Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesstrabecula morphogenesis

THBS3 HEG1 FBN2

3.41e-0557233GO:0061383
GeneOntologyBiologicalProcessbone trabecula formation

THBS3 FBN2

1.07e-0414232GO:0060346
GeneOntologyBiologicalProcessendothelial cell morphogenesis

HEG1 PLOD3

1.24e-0415232GO:0001886
GeneOntologyBiologicalProcessbone trabecula morphogenesis

THBS3 FBN2

1.80e-0418232GO:0061430
GeneOntologyCellularComponentextracellular matrix

ADAM10 THBS3 PLOD3 OC90 FBN2

6.30e-04656235GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

ADAM10 THBS3 PLOD3 OC90 FBN2

6.39e-04658235GO:0030312
DomainEGF_2

MEGF11 THBS3 HEG1 FBN2 EPHA3

1.51e-05265235PS01186
DomainEGF_CA

THBS3 HEG1 FBN2

1.56e-0486233PF07645
DomainEGF_3

MEGF11 THBS3 HEG1 FBN2

1.79e-04235234PS50026
DomainEGF

MEGF11 THBS3 HEG1 FBN2

1.79e-04235234SM00181
DomainEGF_Ca-bd_CS

THBS3 HEG1 FBN2

2.23e-0497233IPR018097
DomainEGF-like_dom

MEGF11 THBS3 HEG1 FBN2

2.24e-04249234IPR000742
DomainEGF_CA

THBS3 HEG1 FBN2

2.37e-0499233PS01187
DomainEGF_1

MEGF11 THBS3 HEG1 FBN2

2.45e-04255234PS00022
DomainEGF-like_CS

MEGF11 THBS3 HEG1 FBN2

2.68e-04261234IPR013032
DomainEGF_CA

THBS3 HEG1 FBN2

4.38e-04122233SM00179
DomainEGF-like_Ca-bd_dom

THBS3 HEG1 FBN2

4.59e-04124233IPR001881
DomainhEGF

MEGF11 FBN2

5.38e-0428232PF12661
DomainGrowth_fac_rcpt_

THBS3 FBN2 EPHA3

8.95e-04156233IPR009030
DomainASX_HYDROXYL

HEG1 FBN2

6.67e-03100232PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

HEG1 FBN2

7.47e-03106232IPR000152
Domain-

ZNF548 ZNF264 ZNF565 ZNF148

8.84e-036792343.30.160.60
DomainKRAB

ZNF548 ZNF264 ZNF565

9.31e-03358233PS50805
DomainKRAB

ZNF548 ZNF264 ZNF565

9.31e-03358233PF01352
Domainzf-C2H2

ZNF548 ZNF264 ZNF565 ZNF148

9.48e-03693234PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF548 ZNF264 ZNF565 ZNF148

9.53e-03694234IPR013087
DomainKRAB

ZNF548 ZNF264 ZNF565

1.01e-02369233SM00349
DomainKRAB

ZNF548 ZNF264 ZNF565

1.02e-02370233IPR001909
DomainZINC_FINGER_C2H2_2

ZNF548 ZNF264 ZNF565 ZNF148

1.39e-02775234PS50157
DomainZINC_FINGER_C2H2_1

ZNF548 ZNF264 ZNF565 ZNF148

1.40e-02777234PS00028
DomainZnf_C2H2-like

ZNF548 ZNF264 ZNF565 ZNF148

1.52e-02796234IPR015880
DomainZnf_C2H2

ZNF548 ZNF264 ZNF565 ZNF148

1.58e-02805234IPR007087
DomainZnF_C2H2

ZNF548 ZNF264 ZNF565 ZNF148

1.60e-02808234SM00355
Pubmed

EphrinA/EphA-induced ectodomain shedding of neural cell adhesion molecule regulates growth cone repulsion through ADAM10 metalloprotease.

ADAM10 EPHA3

1.25e-06323224117969
Pubmed

Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.

ADAM10 EPHA3

1.25e-06323216239146
Pubmed

Optimizing Genomic Methods for Mapping and Identification of Candidate Variants in ENU Mutagenesis Screens Using Inbred Mice.

PLOD3 FBN2

4.18e-06523229208648
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ADAM10 BST2 THBS3 HEG1 PLOD3 PLXND1 FBN2

8.68e-06120123735696571
Pubmed

Subtype-Specific Genes that Characterize Subpopulations of Callosal Projection Neurons in Mouse Identify Molecularly Homologous Populations in Macaque Cortex.

PLXND1 EPHA3

3.79e-051423226874185
Pubmed

In the developing cerebral cortex: axonogenesis, synapse formation, and synaptic plasticity are regulated by SATB2 target genes.

PLXND1 EPHA3

4.37e-051523236028553
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

ADAM10 FBN2

1.35e-042623234189436
Pubmed

HIV-host interactome revealed directly from infected cells.

ADAM10 CCT7 THBS3

1.96e-0417223327375898
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

ADAM10 PLOD3 FBN2

2.06e-0417523328071719
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

CDC25A ZNF548 CCT7 PLOD3 FBN2

3.77e-0497423528675297
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

CCT7 PLOD3 FBN2

3.97e-0421923331353912
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SIK2 MLC1 DOP1B

4.30e-0422523312168954
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

CDC25A CCT7 TRPM2 DOP1B

5.03e-0457323428330616
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

ADAM10 CCT7 PLOD3 FBN2

6.48e-0461323422268729
CytobandEnsembl 112 genes in cytogenetic band chr3q21

HEG1 ZNF148

2.91e-03160232chr3q21
CytobandEnsembl 112 genes in cytogenetic band chr21q22

TRPM2 DOP1B

1.52e-02377232chr21q22
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF548 ZNF264 ZNF565

2.10e-021192233chr19q13
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF548 ZNF264 ZNF565 ZNF148

1.32e-0371813428
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM10 BST2

3.15e-02394132471
CoexpressionNABA_MATRISOME_PRIMARY_METASTATIC_COLORECTAL_TUMOR

ADAM10 PLOD3 PLXND1

1.86e-0559233M47989
CoexpressionGSE11057_CD4_CENT_MEM_VS_PBMC_DN

MLC1 PLXND1 FBN2 TRPM2

2.35e-05195234M3117
CoexpressionGSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN

SIK2 ADAM10 HEG1 PLXND1

2.55e-05199234M6519
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

ADAM10 CLIP1 HEG1 ZNF148 DOP1B

4.49e-05466235M13522
CoexpressionDAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP

ADAM10 HEG1 FBN2 EPHA3

7.01e-05258234M4680
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1 EPHA3

2.67e-0619223456b021c297a21dff357531f21e2464f85186106d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1 EPHA3

2.73e-06193234cc355b2ed6510619cad969ae074126d7c8db784d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1 EPHA3

2.90e-06196234a20a56d8997d6db2a10046c8801c619a379de83c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1 EPHA3

3.02e-06198234b027a141ab531d0f5d6a26811a53427e7b0771dd
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1 EPHA3

3.08e-06199234a3ec743b978ba8fdf1677b4971b5731f50ddd30f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1 EPHA3

3.08e-0619923433f1669eeb701986b4dec409efdb6c06c3c41c2b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1 EPHA3

3.14e-0620023493e13937ec74418a697c37d56f57509fb2154780
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BST2 PLXND1 FBN2

3.07e-05119233c3f1223356e7f245a460ea5568a223e34e458dc1
ToppCellP07-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MEGF11 THBS3 EPHA3

6.50e-051532335501095bcf73080872ae01128f21399f9cfc5dd1
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

PROK1 HEG1 EPHA3

6.62e-05154233511923b27469ea20f8bd82a9ec27119a6e884644
ToppCellControl-Myeloid-MoAM1,_IL1R2|Control / Condition, Lineage and Cell class

HEG1 FBN2 TRPM2

8.42e-05167233ab6029ba037b6a499da8758864c44e174cde5587
ToppCellControl-Myeloid-MoAM1,_IL1R2|Myeloid / Condition, Lineage and Cell class

HEG1 FBN2 TRPM2

8.42e-051672336e5140527437193f441ca96893b9a00d346614f3
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MLC1 FBN2 DOP1B

8.88e-05170233cf22a843ae2d9cd6693507fed2b7c6a45abea10e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HEG1 PLXND1 EPHA3

9.51e-051742333d4c05ea5719ca65e85d1f15198453034791087c
ToppCellControl-Myeloid-MoAM2,_CCL18|Control / Condition, Lineage and Cell class

THBS3 PLXND1 TRPM2

9.51e-051742334c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SIK2 CLIP1 TRPM2

9.84e-051762331510cdfcfb46ce1196a1220c07fb5f3986c81b78
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BST2 HEG1 PLXND1

9.84e-0517623396779273b94345250cf53ba671203345b43d9e00
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

THBS3 PLXND1 TRPM2

1.00e-04177233470f54fe2b21c7350ea471e02039461a3808f700
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.12e-04184233a12a6a481e78adc62da1904431f62b119f70b15f
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BST2 FHL5 HEG1

1.16e-04186233422d24e3e1a9397bb7d5c7ef75de2fd7ae8e136d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PROK1 HEG1 FBN2

1.16e-0418623396f6603cc75fa1ffc2a2fdb94ec0ec09498e540a
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BST2 FHL5 HEG1

1.16e-0418623365da0666a10a59f8cc379589860a2e98fe487754
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BST2 FHL5 HEG1

1.16e-04186233dc84fef1ca2f5d5d818b76a3321559e87d1c4a4d
ToppCellRV-07._Pericyte|World / Chamber and Cluster_Paper

FHL5 PLXND1 EPHA3

1.18e-04187233dc274d6bbda619a2c914d84e2b4069cfef1739d1
ToppCelllymphoid-NK_cell-TNFRSF18+IL7R+_NK_cell|lymphoid / Lineage, cell class and subclass

MLC1 BST2 PLXND1

1.18e-0418723399dfa50f6325b0d66d23ee8dcaa6437e7161628a
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BST2 HEG1 PLXND1

1.21e-04189233d17e8467699c7ca7694a313c26111f085df5204e
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BST2 HEG1 PLXND1

1.21e-04189233feedac2751ed770f80bc56fec31662b5b3826f58
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.23e-04190233bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HEG1 PLXND1 EPHA3

1.27e-04192233bacbaef1f230051335f4433e55db07a161b96b4c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HEG1 PLXND1 EPHA3

1.27e-0419223328eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.29e-041932336a623acd1adad9a78eddc32ffedb16352ad3fdfa
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HEG1 PLXND1 EPHA3

1.29e-041932332e72309607902dabe3218888b22a77fe941f3570
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.31e-04194233cf9cf115dbbb9997f7c303ae07f42f3d80ff9a21
ToppCellfacs-Kidney-nan-3m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BST2 HEG1 PLXND1

1.31e-041942335fa2dfca32cca4abfda0af90b83f2b2a826f9b6e
ToppCellfacs-Kidney-nan-3m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BST2 HEG1 PLXND1

1.31e-0419423304df35246287815bdd28adaf885bdb98cf49524e
ToppCellfacs-Kidney-nan-3m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BST2 HEG1 PLXND1

1.31e-0419423390928d6c96c6304ae35dcc0275f7889de93da100
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.31e-04194233fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HEG1 PLXND1 EPHA3

1.33e-041952336bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

BST2 HEG1 PLXND1

1.33e-04195233cc3d6f98d310e8840ff497d7258c5ccf54e6c624
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HEG1 PLXND1 EPHA3

1.33e-0419523377e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.35e-0419623365d882c6e7f6d5778b8a5fd4fdaf012e1b9f6100
ToppCellParenchymal-10x3prime_v2-Stromal-Mesofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

THBS3 FBN2 ZNF565

1.39e-041982330cd930e374c2c48d1991b51c025f9801b22ecee7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 EPHA3

1.39e-041982335e781583908c4ee107d986904a646a7c6b8e3591
ToppCell18-Airway-Endothelial-Endothelial|Airway / Age, Tissue, Lineage and Cell class

BST2 HEG1 PLXND1

1.39e-0419823370d3ea0837dd6ad62abdf349e566a2e62c8e345a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.39e-041982338e45551224fbb30c0658ad47dd98335ecf165437
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MLC1 FHL5 EPHA3

1.39e-04198233882710bd6215e299257dd3df234292db9a2823ba
ToppCell18-Airway-Endothelial|Airway / Age, Tissue, Lineage and Cell class

BST2 HEG1 PLXND1

1.39e-041982336b7f1b352dc3a803af87106ffb63944bd4286dfe
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.39e-04198233953630dbe3154b1b102b87de0feca2cbf124eabe
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.39e-04198233259fbcc0f2ac281a3e4d693de45b986fe5e24841
ToppCellParenchymal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

THBS3 FBN2 ZNF565

1.39e-04198233e0df6d6ff2a9c41d813f84a2a5ee7cb5f6fc3e30
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

BST2 HEG1 PLXND1

1.41e-0419923370e05d7c0c68c28754ce0e72434b205aed6287ae
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.41e-0419923314e09eaa2335d4503de50250eb4258dd5b85b304
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.41e-04199233e6715288a586631676722f2323f0d833431161cf
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.41e-04199233f35e9c05d0a0339ff691b38564da7aad8e9218aa
ToppCell3'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BST2 HEG1 PLXND1

1.41e-04199233f5c8ad751d21ea0b199a02846faecd04bf100033
ToppCellCOVID-19-kidney-Glomerular_EC|kidney / Disease (COVID-19 only), tissue and cell type

BST2 HEG1 PLXND1

1.41e-04199233fffd2f9042b55531dac4e5b463b5cee80402e7bb
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

BST2 HEG1 PLXND1

1.41e-04199233243b7c72f83c12a34d8ea300fca63b04216268a4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.44e-042002332e47888e041ec3d265425d1df97b6665c6da889c
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ADAM10 BST2 HEG1

1.44e-04200233bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.44e-042002333007583eaad3a5ae2df010513d3e4df59155123d
ToppCell3'-Adult-LargeIntestine-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BST2 HEG1 PLXND1

1.44e-0420023374a3b9ec8faa1d187ad8b0d12f5c89bde2d7248e
ToppCell3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BST2 HEG1 PLXND1

1.44e-04200233cee07d9370656e1c428a7a9e9fbd175129901374
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.44e-0420023350fa0f8a3e490d5941b34e66a10158eba6c909d4
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

ADAM10 BST2 HEG1

1.44e-04200233432384faeade8e609154fab3d96c955a8ec868dd
ToppCell3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BST2 HEG1 PLXND1

1.44e-04200233074b5766c61fa8e61d0b1b76688ea0d1ec401e5b
ToppCellTracheal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FHL5 PLXND1 EPHA3

1.44e-042002339d3ae9ea47b1017adb63aa02d10e98193d478458
ToppCellTracheal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FHL5 PLXND1 EPHA3

1.44e-0420023378cd0b7d221ef855512ee9ac9a291f61622c2e24
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.44e-04200233b1be27d134a8633e3e7862c6a0d7be2001d387f0
ToppCellkidney_cells-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.44e-042002339f1626a7e1bd00977a5c316cafbdf654b52bad94
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.44e-04200233ced14d83222dbebca85c40540e76824e683354f3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.44e-042002337a69ad5b6c84f1aebacea5cacb9bc5c63dfd1dac
ToppCell3'-Adult-LymphNode-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BST2 HEG1 PLXND1

1.44e-04200233663e2b4672f193844bb9bf4873749114977c19b3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1 PLXND1

1.44e-04200233dba96cda5f3b780a3d4171b61bc8aaddc1f5d466
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CDC25A MEGF11

6.08e-047123200ca08c442de977f909f1691c6fa40e7382d02dd
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CDC25A MEGF11

6.08e-0471232499262154a694d9f84358de9f5deff0d022c7632
ToppCellBronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF548 THBS3

1.61e-03116232b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCellASK440-Endothelial-Endothelium|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq

BST2 HEG1

1.78e-031222322f76ec3b527e9528fbb006599a96e8bbdf9e0e62
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Interneuron|GW10 / Sample Type, Dataset, Time_group, and Cell type.

BST2 EPHA3

1.89e-03126232ec445ec097c9c45cd47b8cfa8c140df5b298695e
ToppCellTCGA-Mesothelium|World / Sample_Type by Project: Shred V9

THBS3 HEG1

2.01e-031302323ef1733eb57e2a9a3298ce0d65401f19e2084df1
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)|Cerebellum / BrainAtlas - Mouse McCarroll V32

FHL5 EPHA3

2.14e-031342321fa13185a4dfb4563473184c0c4f449011d88631
ToppCellBronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FHL5 EPHA3

2.14e-03134232bffd6ce8998368d4f486b64c220eab3a44ba147b
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

FHL5 EPHA3

2.14e-031342321ab99a22d0d7657f62f8ea7d96bb24e88de54fd4
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Cerebellum / BrainAtlas - Mouse McCarroll V32

FHL5 EPHA3

2.14e-031342328a3acf32cabc37b49d6488d43cdaae7cec79d119
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-Neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

SIK2 EPHA3

2.20e-03136232b46450292e0cd549eb3bafdd3fed22f41d85bfbe
ToppCellRV-14._Fibroblast_III|RV / Chamber and Cluster_Paper

CDC25A EPHA3

2.33e-03140232b4fee8eb6bf855b364b00bda3f78e49d851bbca0
ToppCell10x5'-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

MEGF11 FBN2

2.36e-031412327671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCellSevere-B_intermediate-14|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CLIP1 ZNF565

2.40e-031422329c7d5783302974b883bd887f997d094eb5925ec2
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FHL5 EPHA3

2.46e-031442321c001a5a3bbe4ecbce8305f8b260e933033550dd
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THBS3 EPHA3

2.50e-03145232590ba937c741ae67460f303eca88b1cd3ac87f64
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|367C / Donor, Lineage, Cell class and subclass (all cells)

ZNF264 DOP1B

2.63e-0314923241f28138bde45d0b814e116837e5a32b5e80d54a
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEG1 PLXND1

2.81e-031542321e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MEGF11 THBS3

2.81e-03154232e94cd11488003347120eacd3ced0a8923ed09ccc
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HEG1 PLXND1

2.85e-0315523259035d792c26d870a8b097939e97fa47859ba68c
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SIK2 FHL5

2.92e-03157232c779a53b2c67d566f5d417e753cd17196a6bfd1c
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

THBS3 TRPM2

3.03e-031602328bb873704895c3b35bba8af78fedbabf7df42e71
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_endothelial_cell_-_unspecif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1

3.06e-031612322a721b6228045adb2dfbcd4990d371f961dc5dc2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1

3.10e-03162232c399b9e4854916a59f5cae2d8dbf19660f8759be
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BST2 HEG1

3.10e-03162232a291248b693c771845174393934a782f1d8bd7ce
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh|GI_large-bowel / Manually curated celltypes from each tissue

PLXND1 ZNF565

3.14e-031632324104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HEG1 PLXND1

3.14e-0316323273c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
DrugButoconazole nitrate [32872-77-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A

CDC25A SIK2 BST2 PLXND1

4.07e-051952345388_DN
DrugLomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; PC3; HT_HG-U133A

CDC25A ADAM10 MLC1 CLIP1

4.23e-051972343723_DN
DrugDihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; PC3; HT_HG-U133A

CDC25A THBS3 HEG1 PLOD3

4.32e-051982342081_UP
Drugtetraethylenepentamine pentahydrochloride; Down 200; 100uM; ssMCF7; HG-U133A

SIK2 CLIP1 THBS3 PLXND1

4.40e-05199234498_DN
DrugEthosuximide [77-67-8]; Up 200; 28.4uM; HL60; HG-U133A

CDC25A MLC1 CLIP1 HEG1

4.40e-051992341433_UP
DrugAmoxicillin [26787-78-0]; Up 200; 11uM; PC3; HT_HG-U133A

CDC25A MLC1 PLXND1 FBN2

4.40e-051992346285_UP
DiseaseBeta blocking agent use measurement

CDC25A SIK2 FBN2

9.40e-05114233EFO_0009929
DiseaseDiuretic use measurement

CDC25A SIK2 FBN2

3.00e-04169233EFO_0009928
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

PLOD3 FBN2

7.82e-0453232C4707243
Diseaseirritable bowel syndrome symptom measurement

TRPM2 DOP1B

9.36e-0458232EFO_0021536
Diseasecortical thickness

ADAM10 THBS3 PLXND1 FBN2 EPHA3

1.44e-031113235EFO_0004840
Diseasefunctional brain measurement

FHL5 EPHA3

1.86e-0382232EFO_0007849
DiseaseAgents acting on the renin-angiotensin system use measurement

CDC25A SIK2 FBN2

2.17e-03335233EFO_0009931
Diseasemean arterial pressure

FHL5 THBS3 FBN2

6.62e-03499233EFO_0006340
DiseaseCalcium channel blocker use measurement

THBS3 FBN2

1.19e-02213232EFO_0009930
Diseaseurate measurement, bone density

MLC1 CLIP1 MEGF11

1.19e-02619233EFO_0003923, EFO_0004531

Protein segments in the cluster

PeptideGeneStartEntry
YDYCRVPMEDGDKRC

BST2

6

Q10589
PCNDFRGYCDVFMRC

ADAM10

631

O14672
MDLCRQDPECEFYFS

PLOD3

376

O60568
YMGDRCQEECPFGSF

MEGF11

296

A6BM72
DYMTRCFEECFRPVK

DOP1B

446

Q9Y3R5
CMYSCLRETVGEPFF

PLXND1

1501

Q9Y4D7
DGYRLENETCMSCPF

HEG1

1221

Q9ULI3
PRDFEDYGCTCRFEM

OC90

91

Q02509
DYGCTCRFEMEGLPV

OC90

96

Q02509
CSRFPDGRYRCSMDL

PROK1

86

P58294
LCEEQFMSRDDYPFC

FHL5

196

Q5TD97
AGYEERGFMCQACRP

EPHA3

261

P29320
AYRCECEMGFTPASD

FBN2

1471

P35556
SRGEERPYCEICEMF

CLIP1

1411

P30622
CEFSSERGPRMCRYV

CDC25A

431

P30304
EGRFRIPYFMSEDCE

SIK2

231

Q9H0K1
QYFADRDMFCAGRVP

CCT7

301

Q99832
PYECRECGMAFIRSS

ZNF565

486

Q8N9K5
CEEMRQLFYDPDECG

TRPM2

841

O94759
NPCFRGVDCMEVYEY

THBS3

281

P49746
ERPYECMECGKAFNR

ZNF264

256

O43296
ERPYECRECGKFFMD

ZNF548

306

Q8NEK5
PFRCDECGMRFIQKY

ZNF148

226

Q9UQR1
FPAEMDYLRCAAGSC

MLC1

76

Q15049