Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	poly(A) binding	RBMS3 RBMS1 RBMS2	1.03e-04	29	63	3	GO:0008143
GeneOntologyMolecularFunction	poly(U) RNA binding	RBMS3 RBMS1 RBMS2	1.67e-04	34	63	3	GO:0008266
GeneOntologyMolecularFunction	poly-purine tract binding	RBMS3 RBMS1 RBMS2	2.15e-04	37	63	3	GO:0070717
GeneOntologyMolecularFunction	poly-pyrimidine tract binding	RBMS3 RBMS1 RBMS2	2.52e-04	39	63	3	GO:0008187
GeneOntologyMolecularFunction	ATP-dependent protein folding chaperone	HSPA1L HSPA2 HSPA8	2.72e-04	40	63	3	GO:0140662
GeneOntologyMolecularFunction	chromatin binding	ASXL3 GLI3 ZFP57 MITF ASH1L MBD5 NFAT5 JMJD1C STAT3	4.90e-04	739	63	9	GO:0003682
GeneOntologyBiologicalProcess	protein localization to nucleus	KPNA5 TNPO1 MAGED1 GLI3 GCKR SIX4 HSPA8 STAT3	1.39e-05	362	63	8	GO:0034504
GeneOntologyBiologicalProcess	establishment of protein localization to organelle	KPNA5 TNPO1 VPS13D GLI3 PEX1 GCKR HSPA1L HSPA8 STAT3	2.51e-05	515	63	9	GO:0072594
GeneOntologyBiologicalProcess	regulation of branch elongation involved in ureteric bud branching	HNF1B SIX4	2.75e-05	3	63	2	GO:0072095
GeneOntologyBiologicalProcess	protein import into nucleus	KPNA5 TNPO1 GLI3 GCKR HSPA8 STAT3	2.87e-05	195	63	6	GO:0006606
GeneOntologyBiologicalProcess	import into nucleus	KPNA5 TNPO1 GLI3 GCKR HSPA8 STAT3	3.40e-05	201	63	6	GO:0051170
GeneOntologyBiologicalProcess	branch elongation involved in ureteric bud branching	HNF1B SIX4	5.49e-05	4	63	2	GO:0060681
GeneOntologyBiologicalProcess	branching involved in ureteric bud morphogenesis	HNF1B MAGED1 GLI3 SIX4	5.56e-05	68	63	4	GO:0001658
GeneOntologyBiologicalProcess	ureteric bud morphogenesis	HNF1B MAGED1 GLI3 SIX4	7.75e-05	74	63	4	GO:0060675
GeneOntologyBiologicalProcess	regulation of mesonephros development	HNF1B SIX4	9.13e-05	5	63	2	GO:0061217
GeneOntologyBiologicalProcess	mesonephric tubule morphogenesis	HNF1B MAGED1 GLI3 SIX4	9.52e-05	78	63	4	GO:0072171
GeneOntologyBiologicalProcess	protein localization to organelle	KPNA5 TNPO1 VPS13D MAGED1 SZT2 GLI3 PEX1 GCKR SIX4 HSPA1L HSPA8 STAT3	9.85e-05	1091	63	12	GO:0033365
GeneOntologyBiologicalProcess	protein refolding	HSPA1L HSPA2 HSPA8	1.04e-04	30	63	3	GO:0042026
GeneOntologyBiologicalProcess	cellular anatomical entity morphogenesis	TENM4 TMOD2 SIX4 RFX2 VPS13B	1.15e-04	156	63	5	GO:0032989
GeneOntologyBiologicalProcess	cellular component assembly involved in morphogenesis	TENM4 TMOD2 SIX4 RFX2 VPS13B	1.15e-04	156	63	5	GO:0010927
GeneOntologyBiologicalProcess	nephron tubule morphogenesis	HNF1B MAGED1 GLI3 SIX4	1.45e-04	87	63	4	GO:0072078
GeneOntologyBiologicalProcess	nephron epithelium morphogenesis	HNF1B MAGED1 GLI3 SIX4	1.59e-04	89	63	4	GO:0072088
GeneOntologyBiologicalProcess	chaperone cofactor-dependent protein refolding	HSPA1L HSPA2 HSPA8	1.66e-04	35	63	3	GO:0051085
GeneOntologyBiologicalProcess	nephron morphogenesis	HNF1B MAGED1 GLI3 SIX4	1.73e-04	91	63	4	GO:0072028
GeneOntologyBiologicalProcess	renal tubule morphogenesis	HNF1B MAGED1 GLI3 SIX4	1.88e-04	93	63	4	GO:0061333
GeneOntologyBiologicalProcess	regulation of kidney development	HNF1B MAGED1 SIX4	2.12e-04	38	63	3	GO:0090183
GeneOntologyBiologicalProcess	ureteric bud elongation	HNF1B SIX4	2.54e-04	8	63	2	GO:0060677
GeneOntologyBiologicalProcess	'de novo' post-translational protein folding	HSPA1L HSPA2 HSPA8	2.66e-04	41	63	3	GO:0051084
GeneOntologyBiologicalProcess	developmental process involved in reproduction	HNF1B KMT2B TDRD9 ZFP57 ASH1L SIX4 RFX2 HSPA1L HSPA2 JMJD1C VPS13B STAU1	3.13e-04	1235	63	12	GO:0003006
GeneOntologyBiologicalProcess	ureteric bud development	HNF1B MAGED1 GLI3 SIX4	3.22e-04	107	63	4	GO:0001657
GeneOntologyBiologicalProcess	mesonephric tubule development	HNF1B MAGED1 GLI3 SIX4	3.58e-04	110	63	4	GO:0072164
GeneOntologyBiologicalProcess	mesonephric epithelium development	HNF1B MAGED1 GLI3 SIX4	3.58e-04	110	63	4	GO:0072163
GeneOntologyBiologicalProcess	nephron tubule development	HNF1B MAGED1 GLI3 SIX4	3.58e-04	110	63	4	GO:0072080
GeneOntologyBiologicalProcess	kidney morphogenesis	HNF1B MAGED1 GLI3 SIX4	3.71e-04	111	63	4	GO:0060993
GeneOntologyBiologicalProcess	'de novo' protein folding	HSPA1L HSPA2 HSPA8	3.75e-04	46	63	3	GO:0006458
GeneOntologyBiologicalProcess	intracellular protein transport	KPNA5 TNPO1 VPS13D GLI3 COPB2 PEX1 GCKR HSPA8 STAT3	3.92e-04	740	63	9	GO:0006886
GeneOntologyBiologicalProcess	mesonephros development	HNF1B MAGED1 GLI3 SIX4	3.97e-04	113	63	4	GO:0001823
GeneOntologyBiologicalProcess	renal tubule development	HNF1B MAGED1 GLI3 SIX4	4.38e-04	116	63	4	GO:0061326
GeneOntologyBiologicalProcess	nephron epithelium development	HNF1B MAGED1 GLI3 SIX4	6.35e-04	128	63	4	GO:0072009
Domain	Hud_Sxl_RNA	RBMS3 RBMS1 RBMS2	4.11e-06	10	62	3	IPR002343
Domain	-	HSPA1L HSPA2 HSPA8	7.50e-06	12	62	3	2.60.34.10
Domain	HSP70_peptide-bd	HSPA1L HSPA2 HSPA8	7.50e-06	12	62	3	IPR029047
Domain	-	HSPA1L HSPA2 HSPA8	9.73e-06	13	62	3	1.20.1270.10
Domain	Heat_shock_70_CS	HSPA1L HSPA2 HSPA8	9.73e-06	13	62	3	IPR018181
Domain	HSP70_C	HSPA1L HSPA2 HSPA8	9.73e-06	13	62	3	IPR029048
Domain	HSP70	HSPA1L HSPA2 HSPA8	1.89e-05	16	62	3	PF00012
Domain	HSP70_2	HSPA1L HSPA2 HSPA8	2.29e-05	17	62	3	PS00329
Domain	HSP70_3	HSPA1L HSPA2 HSPA8	2.29e-05	17	62	3	PS01036
Domain	HSP70_1	HSPA1L HSPA2 HSPA8	2.29e-05	17	62	3	PS00297
Domain	Hsp_70_fam	HSPA1L HSPA2 HSPA8	2.74e-05	18	62	3	IPR013126
Domain	VPS13_C	VPS13D VPS13B	6.48e-05	4	62	2	PF16909
Domain	SHR-BD	VPS13D VPS13B	6.48e-05	4	62	2	IPR009543
Domain	VPS13_C	VPS13D VPS13B	6.48e-05	4	62	2	IPR031645
Domain	SHR-BD	VPS13D VPS13B	6.48e-05	4	62	2	PF06650
Domain	UBA	VPS13D UBE2K UBQLN2	1.33e-04	30	62	3	SM00165
Domain	UBA	VPS13D UBE2K UBQLN2	2.30e-04	36	62	3	PF00627
Domain	VPS13_N	VPS13D VPS13B	3.00e-04	8	62	2	IPR026854
Domain	Chorein_N	VPS13D VPS13B	3.00e-04	8	62	2	PF12624
Domain	UBA	VPS13D UBE2K UBQLN2	4.19e-04	44	62	3	IPR015940
Domain	UBA	VPS13D UBE2K UBQLN2	5.09e-04	47	62	3	PS50030
Domain	UBA-like	VPS13D UBE2K UBQLN2	1.26e-03	64	62	3	IPR009060
Domain	Post-SET_dom	KMT2B ASH1L	1.26e-03	16	62	2	IPR003616
Domain	PostSET	KMT2B ASH1L	1.26e-03	16	62	2	SM00508
Domain	POST_SET	KMT2B ASH1L	1.26e-03	16	62	2	PS50868
Domain	AT_hook	KMT2B ASH1L	3.61e-03	27	62	2	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2B ASH1L	3.61e-03	27	62	2	IPR017956
Domain	ZF_PHD_2	KMT2B ASXL3 ASH1L	3.88e-03	95	62	3	PS50016
Domain	ZF_PHD_1	KMT2B ASXL3 ASH1L	4.00e-03	96	62	3	PS01359
Domain	PH	ARHGAP22 ARHGAP24 RALGPS2 ROCK1	7.05e-03	229	62	4	PF00169
Domain	SET	KMT2B ASH1L	8.18e-03	41	62	2	PF00856
Pathway	REACTOME_ATTENUATION_PHASE	HSPA1L HSPA2 HSPA8	1.40e-05	13	53	3	MM14952
Pathway	REACTOME_HSF1_DEPENDENT_TRANSACTIVATION	HSPA1L HSPA2 HSPA8	8.43e-05	23	53	3	MM14953
Pathway	REACTOME_PKR_MEDIATED_SIGNALING	HSPA1L HSPA2 HSPA8 STAT3	1.08e-04	66	53	4	MM17074
Pathway	REACTOME_ATTENUATION_PHASE	HSPA1L HSPA2 HSPA8	1.54e-04	28	53	3	M27254
Pathway	REACTOME_PKR_MEDIATED_SIGNALING	HSPA1L HSPA2 HSPA8 STAT3	1.87e-04	76	53	4	M48037
Pathway	REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES	KPNA5 HSPA1L HSPA2 HSPA8 STAT3	2.50e-04	151	53	5	M550
Pathway	REACTOME_HSF1_DEPENDENT_TRANSACTIVATION	HSPA1L HSPA2 HSPA8	3.86e-04	38	53	3	M27255
Pathway	REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES	HSPA1L HSPA2 HSPA8 STAT3	4.23e-04	94	53	4	MM14515
Pubmed	UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.	UBQLN2 HSPA1L HSPA2 HSPA8	7.36e-09	13	64	4	27477512
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	ARHGAP22 HNF1B SF3B3 COPB2 JMJD1C HSPA8 STAU1	4.98e-08	184	64	7	32908313
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	TNPO1 RNF214 SF3B3 MAGED1 CEP78 RBMS3 RBMS1 RBMS2 COPB2 ZNF622 STAU1	8.05e-08	724	64	11	36232890
Pubmed	Human transcription factor protein interaction networks.	RNF214 HNF1B MAGED1 KMT2B RBMS1 GLI3 COPB2 MITF TMOD2 SIX4 JMJD1C STAT3 STAU1 NPAT	2.56e-07	1429	64	14	35140242
Pubmed	RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.	TNPO1 RBMS2 HSPA1L HSPA2 PAIP1 HSPA8	3.28e-07	148	64	6	35676246
Pubmed	Hsp72 preserves muscle function and slows progression of severe muscular dystrophy.	ZFP57 DMD HSPA2	3.31e-07	8	64	3	22495301
Pubmed	ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.	SF3B3 MAGED1 HSPA1L HSPA2 HSPA8 ARAF	6.44e-07	166	64	6	35687106
Pubmed	A census of human transcription factors: function, expression and evolution.	ZNF14 GLI3 MITF ASH1L ZNF622 SIX4 NFAT5 RFX2 MBNL3 STAT3 NPAS2	7.61e-07	908	64	11	19274049
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	GLI3 ZFP57 ASH1L ZNF622 SIX4 NFAT5 RFX2 MBNL3 STAT3 NPAS2	2.11e-06	808	64	10	20412781
Pubmed	Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex.	KPNA5 HSPA2 HSPA8	2.66e-06	15	64	3	10964507
Pubmed	Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.	SF3B3 HSPA1L HSPA2 HSPA8	3.08e-06	54	64	4	31792442
Pubmed	TonEBP/NFAT5 stimulates transcription of HSP70 in response to hypertonicity.	NFAT5 HSPA2	3.33e-06	2	64	2	12138186
Pubmed	Rho GTPase Activating Protein 24 (ARHGAP24) Regulates the Anti-Cancer Activity of Sorafenib Against Breast Cancer MDA-MB-231 Cells via the Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathway.	ARHGAP24 STAT3	3.33e-06	2	64	2	30499465
Pubmed	Association of Met439Thr substitution in heat shock protein 70 gene with postoperative atrial fibrillation and serum HSP70 protein levels.	HSPA1L HSPA8	3.33e-06	2	64	2	17934269
Pubmed	FilGAP, a Rho/Rho-associated protein kinase-regulated GTPase-activating protein for Rac, controls tumor cell migration.	ARHGAP24 ROCK1	3.33e-06	2	64	2	23097497
Pubmed	SCR: novel human suppressors of cdc2/cdc13 mutants of Schizosaccharomyces pombe harbour motifs for RNA binding proteins.	RBMS1 RBMS2	3.33e-06	2	64	2	8041632
Pubmed	STAT3 and MITF cooperatively induce cellular transformation through upregulation of c-fos expression.	MITF STAT3	3.33e-06	2	64	2	14737107
Pubmed	Polymorphisms in genes coding for HSP-70 are associated with gastric cancer and duodenal ulcer in a population at high risk of gastric cancer in Costa Rica.	HSPA1L HSPA2	3.33e-06	2	64	2	24051039
Pubmed	Structures and comparison of genomic and complementary DNAs of mouse MSSP, a c-Myc binding protein.	RBMS1 RBMS2	3.33e-06	2	64	2	10639566
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	SF3B3 MAGED1 COPB2 HSPA1L HSPA2 HSPA8 ARAF	4.75e-06	363	64	7	25036637
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	TNPO1 UBE2K SF3B3 MAGED1 RBMS2 COPB2 ROCK1 COPS3 HSPA1L PAIP1 HSPA8 STAU1	6.41e-06	1367	64	12	32687490
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	KPNA5 TNPO1 SF3B3 ROCK1 HSPA1L HSPA2 HSPA8	7.58e-06	390	64	7	17643375
Pubmed	The DNA sequence of the human X chromosome.	UBQLN2 MAGED1 GRIA3 DMD SAGE2P ARAF MBNL3	9.99e-06	407	64	7	15772651
Pubmed	Identification and characterization of ARHGAP24 and ARHGAP25 genes in silico.	ARHGAP22 ARHGAP24	9.99e-06	3	64	2	15254788
Pubmed	STAT3 signaling controls satellite cell expansion and skeletal muscle repair.	DMD STAT3	9.99e-06	3	64	2	25194572
Pubmed	Low Six4 and Six5 gene dosage improves dystrophic phenotype and prolongs life span of mdx mice.	SIX4 DMD	9.99e-06	3	64	2	27224259
Pubmed	FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling.	ARHGAP24 ROCK1	9.99e-06	3	64	2	16862148
Pubmed	Knockout of STAT3 in skeletal muscle does not prevent high-fat diet-induced insulin resistance.	DMD STAT3	9.99e-06	3	64	2	26266089
Pubmed	Association of hsp70 polymorphisms with risk of noise-induced hearing loss in Chinese automobile workers.	HSPA1L HSPA2	9.99e-06	3	64	2	17009596
Pubmed	HSPA1A, HSPA2, and HSPA8 Are Potential Molecular Biomarkers for Prognosis among HSP70 Family in Alzheimer's Disease.	HSPA2 HSPA8	9.99e-06	3	64	2	36246562
Pubmed	STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration.	DMD STAT3	9.99e-06	3	64	2	27524611
Pubmed	Identifying a common molecular mechanism for inhibition of MITF and STAT3 by PIAS3.	MITF STAT3	9.99e-06	3	64	2	16368885
Pubmed	Interplay between MITF, PIAS3, and STAT3 in mast cells and melanocytes.	MITF STAT3	9.99e-06	3	64	2	15572665
Pubmed	RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation.	ROCK1 STAT3	9.99e-06	3	64	2	29678906
Pubmed	The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities.	HSPA1L HSPA2 HSPA8	1.03e-05	23	64	3	21231916
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	KPNA5 TNPO1 VPS13D MAGED1 SZT2 COPB2 PEX1 ARAF	1.52e-05	606	64	8	36538041
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	TNPO1 HNF1B SF3B3 COPB2 MED14 ZNF622 NFAT5 HSPA8 ARAF NDUFS4 STAU1	1.57e-05	1247	64	11	27684187
Pubmed	Genetic factors determine extent of bone loss in inflammatory bowel disease.	HSPA1L HSPA2	2.00e-05	4	64	2	11040178
Pubmed	Variations in HSP70 genes associated with noise-induced hearing loss in two independent populations.	HSPA1L HSPA2	2.00e-05	4	64	2	18813331
Pubmed	MiR-599 regulates LPS-mediated apoptosis and inflammatory responses through the JAK2/STAT3 signalling pathway via targeting ROCK1 in human umbilical vein endothelial cells.	ROCK1 STAT3	2.00e-05	4	64	2	32248560
Pubmed	STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway.	MITF STAT3	2.00e-05	4	64	2	33323974
Pubmed	Association analysis of heat shock protein 70 gene polymorphisms in schizophrenia.	HSPA1L HSPA8	2.00e-05	4	64	2	18299791
Pubmed	Analysis of the human VPS13 gene family.	VPS13D VPS13B	2.00e-05	4	64	2	15498460
Pubmed	Tid1 isoforms are mitochondrial DnaJ-like chaperones with unique carboxyl termini that determine cytosolic fate.	HSPA8 STAT3	2.00e-05	4	64	2	16531398
Pubmed	WWP2 is an E3 ubiquitin ligase for PTEN.	HSPA1L HSPA2 HSPA8	2.10e-05	29	64	3	21532586
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	DMD PARP14 HSPA1L HSPA2 HSPA8	2.51e-05	187	64	5	26460568
Pubmed	ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.	TNPO1 RNF214 MAGED1 RBMS1 RBMS2 STAU1	2.54e-05	315	64	6	26777405
Pubmed	RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.	TNPO1 HSPA2 PAIP1 HSPA8	2.58e-05	92	64	4	23055941
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	SF3B3 UBQLN2 MAGED1 HSPA1L HSPA2 HSPA8 ARAF	2.76e-05	477	64	7	31300519
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	RBMS1 GLI3 RBMS2 PEX1 NFAT5 STAU1	2.82e-05	321	64	6	32098917
Pubmed	Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility.	UBE2K UBQLN2 MAGED1	3.12e-05	33	64	3	17558393
Pubmed	Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway.	DMD STAT3	3.32e-05	5	64	2	22606352
Pubmed	Structure and expression of a human gene coding for a 71 kd heat shock 'cognate' protein.	HSPA2 HSPA8	3.32e-05	5	64	2	3037489
Pubmed	A sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathy.	GLI3 MITF	3.32e-05	5	64	2	18397875
Pubmed	HDJC9, a novel human type C DnaJ/HSP40 member interacts with and cochaperones HSP70 through the J domain.	HSPA1L HSPA8	3.32e-05	5	64	2	17182002
Pubmed	Circular RNA FOXP1 promotes tumor progression and Warburg effect in gallbladder cancer by regulating PKLR expression.	RBMS2 DMD HSPA8 STAU1	3.87e-05	102	64	4	31623628
Pubmed	Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation.	KPNA5 CEP78 ARAF	4.06e-05	36	64	3	35379950
Pubmed	TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A.	COPS3 HSPA2 HSPA8	4.42e-05	37	64	3	29531219
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	KPNA5 SF3B3 RBMS3 RBMS1 COPB2 PEX1 HSPA1L HSPA2 HSPA8 STAU1	4.59e-05	1153	64	10	29845934
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	TNPO1 SF3B3 COPB2 ROCK1 JMJD1C HSPA8 STAT3 STAU1	4.60e-05	708	64	8	39231216
Pubmed	A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.	MAGED1 COPS3 HSPA1L	4.79e-05	38	64	3	18247557
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	SF3B3 MAGED1 COPB2 TMOD2 HSPA1L HSPA2 HSPA8 STAU1	4.88e-05	714	64	8	28302793
Pubmed	Genetic aspects of the hsp70 multigene family in vertebrates.	HSPA1L HSPA8	4.98e-05	6	64	2	7988674
Pubmed	Association analysis of HLA-class II and class III gene polymorphisms in the susceptibility to mediterranean visceral leishmaniasis.	HSPA1L HSPA2	4.98e-05	6	64	2	11334675
Pubmed	Which FGF ligands are involved in lens induction?	HNF1B MITF	4.98e-05	6	64	2	19913010
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	TNPO1 VPS13D TENM4 MBD5 PAIP1 JMJD1C STAT3	5.77e-05	536	64	7	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	TNPO1 VPS13D TENM4 MBD5 PAIP1 JMJD1C STAT3	5.91e-05	538	64	7	10512203
Pubmed	Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.	HNF1B RBMS1 GCKR	6.03e-05	41	64	3	20889853
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SF3B3 RBMS1 RBMS2 HSPA2 JMJD1C HSPA8 TASOR2 STAU1 NPAT	6.03e-05	954	64	9	36373674
Pubmed	Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.	MAGED1 RBMS1 DMD HSPA8 ARAF NDUFS4 TASOR2 S100PBP	6.38e-05	742	64	8	26871637
Pubmed	Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey.	HSPA1L HSPA2 HSPA8 NDUFS4	6.61e-05	117	64	4	18977241
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	SF3B3 UBQLN2 MAGED1 COPB2 ZNF622 HSPA1L PAIP1 HSPA8 STAU1	6.91e-05	971	64	9	33306668
Pubmed	A mutation in the nuclear pore complex gene Tmem48 causes gametogenesis defects in skeletal fusions with sterility (sks) mice.	HSPA1L HSPA2	6.96e-05	7	64	2	24045954
Pubmed	Messenger RNA expression of heat shock proteins (HSPs) during ocular development.	HSPA1L HSPA8	6.96e-05	7	64	2	8974842
Pubmed	A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.	HSPA1L HSPA2 HSPA8 NDUFS4	7.06e-05	119	64	4	17601350
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	TNPO1 VPS13D SF3B3 HSPA1L HSPA8	7.44e-05	235	64	5	30258100
Pubmed	A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.	GRIA3 MBD5 NFAT5	7.46e-05	44	64	3	32492419
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TNPO1 SF3B3 MAGED1 ZNF622 HSPA1L HSPA2 HSPA8 VPS13B NDUFS4 STAU1 NPAT	7.76e-05	1487	64	11	33957083
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	ROCK1 COPS3 SIX4 HSPA1L HSPA2 JMJD1C	9.26e-05	398	64	6	35016035
Pubmed	Function and regulation of heat shock factor 2 during mouse embryogenesis.	HSPA2 HSPA8	9.27e-05	8	64	2	9122205
Pubmed	Cytosolic p120-catenin regulates growth of metastatic lobular carcinoma through Rock1-mediated anoikis resistance.	ROCK1 STAT3	9.27e-05	8	64	2	21747168
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	KMT2B ASH1L	9.27e-05	8	64	2	23130995
Pubmed	A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity.	HSPA2 HSPA8	9.27e-05	8	64	2	30591555
Pubmed	Blocking nuclear import of pre-integration complex: an emerging anti-HIV-1 drug discovery paradigm.	KPNA5 TNPO1	9.27e-05	8	64	2	20015032
Pubmed	Plasticity in the Glucagon Interactome Reveals Novel Proteins That Regulate Glucagon Secretion in α-TC1-6 Cells.	GRIA3 DMD HSPA2 HSPA8 VPS13B	9.40e-05	247	64	5	30713523
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	ARHGAP22 SF3B3 COPS3 SIX4 NFAT5 HSPA2 HSPA8	9.75e-05	583	64	7	29844126
Pubmed	A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors.	HSPA1L HSPA2 HSPA8	1.10e-04	50	64	3	23703321
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	SF3B3 COPB2 ASH1L COPS3 HSPA1L HSPA2 HSPA8 STAU1	1.14e-04	807	64	8	30575818
Pubmed	HIV-1 nuclear import: in search of a leader.	KPNA5 TNPO1	1.19e-04	9	64	2	10525473
Pubmed	HIV-1 infection requires a functional integrase NLS.	KPNA5 TNPO1	1.19e-04	9	64	2	11389849
Pubmed	Viral protein R regulates nuclear import of the HIV-1 pre-integration complex.	KPNA5 TNPO1	1.19e-04	9	64	2	9463369
Pubmed	Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import.	KPNA5 TNPO1	1.19e-04	9	64	2	12414950
Pubmed	Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein.	KPNA5 TNPO1	1.19e-04	9	64	2	10366569
Pubmed	HIV-1 nuclear import: in search of a leader.	KPNA5 TNPO1	1.19e-04	9	64	2	9366553
Pubmed	Chromosomal localization of five murine HSP70 gene family members: Hsp70-1, Hsp70-2, Hsp70-3, Hsc70t, and Grp78.	HSPA1L HSPA2	1.19e-04	9	64	2	8486356
Pubmed	Two nuclear localization signals in the HIV-1 matrix protein regulate nuclear import of the HIV-1 pre-integration complex.	KPNA5 TNPO1	1.19e-04	9	64	2	10860744
Pubmed	Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import.	KPNA5 TNPO1	1.19e-04	9	64	2	12368302
Pubmed	Transportin 3 and importin α are required for effective nuclear import of HIV-1 integrase in virus-infected cells.	KPNA5 TNPO1	1.19e-04	9	64	2	21326825
Pubmed	Exocrine glands and the Chievitz organ of some mouse mutants.	GLI3 MITF	1.19e-04	9	64	2	5088022
Pubmed	Cellular distribution and karyophilic properties of matrix, integrase, and Vpr proteins from the human and simian immunodeficiency viruses.	KPNA5 TNPO1	1.19e-04	9	64	2	11035935
Interaction	RNF43 interactions	TNPO1 MAGED1 GLI3 RBMS2 HSPA1L HSPA2 PAIP1 JMJD1C HSPA8 VPS13B	5.64e-07	427	61	10	int:RNF43
Interaction	EEF1AKMT3 interactions	PEX1 SIX4 PARP14 HSPA1L HSPA2 HSPA8 ARAF VPS13B STAT3	1.40e-06	364	61	9	int:EEF1AKMT3
Interaction	DNAJA1 interactions	TNPO1 UBQLN2 ASXL3 COPS3 MBD5 HSPA1L HSPA2 HSPA8 ARAF STAU1	4.13e-06	533	61	10	int:DNAJA1
Interaction	PCBP1 interactions	HNF1B SF3B3 UBQLN2 ASXL3 ZNF622 MBD5 HSPA1L HSPA2 HSPA8 STAT3 STAU1	4.72e-06	671	61	11	int:PCBP1
Interaction	DAZL interactions	RNF214 MAGED1 RBMS3 RBMS1 RBMS2 PAIP1	5.01e-06	145	61	6	int:DAZL
Interaction	CYP2W1 interactions	HSPA1L HSPA2 HSPA8	1.17e-05	15	61	3	int:CYP2W1
Interaction	HELZ interactions	RNF214 SF3B3 MAGED1 RBMS1 RBMS2 PAIP1 STAU1	1.23e-05	257	61	7	int:HELZ
Interaction	PRODH interactions	HSPA1L HSPA2 HSPA8	1.44e-05	16	61	3	int:PRODH
Interaction	PRRC2B interactions	RNF214 HNF1B UBQLN2 RBMS1 GLI3 HSPA8 STAU1	1.49e-05	265	61	7	int:PRRC2B
Interaction	DCAF4 interactions	MAGED1 RBMS1 RBMS2 ASH1L ZNF622 COPS3 PARP14 STAU1	1.76e-05	378	61	8	int:DCAF4
Interaction	SMAP2 interactions	RNF214 UBQLN2 MAGED1 RBMS1 RBMS2 STAU1	2.27e-05	189	61	6	int:SMAP2
Interaction	QKI interactions	TNPO1 RBMS1 RBMS2 MED14 HSPA2 HSPA8	2.34e-05	190	61	6	int:QKI
Interaction	UNK interactions	RNF214 SF3B3 RBMS1 COPB2 MED14 COPS3 STAU1 NPAT	3.04e-05	408	61	8	int:UNK
Interaction	ARMC5 interactions	SF3B3 MAGED1 HSPA1L HSPA2 HSPA8 ARAF	3.21e-05	201	61	6	int:ARMC5
Interaction	ZNF488 interactions	MAGED1 HSPA2 HSPA8	3.38e-05	21	61	3	int:ZNF488
Interaction	DNAJA2 interactions	TNPO1 UBQLN2 MAGED1 ASXL3 HSPA1L HSPA2 HSPA8 ARAF STAU1	3.44e-05	542	61	9	int:DNAJA2
Interaction	KPNB1 interactions	KPNA5 TNPO1 ARHGAP24 SF3B3 UBQLN2 ASXL3 HSPA8 ARAF STAU1	3.54e-05	544	61	9	int:KPNB1
Interaction	CNOT1 interactions	RNF214 RBMS1 GLI3 MED14 PAIP1 HSPA8 STAU1	3.68e-05	305	61	7	int:CNOT1
Interaction	ELP4 interactions	SF3B3 HSPA1L HSPA2 HSPA8	3.72e-05	62	61	4	int:ELP4
Interaction	CNOT3 interactions	RNF214 RBMS1 GLI3 MED14 PAIP1 HSPA8	3.79e-05	207	61	6	int:CNOT3
Interaction	RBMS1 interactions	RNF214 UBQLN2 MAGED1 RBMS1 RBMS2 STAU1	3.79e-05	207	61	6	int:RBMS1
Interaction	SNX20 interactions	HSPA2 HSPA8 VPS13B	3.90e-05	22	61	3	int:SNX20
Interaction	SNX21 interactions	PEX1 HSPA2 HSPA8 VPS13B	5.05e-05	67	61	4	int:SNX21
Interaction	CDRT15P3 interactions	PEX1 HSPA2 HSPA8	5.10e-05	24	61	3	int:CDRT15P3
Interaction	PPP1R12A interactions	ARHGAP24 ASH1L ROCK1 COPS3 HSPA2 HSPA8 STAU1	5.19e-05	322	61	7	int:PPP1R12A
Interaction	RUVBL1 interactions	TNPO1 HNF1B UBQLN2 ASXL3 COPS3 HSPA1L HSPA8 ARAF STAU1	5.44e-05	575	61	9	int:RUVBL1
Interaction	CCDC117 interactions	HSPA1L HSPA2 HSPA8	6.53e-05	26	61	3	int:CCDC117
Interaction	ABHD15 interactions	HSPA1L HSPA2 HSPA8	7.33e-05	27	61	3	int:ABHD15
Interaction	PUM2 interactions	RNF214 RBMS1 RBMS2 PAIP1 STAU1	7.49e-05	144	61	5	int:PUM2
Interaction	RUVBL2 interactions	TNPO1 HNF1B UBQLN2 ASXL3 TMOD2 HSPA1L PAIP1 HSPA8 STAU1	9.22e-05	616	61	9	int:RUVBL2
Interaction	HNRNPA1 interactions	TNPO1 UBE2K UBQLN2 RBMS1 ASXL3 COPB2 ROCK1 HSPA2 HSPA8 ARAF STAU1	1.10e-04	945	61	11	int:HNRNPA1
Interaction	NYNRIN interactions	UBQLN2 HSPA8 STAU1	1.12e-04	31	61	3	int:NYNRIN
Interaction	COPG2 interactions	ARHGAP24 UBQLN2 MAGED1 COPB2 STAU1	1.13e-04	157	61	5	int:COPG2
Interaction	HNRNPC interactions	KPNA5 SF3B3 UBQLN2 RBMS2 COPB2 COPS3 PAIP1 HSPA8 STAU1	1.15e-04	634	61	9	int:HNRNPC
Interaction	SEC23A interactions	ARHGAP24 UBQLN2 ASXL3 COPB2 HSPA8 STAU1	1.20e-04	255	61	6	int:SEC23A
Interaction	SMG5 interactions	RNF214 UBQLN2 RBMS1 STAU1	1.22e-04	84	61	4	int:SMG5
Interaction	FOXP1 interactions	HNF1B RBMS2 DMD NFAT5 HSPA8 STAU1	1.23e-04	256	61	6	int:FOXP1
Interaction	ATP5F1A interactions	ARHGAP24 UBQLN2 ASXL3 COPS3 HSPA1L HSPA2 HSPA8 NDUFS4 STAU1	1.23e-04	640	61	9	int:ATP5F1A
Interaction	VARS1 interactions	TNPO1 TMOD2 COPS3 PAIP1 HSPA8 STAU1	1.33e-04	260	61	6	int:VARS1
Interaction	URGCP interactions	HSPA1L HSPA2 HSPA8	1.35e-04	33	61	3	int:URGCP
Interaction	N4BP2 interactions	RNF214 SF3B3 RBMS1 STAU1	1.53e-04	89	61	4	int:N4BP2
Interaction	MKRN2 interactions	RNF214 UBE2K UBQLN2 RBMS1 GLI3 RBMS2 PAIP1	1.58e-04	385	61	7	int:MKRN2
Interaction	TADA2B interactions	ARHGAP24 SF3B3 MED14 STAU1	1.60e-04	90	61	4	int:TADA2B
Interaction	KPNA2 interactions	TNPO1 ARHGAP22 UBQLN2 MAGED1 ASXL3 MBD5 HSPA8 STAU1	1.63e-04	519	61	8	int:KPNA2
Interaction	TWIST1 interactions	KPNA5 GLI3 HSPA8 STAT3 STAU1	1.64e-04	170	61	5	int:TWIST1
Interaction	UBAP2 interactions	RNF214 RBMS1 HSPA2 STAU1 NPAS2	1.64e-04	170	61	5	int:UBAP2
Interaction	RC3H2 interactions	RNF214 UBE2K SF3B3 MAGED1 CEP78 RBMS1 HSPA8 STAU1 NPAT	1.68e-04	667	61	9	int:RC3H2
Interaction	HGS interactions	SF3B3 UBQLN2 MAGED1 ROCK1 HSPA2 HSPA8 TASOR2 NPAS2	1.71e-04	523	61	8	int:HGS
Interaction	METTL21A interactions	HSPA1L HSPA2 HSPA8	1.75e-04	36	61	3	int:METTL21A
Interaction	ZNF703 interactions	UBQLN2 HSPA2 HSPA8 STAU1	1.81e-04	93	61	4	int:ZNF703
Interaction	POU2F1 interactions	ARHGAP24 HSPA2 HSPA8 STAT3 NPAT	1.87e-04	175	61	5	int:POU2F1
Interaction	NPEPPS interactions	TNPO1 ARHGAP24 ZNF622 HSPA8 STAU1	1.97e-04	177	61	5	int:NPEPPS
Interaction	TNRC6A interactions	TNPO1 KMT2B RBMS1 GLI3 MED14 STAU1	1.99e-04	280	61	6	int:TNRC6A
Interaction	CLEC11A interactions	UBQLN2 CEP78 ASH1L ARAF	2.05e-04	96	61	4	int:CLEC11A
Interaction	LRRC8E interactions	ARHGAP24 DMD HSPA2 HSPA8	2.05e-04	96	61	4	int:LRRC8E
Interaction	TNRC6B interactions	RNF214 MAGED1 RBMS1 GLI3 PAIP1 STAU1	2.07e-04	282	61	6	int:TNRC6B
Interaction	PUM1 interactions	RNF214 MAGED1 RBMS1 RBMS2 HSPA8 STAU1	2.28e-04	287	61	6	int:PUM1
Interaction	EDRF1 interactions	HSPA1L HSPA2 HSPA8 NPAS2	2.31e-04	99	61	4	int:EDRF1
Interaction	ZNRD2 interactions	SF3B3 UBQLN2 CEP78 PARP14 ARAF STAT3	2.32e-04	288	61	6	int:ZNRD2
Interaction	HSPA1L interactions	UBQLN2 COPS3 HSPA1L HSPA2 HSPA8 STAU1	2.37e-04	289	61	6	int:HSPA1L
Interaction	PABPC1 interactions	ARHGAP24 SF3B3 UBQLN2 RBMS1 RBMS2 PAIP1 HSPA8 ARAF STAU1	2.38e-04	699	61	9	int:PABPC1
Interaction	SLC25A23 interactions	HSPA1L HSPA2 HSPA8	2.41e-04	40	61	3	int:SLC25A23
Interaction	TRPM6 interactions	ARHGAP24 STAU1	2.49e-04	8	61	2	int:TRPM6
Interaction	C1orf94 interactions	UBQLN2 MAGED1 RFX2 HSPA8	2.68e-04	103	61	4	int:C1orf94
Interaction	MCM5 interactions	ARHGAP24 SF3B3 UBQLN2 HSPA1L HSPA2 HSPA8 STAU1	2.69e-04	420	61	7	int:MCM5
Interaction	TUBB4B interactions	TNPO1 UBQLN2 ASXL3 COPB2 ZNF622 COPS3 HSPA8 ARAF	2.73e-04	560	61	8	int:TUBB4B
Interaction	DNAJB1 interactions	UBQLN2 HSPA1L HSPA2 HSPA8 STAU1 NPAT	2.74e-04	297	61	6	int:DNAJB1
Interaction	SOX2 interactions	TNPO1 HNF1B MAGED1 RBMS1 GLI3 RBMS2 MITF COPS3 SIX4 JMJD1C HSPA8 ITIH1 STAU1	2.74e-04	1422	61	13	int:SOX2
Interaction	FAM120C interactions	RNF214 MAGED1 RBMS1 RBMS2 STAU1	2.81e-04	191	61	5	int:FAM120C
Interaction	EIF4ENIF1 interactions	RNF214 SF3B3 RBMS1 GLI3 RBMS2 STAU1	2.89e-04	300	61	6	int:EIF4ENIF1
Interaction	FCSK interactions	SF3B3 HSPA1L HSPA8	2.99e-04	43	61	3	int:FCSK
Interaction	RAVER1 interactions	ARHGAP24 UBQLN2 RBMS1 HSPA2 STAU1	3.02e-04	194	61	5	int:RAVER1
Interaction	IPO7 interactions	TNPO1 ARHGAP24 HSPA1L HSPA8 ARAF STAU1	3.10e-04	304	61	6	int:IPO7
Interaction	SLC25A5 interactions	UBQLN2 ASXL3 MBD5 HSPA8 ARAF NDUFS4 STAU1	3.14e-04	431	61	7	int:SLC25A5
Interaction	GADL1 interactions	HSPA2 HSPA8	3.20e-04	9	61	2	int:GADL1
Interaction	ADAD2 interactions	HSPA2 HSPA8	3.20e-04	9	61	2	int:ADAD2
Interaction	CCNI2 interactions	HSPA1L HSPA8	3.20e-04	9	61	2	int:CCNI2
Interaction	ADNP interactions	KPNA5 COPS3 HSPA2 HSPA8 STAU1	3.39e-04	199	61	5	int:ADNP
Interaction	NIPBL interactions	KPNA5 HNF1B SF3B3 HSPA8 STAU1	3.39e-04	199	61	5	int:NIPBL
Interaction	H3C1 interactions	KPNA5 HNF1B UBE2K KMT2B ASH1L MED14 MBD5 JMJD1C HSPA8 STAU1	3.44e-04	901	61	10	int:H3C1
Interaction	TUBB interactions	ARHGAP24 SF3B3 UBQLN2 ASXL3 COPB2 HSPA2 HSPA8 ARAF STAU1	3.45e-04	735	61	9	int:TUBB
Interaction	HSP90AA1 interactions	ARHGAP24 SF3B3 UBQLN2 ASXL3 COPS3 HSPA1L HSPA2 HSPA8 ARAF ITIH1 STAT3 NPAS2	3.46e-04	1263	61	12	int:HSP90AA1
Interaction	HIF1A interactions	KPNA5 MITF MED14 HSPA1L HSPA2 HSPA8 STAT3	3.61e-04	441	61	7	int:HIF1A
Interaction	PABPC4 interactions	UBQLN2 RBMS1 HSPA2 PAIP1 HSPA8 ARAF STAU1	3.66e-04	442	61	7	int:PABPC4
Interaction	THRAP3 interactions	TNPO1 HNF1B SF3B3 HSPA8 ARAF TASOR2 STAU1	3.71e-04	443	61	7	int:THRAP3
Interaction	PRPF40A interactions	UBE2K SF3B3 UBQLN2 KMT2B HSPA1L HSPA8 STAU1	3.86e-04	446	61	7	int:PRPF40A
Interaction	TRIM38 interactions	HSPA1L HSPA2 HSPA8	3.89e-04	47	61	3	int:TRIM38
Interaction	DHDH interactions	RNF214 HSPA2 HSPA8	3.89e-04	47	61	3	int:DHDH
Interaction	YAP1 interactions	HNF1B SF3B3 UBQLN2 KMT2B COPB2 MED14 NFAT5 HSPA1L HSPA2 JMJD1C HSPA8	3.96e-04	1095	61	11	int:YAP1
Interaction	CCDC142 interactions	HSPA1L HSPA8	3.99e-04	10	61	2	int:CCDC142
Interaction	SOHLH1 interactions	HSPA1L HSPA2 HSPA8 VPS13B	4.09e-04	115	61	4	int:SOHLH1
Interaction	NR1I3 interactions	MED14 HSPA2 HSPA8	4.14e-04	48	61	3	int:NR1I3
Interaction	FBXO7 interactions	KPNA5 SF3B3 UBQLN2 MAGED1 MITF TMOD2 COPS3 MBD5	4.23e-04	598	61	8	int:FBXO7
Interaction	CREBBP interactions	HNF1B GLI3 MITF GRIA3 HSPA8 STAT3 NPAS2 NPAT	4.27e-04	599	61	8	int:CREBBP
Interaction	HDAC1 interactions	HNF1B KMT2B GLI3 COPS3 JMJD1C HSPA8 ARAF STAT3 STAU1 S100PBP NPAT	4.38e-04	1108	61	11	int:HDAC1
Interaction	THSD4 interactions	GLI3 HSPA2 HSPA8	4.67e-04	50	61	3	int:THSD4
Interaction	RBMX interactions	VPS13D SF3B3 UBQLN2 ASXL3 PAIP1 HSPA8 STAU1	4.70e-04	461	61	7	int:RBMX
Interaction	G6PD interactions	ARHGAP24 ZNF622 DMD HSPA8 STAU1	4.73e-04	214	61	5	int:G6PD
Interaction	ZC3H7A interactions	RNF214 MAGED1 RBMS1 STAT3 STAU1	4.83e-04	215	61	5	int:ZC3H7A
Interaction	CCK interactions	UBQLN2 CCKAR	4.87e-04	11	61	2	int:CCK
GeneFamily	Heat shock 70kDa proteins	HSPA1L HSPA2 HSPA8	1.16e-05	17	48	3	583
GeneFamily	Armadillo repeat containing\|Importins	KPNA5 TNPO1	1.03e-03	18	48	2	596
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGAP22 ARHGAP24 RALGPS2 ROCK1	2.15e-03	206	48	4	682
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2B ASH1L	3.67e-03	34	48	2	487
GeneFamily	Olfactory receptors, family 1	OR1D5 OR1D4	5.05e-03	40	48	2	147
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP22 ARHGAP24	7.80e-03	50	48	2	721
GeneFamily	X-linked mental retardation\|Angiotensin receptors	GRIA3 DMD	8.73e-03	53	48	2	103
GeneFamily	RNA binding motif containing	RBMS3 RBMS1 RBMS2	1.89e-02	213	48	3	725
Coexpression	CAFFAREL_RESPONSE_TO_THC_8HR_5_DN	HSPA1L HSPA2 HSPA8	2.73e-06	12	62	3	M2260
Coexpression	DIAZ_CHRONIC_MYELOGENOUS_LEUKEMIA_UP	UBE2K SF3B3 UBQLN2 RBMS1 COPB2 PEX1 COPS3 ODC1 PAIP1 ARAF NDUFS4 STAT3 STAU1 NPAT	3.72e-06	1399	62	14	M535
Coexpression	HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_DN	HSPA1L HSPA2 HSPA8	1.88e-05	22	62	3	M1191
Coexpression	MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN	PEX1 HSPA1L JMJD1C HSPA8 STAU1 NPAS2	4.46e-05	272	62	6	M15123
Coexpression	HOLLERN_SOLID_NODULAR_BREAST_TUMOR_DN	RBMS3 GLI3 RALGPS2	4.89e-05	30	62	3	M743
Coexpression	LAKE_ADULT_KIDNEY_C11_THIN_ASCENDING_LIMB	ARHGAP24 TENM4 RBMS1 NFAT5 VPS13B	5.05e-05	169	62	5	M39230
Coexpression	SHEN_SMARCA2_TARGETS_UP	TNPO1 UBQLN2 MED14 ROCK1 PAIP1 TASOR2 STAU1	6.78e-05	429	62	7	M29
Coexpression	HEVNER_CORTEX_CAUDAL_SUBVENTRICULAR_ZONE	TENM4 CCKAR STAT3	1.08e-04	39	62	3	MM441
Coexpression	GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN	KPNA5 RBMS1 MED14 PARP14 MBNL3	1.09e-04	199	62	5	M3175
Coexpression	GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_6H_DN	MED14 ZNF622 PARP14 JMJD1C MBNL3	1.12e-04	200	62	5	M6404
Coexpression	GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN	TNPO1 ZNF14 UBE2K SZT2 HSPA2	1.12e-04	200	62	5	M3127
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000	UBE2K RBMS3 ASXL3 ASH1L TMOD2 NFAT5 PAIP1 S100PBP	3.96e-06	330	60	8	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000	TENM4 SZT2 RBMS3 RBMS1 ASXL3 GLI3 ZFP57 GRIA3 HSPA1L HSPA8 MBNL3	1.83e-05	831	60	11	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_1000	SZT2 MED14 PEX1 SIX4 MBD5 NFAT5 HSPA8 ARAF NDUFS4 S100PBP	5.97e-05	779	60	10	gudmap_developingKidney_e15.5_Cap mesenchyme_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	VPS13D TENM4 RBMS3 ASXL3 ASH1L GRIA3 NFAT5 JMJD1C MBNL3 STAT3	6.71e-05	790	60	10	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	TENM4 RBMS3 ASXL3 ASH1L GRIA3 ROCK1 NFAT5 JMJD1C MBNL3 STAT3	7.52e-05	801	60	10	gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	TENM4 CEP78 RBMS3 RBMS1 ASXL3 GLI3 ZFP57 GRIA3 HSPA8 MBNL3	9.80e-05	827	60	10	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2	ARHGAP24 TENM4 KMT2B SZT2 RBMS3 RBMS1 ASXL3 GLI3 GRIA3 DMD VPS13B STAT3	1.20e-04	1208	60	12	facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500	TENM4 RBMS3 RBMS1 ASXL3 GRIA3 HSPA8 MBNL3	1.84e-04	423	60	7	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500
CoexpressionAtlas	DevelopingKidney_e15.5_Proximal Tubules_emap-28005_top-relative-expression-ranked_1000	HNF1B ARHGAP24 MITF PEX1 GRIA3 NFAT5 HSPA8 ARAF CCKAR	2.60e-04	758	60	9	gudmap_developingKidney_e15.5_Proximal Tubules_1000
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP24 MAGED1 RBMS3 JMJD1C HSPA8 STAT3	3.08e-07	195	62	6	4d63e0dca30ae57960459d2fbcba09122273e37b
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP24 MAGED1 RBMS3 JMJD1C HSPA8 STAT3	3.08e-07	195	62	6	661af601a3561fe3aacf2444ad7b8927fa88b48a
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP24 TENM4 RBMS3 ODC1 DMD STAT3	3.27e-07	197	62	6	5bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	SZT2 ASXL3 SIX4 JMJD1C TASOR2	2.07e-06	149	62	5	768877bade04ca0321593b8470b5011ad8270431
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD9 TMOD2 GRIA3 DMD S100PBP	4.81e-06	177	62	5	426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L ODC1 DMD JMJD1C STAT3	5.96e-06	185	62	5	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	VPS13D MED14 NFAT5 VPS13B NPAT	6.12e-06	186	62	5	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP24 TENM4 RBMS3 ODC1 DMD	6.28e-06	187	62	5	69b47f00598d647e2a99427ebddf42c339428e47
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ASH1L PARP14 NFAT5 JMJD1C TASOR2	6.44e-06	188	62	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP24 ODC1 DMD HSPA8 STAT3	7.89e-06	196	62	5	97ac47daf5bb07fa5dda3976e1ae402750f959b5
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBMS3 ASH1L JMJD1C HSPA8 STAT3	7.89e-06	196	62	5	151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCell	COVID-19_Mild-PLT_4\|COVID-19_Mild / Disease Group and Platelet Clusters	UBE2K COPS3 JMJD1C NDUFS4 NPAT	8.28e-06	198	62	5	3d8c33dba759df0974aeb2b9a6b5167ae7a18e1f
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	KPNA5 ARHGAP22 UBE2K GCKR	3.46e-05	132	62	4	a1fda8c5287168c4f159203ed27cadfb4ce1b131
ToppCell	mild_COVID-19-B_cell\|World / disease group, cell group and cell class (v2)	GLI3 RALGPS2 NPAS2 NPAT	4.73e-05	143	62	4	4698cc877dda9b1ef7d6f18c9adc869ef791b1d8
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD9 GRIA3 DMD S100PBP	1.08e-04	177	62	4	1dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TENM4 GRIA3 ODC1 DMD	1.23e-04	183	62	4	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	ASH1L PARP14 NFAT5 JMJD1C	1.23e-04	183	62	4	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP24 RALGPS2 ODC1 PARP14	1.28e-04	185	62	4	e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP22 HNF1B ARHGAP24 GLI3	1.34e-04	187	62	4	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	human_hepatoblastoma-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	RBMS1 DMD MBD5 MBNL3	1.34e-04	187	62	4	f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	RBMS1 RFX2 STAT3 NPAS2	1.48e-04	192	62	4	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ASH1L MBD5 JMJD1C VPS13B	1.48e-04	192	62	4	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KPNA5 ZNF14 CEP78 VPS13B	1.51e-04	193	62	4	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	TENM4 RBMS3 GLI3 DMD	1.51e-04	193	62	4	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ARHGAP24 RALGPS2 PARP14 JMJD1C	1.54e-04	194	62	4	ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell	PBMC-Control\|PBMC / Compartment, Disease Groups and Clusters	ARHGAP22 ARHGAP24 TENM4 HSPA8	1.57e-04	195	62	4	3cc4afa5f68f28336310d5f80a082cb8d98a5679
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP24 RALGPS2 PARP14 JMJD1C	1.57e-04	195	62	4	481989d2e5bd2582da3d86b0155c4d6615317067
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP24 RALGPS2 PARP14 JMJD1C	1.57e-04	195	62	4	6108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCell	(4)_B_follicular\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ARHGAP24 RALGPS2 ODC1 PARP14	1.57e-04	195	62	4	defffb7a58a30d2745d2f93dc4aca7be1b53c4ef
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP24 DMD MBD5 VPS13B	1.60e-04	196	62	4	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-GC_B_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARHGAP24 RALGPS2 ODC1 PARP14	1.60e-04	196	62	4	d08f6143d148a897efacc854e4306455a9a9868c
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MITF ODC1 DMD HSPA8	1.60e-04	196	62	4	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-immature_B_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	RALGPS2 ODC1 HSPA2 HSPA8	1.60e-04	196	62	4	9a6e4eea19348a6e3379d3b872456ab6280cb74f
ToppCell	COVID_vent-Lymphocytic-Plasma_cell-IgA_Plasmablast\|COVID_vent / Disease condition, Lineage, Cell class and subclass	MAGED1 COPB2 RALGPS2 ODC1	1.63e-04	197	62	4	99fe44ef42c65d24fe64947fd5bf6d91b9a4b2c3
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TENM4 ASXL3 GLI3 NPAS2	1.63e-04	197	62	4	1e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell	mild_COVID-19-B_intermediate\|World / disease group, cell group and cell class (v2)	ARHGAP24 RALGPS2 ODC1 DMD	1.63e-04	197	62	4	e909b898b7458071f176b6c04356ea3540589153
ToppCell	facs-Diaphragm-Limb_Muscle-3m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGED1 JMJD1C HSPA8 STAT3	1.63e-04	197	62	4	b0e2ea81308bce289cb7cbea0e27de1d01afeed2
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CEP78 ASH1L ROCK1 HSPA8	1.66e-04	198	62	4	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP24 DMD MBD5 VPS13B	1.66e-04	198	62	4	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CEP78 ASH1L PARP14 VPS13B	1.69e-04	199	62	4	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	severe-B_intermediate\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ARHGAP24 RALGPS2 ODC1 DMD	1.69e-04	199	62	4	17283d75a2a900369f63ed02996e7ede97f46140
ToppCell	Macroglial-Astrocytes-SLC14A1\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ARHGAP24 RBMS3 GLI3 RFX2	1.73e-04	200	62	4	16f468217427921fa18c6d078ffa990eb019b257
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Astrocyte\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	RBMS1 SIX4 RFX2 ARAF	1.73e-04	200	62	4	b9bd6c4381c92bfc1bfff9aa778a62a41d08f1ef
ToppCell	Macroglial-Astrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ARHGAP24 RBMS3 GLI3 RFX2	1.73e-04	200	62	4	941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCell	Macroglial-Astrocytes-SLC14A1---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ARHGAP24 RBMS3 GLI3 RFX2	1.73e-04	200	62	4	d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCell	Macroglial-Astrocytes-SLC14A1----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ARHGAP24 RBMS3 GLI3 RFX2	1.73e-04	200	62	4	f861509b54185d89931db64da1b9d81986cc7938
ToppCell	Macroglial-Astrocytes-SLC14A1--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ARHGAP24 RBMS3 GLI3 RFX2	1.73e-04	200	62	4	0442894c39eec69850c090957a5dc7bcecd21e04
ToppCell	severe-B_intermediate\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ARHGAP24 RALGPS2 ODC1 DMD	1.73e-04	200	62	4	6d0ac3d00400dd5657ee266f7b885381bf790ce1
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	ROCK1 ODC1 PARP14 STAT3	1.73e-04	200	62	4	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Macroglial-Astrocytes-SLC14A1-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ARHGAP24 RBMS3 GLI3 RFX2	1.73e-04	200	62	4	01819446deeab9054f5cfe889d53bb49d137dbc0
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ASH1L ROCK1 PARP14 JMJD1C	1.73e-04	200	62	4	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	(53)_Lymphoid_DC\|World / shred on Cell_type and subtype	ARHGAP22 ASXL3 DMD ITIH1	2.01e-04	208	62	4	30212cfacad94a7cc562a69efa73a31259851515
Disease	cholelithiasis	HNF1B GCKR NFAT5 JMJD1C VPS13B	1.29e-06	88	63	5	EFO_0004799
Disease	Neonatal diabetes mellitus	HNF1B ZFP57 STAT3	2.06e-05	25	63	3	C0158981
Disease	serum urea measurement	TNPO1 HNF1B ASH1L GCKR NFAT5	6.17e-05	195	63	5	EFO_0009795
Disease	myotonic dystrophy type 1 (implicated_via_orthology)	SIX4 MBNL3	6.69e-05	6	63	2	DOID:11722 (implicated_via_orthology)
Disease	gallstones	HNF1B GCKR NFAT5 JMJD1C	8.56e-05	108	63	4	EFO_0004210
Disease	DIABETES MELLITUS, PERMANENT NEONATAL	HNF1B STAT3	9.36e-05	7	63	2	C1833104
Disease	trait in response to apixaban	TENM4 RBMS3 GLI3 DMD	1.09e-04	115	63	4	OBA_2050328
Disease	omega-6:omega-3 polyunsaturated fatty acid ratio	RBMS3 GCKR JMJD1C	1.69e-04	50	63	3	EFO_0010732
Disease	glutamine measurement, amino acid measurement	TNPO1 RBMS2	2.44e-04	11	63	2	EFO_0005134, EFO_0009768
Disease	serum albumin measurement	TNPO1 HNF1B UBE2K RBMS2 GCKR JMJD1C ITIH1	2.64e-04	592	63	7	EFO_0004535
Disease	phosphatidylcholine 34:4 measurement	GCKR MBD5	2.92e-04	12	63	2	EFO_0010378
Disease	1-myristoyl-2-arachidonoyl-GPC (14:0/20:4) measurement	ROCK1 GCKR	2.92e-04	12	63	2	EFO_0800453
Disease	breast carcinoma	ZNF14 ARHGAP24 RBMS1 ZFP57 ASH1L DMD PAIP1 JMJD1C TASOR2	2.99e-04	1019	63	9	EFO_0000305
Disease	level of Phosphatidylcholine (16:1_18:1) in blood serum	ROCK1 GCKR	3.45e-04	13	63	2	OBA_2045082
Disease	histidine measurement	TNPO1 RBMS2 GCKR	3.86e-04	66	63	3	EFO_0009769
Disease	blood urea nitrogen measurement	TNPO1 HNF1B GCKR DMD MBD5 NFAT5	4.06e-04	452	63	6	EFO_0004741
Disease	liver volume	GCKR JMJD1C	4.63e-04	15	63	2	EFO_0600048
Disease	empathy measurement	TENM4 RBMS3 OR1D5 OR1D4	4.86e-04	170	63	4	EFO_0009183
Disease	T-Cell Lymphoma	ASXL3 STAT3	5.28e-04	16	63	2	C0079772
Disease	Bipolar Disorder	TENM4 GRIA3 MBD5 ITIH1 CCKAR NPAS2	5.39e-04	477	63	6	C0005586
Disease	plasma beta-amyloid 1-40 measurement	RNF214 UBE2K	5.98e-04	17	63	2	EFO_0005659
Disease	pre-malignant neoplasm (biomarker_via_orthology)	GLI3 STAT3	5.98e-04	17	63	2	DOID:0060071 (biomarker_via_orthology)
Disease	level of Phosphatidylcholine (14:0_18:2) in blood serum	ROCK1 GCKR	5.98e-04	17	63	2	OBA_2045063
Disease	alanine measurement	TNPO1 SF3B3 GCKR	8.37e-04	86	63	3	EFO_0009765
Disease	cognitive function measurement	ARHGAP22 RNF214 TENM4 SZT2 RBMS1 GLI3 ZFP57 JMJD1C STAU1 NPAS2	8.66e-04	1434	63	10	EFO_0008354
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	ASXL3 GCKR NFAT5 JMJD1C	8.93e-04	200	63	4	EFO_0004611, EFO_0020945
Disease	prothrombin time measurement	GCKR JMJD1C	9.18e-04	21	63	2	EFO_0008390
Disease	level of Phosphatidylcholine (16:1_18:2) in blood serum	ROCK1 GCKR	9.18e-04	21	63	2	OBA_2045083
Disease	gamma-glutamylglutamine measurement	TNPO1 RBMS2	1.01e-03	22	63	2	EFO_0021138
Disease	glutamine measurement	TNPO1 RBMS2 GCKR	1.19e-03	97	63	3	EFO_0009768
Disease	periodontal measurement	RBMS3 ASH1L	1.20e-03	24	63	2	EFO_0007780
Disease	alpha fetoprotein measurement	UBE2K GCKR JMJD1C	1.29e-03	100	63	3	EFO_0010583
Disease	sodium measurement	GCKR NFAT5 JMJD1C	1.41e-03	103	63	3	EFO_0009282
Disease	L lactate dehydrogenase measurement	TENM4 GCKR	1.41e-03	26	63	2	EFO_0004808
Disease	forced expiratory volume	ARHGAP24 TDRD9 RBMS1 ZFP57 RALGPS2 NFAT5 JMJD1C	1.44e-03	789	63	7	EFO_0004314
Disease	chloride measurement	GCKR NFAT5	1.76e-03	29	63	2	EFO_0009284
Disease	neuroimaging measurement	TNPO1 ARHGAP22 KMT2B SZT2 GLI3 MITF RALGPS2 JMJD1C	1.92e-03	1069	63	8	EFO_0004346
Disease	Malignant neoplasm of breast	KPNA5 MED14 SIX4 DMD RFX2 ARAF VPS13B STAT3	1.97e-03	1074	63	8	C0006142
Disease	cholesteryl esters to total lipids in large LDL percentage	GCKR JMJD1C	2.00e-03	31	63	2	EFO_0022249
Disease	intelligence, self reported educational attainment	JMJD1C STAU1 NPAS2	2.03e-03	117	63	3	EFO_0004337, EFO_0004784

Protein segments in the cluster

Peptide	Gene	Start	Entry
VVSMQAFQAAQFVNP	ASH1L	1861	Q9NR48
KAMDQEITVNPQFVQ	COPS3	391	Q9UNS2
MQIVINPKDNNQFAS	COPB2	146	P35606
EPKQNALGQMQNIQF	CEP78	586	Q5JTW2
NLVPFTKNNNQTANM	CCKAR	181	P32238
VDAAQMPQEAQKIQS	DMD	1401	P11532
QKPFTQLAAQKMQVQ	ASXL3	2131	Q9C0F0
QNAQMPVQNFADSSN	ASXL3	2191	Q9C0F0
NQQQFIFQQQEAPMD	KPNA5	521	O15131
SGVQAQMAKQQEQDP	RBMS1	126	P29558
GVQAQMAKQQEQDPT	RBMS2	121	Q15434
GVQAQMAKQQEQDPT	RBMS3	126	Q6XE24
LVQDSNVQMFLQQPA	NPAS2	536	Q99743
NFQDPNAFAVEKQMV	NPAT	231	Q14207
NAITMQPQNVQGLSK	GLI3	56	P10071
PTADTQTQNVNQAKM	MAGED1	191	Q9Y5V3
FAPQNLTNMNKNVVF	ITIH1	281	P19827
TNKQNLQVGNFPTMN	JMJD1C	1936	Q15652
NITGFQIVNNENPMV	GRIA3	266	P42263
AKNQVAMNPTNTIFD	HSPA2	56	P54652
NQFNNQPMAKVQSHS	CSNKA2IP	36	A0A1B0GTH6
AAKNQVAMNPQNTVF	HSPA1L	56	P34931
IDQQQQQKVAASMPL	KMT2B	806	Q9UMN6
PMNNLQTNTVAQEAF	NFAT5	1146	O94916
QQNSESAMAKPQVVV	PAIP1	106	Q9H074
QEMFNKTPNVVQLLQ	MED14	856	O60244
QPQSNNSQENMKVAS	OR5AK3P	261	Q8NH89
MFNQKAELTNQGPQF	GCKR	371	Q14397
MAQKNIQVSPEIFQF	PARP14	531	Q460N5
NKMSVQNLATVFGPN	ARHGAP24	281	Q8N264
SQPTAEQAQAFKNEM	ARAF	341	P10398
NNLIQQKTAAAMFAQ	MBNL3	86	Q9NUK0
NNNPMACLFQNFQVR	MBD5	1006	Q9P267
NNNFQQTVSDKNMPD	S100PBP	216	Q96BU1
VPARNNMQSGVNNTK	NDUFS4	81	O43181
NAFKNMQSKVVPLDN	PEX1	271	O43933
QVSQIKYAANNGVQM	ODC1	116	P11926
AACQSNKQQVPTNLM	RALGPS2	566	Q86X27
IGDAAKNQVAMNPTN	HSPA8	51	P11142
KNQVAMNPTNTVFDA	HSPA8	56	P11142
NTIPKMLVNFQSQNK	OR1D4	76	P47884
NTIPKMLVNFQSQNK	OR1D5	76	P58170
AQQPFMAAVTQLQNS	HNF1B	496	P35680
KVATMLQQQYDPQSQ	SZT2	196	Q5T011
NVDFQKQTVDPMQVS	TDRD9	871	Q8NDG6
TNAMSDFPQQVIQTK	RFX2	486	P48378
LVFSQLMPVNQNAQV	SIX4	576	Q9UIU6
NKMSVQNLATVFGPN	ARHGAP22	301	Q7Z5H3
FPQCNKAQMTNILQQ	RNF214	566	Q8ND24
MAQNQASVLKNQAPV	ZFP57	256	Q9NU63
QAAQFMQQRVPVSQT	MITF	81	O75030
MSQVQVQVQNPSAAL	STAU1	1	O95793
MENNQPQFNNVLSTV	SAGE2P	221	A6NJ88
NMLTNNPKNVNFFTK	STAT3	481	P40763
MFKNNNPISNSQDIK	TENM4	2451	Q6N022
QFNSMEPNKQKNVSE	SF3B3	1181	Q15393
KTLAQAMLNNAQPDQ	TNPO1	626	Q92973
EMEPVQQAEKTNFQN	ROCK1	1211	Q13464
QDAVVANQYKQNPEM	UBE2K	126	P61086
DQPMQNFQKTSEAQA	VPS13B	3771	Q7Z7G8
DAMNAAIQQAIKAQP	ZNF622	126	Q969S3
PVGQDNFTQVQQMQV	TASOR2	1461	Q5VWN6
SESGPNQQFIQQMVQ	UBQLN2	551	Q9UHD9
NPTNVEISLQQMKAN	TMOD2	181	Q9NZR1
QMPNVNINKETFTGA	ZNF14	86	P17017
IKNVSMQNAVNEPVQ	VPS13D	176	Q5THJ4
NANPEANMNISQIIS	LIPK	26	Q5VXJ0