Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	microtubule motor activity	DNAH12 KIF3B DNAH2 KIF3C KIF7	1.43e-05	70	88	5	GO:0003777
GeneOntologyMolecularFunction	A-type (transient outward) potassium channel activity	KCND1 KCND3	1.15e-04	4	88	2	GO:0005250
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNAH12 KIF3B DNAH2 KIF3C KIF7	1.75e-04	118	88	5	GO:0003774
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ABCA4 ABCA12 ATP10D	2.50e-04	28	88	3	GO:0140326
GeneOntologyBiologicalProcess	sodium ion import across plasma membrane	SLC8A1 SLC9C1 SLC9A2 SLC5A6	4.81e-06	27	87	4	GO:0098719
GeneOntologyCellularComponent	microtubule	LRPPRC SLC8A1 DNAH12 KIF3B EML5 LRRC49 DNAH2 ASPM DYRK1A KIF3C KIF7	1.45e-05	533	88	11	GO:0005874
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	LRPPRC SLC8A1 DNAH12 KIF3B EML5 INF2 LRRC49 DNAH2 ASPM DYRK1A KIF3C KIF7	3.77e-04	899	88	12	GO:0099513
GeneOntologyCellularComponent	fibrinogen complex	FN1 FGG	4.83e-04	8	88	2	GO:0005577
GeneOntologyCellularComponent	microtubule associated complex	DNAH12 KIF3B DNAH2 KIF3C KIF7	5.96e-04	161	88	5	GO:0005875
GeneOntologyCellularComponent	inner dynein arm	DNAH12 DNAH2	7.71e-04	10	88	2	GO:0036156
GeneOntologyCellularComponent	Golgi membrane	XYLT1 VAC14 WIPI1 MGAT2 B4GALNT1 ABCA12 B4GALNT2 STING1 HUWE1 CHST8	8.94e-04	721	88	10	GO:0000139
GeneOntologyCellularComponent	ciliary tip	KIF3B KIF3C KIF7	1.09e-03	48	88	3	GO:0097542
GeneOntologyCellularComponent	kinesin complex	KIF3B KIF3C KIF7	1.15e-03	49	88	3	GO:0005871
Domain	GM2_synthase	B4GALNT1 B4GALNT2	2.05e-05	2	85	2	IPR011143
Domain	DUF3399	KCND1 KCND3	6.12e-05	3	85	2	PF11879
Domain	K_chnl_volt-dep_Kv4	KCND1 KCND3	6.12e-05	3	85	2	IPR003975
Domain	Shal-type	KCND1 KCND3	6.12e-05	3	85	2	PF11601
Domain	Shal-type_N	KCND1 KCND3	6.12e-05	3	85	2	IPR021645
Domain	K_chnl_volt-dep_Kv4_C	KCND1 KCND3	6.12e-05	3	85	2	IPR024587
Domain	Kinesin_motor_CS	KIF3B KIF3C KIF7	8.56e-04	41	85	3	IPR019821
Domain	Kinesin-like_fam	KIF3B KIF3C KIF7	9.84e-04	43	85	3	IPR027640
Domain	KINESIN_MOTOR_1	KIF3B KIF3C KIF7	1.05e-03	44	85	3	PS00411
Domain	-	KIF3B KIF3C KIF7	1.05e-03	44	85	3	3.40.850.10
Domain	Kinesin_motor_dom	KIF3B KIF3C KIF7	1.05e-03	44	85	3	IPR001752
Domain	Kinesin	KIF3B KIF3C KIF7	1.05e-03	44	85	3	PF00225
Domain	KINESIN_MOTOR_2	KIF3B KIF3C KIF7	1.05e-03	44	85	3	PS50067
Domain	KISc	KIF3B KIF3C KIF7	1.05e-03	44	85	3	SM00129
Domain	Cation/H_exchanger_CPA1	SLC9C1 SLC9A2	1.10e-03	11	85	2	IPR018422
Domain	ABC_A	ABCA4 ABCA12	1.31e-03	12	85	2	IPR026082
Domain	P-loop_NTPase	TANC2 ABCA4 SETX DNAH12 KIF3B ABCA12 DNAH2 ASPM GNAI2 KIF3C KIF7	1.57e-03	848	85	11	IPR027417
Domain	Na_H_Exchanger	SLC9C1 SLC9A2	1.80e-03	14	85	2	PF00999
Domain	Dynein_heavy_chain_D4_dom	DNAH12 DNAH2	1.80e-03	14	85	2	IPR024317
Domain	Dynein_heavy_dom-2	DNAH12 DNAH2	1.80e-03	14	85	2	IPR013602
Domain	DHC_N2	DNAH12 DNAH2	1.80e-03	14	85	2	PF08393
Domain	Cation/H_exchanger	SLC9C1 SLC9A2	1.80e-03	14	85	2	IPR006153
Domain	AAA_8	DNAH12 DNAH2	1.80e-03	14	85	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH12 DNAH2	1.80e-03	14	85	2	IPR011704
Domain	AAA_5	DNAH12 DNAH2	1.80e-03	14	85	2	PF07728
Domain	p53-like_TF_DNA-bd	TBX4 NFATC2 STAT3	1.81e-03	53	85	3	IPR008967
Domain	DHC_fam	DNAH12 DNAH2	2.07e-03	15	85	2	IPR026983
Domain	Dynein_heavy_dom	DNAH12 DNAH2	2.07e-03	15	85	2	IPR004273
Domain	Dynein_heavy	DNAH12 DNAH2	2.07e-03	15	85	2	PF03028
Domain	AAA+_ATPase	ABCA4 DNAH12 ABCA12 DNAH2	4.23e-03	144	85	4	IPR003593
Domain	AAA	ABCA4 DNAH12 ABCA12 DNAH2	4.23e-03	144	85	4	SM00382
Domain	ARM-type_fold	VAC14 INF2 DOCK11 PKP4 ASPM HUWE1	4.50e-03	339	85	6	IPR016024
Pubmed	Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling.	NCF1C NCF1B STAT3	3.11e-07	6	88	3	33349630
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TANC2 PHF2 PRKD2 FAT1 TUT4 EML5 ABCA12 PKP4 GRAP2 ASPM ZFHX3 TRIM27 WDR13 KIF7	7.98e-07	1116	88	14	31753913
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	XYLT1 SETX NFATC2 NUP133 DYRK1A ZBTB40 CCAR2 HUWE1 TRIM27 PRDM6 STAT3 KIF7	1.71e-06	857	88	12	25609649
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TANC2 DZANK1 LRPPRC KIF3B NEDD4L DOCK11 PKP4 DYRK1A TJAP1 CCAR2 HUWE1 KIF7	5.64e-06	963	88	12	28671696
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	TANC2 DZANK1 LRPPRC SLC9C1 KIF3B EML5 PDE9A NUP133 DYRK1A CDH23 CCAR2 KIF3C EXOC8 KIF7	5.65e-06	1321	88	14	27173435
Pubmed	Sensory Detection by the Vomeronasal Organ Modulates Experience-Dependent Social Behaviors in Female Mice.	GNAI2 OMP	6.33e-06	2	88	2	33679330
Pubmed	Renalase Expression by Melanoma and Tumor-Associated Macrophages Promotes Tumor Growth through a STAT3-Mediated Mechanism.	RNLS STAT3	6.33e-06	2	88	2	27197188
Pubmed	The fibronectin-binding MSCRAMM FnbpA of Staphylococcus aureus is a bifunctional protein that also binds to fibrinogen.	FN1 FGG	6.33e-06	2	88	2	10788510
Pubmed	Functional pseudogenes inhibit the superoxide production.	NCF1C NCF1B	6.33e-06	2	88	2	26086043
Pubmed	Fucose and sialic acid expressions in human seminal fibronectin and α{1} -acid glycoprotein associated with leukocytospermia of infertile men.	ORM1 FN1	6.33e-06	2	88	2	22048274
Pubmed	circFAT1 Promotes Cancer Stemness and Immune Evasion by Promoting STAT3 Activation.	FAT1 STAT3	6.33e-06	2	88	2	34258151
Pubmed	Paeoniflorin Regulates NEDD4L/STAT3 Pathway to Induce Ferroptosis in Human Glioma Cells.	NEDD4L STAT3	6.33e-06	2	88	2	36618071
Pubmed	Gαi2+ vomeronasal neurons govern the initial outcome of an acute social competition.	GNAI2 OMP	6.33e-06	2	88	2	31965032
Pubmed	Targeting of p0071 to the midbody depends on KIF3.	KIF3B PKP4	6.33e-06	2	88	2	19339549
Pubmed	Genetic predictors of fibrin D-dimer levels in healthy adults.	ABCA4 PROCR FGG	8.56e-06	16	88	3	21502573
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	TUT4 FN1 PDE9A NUP133 TJAP1 CCAR2 USPL1 TRIM27 KIF7	1.26e-05	560	88	9	21653829
Pubmed	Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development.	COL12A1 TBX4 FN1	1.73e-05	20	88	3	29084951
Pubmed	Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.	NCF1C NCF1B	1.90e-05	3	88	2	27044504
Pubmed	NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.	NCF1C NCF1B	1.90e-05	3	88	2	18787174
Pubmed	Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.	NCF1C NCF1B	1.90e-05	3	88	2	24873968
Pubmed	p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.	NCF1C NCF1B	1.90e-05	3	88	2	22184329
Pubmed	Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis.	NCF1C NCF1B	1.90e-05	3	88	2	33545139
Pubmed	Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.	NCF1C NCF1B	1.90e-05	3	88	2	20142487
Pubmed	DYRK1A inhibition suppresses STAT3/EGFR/Met signalling and sensitizes EGFR wild-type NSCLC cells to AZD9291.	DYRK1A STAT3	1.90e-05	3	88	2	31454149
Pubmed	p47(phox) contributes to albuminuria and kidney fibrosis in mice.	NCF1C NCF1B	1.90e-05	3	88	2	25565313
Pubmed	Epithelial to mesenchymal transition promotes breast cancer progression via a fibronectin-dependent STAT3 signaling pathway.	FN1 STAT3	1.90e-05	3	88	2	23653350
Pubmed	Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.	NCF1C NCF1B	1.90e-05	3	88	2	39357591
Pubmed	Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells.	NCF1C NCF1B	1.90e-05	3	88	2	11435342
Pubmed	Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8+ T Cell Activation via Cross-Presentation in Type 1 Diabetes.	NCF1C NCF1B	1.90e-05	3	88	2	31118934
Pubmed	Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice.	NCF1C NCF1B	1.90e-05	3	88	2	16041040
Pubmed	Kinesin-2 KIF3AC and KIF3AB Can Drive Long-Range Transport along Microtubules.	KIF3B KIF3C	1.90e-05	3	88	2	26445448
Pubmed	Intermittent hypoxia has organ-specific effects on oxidative stress.	NCF1C NCF1B	1.90e-05	3	88	2	18703411
Pubmed	Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run.	KIF3B KIF3C	1.90e-05	3	88	2	27637334
Pubmed	Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion.	NCF1C NCF1B	1.90e-05	3	88	2	17307863
Pubmed	Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.	NCF1C NCF1B	1.90e-05	3	88	2	27829407
Pubmed	The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.	NCF1C NCF1B	1.90e-05	3	88	2	22376231
Pubmed	Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.	NCF1C NCF1B	1.90e-05	3	88	2	23918780
Pubmed	NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells.	NCF1C NCF1B	1.90e-05	3	88	2	28274989
Pubmed	Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.	NCF1C NCF1B	1.90e-05	3	88	2	12364355
Pubmed	NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities.	NCF1C NCF1B	1.90e-05	3	88	2	34557202
Pubmed	Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.	NCF1C NCF1B	1.90e-05	3	88	2	28467721
Pubmed	P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+.	NCF1C NCF1B	1.90e-05	3	88	2	10670582
Pubmed	Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.	NCF1C NCF1B	1.90e-05	3	88	2	26528554
Pubmed	The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis.	NCF1C NCF1B	1.90e-05	3	88	2	19052348
Pubmed	Effect of early particulate air pollution exposure on obesity in mice: role of p47phox.	NCF1C NCF1B	1.90e-05	3	88	2	20864666
Pubmed	Reactive oxygen species delay control of lymphocytic choriomeningitis virus.	NCF1C NCF1B	1.90e-05	3	88	2	23328631
Pubmed	p47phox-Dependent Oxidant Signalling through ASK1, MKK3/6 and MAPKs in Angiotensin II-Induced Cardiac Hypertrophy and Apoptosis.	NCF1C NCF1B	1.90e-05	3	88	2	34572995
Pubmed	Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.	NCF1C NCF1B	1.90e-05	3	88	2	17114280
Pubmed	B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.	NCF1C NCF1B	1.90e-05	3	88	2	25989352
Pubmed	Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase.	NCF1C NCF1B	1.90e-05	3	88	2	17404617
Pubmed	Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction.	NCF1C NCF1B	1.90e-05	3	88	2	17332431
Pubmed	Lpp of Escherichia coli K1 inhibits host ROS production to counteract neutrophil-mediated elimination.	NCF1C NCF1B	1.90e-05	3	88	2	36592568
Pubmed	Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression.	NCF1C NCF1B	1.90e-05	3	88	2	30504842
Pubmed	Direct interaction of HIV gp120 with neuronal CXCR4 and CCR5 receptors induces cofilin-actin rod pathology via a cellular prion protein- and NOX-dependent mechanism.	NCF1C NCF1B	1.90e-05	3	88	2	33705493
Pubmed	DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3.	DYRK1A STAT3	1.90e-05	3	88	2	33393494
Pubmed	Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis.	NCF1C NCF1B	1.90e-05	3	88	2	23965970
Pubmed	Expression of KIF3C kinesin during neural development and in vitro neuronal differentiation.	KIF3B KIF3C	1.90e-05	3	88	2	11331403
Pubmed	Unique clustering of A-type potassium channels on different cell types of the main olfactory bulb.	KCND1 KCND3	1.90e-05	3	88	2	18371079
Pubmed	Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice.	NCF1C NCF1B	1.90e-05	3	88	2	15513930
Pubmed	Phosphoinositide 3-kinase regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling cPKC/PKCdelta but not Akt.	NCF1C NCF1B	1.90e-05	3	88	2	15033459
Pubmed	Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles.	NCF1C NCF1B	1.90e-05	3	88	2	20828610
Pubmed	p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation.	NCF1C NCF1B	1.90e-05	3	88	2	20817944
Pubmed	NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions.	NCF1C NCF1B	1.90e-05	3	88	2	36853827
Pubmed	Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation.	NCF1C NCF1B	1.90e-05	3	88	2	23024271
Pubmed	Ncf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells.	NCF1C NCF1B	1.90e-05	3	88	2	21253614
Pubmed	Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene.	NCF1C NCF1B	1.90e-05	3	88	2	15310853
Pubmed	ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3.	ZFHX3 STAT3	1.90e-05	3	88	2	14715251
Pubmed	Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21.	NCF1C NCF1B	1.90e-05	3	88	2	31393787
Pubmed	Vascular effects following homozygous disruption of p47(phox) : An essential component of NADPH oxidase.	NCF1C NCF1B	1.90e-05	3	88	2	10725280
Pubmed	Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice.	NCF1C NCF1B	1.90e-05	3	88	2	34970267
Pubmed	Germ-free mice deficient of reactive oxygen species have increased arthritis susceptibility.	NCF1C NCF1B	1.90e-05	3	88	2	25689796
Pubmed	Down-regulation of ATBF1 activates STAT3 signaling via PIAS3 in pacing-induced HL-1 atrial myocytes.	ZFHX3 STAT3	1.90e-05	3	88	2	24857987
Pubmed	Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation.	NCF1C NCF1B	1.90e-05	3	88	2	14993144
Pubmed	Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation.	NCF1C NCF1B	1.90e-05	3	88	2	22050439
Pubmed	The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.	NCF1C NCF1B	1.90e-05	3	88	2	12031896
Pubmed	NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion.	NCF1C NCF1B	1.90e-05	3	88	2	11249873
Pubmed	Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice.	NCF1C NCF1B	1.90e-05	3	88	2	15936744
Pubmed	NADPH oxidase p47phox siRNA attenuates adventitial fibroblasts proliferation and migration in apoE(-/-) mouse.	NCF1C NCF1B	1.90e-05	3	88	2	25628043
Pubmed	Plasma proteomics analysis of adolescent idiopathic scoliosis patients revealed by Quadrupole-Orbitrap mass spectrometry.	FN1 FGG	1.90e-05	3	88	2	33864425
Pubmed	Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. Role of the p47phox subunit.	NCF1C NCF1B	1.90e-05	3	88	2	12560337
Pubmed	Inhibition of endothelial Nox2 activation by LMH001 protects mice from angiotensin II-induced vascular oxidative stress, hypertension and aortic aneurysm.	NCF1C NCF1B	1.90e-05	3	88	2	35276443
Pubmed	Reactive oxygen species modulate growth of cerebral aneurysms: a study using the free radical scavenger edaravone and p47phox(-/-) mice.	NCF1C NCF1B	1.90e-05	3	88	2	19381132
Pubmed	Identification of a novel NCF-1 (p47-phox) pseudogene not containing the signature GT deletion: significance for A47 degrees chronic granulomatous disease carrier detection.	NCF1C NCF1B	1.90e-05	3	88	2	12176908
Pubmed	A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease.	NCF1C NCF1B	1.90e-05	3	88	2	9329953
Pubmed	Superoxide prevents nitric oxide-mediated suppression of helper T lymphocytes: decreased autoimmune encephalomyelitis in nicotinamide adenine dinucleotide phosphate oxidase knockout mice.	NCF1C NCF1B	1.90e-05	3	88	2	10799876
Pubmed	Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-alpha.	NCF1C NCF1B	1.90e-05	3	88	2	11834706
Pubmed	A model of chronic enthesitis and new bone formation characterized by multimodal imaging.	NCF1C NCF1B	1.90e-05	3	88	2	30045841
Pubmed	Virulence and cellular interactions of Burkholderia multivorans in chronic granulomatous disease.	NCF1C NCF1B	1.90e-05	3	88	2	19635825
Pubmed	The NCF1 variant p.R90H aggravates autoimmunity by facilitating the activation of plasmacytoid dendritic cells.	NCF1C NCF1B	1.90e-05	3	88	2	35788118
Pubmed	Hydrophobic bile salts induce hepatocyte shrinkage via NADPH oxidase activation.	NCF1C NCF1B	1.90e-05	3	88	2	17310103
Pubmed	Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia.	NCF1C NCF1B	1.90e-05	3	88	2	18036262
Pubmed	Transient loss of resistance to pulmonary tuberculosis in p47(phox-/-) mice.	NCF1C NCF1B	1.90e-05	3	88	2	10678931
Pubmed	Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.	NCF1C NCF1B	1.90e-05	3	88	2	17167081
Pubmed	Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.	NCF1C NCF1B	1.90e-05	3	88	2	24358335
Pubmed	Molecular characterization of the mouse p47-phox (Ncf1) gene and comparative analysis of the mouse p47-phox (Ncf1) gene to the human NCF1 gene.	NCF1C NCF1B	1.90e-05	3	88	2	10891396
Pubmed	P47phox-/- mice are compromised in expansion and activation of CD8+ T cells and susceptible to Trypanosoma cruzi infection.	NCF1C NCF1B	1.90e-05	3	88	2	25474113
Pubmed	NAD(P)H oxidase subunit p47phox is elevated, and p47phox knockout prevents diaphragm contractile dysfunction in heart failure.	NCF1C NCF1B	1.90e-05	3	88	2	26209274
Pubmed	NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.	NCF1C NCF1B	1.90e-05	3	88	2	11018074
Pubmed	Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease.	NCF1C NCF1B	1.90e-05	3	88	2	9116268
Pubmed	Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.	NCF1C NCF1B	1.90e-05	3	88	2	20686129
Interaction	EEF1AKMT3 interactions	PRKD2 VAC14 SETX WASHC4 TBC1D2B CCAR2 HUWE1 USP48 XAB2 STAT3	3.80e-06	364	87	10	int:EEF1AKMT3
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF3B KIF3C KIF7	6.59e-04	46	67	3	622
GeneFamily	ATP binding cassette subfamily A	ABCA4 ABCA12	1.20e-03	14	67	2	805
GeneFamily	Dyneins, axonemal	DNAH12 DNAH2	1.77e-03	17	67	2	536
GeneFamily	Cadherin related	FAT1 CDH23	1.77e-03	17	67	2	24
GeneFamily	Beta 4-glycosyltransferases	B4GALNT1 B4GALNT2	1.77e-03	17	67	2	425
GeneFamily	Cyclins	CCNG2 CCNYL2	4.81e-03	28	67	2	473
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FAT1 COL12A1 TBX4 FN1 NFATC2 PRDM6	1.66e-06	182	88	6	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC8A1 FAT1 COL12A1 ABCA4 ABCA12 LRP1B	1.77e-06	184	88	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC8A1 FAT1 COL12A1 ABCA4 ABCA12 LRP1B	1.77e-06	184	88	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC8A1 FAT1 COL12A1 ABCA4 ABCA12 LRP1B	1.77e-06	184	88	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-D\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	WIPI1 PROCR TMC6 NCF1C NCF1B MEPE	2.20e-06	191	88	6	7d00796459f4ff0ab7f06a8379b2d34e76b078b2
ToppCell	facs-Large_Intestine-Proximal\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC8A1 SLC9A2 B4GALNT1 ABCA12 B4GALNT2	2.09e-05	168	88	5	23e0e1592d7400012d289adb10c7598285bae2e9
ToppCell	facs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYRIA IGSF6 B4GALNT1 TMC6 TBC1D2B	2.09e-05	168	88	5	c0aef5947b1d7e2c81a7481c509feda1687fcd7f
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC8A1 SLC9A2 B4GALNT1 ABCA12 B4GALNT2	2.40e-05	173	88	5	e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCell	facs-Large_Intestine-Proximal-3m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC8A1 SLC9A2 B4GALNT1 ABCA12 B4GALNT2	2.40e-05	173	88	5	99532bb768ee35fed939a377acb5215d3f8904bd
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CCNG2 SLC9A2 COL12A1 PDE9A VWA5B1	2.54e-05	175	88	5	e78bf0c33a741bb97e987e41ac33da9e623a08ec
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	XYLT1 COL12A1 FN1 NFATC2 ATP10D	2.61e-05	176	88	5	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	XYLT1 COL12A1 FN1 NFATC2 ATP10D	2.61e-05	176	88	5	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCNG2 SLC8A1 SLC9A2 ABCA12 B4GALNT2	2.61e-05	176	88	5	7622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 SETX EML5 NFATC2 GRAP2	2.75e-05	178	88	5	a9a8567d8fdc0fffd612fee16b5b29ef7b1c9307
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 SETX EML5 NFATC2 GRAP2	2.75e-05	178	88	5	5ecbea15efd304057aef826ec2f385997bfaf0c9
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	DZANK1 VAC14 NEDD4L NUP133 WDR13	3.14e-05	183	88	5	3cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 SLC8A1 SLC9A2 NEDD4L VWA5B1	3.31e-05	185	88	5	3d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FAT1 COL12A1 TBX4 FN1 PRDM6	3.48e-05	187	88	5	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	FAT1 COL12A1 TBX4 FN1 PRDM6	3.66e-05	189	88	5	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9C1 SLC9A2 NEDD4L B4GALNT2 VWA5B1	3.66e-05	189	88	5	532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CCNG2 DZANK1 CYRIA SLC5A6 TMC6	3.76e-05	190	88	5	ed100e271aac82806f59e0c613ccda63f59100c1
ToppCell	Monocytes-Tissue-resident_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	TANC2 SLC8A1 IGSF6 FN1 ZFHX3	3.76e-05	190	88	5	07215e8f292cb54c670037aaf28393cddbe5548c
ToppCell	IPF-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	XYLT1 CYRIA SLC8A1 CDH23 BID	3.76e-05	190	88	5	f9c2a13c7f6460e3b348581be855b7281c8f70b5
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9C1 SLC9A2 PDE9A LRP1B VWA5B1	3.85e-05	191	88	5	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	TANC2 XYLT1 CYRIA SLC8A1 DOCK11	3.85e-05	191	88	5	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TBX4 FN1 ENPEP PRDM6 CHST8	3.85e-05	191	88	5	beb5bb42bd53bce01339da9110d374901548793c
ToppCell	(2)_Fibroblasts-(21)_Fibro-2\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CYRIA FN1 PROCR CDH23 ECEL1	3.85e-05	191	88	5	5ee353c79055c08e8a3e2b43a0345bceb09f3890
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TBX4 FN1 ENPEP PRDM6 CHST8	3.85e-05	191	88	5	6609d85fd2577633dcc067507304a6f9e5865ca3
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC8A1 FAT1 TBX4 ZFHX3 PRDM6	3.95e-05	192	88	5	992d08092edbc68c47b945deb8708379738c239a
ToppCell	IPF-Myeloid-ncMonocyte\|IPF / Disease state, Lineage and Cell class	XYLT1 CYRIA SLC8A1 CDH23 BID	3.95e-05	192	88	5	e9fb8c57d8094f70fb492909b2bec40aa5f2e5b8
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CYRIA SLC8A1 IGSF6 CDH23 BID	3.95e-05	192	88	5	7bcdbd97fa8c3bfccde426d44979601226913fc3
ToppCell	3'_v3-bone_marrow-Myeloid_Monocytic-Nonclassical_monocytes\|bone_marrow / Manually curated celltypes from each tissue	CYRIA SLC8A1 IGSF6 CDH23 BID	4.05e-05	193	88	5	dc309c249d569e93dc2b154e002212a6eee44497
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX4 FN1 ENPEP PRDM6 CHST8	4.05e-05	193	88	5	fa45042d30f9cfeed10e23270a78f18551219cfa
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	COL12A1 FN1 NFATC2 ECEL1 STING1	4.05e-05	193	88	5	e1de67ddada87229f5db0ec193a6da8745a86a64
ToppCell	LA\|World / Chamber and Cluster_Paper	XYLT1 COL12A1 FN1 ZFHX3 LRP1B	4.05e-05	193	88	5	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal-choroid_plexus/mesenchymal-like_cells\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	COL12A1 FN1 NFATC2 ECEL1 STING1	4.05e-05	193	88	5	b6f5a85210e60798205eaf5884cdb540f549d08a
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX4 FN1 ENPEP PRDM6 CHST8	4.05e-05	193	88	5	ab511ea9e09216a965b3ae5a94f8c3c1ae33d944
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FAT1 TBX4 ZFHX3 PRDM6 MEPE	4.05e-05	193	88	5	e2b455387d1de7812305200a2041a0f4759a6f54
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 SLC8A1 FAT1 SLC9A2 LRP1B	4.15e-05	194	88	5	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	nucseq-Immune-Immune_Myeloid-pMON-pMON\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	XYLT1 CYRIA SLC8A1 CDH23 BID	4.15e-05	194	88	5	e237384b02be460d44eeada3026a5691c66f6fc1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 SLC8A1 FAT1 SLC9A2 LRP1B	4.15e-05	194	88	5	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	nucseq-Immune-Immune_Myeloid-pMON\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	XYLT1 CYRIA SLC8A1 CDH23 BID	4.15e-05	194	88	5	0bc83ae79873a5e473e6e1e3111924cd003986a1
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.25e-05	195	88	5	157f1f9b0521c9eba11806eb4b6802ff116ab912
ToppCell	Adult-Immune-monocyte-D231\|Adult / Lineage, Cell type, age group and donor	XYLT1 CYRIA SLC8A1 CDH23 BID	4.25e-05	195	88	5	ea24da6fea1487acb1e56c28c0649858cc0a12bd
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	TANC2 XYLT1 CYRIA SLC8A1 DOCK11	4.25e-05	195	88	5	ba7f85e5307d96ac5ad7c952f8d094db9ca1790c
ToppCell	mild_COVID-19_(asymptomatic)-Non-classical_Monocyte\|World / disease group, cell group and cell class (v2)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.25e-05	195	88	5	eb809331557f8c40de45b1208cbc49b621930a4b
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Nonclassical_Monocyte\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.25e-05	195	88	5	95327f2818bcdca53dbd2971f674a9042a1392c6
ToppCell	Control-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	XYLT1 CYRIA SLC8A1 CDH23 BID	4.25e-05	195	88	5	b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCell	Adult-Immune-monocyte\|Adult / Lineage, Cell type, age group and donor	XYLT1 CYRIA SLC8A1 CDH23 BID	4.36e-05	196	88	5	3ef193c5180de3137daf886492e74fc574bc9767
ToppCell	Mild_COVID-19-Myeloid-MoAM3\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	SLC8A1 IGSF6 FN1 ANXA4 MEPE	4.36e-05	196	88	5	9faad17aa0b6af5a8ec2dadf7d70b9209d658072
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.36e-05	196	88	5	29246378ffb1010fe6858da756ae3d13df2306ba
ToppCell	myeloid-Monocyte-CD16+_Monocyte\|World / Lineage, cell class and subclass	CYRIA SLC8A1 IGSF6 CDH23 BID	4.46e-05	197	88	5	a50007ec22259b748e47dee637867e2cf41e65db
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.46e-05	197	88	5	083fec147040ee0bebac2815fb89355cf3a7ffa5
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.46e-05	197	88	5	f0e6745b0fd734ea17e7a2a883e48017e8d3102d
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.46e-05	197	88	5	b82142cf8057a55dfa884248b752173661edffd1
ToppCell	COVID-19_Severe-Myeloid-Non-classical_Monocyte\|COVID-19_Severe / Disease group, lineage and cell class	CYRIA SLC8A1 IGSF6 CDH23 BID	4.46e-05	197	88	5	c5837b9a5a39a0f607a4e217ade9fc87d82a5406
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.46e-05	197	88	5	96d56bce69de7192c7a6b43371b56f4acdcc7733
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.46e-05	197	88	5	70faaea9c143337a52c8f660ebb063aa92327357
ToppCell	10x5'-bone_marrow-Myeloid_Monocytic-Nonclassical_monocytes\|bone_marrow / Manually curated celltypes from each tissue	CYRIA SLC8A1 IGSF6 CDH23 BID	4.46e-05	197	88	5	dcf1e74b7c21466d38d68f44d404bce14ade2805
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.46e-05	197	88	5	422074930fce25a6ad15ba41e391c65787e7878e
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	XYLT1 CYRIA SLC8A1 IGSF6 BID	4.46e-05	197	88	5	a902aa05e5f711bcfdd9e19749ab636b597eb116
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	XYLT1 CYRIA NFATC2 DOCK11 GRAP2	4.46e-05	197	88	5	61ef3f417767c3f5296a26399da63e3e4f58faf8
ToppCell	COVID-19_Mild-Myeloid-Non-classical_Monocyte\|COVID-19_Mild / Disease group, lineage and cell class	CYRIA SLC8A1 IGSF6 CDH23 BID	4.46e-05	197	88	5	9c943d18f8e6cb0ce9f2158d50796fafae5c81d4
ToppCell	PBMC-Severe-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	9b8679b3dd8f4220d71f607b7080cb88d6e71129
ToppCell	PBMC-Severe-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	8b6b602ebe59b6dca6a22f17385d3160ff3ac67e
ToppCell	PBMC-Severe-Myeloid-Non-classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	b9030390316baf456135f85f831394e1e11ecf3e
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	cbbdd44dfa95370c0fbaa65ba71d86bfee0ea379
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	3bc3dbd178043deadd7eef413b2761dc003abd6e
ToppCell	PBMC-Severe-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	d36a3cda7e5f385d2391e9b0dfb027d3c4549320
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VAC14 SLC8A1 NFATC2 CDH23 BID	4.57e-05	198	88	5	fa5c15a656d4132950092919600e270f1fd79abf
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	9b47585653aaebd033c9b7bba93c7a7c35a4d60e
ToppCell	PBMC-Severe-Myeloid-Non-classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	5436c3ed16e10e00c686f1ab0b0a68728a1a9985
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC8A1 IGSF6 WASHC4 DOCK11 GNAI2	4.57e-05	198	88	5	885cbd3695b466a161cf318d35ebbdfcc0c19cec
ToppCell	COVID-19_Moderate-Non-classical_Monocyte\|World / disease group, cell group and cell class	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	8449934e20bb2a34079fb642cae0d4647b9efe51
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	8b5d30312bbcabc6911ff03e5028766d77203dff
ToppCell	Control-Myeloid-Non-classical_Monocyte\|Control / Disease group, lineage and cell class	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	ae0a51e63e2751a6d9dc0c8a3852680949173523
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	7d8fade2583c07a33dd83057cbce08e9fc77987a
ToppCell	Healthy_donor-Non-classical_Monocyte\|Healthy_donor / disease group, cell group and cell class (v2)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	d4eae333fa100db3ea2d4cbe7a1d6ab14816f0e2
ToppCell	PBMC-Severe-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	4f67067d8142ca11b2d80195dac8d62a8d24d52c
ToppCell	Healthy/Control-Non-classical_Monocyte\|Healthy/Control / Disease group and Cell class	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	0badaf1fa5328d06291c3624d0f63196ffc81527
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYRIA SLC8A1 IGSF6 CDH23 BID	4.57e-05	198	88	5	165d60b111a17d517a420c434733eefb98da240d
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	XYLT1 CYRIA SLC8A1 CDH23 BID	4.68e-05	199	88	5	ac866ae110967c5867ff4601939b79861d43df54
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Monocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	XYLT1 CYRIA SLC8A1 CDH23 BID	4.79e-05	200	88	5	fd72fe6565e2f4885481991492d58c323ab1ad40
ToppCell	COVID-19-COVID-19_Severe-Myeloid-CD16+_Monocyte\|COVID-19_Severe / Disease, condition lineage and cell class	CYRIA SLC8A1 IGSF6 CDH23 BID	4.79e-05	200	88	5	58fbb7fc7159cbc417e6b457d60b7beba9b90da6
ToppCell	COVID-19-COVID-19_Mild-Myeloid-CD16+_Monocyte\|COVID-19_Mild / Disease, condition lineage and cell class	CYRIA SLC8A1 IGSF6 CDH23 BID	4.79e-05	200	88	5	5c0eb14bdf1bfeaf93f6c3d521529bd5a4de50ce
ToppCell	mild-Non-classical_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CYRIA SLC8A1 IGSF6 CDH23 BID	4.79e-05	200	88	5	334bab6bf93d455f3526e817ea5785d8b6ee531c
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Mesenchymal\|2m / Sample Type, Dataset, Time_group, and Cell type.	ABCA4 ANXA4 SLC5A6 ECEL1 STING1	4.79e-05	200	88	5	3b9dcc9df54fb81deb7dd4b2749b1bc746c1e563
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Monocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	XYLT1 CYRIA SLC8A1 CDH23 BID	4.79e-05	200	88	5	8872d5fa101d413fb43b4231d476878678543035
ToppCell	severe-Non-classical_Monocyte\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CYRIA SLC8A1 IGSF6 CDH23 BID	4.79e-05	200	88	5	6cc7190a4ffc6c06335072f3b5b5f98eae36e2ce
ToppCell	Control-Control-Myeloid-CD16+_Monocyte\|Control / Disease, condition lineage and cell class	CYRIA SLC8A1 IGSF6 CDH23 BID	4.79e-05	200	88	5	8dd124a5aca897652ea68efbfc5a167b4cf31aef
ToppCell	severe-Non-classical_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CYRIA SLC8A1 IGSF6 CDH23 BID	4.79e-05	200	88	5	804c6e998fb7a29ca1b98f53d5dbcb7ae5a47e7a
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	XYLT1 CYRIA SLC8A1 CDH23 BID	4.79e-05	200	88	5	fc061de0db2e8b5ca47f5e2a1e861018e7f1b582
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Nonclassical_Monocyte\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC8A1 IGSF6 CDH23 GNAI2 BID	4.79e-05	200	88	5	97f261d56bc6c55683eb4c42670d00b9a6992a26
ToppCell	Severe-B_naive-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 SETX WASHC4 GPAT4	1.71e-04	140	88	4	683ee5e103f0c68cbbec019249404d381dbc39f3
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8\|TCGA-Bladder / Sample_Type by Project: Shred V9	TANC2 CCNG2 SLC9A2 OMP	2.23e-04	150	88	4	1aa9320d97ff10994ea024751790524fe133aba9
ToppCell	PND01-03-samps-Myeloid-Macrophage-macrophage-B\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	B4GALNT1 DNAH12 ASPM FER1L5	2.34e-04	152	88	4	5ce8920aedd39a4daf7082153b5e213707c14227
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC8A1 SLC9A2 ABCA12 LRP1B	2.40e-04	153	88	4	9b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC8A1 LRRC49 FER1L5 LRP1B	2.40e-04	153	88	4	79c4f4ccdc8249c8461075c73491bc3b2d13344a
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SLC8A1 FN1 PROCR ECEL1	2.46e-04	154	88	4	e65e4636646164610f33f7bbac0d879a3ea55986
ToppCell	Control-B_naive-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 SETX WASHC4 GPAT4	2.52e-04	155	88	4	0a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
Disease	Calcium channel blocker use measurement	LRPPRC FAT1 NFATC2 B4GALNT2 ENPEP PRDM6	3.59e-05	213	85	6	EFO_0009930
Disease	chronic granulomatous disease (implicated_via_orthology)	NCF1C NCF1B	8.15e-05	5	85	2	DOID:3265 (implicated_via_orthology)
Disease	D dimer measurement	ABCA4 PROCR FGG	8.85e-05	30	85	3	EFO_0004507
Disease	syndromic X-linked intellectual disability (implicated_via_orthology)	PHF2 HUWE1	2.27e-04	8	85	2	DOID:0060309 (implicated_via_orthology)
Disease	Liver Cirrhosis, Experimental	CYRIA FAT1 IGSF6 COL12A1 PROCR ANXA4 GNAI2 ENPEP ATP10D	3.91e-04	774	85	9	C0023893
Disease	sitting height ratio	PRKD2 TBX4 NFATC2	4.35e-04	51	85	3	EFO_0007118
Disease	Orofacial cleft	TANC2 CYRIA ABCA4	4.35e-04	51	85	3	HP_0000202
Disease	rheumatoid arthritis (implicated_via_orthology)	NCF1C NCF1B	5.31e-04	12	85	2	DOID:7148 (implicated_via_orthology)
Disease	creatinine measurement	PRKD2 SLC8A1 SLC9A2 WIPI1 TBX4 RNLS PROCR TMC6 ZFHX3 STAT3	5.77e-04	995	85	10	EFO_0004518
Disease	atrial fibrillation	KCND3 ANXA4 ZFHX3 KIF3C ENPEP PRDM6	7.20e-04	371	85	6	EFO_0000275
Disease	Animal Mammary Neoplasms	FN1 ANXA4 GNAI2 STAT3	7.70e-04	142	85	4	C0024667
Disease	Mammary Carcinoma, Animal	FN1 ANXA4 GNAI2 STAT3	7.70e-04	142	85	4	C1257925
Disease	serum alanine aminotransferase measurement	XYLT1 ARHGEF19 COL12A1 NEDD4L PROCR DNAH2 DYRK1A USP48 ATP10D	8.92e-04	869	85	9	EFO_0004735
Disease	Antihypertensive use measurement	NEDD4L NFATC2 PKP4 ENPEP PRDM6	1.03e-03	265	85	5	EFO_0009927
Disease	Mammary Neoplasms, Experimental	FN1 ANXA4 GNAI2 STAT3	1.07e-03	155	85	4	C0024668
Disease	Ischemic stroke, venous thromboembolism, stroke, Abnormal thrombosis, deep vein thrombosis, pulmonary embolism	PROCR FGG	1.08e-03	17	85	2	EFO_0000712, EFO_0003827, EFO_0003907, EFO_0004286, HP_0001977, HP_0002140
Disease	Carcinomatosis	FN1 ANXA4 GNAI2 STAT3	1.28e-03	163	85	4	C0205699
Disease	Carcinoma, Spindle-Cell	FN1 ANXA4 GNAI2 STAT3	1.28e-03	163	85	4	C0205697
Disease	Undifferentiated carcinoma	FN1 ANXA4 GNAI2 STAT3	1.28e-03	163	85	4	C0205698
Disease	Anaplastic carcinoma	FN1 ANXA4 GNAI2 STAT3	1.28e-03	163	85	4	C0205696
Disease	Carcinoma	FN1 ANXA4 GNAI2 STAT3	1.31e-03	164	85	4	C0007097
Disease	gut microbiome measurement, bone density	COL12A1 NFATC2 CHST8	1.50e-03	78	85	3	EFO_0003923, EFO_0007874
Disease	heart failure, diabetes mellitus, stroke, atrial fibrillation, mortality, coronary artery disease, cancer	DNAH2 ZFHX3	1.51e-03	20	85	2	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004352, MONDO_0004992
Disease	coagulation factor measurement	ORM1 ASPM	1.51e-03	20	85	2	EFO_0004634
Disease	bone density, lean body mass	ZBTB40 MEPE	1.66e-03	21	85	2	EFO_0003923, EFO_0004995
Disease	prothrombin time measurement	PROCR FGG	1.66e-03	21	85	2	EFO_0008390
Disease	venous thromboembolism, plasminogen activator inhibitor 1 measurement	PROCR FGG	1.66e-03	21	85	2	EFO_0004286, EFO_0004792
Disease	severe acute respiratory syndrome, COVID-19	DMRT3 KCND3 ANXA4 ZFHX3 LRP1B PRDM6	1.87e-03	447	85	6	EFO_0000694, MONDO_0100096
Disease	information processing speed	CDH23 ZFHX3 LRP1B	1.92e-03	85	85	3	EFO_0004363
Disease	venous thromboembolism, tissue plasminogen activator measurement	PROCR FGG	1.99e-03	23	85	2	EFO_0004286, EFO_0004791
Disease	coronary artery disease	PHF2 PRKD2 WIPI1 FN1 RNLS PROCR B4GALNT2 GNAI2 USP48 PRDM6	2.26e-03	1194	85	10	EFO_0001645
Disease	Neurodevelopmental Disorders	TANC2 PHF2 DYRK1A	2.48e-03	93	85	3	C1535926

Protein segments in the cluster

Peptide	Gene	Start	Entry
TSSQRSTLTYQRNNY	PKP4	456	Q99569
QNICQYRSLQYSRQE	CCAR2	751	Q8N163
VTFTLQQLNAYNRTR	PROCR	161	Q9UNN8
NYNNSILARVYRDFQ	ABCA4	96	P78363
LNRQLQLVTYSSRSY	B4GALNT1	216	Q00973
KTYNTYRSNTLTRVQ	B4GALNT2	536	Q8NHY0
RRTYSSQVIYNLTGQ	ABCA12	1866	Q86UK0
IVSRRTAQNLHNSYY	CCNG2	271	Q16589
SCQLGQRIYQYIQSR	DYRK1A	311	Q13627
IRRISQTYQQQYGRS	ANXA4	121	P09525
QAYSIDNLNQITYRF	CDH23	1336	Q9H251
TAATLIQSNYRRYRQ	ASPM	2191	Q8IZT6
YVNNRIRTTKYTLLN	ATP10D	71	Q9P241
SVYRLNFTQQQRLQF	OMP	51	P47874
TNQAYQERTYQRLLL	ARHGEF19	471	Q8IW93
SSSRNRQRFNLNQYL	FAT1	4476	Q14517
RYQQQNPAAVLYQRS	NFATC2	741	Q13469
LQAASHYRQNRNSLY	NUP133	736	Q8WUM0
IQNDFSYYRRTISRN	CYRIA	151	Q9H0Q0
VIVSNFSRIYHQNQR	KCND1	406	Q9NSA2
VIVSNFSRIYHQNQR	KCND3	401	Q9UK17
LYATNSDNYNIVRIN	LRP1B	426	Q9NZR2
SQNYFTNRQRLNKEY	MEPE	86	Q9NQ76
YRSLVYQLNFDQTLR	MGAT2	91	Q10469
LINYNNSITNSVYSR	CCNYL2	281	Q5T2Q4
ISRSQNQQYLVRASY	KIF3C	131	O14782
NTYQINARTELAVRY	PDE9A	361	O76083
NQRVELFQLNYLYTT	DNAH12	1721	Q6ZR08
NYASRAQNIRNRATV	KIF7	341	Q2M1P5
ITLFQNNTTNRYYKE	PRKD2	426	Q9BZL6
TNRATLNYTTRDFYN	LRRC49	601	Q8IUZ0
NRVTYQRLIASYCNV	LRPPRC	196	P42704
DYLVNRYTLNNRNLG	ENPEP	876	Q07075
RNVYQNYRQFIETAR	EXOC8	61	Q8IYI6
DVYQQYRSLTRQSSD	HUWE1	1986	Q7Z6Z7
VRLYDNFTVYNQRVN	ECEL1	651	O95672
EYILSNQGYVRQLSQ	INF2	116	Q27J81
SQDAYRRNSVRFLQQ	NCF1B	321	A6NI72
SQDAYRRNSVRFLQQ	NCF1C	296	A8MVU1
NLTVVQYRSNIFYRA	PRDM6	336	Q9NQX0
SSIRYLQEIYNSNNQ	FGG	131	P02679
NNTYENRRVLSNYER	IGSF6	226	O95976
SSVSQYNRLDQYEIR	DOCK11	1266	Q5JSL3
SDTRTEFNLNQYYQR	COL12A1	186	Q99715
LSRTNYNFQYISLRL	GPAT4	146	Q86UL3
TLQQQYQLRSQYVSP	DMRT3	396	Q9NQL9
YNQYSQRYHQRTNTN	FN1	2441	P02751
NFINQNLRTYVRSLA	BID	176	P55957
REYQTRQDQCIYNTT	ORM1	81	P02763
VIYNRQQNTQRFYLG	EML5	711	Q05BV3
SIRLNYSQVSNKNLY	DZANK1	526	Q9NVP4
NKLVDYYRTNSISRQ	GRAP2	126	O75791
YYRTNSISRQKQIFL	GRAP2	131	O75791
VYTLYSLAVQQLSRQ	DNAH2	1956	Q9P225
VRYNYLVSSLVANQN	DNAH2	2396	Q9P225
QLYQQSRAYVAANQR	C19orf25	61	Q9UFG5
RERIYSNNQYARQFI	VAC14	181	Q08AM6
QARIRTYNQHYNNLL	STING1	176	Q86WV6
IRRSVQATYNTQVNF	XAB2	726	Q9HCS7
LSDNLRQVRYSYLQQ	TRIM27	331	P14373
YYSTNRKRVLNVTNL	PHF2	181	O75151
SAQIASYQRQYRNEI	SLC9C1	521	Q4G0N8
SYQRQYRNEILSQSA	SLC9C1	526	Q4G0N8
YIYQARNLVSNQILT	FER1L5	1081	A0AVI2
YGVNQAQVQRYLSSR	SLC5A6	271	Q9Y289
QIPNTNIYRSINDYR	SLC26A8	531	Q96RN1
CRQYRAVVYSNTIQS	GNAI2	66	P04899
YVYNRNLKTNRQTEA	SETX	2271	Q7Z333
AQAYQDNLYRQLSRD	TANC2	1956	Q9HCD6
QQVLAVDARYNAYRT	WDR13	6	Q9H1Z4
YFAQLSALQRQRTYD	CHST8	391	Q9H2A9
RRLQNSYTASQRTNQ	TJAP1	96	Q5JTD0
CLYQITSVIQYRANN	USPL1	441	Q5W0Q7
YLHRQVLQVSRQYSN	XYLT1	366	Q86Y38
SRNLYQIRQRTLSYN	SLC9A2	606	Q9UBY0
QRQQLEAVSYSSRYA	RNLS	181	Q5VYX0
SRSQNQQYLVRASYL	KIF3B	131	O15066
QQYSRFLQESNVLYQ	STAT3	66	P40763
YLYNLNNQIFIERTS	WASHC4	796	Q2M389
LYRCQVYARSSNQNS	ZNF233	341	A6NK53
AIISQYYNRTVQLRC	TMC6	96	Q7Z403
FSVYNQLSQSQVRER	TBX4	471	P57082
NYSYSSNILSIRLNR	WIPI1	96	Q5MNZ9
RNVARSLNSQLVYEY	TUT4	681	Q5TAX3
QQQRDLREYTQATIY	USP48	851	Q86UV5
RLLQQTVRSSQYDKY	TBC1D2B	366	Q9UPU7
VQTVVSLLRLYQYSN	ZBTB40	306	Q9NUA8
LSQRRRAYSTNQITN	VWA5B1	651	Q5TIE3
TNDRYIRTSNLNYQC	ZFHX3	2316	Q15911
YQVLSQQQKSRAFYR	SLC8A1	351	P32418
LGRTYYVNHNNRTTQ	NEDD4L	206	Q96PU5