Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	2.55e-06	5	128	3	GO:0030156
GeneOntologyMolecularFunction	actin binding	MYH8 CORO2A SYNE1 SPTBN2 SPTBN4 SPTBN5 SHROOM1 MYH14 SSH3 MACF1 SSH2 DMD UTRN	1.28e-05	479	128	13	GO:0003779
GeneOntologyMolecularFunction	actin filament binding	MYH8 CORO2A SYNE1 SPTBN2 SPTBN4 SPTBN5 SHROOM1 MYH14 MACF1	1.60e-05	227	128	9	GO:0051015
GeneOntologyMolecularFunction	cytoskeletal protein binding	KIF13B CACNA1D MYH8 ANK1 CORO2A SYNE1 SPTBN2 CKAP5 CCDC88B SPTBN4 SPTBN5 SHROOM1 MYH14 SSH3 MACF1 SSH2 DMD ALDOC UTRN	7.36e-05	1099	128	19	GO:0008092
GeneOntologyMolecularFunction	histone H3K4me/H3K4me2/H3K4me3 demethylase activity	KDM5A KDM5C	6.01e-04	6	128	2	GO:0034647
GeneOntologyBiologicalProcess	negative regulation of actin filament polymerization	SPTBN2 SPTBN4 SPTBN5 SSH3 KANK3 SSH2	6.28e-06	75	125	6	GO:0030837
GeneOntologyBiologicalProcess	negative regulation of protein polymerization	SPTBN2 SPTBN4 SPTBN5 SSH3 KANK3 SSH2	1.92e-05	91	125	6	GO:0032272
GeneOntologyBiologicalProcess	intermediate filament cytoskeleton organization	ARHGEF28 KRT27 KRT40 MACF1 KRT25 KRT36	3.11e-05	99	125	6	GO:0045104
GeneOntologyBiologicalProcess	intermediate filament-based process	ARHGEF28 KRT27 KRT40 MACF1 KRT25 KRT36	3.29e-05	100	125	6	GO:0045103
GeneOntologyCellularComponent	supramolecular fiber	KIF13B CACNA1D MYH8 ILK ANK1 TCHP KRT27 SYNE1 CKAP5 CCDC57 SPTBN4 SAA1 SAA2 SHROOM1 MYH14 RP1L1 KRT40 MACF1 DMD KRT25 KRT36	1.08e-05	1179	129	21	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	KIF13B CACNA1D MYH8 ILK ANK1 TCHP KRT27 SYNE1 CKAP5 CCDC57 SPTBN4 SAA1 SAA2 SHROOM1 MYH14 RP1L1 KRT40 MACF1 DMD KRT25 KRT36	1.19e-05	1187	129	21	GO:0099081
GeneOntologyCellularComponent	spectrin	SPTBN2 SPTBN4 SPTBN5	1.88e-05	9	129	3	GO:0008091
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	KIF13B TCHP KRT27 CKAP5 CCDC57 SPTBN4 SAA1 SAA2 SHROOM1 RP1L1 KRT40 MACF1 DMD KRT25 KRT36	4.38e-04	899	129	15	GO:0099513
GeneOntologyCellularComponent	intermediate filament	TCHP KRT27 KRT40 MACF1 DMD KRT25 KRT36	5.29e-04	227	129	7	GO:0005882
GeneOntologyCellularComponent	manchette	RIMBP3 RIMBP3C RIMBP3B	6.72e-04	28	129	3	GO:0002177
GeneOntologyCellularComponent	centriole	CCHCR1 CCDC57 CNTROB SPICE1 CEP250 TSKS	7.02e-04	172	129	6	GO:0005814
GeneOntologyCellularComponent	axon	NRN1L CACNA1B KIF13B ILK ANK1 ACHE PPFIA1 COPG2 SPTBN4 MYH14 SEMA6A TRPM1 DMD ALDOC	1.22e-03	891	129	14	GO:0030424
GeneOntologyCellularComponent	cortical cytoskeleton	ANK1 SPTBN2 SPTBN4 SPTBN5 SHROOM1	1.24e-03	129	129	5	GO:0030863
GeneOntologyCellularComponent	intermediate filament cytoskeleton	TCHP KRT27 KRT40 MACF1 DMD KRT25 KRT36	1.25e-03	263	129	7	GO:0045111
GeneOntologyCellularComponent	spectrin-associated cytoskeleton	ANK1 SPTBN2	1.32e-03	9	129	2	GO:0014731
GeneOntologyCellularComponent	apical cortex	TCHP SPTBN5	1.65e-03	10	129	2	GO:0045179
Domain	Spectrin	SYNE1 SPTBN2 SPTBN4 SPTBN5 MACF1 DMD UTRN	9.59e-11	23	122	7	PF00435
Domain	ACTININ_2	SYNE1 SPTBN2 SPTBN4 SPTBN5 MACF1 DMD UTRN	9.59e-11	23	122	7	PS00020
Domain	ACTININ_1	SYNE1 SPTBN2 SPTBN4 SPTBN5 MACF1 DMD UTRN	9.59e-11	23	122	7	PS00019
Domain	Actinin_actin-bd_CS	SYNE1 SPTBN2 SPTBN4 SPTBN5 MACF1 DMD UTRN	9.59e-11	23	122	7	IPR001589
Domain	Spectrin_repeat	SYNE1 SPTBN2 SPTBN4 SPTBN5 MACF1 DMD UTRN	5.91e-10	29	122	7	IPR002017
Domain	SPEC	SYNE1 SPTBN2 SPTBN4 SPTBN5 MACF1 DMD UTRN	1.25e-09	32	122	7	SM00150
Domain	Spectrin/alpha-actinin	SYNE1 SPTBN2 SPTBN4 SPTBN5 MACF1 DMD UTRN	1.25e-09	32	122	7	IPR018159
Domain	CH	SYNE1 SPTBN2 SPTBN4 SPTBN5 MACF1 DMD UTRN	2.17e-07	65	122	7	SM00033
Domain	CH	SYNE1 SPTBN2 SPTBN4 SPTBN5 MACF1 DMD UTRN	3.64e-07	70	122	7	PF00307
Domain	-	SYNE1 SPTBN2 SPTBN4 SPTBN5 MACF1 DMD UTRN	4.01e-07	71	122	7	1.10.418.10
Domain	CH	SYNE1 SPTBN2 SPTBN4 SPTBN5 MACF1 DMD UTRN	4.86e-07	73	122	7	PS50021
Domain	CH-domain	SYNE1 SPTBN2 SPTBN4 SPTBN5 MACF1 DMD UTRN	5.86e-07	75	122	7	IPR001715
Domain	PH_dom-spectrin-type	SPTBN2 SPTBN4 SPTBN5	2.22e-05	9	122	3	IPR001605
Domain	Dystrophin	DMD UTRN	4.23e-05	2	122	2	IPR016344
Domain	Ssh	SSH3 SSH2	4.23e-05	2	122	2	IPR027232
Domain	CAP	CLEC18A CLEC18B CLEC18C	1.17e-04	15	122	3	PF00188
Domain	SCP	CLEC18A CLEC18B CLEC18C	1.17e-04	15	122	3	SM00198
Domain	Allrgn_V5/Tpx1	CLEC18A CLEC18B CLEC18C	1.17e-04	15	122	3	IPR001283
Domain	-	CLEC18A CLEC18B CLEC18C	1.17e-04	15	122	3	3.40.33.10
Domain	CAP_domain	CLEC18A CLEC18B CLEC18C	1.17e-04	15	122	3	IPR014044
Domain	Keratin_I	KRT27 KRT40 KRT25 KRT36	1.92e-04	44	122	4	IPR002957
Domain	Lys_sp_deMease-like_dom	KDM5A KDM5C	2.52e-04	4	122	2	IPR013637
Domain	SAA	SAA1 SAA2	2.52e-04	4	122	2	PS00992
Domain	RNase_II/R_CS	DIS3 HELZ2	2.52e-04	4	122	2	IPR022966
Domain	Spectrin_bsu	SPTBN2 SPTBN4	2.52e-04	4	122	2	IPR016343
Domain	SAA	SAA1 SAA2	2.52e-04	4	122	2	SM00197
Domain	DEK_C	SSH3 SSH2	2.52e-04	4	122	2	PF08766
Domain	DEK_C	SSH3 SSH2	2.52e-04	4	122	2	IPR014876
Domain	PLU-1	KDM5A KDM5C	2.52e-04	4	122	2	PF08429
Domain	SAA	SAA1 SAA2	2.52e-04	4	122	2	PF00277
Domain	zf-C5HC2	KDM5A KDM5C	4.18e-04	5	122	2	PF02928
Domain	Znf_C5HC2	KDM5A KDM5C	4.18e-04	5	122	2	IPR004198
Domain	Serum_amyloid_A	SAA1 SAA2	4.18e-04	5	122	2	IPR000096
Domain	EF-hand_dom_typ1	DMD UTRN	6.24e-04	6	122	2	IPR015153
Domain	EF-hand_dom_typ2	DMD UTRN	6.24e-04	6	122	2	IPR015154
Domain	EF-hand_2	DMD UTRN	6.24e-04	6	122	2	PF09068
Domain	EF-hand_3	DMD UTRN	6.24e-04	6	122	2	PF09069
Domain	Ca_chan_IQ	CACNA1B CACNA1D	8.70e-04	7	122	2	SM01062
Domain	Ca_chan_IQ	CACNA1B CACNA1D	8.70e-04	7	122	2	PF08763
Domain	VDCC_a1su_IQ	CACNA1B CACNA1D	8.70e-04	7	122	2	IPR014873
Domain	GPHH	CACNA1B CACNA1D	8.70e-04	7	122	2	PF16905
Domain	GPHH_dom	CACNA1B CACNA1D	8.70e-04	7	122	2	IPR031649
Domain	Carbohydrate_sulfotransferase	CHST4 CHST2	8.70e-04	7	122	2	IPR016469
Domain	Ion_trans_dom	CACNA1B CACNA1D KCNG3 TRPV6 TRPM1	9.12e-04	114	122	5	IPR005821
Domain	Ion_trans	CACNA1B CACNA1D KCNG3 TRPV6 TRPM1	9.12e-04	114	122	5	PF00520
Domain	Filament	KRT27 KRT40 KRT25 KRT36	1.20e-03	71	122	4	SM01391
Domain	IF	KRT27 KRT40 KRT25 KRT36	1.27e-03	72	122	4	PS00226
Domain	Filament	KRT27 KRT40 KRT25 KRT36	1.33e-03	73	122	4	PF00038
Domain	IF	KRT27 KRT40 KRT25 KRT36	1.55e-03	76	122	4	IPR001664
Domain	JmjN	KDM5A KDM5C	1.84e-03	10	122	2	SM00545
Domain	JmjN	KDM5A KDM5C	1.84e-03	10	122	2	PF02375
Domain	JMJN	KDM5A KDM5C	1.84e-03	10	122	2	PS51183
Domain	VDCCAlpha1	CACNA1B CACNA1D	1.84e-03	10	122	2	IPR002077
Domain	JmjN	KDM5A KDM5C	1.84e-03	10	122	2	IPR003349
Domain	SH3_2	RIMBP3 MIA2 RIMBP3C RIMBP3B	2.44e-03	86	122	4	PF07653
Domain	SH3_2	RIMBP3 MIA2 RIMBP3C RIMBP3B	2.44e-03	86	122	4	IPR011511
Domain	C-type_lectin_CS	CLEC18A CLEC18B CLEC18C	2.77e-03	43	122	3	IPR018378
Domain	-	KDM5A KDM5C	4.20e-03	15	122	2	1.10.150.60
Domain	BRIGHT	KDM5A KDM5C	4.20e-03	15	122	2	SM00501
Domain	ARID_dom	KDM5A KDM5C	4.20e-03	15	122	2	IPR001606
Domain	ARID	KDM5A KDM5C	4.20e-03	15	122	2	PS51011
Domain	Myosin_N	MYH8 MYH14	4.20e-03	15	122	2	PF02736
Domain	ARID	KDM5A KDM5C	4.20e-03	15	122	2	PF01388
Domain	Myosin_N	MYH8 MYH14	4.20e-03	15	122	2	IPR004009
Domain	HEAT_type_2	PPP4R1 CKAP5	5.40e-03	17	122	2	IPR021133
Domain	Myosin_tail_1	MYH8 MYH14	6.05e-03	18	122	2	PF01576
Domain	Myosin_tail	MYH8 MYH14	6.05e-03	18	122	2	IPR002928
Domain	ZF_ZZ_2	DMD UTRN	6.05e-03	18	122	2	PS50135
Domain	ZF_ZZ_1	DMD UTRN	6.05e-03	18	122	2	PS01357
Domain	ZZ	DMD UTRN	6.05e-03	18	122	2	PF00569
Domain	Channel_four-helix_dom	CACNA1B CACNA1D KCNG3	6.16e-03	57	122	3	IPR027359
Domain	-	CACNA1B CACNA1D KCNG3	6.16e-03	57	122	3	1.20.120.350
Domain	-	CORO2A DCAF5 TBC1D31 TECPR2 SEMA6A ATG16L2 SON	6.28e-03	333	122	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	CORO2A DCAF5 TBC1D31 TECPR2 SEMA6A ATG16L2 SON	6.48e-03	335	122	7	IPR015943
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	ANK1 SPTBN2 SPTBN4 SPTBN5	3.17e-07	10	90	4	MM15112
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	ANK1 SPTBN2 SPTBN4 SPTBN5	4.28e-05	31	90	4	M877
Pathway	KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE	CHST4 B3GNT2 CHST2	1.08e-04	15	90	3	M3042
Pubmed	Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity.	CLEC18A CLEC18B CLEC18C	4.99e-08	3	129	3	26170455
Pubmed	The C-type lectin-like domain superfamily.	CLEC18A CLEC18B CLEC18C	4.99e-08	3	129	3	16336259
Pubmed	Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection.	CLEC18A CLEC18B CLEC18C	4.99e-08	3	129	3	33603190
Pubmed	The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation.	CLEC18A CLEC18B CLEC18C	1.99e-07	4	129	3	16709836
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	1.99e-07	4	129	3	19091768
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PPP4R1 PPFIA1 SPTBN2 COPG2 CCDC115 CNTROB SPICE1 IPO9 TBC1D31 AIFM1 SSH3 LRRC1 PDP2 SSH2 DMD UTRN YME1L1	3.70e-07	1049	129	17	27880917
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	4.96e-07	5	129	3	17855024
Pubmed	Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin.	ACHE DMD UTRN	8.05e-06	11	129	3	10995443
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TCHP DNAJC8 SYNE1 PPFIA1 SPTBN2 SPART CCDC115 DCAF5 SPICE1 TBC1D31 AIFM1 LRRC1 DDRGK1 MACF1 SEMA6A TMX3 YME1L1 VPS13B	1.00e-05	1487	129	18	33957083
Pubmed	The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain.	KRT27 KRT40 KRT25	1.07e-05	12	129	3	15617563
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	KDM5A DNAJC8 SYNE1 PPFIA1 CKAP5 LAMB2 COPG2 MEN1 RBM19 TRIM56 MDC1 HELZ2 DDRGK1 MACF1 UTRN YME1L1 HOMER3 SON	1.10e-05	1497	129	18	31527615
Pubmed	Polymorphisms in the SAA1/2 gene are associated with carotid intima media thickness in healthy Han Chinese subjects: the Cardiovascular Risk Survey.	SAA1 SAA2	1.37e-05	2	129	2	21103356
Pubmed	The rate and significance of type 1/type 2 serum amyloid A protein gene polymorphisms in patients with ankylosing spondylitis and amyloidosis.	SAA1 SAA2	1.37e-05	2	129	2	26300108
Pubmed	Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy.	DMD UTRN	1.37e-05	2	129	2	10525423
Pubmed	Distribution of dystrophin- and utrophin-associated protein complexes during activation of human neutrophils.	DMD UTRN	1.37e-05	2	129	2	20434517
Pubmed	A novel, high endothelial venule-specific sulfotransferase expresses 6-sulfo sialyl Lewis(x), an L-selectin ligand displayed by CD34.	CHST4 CHST2	1.37e-05	2	129	2	10435581
Pubmed	DNA sequence evidence for polymorphic forms of human serum amyloid A (SAA).	SAA1 SAA2	1.37e-05	2	129	2	3800865
Pubmed	Plasma lipidomic analysis shows a disease progression signature in mdx mice.	DMD UTRN	1.37e-05	2	129	2	34155298
Pubmed	In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.	DMD UTRN	1.37e-05	2	129	2	28790199
Pubmed	Dystrophic changes in extraocular muscles after gamma irradiation in mdx:utrophin(+/-) mice.	DMD UTRN	1.37e-05	2	129	2	24466085
Pubmed	LRRC1 knockdown downregulates MACF1 to inhibit the malignant progression of acute myeloid leukemia by inactivating β-catenin/c-Myc signaling.	LRRC1 MACF1	1.37e-05	2	129	2	38165568
Pubmed	The Angiotensin Converting Enzyme Inhibitor Lisinopril Improves Muscle Histopathology but not Contractile Function in a Mouse Model of Duchenne Muscular Dystrophy.	DMD UTRN	1.37e-05	2	129	2	27110493
Pubmed	Rapid depletion of muscle progenitor cells in dystrophic mdx/utrophin-/- mice.	DMD UTRN	1.37e-05	2	129	2	24781208
Pubmed	Serum Amyloid A Promotes Inflammation-Associated Damage and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer.	SAA1 SAA2	1.37e-05	2	129	2	34217896
Pubmed	Serum amyloid A, an acute phase protein, inhibits platelet activation.	SAA1 SAA2	1.37e-05	2	129	2	1697614
Pubmed	Isolation and characterization of a genomic clone from the murine utrophin locus.	DMD UTRN	1.37e-05	2	129	2	8268660
Pubmed	Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.	DMD UTRN	1.37e-05	2	129	2	25859846
Pubmed	G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain.	DMD UTRN	1.37e-05	2	129	2	7731967
Pubmed	Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells.	SAA1 SAA2	1.37e-05	2	129	2	26937641
Pubmed	Characterization of neuromuscular synapse function abnormalities in multiple Duchenne muscular dystrophy mouse models.	DMD UTRN	1.37e-05	2	129	2	27037492
Pubmed	Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue.	DMD UTRN	1.37e-05	2	129	2	16710609
Pubmed	Improvement in survival and muscle function in an mdx/utrn(-/-) double mutant mouse using a human retinal dystrophin transgene.	DMD UTRN	1.37e-05	2	129	2	16487708
Pubmed	Nonclinical Exon Skipping Studies with 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides in mdx and mdx-utrn-/- Mice Inspired by Clinical Trial Results.	DMD UTRN	1.37e-05	2	129	2	30672725
Pubmed	Serum amyloid A facilitates the binding of high-density lipoprotein from mice injected with lipopolysaccharide to vascular proteoglycans.	SAA1 SAA2	1.37e-05	2	129	2	21474830
Pubmed	Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart.	DMD UTRN	1.37e-05	2	129	2	21677768
Pubmed	Talin, vinculin and DRP (utrophin) concentrations are increased at mdx myotendinous junctions following onset of necrosis.	DMD UTRN	1.37e-05	2	129	2	7962191
Pubmed	Consequences of the combined deficiency in dystrophin and utrophin on the mechanical properties and myosin composition of some limb and respiratory muscles of the mouse.	DMD UTRN	1.37e-05	2	129	2	9713852
Pubmed	Skeletal muscle fibrosis in the mdx/utrn+/- mouse validates its suitability as a murine model of Duchenne muscular dystrophy.	DMD UTRN	1.37e-05	2	129	2	25607927
Pubmed	Does utrophin expression in muscles of mdx mice during postnatal development functionally compensate for dystrophin deficiency?	DMD UTRN	1.37e-05	2	129	2	8021701
Pubmed	Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.	DMD UTRN	1.37e-05	2	129	2	26974331
Pubmed	Developmental studies of dystrophin-positive fibers in mdx, and DRP localization.	DMD UTRN	1.37e-05	2	129	2	8433092
Pubmed	Second-generation compound for the modulation of utrophin in the therapy of DMD.	DMD UTRN	1.37e-05	2	129	2	25935002
Pubmed	Utrophin deficiency worsens cardiac contractile dysfunction present in dystrophin-deficient mdx mice.	DMD UTRN	1.37e-05	2	129	2	16024571
Pubmed	Structure of a human serum amyloid A gene and modulation of its expression in transfected L cells.	SAA1 SAA2	1.37e-05	2	129	2	2890635
Pubmed	Influence of Serum Amyloid A (SAA1) and SAA2 gene polymorphisms on renal amyloidosis, and on SAA/C-reactive protein values in patients with familial mediterranean fever in the Turkish population.	SAA1 SAA2	1.37e-05	2	129	2	15170927
Pubmed	Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy.	DMD UTRN	1.37e-05	2	129	2	28453658
Pubmed	Acute-phase, but not constitutive serum amyloid A (SAA) is chemotactic for cultured human aortic smooth muscle cells.	SAA1 SAA2	1.37e-05	2	129	2	12557751
Pubmed	Serum amyloid alpha 1-2 are not required for liver inflammation in the 4T1 murine breast cancer model.	SAA1 SAA2	1.37e-05	2	129	2	36817472
Pubmed	A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin.	DMD UTRN	1.37e-05	2	129	2	11801396
Pubmed	Association of genetic variation in serum amyloid-A with cardiovascular disease and interactions with IL6, IL1RN, IL1beta and TNF genes in the Cardiovascular Health Study.	SAA1 SAA2	1.37e-05	2	129	2	19729864
Pubmed	Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines.	DMD UTRN	1.37e-05	2	129	2	7987307
Pubmed	Utility of dystrophin and utrophin staining in childhood muscular dystrophy.	DMD UTRN	1.37e-05	2	129	2	16295426
Pubmed	Comparative analysis of the human dystrophin and utrophin gene structures.	DMD UTRN	1.37e-05	2	129	2	11861579
Pubmed	Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications.	SAA1 SAA2	1.37e-05	2	129	2	16737350
Pubmed	Distinct mechanical properties in homologous spectrin-like repeats of utrophin.	DMD UTRN	1.37e-05	2	129	2	30914715
Pubmed	Murine apolipoprotein serum amyloid A in solution forms a hexamer containing a central channel.	SAA1 SAA2	1.37e-05	2	129	2	12456883
Pubmed	Dystrophin is a microtubule-associated protein.	DMD UTRN	1.37e-05	2	129	2	19651889
Pubmed	Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice.	DMD UTRN	1.37e-05	2	129	2	9590295
Pubmed	Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains.	DMD UTRN	1.37e-05	2	129	2	22284942
Pubmed	The Impairment of Macrophage-to-Feces Reverse Cholesterol Transport during Inflammation Does Not Depend on Serum Amyloid A.	SAA1 SAA2	1.37e-05	2	129	2	23431457
Pubmed	Utrophin haploinsufficiency does not worsen the functional performance, resistance to eccentric contractions and force production of dystrophic mice.	DMD UTRN	1.37e-05	2	129	2	29879154
Pubmed	Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice.	DMD UTRN	1.37e-05	2	129	2	17889902
Pubmed	Identification of Dp71 isoforms in the platelet membrane cytoskeleton. Potential role in thrombin-mediated platelet adhesion.	DMD UTRN	1.37e-05	2	129	2	12370193
Pubmed	Longitudinal metabolomic analysis of plasma enables modeling disease progression in Duchenne muscular dystrophy mouse models.	DMD UTRN	1.37e-05	2	129	2	32025735
Pubmed	Lifelong quercetin enrichment and cardioprotection in Mdx/Utrn+/- mice.	DMD UTRN	1.37e-05	2	129	2	27836895
Pubmed	Large-scale isotype-specific quantification of Serum amyloid A 1/2 by multiple reaction monitoring in crude sera.	SAA1 SAA2	1.37e-05	2	129	2	22300576
Pubmed	Extracellular matrix-anchored serum amyloid A preferentially induces mast cell adhesion.	SAA1 SAA2	1.37e-05	2	129	2	9252455
Pubmed	No evidence for a role of adipose tissue-derived serum amyloid a in the development of insulin resistance or obesity-related inflammation in hSAA1(+/-) transgenic mice.	SAA1 SAA2	1.37e-05	2	129	2	23967285
Pubmed	BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle.	DMD UTRN	1.37e-05	2	129	2	27750047
Pubmed	Essential role of peripheral node addressin in lymphocyte homing to nasal-associated lymphoid tissues and allergic immune responses.	CHST4 CHST2	1.37e-05	2	129	2	21518796
Pubmed	Inflammatory remodeling of the HDL proteome impairs cholesterol efflux capacity.	SAA1 SAA2	1.37e-05	2	129	2	25995210
Pubmed	Diversity and complexity of the mouse Saa1 and Saa2 genes.	SAA1 SAA2	1.37e-05	2	129	2	24521869
Pubmed	Prevention of dystrophin-deficient cardiomyopathy in twenty-one-month-old carrier mice by mosaic dystrophin expression or complementary dystrophin/utrophin expression.	DMD UTRN	1.37e-05	2	129	2	17967782
Pubmed	Diaphragm rescue alone prevents heart dysfunction in dystrophic mice.	DMD UTRN	1.37e-05	2	129	2	21062902
Pubmed	Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression.	DMD UTRN	1.37e-05	2	129	2	35557546
Pubmed	Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice.	DMD UTRN	1.37e-05	2	129	2	37626761
Pubmed	A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules.	CHST4 CHST2	1.37e-05	2	129	2	16227986
Pubmed	Linkage of protection against amyloid fibril formation in the mouse to a single, autosomal dominant gene.	SAA1 SAA2	1.37e-05	2	129	2	7760010
Pubmed	Serum amyloid A exhibits pH dependent antibacterial action and contributes to host defense against Staphylococcus aureus cutaneous infection.	SAA1 SAA2	1.37e-05	2	129	2	31819008
Pubmed	Molecular heterogeneity of the dystrophin-associated protein complex in the mouse kidney nephron: differential alterations in the absence of utrophin and dystrophin.	DMD UTRN	1.37e-05	2	129	2	15565469
Pubmed	SAA does not induce cytokine production in physiological conditions.	SAA1 SAA2	1.37e-05	2	129	2	23165195
Pubmed	Heterogeneity of human serum amyloid A protein. Five different variants from one individual demonstrated by cDNA sequence analysis.	SAA1 SAA2	1.37e-05	2	129	2	1971508
Pubmed	The N- and C-Terminal Domains Differentially Contribute to the Structure and Function of Dystrophin and Utrophin Tandem Calponin-Homology Domains.	DMD UTRN	1.37e-05	2	129	2	26516677
Pubmed	Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging.	DMD UTRN	1.37e-05	2	129	2	22209498
Pubmed	β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees: protein complex critical for sodium channel activity is impaired by SCA5-associated mutations.	ANK1 SPTBN2	1.37e-05	2	129	2	24603075
Pubmed	Serum amyloid A induces calcium mobilization and chemotaxis of human monocytes by activating a pertussis toxin-sensitive signaling pathway.	SAA1 SAA2	1.37e-05	2	129	2	7561109
Pubmed	A Protocol for Simultaneous In Vivo Imaging of Cardiac and Neuroinflammation in Dystrophin-Deficient MDX Mice Using [18F]FEPPA PET.	DMD UTRN	1.37e-05	2	129	2	37108685
Pubmed	Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.	DMD UTRN	1.37e-05	2	129	2	10694796
Pubmed	Dystrophin and dystrophin-related protein in the central nervous system of normal controls and Duchenne muscular dystrophy.	DMD UTRN	1.37e-05	2	129	2	8171962
Pubmed	Similar efficacy from specific and non-specific mineralocorticoid receptor antagonist treatment of muscular dystrophy mice.	DMD UTRN	1.37e-05	2	129	2	27822449
Pubmed	Human serum amyloid A. Three hepatic mRNAs and the corresponding proteins in one person.	SAA1 SAA2	1.37e-05	2	129	2	3183061
Pubmed	Micro-dystrophin gene therapy prevents heart failure in an improved Duchenne muscular dystrophy cardiomyopathy mouse model.	DMD UTRN	1.37e-05	2	129	2	33651713
Pubmed	Complete primary structures of two major murine serum amyloid A proteins deduced from cDNA sequences.	SAA1 SAA2	1.37e-05	2	129	2	3857624
Pubmed	Thermodynamic stability, unfolding kinetics, and aggregation of the N-terminal actin-binding domains of utrophin and dystrophin.	DMD UTRN	1.37e-05	2	129	2	22275054
Pubmed	NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.	DMD UTRN	1.37e-05	2	129	2	27798264
Pubmed	Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice.	DMD UTRN	1.37e-05	2	129	2	31506484
Pubmed	A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells.	SAA1 SAA2	1.37e-05	2	129	2	9892621
Pubmed	Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy.	DMD UTRN	1.37e-05	2	129	2	9288752
Pubmed	Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy.	DMD UTRN	1.37e-05	2	129	2	9288751
Pubmed	Specificities of N-acetylglucosamine-6-O-sulfotransferases in relation to L-selectin ligand synthesis and tumor-associated enzyme expression.	CHST4 CHST2	1.37e-05	2	129	2	11726653
Interaction	KRT4 interactions	KRT27 CCDC57 B3GNT2 KRT40 KRT25 KRT36	2.45e-06	62	126	6	int:KRT4
Interaction	DTNB interactions	CCHCR1 KRT27 PPFIA1 CCDC88B KRT40 DMD UTRN	3.34e-06	101	126	7	int:DTNB
Interaction	CEP63 interactions	PPP4R1 CCHCR1 TCHP SYNE1 SPICE1 TBC1D31 KRT40 MACF1	1.71e-05	179	126	8	int:CEP63
Interaction	PPP1R18 interactions	KRT27 CCDC57 CCDC88B CARD9 KRT40 HOMER3 KRT36	2.98e-05	141	126	7	int:PPP1R18
Interaction	ATG16L1 interactions	PPP4R1 CCHCR1 USP13 ARHGEF28 TCHP CORO2A KRT27 PPFIA1 CKAP5 DIS3 SPICE1 SHROOM1 IPO9 ARAP3 TRIM56 CEP250 HELZ2 DDRGK1 YME1L1 ATG16L2	3.41e-05	1161	126	20	int:ATG16L1
Cytoband	Ensembl 112 genes in cytogenetic band chr16q22	NRN1L CLEC18A CLEC18C CHST4 PDP2	1.76e-04	183	129	5	chr16q22
Cytoband	16q22.1	NRN1L CLEC18A CLEC18C PDP2	2.73e-04	110	129	4	16q22.1
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN2 SPTBN4 SPTBN5	3.46e-06	7	85	3	1113
GeneFamily	Keratins, type I	KRT27 KRT40 KRT25 KRT36	8.55e-06	28	85	4	608
GeneFamily	Slingshot protein phosphatases	SSH3 SSH2	6.53e-05	3	85	2	898
GeneFamily	Sulfotransferases, membrane bound	GAL3ST4 CHST4 CHST2	6.94e-04	37	85	3	763
GeneFamily	C-type lectin domain family	CLEC18A CLEC18B CLEC18C	1.40e-03	47	85	3	494
GeneFamily	AT-rich interaction domain containing	KDM5A KDM5C	2.20e-03	15	85	2	418
GeneFamily	Myosin heavy chains	MYH8 MYH14	2.20e-03	15	85	2	1098
GeneFamily	Ubiquitin specific peptidases	USP13 USP43 USP19	2.32e-03	56	85	3	366
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM13 PRDM15	2.84e-03	17	85	2	1197
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	DMD UTRN	3.18e-03	18	85	2	91
GeneFamily	Carboxypeptidases	CPXM2 CPN2	4.33e-03	21	85	2	1321
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM5A KDM5C	5.64e-03	24	85	2	485
GeneFamily	Ankyrin repeat domain containing	ILK ANK1 ARAP3 KANK3 TRPV6	5.67e-03	242	85	5	403
GeneFamily	Calcium voltage-gated channel subunits	CACNA1B CACNA1D	6.60e-03	26	85	2	253
GeneFamily	Transient receptor potential cation channels	TRPV6 TRPM1	7.63e-03	28	85	2	249
Coexpression	GSE3982_EOSINOPHIL_VS_MAST_CELL_UP	KDM5C NLRX1 GAL3ST4 USP19 CSF2RB FOLH1B SLC27A3 ZNF292	6.67e-06	199	129	8	M5397
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANK1 ACHE EXPH5 PRSS56 TMTC4 LRRC1 PLCE1	8.01e-07	175	129	7	9d09636a103daa8f622c3dbfd1f1536aaec3b6bb
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCHCR1 ALKBH7 LAMB2 COPG2 ARAP3 SEMA6A GIMAP6	8.64e-07	177	129	7	8ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN4 SAA1 SAA2 ARAP3 CHST2 CCT8L1P HOMER3	1.54e-06	193	129	7	2483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCell	(4)_Endothelial_cells-(42)_EC-sinusoidal\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	ARAP3 CSF2RB KANK3 ANGPTL4 SEMA6A CHST2 GIMAP6	1.59e-06	194	129	7	4428b472c2042f88eae028b1770767512a515b75
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Calb1_(Superficial_layer_pyramidal_cells--Layer_2/3)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CLEC18A EXPH5 KCNG3 LCT LIAT1 TSKS	1.84e-06	126	129	6	7dcc79bf35482e8e5e5a1de7279ba080edb70522
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CLVS1 TLR8 ARAP3 CSF2RB TMTC4 SLC22A4	4.67e-06	148	129	6	fd0d8386b94adb1bdc993fbb44d2d87852bfd7f0
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B CORO2A SAA1 SAA2 MYH14 TRPV6	9.65e-06	168	129	6	03896466698a79f7f1ad862cb7e05585260e2a5a
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PPP4R1 GDF15 TMTC4 CARD9 ALDOC CRAMP1	1.30e-05	177	129	6	1d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCell	droplet-Fat-Gat-18m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF28 ARAP3 KANK3 ANGPTL4 SEMA6A GIMAP6	2.06e-05	192	129	6	c312e39003c51503c9f648332fb5c6218f33f99b
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	KDM5A LAMB2 CNTROB IPO9 SON ZNF292	2.06e-05	192	129	6	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	droplet-Lung-1m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARAP3 KANK3 SEMA6A CHST2 HOMER3 GIMAP6	2.06e-05	192	129	6	ff435141329e3e29fa9b08a4d5b2f55074e7f9ab
ToppCell	droplet-Fat-Gat-18m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF28 ARAP3 KANK3 ANGPTL4 SEMA6A GIMAP6	2.06e-05	192	129	6	133b3ad251d72ff31e45e1dc6217945516ac63de
ToppCell	(4)_Endothelial_cells\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	ARAP3 KANK3 ANGPTL4 SEMA6A CHST2 GIMAP6	2.12e-05	193	129	6	ae6ba13d4d9f2a700887cdda2790c32007b29ac8
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF13B TRNP1 CORO2A SPTBN2 MYH14 TRPV6	2.24e-05	195	129	6	3d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CLEC18A C12orf71 EXPH5 LIAT1 TSKS	2.62e-05	120	129	5	a6d0406a174d46ce06b41280292931954af88a59
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	ACHE KRT27 PRSS56 SPATA16 PRDM15	5.12e-05	138	129	5	8d70e64843f7c3be8ee4203cc126fdf1001f0df5
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMB2 SAA1 SAA2 GIMAP6 PLCE1	8.88e-05	155	129	5	ced64e26962c5c6e6d539f361fe57ab0b399e999
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMB2 SAA1 SAA2 GIMAP6 PLCE1	8.88e-05	155	129	5	0f24ef6486aef354f0911c06932cb01d1a0525ac
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell-Peri\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMB2 SAA1 SAA2 GIMAP6 PLCE1	8.88e-05	155	129	5	d8b5145258f075b15080f8739f537f48dd22225e
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-liver_dendritic_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CPN2 KCNG3 SAA1 SAA2 CHST2	9.15e-05	156	129	5	411c170a7dd65269ae442b8069caf5231bddb116
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TRHDE LCT CHST4 TRPV6 PLCE1	9.15e-05	156	129	5	574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TRHDE LCT CHST4 TRPV6 PLCE1	9.15e-05	156	129	5	605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDF15 CPN2 ITIH2 ANGPTL4 GPT2	9.15e-05	156	129	5	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TRHDE MYH8 ANK1 ACHE UTRN	1.06e-04	161	129	5	dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B SAA1 SAA2 MYH14 B3GNT2	1.09e-04	162	129	5	bc63a96ad3ba0b3433e3679d7a005f47709ff384
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-Pre-B\|bone_marrow / Manually curated celltypes from each tissue	FUT10 GAL3ST4 TMTC4 TECPR2 PLCE1	1.09e-04	162	129	5	e088e66aabc307dde5d2b9aa295c34ef68155b1a
ToppCell	368C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NRN1L ARHGEF28 EXPH5 CEP250 CHST2	1.16e-04	164	129	5	dd29decc6c41a580cfdf03962827ec18d432935f
ToppCell	368C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NRN1L ARHGEF28 EXPH5 CEP250 CHST2	1.16e-04	164	129	5	dcd3c3ee73900180451fad9b4de0efedbd375e1c
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGEF28 GDF15 ITIH2 SLC22A4 PLCE1	1.16e-04	164	129	5	4cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCell	PND14-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CORO2A SYNE1 CSF2RB SLC2A6 SSH2	1.16e-04	164	129	5	f4de9f18134a06f3d7fcf5b50b8e21c1506e2083
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGEF28 GDF15 ITIH2 SLC22A4 PLCE1	1.16e-04	164	129	5	7a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCell	PND14-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CORO2A SYNE1 CSF2RB SLC2A6 SSH2	1.16e-04	164	129	5	dc22b1fef49c1557a0b63c536eaba574dfcab715
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGEF28 GDF15 ITIH2 SLC22A4 PLCE1	1.16e-04	164	129	5	5e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCell	PND10-Endothelial-Endothelial_lymphatic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGEF28 GDF15 ITIH2 SLC22A4 PLCE1	1.16e-04	164	129	5	f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCell	droplet-Limb_Muscle-nan-3m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN2 GAL3ST4 TMTC4 TECPR2 ALDOC	1.23e-04	166	129	5	35db3022c33d6f8bb6587d9eec89a7cccb70271a
ToppCell	TCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Spindle_Cell-1\|TCGA-Uvea / Sample_Type by Project: Shred V9	NLRX1 LIAT1 SSH3 KANK3 KRT36	1.30e-04	168	129	5	b427746929bb40e3d1b5f1c40d302b792d6b32a5
ToppCell	E18.5-Immune-Immune_Myeloid-Granulocytic-Basophil\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SYNE1 SPTBN4 CSF2RB SLC2A6 SSH2	1.33e-04	169	129	5	b23d0aaa2da333b9c69a7aee862d5a5d2a1bf79b
ToppCell	E18.5-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SYNE1 SPTBN4 CSF2RB SLC2A6 SSH2	1.33e-04	169	129	5	83d1bcf33872b01ea9614f608a3e4ab30df25c7e
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK1 CORO2A DEPDC1 CCDC88B CSF2RB	1.37e-04	170	129	5	9e94fa0d05abed3438b28296a293767096d517d6
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_ACHE\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANK1 ACHE LRRC1 ALDOC PLCE1	1.37e-04	170	129	5	36dbbdb13f69307afd2122ff051b2980850c1f00
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122\|Adult / Lineage, Cell type, age group and donor	SYNE1 ARAP3 KANK3 SEMA6A CHST2	1.41e-04	171	129	5	bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 ARAP3 KANK3 SEMA6A GIMAP6	1.49e-04	173	129	5	f193c63cc536d891c9d23043765e320252bb6e65
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 ARAP3 KANK3 SEMA6A GIMAP6	1.49e-04	173	129	5	afa6bb19df52541d8d17cbfac9cbdd18a5f3632d
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-Alox5+_Lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDF15 SPTBN4 TBC1D31 RBM19 ATG16L2	1.53e-04	174	129	5	a8bd1fa08bf061a627529a38e5a23a68b6d80697
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDF15 SPTBN4 TBC1D31 RBM19 ATG16L2	1.53e-04	174	129	5	7f8f6a15a823809effd37c1a5b09ef19b6d67755
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMTC4 KANK3 MDC1 UTRN KRT36	1.57e-04	175	129	5	43be63976da5ad0764d24d90919a77ce46068f52
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B CKAP5 TLR8 MACF1 DMD	1.61e-04	176	129	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP43 ARAP3 KANK3 SEMA6A GIMAP6	1.70e-04	178	129	5	ba2f0585626988b511046630bc16be5c5fec3fb2
ToppCell	RA-11._Adipocyte\|RA / Chamber and Cluster_Paper	TRHDE SAA1 ANGPTL4 GPT2 MMP19	1.79e-04	180	129	5	d48a3d27357f7d184132a6805950f93080146b59
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALKBH7 LAMB2 COPG2 SEMA6A GIMAP6	1.83e-04	181	129	5	4df7972f88117108698efd06b124b232f8588981
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARAP3 KANK3 MACF1 SEMA6A UTRN	1.83e-04	181	129	5	e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D TCHP ACHE TECPR2 MMP19	1.83e-04	181	129	5	7af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALKBH7 LAMB2 COPG2 SEMA6A GIMAP6	1.83e-04	181	129	5	cbb530566893281289026bfd93adf721decd4ca3
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GDF15 ARAP3 KANK3 SEMA6A GIMAP6	1.88e-04	182	129	5	d22ab50b135482915687c70e6dad29bfe2bb2c68
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CORO2A GDF15 TBC1D31 CSF2RB CRAMP1	1.88e-04	182	129	5	57f8b8d7b132f3ad6f2b1e79c3812fe938657d2c
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK1 GDF15 SPTBN2 SAA1 SAA2	1.93e-04	183	129	5	2dde2fb48e7d31271c2f6b1dd74b2ab0b2cb520c
ToppCell	COVID-19-kidney-Mito-rich_EC\|kidney / Disease (COVID-19 only), tissue and cell type	C12orf71 SYNE1 ARAP3 KANK3 UTRN	1.93e-04	183	129	5	3c4153479fc4ab2d073d92cee120480015555914
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ARHGEF28 GDF15 EXPH5 MYH14 DMD	1.93e-04	183	129	5	c5b10571599dc26476170b54b53f09c23e6b3117
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE ANK1 DISP3 DMD PLCE1	1.98e-04	184	129	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PPP4R1 MYH14 LRRC1 UTRN PLCE1	1.98e-04	184	129	5	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE ANK1 DISP3 DMD PLCE1	1.98e-04	184	129	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE ANK1 DISP3 DMD PLCE1	1.98e-04	184	129	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PPP4R1 MYH14 LRRC1 UTRN PLCE1	1.98e-04	184	129	5	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma\|TCGA-Prostate / Sample_Type by Project: Shred V9	GDF15 SPTBN2 MEN1 TMTC4 FOLH1B	2.03e-04	185	129	5	9d53e0a92e4f99370be2e4be1dd737630796b1ca
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRNP1 SPTBN2 MYH14 ANGPTL4 TRPV6	2.03e-04	185	129	5	a6874dd3030d04380cc3c01de1069461aad4ef45
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T\|lymph-node_spleen / Manually curated celltypes from each tissue	CCHCR1 FUT10 NLRX1 CKAP5 TMEM267	2.08e-04	186	129	5	17eec1efad1f5e9ced1eb6bc9eb5dd7ded789c61
ToppCell	P28-Endothelial-unknown_endothelial_cell-endothelial_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ARAP3 SEMA6A CHST2 HOMER3 GIMAP6	2.08e-04	186	129	5	a38f84f478798951c8798c8e90e4897c729cf630
ToppCell	P28-Endothelial-unknown_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ARAP3 SEMA6A CHST2 HOMER3 GIMAP6	2.08e-04	186	129	5	dde38decf368775694bbeae38a3ff084017c34ab
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ANK1 CPN2 ITIH2 SAA1 SAA2	2.13e-04	187	129	5	edb0ab0154542b1c0b3a2c216c4a60f0f06290b3
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB2 SEMA6A GPT2 ALDOC PLCE1	2.19e-04	188	129	5	842982de2197770f999a70083ed9fca40ac22d79
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB2 SEMA6A GPT2 ALDOC PLCE1	2.19e-04	188	129	5	a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
ToppCell	RA-11._Adipocyte\|World / Chamber and Cluster_Paper	TRHDE SAA1 ANGPTL4 GPT2 MMP19	2.19e-04	188	129	5	4dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCell	facs-Heart-RA-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARAP3 KANK3 SEMA6A UTRN GIMAP6	2.24e-04	189	129	5	1be5067c1e45af7d09c1fd6955952cb9e031a3a0
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ARHGEF28 EXPH5 USP43 MYH14 DMD	2.24e-04	189	129	5	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARAP3 KANK3 SEMA6A UTRN GIMAP6	2.24e-04	189	129	5	30dc1725d43a60017fb12d706f1f85a33de4947e
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARAP3 KANK3 SEMA6A UTRN GIMAP6	2.24e-04	189	129	5	393ec5954a12d6cf67bb435dcc34ff0b14c81e9f
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ANK1 CPN2 ITIH2 SAA1 SAA2	2.24e-04	189	129	5	7899af78b273d9c7f029d52f7e0cf6df4da41f5e
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D CPXM2 GAL3ST4 PDP2 PLCE1	2.24e-04	189	129	5	4dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D CPXM2 GAL3ST4 PDP2 PLCE1	2.24e-04	189	129	5	0d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCell	facs-Heart-LV-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARAP3 KANK3 SEMA6A UTRN GIMAP6	2.24e-04	189	129	5	bec57459ad4bab15b2532b57722549fec2e771fb
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CPXM2 ITIH2 SAA2 MMP19	2.29e-04	103	129	4	39d8cfb899ca88c72ebe021d66cc21ae2eb6a1cc
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CPXM2 ITIH2 SAA2 MMP19	2.29e-04	103	129	4	01a7baaa0c3903bd00e37717856d2c1ac21bf2c8
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ANK1 CPN2 ITIH2 SAA1 SAA2	2.30e-04	190	129	5	a34293601aefe5fb5c400c14091294b9ddaa195b
ToppCell	facs-SCAT-Fat-3m-Endothelial-nan\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARAP3 CSF2RB KANK3 SEMA6A GIMAP6	2.35e-04	191	129	5	a0018f88f7132477cc467ee15db029a585290595
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC18A USP13 ANK1 CPXM2 MYH14	2.35e-04	191	129	5	543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC18A USP13 ANK1 CPXM2 MYH14	2.35e-04	191	129	5	9d7d680da3979e256191b534ebd14c5383e0cf93
ToppCell	facs-SCAT-Fat-3m-Endothelial-endothelial_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARAP3 CSF2RB KANK3 SEMA6A GIMAP6	2.35e-04	191	129	5	6b9bbf4a63d4e9a8075bb06c2aa644fcf4ee88b8
ToppCell	facs-SCAT-Fat-3m-Endothelial\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARAP3 CSF2RB KANK3 SEMA6A GIMAP6	2.35e-04	191	129	5	90f0c193dce267a4f1a9b2501f636dafd0a34cf7
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ARHGEF28 CORO2A EXPH5 USP43 DEPDC1	2.41e-04	192	129	5	25378b5e4b0cea8415ff125783511fc25a56fc00
ToppCell	droplet-Fat-Gat-18m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF28 ARAP3 KANK3 ANGPTL4 SEMA6A	2.41e-04	192	129	5	df09056f0e562f53b6fb30b674d2d83e9eb857d0
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARAP3 CSF2RB KANK3 SEMA6A CHST2	2.41e-04	192	129	5	945153c41dde6e90d103206955e1707b54eb0665
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARAP3 CSF2RB KANK3 SEMA6A CHST2	2.41e-04	192	129	5	6ab50579c63f31ca2cd41063a99b129f11c07510
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CPXM2 GDF15 EXPH5 MYH14 DMD	2.41e-04	192	129	5	c15841f35e24d6ef6ce2a9a6dc62e66efdc3d9d5
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARAP3 KANK3 SEMA6A CHST2 GIMAP6	2.41e-04	192	129	5	5012cc3ec0766f06af447463413422b484446c43
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CACNA1D ANGPTL4 MACF1 CHST2 SLC27A3	2.41e-04	192	129	5	0afb9dbe468e0be442c326e11c5fc0f699b32f23
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Radial_glial-RG\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	SPART KANK3 ANGPTL4 GPT2 ALDOC	2.41e-04	192	129	5	ee822325bb32ac7ad1eeccc23d966367e90a9edd
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRHDE ANK1 TRPV6 SEMA6A UTRN	2.47e-04	193	129	5	c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CPXM2 GDF15 EXPH5 USP43 DMD	2.47e-04	193	129	5	b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 MACF1 UTRN VPS13B ZNF292	2.47e-04	193	129	5	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRNP1 CORO2A SHROOM1 MYH14 PLCE1	2.47e-04	193	129	5	a5695ce2e24a62026ae28f3dea07ca4a435206b8
Drug	Etoposide [33419-42-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A	ANK1 GDF15 NLRX1 ITIH2 CHST4 KANK3 SLC22A4 CHST2 TSKS UTRN	7.76e-08	188	123	10	3241_UP
Drug	plakin	SYNE1 SPTBN2 SPTBN4 SPTBN5 MACF1 DMD UTRN	3.07e-07	82	123	7	CID000018752
Drug	Diprophylline [479-18-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A	KIF13B KDM5C LAMB2 MIA2 MYH14 SSH3 B3GNT2 MACF1 MMP19	1.27e-06	197	123	9	5482_DN
Drug	Ethynodiol diacetate [297-76-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A	KIF13B CACNA1D CORO2A KDM5C SPART USP19 RBM19 SSH3	1.03e-05	193	123	8	5024_DN
Drug	Thonzonium bromide [553-08-2]; Up 200; 6.8uM; MCF7; HT_HG-U133A	GDF15 KDM5C CCDC57 SPTBN5 LRRC1 SEMA6A CHST2 TSKS	1.07e-05	194	123	8	6457_UP
Drug	Clopamide [636-54-4]; Up 200; 11.6uM; PC3; HT_HG-U133A	SERHL2 CCDC57 TECPR2 MYH14 RBM19 CHST4 UTRN ZNF292	1.11e-05	195	123	8	6301_UP
Drug	dimethyl adipimidate	SPTBN2 LCT SPTBN4 SPTBN5	1.99e-05	30	123	4	CID000025738
Disease	Progressive spasticity	KDM5C GPT2	1.70e-05	2	122	2	C1859520
Disease	syndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)	KDM5A KDM5C	1.01e-04	4	122	2	DOID:0060809 (implicated_via_orthology)
Disease	spinocerebellar ataxia type 5 (implicated_via_orthology)	SPTBN2 SPTBN4	1.01e-04	4	122	2	DOID:0050882 (implicated_via_orthology)
Disease	arthrogryposis multiplex congenita (is_implicated_in)	MYH8 SYNE1	1.01e-04	4	122	2	DOID:0080954 (is_implicated_in)
Disease	alcohol use disorder (implicated_via_orthology)	KDM5A KDM5C SSH3 ANGPTL4 SSH2 HOMER3	1.65e-04	195	122	6	DOID:1574 (implicated_via_orthology)
Disease	hyperparathyroidism (is_implicated_in)	MEN1 TRPV6	1.68e-04	5	122	2	DOID:13543 (is_implicated_in)
Disease	serum amyloid A protein measurement	SAA1 SAA2	2.52e-04	6	122	2	EFO_0004728
Disease	stearoyl sphingomyelin (d18:1/18:0) measurement	KANK3 ANGPTL4	2.52e-04	6	122	2	EFO_0800611
Disease	dilated cardiomyopathy (implicated_via_orthology)	MYH8 ILK DMD YME1L1	3.45e-04	80	122	4	DOID:12930 (implicated_via_orthology)
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1D DMD UTRN	4.46e-04	36	122	3	DOID:11723 (implicated_via_orthology)
Disease	Muscular Dystrophy	ACHE DMD	4.67e-04	8	122	2	C0026850
Disease	Developmental delay (disorder)	KDM5C SPTBN2 SPART	4.84e-04	37	122	3	C0424605
Disease	syndromic intellectual disability (implicated_via_orthology)	KDM5A KDM5C	1.96e-03	16	122	2	DOID:0050888 (implicated_via_orthology)
Disease	a disintegrin and metalloproteinase with thrombospondin motifs 13 measurement	SLC2A6 PRDM15	2.21e-03	17	122	2	EFO_0008011
Disease	Global developmental delay	CACNA1B KDM5C SPTBN2 SPART	2.30e-03	133	122	4	C0557874
Disease	serum amyloid A-1 protein measurement	SAA1 SAA2	2.48e-03	18	122	2	EFO_0008282
Disease	Intellectual Disability	CACNA1B KDM5A SYNE1 KDM5C MACF1 GPT2 ZNF292	2.63e-03	447	122	7	C3714756
Disease	level of Sphingomyelin (d38:2) in blood serum	KANK3 ANGPTL4	2.77e-03	19	122	2	OBA_2045179
Disease	Sclerocystic Ovaries	CNTROB SPTBN4 TRPV6 DMD	3.06e-03	144	122	4	C1136382
Disease	Polycystic Ovary Syndrome	CNTROB SPTBN4 TRPV6 DMD	3.06e-03	144	122	4	C0032460
Disease	muscular dystrophy (implicated_via_orthology)	DMD UTRN	3.38e-03	21	122	2	DOID:9884 (implicated_via_orthology)
Disease	venous thromboembolism, plasminogen activator inhibitor 1 measurement	CKAP5 TRIM56	3.38e-03	21	122	2	EFO_0004286, EFO_0004792
Disease	free cholesterol to total lipids in large LDL percentage	KANK3 ANGPTL4 MACF1	3.61e-03	74	122	3	EFO_0022280

Protein segments in the cluster

Peptide	Gene	Start	Entry
NAARNDLWNTLSEAL	TRHDE	561	Q9UKU6
DQRLALQWVQENVAA	ACHE	206	P22303
WALNVNELRRAVQEA	GPT2	241	Q8TD30
AEDARTQRQWRTLEA	DISP3	1271	Q9P2K9
GSWDLAVQERAARSQ	CPN2	466	P22792
QQVEEWRAQNAVQRA	ATG16L2	151	Q8NAA4
QLAADIASLQNRIDW	CCDC115	146	Q96NT0
SRLAVQLRDWDGNAE	ANGPTL4	271	Q9BY76
VAEKIWSNRANRQCA	ARAP3	491	Q8WWN8
QAWEQARLREAVEAA	CCDC88B	786	A6NC98
FRVNAELQARSNIWV	AIFM1	421	O95831
LQASALNAWRGQRDN	ALDOC	306	P09972
QVTERSQDRLQDWDA	ANK1	1691	P16157
RQWQTNVDVANDLAL	DMD	2631	P11532
DWRQALRDHQEQANT	CARD9	286	Q9H257
ARQQNSAKARSVWEQ	CACNA1B	756	Q00975
AQRRAQRVAWAEADE	DDRGK1	76	Q96HY6
AGRNDLQQWIEVDAR	CPXM2	186	Q8N436
QRRAQAATWANDGLD	RBM19	141	Q9Y4C8
AQLRWQTDGEQAARI	RIMBP3B	171	A6NNM3
AQLRWQTDGEQAARI	RIMBP3C	171	A6NJZ7
WRNAAADNRSLDDRS	KCNG3	196	Q8TAE7
NRNVREALQAWADTA	MEN1	336	O00255
QQRAQATRESWLQER	ARHGEF28	1461	Q8N1W1
NNRREAEEWLAVQTE	KRT40	271	Q6A162
QASRNQRWGAVRAAE	MDC1	1751	Q14676
FNQNIRTWRNDLISA	ITIH2	351	P19823
GALREANAAAAQWRQ	HOMER3	201	Q9NSC5
ANAAAAQWRQQLEAQ	HOMER3	206	Q9NSC5
AQWRQQLEAQRAEAE	HOMER3	211	Q9NSC5
AQAQLSEWRRRQEEE	MYH14	1386	Q7Z406
QRALSKANSEVAQWR	MYH8	1361	P13535
RAALRQAFQDWSNVA	MMP19	126	Q99542
WAEDNSRLLQERGVA	FOLH1B	126	Q9HBA9
EEELNERRASTWQRN	DCAF5	571	Q96JK2
RWGSENVDDNNQLFR	DEPDC1	91	Q5TB30
ALAEQNRRDAEAWFN	KRT27	266	Q7Z3Y8
ALAEQNRRDAEAWFN	KRT25	261	Q7Z3Z0
RIWEAFANQSRAERD	LCT	361	P09848
QDWERAQQASVLANV	PPFIA1	576	Q13136
IIWNRSDSSRDRENQ	EXPH5	371	Q8NEV8
DWDRVVQDLAARTQR	LAMB2	1196	P55268
RLRANQSWEDSNTDL	GDF15	66	Q99988
EVQRNLNSWDRARVQ	NLRX1	916	Q86UT6
EDRQLTARARAWNNL	GAL3ST4	351	Q96RP7
IQDNVRRQSSRVSWA	SLC2A6	251	Q9UGQ3
WQDRARQALATDELS	KDM5A	1256	P29375
DVSDEAWNERAVNRV	LRRC1	441	Q9BTT6
RDAWQDNALRIAEQE	MACF1	1081	Q9UPN3
TRDHNAWNQAELSRL	PDP2	306	Q9P2J9
NVRAAALATVNAWAE	CKAP5	956	Q14008
RWADTQDAQRLVNVT	CSF2RB	46	P32927
ALRWLVDRNQNFSSQ	FUT10	456	Q6P4F1
QQLRASLWAQEAKAA	CEP250	1136	Q9BV73
NNRQVALWDQDNLSV	CORO2A	246	Q92828
ASRLAQQLREEGWNL	CRAMP1	666	Q96RY5
GNAVAVRLWLDNTEN	ILK	11	Q13418
TLEAQLRRAEWRQAD	CCDC57	326	Q2TAC2
AQEARRRWQQQTASA	CCHCR1	411	Q8TD31
RRWQQQTASAEEQLR	CCHCR1	416	Q8TD31
RWINEAQEAASSDNI	COPG2	176	Q9UBF2
RDGRVDSWRNFQANT	DNAJC8	216	O75937
ANAARQATPAEWSQD	IPO9	931	Q96P70
QEWFRVSSQRRSQAE	KANK3	581	Q6NY19
GQTQDWDQERRADRQ	HELZ2	2046	Q9BYK8
VQQAGQLARRLWEAS	HPS1	681	Q92902
EWIGLIRAARNSQEQ	PRDM13	66	Q9H4Q3
LVLNRDQRLAWAENS	SERHL2	206	Q9H4I8
RVPDAANLSSAWRNN	SLC22A4	51	Q9H015
LSWQAAIDAARQAKA	CACNA1D	51	Q01668
LRAALEEERQTWAQQ	CNTROB	351	Q8N137
ALVENNRRDVEAWFN	KRT36	271	O76013
ALQAAQRSAQWAINR	PRSS56	41	P0CW18
NWLAARNAERNLNDL	MIA2	1071	Q96PC5
AAAVWESLQQEARQA	NRN1L	91	Q496H8
QRLRQWAEEREATLN	KIF13B	666	Q9NQT8
NALEAEWRTVQASRR	UTRN	2436	P46939
NRRAVEWDTTGQNLI	TBC1D31	1026	Q96DN5
DNSRNWRFRAELAEQ	PPP4R1	751	Q8TF05
WAAEVISNARENIQR	SAA2	71	P0DJI9
QAEDRALESLRQDWQ	SYNE1	3566	Q8NF91
NNQALAWLDVTLARR	GIMAP6	181	Q6P9H5
NLANRINESLRWDGI	LIAT1	161	Q6ZQX7
EIRQDGSQRLSEAQW	PLCE1	386	Q9P212
AQLRWQTDGEQAARI	RIMBP3	171	Q9UFD9
AFREAESWSQIGNQR	PRDM15	131	P57071
AQAWARRQAALEAAV	SHROOM1	676	Q2M3G4
AAWLLREAAQTQAEN	CCT8L1P	86	A6NM43
AAWLLREAGQTQAEN	CCT8L2	86	Q96SF2
DTLEGRRNNNERVWN	SPATA16	511	Q9BXB7
WAVQNIRNVLVDASA	HERC2P3	466	Q9BVR0
ANDRNDRAIRVAAKW	DIS3	141	Q9Y2L1
ASWAARVRQDLQVEE	SPTBN5	1956	Q9NRC6
QRSRIEAAWERLDQA	SPTBN5	3186	Q9NRC6
QNSSEENRLFTQRWR	SPICE1	591	Q8N0Z3
WAAEAISDARENIQR	SAA1	71	P0DJI8
EWNAANLEELQRNRV	SSH3	341	Q8TE77
ARRQAIRESWGQESN	B3GNT2	156	Q9NY97
WSEASRAILQRVQAA	ALKBH7	81	Q9BT30
VSARNATQAANAWRT	CHST2	471	Q9Y4C5
HTNARDALNVSQAWR	CHST4	321	Q8NCG5
TDSRANRLLNGDNLW	C12orf71	101	A8MTZ7
RLDWSDSLAQLAQAR	CLEC18A	71	A5D8T8
RLDWSDSLAQLAQAR	CLEC18B	71	Q6UXF7
RLDWSDSLAQLAQAR	CLEC18C	71	Q8NCF0
ANWDQSRNSFTDILR	CLVS1	146	Q8IUQ0
DGDLSSWINRERFQN	TMX3	216	Q96JJ7
DLNRHVDALNAWRNA	TMTC4	596	Q5T4D3
SGNRLDILWNDDDNR	TLR8	616	Q9NR97
SAFDDAIIQRQWRAN	STK19	6	P49842
SDLRLQANWNRAEEE	SPART	331	Q8N0X7
AAEAAASQASRIWQE	USP19	1236	O94966
IREDRAVSWAQLQQS	USP43	421	Q70EL4
SQASARAAELQAQWE	SPTBN2	716	O15020
WNASNLEDLQNRGVR	SSH2	321	Q76I76
SAVAELRARWGLQDN	RP1L1	1536	Q8IWN7
SLAWRLAELAQQRAA	SLC27A3	66	Q5K4L6
SRGSREWERNQNLIN	SEMA6A	771	Q9H2E6
NNIENSLLADRSDAW	ZNF292	876	O60281
RESWAQSRDEQNLLQ	TRPV6	66	Q9H1D0
RESWLNENQRLVSQD	SPTBN4	441	Q9H254
VAERRLQAWEADQQE	TCHP	441	Q9BT92
TARNNVVWALTEQRA	TECPR2	941	O15040
LGQWERAQREQAQTA	TSKS	366	Q9UJT2
SLALAWNRVDIARSQ	TRPM1	376	Q7Z4N2
ENDRWNETRAQLLAQ	YME1L1	636	Q96TA2
WRIVLNSSQNGADDQ	VPS13B	2426	Q7Z7G8
SAGAAEDQELQRWRQ	TRNP1	61	Q6NT89
NRAQERIDAWAQLNS	SON	2251	P18583
TIQQNDWLRALSDNA	TMEM267	41	Q0VDI3
RATNNNLERALDWIF	USP13	751	Q92995
QIDGQTWAERALREN	TMEM25	31	Q86YD3
NGEVQWRRALSLSQA	TRIM56	576	Q9BRZ2
ISWQGRARQALASED	KDM5C	1286	P41229