Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmetalloendopeptidase activity

ADAMTS6 ADAMTS20 ADAMTS9

1.35e-04120173GO:0004222
GeneOntologyMolecularFunctionmetallopeptidase activity

ADAMTS6 ADAMTS20 ADAMTS9

6.07e-04200173GO:0008237
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

HYAL3 GANAB

3.41e-03103172GO:0004553
GeneOntologyBiologicalProcesspositive regulation of melanocyte differentiation

ADAMTS20 ADAMTS9

6.38e-065172GO:0045636
GeneOntologyBiologicalProcessregulation of melanocyte differentiation

ADAMTS20 ADAMTS9

1.34e-057172GO:0045634
GeneOntologyBiologicalProcesspositive regulation of pigment cell differentiation

ADAMTS20 ADAMTS9

1.34e-057172GO:0050942
GeneOntologyBiologicalProcesspositive regulation of developmental pigmentation

ADAMTS20 ADAMTS9

2.29e-059172GO:0048087
GeneOntologyBiologicalProcessregulation of pigment cell differentiation

ADAMTS20 ADAMTS9

2.29e-059172GO:0050932
GeneOntologyBiologicalProcessregulation of developmental pigmentation

ADAMTS20 ADAMTS9

6.67e-0515172GO:0048070
GeneOntologyBiologicalProcessregulation of pigmentation

ADAMTS20 ADAMTS9

8.63e-0517172GO:0120305
GeneOntologyBiologicalProcessmelanocyte differentiation

ADAMTS20 ADAMTS9

2.56e-0429172GO:0030318
GeneOntologyBiologicalProcesspigment cell differentiation

ADAMTS20 ADAMTS9

4.90e-0440172GO:0050931
GeneOntologyBiologicalProcessdevelopmental pigmentation

ADAMTS20 ADAMTS9

1.03e-0358172GO:0048066
GeneOntologyCellularComponentextracellular matrix

ADAMTS6 ADAMTS20 ADAMTS9 SSPOP

1.29e-03656164GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

ADAMTS6 ADAMTS20 ADAMTS9 SSPOP

1.31e-03658164GO:0030312
DomainTSP_1

ADAMTS6 ADAMTS20 ADAMTS9 SSPOP

3.47e-0763184PF00090
DomainTSP1

ADAMTS6 ADAMTS20 ADAMTS9 SSPOP

3.94e-0765184SM00209
DomainTSP1_rpt

ADAMTS6 ADAMTS20 ADAMTS9 SSPOP

3.94e-0765184IPR000884
DomainTSP1

ADAMTS6 ADAMTS20 ADAMTS9 SSPOP

3.94e-0765184PS50092
DomainPept_M12B_GON-ADAMTSs

ADAMTS20 ADAMTS9

8.77e-072182IPR012314
DomainGON

ADAMTS20 ADAMTS9

8.77e-072182PF08685
DomainGON

ADAMTS20 ADAMTS9

8.77e-072182PS51046
DomainADAM_spacer1

ADAMTS6 ADAMTS20 ADAMTS9

1.32e-0623183IPR010294
DomainADAM_spacer1

ADAMTS6 ADAMTS20 ADAMTS9

1.32e-0623183PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS6 ADAMTS20 ADAMTS9

1.50e-0624183IPR013273
DomainPeptidase_M12B_N

ADAMTS6 ADAMTS20 ADAMTS9

6.72e-0639183IPR002870
DomainPep_M12B_propep

ADAMTS6 ADAMTS20 ADAMTS9

6.72e-0639183PF01562
DomainDISINTEGRIN_1

ADAMTS6 ADAMTS20 ADAMTS9

7.26e-0640183PS00427
DomainADAM_MEPRO

ADAMTS6 ADAMTS20 ADAMTS9

7.26e-0640183PS50215
DomainDISINTEGRIN_2

ADAMTS6 ADAMTS20 ADAMTS9

7.26e-0640183PS50214
DomainReprolysin

ADAMTS6 ADAMTS20 ADAMTS9

7.26e-0640183PF01421
DomainPeptidase_M12B

ADAMTS6 ADAMTS20 ADAMTS9

7.26e-0640183IPR001590
DomainDisintegrin_dom

ADAMTS6 ADAMTS20 ADAMTS9

7.83e-0641183IPR001762
DomainMetalloPept_cat_dom

ADAMTS6 ADAMTS20 ADAMTS9

6.12e-0581183IPR024079
Domain-

ADAMTS6 ADAMTS20 ADAMTS9

6.12e-05811833.40.390.10
DomainZINC_PROTEASE

ADAMTS6 ADAMTS20 ADAMTS9

1.08e-0498183PS00142
DomainLDLR_class-A_CS

SSPOP LRP12

6.70e-0440182IPR023415
DomainLdl_recept_a

SSPOP LRP12

8.47e-0445182PF00057
Domain-

SSPOP LRP12

8.85e-04461824.10.400.10
DomainLDLRA_1

SSPOP LRP12

9.64e-0448182PS01209
DomainLDrepeatLR_classA_rpt

SSPOP LRP12

1.00e-0349182IPR002172
DomainLDLa

SSPOP LRP12

1.00e-0349182SM00192
DomainLDLRA_2

SSPOP LRP12

1.00e-0349182PS50068
DomainGlycoside_hydrolase_SF

HYAL3 GANAB

1.17e-0353182IPR017853
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS6 ADAMTS20 ADAMTS9 SSPOP

8.89e-0839164MM15165
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS6 ADAMTS20 ADAMTS9 SSPOP

8.89e-0839164M27417
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS6 ADAMTS20 ADAMTS9 SSPOP

8.63e-0768164M27303
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS6 ADAMTS20 ADAMTS9 SSPOP

5.73e-06109164MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS6 ADAMTS20 ADAMTS9 SSPOP

6.16e-06111164M27416
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS6 ADAMTS20 ADAMTS9 SSPOP

1.68e-05143164M27275
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTS6 ADAMTS20 ADAMTS9 SSPOP

1.49e-04250164M27554
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS6 ADAMTS20 ADAMTS9 SSPOP

7.54e-087519420637190
Pubmed

Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1.

ADAMTS20 ADAMTS9

2.83e-07219212514189
Pubmed

A new Adamts9 conditional mouse allele identifies its non-redundant role in interdigital web regression.

ADAMTS20 ADAMTS9

8.48e-07319224753090
Pubmed

Degradomic Identification of Membrane Type 1-Matrix Metalloproteinase as an ADAMTS9 and ADAMTS20 Substrate.

ADAMTS20 ADAMTS9

8.48e-07319237169079
Pubmed

ADAMTS9 and ADAMTS20 are differentially affected by loss of B3GLCT in mouse model of Peters plus syndrome.

ADAMTS20 ADAMTS9

2.82e-06519231600785
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

ADAMTS20 ADAMTS9 SSPOP

5.64e-066419322261194
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

SSPOP LRP12 GANAB

7.72e-067119333541421
Pubmed

The secreted metalloprotease ADAMTS20 is required for melanoblast survival.

ADAMTS20 ADAMTS9

7.90e-06819218454205
Pubmed

Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation.

ADAMTS20 ADAMTS9

7.90e-06819221041365
Pubmed

ADAMTS: a novel family of extracellular matrix proteases.

ADAMTS6 ADAMTS9

1.27e-051019211167130
Pubmed

Hydrocephalus in mouse B3glct mutants is likely caused by defects in multiple B3GLCT substrates in ependymal cells and subcommissural organ.

ADAMTS20 ADAMTS9

1.55e-051119233909046
Pubmed

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

ADAMTS20 ADAMTS9

1.86e-051219225770910
Pubmed

Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation.

ADAMTS20 ADAMTS9

3.83e-051719222183742
Pubmed

ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression.

ADAMTS20 ADAMTS9

5.34e-052019219922873
Pubmed

ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation.

ADAMTS20 ADAMTS9

7.10e-052319226027930
Pubmed

Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.

ADAMTS20 ADAMTS9

7.10e-052319230814516
Pubmed

Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.

ADAMTS20 ADAMTS9

8.42e-052519229475039
Pubmed

Galnt1 is required for normal heart valve development and cardiac function.

ADAMTS20 ADAMTS9

1.76e-043619225615642
Pubmed

Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis.

ADAMTS9 HYAL3

1.96e-043819218267097
Pubmed

Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.

PRMT2 KDM6A

2.64e-044419224183668
Cytoband21q22.3

PRMT2 ZNF295-AS1

1.28e-0312819221q22.3
CytobandEnsembl 112 genes in cytogenetic band chr21q22

PRMT2 ZNF295-AS1

1.05e-02377192chr21q22
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS6 ADAMTS20 ADAMTS9

2.80e-071913350
GeneFamilySolute carriers

SLCO4A1 SLC12A3

3.17e-02395132752
CoexpressionNABA_ECM_REGULATORS

ADAMTS6 ADAMTS20 ADAMTS9 HYAL3

2.31e-05238194M3468
CoexpressionNABA_ECM_REGULATORS

ADAMTS6 ADAMTS20 ADAMTS9 HYAL3

2.46e-05242194MM17062
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLF15 SSPOP SLC12A3

4.03e-05159193fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLF15 SSPOP SLC12A3

4.03e-05159193aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLF15 SSPOP SLC12A3

4.03e-051591938bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAMTS6 ADAMTS9 RP1L1

4.58e-05166193f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF15 SLCO4A1 ADAMTS9

5.17e-05173193f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF15 SLCO4A1 ADAMTS9

5.17e-05173193c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(other)|COVID-19 / group, cell type (main and fine annotations)

ADAMTS6 SLCO4A1 ADAMTS9

5.92e-0518119326eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCellCOVID-19-lung-Artery_EC|lung / Disease (COVID-19 only), tissue and cell type

ADAMTS6 SLCO4A1 ADAMTS9

6.62e-05188193eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCellCOVID-19-Endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

ADAMTS6 SLCO4A1 ADAMTS9

6.83e-051901939fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

ADAMTS6 SLCO4A1 ADAMTS9

6.83e-05190193812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS6 SLCO4A1 ADAMTS9

7.61e-05197193ad4a3b5da2190be9495382a2952991e1de9f190d
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS6 SLCO4A1 ADAMTS9

7.72e-05198193f7aa809040fa9f5782b92eec1f289d690eb5c7bd
ToppCellCOVID-19-lung-Capillary_2|lung / Disease (COVID-19 only), tissue and cell type

ADAMTS6 SLCO4A1 ADAMTS9

7.84e-05199193793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS6 SLCO4A1 ADAMTS9

7.84e-051991939735a1dc10910f02f1106b20ae5ab4c09c21305e
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS6 SLCO4A1 ADAMTS9

7.96e-052001935ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCellParenchyma_COVID-19-Endothelial-TX|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ADAMTS6 SLCO4A1 ADAMTS9

7.96e-05200193abcbd5a156aa4fd51d284441388975c81c0b88ae
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Cadm2_(Cadm2_state)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADAMTS6 HYAL3

5.50e-048219201a4d47d9e0dee68a5277ed1534338cec80f75d1
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Cadm2_(Cadm2_state)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADAMTS6 HYAL3

5.50e-0482192c1489097c291f413f3cfa5e26f8182ec872328fd
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS20 SLC12A3

7.06e-049319293a8d3ad978e4cd450f7a69a4cbac1a59038e80d
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-2|TCGA-Ovary / Sample_Type by Project: Shred V9

ADAMTS20 C1orf167

1.08e-03115192ecc28d8413898b893f052914fd180de9468b70e4
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Desmoid_Tumor|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ADAMTS20 ADAMTS9

1.15e-03119192d8fbea9ded96fcc3ebdfb4d28873c563427ce811
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Desmoid_Tumor-7|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ADAMTS20 ADAMTS9

1.15e-031191929e38f13bf98b9ee44b178300e6f80fd08a006296
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-AT1_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS20 SLC12A3

1.27e-03125192b1a12400f7070bdf09e87974c548a8b82e92b65e
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SSPOP SLC12A3

1.37e-031301926c6a8b77af08b30b424d4f5def37315d3c6e28b2
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_fibroblast-mesenchymal_B|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SSPOP SLC12A3

1.37e-031301920706092f6b466585b3b4808b3b982a122d66cfcf
ToppCellfacs-Aorta-Heart-3m-Myeloid-professional_antigen_presenting_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSPOP RP1L1

1.57e-03139192292533e04178dd36d57377562077f9deb2cb9746
ToppCellfacs-Aorta-Heart-3m-Myeloid-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSPOP RP1L1

1.57e-0313919222a769d5195ed761ef333ef542746e1ba617a698
ToppCellBronchial_Biopsy-Epithelial-Goblet_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

SLCO4A1 C1orf167

1.70e-03145192e932361734839c14ffa0c1e028dcef9c833f884f
ToppCellBronchial_Biopsy-Epithelial-Goblet_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SLCO4A1 C1orf167

1.72e-03146192a4f2e3ea79e7154873c01739672ec6454547e6a6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDC42BPB ZNF295-AS1

1.77e-03148192fd0d8386b94adb1bdc993fbb44d2d87852bfd7f0
ToppCell356C-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SSPOP PRMT2

1.80e-0314919295b21d67d6c335330a508f78d5cc074fdaf92275
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS6 SSPOP

1.82e-03150192afd651c654e715414eff64cf3a37378d057a56a2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 RP1L1

1.92e-031541921899138c096c08d8aee6b1970b7c0081e14c88a8
ToppCellIIH-CD8-exh_CD4|IIH / Condition, Cell_class and T cell subcluster

LRP12 C1orf167

1.92e-03154192a2f51a3c5455fe2483e438375ea856afce8262fe
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO4A1 SLC12A3

1.97e-031561925d97755db872d51522f6412a93704f3c79a084cd
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO4A1 SLC12A3

1.99e-03157192fc127e7720649e746f3d3f5c2e9e63784767106a
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAMTS6 SSPOP

1.99e-031571920a552abfd139afc8516c38ca568f9922511dddce
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO4A1 SLC12A3

1.99e-0315719266a191cef4aa00811bb04462310d012610006f85
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS6 PRMT2

2.04e-03159192e967b557fe6ae4879d36f62c0297cbf6a2ad1ce9
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS6 PRMT2

2.04e-031591929db971130509c62d439e0cab16588a4d994d7aa0
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLCO4A1 SSPOP

2.04e-031591928d958d79f5eb3ab683d1245ae7f4f22a2cefbc55
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SLCO4A1 PLEKHG7

2.07e-031601926de505bfe1fbbe984718740a9cf43d0e02ff452e
ToppCellfacs-Skin-Anagen-3m-Epithelial-inner_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS6 ADAMTS20

2.09e-031611928d2987271da52fd8353557ac6faa4f7a4be0ed2a
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAMTS6 HYAL3

2.12e-0316219225bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCell10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3|Liver / Manually curated celltypes from each tissue

LRP12 ZNF295-AS1

2.14e-031631927f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS6 SLCO4A1

2.17e-031641923cd80e6275f0f9b5667912139d15ebf5e6b17f2f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 ADAMTS20

2.19e-03165192e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 ADAMTS20

2.19e-03165192b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 ADAMTS20

2.19e-03165192d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_Erythro-Mega|bone_marrow / Manually curated celltypes from each tissue

ADAMTS9 HYAL3

2.22e-03166192a853005a5587d42daecdf2e23a93109919021a4f
ToppCellwk_15-18-Hematologic-Myeloid-HSC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SLCO4A1 HYAL3

2.25e-031671925f793eafbb593317caa9afd8267e561e09058ddb
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B|GI_small-bowel / Manually curated celltypes from each tissue

PLEKHG7 SLC12A3

2.27e-031681925535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCellwk_20-22-Hematologic-Myeloid-CMP|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SLCO4A1 HYAL3

2.27e-03168192e223bd7ae2a28c007e8b365f30d50d3bee83ba38
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

PLEKHG7 SLC12A3

2.27e-031681928e025bb0541746e232b77ac0e31412ae71420c47
ToppCellwk_15-18-Hematologic-Myeloid-CMP|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SLCO4A1 HYAL3

2.27e-031681929fc9c93ab7513bf4dfefc866b97c703208a238c9
ToppCell15-Distal-Epithelial-Multiciliated_cell|Distal / Age, Tissue, Lineage and Cell class

PLEKHG7 ZNF295-AS1

2.30e-03169192425d89ab69e9f9eb3df84056676423e390cc6ab1
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS6 ADAMTS9

2.33e-03170192667443062882642211ad116043775ef8eda38859
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO4A1 RP1L1

2.33e-0317019217bd7fd25a2657cb536ad47e294332920f759e95
ToppCell3'_v3-bone_marrow-Lymphocytic_B-ABC_aged-B_naive|bone_marrow / Manually curated celltypes from each tissue

CDC42BPB SLC12A3

2.35e-03171192fcc31a9a69f96de10d1324a5a4fbfe4289bf4984
ToppCellnormal_Lung-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

LRP12 GANAB

2.35e-03171192f49dfe11ae66d82125b577c48345a13683d7bb7b
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

SLCO4A1 SSPOP

2.38e-03172192c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-5|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

PLEKHG7 ZNF295-AS1

2.38e-031721926b8a8d3b97c10b9d092307eed3cacbd2745df185
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAMTS9 PLEKHG7

2.41e-031731925295ed31648abf8edff214cf67cd4769f20f9e6d
ToppCellmild_COVID-19_(asymptomatic)-B_memory|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

PLEKHG7 SLC12A3

2.41e-031731929082ad77b44f65b72094df6e502cce81b62fe81a
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RP1L1 SLC12A3

2.44e-03174192c2fc78dd6c440737ded59676961e4c7b923084ce
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RP1L1 SLC12A3

2.44e-03174192021ebc6ec022b992d7b25333ba0b7416371e041b
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF15 ADAMTS9

2.46e-031751923f1b2e23fec953148fb0711e523c463adb07dca4
ToppCell368C-Endothelial_cells-Endothelial-D|368C / Donor, Lineage, Cell class and subclass (all cells)

SLCO4A1 ADAMTS9

2.46e-03175192c4088b5f9fa145869cf5dd8bee7680b1c8fada42
ToppCell368C-Endothelial_cells-Endothelial-D-|368C / Donor, Lineage, Cell class and subclass (all cells)

SLCO4A1 ADAMTS9

2.46e-03175192ca0d3e3a0a271cccdd3881b055fecb626712478d
ToppCellwk_15-18-Hematologic-Myeloid-aDC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

C1orf167 SLC12A3

2.46e-03175192c31178d7a5a19d7afd336c9ec0e5c493655a6aa4
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHG7 ZNF295-AS1

2.49e-03176192dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO4A1 SSPOP

2.49e-031761923766e0533b103ec92ac75eba3df02e287efc53fa
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO4A1 SSPOP

2.49e-03176192aa1bada2175d8370fc71939a607407155259d195
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 SLCO4A1

2.49e-031761921df7b6ce2519ad99bacbbaf1a8d5929e11513faa
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLF15 ADAMTS20

2.52e-0317719259cf56c385c324f0844f20003d2b5049a2791e45
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSPOP HYAL3

2.55e-03178192f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCell390C-Endothelial_cells-Endothelial-E|390C / Donor, Lineage, Cell class and subclass (all cells)

SLCO4A1 ADAMTS9

2.55e-03178192ad6dc4a375664c919bd48c35c48a561fc5a7de8c
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO4A1 ADAMTS9

2.55e-03178192ba2f0585626988b511046630bc16be5c5fec3fb2
ToppCell390C-Endothelial_cells-Endothelial-E-|390C / Donor, Lineage, Cell class and subclass (all cells)

SLCO4A1 ADAMTS9

2.55e-03178192804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO4A1 LRP12

2.55e-03178192742ee0cb8cb585a5e34bd5b20aebe9bb99756e0c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAMTS6 PRMT2

2.55e-0317819231c847d7f7aa0f6d820afbb45d507992f5e9dc2f
ToppCellmetastatic_Brain-Endothelial_cells-Lymphatic_ECs|metastatic_Brain / Location, Cell class and cell subclass

ADAMTS9 LRP12

2.57e-0317919256fe381ffbaba3a4f2f587a3e367b0d11fbd4a2a
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTS6 ADAMTS9

2.57e-031791921ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS6 HYAL3

2.57e-0317919269c74b2ff43b43653005807654953daf21f932ec
ToppCellfacs-Pancreas-Exocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF15 ADAMTS9

2.57e-03179192bbfbfb32773346080127055b5aafa36bbf7d0942
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTS6 ADAMTS9

2.57e-031791922a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS6 ADAMTS9

2.60e-0318019240d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_GGT8P|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS20 SSPOP

2.63e-031811929842537f9a607d8557c43790008d175edab1f32c
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-4|TCGA-Endometrium / Sample_Type by Project: Shred V9

PLEKHG7 ZNF295-AS1

2.63e-0318119251d91b923920463245e95d65c6a5197e21d34d73
ToppCellEndothelial-A-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

SLCO4A1 ADAMTS9

2.69e-031831922c3f2c25c38f0598b4787d2ec335efe00fdc9751
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS6 ADAMTS9

2.69e-031831926e6128c5be5e0a2db6d84eecbf4dddd02d0216f8
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS9 SLC12A3

2.69e-031831922f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCell3'-Adult-SmallIntestine-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS6 ADAMTS9

2.69e-03183192f8212bf8a8b8312434ae030261c558c147f61747
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS6 ADAMTS9

2.69e-031831925e361be3ae3fe05098968e58427630127bd12675
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS6 ADAMTS9

2.69e-03183192858682df5592c6856487487a7baabd6e60e63a38
ToppCellfacs-Marrow-KLS-18m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSCB HYAL3

2.69e-03183192b60638680b1882b5a47f5dbce08f545e93bb4d0f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS20 SSPOP

2.72e-03184192ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellwk_15-18-Hematologic-Myeloid-MEP|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SLCO4A1 HYAL3

2.72e-0318419219d61d0ab038b7e729e13a46f88b8cf31759485d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS20 SSPOP

2.72e-031841922cbed6462fea2622871bb7e49b0df3d984239281
ToppCellwk_20-22-Hematologic_Lymphocytic-B-CD5+_CCL22+_mature_B|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADAMTS6 SLCO4A1

2.72e-031841925bb775253a10a14360b06a46aba46d162a9bd1f8
Diseasescoliosis (implicated_via_orthology)

ADAMTS9 SSPOP

3.92e-065192DOID:0060249 (implicated_via_orthology)
Diseaseempathy measurement

ADAMTS20 PRMT2 ZNF295-AS1

1.70e-04170193EFO_0009183
Diseaselymphoid leukemia

KLF15 SLC12A3

2.72e-0438192EFO_0004289
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

ADAMTS20 ADAMTS9

2.06e-03105192DOID:9352 (implicated_via_orthology)
DiseaseBMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment

LRP12 GANAB

2.06e-03105192EFO_0007788, EFO_0008007, EFO_0008343
Diseasecorneal topography

ADAMTS6 ADAMTS20

2.22e-03109192EFO_0004345
Diseasesystolic blood pressure, alcohol drinking

C1orf167 RP1L1

3.04e-03128192EFO_0004329, EFO_0006335
Diseaseintraocular pressure measurement

ADAMTS6 ADAMTS20 LRP12

4.03e-03509193EFO_0004695
Diseaseobesity (implicated_via_orthology)

ADAMTS20 ADAMTS9

8.33e-03215192DOID:9970 (implicated_via_orthology)
Diseasecortical surface area measurement, neuroimaging measurement

ADAMTS20 ADAMTS9

9.24e-03227192EFO_0004346, EFO_0010736
Diseasecentral corneal thickness

ADAMTS6 ADAMTS20

1.66e-02309192EFO_0005213

Protein segments in the cluster

PeptideGeneStartEntry
CPWGSYQWEPGACPA

C1orf167

6

Q5SNV9
DWWWGERAGCCGYIP

PRMT2

66

P55345
PGPCPQWNYGNWGEC

ADAMTS20

1356

P59510
WCYQGDCVPFGTWPQ

ADAMTS6

541

Q9UKP5
LPWEIPCGGNWGCYT

LRP12

376

Q9Y561
PGDCEWFVVPEGYWG

KDM6A

1161

O15550
GKYGPECDWWSLGVC

CDC42BPB

256

Q9Y5S2
GPCPQWAYGNWGECT

ADAMTS9

1381

Q9P2N4
HCYWGWAGPTCQEPR

HYAL3

396

O43820
TGEKPFACTWPGCGW

KLF15

346

Q9UIH9
SNYPRCWNCGGPWGP

HSCB

36

Q8IWL3
SYATCPVDGAWGPWG

SSPOP

3466

A2VEC9
SDYEGWCWPGSAGYP

GANAB

496

Q14697
WCWPGSAGYPDFTNP

GANAB

501

Q14697
GQSVACGWWAFAPPC

SLCO4A1

81

Q96BD0
EVDPLCCVWEGYPWG

RP1L1

361

Q8IWN7
CCVWEGYPWGFSEPG

RP1L1

366

Q8IWN7
PGWGACEGLACSYGW

SLC12A3

411

P55017
WGSWGAPVGFPCYLS

PLEKHG7

71

Q6ZR37
YGCFVCGWAWPTLSP

ZNF295-AS1

121

Q8N0V1
KYGWFWVCPGGGDIC

ZC3H15

191

Q8WU90