Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
HumanPheno	Congenital, generalized hypertrichosis	ABCA5 KMT2A	6.47e-06	3	8	2	HP:0004540
Domain	PHD	KMT2A PHF3	2.88e-03	75	20	2	PF00628
Domain	Znf_PHD-finger	KMT2A PHF3	3.19e-03	79	20	2	IPR019787
Domain	PHD	KMT2A PHF3	4.03e-03	89	20	2	SM00249
Domain	Znf_PHD	KMT2A PHF3	4.21e-03	91	20	2	IPR001965
Domain	ZF_PHD_2	KMT2A PHF3	4.58e-03	95	20	2	PS50016
Domain	ZF_PHD_1	KMT2A PHF3	4.68e-03	96	20	2	PS01359
Domain	Ion_trans_dom	KCNH3 TRPM5	6.53e-03	114	20	2	IPR005821
Domain	Ion_trans	KCNH3 TRPM5	6.53e-03	114	20	2	PF00520
Domain	AAA+_ATPase	ABCA5 MDN1	1.02e-02	144	20	2	IPR003593
Domain	AAA	ABCA5 MDN1	1.02e-02	144	20	2	SM00382
Domain	Znf_FYVE_PHD	KMT2A PHF3	1.07e-02	147	20	2	IPR011011
Domain	P-loop_NTPase	ABCA5 MYH7 DDX4 MDN1	1.14e-02	848	20	4	IPR027417
Domain	-	TOPORS KMT2A PHF3	1.16e-02	449	20	3	3.30.40.10
Domain	Znf_RING/FYVE/PHD	TOPORS KMT2A PHF3	1.23e-02	459	20	3	IPR013083
Domain	LRR_8	CNOT6 LRCH4	1.42e-02	171	20	2	PF13855
Domain	Leu-rich_rpt_typical-subtyp	CNOT6 LRCH4	1.52e-02	177	20	2	IPR003591
Domain	LRR_TYP	CNOT6 LRCH4	1.52e-02	177	20	2	SM00369
Domain	LRR	CNOT6 LRCH4	1.93e-02	201	20	2	PS51450
Pubmed	Normal embryonic and germ cell development in mice lacking alpha 1,3-fucosyltransferase IX (Fut9) which show disappearance of stage-specific embryonic antigen 1.	DDX4 MDN1	3.47e-06	5	21	2	15121843
Pubmed	Cyclin D2 rescues size and function of GATA4 haplo-insufficient hearts.	TBX18 MYH7	1.90e-05	11	21	2	22923619
Pubmed	IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development.	TBX18 MYH7	2.70e-05	13	21	2	21429986
Pubmed	Myocardial overexpression of ANKRD1 causes sinus venosus defects and progressive diastolic dysfunction.	TBX18 MYH7	5.28e-05	18	21	2	31688894
Pubmed	Thymosin beta 4 is dispensable for murine cardiac development and function.	TBX18 MYH7	5.28e-05	18	21	2	22158707
Pubmed	Misexpression of Tbx18 in cardiac chambers of fetal mice interferes with chamber-specific developmental programs but does not induce a pacemaker-like gene signature.	TBX18 MYH7	5.28e-05	18	21	2	27180262
Pubmed	Prokineticin receptor-1 signaling promotes Epicardial to Mesenchymal Transition during heart development.	TBX18 MYH7	7.24e-05	21	21	2	27150455
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TOPORS KMT2A PHF3 NAF1 MDN1	8.16e-05	774	21	5	15302935
Pubmed	Tbx18 expression demarcates multipotent precursor populations in the developing urogenital system but is exclusively required within the ureteric mesenchymal lineage to suppress a renal stromal fate.	TBX18 DDX4	8.72e-05	23	21	2	23685333
Pubmed	APC controls asymmetric Wnt/β-catenin signaling and cardiomyocyte proliferation gradient in the heart.	TBX18 MYH7	1.12e-04	26	21	2	26493106
Pubmed	Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2.	TBX18 MYH7	1.30e-04	28	21	2	15901664
Pubmed	Crim1 has cell-autonomous and paracrine roles during embryonic heart development.	TBX18 MYH7	1.60e-04	31	21	2	26821812
Pubmed	Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.	TBX18 MYH7	1.93e-04	34	21	2	31024170
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	CNOT6 LRCH4 KMT2A PHF3 MYADM MDN1	1.96e-04	1497	21	6	31527615
Pubmed	Notch signaling regulates smooth muscle differentiation of epicardium-derived cells.	TBX18 MYH7	2.04e-04	35	21	2	21252157
Pubmed	Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse.	MYADM DDX4	3.38e-04	45	21	2	26902285
Pubmed	Age-associated alteration of gene expression patterns in mouse oocytes.	TOPORS DDX4	4.35e-04	51	21	2	15317747
Cytoband	Ensembl 112 genes in cytogenetic band chr7q22	LRCH4 RINT1	4.48e-03	219	21	2	chr7q22
GeneFamily	PHD finger proteins	KMT2A PHF3	2.14e-03	90	14	2	88
Disease	glycerol measurement	SIPA1L2 NPRL3	1.40e-04	26	20	2	EFO_0010115
Disease	aortic measurement	NPRL3 TBX18 MYH7	6.23e-04	251	20	3	EFO_0020865
Disease	QRS-T angle	KMT2A MYH7	2.33e-03	106	20	2	EFO_0020097
Disease	anthropometric measurement	NPRL3 TBX18	5.72e-03	168	20	2	EFO_0004302
Disease	attempted suicide	ABCA5 TBX18	6.40e-03	178	20	2	EFO_0004321

Protein segments in the cluster

Peptide	Gene	Start	Entry
KYGGRSIRKDPFFRN	ABCA5	1231	Q8WWZ7
PTRNRGFSKRGGYRD	DDX4	121	Q9NQI0
RDGRNFPFKNYRQAG	GVINP1	2346	Q7Z2Y8
NRDKDGFSNPGYRVR	ANKRD62	21	A6NC57
RKGFPNRILYGDFRQ	MYH7	706	P12883
GRRRYGRARSKGFNA	KCNH3	151	Q9ULD8
NRRLKHFPRGAARSY	LRCH4	51	O75427
YGGRKVLSRAFRNRF	MDN1	1201	Q9NU22
GSRGNKLLFRYPFQR	NPRL3	16	Q12980
YQFDEKYGGQPRRSR	MYADM	261	Q96S97
YPRRSARARSNMFFG	KMT2A	2616	Q03164
YFPTKNRQRRGCFRV	CERCAM	196	Q5T4B2
ERGYNGFFSPKSRAR	CNOT6	256	Q9ULM6
EGRRKFSFYGNLSPR	SIPA1L2	1466	Q9P2F8
GPEASRQRFRQFQYR	ZSCAN20	46	P17040
RQRFRQFQYRDAAGP	ZSCAN20	51	P17040
FYQDGRPGDRRRAEK	TRPM5	481	Q9NZQ8
TPLQKRFRYHFRGNR	RINT1	311	Q6NUQ1
RNPFAKGFRDSGRNR	TBX18	321	O95935
RPFNRGKGDRQRFYS	PHF3	1911	Q92576
GRYRDISAEFFRRNP	TOPORS	276	Q9NS56
KGYRNREFTRGFSRA	NAF1	366	Q96HR8