Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	olfactory nerve formation	PLXNA3 PLXNA1	1.41e-05	2	78	2	GO:0021628
GeneOntologyBiologicalProcess	olfactory nerve morphogenesis	PLXNA3 PLXNA1	4.23e-05	3	78	2	GO:0021627
GeneOntologyCellularComponent	USH2 complex	ADGRV1 USH2A	8.64e-05	4	80	2	GO:1990696
GeneOntologyCellularComponent	leading edge membrane	KCNC2 ITGA8 FGD5 ADGRV1 USH2A ITGB3	1.55e-04	210	80	6	GO:0031256
GeneOntologyCellularComponent	stereocilia ankle link	ADGRV1 USH2A	2.15e-04	6	80	2	GO:0002141
GeneOntologyCellularComponent	stereocilia ankle link complex	ADGRV1 USH2A	2.15e-04	6	80	2	GO:0002142
GeneOntologyCellularComponent	stereocilium membrane	ADGRV1 USH2A	2.15e-04	6	80	2	GO:0060171
GeneOntologyCellularComponent	periciliary membrane compartment	ADGRV1 USH2A	2.15e-04	6	80	2	GO:1990075
GeneOntologyCellularComponent	neuron projection membrane	KCNC2 ITGA8 ADGRV1 USH2A	2.77e-04	82	80	4	GO:0032589
GeneOntologyCellularComponent	stereocilia coupling link	ADGRV1 USH2A	3.99e-04	8	80	2	GO:0002139
GeneOntologyCellularComponent	semaphorin receptor complex	PLXNA3 PLXNA1	1.10e-03	13	80	2	GO:0002116
GeneOntologyCellularComponent	synaptic membrane	GPM6A NEO1 KCNC2 ITGA8 GSG1L AKAP1 ITGB3 HTT	1.74e-03	583	80	8	GO:0097060
HumanPheno	Cupped ear	DNAJC21 HUWE1 ECE1 PLXNA1 ZMYM3	3.04e-05	69	28	5	HP:0000378
Domain	TIL	MUC2 SSPOP OTOG	1.62e-05	12	80	3	PF01826
Domain	C8	MUC2 SSPOP OTOG	1.62e-05	12	80	3	PF08742
Domain	Unchr_dom_Cys-rich	MUC2 SSPOP OTOG	2.10e-05	13	80	3	IPR014853
Domain	C8	MUC2 SSPOP OTOG	2.10e-05	13	80	3	SM00832
Domain	TIL_dom	MUC2 SSPOP OTOG	2.66e-05	14	80	3	IPR002919
Domain	VWD	MUC2 SSPOP OTOG	4.07e-05	16	80	3	SM00216
Domain	VWF_type-D	MUC2 SSPOP OTOG	4.07e-05	16	80	3	IPR001846
Domain	VWFD	MUC2 SSPOP OTOG	4.07e-05	16	80	3	PS51233
Domain	VWD	MUC2 SSPOP OTOG	4.07e-05	16	80	3	PF00094
Domain	VWC_out	MUC2 SSPOP OTOG	6.98e-05	19	80	3	SM00215
Domain	Cys_knot_C	MUC2 SSPOP OTOG	1.63e-04	25	80	3	IPR006207
Domain	CTCK_2	MUC2 SSPOP OTOG	1.63e-04	25	80	3	PS01225
Domain	-	CD84 IL10RB PLXNA3 CD2 NEO1 OBSCN LY9 USH2A ANKFN1 PLXNA1	5.21e-04	663	80	10	2.60.40.10
Domain	Plexin_cytopl	PLXNA3 PLXNA1	6.40e-04	9	80	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA3 PLXNA1	6.40e-04	9	80	2	IPR013548
Domain	Plexin	PLXNA3 PLXNA1	6.40e-04	9	80	2	IPR031148
Domain	VWF_dom	MUC2 SSPOP OTOG	7.70e-04	42	80	3	IPR001007
Domain	Ig-like_fold	CD84 IL10RB PLXNA3 CD2 NEO1 OBSCN LY9 USH2A ANKFN1 PLXNA1	8.45e-04	706	80	10	IPR013783
Domain	PSI	PLXNA3 ITGB3 PLXNA1	8.83e-04	44	80	3	IPR016201
Domain	PSI	PLXNA3 ITGB3 PLXNA1	1.01e-03	46	80	3	SM00423
Domain	FN3	IL10RB NEO1 OBSCN USH2A ANKFN1	1.19e-03	185	80	5	SM00060
Domain	FN3	IL10RB NEO1 OBSCN USH2A ANKFN1	1.64e-03	199	80	5	PS50853
Domain	FN3_dom	IL10RB NEO1 OBSCN USH2A ANKFN1	2.04e-03	209	80	5	IPR003961
Domain	UBA-like	USP28 N4BP2 HUWE1	2.61e-03	64	80	3	IPR009060
Domain	CTCK_1	MUC2 SSPOP	2.65e-03	18	80	2	PS01185
Domain	USP_CS	USP18 USP28 USP9Y	2.85e-03	66	80	3	IPR018200
Domain	USP_1	USP18 USP28 USP9Y	3.37e-03	70	80	3	PS00972
Domain	UCH	USP18 USP28 USP9Y	3.51e-03	71	80	3	PF00443
Domain	USP_2	USP18 USP28 USP9Y	3.51e-03	71	80	3	PS00973
Domain	USP_3	USP18 USP28 USP9Y	3.65e-03	72	80	3	PS50235
Domain	USP_dom	USP18 USP28 USP9Y	3.65e-03	72	80	3	IPR028889
Domain	Peptidase_C19_UCH	USP18 USP28 USP9Y	3.65e-03	72	80	3	IPR001394
Domain	Znf_C2H2_jaz	DNAJC21 ZMAT4	3.96e-03	22	80	2	IPR022755
Domain	zf-C2H2_jaz	DNAJC21 ZMAT4	3.96e-03	22	80	2	PF12171
Domain	CT	MUC2 OTOG	3.96e-03	22	80	2	SM00041
Domain	UIM	USP28 HUWE1	4.70e-03	24	80	2	PS50330
Domain	Integrin_dom	ITGA8 ITGB3	5.10e-03	25	80	2	IPR032695
Domain	UIM_dom	USP28 HUWE1	5.10e-03	25	80	2	IPR003903
Domain	fn3	NEO1 OBSCN USH2A ANKFN1	5.17e-03	162	80	4	PF00041
Domain	IPT	PLXNA3 PLXNA1	5.93e-03	27	80	2	SM00429
Domain	ARM-like	HUWE1 CTNND2 USP9Y MN1 HTT	6.06e-03	270	80	5	IPR011989
Domain	ZnF_U1	DNAJC21 ZMAT4	6.82e-03	29	80	2	SM00451
Domain	Znf_U1	DNAJC21 ZMAT4	6.82e-03	29	80	2	IPR003604
Domain	TIG	PLXNA3 PLXNA1	7.77e-03	31	80	2	PF01833
Domain	Sema	PLXNA3 PLXNA1	7.77e-03	31	80	2	SM00630
Domain	Semap_dom	PLXNA3 PLXNA1	7.77e-03	31	80	2	IPR001627
Domain	Sema	PLXNA3 PLXNA1	7.77e-03	31	80	2	PF01403
Domain	SEMA	PLXNA3 PLXNA1	7.77e-03	31	80	2	PS51004
Domain	-	EYS ADGRV1 USH2A	7.89e-03	95	80	3	2.60.120.200
Domain	PSI	PLXNA3 PLXNA1	8.27e-03	32	80	2	PF01437
Domain	IPT	PLXNA3 PLXNA1	8.27e-03	32	80	2	IPR002909
Domain	Plexin_repeat	PLXNA3 PLXNA1	8.27e-03	32	80	2	IPR002165
Pubmed	Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus.	CD84 CD2 LY9	6.76e-07	8	81	3	15589166
Pubmed	Characteristics of Retinitis Pigmentosa Associated with ADGRV1 and Comparison with USH2A in Patients from a Multicentric Usher Syndrome Study Treatrush.	ADGRV1 USH2A	5.36e-06	2	81	2	34638692
Pubmed	Molecular cloning, characterization, and chromosomal localization of the mouse homologue of CD84, a member of the CD2 family of cell surface molecules.	CD84 LY9	5.36e-06	2	81	2	10079287
Pubmed	Usher's Syndrome Type II: A Comparative Study of Genetic Mutations and Vestibular System Evaluation.	ADGRV1 USH2A	5.36e-06	2	81	2	28653555
Pubmed	Disease expression in Usher syndrome caused by VLGR1 gene mutation (USH2C) and comparison with USH2A phenotype.	ADGRV1 USH2A	5.36e-06	2	81	2	15671307
Pubmed	Identification of plexin family molecules in mice.	PLXNA3 PLXNA1	1.60e-05	3	81	2	8806646
Pubmed	PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome.	ADGRV1 USH2A	1.60e-05	3	81	2	20440071
Pubmed	Differential expression of plexin-A subfamily members in the mouse nervous system.	PLXNA3 PLXNA1	1.60e-05	3	81	2	11241833
Pubmed	The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chains.	IL10RB IL26	1.60e-05	3	81	2	15178681
Pubmed	Targeted next generation sequencing in Italian patients with Usher syndrome: phenotype-genotype correlations.	ADGRV1 USH2A	1.60e-05	3	81	2	29142287
Pubmed	Tm4sf19 deficiency inhibits osteoclast multinucleation and prevents bone loss.	ITGB3 TM4SF19	1.60e-05	3	81	2	38016540
Pubmed	Myeloid translocation gene 16b is a dual A-kinase anchoring protein that interacts selectively with plexins in a phospho-regulated manner.	PLXNA3 PLXNA1	1.60e-05	3	81	2	20138877
Pubmed	The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1.	ADGRV1 USH2A	1.60e-05	3	81	2	16434480
Pubmed	Non-USH2A mutations in USH2 patients.	ADGRV1 USH2A	1.60e-05	3	81	2	22147658
Pubmed	Adenylyl cyclase 6 plays a minor role in the mouse inner ear and retina.	ADGRV1 USH2A	3.20e-05	4	81	2	37127773
Pubmed	Individual USH2 proteins make distinct contributions to the ankle link complex during development of the mouse cochlear stereociliary bundle.	ADGRV1 USH2A	3.20e-05	4	81	2	26401052
Pubmed	Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism.	ADGRV1 USH2A	3.20e-05	4	81	2	18463160
Pubmed	Synaptotagmin gene content of the sequenced genomes.	SYT14 SYT14P1	3.20e-05	4	81	2	15238157
Pubmed	Ablation of whirlin long isoform disrupts the USH2 protein complex and causes vision and hearing loss.	ADGRV1 USH2A	3.20e-05	4	81	2	20502675
Pubmed	Deafness-Associated ADGRV1 Mutation Impairs USH2A Stability through Improper Phosphorylation of WHRN and WDSUB1 Recruitment.	ADGRV1 USH2A	3.20e-05	4	81	2	37066759
Pubmed	Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.	PLXNA3 PLXNA1	3.20e-05	4	81	2	11306810
Pubmed	Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling.	CD84 ITGB3	3.20e-05	4	81	2	16037392
Pubmed	PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.	PLXNA3 PLXNA1	3.20e-05	4	81	2	25518740
Pubmed	Usher Syndrome Type II	ADGRV1 USH2A	3.20e-05	4	81	2	20301515
Pubmed	Localization of PDZD7 to the stereocilia ankle-link associates this scaffolding protein with the Usher syndrome protein network.	ADGRV1 USH2A	3.20e-05	4	81	2	23055499
Pubmed	Determination of cell adhesion sites of neuropilin-1.	PLXNA3 PLXNA1	3.20e-05	4	81	2	10725340
Pubmed	Whirlin and PDZ domain-containing 7 (PDZD7) proteins are both required to form the quaternary protein complex associated with Usher syndrome type 2.	ADGRV1 USH2A	3.20e-05	4	81	2	25406310
Pubmed	Susceptibility loci for the defective foreign protein-induced tolerance in New Zealand Black mice: implication of epistatic effects of Fcgr2b and Slam family genes.	CD84 LY9	3.20e-05	4	81	2	21604261
Pubmed	A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.	PLXNA3 PLXNA1	3.20e-05	4	81	2	8570614
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CYRIA FRY PLK2 WAPL USP28 GLS SENP6 CHD6 POGZ HUWE1 CTNND2 USP9Y	4.13e-05	1285	81	12	35914814
Pubmed	A novel Usher protein network at the periciliary reloading point between molecular transport machineries in vertebrate photoreceptor cells.	ADGRV1 USH2A	5.33e-05	5	81	2	17906286
Pubmed	Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.	PLXNA3 PLXNA1	5.33e-05	5	81	2	25313870
Pubmed	Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice.	ADGRV1 USH2A	5.33e-05	5	81	2	24334608
Pubmed	Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2.	ADGRV1 USH2A	5.33e-05	5	81	2	16301216
Pubmed	Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP.	CD84 LY9	5.33e-05	5	81	2	11389028
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	N4BP2 GLS CHD6 POGZ HUWE1 AKAP1 ZMYM3	5.58e-05	418	81	7	34709266
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	WWC2 WAPL SLC41A3 SENP6 POGZ HUWE1 AKAP1 MN1 ZMYM3	7.99e-05	774	81	9	15302935
Pubmed	Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patients.	CD84 LY9	7.99e-05	6	81	2	11477068
Pubmed	Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells.	CD84 LY9	7.99e-05	6	81	2	11689425
Pubmed	Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages.	PLXNA3 PLXNA1	7.99e-05	6	81	2	19480842
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	GPM6A FRY EYS USH2A ITGB3	1.05e-04	199	81	5	23382691
Pubmed	Biochemical characterization of native Usher protein complexes from a vesicular subfraction of tracheal epithelial cells.	ADGRV1 USH2A	1.12e-04	7	81	2	20058854
Pubmed	Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.	PLXNA3 PLXNA1	1.12e-04	7	81	2	19063725
Pubmed	Whirlin replacement restores the formation of the USH2 protein complex in whirlin knockout photoreceptors.	ADGRV1 USH2A	1.12e-04	7	81	2	21212183
Pubmed	Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.	PLXNA3 PLXNA1	1.12e-04	7	81	2	19655386
Pubmed	Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.	PLXNA3 PLXNA1	1.12e-04	7	81	2	10520994
Pubmed	Expression profiles and pathway analysis in HEK 293 T cells overexpressing HIV-1 Tat and nucleocapsid using cDNA microarray.	CD2 CLPS ITGB3	1.13e-04	40	81	3	18051367
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	CD84 CD2 DIPK1A SYT14 OBSCN POGZ LY9 ECE1 CHML USH2A	1.40e-04	1031	81	10	16710414
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	PLXNA3 NEO1 OBSCN SELENOI ECE1	1.48e-04	214	81	5	22199357
Pubmed	The expression of plexins during mouse embryogenesis.	PLXNA3 PLXNA1	1.49e-04	8	81	2	15661641
Pubmed	The cell surface expression of SAP-binding receptor CD229 is regulated via its interaction with clathrin-associated adaptor complex 2 (AP-2).	CD84 LY9	1.49e-04	8	81	2	12621057
Pubmed	Microarray-based mutation analysis of 183 Spanish families with Usher syndrome.	ADGRV1 USH2A	1.49e-04	8	81	2	19683999
Pubmed	Integration of opposing semaphorin guidance cues in cortical axons.	PLXNA3 PLXNA1	1.49e-04	8	81	2	22368082
Pubmed	Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.	EYS LYPD2 SELENOI TASOR2	1.83e-04	120	81	4	21697133
Pubmed	PlexinA2 and semaphorin signaling during cardiac neural crest development.	PLXNA3 PLXNA1	1.91e-04	9	81	2	11688557
Pubmed	Physical and genetic linkage of the genes encoding Ly-9 and CD48 on mouse and human chromosomes 1.	CD84 LY9	1.91e-04	9	81	2	7797269
Pubmed	The role of neuropilins in cell signalling.	PLXNA3 PLXNA1	1.91e-04	9	81	2	19909241
Pubmed	Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.	PLXNA3 PLXNA1	2.38e-04	10	81	2	18804103
Pubmed	Massively parallel DNA sequencing facilitates diagnosis of patients with Usher syndrome type 1.	ADGRV1 USH2A	2.38e-04	10	81	2	24618850
Pubmed	Usher protein functions in hair cells and photoreceptors.	ADGRV1 USH2A	2.38e-04	10	81	2	24239741
Pubmed	Identification of chromosome intervals from 129 and C57BL/6 mouse strains linked to the development of systemic lupus erythematosus.	CD84 LY9	2.38e-04	10	81	2	16943797
Pubmed	Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures.	ARPP21 GSG1L HTT	2.62e-04	53	81	3	36265442
Pubmed	Semaphorin-5B Controls Spiral Ganglion Neuron Branch Refinement during Development.	PLXNA3 PLXNA1	2.91e-04	11	81	2	31209173
Pubmed	Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.	PLXNA3 PLXNA1	3.48e-04	12	81	2	25839327
Pubmed	PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.	PLXNA3 PLXNA1	3.48e-04	12	81	2	31690636
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	PLXNA3 PLXNA1	3.48e-04	12	81	2	24179230
Pubmed	Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.	PLXNA3 PLXNA1	3.48e-04	12	81	2	23991118
Pubmed	Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.	PLXNA3 PLXNA1	3.48e-04	12	81	2	28407732
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXNA3 PLXNA1	3.48e-04	12	81	2	21270798
Pubmed	Insulin receptor substrate-4 interacts with ubiquitin-specific protease 18 to activate the Jak/STAT signaling pathway.	USP18 HUWE1	4.11e-04	13	81	2	29285303
Pubmed	Functional assembly of accessory optic system circuitry critical for compensatory eye movements.	PLXNA3 PLXNA1	4.11e-04	13	81	2	25959730
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXNA3 PLXNA1	4.11e-04	13	81	2	10520995
Pubmed	Plexin signaling via off-track and rho family GTPases.	PLXNA3 PLXNA1	4.11e-04	13	81	2	11604131
Pubmed	Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.	PLXNA3 PLXNA1	4.11e-04	13	81	2	22723296
Pubmed	Venous endothelin modulates responsiveness of cardiac sympathetic axons to arterial semaphorin.	PLXNA3 ECE1	4.79e-04	14	81	2	30735130
Pubmed	A midline switch of receptor processing regulates commissural axon guidance in vertebrates.	PLXNA3 PLXNA1	4.79e-04	14	81	2	20159958
Pubmed	Sall1 balances self-renewal and differentiation of renal progenitor cells.	ITGA8 ZMAT4 VEGFD	5.24e-04	67	81	3	24550112
Pubmed	Impact of lactobacilli on orally acquired listeriosis.	GPM6A USP18 CLPS VEGFD	5.71e-04	162	81	4	23012479
Pubmed	Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.	ADGRV1 USH2A	6.29e-04	16	81	2	17567809
Pubmed	Integrin requirement for hippocampal synaptic plasticity and spatial memory.	ITGA8 ITGB3	6.29e-04	16	81	2	12904471
Pubmed	Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.	PLXNA3 PLXNA1	6.29e-04	16	81	2	17356169
Pubmed	Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.	PLXNA3 PLXNA1	6.29e-04	16	81	2	18489001
Pubmed	Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.	PLXNA3 PLXNA1	7.12e-04	17	81	2	11683995
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	PLXNA3 PLXNA1	7.12e-04	17	81	2	17626059
Pubmed	Isolation of a unique hepatic stellate cell population expressing integrin α8 from embryonic mouse livers.	GPM6A ITGA8	8.93e-04	19	81	2	29665133
Pubmed	Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.	FBXW12 HUWE1 FBXL5	1.05e-03	85	81	3	19028597
Pubmed	Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.	PLXNA3 PLXNA1	1.09e-03	21	81	2	21835343
Pubmed	Comparative physical and transcript maps of approximately 1 Mb around loop-tail, a gene for severe neural tube defects on distal mouse chromosome 1 and human chromosome 1q22-q23.	CD84 LY9	1.20e-03	22	81	2	11401431
Pubmed	Physical mapping of the mouse tilted locus identifies an association between human deafness loci DFNA6/14 and vestibular system development.	HTT FBXL5	1.31e-03	23	81	2	11597144
Pubmed	Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.	ITGA8 ITGB3	1.31e-03	23	81	2	23152823
Pubmed	A semaphorin code defines subpopulations of spinal motor neurons during mouse development.	PLXNA3 PLXNA1	1.43e-03	24	81	2	15869472
Pubmed	A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.	PLXNA3 PLXNA1	1.43e-03	24	81	2	28893946
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	WAPL USP28 SENP6 POGZ ADGRV1 GPATCH2L	1.49e-03	529	81	6	14621295
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	NEO1 WAPL N4BP2 SLC43A1 CHD6 HUWE1 AKAP1	1.62e-03	733	81	7	34672954
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FRY OBSCN UNC93A CHD6 HUWE1 CHML SSPOP	1.66e-03	736	81	7	29676528
Pubmed	Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter.	GPM6A ADGRV1	1.81e-03	27	81	2	34709416
Pubmed	Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.	ITGA8 ITGB3	1.81e-03	27	81	2	31541017
Pubmed	Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.	USP18 CYRIA POGZ ADGRV1 PABIR2 PLXNA1 FBXL5	1.84e-03	750	81	7	11230166
Pubmed	Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.	PLXNA3 PLXNA1	1.95e-03	28	81	2	18617019
Pubmed	Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8.	HUWE1 HTT	1.95e-03	28	81	2	25752541
Interaction	EDDM3A interactions	PLXNA3 ITGA8 ADGRV1 ECE1	1.18e-05	37	77	4	int:EDDM3A
Interaction	ST8SIA4 interactions	PLXNA3 DIPK1A ITGA8 ADGRV1 PLXNA1	1.74e-05	84	77	5	int:ST8SIA4
GeneFamily	Fibronectin type III domain containing\|USH2 complex	ADGRV1 USH2A	5.84e-05	4	57	2	1244
GeneFamily	Plexins	PLXNA3 PLXNA1	3.47e-04	9	57	2	683
GeneFamily	Ubiquitin specific peptidases	USP18 USP28 USP9Y	7.31e-04	56	57	3	366
GeneFamily	Fibronectin type III domain containing	NEO1 OBSCN USH2A ANKFN1	1.62e-03	160	57	4	555
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	EYS GSG1L CTNND2 USH2A ANKFN1 CDH12	4.62e-07	159	81	6	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EYS ZMAT4 GSG1L CTNND2 ANKFN1 CDH12	6.16e-07	167	81	6	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CD2 EYS LY9 ANKFN1 SSPOP IL26	1.19e-06	187	81	6	f31d865ce2a21bdf64dbe29ee3e4505ab482604a
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CYRIA TRAF3 DIPK1A ITGA8 LY9 IL26	1.71e-06	199	81	6	1bb02f41f3cc76a28581e38b0ca4c36b930b85b4
ToppCell	COVID-19-kidney-Mito-rich_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GPM6A KRT78 ITGA8 FGD5 OTOG	6.83e-06	145	81	5	afed661aef990edb8e7012ab67ace56443520c9f
ToppCell	COVID-19-kidney-Technical/muscle\|kidney / Disease (COVID-19 only), tissue and cell type	EYS ZMAT4 CTNND2 ANKFN1 CDH12	7.54e-06	148	81	5	0dbd87078f54ee1c2f8ec64e8bac9dfddb9c181e
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EYS KCNC2 GSG1L USH2A CDH12	7.54e-06	148	81	5	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EYS KCNC2 GSG1L USH2A CDH12	8.05e-06	150	81	5	0205318a870e091add66ee4305747dda9f51510d
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A41 OBSCN CTNND2 CHML TM4SF19	9.14e-06	154	81	5	1e32969bee810adaf2d560f0824a16227df513d8
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UNC93A ADGRV1 USP9Y USH2A CDH12	1.17e-05	162	81	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	EYS GSG1L CTNND2 USH2A CDH12	1.20e-05	163	81	5	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	COVID-19-Heart-T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EYS ARPP21 ZMAT4 GSG1L CDH12	1.52e-05	171	81	5	b2e753e811a7639956994609f73efcdb62d04f82
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRAF3 DIPK1A ITGA8 LY9 IL26	1.99e-05	181	81	5	6cdee2f56bc633b387b4dbbd78c624edbd712c24
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRAF3 DIPK1A ITGA8 LY9 IL26	1.99e-05	181	81	5	b75b8b025257bccfe661fd0f92ab284b2a9c12ee
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRAF3 DIPK1A ITGA8 LY9 IL26	1.99e-05	181	81	5	5a4fe0eca7cbc9cbc8a2fdbe795a7c5f4052a659
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A KCNC2 CLPS FGD5 ECE1	1.99e-05	181	81	5	2e15c46e8260bb04d8264478c19a707221996026
ToppCell	COVID-19-kidney-Mito-rich_EC\|kidney / Disease (COVID-19 only), tissue and cell type	GPM6A PLK2 ITGA8 FGD5 MN1	2.10e-05	183	81	5	3c4153479fc4ab2d073d92cee120480015555914
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN ADGRV1 USH2A SSPOP OTOG	2.16e-05	184	81	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN ADGRV1 USH2A SSPOP OTOG	2.16e-05	184	81	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN ADGRV1 USH2A SSPOP OTOG	2.16e-05	184	81	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RB USP18 PLK2 FGD5 ECE1	2.33e-05	187	81	5	3e25c15fa29f8c738044914e8b3420d5713f18d9
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RB USP18 PLK2 FGD5 ECE1	2.33e-05	187	81	5	965584ee44669a72866a20ddf7f657bc5a7f7a8b
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RB USP18 PLK2 FGD5 ECE1	2.33e-05	187	81	5	a7ef179e6561e17cafae10e1843bf82ac3ae0c89
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	EXOC6 EYS LYPD2 FGD5 ECE1	2.39e-05	188	81	5	366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	N4BP2 ADGRV1 HUWE1 CHML TASOR2	2.71e-05	193	81	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPM6A KCNE4 ITGA8 ZMAT4 FGD5	2.78e-05	194	81	5	e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FRY ITGA8 FGD5 ECE1 VEGFD	2.85e-05	195	81	5	4658fb197657d7692ee344ae76b11b0210c418ba
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPM6A CD2 EYS LY9 IL26	2.85e-05	195	81	5	69201b1172bcf0999c726516e4d30863afceab0b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPM6A FRY KCNC2 GLS ZMAT4	3.07e-05	198	81	5	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPM6A FRY GLS ZMAT4 CDH12	3.07e-05	198	81	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	mLN-B_cell-B_cell_IgA_Plasma\|B_cell / Region, Cell class and subclass	CD2 ITGA8 CTNND2 SSPOP IL26	3.14e-05	199	81	5	09494953bc7fff63cf2763ea89fca7abb97c186f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Cortical_neuron\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	GPM6A CYRIA PLK2 NEO1 ARPP21	3.22e-05	200	81	5	458fb0f40c1720f1cacedf78c40bd059692bfc62
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital\|World / Primary Cells by Cluster	GPM6A CYRIA NEO1 ARPP21 CDH12	3.22e-05	200	81	5	6bbe8e1f3e91678f1bfb14945365c1578a59a604
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital-19\|World / Primary Cells by Cluster	GPM6A CYRIA NEO1 ARPP21 CDH12	3.22e-05	200	81	5	c831d9e0a7178e3634da45548f91fa9e8dc6557c
ToppCell	COVID-19-kidney-Mito-rich_Int\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EYS UNC93A ZMAT4 CDH12	7.29e-05	122	81	4	a4220adb4e6055a599bd9bbf65d460fc4e68b543
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	EYS CTNND2 USH2A CDH12	1.21e-04	139	81	4	64c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD2 ZMAT4 SSPOP CDH12	1.24e-04	140	81	4	7ca49bd7ba9381e75c10f888775df17e5d46804d
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD2 ZMAT4 SSPOP CDH12	1.24e-04	140	81	4	1a31bc33d5723b9bc528cc0047ca5f4c80531c7a
ToppCell	COVID-19-Fibroblasts-Mesothelial_FB\|COVID-19 / group, cell type (main and fine annotations)	BNC1 OR9K2 USH2A CDH12	1.28e-04	141	81	4	7e6dcccb74e7ee90b69dc91b59491b84f3a713c9
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC93A ADGRV1 USP9Y USH2A	1.42e-04	145	81	4	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Mucinous_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	KCNC2 SYT14 MUC2 ANKFN1	1.42e-04	145	81	4	1e52e3c615b49e7388cd58a04e74cafac9552447
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Npnt_(Layer_5a)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SLC25A41 UNC93A USH2A	1.45e-04	56	81	3	112a412816287423089c0333a42432a6ab4500dc
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	EYS CTNND2 USH2A CDH12	1.46e-04	146	81	4	c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD84 CD2 LY9 IL26	1.62e-04	150	81	4	207fc230d7721149c7afc7970dd56817f52801d8
ToppCell	facs-Marrow-KLS-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARPP21 ZMAT4 ADGRV1 SSPOP	1.79e-04	154	81	4	37765512dfae557b9f6eb30a29463b93682a4404
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CYRIA SELENOI ITGB3 TM4SF19	1.88e-04	156	81	4	fc8b8aef29d6d1c0f0c1d08280d8aaff8d30535e
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	USP18 EYS TRAF3 GSG1L	1.93e-04	157	81	4	c779a53b2c67d566f5d417e753cd17196a6bfd1c
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KCNC2 DIPK1A ANKFN1 MRPL1	2.12e-04	161	81	4	2849fbc9611af208241b33da3cd18290aafe426b
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Cajal-Retzius\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	KCNC2 ZMAT4 FGD5 GSG1L	2.17e-04	162	81	4	1f589a763f3fd4e1e612809ef3903879d47dc1d8
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Cajal-Retzius\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	KCNC2 ZMAT4 FGD5 KRTAP10-2	2.22e-04	163	81	4	c1484e4de8b10e2f5fb14a7c02b2a015ffe0305e
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARPP21 KCNC2 UNC93A ZMAT4	2.33e-04	165	81	4	6d8b5669eee9b0903c9260fea707d186c9d7fefa
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARPP21 KCNC2 UNC93A ZMAT4	2.33e-04	165	81	4	02cd87dfa2ca40e13455a4b9308477e82f76289b
ToppCell	TCGA-Lung-Solid_Tissue_Normal\|TCGA-Lung / Sample_Type by Project: Shred V9	GPM6A WWC2 FGD5 VEGFD	2.38e-04	166	81	4	a8ebdd3cb7f59b3feeaacda45ce6d40d10db556f
ToppCell	TCGA-Lung-Solid_Tissue_Normal-Lung\|TCGA-Lung / Sample_Type by Project: Shred V9	GPM6A WWC2 FGD5 VEGFD	2.38e-04	166	81	4	c64971c27cb445dffc5a636d4b6a60261b93a2db
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	BNC1 GPM6A LYPD2 CDH12	2.38e-04	166	81	4	545f6c91102568791443717e522f89cb3bd1a070
ToppCell	TCGA-Lung-Solid_Tissue_Normal-Lung-Lung_normal_tissue\|TCGA-Lung / Sample_Type by Project: Shred V9	GPM6A WWC2 FGD5 VEGFD	2.38e-04	166	81	4	2f3072a7af048f184d33065fdd36153fd563155a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 OR52N2 FGD5 MN1	2.38e-04	166	81	4	8e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 FGD5 ECE1 MN1	2.38e-04	166	81	4	8e5f2afbeffae5e77fcb29e8fe9f5aa49779b619
ToppCell	TCGA-Lung-Solid_Tissue_Normal-Lung-Lung_normal_tissue-6\|TCGA-Lung / Sample_Type by Project: Shred V9	GPM6A WWC2 FGD5 VEGFD	2.38e-04	166	81	4	188f2575511f418216874aed9118aa6f165252cb
ToppCell	facs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A SLC10A1 USP28 ZMAT4	2.44e-04	167	81	4	961e722442d786ab15d1e490941d2be265a9057a
ToppCell	facs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A SLC10A1 USP28 ZMAT4	2.44e-04	167	81	4	3760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYRIA PLK2 DIPK1A ITGB3	2.49e-04	168	81	4	f45dbcd7753117a3e41e1412bce2100d52fa7fd0
ToppCell	367C-Fibroblasts-Fibroblast-G\|367C / Donor, Lineage, Cell class and subclass (all cells)	NEO1 ITGA8 VEGFD ITGB3	2.49e-04	168	81	4	8c95093b1ea45826f62893edd3c410fe53b563a4
ToppCell	367C-Fibroblasts-Fibroblast-G-\|367C / Donor, Lineage, Cell class and subclass (all cells)	NEO1 ITGA8 VEGFD ITGB3	2.49e-04	168	81	4	b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GPM6A WWC2 PLK2 ADGRV1	2.61e-04	170	81	4	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLK2 OBSCN ECE1 MUC2	2.61e-04	170	81	4	af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLK2 OBSCN ECE1 MUC2	2.73e-04	172	81	4	9a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCell	facs-GAT-Fat-24m-Epithelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT78 CLPS OBSCN ADGRV1	2.79e-04	173	81	4	815ba48a9222ea09ba8005e2d2f7c5addf118ad1
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	KCNC2 ZMAT4 CHML CDH12	2.79e-04	173	81	4	7e3897868dd3f6e4974f593c60649a543ffc8693
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC25A41 EYS CTNND2 CDH12	2.79e-04	173	81	4	9a3500b06d00d1d4ee42910a3a73327b21beab52
ToppCell	11.5-Distal-Mesenchymal-Mesenchyme_SERPINF1-high\|Distal / Age, Tissue, Lineage and Cell class	BNC1 GPM6A GSG1L MN1	2.79e-04	173	81	4	6989c9cebcd81eccceac7e5a86152676ee959386
ToppCell	AT1_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	GPM6A WWC2 GLS PLXNA1	2.79e-04	173	81	4	3afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCell	facs-GAT-Fat-24m-Epithelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT78 CLPS OBSCN ADGRV1	2.79e-04	173	81	4	98e464d9e6d6b69421e9e4041b638b6825247f60
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC10A1 SLC41A3 UNC93A ITGB3	2.79e-04	173	81	4	53e97835d7a518c278e7b90a0734eb0095d6aa33
ToppCell	droplet-Lung-LUNG-1m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC10A1 SLC41A3 UNC93A ITGB3	2.79e-04	173	81	4	889a880de5fc19d26b82cfef3067869a28ef17ca
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	EXOC6 LYPD2 FGD5 ECE1	2.79e-04	173	81	4	3a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCell	droplet-Heart-4Chambers-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A PLK2 FGD5 ECE1	2.79e-04	173	81	4	9a04271c51fae34f547db3206f9ff5857686e45c
ToppCell	facs-GAT-Fat-24m-Epithelial-epithelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT78 CLPS OBSCN ADGRV1	2.79e-04	173	81	4	3e6f0a08eddfd61871f7a85acccf6d539af6ebda
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CD84 EXOC6 SYT14 ITGB3	2.85e-04	174	81	4	a3f4981b10afa9d41a1c66c7f98522a8a534f82b
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A KCNC2 LYPD2 FGD5	2.85e-04	174	81	4	fa6eb451555766398996bbe8f555a3f4c0f3c108
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A KCNC2 LYPD2 FGD5	2.85e-04	174	81	4	1f5b0fa58b2a7335667357af7e50e5242cd13d7d
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CD84 EXOC6 SYT14 ITGB3	2.85e-04	174	81	4	6cc108dde4b3f98a78a6040280f0d5e4aaa5bd75
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CD84 EXOC6 SYT14 ITGB3	2.85e-04	174	81	4	4b8bc5568e36031c8ecf001bb646809038c23919
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A KCNC2 LYPD2 FGD5	2.85e-04	174	81	4	ac3aee6ed49d1c421f33509e3ffc5cb17750a473
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNE4 OBSCN VEGFD MN1	3.04e-04	177	81	4	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EXOC6 LYPD2 UNC93A FGD5	3.04e-04	177	81	4	5ff8dcfb030312126695d53a026d2e104a401b83
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EXOC6 FRY PLK2 ECE1	3.04e-04	177	81	4	16197068260fc062bf8b730a51a199887ea580b9
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	GPM6A WWC2 ADGRV1 CTNND2	3.17e-04	179	81	4	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	CD2 ITGA8 LY9 VEGFD	3.17e-04	179	81	4	e4224b2e9c4ae7da62cf670adf811f4112c7d060
ToppCell	T_cells-GZMK+_CD8+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	CD84 CD2 SLC10A1 LY9	3.17e-04	179	81	4	798f208014f2229c597934775646ddbbacf94b69
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR-_ILC3\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD84 CD2 EYS IL26	3.24e-04	180	81	4	3f0a692ad2823951e0ec23d0452f436c5f5c09c0
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GPM6A PLK2 ITGA8 FGD5	3.24e-04	180	81	4	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	CD2 DIPK1A SENP6 MRPL1	3.31e-04	181	81	4	b193f3606554adc55c5906219d114288bb1f978a
ToppCell	wk_08-11-Hematologic_Lymphocytic-T_&_ILC-ILC3\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CD2 EYS LY9 IL26	3.31e-04	181	81	4	bf2bd5ecec1e23a44f719d7efeb1f45d6c1c6b32
ToppCell	Mild-CD4+_T\|World / Disease group and Cell class	NEO1 FGD5 LY9 IL26	3.45e-04	183	81	4	c4ac8893d38a3da4e19fe2ef1756bd69c89e975c
ToppCell	COVID-19-lung-AT1\|lung / Disease (COVID-19 only), tissue and cell type	GPM6A WWC2 ADGRV1 CTNND2	3.45e-04	183	81	4	942530449e9c6583705eeb8f6f12621daea57252
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EXOC6 PLK2 LYPD2 FGD5	3.45e-04	183	81	4	c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCell	droplet-Mammary_Gland-nan-3m-Lymphocytic-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD84 CD2 DIPK1A SYT14	3.45e-04	183	81	4	3b8f2b1df10c3543c7581493b531fe3fa40fe7fc
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A KCNC2 LYPD2 ECE1	3.45e-04	183	81	4	b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCell	droplet-Trachea-nan-3m-Endothelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A PLK2 FGD5 ECE1	3.52e-04	184	81	4	fa5c3020e75fdde1363393dea97ebd99f1eae9ff
Disease	worry measurement	ARPP21 SYT14 ECE1 HTT	7.18e-04	154	77	4	EFO_0009589
Disease	perinatal necrotizing enterocolitis (biomarker_via_orthology)	IL10RB MUC2	8.91e-04	17	77	2	DOID:8677 (biomarker_via_orthology)
Disease	intellectual disability (implicated_via_orthology)	GPM6A ITGA8 POGZ	1.01e-03	75	77	3	DOID:1059 (implicated_via_orthology)
Disease	gut microbiome measurement, bone density	SENP6 GSG1L PLXNA1	1.13e-03	78	77	3	EFO_0003923, EFO_0007874
Disease	alcohol consumption measurement	CYRIA WAPL KCNC2 USP28 SYT14 SENP6 ADGRV1 CTNND2 TM4SF19 HTT	1.42e-03	1242	77	10	EFO_0007878
Disease	frailty measurement	SYT14 HTT	1.64e-03	23	77	2	EFO_0009885
Disease	hearing impairment	ADGRV1 USH2A MN1	2.17e-03	98	77	3	C1384666
Disease	retinitis pigmentosa (implicated_via_orthology)	EYS USH2A	2.26e-03	27	77	2	DOID:10584 (implicated_via_orthology)
Disease	serum IgG glycosylation measurement	GPM6A FRY EYS USH2A ANKFN1 ITGB3	2.47e-03	523	77	6	EFO_0005193

Protein segments in the cluster

Peptide	Gene	Start	Entry
EMTCNSKISCISWSS	COP1	466	Q8NHY2
LVEDATCVTCMSDSS	AKAP1	481	Q92667
TCVTCMSDSSQSVPL	AKAP1	486	Q92667
SWTCINTTLTCEVMN	CD2	136	P06729
SFTCCMAASVTTLNS	GSG1L	226	Q6UXU4
TTTCTMGQTKCFISI	ADGRV1	5436	Q8WXG9
MAEAISCTLNCSCQS	BNC1	31	Q01954
ASKAMSDDTVTAVCC	CTNND2	951	Q9UQB3
SSTVPVMSASCRTNC	ARPP21	786	Q9UBL0
ACAVRVTELCSSTMT	CHML	486	P26374
QLCSIEVTCESASVM	GLS	416	O94925
CGCISSVIQTSMTFT	OR9K2	176	Q8NGE7
IENTTDCLSTMTSVC	CYRIA	216	Q9H0Q0
CTLCSMEGDSVSSES	KCNE4	166	Q8WWG9
TELNMACNSTQSDTC	KCNC2	511	Q96PR1
ELSQTCATCSMTEIK	EYS	1551	Q5T1H1
ICTVSENFLRMCEST	GPM6A	191	P51674
MTSSCCVTNNLQASL	KRT32	1	Q14532
SACFTASCTLMALAS	SLC43A1	111	O75387
DSCISSVMCDNASIV	FBXW12	431	Q6X9E4
ACLSVVAQTFMDSCS	PLXNA1	1771	Q9UIW2
ACLSVVAQTFMDSCS	PLXNA3	1746	P51805
CECVTQPTTMTTTTT	MUC2	1876	Q02817
SESCLMLSASSCAER	FGD5	1181	Q6ZNL6
ECRMSGECTSQVTIS	KRT78	421	Q8N1N4
STCTSHMCSIVITYV	OR52N2	241	Q8NGI0
CTSMASENSECSVKT	CLPS	56	P04118
QTMSVLISCTTCHSE	DNAJC21	476	Q5F1R6
CIISTIMESCPSTSS	HUWE1	2181	Q7Z6Z7
QTACMSACQHLSTSL	EXOC6	656	Q8TAG9
TCQVPDSMTSAACFS	ITGA8	506	P53708
DCVTIATCTTNETMC	LYPD2	36	Q6UXB3
ATCTTNETMCKTTLY	LYPD2	41	Q6UXB3
CSNSCSSFILMDDLS	PABIR2	231	Q7Z309
SSSSKVCMEATGCTR	OBSCN	931	Q5VST9
MNLSIVMTTCSTFCA	SLC10A1	116	Q14973
ACTAVRNCVMSLCSS	HTT	826	P42858
MCSLSVCDSKRNLSS	CHD6	1826	Q8TD26
CISCASSAREMKSIT	IL26	121	Q9NPH9
CMNTTLTECDFSSLS	IL10RB	66	Q08334
VSENFSCNITLMCSV	LY9	166	Q9HBG7
CTTRTDTCMSSNGLL	ITGB3	586	P05106
ANSTCQLIVCQMSST	SELENOI	301	Q9C0D9
ENMSECETSSVCSSS	GPATCH2L	216	Q9NWQ4
CSQESSVSALLASCT	LAS2	11	Q8IYD9
MAASTMSICSSACTN	KRTAP10-2	1	P60368
MVSSCCGSVSSEQSC	KRTAP4-5	1	Q9BYR2
STNTMTIRVCRCDSD	CDH12	581	P55289
VESLCVMETASNFSC	FBXL5	501	Q9UKA1
SEACVSVTSSILSSM	ECE1	101	P42892
VSSSQMLTSCSECPT	FRY	2741	Q5TBA9
TDCRTSCDQSTMKCT	DIPK1A	341	Q5T7M9
TASCTSDLCQSMGDV	OTOG	371	Q6ZRI0
SCCSEAVKSAMSTID	MN1	1201	Q10571
MSDTICCSASSGESK	USH2A	3331	O75445
VSEMSCSESTSSCQS	SYT14	396	Q8NB59
TSTTMISACVSRCVQ	GFM2	661	Q969S9
TCLEMNATKTQSNCS	SSPOP	4946	A2VEC9
MATRQRESSITSCCS	LCMT1	1	Q9UIC8
ACTSCTFVTSVGDAM	POGZ	816	Q7Z3K3
TMPASSSQTCCTDHQ	NEO1	1311	Q92859
LMASVNSTCNVTLTC	CD84	141	Q9UIB8
LSSVTLSTTCGQMAS	SLC25A41	286	Q8N5S1
PCSTFCTSEINSMSA	SLC41A3	361	Q96GZ6
SEMSCSESTSACQSL	SYT14P1	31	Q58G82
NVCLMVTSSTSLTVS	ANKFN1	276	Q8N957
SKMVYQTSLCSCSVN	MRPL1	21	Q9BYD6
MASAITQCSTSELTC	TRIM77	1	I1YAP6
CSLDDTDMSCNPTST	TRIM77	311	I1YAP6
RFCESCMAALLSSSS	TRAF3	71	Q13114
SCTEDLSSCTSVPEM	WWC2	921	Q6AWC2
CFSMEETQGELTSSC	ZNF546	36	Q86UE3
SCGASDCLMATTTTN	UNC93A	176	Q86WB7
CLVNMETSCSFDSSI	WAPL	1001	Q7Z5K2
DSCISSSASEMESCS	SENP6	801	Q9GZR1
TCIASTTQTIEQMYC	USP28	561	Q96RU2
LIRCCNVSSTMQSSI	USP9Y	2236	O00507
MCSVVPTLCSSSDNA	TASOR2	1651	Q5VWN6
LICVDCAMESSRNSS	USP18	176	Q9UMW8
CSSSSECLEDSTMGS	PLK2	456	Q9NYY3
CNEESLICMNTSTSY	VEGFD	146	O43915
CCTLCNMSFTSAVVA	ZMAT4	76	Q9H898
ESCSRDSMSSQPSCT	ZMYM3	1046	Q14202
MVSSPCTQASSRTCS	TM4SF19	1	Q96DZ7
TDSSMERVSPSTCCS	N4BP2	716	Q86UW6