1.39e-0518326483c516fe5083f02bad1f464ed284010b4131a833c
ToppCellCOVID-19-Heart-CM_4|COVID-19 / Disease (COVID-19 only), tissue and cell type

XIRP1 MAP1B ITGA9 F5 MYO18B MPP3 FLNC SYNM

1.39e-0518326482902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 F5 FRMD1 SYNJ2 NDNF ARHGEF12 CBLB CDC14A

1.39e-0518326489c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_proximal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CYP2A13 FAT2 PTPRZ1 SCNN1G MMP10 DDR1 GRAMD2B FAM181A

1.45e-051842648575de705053da8b289670b5c40c1627c0833b5ed
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

MAGI1 XIRP1 MYO18B FHIT MPP3 FLNC LIMCH1 PHACTR1

1.45e-051842648ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SREBF1 YIPF2 FAT2 SCNN1G SEMA4A ORMDL1 ORMDL2 CDH1

1.45e-051842648382b1e90b3f437af596750669c0465a169d97095
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CCDC125 GALNT3 SIPA1L3 NKRF RCE1 REXO4 IDH2 ORMDL3

1.45e-051842648e6bf826be31e1723e24c366fc5a1cee9b15589bc
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

MAGI1 ITGA9 SCNN1G WNK2 GRAMD2B LIMCH1 RIMS1 CDH1

1.51e-051852648cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellControl-Epithelial_alveolar|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA9 COBL MPP7 MPP3 NDNF CARMIL1 LIMCH1 CDH1

1.51e-0518526483937e026add96a396122139daf8011cfbc60e75c
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA9 SCNN1G COBL MPP7 MPP3 NDNF DDR1 CDH1

1.51e-051852648c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MAGI1 EXPH5 FREM2 WNK2 KIAA1549 C10orf90 WDR97 CDH1

1.51e-051852648636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAP1B IRS1 ITGA9 FNDC1 FLNA PRELP ATRNL1 RIMS1

1.57e-0518626486add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCellCOPD-Epithelial-ATI|COPD / Disease state, Lineage and Cell class

MAGI1 SCNN1G COBL TMEM139 NDNF DDR1 LIMCH1 CDH1

1.57e-051862648df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B EXPH5 FAT2 KCNC4 KCNT1 MPP3 CNTNAP1 RIMS1

1.57e-051862648d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA9 SCNN1G COBL MPP7 MPP3 NDNF LIMCH1 CDH1

1.57e-0518626484e94158db52df41d71e67b02b9895a358eebee0f
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GALNT3 EXPH5 FREM2 PTPRZ1 MPP7 C10orf90 E2F8 CDH1

1.57e-051862648bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GALNT3 EXPH5 FREM2 PTPRZ1 MPP7 C10orf90 E2F8 CDH1

1.63e-051872648db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellCOVID-19_Mild-Neu_4|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

HJURP GPI IDH2 SHQ1 CCND2 SNX14 CD2 TMPO

1.63e-051872648714851e757c71c559ee6413a3f61d6c117c79ad2
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

EXPH5 ITGA9 LRCH1 FREM2 NHS JCAD PGGHG CABIN1

1.63e-0518726487e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellIPF-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

NCOA3 TRIO SIPA1L3 CD83 VAV2 CARMIL1 IGHM PHACTR1

1.63e-051872648af1327559f7e01bec070881cae52834917c3da65
DrugAceclofenac [89796-99-6]; Up 200; 11.2uM; PC3; HT_HG-U133A

NCOA3 HIVEP1 LRCH1 CEMIP2 PLXNB1 BICRA SPACA9 SHROOM2 CDC14A NCOR2 CTDP1 MYH15

2.84e-06196260127269_UP
DrugN'-nitrosoanatabine

CYP2A6 CYP2A13 UGT2B10

5.84e-0642603ctd:C032978
Drugpolybrominated biphenyl

CYP2A6 CYP2A13 CYP2D6 GGT5 AHRR IDH2

1.03e-05442606CID000042948
Drug2-phenylindole

ESRRA PHLDA2 TAF1 TKT

1.10e-05132604CID000013698
DrugNadolol [42200-33-9]; Up 200; 13uM; MCF7; HT_HG-U133A

TRAF3IP1 SEC24A ADM SYNJ2 PLXNB1 TEX14 CDC14A NCOR2 MED25 LIMCH1 AHNAK2

1.52e-05194260114139_UP
DrugHydrocortisone base [50-23-7]; Up 200; 11uM; MCF7; HT_HG-U133A

KMT2B TRAF3IP1 FRMD1 ADM VAV2 JCAD FAT4 GSDMD ATRNL1 NEURL1 MED25

1.52e-05194260113284_UP
DrugFluorometholone [426-13-1]; Up 200; 10.6uM; MCF7; HT_HG-U133A

TRIO ITGA9 FRMD1 MAN1A2 PLXNB1 H6PD CRAT GUCY1A2 BAZ2A CNTNAP2 MED25

1.60e-05195260116071_UP
DrugSulfanilamide [63-74-1]; Down 200; 23.2uM; PC3; HT_HG-U133A

ABCA2 TRAF3IP1 SIPA1L3 APBB1 H6PD SHROOM2 CDC14A BAZ2A MED25 TMPO LRP6

1.76e-05197260114474_DN
DrugCarbinoxamine maleate salt [3505-38-2]; Up 200; 9.8uM; HL60; HT_HG-U133A

TRAF1 MAN1A2 TMCC2 SYNM SPACA9 CDC14A TRIM3 TLE1 NEURL1 KCTD20 RIMS1

1.84e-05198260112725_UP
DrugOxaprozin [21256-18-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A

MAGI1 FRMD1 MPP3 ARHGEF12 CDC14A TRIM3 NCOR2 LRP6 DEPDC5 LIMCH1 AQR

1.84e-05198260113876_DN
DrugAcenocoumarol [152-72-7]; Up 200; 11.4uM; PC3; HT_HG-U133A

NCOA3 SYNJ2 PLXNB1 APBB1 NSD1 SPACA9 ATP13A2 GSDMD NEURL1 CNTNAP2 CABIN1

2.02e-05200260112077_UP
DrugN'-nitrosoanabasine

CYP2A6 CYP2A13 UGT2B10

2.87e-0562603ctd:C010257
DiseaseMalignant neoplasm of breast

NCOA3 XIRP1 ADAT3 MAN2C1 CYP2D6 ESRRA RPS8 ITGA9 SYNJ2 ARHGAP29 NHS DLEC1 MMP10 PLXNB1 RCE1 GPI FLNA H6PD SHROOM2 CD2 GUCY1A2 TREM1 CDH1 PADI3

1.90e-05107425224C0006142
Diseasecotinine measurement, cigarettes per day measurement

CYP2A6 UGT2B10

7.27e-0522522EFO_0006525, EFO_0007813
DiseaseColorectal Carcinoma

CYP2A6 MAP1B F5 AXIN2 SACS MCM3AP SCNN1G UNG IQUB FLNC DNAH3 CDC14A CCND2 GMCL2 GUCY1A2 NEURL1 CDH1

1.26e-0470225217C0009402
DiseaseNeurodegeneration with brain iron accumulation

TBCE CRAT ATP13A2

1.65e-04132523cv:C2931845
Diseasemyofibrillar myopathy 5 (implicated_via_orthology)

FLNA FLNC

2.17e-0432522DOID:0080096 (implicated_via_orthology)
Diseasedistal muscular dystrophy 4 (implicated_via_orthology)

FLNA FLNC

2.17e-0432522DOID:0111190 (implicated_via_orthology)
Diseaseaspartate aminotransferase measurement

CCDC125 MAGI1 CYP2A6 WWC3 PEPD PHLDA2 ITGA9 TMCC2 ARHGAP29 VARS1 WNK2 CARMIL1 NSD1 PTPN18 NCOR2 NPHP3 BAZ2A CNTNAP2 HMGXB3

3.10e-0490425219EFO_0004736
Diseasehematological measurement

F5 MYH15

4.31e-0442522EFO_0004503
DiseaseKDEL motif-containing protein 2 measurement

POGLUT3 EXPH5

4.31e-0442522EFO_0801740
Diseaseinvasive lobular carcinoma (is_implicated_in)

CCND2 CDH1

4.31e-0442522DOID:3457 (is_implicated_in)
Diseasesquamous cell lung carcinoma

CYP2A6 ELAC2 COBL VARS1 REXO4 CARMIL1 RIMS1

5.64e-041652527EFO_0000708
Diseaseacute myeloid leukemia (is_implicated_in)

CYP2D6 DLEC1 NSD1 IDH2 CDH1

7.78e-04842525DOID:9119 (is_implicated_in)
Diseaseplatelet component distribution width

IRS1 LRCH1 SYNJ2 CRLF3 TMCC2 KIF2A DLEC1 VAV2 MPP3 JCAD CARMIL1 U2SURP ZNF496 NCOR2 MEIOC BAZ2A

8.43e-0475525216EFO_0007984
Diseasecotinine measurement

CYP2A6 UGT2B10 CNTNAP2

9.61e-04232523EFO_0007813
Diseaseperiventricular nodular heterotopia (is_implicated_in)

MAP1B FLNA

1.07e-0362522DOID:0050454 (is_implicated_in)
Diseasemigraine disorder

HJURP LRCH1 EHMT2 JCAD NSD1 NCOR2 HMGXB3 LIMCH1 EPB41L2 PHACTR1

1.07e-0335725210MONDO_0005277
Diseasemyeloid white cell count

CCDC125 TRAF1 POGLUT3 RC3H1 EML6 NAIP PEPD SREBF1 EXTL2 NCLN GGT5 VAV2 PLXNB1 JCAD ARHGEF12 CBX4 CDC14A ATP1A4

1.24e-0393725218EFO_0007988
DiseaseGemistocytic astrocytoma

NCOA3 KIAA1549 IDH2

1.38e-03262523C0334581
DiseaseProtoplasmic astrocytoma

NCOA3 KIAA1549 IDH2

1.38e-03262523C0334580
DiseaseFibrillary Astrocytoma

NCOA3 KIAA1549 IDH2

1.38e-03262523C0334582
DiseaseAdenocarcinoma of large intestine

TRRAP AXIN2 PTK7 TAF1 STK40

1.42e-03962525C1319315
DiseaseHelicobacter Infections

PTPRZ1 CDH1

1.48e-0372522C0079487
Diseasemyoclonic-atonic epilepsy (implicated_via_orthology)

VARS1 SLC25A10

1.48e-0372522DOID:0060475 (implicated_via_orthology)
DiseaseAutosomal Dominant Nocturnal Frontal Lobe Epilepsy

KCNT1 DEPDC5

1.48e-0372522C3696898
DiseasePeriventricular Nodular Heterotopia

MAP1B FLNA

1.48e-0372522C1868720
Diseasecolon adenoma (is_marker_for)

AXIN2 CCND2

1.48e-0372522DOID:0050912 (is_marker_for)
DiseaseAnaplastic astrocytoma

NCOA3 KIAA1549 IDH2

1.55e-03272523C0334579
Diseaseblood cobalt measurement

F5 FRMD1 NDNF MUC16 CDC14A

1.78e-031012525EFO_0007577
Diseasenasopharyngeal neoplasm

CYP2A6 IRS1 ITGA9 CNTNAP2 IRAG2 HMGXB3

1.94e-031512526EFO_0004252
DiseaseQT interval, response to tricyclic antidepressant

CCND2 CNTNAP2

1.97e-0382522EFO_0004682, EFO_0007916
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP1 CNTNAP2

1.97e-0382522DOID:0060308 (implicated_via_orthology)
Diseaseoral squamous cell carcinoma (is_marker_for)

NAIP AXIN2 DDR1 CDH1

2.08e-03632524DOID:0050866 (is_marker_for)
DiseaseLung Neoplasms

CYP2A6 EHMT2 MMP10 FHIT DDR1 SOX30 RICTOR CCND2

2.10e-032652528C0024121
DiseaseMalignant neoplasm of lung

CYP2A6 EHMT2 MMP10 FHIT DDR1 SOX30 RICTOR CCND2

2.15e-032662528C0242379
DiseaseTendinopathy

MPP7 CNTNAP2

2.51e-0392522EFO_1001434
DiseaseCleft palate with cleft lip

ARHGAP29 CDH1

2.51e-0392522C0158646
Diseaseresponse to aromatase inhibitor

CYP2A6 MUC16 CNOT1

2.54e-03322523GO_0061477
DiseaseColorectal Neoplasms

CYP2A6 AXIN2 UNG FLNC CCND2 GUCY1A2 NEURL1 CDH1

2.75e-032772528C0009404
DiseaseSpinocerebellar Ataxia Type 2

SNX14 PRKCG RUBCN

3.03e-03342523C0752121
DiseaseSpinocerebellar Ataxia Type 1

SNX14 PRKCG RUBCN

3.03e-03342523C0752120
DiseaseSpinocerebellar Ataxia Type 5

SNX14 PRKCG RUBCN

3.03e-03342523C0752123
DiseaseSpinocerebellar Ataxia Type 7

SNX14 PRKCG RUBCN

3.03e-03342523C0752125
DiseaseSpinocerebellar Ataxia Type 6 (disorder)

SNX14 PRKCG RUBCN

3.03e-03342523C0752124
DiseaseAtaxia, Spinocerebellar

SNX14 PRKCG RUBCN

3.03e-03342523C0087012
Diseasemitochondrial complex I deficiency (implicated_via_orthology)

ELAC2 SLC25A10

3.12e-03102522DOID:0060536 (implicated_via_orthology)
DiseaseUterine leiomyoma, estrogen-receptor negative breast cancer

POGLUT3 EXPH5

3.12e-03102522EFO_1000650, HP_0000131
Disease3-methyl-2-oxobutyrate measurement

GPI FAT4

3.12e-03102522EFO_0021020
DiseaseSpinocerebellar Ataxia Type 4

SNX14 PRKCG RUBCN

3.29e-03352523C0752122
Diseaseasthma (implicated_via_orthology)

ORMDL1 ORMDL3 ORMDL2

3.29e-03352523DOID:2841 (implicated_via_orthology)
DiseasePolydactyly

TRAF3IP1 FREM2 CCND2 C2CD3 NPHP3

3.37e-031172525C0152427
Diseasepentachlorophenol measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022071
Diseaseparathion measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022070
Diseasepotassium chromate measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022072
Diseasemercuric chloride measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022068
Diseaseheptachlor epoxide measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022067
Diseasemethoxychlor measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022069
Disease4,6-dinitro-o-cresol measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022053
Disease2,4,5-trichlorophenol measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022052
Diseaseazinphos methyl measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022055
Diseasealdrin measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022054
Diseasedicofol measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022060
Diseasedisulfoton measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022062
Diseasedieldrin measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022061
Diseaseendrin measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022064
Diseaseendosulfan measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022063
Diseaseheptachlor measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022066
Diseaseethion measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022065
Diseasechlorpyrifos measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022057
Diseasecadmium chloride measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022056
Diseasediazinon measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022059
Diseasedibutyl phthalate measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0022058
Diseaseenvironmental exposure measurement

F5 FRMD1 MUC16 CDC14A

3.56e-03732524EFO_0008360
Diseaselung squamous cell carcinoma (is_marker_for)

SOX30 IDH2 CBLB

3.57e-03362523DOID:3907 (is_marker_for)
Diseaselung cancer (is_implicated_in)

AXIN2 SOX30 RICTOR IDH2

3.74e-03742524DOID:1324 (is_implicated_in)
DiseaseDDT metabolite measurement

F5 FRMD1 MUC16 CDC14A

3.74e-03742524EFO_0007886
Diseaseblood nickel measurement

F5 FRMD1 FAT2 MUC16 CDC14A

3.75e-031202525EFO_0007583
Diseasemelanoma-derived growth regulatory protein measurement

CYP2A6 NUMBL

3.80e-03112522EFO_0008229
Diseaseinterleukin-6 measurement, response to stimulus

CARMIL1 MUC16

3.80e-03112522EFO_0004810, GO_0050896
DiseaseLeukemia, Myelocytic, Acute

TRIO EHMT2 NSD1 IDH2 CBLB CCND2

3.81e-031732526C0023467
DiseaseRheumatoid Arthritis

PADI4 TRAF1 CD83 MMP10 CD2 TMPO

3.92e-031742526C0003873
DiseaseAcute Myeloid Leukemia, M1

TRIO EHMT2 NSD1 IDH2 CCND2

4.46e-031252525C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

TRIO EHMT2 NSD1 IDH2 CCND2

4.46e-031252525C1879321
DiseaseOligodontia

AXIN2 LRP6

4.53e-03122522C4082304
DiseaseRenal dysplasia and retinal aplasia (disorder)

TRAF3IP1 NPHP3

4.53e-03122522C0403553
Diseasestomach carcinoma (is_implicated_in)

CBLB CCND2

4.53e-03122522DOID:5517 (is_implicated_in)
Diseasehepatocellular carcinoma (is_marker_for)

AXIN2 DDR1 SOX30 RICTOR CBX4 IDH2 CCND2 CDH1

4.54e-033012528DOID:684 (is_marker_for)
DiseaseInherited neuropathies

SACS WASHC5 PRKCG

4.82e-03402523C0598589
Diseasebilirubin measurement

SIPA1L3 HJURP PHLDA2 UGT2B10 FAT4 CARMIL1 CRAT CCND2 ORMDL1 PHACTR1

4.96e-0344225210EFO_0004570
DiseaseMesothelioma

MYO18B FHIT CDH1

5.16e-03412523C0025500
Diseasegallbladder cancer (is_implicated_in)

AXIN2 RICTOR

5.33e-03132522DOID:3121 (is_implicated_in)
DiseaseIntellectual Disability

GALT MAP1B TRIO TRRAP SACS TAF1 NSD1 SNX14 PRKCG PHACTR1

5.36e-0344725210C3714756
DiseaseCardiomegaly

IDH2 SIRT6 CCND2 CABIN1

5.40e-03822524C0018800
DiseaseCardiac Hypertrophy

IDH2 SIRT6 CCND2 CABIN1

5.40e-03822524C1383860
Diseasetotal blood protein measurement

NCOA3 PEPD CEMIP2 ARHGAP29 DNAH3 TCF7 ARHGEF12 CCND2 NCOR2 SLC25A10

5.52e-0344925210EFO_0004536
DiseaseMammary Carcinoma, Human

NCOA3 MAN2C1 CYP2D6 ESRRA RPS8 SYNJ2 GPI FLNA H6PD GUCY1A2 CDH1

5.78e-0352525211C4704874
DiseaseMammary Neoplasms, Human

NCOA3 MAN2C1 CYP2D6 ESRRA RPS8 SYNJ2 GPI FLNA H6PD GUCY1A2 CDH1

5.78e-0352525211C1257931
DiseaseMammary Neoplasms

NCOA3 MAN2C1 CYP2D6 ESRRA RPS8 SYNJ2 GPI FLNA H6PD GUCY1A2 CDH1

5.94e-0352725211C1458155
DiseaseParkinson Disease

CYP2D6 RPS8 ATP13A2 CNTNAP2

6.13e-03852524C0030567
Diseasedystonia (is_implicated_in)

KMT2B SHQ1

6.18e-03142522DOID:543 (is_implicated_in)
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

FLNC NPHP3

6.18e-03142522DOID:898 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
KVTPRAQRPGAHAED

PTPN18

391

Q99952
ARKRHAPSPEPAVQG

UNG

16

P13051
ERPSKNSHPVQVGRI

TREM1

71

Q9NP99
IHFPIRGNKTSPRAH

NAIP

916

Q13075
HSEDGARPRLQPSKN

AHRR

411

A9YTQ3
PGERPSHSLSRDFKN

C2orf16

1946

Q68DN1
AQPHLKRVRPSRDAG

ADAT3

71

Q96EY9
FSGLHPTNFPIEKTR

CTDP1

641

Q9Y5B0
REARRANPHFKSFPV

BRWD1-AS2

76

P59051
ANPHFKSFPVLEARG

BRWD1-AS2

81

P59051
RKPDGSRHQDVPSQD

AASDHPPT

246

Q9NRN7
PKGLTENSRHRLTPQ

ARID5A

301

Q03989
FQGLLRTTLPHPKAE

CFAP54

2026

Q96N23
NNVAPLKTHFRTPRP

CNTNAP1

1216

P78357
IDVSPKHVGFATIPR

CYP2A6

471

P11509
LGHSDFPTTVPRLAK

ALS2

591

Q96Q42
TKGHPRAVSQPFRLS

CDC14A

421

Q9UNH5
QPRHLKSPVRGQDSE

BAZ2A

1201

Q9UIF9
VELHDPPRGRNKATA

AFF2

661

P51816
VATEERGRKPHQIPA

CD2

256

P06729
VSLDFPLNVRKGHPL

DDR1

636

Q08345
KQRTFQPPATGHKRS

GSDMD

236

P57764
TPKFSIQRHSPLGFA

FAT4

4646

Q6V0I7
APRSHGPTVRKFAKV

AJM1

836

C9J069
EPRSRDLSPISKGFH

CACNG3

241

O60359
VKANGQVSLPHFPRT

AXIN2

341

Q9Y2T1
SRFKAHQDALPRLPV

CRAT

26

P43155
LDGKRQRFHSPHQEP

TENT2

86

Q6PIY7
TTSPEGQPKVHRARK

EHMT2

171

Q96KQ7
QRKALSHVPGAARPF

CCDC142

216

Q17RM4
RPQALTDGPREHSKS

APBB1

191

O00213
EPFPTTRKNGERPSH

AQR

1336

O60306
RPTKLDSNGQSPFHL

ANKRD35

46

Q8N283
RDRVAKGSQGPLPFH

SLC25A10

86

Q9UBX3
HKEQPVRGSTFPSNL

ATG2B

466

Q96BY7
QGSLFPSPILRAKHF

ATP10D

1321

Q9P241
RTLVSSKPQAHGAPA

ADM

161

P35318
KPIRHGSILNRESPT

ARHGEF12

16

Q9NZN5
DGTRDHQFPAKRPRL

HJURP

671

Q8NCD3
HQFPAKRPRLSEPQG

HJURP

676

Q8NCD3
AFQPGHKRTPSEAER

NUMBL

401

Q9Y6R0
EPRFPQASKTSIGHV

RC3H1

231

Q5TC82
ISLFRAAVPHTGRKN

NPFFR2

346

Q9Y5X5
ESRHGAVKSPFLPLA

NSD1

216

Q96L73
TTPGFRIPLKNAHDA

PCDHGA2

146

Q9Y5H1
GKSTLFVPRLPASHA

PEPD

91

P12955
QVKGSRRPKFHARPE

RIMBP3B

716

A6NNM3
QVKGSRRPKFHARPE

RIMBP3C

716

A6NJZ7
ARPTGFIHTLKEPQI

IQCJ

136

Q1A5X6
KPPREGTLQHAFLRE

NCLN

326

Q969V3
HDFGLRTPPLIRTQK

PARP2

311

Q9UGN5
PSKNVRHRGRVSPSD

KIAA1549

1401

Q9HCM3
RFLAGVPTPKSHLQL

CCND2

86

P30279
ERAFLPVTSPNKHLG

CD83

181

Q01151
HTLGFPPTIRKIDAA

MMP10

376

P09238
HKTLPVVFDSPRNRG

PADI4

361

Q9UM07
AVPLFKLHNRSAPRD

DEPDC5

376

O75140
IPNEAAHRGTIRPVK

MUC16

10436

Q8WXI7
ERPRADTGHAFLAKP

NCOR2

1946

Q9Y618
PFETPDQGKARLLTH

ORMDL2

71

Q53FV1
KPARIVAGHEPERTN

TRAF3IP1

91

Q8TDR0
GVRRSFRKSPEHPVD

KIAA0100

2086

Q14667
GDSRSQKPELQPHRS

KRBA1

416

A5PL33
QRRISHEGSPVKPVA

LRCH3

411

Q96II8
HSARFSPEVPGQKIL

MAP1B

86

P46821
NFDVGHVPIRLPRTK

METAP2

386

P50579
ANLKQDAGRSSRHPP

MAGI1

1461

Q96QZ7
KVPPGSRATFQVEHL

MGA

2866

Q8IWI9
LRQDPKTGSFPEHIT

GPR179

1916

Q6PRD1
GNKRNHEPFIAPERF

KCTD20

86

Q7Z5Y7
PSIESKVLRFPNRLH

MTO1

316

Q9Y2Z2
PEAQHRKTPTFLGAT

ENTPD8

111

Q5MY95
FPTGDHKQRPSARNL

JCAD

736

Q9P266
ARRQGHVNLPPLEFK

KIAA1109

2496

Q2LD37
APVGSPALKREHFQV

FREM2

291

Q5SZK8
REGRLAIKPFHPSAN

MCM3AP

1806

O60318
REDNKSILLNPGPRH

KCNT1

581

Q5JUK3
GDPAEHPLLRRKSLQ

KCNT1

1071

Q5JUK3
IKSNVPELRGHFPLS

DDX60

1351

Q8IY21
PHNKPLFQALIDGSR

CBLB

311

Q13191
PDQIVGFVPRKHVST

EXTL2

171

Q9UBQ6
DGRREVRSPTKAPHL

EPB41L2

591

O43491
ARAIRPPRHFTGGKI

HMGXB3

1046

Q12766
PRDHPAVIKRRFTSV

RCE1

61

Q9Y256
KVRASPAGQLPSRFH

PNRC1

101

Q12796
DPKVHSIFPARGPRA

PLXNB1

1161

O43157
KGTPFSQRPSVHALD

PLXNB3

1561

Q9ULL4
QIRGFHLPPSKLSSL

FAT2

346

Q9NYQ8
PRRPFLGSHSVDKSQ

PEAK3

86

Q6ZS72
IFKHGTVASRPPVQI

CRLF3

171

Q8IUI8
PAGTSEPHRALKRQA

FAM214B

56

Q7L5A3
EPHRALKRQAPSTEG

FAM214B

61

Q7L5A3
AEAHIPGSPFKATIR

FLNC

1136

Q14315
LPNRHIGISFTPKEV

FLNC

1996

Q14315
ANPRAGLIPSKHFQE

MPP7

281

Q5T2T1
RPLEPRADQHTFGSK

RIPPLY3

56

P57055
RQRLGKRPHSPEKAF

NCBP3

491

Q53F19
RQAVVKGSLPHPFAL

LRP6

216

O75581
RKLKEFPRTAAPGHD

LRCH1

81

Q9Y2L9
RSFQAKPSPKLGRHV

NDNF

266

Q8TB73
PAKDVSPRRHVATIF

EXPH5

1606

Q8NEV8
RGIHFSIVSPRKLPA

MED25

176

Q71SY5
RNLEPHGKQPSLRAA

METTL18

86

O95568
RLLPHKVFEGNRPTN

GPI

461

P06744
APKRTGPHLRFEISS

KMT2B

2406

Q9UMN6
NRVTGNFKHASPILP

TMPO

296

P42167
GPQTDDPRNKHKFRL

PRKCG

91

P05129
QSRLSLLPGHKVSFP

PGGHG

666

Q32M88
TVAAPAHGKAAPRRE

FAM181B

136

A6NEQ2
PKGRHVFATPVLSID

PTPRZ1

1306

P23471
FTPHDNEPGKGRLVR

PAXBP1

241

Q9Y5B6
HKTLPVVFDSPRNGE

PADI3

361

Q9ULW8
SLPRSFKHTQRPGEP

IRS1

766

P35568
PFETPDQGKARLLTH

ORMDL1

71

Q9P0S3
QTKNIPPHDDRGARA

RICTOR

1446

Q6R327
PGTRKIELFGRPHNV

METTL3

526

Q86U44
AHERRLPAGPKVNRT

KIR2DS5

166

Q14953
GTHTPPIRRRSKFAN

PHACTR1

101

Q9C0D0
HAAPRATDQPVIRGK

RIMS1

1196

Q86UR5
ATDQPVIRGKHPARS

RIMS1

1201

Q86UR5
PGAVFKCRVHTNPDR

ITGA9

81

Q13797
GRNKPHTPFRASKLT

KIF2A

496

O00139
ESISPGDFHRKLPRT

ARHGAP29

556

Q52LW3
PKRFTAQGLPDLNHS

UPF1

471

Q92900
PTLHRERQGLSPKEA

FRMD1

231

Q8N878
GLVSSILHPRPINFK

ATP13A2

406

Q9NQ11
QGSSFALPQKRPHPR

FCAMR

11

Q8WWV6
LSFALVNRKPVVPGH

FHIT

21

P49789
RFTRRGVDPAPLAKH

HECTD1

216

Q9ULT8
REHQKGRPTSTNPIA

IDH2

356

P48735
HRSRKRSDGKNFSPP

CCDC125

46

Q86Z20
VQRPSDAHTKPRPAL

CABIN1

1956

Q9Y6J0
HKGPPIDSSDIRQRQ

C2CD3

2241

Q4AC94
IDVSPKHVGFATIPR

CYP2A13

471

Q16696
NLFSTRGKPNFTRHP

E2F8

381

A0AVK6
QTISRPKGVALHRPD

IGHM

316

P01871
RRGEASPKAPNHFRK

DMRTC2

101

Q8IXT2
HPGPAFQRSKARETQ

DNAH3

16

Q8TD57
QPGSVGRLHFPKLRS

LINC00322

151

Q6ZN03
APQDFHPDRVKARGP

FLNA

666

P21333
FLPAQHTVGSPRDRK

CERK

331

Q8TCT0
NHSGRPFRPNGLLDK

CYP2D6

166

P10635
SPHSFPKGTQVIARN

GALNT3

421

Q14435
RSPQRGASLHRKEPI

FNDC1

911

Q4ZHG4
KAQPGSTDRHASPAR

FNDC1

966

Q4ZHG4
PSDHPLFQAKSARGV

GALT

111

P07902
GPHRKLSTQDRPAAI

COBL

956

O75128
APLRGRHTLSQVPNK

LINC02898

56

Q6ZV80
ERHPPADRTFKKAAG

CBX4

301

O00257
RPQELKLCFSRHPTG

DENND4C

721

Q5VZ89
LGDPRSHPKLQNASR

GGT5

336

P36269
SVIFQTRKDGSLPPH

ABCA2

606

Q9BZC7
PKPNLHRDVNRFGHS

ATRNL1

571

Q5VV63
PRNNISLVKFGPHVS

CEMIP2

911

Q9UHN6
NAPVHRLLSRQGTPK

CCP110

956

O43303
ALNPHQSPDFKRSPR

MAP3K20

721

Q9NYL2
QSPDFKRSPRDLHQP

MAP3K20

726

Q9NYL2
PDPAGHLTLRDNRLK

MAN2C1

1006

Q9NTJ4
RPIARKGHSPNIFGS

MAN1A2

206

O60476
HNAGTQTVPKRIPER

IQUB

266

Q8NA54
SPNKHVSVPDRITGR

ASNSD1

396

Q9NWL6
PAPGQIALLKFSSHR

DND1

176

Q8IYX4
RILGSKQSEHRPSLP

IRAG2

406

Q12912
RTVFSHRKGKEVPPS

CARMIL1

401

Q5VZK9
LPQQIRKAPTEGHTR

CNTNAP2

901

Q9UHC6
FFEAPRGKRHIIRPS

EML6

1151

Q6ZMW3
HQPRSPLRDLKGALE

GNRH1

66

P01148
HVTRPSKRPSKIGFD

CERCAM

306

Q5T4B2
FAQPKPHALGRESTV

ERICH5

36

Q6P6B1
KPTRADAHVNRVPEG

GRAMD2B

301

Q96HH9
RRELQKPDSFHSLTP

H6PD

321

O95479
NEKSLPQHRFPATGL

BMP2KL

131

Q5H9B9
PKALLERFHQVPSGI

BICRA

956

Q9NZM4
PGKRHRLQDFAVGPL

DLEC1

1441

Q9Y238
DKIRDGLHRPSSTPN

ERVFC1

491

P60507
RPAANTKIGPRRIHT

RPS8

31

P62241
RKPQESRGHVSPAED

RUBCN

256

Q92622
GPAHTKPLNRRSVLE

S100PBP

126

Q96BU1
RAFILHKADPVPNGL

SLC20A1

181

Q8WUM9
VSEGKQPRFSHRIPL

SCNN1G

146

P51170
RPAQAIGTQPRATKH

SPACA9

181

Q96E40
TLRVKGFNPIPHSRS

SACS

4056

Q9NZJ4
GPRKTAAPVNALVSH

ESRRA

186

P11474
PTRSGVLTIPQNHKF

MAP3K19

216

Q56UN5
GVITVKRPLRFHNPQ

CDH1

81

P12830
ERRKKSPREHFQAGP

LIMCH1

976

Q9UPQ0
PFETPDQGKARLLTH

ORMDL3

71

Q8N138
SHRVLSGTAPKDPRQ

PTX4

241

Q96A99
TAHRKVPGAQLPTAA

OSBPL7

156

Q9BZF2
APTNHRRPGEKRAST

FAM181A

16

Q8N9Y4
QHFGVAVPHTTRPRK

MPP3

411

Q13368
KFESGSHPRRINVSP

GUCY1A2

646

P33402
RAPVPRTKASGTEHN

REXO4

141

Q9GZR2
GKNVIHPFLSRSLPI

VARS1

561

P26640
QRPIKTRSGPASELH

MEIOC

741

A2RUB1
HPFTNKPTTFRGLRP

MRPL43

131

Q8N983
KRQFGSAPPVRRLGH

STK40

401

Q8N2I9
LPGVPKSRLEHETNR

TMC3

806

Q7Z5M5
GSFTSIRHPSPRQKE

TEX14

1026

Q8IWB6
HRKPSPATRDGIIVN

TBC1D31

16

Q96DN5
TSRRDFGPHKVAPVK

SAXO1

71

Q8IYX7
QRGSPHLLRKAPQDS

TMCC2

191

O75069
LPRHTFGLVQSKLFP

TMEM205

41

Q6UW68
HGQPSPSLEDAKLRR

TMEM126B

36

Q8IUX1
RTLRHIAPGPKETSF

SYNM

1446

O15061
TFQPGKAAERPSHRK

SYNJ2

1291

O15056
SGHPKFPRVRHKSLQ

F5

996

P12259
DHKRQGRPSISFRKP

NHS

831

Q6T4R5
QAGSKFHARPRFEPV

NKRF

46

O15226
IRQKSFGPKHPSVAT

NPHP3

1206

Q7Z494
QVKGSRRPKFHARPE

RIMBP3

716

Q9UFD9
VGALKPREEPNHRSS

SEC24A

646

O95486
VPGPNSKRANTHIRD

TAF1

791

P21675
KGKRRSEAPPHIFAV

MYH15

161

Q9Y2K3
HSKRPRFLAPNQASG

PRR20G

6

P0DPQ3
TEPGKPFVSVFRHLR

GMCL2

321

Q8NEA9
NRGSPKIASHQFSPV

NCOA3

486

Q9Y6Q9
TLRPGEKAPLSREQH

SEMA4A

721

Q9H3S1
GALPFTPKNIRSHFQ

SIPA1L3

731

O60292
PFRESQPLHSKRPVS

SIPA1L3

1121

O60292
SPFGSIHPRDKQTVA

SIAE

371

Q9HAT2
IFTIRLPKETPGQHF

SHQ1

71

Q6PI26
PFDAHVGKPTRRSDR

SHROOM2

611

Q13796
NHISRIPPGVFSKLE

PRELP

181

P51888
FPFPRIVVGATLHSK

SEC31B

796

Q9NQW1
EKRGLQRRATPHPSE

SCRIB

466

Q14160
PREPHTKAPRGFAFV

SRSF8

46

Q9BRL6
AQHNGSEPASPKRER

SIRT6

321

Q8N6T7
DTPFSKDRNGHVKRP

SOX30

326

O94993
SERPLPRAALHSFKA

SREBF1

911

P36956
RHKTKGRLSRFEPPQ

U2SURP

221

O15042
QVHIPSLGFAKPDLR

AHNAK2

5091

Q8IVF2
KKGTVAPHDQSPRRR

ATP1A4

6

Q13733
EQKPTRHFLPIGDSS

C10orf90

441

Q96M02
NTFHILRPTKAPGFV

CNOT1

2021

A5YKK6
QKERETPPRFAQHGT

SFPQ

471

P23246
RIHVPKPLDRNDGTF

POGLUT3

86

Q7Z4H8
HFKKVRGPSRADPNH

VPS4B

361

O75351
RASPAHSPRENGIDK

TLE1

261

Q04724
KHLRVLPAAGPTAFS

ZNF804B

1176

A4D1E1
ALHRGLIFNPRAKPS

WASHC5

721

Q12768
SHGQLKSVPQRTDFP

ZNF19

116

P17023
QRERALASLGKPLHP

ELAC2

561

Q9BQ52
IKAGPFHSERRPSQS

MPDZ

1806

O75970
LRLGFTSKDPSRIHP

NEURL1

121

O76050
HLAVNRVPRSGKPAE

TKT

586

P29401
RLHQEAPSNSGKPSR

SPEM3

1176

A0A1B0GUW6
HGAFPDAQLPSKRII

SNX14

631

Q9Y5W7
CRHPTGGSFIRPNKV

TBCE

61

Q15813
FHLGDRPIPVTFKRA

TRABD

186

Q9H4I3
SSLRGFFPATVQPHK

WDR97

1021

A6NE52
SVPHLPEKQATGRFE

SNX18

331

Q96RF0
RPQSRGAHLFPEKLE

THSD1

696

Q9NS62
AGPRPKARHQAETSQ

TROAP

66

Q12815
HRSFPVRERTHPGGK

ZNF627

151

Q7L945
SPGSRLRTQEKAHPE

TRAF1

66

Q13077
KHPVIPQGTASLRFS

TEX13C

881

A0A0J9YWL9
FKRKPHTNGDAPSHR

TBC1D15

106

Q8TC07
ESSPRPHRIAGVKRF

nan

46

Q6ZVQ6
GREHAAQRLFPDKLP

TCF7

86

P36402
KQVHRPLQTPDLSGF

TCF7

181

P36402
ASPRARPKELRFHSI

PHLDA2

41

Q53GA4
TSGDKPVSPHFVRRQ

MYO18B

2186

Q8IUG5
TTRSPRHPGVIFKAL

ZFYVE1

386

Q9HBF4
GSPTEKQRSLPASHR

ZNF496

376

Q96IT1
HPSFRTPQRDHTGEK

ZNF69

176

Q9UC07
IPQNDLLGHPKTRAF

UGT2B10

356

P36537
EGHVKQVSPRRPQAT

THAP3

141

Q8WTV1
SLHSIAQNKGIRPFP

VAV2

116

P52735
VGFFHTAPPTGRRRK

WNK2

1971

Q9Y3S1
DRIKGSLLPRPGHNF

YIPF2

96

Q9BWQ6
KERNLTLRPAGPEHS

PTK7

181

Q13308
GSPFREPLIKFLTRH

TRRAP

1551

Q9Y4A5
HQRGERDTAIPQPAK

XIRP1

1361

Q702N8
RKSPSERHVLGQPSR

HIVEP1

1211

P15822
HTRGVPPLLKSFLQE

XRRA1

411

Q6P2D8
EQPSHPEGSRRAKLE

TMEM139

126

Q8IV31
PGPSGFHKQRRSLDT

WWC3

431

Q9ULE0
VFLDRKLGTQPSLPH

USP33

121

Q8TEY7
RQTPRHAAPGKDTDR

TRIO

2511

O75962
PGSHVRQKAVRRPSS

TRIM3

441

O75382
KGTFVLRDLPLQHSP

KCNC4

606

Q03721