Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabnormal aortic sinus morphology

THSD4 FBN1

1.31e-052512MP:0010482
DomainPHD

KMT2C BAZ2B TRIM28 PHF21A

7.52e-0575564PF00628
DomainZnf_PHD-finger

KMT2C BAZ2B TRIM28 PHF21A

9.21e-0579564IPR019787
DomainPHD

KMT2C BAZ2B TRIM28 PHF21A

1.46e-0489564SM00249
DomainZnf_PHD

KMT2C BAZ2B TRIM28 PHF21A

1.60e-0491564IPR001965
DomainZF_PHD_2

KMT2C BAZ2B TRIM28 PHF21A

1.88e-0495564PS50016
DomainZF_PHD_1

KMT2C BAZ2B TRIM28 PHF21A

1.96e-0496564PS01359
DomainRING

KMT2C TRIM28 NEURL1 SCAF11 CBLB PHF21A

2.95e-04305566SM00184
Domain-

KMT2C BAZ2B TRIM28 NEURL1 SCAF11 CBLB PHF21A

3.71e-044495673.30.40.10
DomainZnf_RING

KMT2C TRIM28 NEURL1 SCAF11 CBLB PHF21A

4.21e-04326566IPR001841
DomainZnf_RING/FYVE/PHD

KMT2C BAZ2B TRIM28 NEURL1 SCAF11 CBLB PHF21A

4.24e-04459567IPR013083
DomainTIL

FCGBP MUC19

5.72e-0412562PF01826
DomainC8

FCGBP MUC19

5.72e-0412562PF08742
DomainUnchr_dom_Cys-rich

FCGBP MUC19

6.74e-0413562IPR014853
DomainC8

FCGBP MUC19

6.74e-0413562SM00832
DomainTIL_dom

FCGBP MUC19

7.85e-0414562IPR002919
DomainZnf_FYVE_PHD

KMT2C BAZ2B TRIM28 PHF21A

9.85e-04147564IPR011011
DomainVWD

FCGBP MUC19

1.03e-0316562SM00216
DomainVWF_type-D

FCGBP MUC19

1.03e-0316562IPR001846
DomainVWFD

FCGBP MUC19

1.03e-0316562PS51233
DomainAT_hook

KMT2C PHF21A

1.03e-0316562PF02178
DomainVWD

FCGBP MUC19

1.03e-0316562PF00094
DomainVWC_out

FCGBP MUC19

1.46e-0319562SM00215
DomainZF_RING_2

KMT2C TRIM28 NEURL1 SCAF11 CBLB

1.96e-03298565PS50089
DomainAT_hook

KMT2C PHF21A

2.95e-0327562SM00384
DomainAT_hook_DNA-bd_motif

KMT2C PHF21A

2.95e-0327562IPR017956
DomainHMGI/Y_DNA-bd_CS

KMT2C PHF21A

3.88e-0331562IPR000637
DomainAnk_2

ANKRD11 DGKI BCOR NOTCH3

3.93e-03215564PF12796
Domain-

MYCL SREBF1 MESP2

4.28e-031095634.10.280.10
DomainSH2

TNS4 CBLB SH2B2

4.39e-03110563SM00252
DomainSH2

TNS4 CBLB SH2B2

4.50e-03111563PS50001
DomainHLH

MYCL SREBF1 MESP2

4.50e-03111563PF00010
DomainSH2

TNS4 CBLB SH2B2

4.62e-03112563IPR000980
Domain-

TNS4 CBLB SH2B2

4.62e-031125633.30.505.10
DomainAnk

ANKRD11 DGKI BCOR NOTCH3

4.84e-03228564PF00023
DomainHLH

MYCL SREBF1 MESP2

5.09e-03116563SM00353
DomainBHLH

MYCL SREBF1 MESP2

5.22e-03117563PS50888
DomainbHLH_dom

MYCL SREBF1 MESP2

5.34e-03118563IPR011598
DomainBROMODOMAIN_1

BAZ2B TRIM28

5.50e-0337562PS00633
DomainVWC

FCGBP MUC19

5.79e-0338562SM00214
Domain-

ANKRD11 DGKI BCOR NOTCH3

6.49e-032485641.25.40.20
DomainBROMODOMAIN_2

BAZ2B TRIM28

6.72e-0341562PS50014
DomainANK

ANKRD11 DGKI BCOR NOTCH3

6.77e-03251564SM00248
DomainANK_REPEAT

ANKRD11 DGKI BCOR NOTCH3

6.96e-03253564PS50088
DomainBROMO

BAZ2B TRIM28

7.04e-0342562SM00297
DomainBromodomain

BAZ2B TRIM28

7.04e-0342562IPR001487
Domain-

BAZ2B TRIM28

7.04e-03425621.20.920.10
DomainVWF_dom

FCGBP MUC19

7.04e-0342562IPR001007
DomainAnkyrin_rpt-contain_dom

ANKRD11 DGKI BCOR NOTCH3

7.05e-03254564IPR020683
DomainANK_REP_REGION

ANKRD11 DGKI BCOR NOTCH3

7.05e-03254564PS50297
DomainAnkyrin_rpt

ANKRD11 DGKI BCOR NOTCH3

7.85e-03262564IPR002110
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ANKRD13D MYCL TBC1D16 KMT2C AATK MAP1S TRIM28 SREBF1 ANKRD11 IRS2 ALKBH6 SH2B2 BAP1

2.10e-081105571335748872
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

MYCL KMT2C TRIM28 SREBF1 E2F2 TACC2 MAML3 PHF21A IKZF4 THAP7

2.12e-07709571022988430
Pubmed

Engrailed 1 coordinates cytoskeletal reorganization to induce myofibroblast differentiation.

FBN1 EN1

2.64e-06257234259830
Pubmed

Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome.

FBN1 NOTCH3

2.64e-06257232616814
Pubmed

ADAMTSL6β protein rescues fibrillin-1 microfibril disorder in a Marfan syndrome mouse model through the promotion of fibrillin-1 assembly.

THSD4 FBN1

2.64e-06257221880733
Pubmed

ADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formation.

THSD4 FBN1

2.64e-06257219940141
Pubmed

Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice.

SREBF1 IRS2

7.91e-06357210949029
Pubmed

Novel BCOR-MAML3 and ZC3H7B-BCOR Gene Fusions in Undifferentiated Small Blue Round Cell Sarcomas.

BCOR MAML3

7.91e-06357226752546
Pubmed

Increased insulin receptor substrate 2 expression is associated with steatohepatitis and altered lipid metabolism in obese subjects.

SREBF1 IRS2

1.58e-05457223147115
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

ANKRD13D THSD4 IRS2 SH2B2 NOTCH3

2.72e-0521457522199357
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SEC24C MAP1S TRIM28 BAG3 SCAF11 IRS2 BCOR BAP1

3.66e-0577457815302935
Pubmed

TAPP2 links phosphoinositide 3-kinase signaling to B-cell adhesion through interaction with the cytoskeletal protein utrophin: expression of a novel cell adhesion-promoting complex in B-cell leukemia.

RFTN1 SEC24C TRIM28

4.26e-054157319786618
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

MYCL TRIM28 SREBF1 E2F2 MESP2 PHF21A THAP7 NOBOX

4.96e-0580857820412781
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

FBN1 MUC19 BCOR PHF21A

5.09e-0512357426912792
Pubmed

Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration.

ADRA1A ABCA4

5.51e-05757227460988
Pubmed

The roles of Cbl-b and c-Cbl in insulin-stimulated glucose transport.

CBLB SH2B2

5.51e-05757212842890
Pubmed

Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome.

ACOD1 SREBF1

7.34e-05857232516576
Pubmed

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

MAML3 NOTCH3

9.43e-05957212370315
Pubmed

Nucleotide sequence, expression, and chromosomal mapping of Mrp and mapping of five related sequences.

MYCL MARCKS

1.18e-04105728406449
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

FLYWCH2 TRIM28 BAG3 TACC2 IRS2 BCOR MARCKS PHF21A

1.35e-0493457833916271
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

MYCL KMT2C TRIM28 E2F2 BCOR BAP1

1.58e-0449557627705803
Pubmed

TRIM28 functions as a negative regulator of aggresome formation.

TRIM28 BAG3

1.72e-041257233783327
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

KMT2C BAZ2B TRIM28 SREBF1 ANKRD11 SCAF11 BCOR PHF21A BAP1

2.39e-04129457930804502
Pubmed

Identification of oscillatory genes in somitogenesis from functional genomic analysis of a human mesenchymal stem cell model.

MESP2 MAML3

2.73e-041557217362910
Pubmed

Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth.

EN1 NOTCH3

2.73e-041557212167404
Pubmed

Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line.

MYCL TRIM28 MARCKS

3.02e-047957314729942
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

SEC24C MAP1S FLYWCH2 TRIM28 BAG3 SCAF11 TACC2 IRS2 MARCKS

4.60e-04141557928515276
Pubmed

The Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program.

MESP2 MAML3

4.92e-042057221750544
Pubmed

Correct timing of proliferation and differentiation is necessary for normal inner ear development and auditory hair cell viability.

MYCL E2F2

4.92e-042057223193000
Pubmed

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.

KMT2C BAP1

4.92e-042057229785026
Pubmed

Stress-induced NEDDylation promotes cytosolic protein aggregation through HDAC6 in a p62-dependent manner.

ANKRD13D BAG3

4.92e-042057233665565
Pubmed

High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization.

MYCL KMT2C NOTCH3

5.03e-049457316325481
Pubmed

Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.

MYCL SREBF1 MESP2

5.68e-049857318557763
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

MAP1S BAG3 BCOR MARCKS

5.78e-0423257425515538
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

BAG3 IRS2 BCOR PHF21A BAP1

6.14e-0441857534709266
Pubmed

A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development.

SREBF1 E2F2 PHF21A

6.39e-0410257319741146
Pubmed

A census of human transcription factors: function, expression and evolution.

MYCL SREBF1 E2F2 MESP2 EN1 THAP7 NOBOX

6.86e-0490857719274049
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

KMT2C MAP1S TRIM28 SCAF11

7.75e-0425157431076518
Pubmed

The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organs.

NEURL1 MAML3

8.36e-042657224391519
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

FBN1 NOTCH3

8.36e-042657234189436
Pubmed

Isolation and characterization of proteins associated with histone H3 tails in vivo.

KMT2C TRIM28

1.11e-033057217403666
Pubmed

TBX1 is required for normal stria vascularis and semicircular canal development.

FBN1 NOTCH3

1.19e-033157231550482
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

TRIM28 MAML3 NOTCH3

1.26e-0312957323022380
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

KMT2C MAP1S ANKRD11 IRS2 USP9Y

1.33e-0349757536774506
Pubmed

Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin.

OTUD1 BAP1

1.35e-033357230323974
Pubmed

Tandem immunoprecipitation of phosphotyrosine-mass spectrometry (TIPY-MS) indicates C19ORF19 becomes tyrosine-phosphorylated and associated with activated epidermal growth factor receptor.

IRS2 CBLB

1.35e-033357218271526
Cytoband12q12

MUC19 SCAF11

1.58e-034757212q12
CytobandEnsembl 112 genes in cytogenetic band chr12q12

MUC19 SCAF11

2.82e-0363572chr12q12
GeneFamilyPHD finger proteins

KMT2C BAZ2B TRIM28 PHF21A

4.57e-059040488
GeneFamilyAnkyrin repeat domain containing

ANKRD13D ANKRD11 DGKI BCOR NOTCH3

1.85e-04242405403
GeneFamilyBasic helix-loop-helix proteins

MYCL SREBF1 MESP2

1.84e-03110403420
GeneFamilyRing finger proteins

TRIM28 NEURL1 SCAF11 CBLB

3.11e-0327540458
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BSND TBC1D16 MELTF ABCA4 FCGBP

3.92e-061855756da9a06e1514d5d5f47359a14637f02539846096
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BSND TBC1D16 MELTF ABCA4 FCGBP

3.92e-061855754a188e2566a75d1b4f3c879a8c241c277c4b451c
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KMT2C BAZ2B MUC19 IRS2 MARCKS

4.02e-0618657523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellMonocytes-Tissue-resident_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

MYCL B3GNT6 FCGBP IRS2 MARCKS

4.46e-0619057507215e8f292cb54c670037aaf28393cddbe5548c
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THSD4 KMT2C ANKRD11 DGKI MAML3

4.82e-06193575779276e775cb2492e8dd36436295a536084a6415
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MELTF ABCA4 FCGBP PALM3

3.58e-051455748da10bc6611976e1ec85e09f04a2dc5bf6555c9e
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-5|TCGA-Colorectal / Sample_Type by Project: Shred V9

B3GNT6 ABCA4 FCGBP NEURL1

4.88e-051575745fb41af247465aa29aa7b8edd26e3d3794766f80
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ACOD1 NEURL1 SREBF1 DGKI

5.25e-051605741e210e526ea4d84fc58a798a26c0929bcb69fd89
ToppCellNS-critical-d_16-33-Epithelial-Ionocyte|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BSND NEURL1 MUC19 DGKI

6.35e-051685746a233045638cb83dab64789b996b7598c325001e
ToppCellBL-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BSND NEURL1 MUC19 DGKI

6.65e-05170574b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOD1 ARHGEF33 FCGBP TNS4

7.11e-051735747c5e4809205ce1a0a301c15442af00a2e2b9b301
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D16 FBN1 NOTCH3 IKZF4

7.11e-05173574a37f38478473290fe35aea8684befc3bf95b161f
ToppCellMild/Remission-B_naive-8|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

BAZ2B IRS2 CBLB MAML3

7.11e-05173574694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BSND MELTF ABCA4 FCGBP

7.27e-0517457446bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCellIIH-CD8-antiviral_CD4|IIH / Condition, Cell_class and T cell subcluster

KANSL1L SEC24C BAG3 CBLB

7.77e-05177574fe73608c40701eca88b260aeb5c0640d7bee72ba
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1-Excitatory_Neuron.Slc17a7.FIbcd1-Inhba_(CA1_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

B3GNT6 NPBWR1 NOBOX

7.96e-05655735fc678ea0490cbcfe00d569727b97ccba3a19232
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Prlr_(Entorhinal_cortex?)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

B3GNT6 NPBWR1 USP9Y

7.96e-056557357d0d892dab8bc8465067feeff279c967a43b781
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Prlr_(Entorhinal_cortex?)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

B3GNT6 NPBWR1 USP9Y

7.96e-0565573aba26f607f35c2920cdf956309285ad9e7b758a7
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-BEST2+_Goblet_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GNT6 FCGBP PALM3 TNS4

8.12e-05179574c833ded1f9e87be2ba2037820d92a389560b711c
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D16 FBN1 GGN NOTCH3

8.66e-05182574be9c312a44868d4ee266a64d066feb8c5bce5687
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D16 FBN1 GGN NOTCH3

8.66e-0518257474dbb706bcaa0f8c922bf3b0424bce5bb27167fa
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC19 DGKI MARCKS PHF21A

9.03e-051845747ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCell(0)_MSCs|World / Cell class and subclass of bone marrow stroma cells in homeostatis

RFTN1 FBN1 MARCKS NOTCH3

9.41e-05186574a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell(0)_MSCs-(00)_Lepr-MSC|World / Cell class and subclass of bone marrow stroma cells in homeostatis

RFTN1 FBN1 MARCKS NOTCH3

9.41e-05186574f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCellBAL-Control-Myeloid-MoAM-MoAM5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MELTF FCGBP MARCKS CAPN15

9.61e-0518757459d28f4ee1d463ae20abb8d7e7399b504d80698a
ToppCellControl-Myeloid-MoAM5|Control / Disease group,lineage and cell class （2021.01.30）

MELTF FCGBP MARCKS CAPN15

9.61e-051875748769341be67382cea2a590d962f4def7c39de883
ToppCellBAL-Control-Myeloid-MoAM-MoAM5-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MELTF FCGBP MARCKS CAPN15

9.61e-0518757425adf648c05c21534b4913254e73d43fc5f64e06
ToppCellBAL-Control-Myeloid-MoAM-MoAM5|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MELTF FCGBP MARCKS CAPN15

9.61e-051875743b0cfa9e5ea5e7d6dda689c328b9b5110b43ee1d
ToppCellBAL-Control-Myeloid-MoAM-MoAM5-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MELTF FCGBP MARCKS CAPN15

9.61e-051875740d589de12108230ced5b60229564f4a181e2f172
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD4 MELTF AATK NOTCH3

9.81e-05188574340f0e3e65c7a00d82d26621ff37107458bebc41
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD4 MELTF AATK NOTCH3

9.81e-051885749d384c0934f1461bc37b1f83e0877d7bee2116ee
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 RFTN1 FCGBP NOTCH3

1.00e-0418957427e5d706f10a6221f314faf642eede15deab3165
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 ADRA1A FBN1 NOTCH3

1.02e-0419057470c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 MELTF ACAA1 NEURL1

1.04e-04191574116fba9badea093e11f370996247cca0e4c02e8f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADRA1A FBN1 CBLB NOTCH3

1.04e-0419157404c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MESP2 TNS4 MARCKS NOTCH3

1.06e-041925745d24bb6c6c17a6b803b241d065b31896a7d86c37
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MESP2 TNS4 MARCKS NOTCH3

1.06e-04192574c6795ceba90f1a5d441dff92a737b9c7d28b06b0
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-suprabasal_differentiating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCL BAZ2B ANKRD11 MARCKS

1.09e-0419357449f4fbec91acda4727703e0e359ed780eefb8a22
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 RFTN1 FCGBP NOTCH3

1.09e-041935741526f51b589a7dc7a28f35f0e788dc38d338d2bc
ToppCell390C-Myeloid-Monocyte-CD14+_Monocyte|390C / Donor, Lineage, Cell class and subclass (all cells)

ACOD1 MELTF OTUD1 MARCKS

1.09e-04193574a50ee6110ea272d9d9f41d48bb5d43711cc00a32
ToppCellfacs-Thymus-nan-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANSL1L KMT2C TRIM28 MARCKS

1.11e-04194574f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GNT6 ABCA4 FCGBP NEURL1

1.11e-0419457449cc5f5de4380302100e8cd937f08abe317ac75e
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GNT6 ABCA4 FCGBP NEURL1

1.11e-04194574fb935df966c451e659b8bde281f8aebcb632f6cf
ToppCellfacs-Thymus-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANSL1L KMT2C TRIM28 MARCKS

1.11e-04194574cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCellfacs-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANSL1L KMT2C TRIM28 MARCKS

1.11e-0419457466c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GNT6 ABCA4 FCGBP NEURL1

1.13e-04195574c5f33b420c9ac14dc67fea632b8c2bc2442cbf3d
ToppCellMild/Remission-B_naive-8|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

BAZ2B IRS2 CBLB MAML3

1.13e-041955740a3221e4d1fa31a35868bdda0f0cc873c233b407
ToppCellfacs-Thymus-nan-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANSL1L TRIM28 E2F2 MARCKS

1.13e-0419557479114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 RFTN1 FBN1 NOTCH3

1.13e-04195574edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-Goblet_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GNT6 ABCA4 FCGBP NEURL1

1.13e-04195574219c5d0cde7f6082755154f54db221413ec555cb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RFTN1 ADRA1A FBN1 NOTCH3

1.15e-04196574b8759e6231e0254797d6c30930407b79440c57bb
ToppCell(2)_5-FU-(3)_LEPR+_perivascular_cells|(2)_5-FU / Stress and Cell class

RFTN1 FBN1 MARCKS NOTCH3

1.15e-04196574cc0a172de71d9a1a882c9e78652dae70e007d012
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 RFTN1 FBN1 NOTCH3

1.15e-04196574fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 RFTN1 FBN1 NOTCH3

1.15e-04196574802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

BSND NEURL1 DGKI MAML3

1.17e-04197574ff4df77117165b6b25315e29b0722cc136eba607
ToppCellBAL-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MYCL RFTN1 FCGBP MARCKS

1.17e-04197574513ada82bbbb6a624d89edaa54f8c4a303dfb5e7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BSND MELTF ABCA4 FCGBP

1.17e-041975745a71e859ebe734fc70a056807b07d99fa867c687
ToppCellBAL-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYCL RFTN1 FCGBP MARCKS

1.17e-041975746f83fc049f38f3de6bc5180ad4b51ceb4d5dcdb6
ToppCellControl-Myeloid-cDC|Control / Disease group,lineage and cell class （2021.01.30）

MYCL RFTN1 FCGBP MARCKS

1.17e-04197574aef933107da42a763b35041c90950db07707c0cb
ToppCellBAL-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MYCL RFTN1 FCGBP MARCKS

1.17e-0419757415e683f4a610aad3e06723747c8e56ca25f57414
ToppCellBAL-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYCL RFTN1 FCGBP MARCKS

1.17e-041975746ac50c02899531a25885749d5305da788dfa9dbc
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BSND MAP1S NEURL1 DGKI

1.20e-04198574dd0465b45b02cb8edf0914d19afb52fcaaeb012c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 RFTN1 FBN1 CBLB

1.20e-04198574a860246bcea847249a78fd2e86ed8e04371060db
ToppCelldroplet-Trachea|droplet / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 MELTF FBN1 BAG3

1.22e-041995741c7d30765ddb2291967da5d15664c6238c680c1d
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD4 FBN1 BAZ2B MARCKS

1.22e-0419957408bdcabc3fce787578a8eb66fc8412b0974fa6cc
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD4 FBN1 BAZ2B MARCKS

1.22e-04199574da016849b804fbf80edbfa8f8f56c9df8bbf2d51
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 KMT2C BAZ2B MAML3

1.22e-0419957494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD4 FBN1 BAZ2B MARCKS

1.22e-041995743cf62666ffd000427fdbb7cf940793f98c3ed29c
ToppCelldroplet-Trachea|droplet / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD4 MELTF FBN1 BAG3

1.22e-04199574b9038a1ccf3ef3123e2e39afbe6213c363437443
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

THSD4 FBN1 BAZ2B TACC2

1.24e-0420057408bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD4 FBN1 BAZ2B MARCKS

1.24e-04200574ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P2-Tnr|Thalamus / BrainAtlas - Mouse McCarroll V32

MYCL FCGBP EN1

1.89e-04875730c3a3ed1f279ed29a0113cc73ae590157a4b7334
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)-|Thalamus / BrainAtlas - Mouse McCarroll V32

MYCL FCGBP EN1

1.89e-04875735d1dbbd86d82cbce4f2a3365242eb92d9c821a9e
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P2|Thalamus / BrainAtlas - Mouse McCarroll V32

MYCL FCGBP EN1

1.89e-0487573a93dbe73b337cc2d93208822728b9badf30b6870
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)|Thalamus / BrainAtlas - Mouse McCarroll V32

MYCL FCGBP EN1

1.89e-048757345ef27ba84f731e4b2188813cd6931950e5164ac
DrugSecurinine [5610-40-2]; Up 200; 18.4uM; HL60; HT_HG-U133A

TBC1D16 KANSL1L AATK BAG3 EN1 NOTCH3 IKZF4

4.52e-071895772729_UP
DiseaseAdenoid Cystic Carcinoma

KMT2C BCOR EN1 MAML3 MARCKS

1.12e-06100545C0010606
Diseasestomach carcinoma (is_implicated_in)

BCOR CBLB

2.14e-0412542DOID:5517 (is_implicated_in)
Diseasevisual epilepsy (biomarker_via_orthology)

BAG3 NEURL1 MARCKS

6.08e-0490543DOID:11832 (biomarker_via_orthology)
Diseasehypertrophic cardiomyopathy

KMT2C BAG3 PHF21A

6.48e-0492543EFO_0000538
DiseaseIntrahepatic Cholangiocarcinoma

KMT2C BAP1

8.84e-0424542C0345905
Diseasestomach carcinoma (is_marker_for)

KMT2C CBLB

8.84e-0424542DOID:5517 (is_marker_for)
DiseaseExtrahepatic Cholangiocarcinoma

KMT2C BAP1

8.84e-0424542C3805278
DiseaseStreptozotocin Diabetes

ADRA1A SREBF1 IRS2

1.03e-03108543C0038433
DiseaseDiabetes Mellitus, Experimental

ADRA1A SREBF1 IRS2

1.03e-03108543C0011853
DiseaseAlloxan Diabetes

ADRA1A SREBF1 IRS2

1.03e-03108543C0002152
DiseaseCholangiocarcinoma

KMT2C BAP1

1.04e-0326542C0206698
Diseasethoracic aortic aneurysm

RFTN1 FBN1

1.38e-0330542EFO_0004282
DiseaseHyperglycemia, Postprandial

FBN1 IRS2

1.38e-0330542C1855520
DiseaseHyperglycemia

FBN1 IRS2

1.38e-0330542C0020456
Diseasespontaneous coronary artery dissection

THSD4 FBN1

1.48e-0331542EFO_0010820
DiseaseFEV/FEC ratio

MYCL THSD4 FBN1 FCGBP BAG3 NEURL1 ANKRD11 IKZF4

1.67e-031228548EFO_0004713

Protein segments in the cluster

PeptideGeneStartEntry
ALDAASSPPNAAACP

ALKBH6

191

Q3KRA9
APSSAVAASGNPFPC

ANKRD13D

441

Q6ZTN6
ASLCAPDGPAPNTVA

ANKRD11

2266

Q6UB99
DSNVCSPGAPAAHPE

ABCA4

1316

P78363
PGSAPAALCSESQSP

BAZ2B

701

Q9UIF8
GNASDSSNCTQPPAP

ADRA1A

6

P35348
CANAGQDASPTAGPE

ARHGEF33

471

A8MVX0
AAGSCAQAPSHSPPN

BAP1

316

Q92560
QPSGACANADSAPPA

AHI1-DT

101

P0C7V0
RPASASPAPNANADG

BCOR

566

Q6W2J9
CSAPAGRNQSPEPSS

RFTN1

211

Q14699
KDNPAAPGPASSQCS

NOBOX

371

O60393
AAGDSSEANGPCPSP

PALM3

176

A6NDB9
EAAQPSPSAGCRGAP

CAPN15

261

O75808
AAPASAAAGPPGASC

OTUD1

86

Q5VV17
SSSQQCAAASPPGLP

KANSL1L

876

A0AUZ9
CAAASPPGLPSENQD

KANSL1L

881

A0AUZ9
GNAVACPVSSAQSPP

KMT2C

3746

Q8NEZ4
ASPPSAACGSPASQL

MAP1S

591

Q66K74
PAAPNPASSPANCAV

MAML3

401

Q96JK9
GSPSACPGAQAAPER

MESP2

221

Q0VG99
PPEAAGENFAPCSVA

FLYWCH2

121

Q96CP2
QLPSCSDGSQAPARP

CBLB

891

Q13191
GPSNPATCSNVAPFQ

MUC19

731

Q7Z5P9
PPGASNASCAAAPCL

NOTCH3

1331

Q9UM47
GAISNGPDCTPPANA

PHF21A

641

Q96BD5
GCSGPPSAPASQARA

GGN

321

Q86UU5
AASLLCAPDANCGPP

EN1

166

Q05925
GDAPPAAAPAASCSA

IRS2

151

Q9Y4H2
ACPQGPAPLASFQDD

BSND

186

Q8WZ55
QTAPPAAAPGTCLDA

E2F2

51

Q14209
AAAAAASPPGPCSGA

DGKI

26

O75912
PACPTSCNGAAAPSN

FCGBP

756

Q9Y6R7
AFGEPCQPCPAQNSA

FBN1

691

P35555
AAACEAPSAAGPGAP

MARCKS

276

P29966
PSPPEVASNSPACNN

ACOD1

461

A6NK06
PGPPCVANASANATA

B3GNT6

66

Q6ZMB0
CGQVAAAAAAQPPAS

BAG3

151

O95817
SGAPPASTAQAPCGQ

SEC24C

66

P53992
CDAPGNSNPSLSVPS

SCAF11

346

Q99590
PLTDPGASPSNGCQD

IKZF4

441

Q9H2S9
PANASGPDPALSCSN

NPBWR1

11

P48145
PQAAPCLSGAPQASA

ACAA1

21

P09110
SQQCSGAAAPAPGAP

MELTF

706

P08582
ACSLPSGAGNNSEPP

TCP11X2

176

Q5H9J9
DCAGCAPSPPATADQ

AATK

546

Q6ZMQ8
CVTQPNPSPGSADGD

SREBF1

816

P36956
PLGAQADEAGCSAQP

THAP7

181

Q9BT49
SAAPDCTPSLEAGNP

MYCL

126

P12524
APAAGCPIPQNSLNS

NEURL1

266

O76050
GAASPSNPCPATRSN

TNS4

401

Q8IZW8
DGAQPASQPACSPSG

TBC1D16

171

Q8TBP0
AAAACPPASPSDAAG

SH2B2

551

O14492
CLASPAAAPEDGPQT

TACC2

121

O95359
ASGNTGEAPPCQPDS

TACC2

1036

O95359
SPFASPGPSSQACDN

USP9Y

2136

O00507
ADPDCSNGQPQAAPT

YJU2

271

Q9BW85
NNRPAEATPCDNGPC

THSD4

836

Q6ZMP0
CLGPAAPAAANSSGD

TRIM28

91

Q13263
SGSCEDGQSAPAQPP

UNQ6190/PRO20217

96

Q6UXQ8