Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessinorganic diphosphate transport

ENPP1 ENPP3 ABCC6

5.17e-075783GO:0030505
GeneOntologyCellularComponentcell surface

IL17A PXDN ANK3 MS4A1 ENPP1 ENPP3 TNFRSF14 LRP2 HRG ADGRE5 ADAM17 LTF ADGRE1 ITGB3

9.82e-0511118214GO:0009986
HumanPhenoStippled calcification of the shoulder

ENPP1 ABCC6

2.91e-052282HP:0003836
HumanPhenoMyocardial calcification

ENPP1 ABCC6

2.91e-052282HP:0006690
HumanPhenoMedial calcification of medium-sized arteries

ENPP1 ABCC6

2.91e-052282HP:0012457
HumanPhenoCortical nephrocalcinosis

ENPP1 ABCC6

2.91e-052282HP:0012409
HumanPhenoStippled calcification of the elbow

ENPP1 ABCC6

2.91e-052282HP:0003941
HumanPhenoRecurrent spontaneous abortion

ENPP1 ABCC6 F12

3.17e-0512283HP:0200067
HumanPhenoExcessive wrinkled skin

ENPP1 GORAB ABCC6 ADAMTSL2

7.78e-0543284HP:0007392
HumanPhenoMiscarriage

ENPP1 ABCC6 F12 RYR1

9.32e-0545284HP:0005268
HumanPhenoAbnormal delivery

ENPP1 SCN4A ITGB3 ABCC6 F12 RYR1

1.08e-04145286HP:0001787
HumanPhenoAbnormal hip joint morphology

ERCC1 TELO2 ENPP1 GORAB SCN4A KAT6B TET3 ABCC6 RYR1 ADAMTSL2

1.64e-044902810HP:0001384
HumanPhenoCalcification of the auricular cartilage

ENPP1 ABCC6

1.74e-044282HP:0005103
HumanPhenoCoronary artery calcification

ENPP1 ABCC6

1.74e-044282HP:0001717
HumanPhenoLarge artery calcification

ENPP1 ABCC6

1.74e-044282HP:0012455
HumanPhenoMedial arterial calcification

ENPP1 ABCC6

1.74e-044282HP:0012456
HumanPhenoPeriarticular calcification

ENPP1 ABCC6

1.74e-044282HP:0025477
HumanPhenoMedial calcification of large arteries

ENPP1 ABCC6

1.74e-044282HP:0004966
HumanPhenoWeak pulse

ENPP1 ABCC6

1.74e-044282HP:0032553
HumanPhenoAbnormal synovial membrane morphology

ERCC1 TELO2 ENPP1 GORAB SCN4A KAT6B TET3 ABCC6 RYR1 ADAMTSL2

2.05e-045032810HP:0005262
HumanPhenoHepatic calcification

ENPP1 ABCC6

2.88e-045282HP:0006559
HumanPhenoHip contracture

TELO2 SCN4A KAT6B RYR1

3.27e-0462284HP:0003273
HumanPhenoOsteomalacia

ENPP1 ABCC6 ADAMTSL2

3.98e-0427283HP:0002749
HumanPhenoAbnormal calcification of the carpal bones

ENPP1 ABCC6

4.31e-046282HP:0009164
HumanPhenoPremature skin wrinkling

ENPP1 GORAB ABCC6 ADAMTSL2

4.67e-0468284HP:0100678
DomainTIL_dom

FCGBP LRP2 MUC6

2.47e-0514783IPR002919
DomainNUC

ENPP1 ENPP3

2.55e-046782SM00477
DomainEndonuclease_NS

ENPP1 ENPP3

2.55e-046782SM00892
DomainDNA/RNA_non-sp_Endonuclease

ENPP1 ENPP3

2.55e-046782IPR001604
Domain-

ENPP1 ENPP3

2.55e-0467823.40.570.10
DomainEndonuclease_NS

ENPP1 ENPP3

2.55e-046782PF01223
DomainExtracellular_endonuc_su_A

ENPP1 ENPP3

2.55e-046782IPR020821
DomainE-NPP

ENPP1 ENPP3

3.57e-047782IPR024873
DomainEGF

SCARF1 FCGBP LRP2 ADGRE5 ADGRE1 F12

4.49e-04235786SM00181
DomainSomatomedin_B

ENPP1 ENPP3

4.74e-048782PF01033
DomainSO

ENPP1 ENPP3

6.08e-049782SM00201
DomainEGF-like_dom

SCARF1 FCGBP LRP2 ADGRE5 ADGRE1 F12

6.09e-04249786IPR000742
DomainVWF_dom

FCGBP PXDN MUC6

7.15e-0442783IPR001007
DomainSomatomedin_B_dom

ENPP1 ENPP3

7.58e-0410782IPR001212
DomainSMB_1

ENPP1 ENPP3

7.58e-0410782PS00524
DomainSMB_2

ENPP1 ENPP3

7.58e-0410782PS50958
DomainPhosphodiest

ENPP1 ENPP3

7.58e-0410782PF01663
DomainPhosphodiest/P_Trfase

ENPP1 ENPP3

7.58e-0410782IPR002591
DomainEGF-like_CS

SCARF1 LRP2 ADAM17 ADGRE1 ITGB3 F12

7.79e-04261786IPR013032
DomainTIL

FCGBP MUC6

1.11e-0312782PF01826
DomainC8

FCGBP MUC6

1.11e-0312782PF08742
DomainUnchr_dom_Cys-rich

FCGBP MUC6

1.30e-0313782IPR014853
DomainC8

FCGBP MUC6

1.30e-0313782SM00832
DomainEGF_CA

LRP2 ADGRE5 ADGRE1 F12

1.70e-03122784SM00179
DomainEGF-like_Ca-bd_dom

LRP2 ADGRE5 ADGRE1 F12

1.81e-03124784IPR001881
DomainVWD

FCGBP MUC6

1.99e-0316782SM00216
DomainVWF_type-D

FCGBP MUC6

1.99e-0316782IPR001846
DomainVWFD

FCGBP MUC6

1.99e-0316782PS51233
DomainVWD

FCGBP MUC6

1.99e-0316782PF00094
DomainEGF_extracell

SCARF1 LRP2 ITGB3

2.02e-0360783IPR013111
DomainEGF_2

SCARF1 LRP2 ITGB3

2.02e-0360783PF07974
DomainVWC_out

FCGBP MUC6

2.81e-0319782SM00215
DomainEGF_3

SCARF1 LRP2 ADGRE5 ADGRE1 F12

3.03e-03235785PS50026
DomainTNFR_c6

TNFRSF8 TNFRSF14

3.77e-0322782PF00020
DomainPHD

KMT2E KAT6B PHF13

3.81e-0375783PF00628
DomainGrowth_fac_rcpt_

SCARF1 LRP2 ADGRE5 ADGRE1

4.14e-03156784IPR009030
DomainEGF_1

SCARF1 LRP2 ADGRE1 ITGB3 F12

4.28e-03255785PS00022
DomainZnf_PHD-finger

KMT2E KAT6B PHF13

4.41e-0379783IPR019787
DomainEGF_2

SCARF1 LRP2 ADGRE1 ITGB3 F12

5.04e-03265785PS01186
DomainTNFR

TNFRSF8 TNFRSF14

5.24e-0326782SM00208
DomaincEGF

LRP2 ADGRE1

5.24e-0326782IPR026823
DomaincEGF

LRP2 ADGRE1

5.24e-0326782PF12662
DomainSANT_dom

MIER2 NCOR1

5.24e-0326782IPR017884
DomainEGF_CA

LRP2 ADGRE5 ADGRE1

5.59e-0386783PF07645
DomainSANT

MIER2 NCOR1

6.07e-0328782PS51293
Pubmed

Genomic structure and promoter analysis of the ecto-phosphodiesterase I gene (PDNP3) expressed in glial cells.

ENPP1 ENPP3

5.76e-06284210524196
Pubmed

Ectopic Calcification and Hypophosphatemic Rickets: Natural History of ENPP1 and ABCC6 Deficiencies.

ENPP1 ABCC6

5.76e-06284234355424
Pubmed

Diadenosine 5',5''-(boranated)polyphosphonate analogues as selective nucleotide pyrophosphatase/phosphodiesterase inhibitors.

ENPP1 ENPP3

5.76e-06284221090681
Pubmed

Molecular cloning and chromosomal localization of PD-Ibeta (PDNP3), a new member of the human phosphodiesterase I genes.

ENPP1 ENPP3

5.76e-0628429344668
Pubmed

Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-1 (E-NPP1/PC-1) and -3 (E-NPP3/CD203c/PD-Ibeta/B10/gp130(RB13-6)) in inflammatory and neoplastic bile duct diseases.

ENPP1 ENPP3

5.76e-06284215072822
Pubmed

Oral administration of pyrophosphate inhibits connective tissue calcification.

ENPP1 ABCC6

5.76e-06284228701330
Pubmed

Genetic heterogeneity of pseudoxanthoma elasticum: the Chinese signature profile of ABCC6 and ENPP1 mutations.

ENPP1 ABCC6

5.76e-06284225615550
Pubmed

Generalized Arterial Calcification of Infancy

ENPP1 ABCC6

5.76e-06284225392903
Pubmed

Identification of hydrolytically stable and selective P2Y(1) receptor agonists.

ENPP1 ENPP3

5.76e-06284218760862
Pubmed

Genetic modulation of nephrocalcinosis in mouse models of ectopic mineralization: the Abcc6(tm1Jfk) and Enpp1(asj) mutant mice.

ENPP1 ABCC6

5.76e-06284224732453
Pubmed

Plasma PPi Deficiency Is the Major, but Not the Exclusive, Cause of Ectopic Mineralization in an Abcc6-/- Mouse Model of PXE.

ENPP1 ABCC6

5.76e-06284228652107
Pubmed

Ectonucleotide pyrophosphatase/phosphodiesterase activity in Neuro-2a neuroblastoma cells: changes in expression associated with neuronal differentiation.

ENPP1 ENPP3

5.76e-06284224947519
Pubmed

Histidine-rich glycoprotein binds factor XIIa with high affinity and inhibits contact-initiated coagulation.

HRG F12

5.76e-06284221304106
Pubmed

Generalized arterial calcification of infancy and pseudoxanthoma elasticum can be caused by mutations in either ENPP1 or ABCC6.

ENPP1 ABCC6

5.76e-06284222209248
Pubmed

Interleukin (IL)-17-producing pathogenic T lymphocytes co-express CD20 and are depleted by rituximab in primary Sjögren's syndrome: a pilot study.

IL17A MS4A1

5.76e-06284226814615
Pubmed

TET3 boosts hepatocyte autophagy and impairs non-alcoholic fatty liver disease by increasing ENPP1 promoter hypomethylation.

ENPP1 TET3

5.76e-06284238582229
Pubmed

Primary decidual zone formation requires Scribble for pregnancy success in mice.

LTF PGR

1.73e-05384231780662
Pubmed

Progesterone receptor B recruits a repressor complex to a half-PRE site of the estrogen receptor alpha gene promoter.

NCOR1 PGR

1.73e-05384219147702
Pubmed

Uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success.

LTF PGR

1.73e-05384229934619
Pubmed

CD30 is required for activation of a unique subset of interleukin-17A-producing γδ T cells in innate immunity against Mycobacterium bovis Bacillus Calmette-Guerin infection.

IL17A TNFRSF8

1.73e-05384223918785
Pubmed

Differential mechanisms of inorganic pyrophosphate production by plasma cell membrane glycoprotein-1 and B10 in chondrocytes.

ENPP1 ENPP3

1.73e-05384210513816
Pubmed

Endometrial epithelial ARID1A is critical for uterine gland function in early pregnancy establishment.

LTF PGR

1.73e-05384233222288
Pubmed

The uterine epithelial loss of Pten is inefficient to induce endometrial cancer with intact stromal Pten.

LTF PGR

1.73e-05384230142194
Pubmed

Scribble promotes alveologenesis in the pregnant mammary gland for milk production.

LTF PGR

1.73e-05384232213656
Pubmed

Generation of Mouse for Conditional Expression of Forkhead Box A2.

LTF PGR

1.73e-05384229546371
Pubmed

Tridimensional visualization reveals direct communication between the embryo and glands critical for implantation.

LTF PGR

1.73e-05384229426931
Pubmed

METTL16-SENP3-LTF axis confers ferroptosis resistance and facilitates tumorigenesis in hepatocellular carcinoma.

LTF METTL16

1.73e-05384239218945
Pubmed

The EZH2-PRC2-H3K27me3 axis governs the endometrial cell cycle and differentiation for blastocyst invasion.

LTF PGR

1.73e-05384237198149
Pubmed

Retinoblastoma protein promotes uterine epithelial cell cycle arrest and necroptosis for embryo invasion.

LTF PGR

1.73e-05384233399260
Pubmed

Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin time.

HRG F12

1.73e-05384220303064
Pubmed

Genetic variants in cardiac calcification in Northern Sweden.

ENPP1 ABCC6

1.73e-05384230985656
Pubmed

JAM-C induces endothelial cell permeability through its association and regulation of {beta}3 integrins.

AFDN ITGB3

3.45e-05484219461049
Pubmed

Crosstalk between PKCα and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium.

LTF PGR

3.45e-05484230021163
Pubmed

Differential roles of uterine epithelial and stromal STAT3 coordinate uterine receptivity and embryo attachment.

LTF PGR

3.45e-05484232968170
Pubmed

Genetics in arterial calcification: lessons learned from rare diseases.

ENPP1 ABCC6

3.45e-05484223122642
Pubmed

Conditional inactivation of TACE by a Sox9 promoter leads to osteoporosis and increased granulopoiesis via dysregulation of IL-17 and G-CSF.

IL17A ADAM17

3.45e-05484219201862
Pubmed

Whole chromosome aneuploidy in the brain of Bub1bH/H and Ercc1-/Δ7 mice.

ERCC1 ADGRE1

3.45e-05484226681803
Pubmed

Inflammatory Th17 Cells Express Integrin αvβ3 for Pathogenic Function.

IL17A ITGB3

3.45e-05484227452457
Pubmed

Different Cre systems induce differential microRNA landscapes and abnormalities in the female reproductive tracts of Dgcr8 conditional knockout mice.

LTF PGR

3.45e-05484233496365
Pubmed

Lactoferrin-iCre: a new mouse line to study uterine epithelial gene function.

LTF PGR

3.45e-05484224823394
Pubmed

Extracellular pyrophosphate metabolism and calcification in vascular smooth muscle.

ENPP1 ENPP3

5.74e-05584221490328
Pubmed

Dysbiosis and Staphylococcus aureus Colonization Drives Inflammation in Atopic Dermatitis.

IL17A ADAM17

5.74e-05584225902485
Pubmed

Dynamic expression of TET1, TET2, and TET3 dioxygenases in mouse and human placentas throughout gestation.

ADGRE1 TET3

5.74e-05584229108636
Pubmed

STAT3 accelerates uterine epithelial regeneration in a mouse model of decellularized uterine matrix transplantation.

LTF PGR

5.74e-05584227358915
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

NCOR1 USF3 ANK3 KMT2E FOXJ3 ITGB3 WNK2

8.40e-0543084735044719
Pubmed

SOX17 regulates uterine epithelial-stromal cross-talk acting via a distal enhancer upstream of Ihh.

LTF PGR

8.59e-05684230356064
Pubmed

Physical mapping of EMR1 and CD97 in human Chromosome 19 and assignment of Cd97 to mouse Chromosome 8 suggest an ancient genomic duplication.

ADGRE5 ADGRE1

8.59e-05684210501980
Pubmed

The EGF-TM7 family: a postgenomic view.

ADGRE5 ADGRE1

8.59e-05684214647991
Pubmed

Uterine glands impact embryo survival and stromal cell decidualization in mice.

ADGRE1 PGR

8.59e-05684234547143
Pubmed

Role of thrombophilic gene polymorphisms in branch retinal vein occlusion.

ITGB3 F12

8.59e-05684216157382
Pubmed

Mandibular dysmorphology due to abnormal embryonic osteogenesis in FGFR2-related craniosynostosis mice.

ENPP1 ITGB3

1.20e-04784231064775
Pubmed

Polycomb subunit BMI1 determines uterine progesterone responsiveness essential for normal embryo implantation.

LTF PGR

1.20e-04784229202468
Pubmed

The transient appearance of zipper-like actin superstructures during the fusion of osteoclasts.

AFDN ITGB3

1.60e-04884222349694
Pubmed

Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase.

ENPP1 ABCC6

1.60e-04884228592560
Pubmed

Transforming growth factors beta 1, beta 2, and beta 3 messenger RNA and protein expression in mouse uterus and vagina during estrogen-induced growth: a comparison to other estrogen-regulated genes.

LTF PGR

1.60e-0488427819129
Pubmed

New genetic associations detected in a host response study to hepatitis B vaccine.

IL17A FCGBP MS4A1 TNFRSF8 TNFRSF14 HRG ADGRE5 LTF ITGB3

1.70e-0482484920237496
Pubmed

Nuclear monomeric integrin αv in cancer cells is a coactivator regulated by thyroid hormone.

NCOR1 ITGB3

2.05e-04984223640055
Pubmed

Catalytic activity of ADAM8, ADAM15, and MDC-L (ADAM28) on synthetic peptide substrates and in ectodomain cleavage of CD23.

TNFRSF8 ADAM17

2.05e-04984212777399
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

GABRE EP400P1 USF3 PXDN SHC2 ANK3 NACC2 NFIC KAT6B FOXJ3 TET3 WNK2

2.37e-041489841228611215
Pubmed

Genetic linkage analysis and homology relationships of genes located on human chromosome 11q.

MS4A1 PGR

2.56e-04108421679745
Pubmed

Evolutionary history and genome organization of DUF1220 protein domains.

NBPF8 NBPF12

2.56e-041084222973535
Pubmed

Role of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 protein.

AFDN ITGB3

2.56e-041084222027834
Pubmed

Cochaperone immunophilin FKBP52 is critical to uterine receptivity for embryo implantation.

LTF PGR

2.56e-041084216176985
Pubmed

Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues.

IL17A TNFRSF8

2.56e-041084232647184
Pubmed

Implantation failure in mice with a disruption in Phospholipase C beta 1 gene: lack of embryonic attachment, aberrant steroid hormone signalling and defective endocannabinoid metabolism.

LTF PGR

2.56e-041084223295235
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

NCOR1 GORAB KMT2E TET3 WNK2

2.60e-0423384537704626
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TELO2 LMTK2 ICE1 CACHD1 KAT6B FOXJ3 WNK2

2.99e-0452984714621295
Pubmed

A forward genetic screen in mice identifies mutants with abnormal cortical patterning.

LRP2 DNAAF1

3.13e-041184223968836
Pubmed

ADAM17 Regulates p75NTR-Mediated Fibrinolysis and Nerve Remyelination.

ADAM17 ADGRE1

3.75e-041284235110388
Pubmed

The transcriptional repressor Blimp1/PRDM1 regulates the maternal decidual response in mice.

ADGRE1 PGR

4.42e-041384232493987
Pubmed

Analysis of BCL6-interacting proteins by tandem mass spectrometry.

NCOR1 TNFRSF8 OSBPL1A

4.64e-046284316147992
Pubmed

The DNA sequence and biology of human chromosome 19.

FCGBP SHC2 NFIC ADGRE5 RYR1

6.39e-0428484515057824
Pubmed

Conditional deletion of Msx homeobox genes in the uterus inhibits blastocyst implantation by altering uterine receptivity.

LTF PGR

6.77e-041684222100262
Pubmed

Study of 18 functional hemostatic polymorphisms in mucocutaneous bleeding disorders.

ITGB3 F12

6.77e-041684220532885
Pubmed

A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly.

EP400P1 ANK3

6.77e-041684224535457
Pubmed

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.

AFAP1L2 AFDN ICE1 CSMD3 MUC6

7.36e-0429384531741433
Pubmed

Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland.

LTF ADGRE1

7.66e-041784228576768
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

NBPF8 NBPF12 LTF UNC79

7.84e-0417084423314748
Pubmed

Apoptotic cells in mouse blastocysts are eliminated by neighbouring blastomeres.

SCARF1 ITGB3

8.60e-041884233927296
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOR1 WDHD1 ZDBF2 DNAAF1 FOXJ3 ABCC6 RYR1

9.04e-0463884731182584
Pubmed

HIF2α in the uterine stroma permits embryo invasion and luminal epithelium detachment.

LTF PGR

9.60e-041984229911998
Pubmed

Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase.

LTF PGR

9.60e-041984228424251
Pubmed

Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers.

ERCC1 RYR1

9.60e-04198428432525
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF8 NBPF12

1.17e-032184216079250
Pubmed

Maternal hypervitaminosis D reduces fetal bone mass and mineral acquisition and leads to neonatal lethality.

ENPP1 ENPP3

1.17e-032184223895994
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

TNFRSF14 LRP2 ADGRE5 WNK2 RYR1

1.23e-0332984517474147
Pubmed

Identification of single nucleotide polymorphisms in the tumor necrosis factor (TNF) and TNF receptor superfamily in the Korean population.

TNFRSF8 TNFRSF14

1.29e-032284215301860
Pubmed

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.

SPHKAP RYR1

1.29e-032284226494785
Pubmed

BMP/SMAD1/5 Signaling in the Endometrial Epithelium Is Essential for Receptivity and Early Pregnancy.

LTF PGR

1.67e-032584235383354
Pubmed

Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis.

RAPGEF3 AFDN

1.80e-032684226212757
Pubmed

Family-based analysis of candidate genes for polycystic ovary syndrome.

ENPP1 FEM1A

1.95e-032784220200332
Pubmed

Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.

NCOR1 LRP2

1.95e-032784228167773
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

NCOR1 LMTK2 FOXJ3

2.08e-0310484310470851
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

ZSCAN29 PXDN KAT6B FEM1A FOXJ3

2.08e-0337184515747579
Pubmed

Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development.

LRP2 ADGRE1

2.09e-032884228847650
Pubmed

EGFL7 is expressed in bone microenvironment and promotes angiogenesis via ERK, STAT3, and integrin signaling cascades.

LTF PGR

2.24e-032984224909139
Pubmed

Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms.

LTF PGR

2.24e-032984224971735
Pubmed

Human gingiva transcriptome during wound healing.

PXDN ADGRE1 ITGB3

2.25e-0310784328005267
Pubmed

TRIM28 modulates nuclear receptor signaling to regulate uterine function.

LTF PGR

2.40e-033084237528140
Pubmed

iRhom2 mutation leads to aberrant hair follicle differentiation in mice.

ADAM17 ADGRE1

2.40e-033084225546423
Cytoband19p13.3

MIER2 SHC2 NFIC SH2D3A ADGRE1 FEM1A

5.16e-0623784619p13.3
Cytoband6q27

RNASET2 AFDN FRMD1

1.45e-04558436q27
CytobandEnsembl 112 genes in cytogenetic band chr6q27

RNASET2 AFDN FRMD1

4.39e-0480843chr6q27
Cytoband2p25

PXDN ADAM17

4.97e-04188422p25
CytobandEnsembl 112 genes in cytogenetic band chr19p13

MIER2 SHC2 NFIC SH2D3A ADGRE5 ADGRE1 FEM1A

6.59e-04797847chr19p13
CytobandEnsembl 112 genes in cytogenetic band chr1p11

NBPF8 NBPF26

6.79e-0421842chr1p11
CytobandEnsembl 112 genes in cytogenetic band chr6q23

ENPP1 ENPP3 MTFR2

1.39e-03119843chr6q23
Cytoband5q35.1

INSYN2B SPDL1

2.23e-03388425q35.1
GeneFamilyNeuroblastoma breakpoint family

NBPF8 NBPF12 NBPF26

6.17e-0523613662
GeneFamilyCD molecules|Adhesion G protein-coupled receptors, subfamily E

ADGRE5 ADGRE1

1.11e-045612915
GeneFamilyADAM metallopeptidase domain containing|CD molecules

MS4A1 TNFRSF8 ENPP3 TNFRSF14 ADGRE5 ADAM17 ITGB3

3.51e-04394617471
GeneFamilyPHD finger proteins

KMT2E KAT6B PHF13

3.49e-039061388
GeneFamilyCD molecules|Tumor necrosis factor receptor superfamily|Death inducing signaling complex

TNFRSF8 TNFRSF14

4.29e-0329612782
ToppCellControl-B_intermediate-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

EP400P1 USF3 NBPF12 MS4A1 AFDN ICE1

7.65e-07167846948504367ecf58144d9dd74d2ec531358fc4b309
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

GABRE FCGBP ENPP3 SH2D3A LTF WNK2

9.39e-07173846d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCell367C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MIER2 TSGA13 ENPP1 AFDN ADGRE5 ADAMTSL2

1.77e-061938465c6b03d6d98aa873fda1a201d44a912246bb5a92
ToppCell367C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MIER2 TSGA13 ENPP1 AFDN ADGRE5 ADAMTSL2

1.77e-06193846d4b58eee97043b4337ec36c40f9af6499d864df9
ToppCellCOVID-19_Mild-Neu_1|World / 5 Neutrophil clusters in COVID-19 patients

USF3 ANK3 LRP2 UNC13C ADGRE1

3.96e-06125845e58c208b4355252ceabe04a468dd19a1f436182c
ToppCellTCGA-Thryoid|World / Sample_Type by Project: Shred V9

AFAP1L2 RAPGEF3 SCN4A PDE5A ITGB3

6.41e-061388458cbae2ec9a51712bed5b4e5f9f834ecccb6b7a47
ToppCellControl-B_intermediate-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

EP400P1 USF3 NBPF12 MS4A1 AFDN

7.89e-06144845984470ff6ddce4c743e2db78fa98dae055aaa273
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ENPP1 CDHR1 SH2D3A CACHD1 TTLL10

1.71e-05169845e9c0e0f4c421c7bdbf1a7e33002f3cf22ea307cb
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ENPP1 CDHR1 SH2D3A CACHD1 TTLL10

1.71e-05169845d375a1df1ecc938f66bad92e54b8cda26ca9c472
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ENPP1 CDHR1 SH2D3A CACHD1 TTLL10

1.71e-0516984558f805c0be507bd5fadc9ea3555032daabbc8ab8
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 UNC13C LTF CSMD3 UNC79

1.71e-0516984512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WDHD1 GORAB INSYN2B MTFR2 SPDL1

1.76e-0517084512aa9bdb18f3bf6da2a25984d08fe9497e5570ed
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PATL2 TNFRSF14 DNAAF1 ITGB3 F12

2.26e-05179845b7281160c84dd053a2981c9c76ea6cc6d2592cd5
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFAP1L2 ANK3 INSYN2B CSMD3 UNC79

2.51e-051838452cf36ad89584eb9f8b04de52a1b511b7f3527884
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFAP1L2 ANK3 INSYN2B CSMD3 UNC79

2.51e-0518384598fee6838acfaee5e2e449ba088764ec06b8bc57
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFAP1L2 ANK3 INSYN2B CSMD3 UNC79

2.64e-051858453d1353dbcb60e2531ef67e1bd218b7bc4d7c7c9b
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFAP1L2 ANK3 INSYN2B CSMD3 UNC79

2.64e-05185845995a8ddc3fd8e6879d8b5de8cbdefe232d34833b
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

NCOR1 ANK3 AFDN ICE1 KMT2E

2.64e-05185845857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 INSYN2B CSMD3 UNC79 WNK2

2.78e-0518784516e55d802fc4e71878305e61ad03806aabd59537
ToppCellCerebellum-Neuronal|Cerebellum / BrainAtlas - Mouse McCarroll V32

SHC2 INSYN2B ZDBF2 UNC79 PGR

2.78e-0518784561b9d6eb131a674598aa8409d7fa909c8765442d
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

ENPP1 ENPP3 OSBPL1A LRP2 PWWP3B

2.78e-05187845acd305475f3609800af0d7bc68d83ef41228080b
ToppCell18-Airway-Epithelial-Submucosal_gland|Airway / Age, Tissue, Lineage and Cell class

FCGBP ANK3 ENPP3 LTF WNK2

2.93e-05189845c1ea2dc44cf5340378e56e0ffc2e6f64e6c95a58
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MS4A1 ENPP1 AFDN PDE5A KMT2E

3.00e-05190845d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

ANK3 CFAP221 LRP2 CACHD1 ABCC6

3.08e-05191845276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ANK3 CFAP221 CACHD1 TTLL10 DNAAF1

3.23e-05193845ea345d34440b25f65358a53dc72831998d1c3620
ToppCellbackground-Cholangiocytes|background / Sample and Cell Type and Tumor Cluster (all cells)

ANK3 CFAP221 PWWP3B MUC6 WNK2

3.23e-051938459152241073dbe02ac2c11d86bec9b5b529196f6e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PDE5A INSYN2B UNC13C CSMD3 PGR

3.32e-051948455f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCellmyeloid-CD16+_Monocyte|myeloid / Lineage and Cell class

TNFRSF8 RNASET2 TNFRSF14 ADGRE5 ADGRE1

3.32e-05194845aeeadfeb01827dbc7de6576c76fb2e41a3c59247
ToppCellcellseq-Immune-Immune_Myeloid-pMON-pMON|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TNFRSF8 RNASET2 NBPF26 ADGRE5 ADGRE1

3.40e-051958452cb435dae2691e1250e26e59f9b8fb652a0c383e
ToppCellBronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FCGBP ENPP3 TMPRSS3 LTF WNK2

3.40e-05195845fc2a1d84b3d013e5cb9e7b9cdd740e4010897d20
ToppCellcellseq-Immune-Immune_Myeloid-pMON|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TNFRSF8 RNASET2 NBPF26 ADGRE5 ADGRE1

3.40e-05195845217908cb53016a6cb51f1bc3fc752c8df650df71
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SPHKAP PDE5A UNC13C CSMD3 PGR

3.48e-0519684522538376a95fe3afe8639a216a5497087aa94110
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area|World / Primary Cells by Cluster

ANK3 SPHKAP UNC13C KAT6B F12

3.57e-0519784579b9e7f2e8e33b3c547f716be5667156c48b0dfc
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area-33|World / Primary Cells by Cluster

ANK3 SPHKAP UNC13C KAT6B F12

3.57e-05197845d20f29088e9afd8a960d6f680075c380e550f8a7
ToppCellSevere-B_intermediate-10|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK3 MS4A1 RNASET2 ADGRE5 RYR1

3.65e-05198845dfae26c3513a82bb7cb8dadbfcea2a1f420b1bab
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Intermediate|GW23 / Sample Type, Dataset, Time_group, and Cell type.

NACC2 CDHR1 CSMD3 F12 PHF13

3.83e-05200845fe772d98c461c973dfc082e1fc50117c27ced804
ToppCellLPS_only-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ENPP3 SLC37A2 UNC79 ABCC6

6.02e-051128449801227fe5a6f5ae1b6c5a9e7fa7f35c4c52efe1
ToppCellSevere-B_intermediate-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

USF3 MS4A1 AFDN FRMD1

9.51e-0512684442a0bdbe18ef85146cac4e86b2b27d0b3b20d8a2
ToppCellLPS-IL1RA-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDHD1 LRP2 PGR SPDL1

9.81e-051278446b24630978eb0772b4cd3bf59e5bc4390be47619
ToppCellcontrol-B_cell|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

EP400P1 MS4A1 AFDN ITGB3

1.01e-0412884424abab941b4a2f89e13089d208d40ec02f0cad10
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TICRR MTFR2 ADGRE1 SPDL1

1.51e-04142844be63c48794a227ea55978524c0f5935342fc455e
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Tfr.Ctps_(Ctps)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TICRR FCGBP MUC6

1.54e-04558430b62b4f438a493a30bddb99e1eadd20c92704ee9
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TICRR FCGBP MUC6

1.54e-0455843fa556ea954ea868a4b23e410f3b27d69e04794ee
ToppCellControl-NK|World / Disease group and Cell class

ENPP1 CDHR1 CACHD1 TTLL10

1.55e-04143844fe08adc9472dfd4242497d6c614d0490713261da
ToppCellLPS-IL1RA-Endothelial-Mes-Like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDHD1 PDE5A PGR PHF13

1.63e-0414584490ca38c02325c5c637c32efdef634b54cc3cd105
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-immature_natural_killer_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PXDN ENPP1 UNC13C TTLL10

1.68e-0414684440fac8a298152ec7f7eeeed5a2d28541aea3b338
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLCD3 CFAP221 SH2D3A UNC79

1.72e-04147844f5109e0f4e8b46a977a763c9c72a2df9840e3977
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLCD3 CFAP221 SH2D3A UNC79

1.72e-04147844ad0c575bc9c5f201f2a7810452e8b3f741e65d89
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TICRR WDHD1 MTFR2 SPDL1

1.81e-041498442624ad3926efc9f0f169daae263cef16861f132b
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175|Adult / Lineage, Cell type, age group and donor

UNC13C CACHD1 LTF CSMD3

1.86e-04150844b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK3 NBPF26 SLC37A2 FRMD1

2.11e-041558445fabe24a784f0be46040ffc886eabd8d5ce78121
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

SHC2 RAPGEF3 TMPRSS3 TNFRSF14

2.11e-04155844a4f2fffa8d0de760c556c3f8f1c91804eedbfa68
ToppCell368C-Lymphocytic-NK_cells|368C / Donor, Lineage, Cell class and subclass (all cells)

IL17A ENPP1 CDHR1 TTLL10

2.22e-04157844ef5c0ace4cd500b6cc50fb7076298f3d3543b40c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAPGEF3 TNFRSF8 LRP2 PWWP3B

2.27e-04158844e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAPGEF3 TNFRSF8 LRP2 PWWP3B

2.27e-04158844d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

USF3 FCGBP MS4A1 ICE1

2.33e-041598442881b054bbeb479221ee3c38bbd9b0815b123579
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GABRE TICRR ADGRE5 TTLL10

2.44e-04161844a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSCAN29 USF3 ADGRE1 RYR1

2.44e-041618443f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GABRE TICRR ADGRE5 TTLL10

2.44e-0416184408920a716f6ec62538e361211455a30ad726d7be
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ENPP3 LTF WNK2 ADAMTSL2

2.50e-04162844fe546c2272a70bb5f08e6e097b9accdb891eda23
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZSCAN29 PXDN TET3 PHF13

2.56e-0416384463b0badaee3b2d827b1f4524510e3384d8f8fcde
ToppCellfacs-Trachea-18m-Hematologic-lymphocytic-B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MS4A1 TAF1C TNFRSF14 KMT2E

2.62e-041648444274a4f225cabf61f0fe27d8ea162b4eba612f87
ToppCellfacs-Trachea-18m-Hematologic-lymphocytic-B_cell-B_cell_of_the_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MS4A1 TAF1C TNFRSF14 KMT2E

2.62e-04164844d62143450f59097ad4b34603a6257f897a769ead
ToppCelldroplet-Fat-Scat-21m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFAP1L2 FCGBP PXDN PGR

2.68e-041658443f0c2486ea357d10dad0b703cf75cc29bdd5b5cf
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

USF3 AFDN KMT2E FOXJ3

2.74e-0416684432d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP ENPP3 LTF WNK2

2.80e-0416784431633899aae852873a4887e72c621474b0a51a33
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TNFRSF8 LRP2 CSMD3 RYR1

2.80e-041678443edb0570e583bb527165bcd8a4c25a042054043b
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

SPHKAP CFAP221 TMPRSS3 UNC79

2.80e-04167844e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ENPP1 CDHR1 CACHD1 TTLL10

2.80e-0416784494642b3dae035fedb6e8b9745f440096a4539f3c
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

LMTK2 INSYN2B UNC79 PGR

2.80e-041678449efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ENPP1 CDHR1 CACHD1 TTLL10

2.80e-0416784442b299273a6c72a625b204d55f4f3c4eebd6d185
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

LMTK2 INSYN2B UNC79 PGR

2.80e-04167844904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ENPP1 CDHR1 CACHD1 TTLL10

2.80e-04167844ecf5bc634e1e01efd783617eb81d1704e903ea21
ToppCellControl-NK|Control / Disease group and Cell class

ENPP1 CDHR1 CACHD1 TTLL10

2.87e-04168844683d389c8a1e791bfc773e63148115a21a6566db
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP ENPP3 LTF WNK2

2.93e-04169844db73dae011ff3749b3706e50ab46d03b775dd6bb
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP ENPP3 LTF WNK2

2.93e-0416984497b7047b87ce0052d8580565c9b44fd2aa6f0d5c
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP ENPP3 LTF WNK2

2.93e-041698441a684471dbda42e1470e5a889648666e14f25982
ToppCelldroplet-Spleen-nan-3m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSGA13 PDE5A LTF F12

3.00e-04170844dbd6c9c7be824a1ff1b31af791064127cafbd194
ToppCellASK428-Epithelial-Secretory|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

ZSCAN29 GABRE SH2D3A LTF

3.00e-041708449e275c4a70f9866f770fbdb0fe14a577287fe290
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

IL17A UNC13C CACHD1 WNK2

3.07e-041718443965ced4be6db14265a90673502fceee425837ca
ToppCelldroplet-Thymus-nan-21m-Myeloid-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MS4A1 ADGRE1 ABCC6 RYR1

3.07e-041718448bed33f61f7d12a1ac4fba33f730d839f5ee7bef
ToppCelldroplet-Spleen-nan-21m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCD3 NACC2 ADGRE1 RYR1

3.14e-041728443dc02709c2a6be2155576e5c34e1b0b3ae19b061
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MS4A1 SCN4A TNFRSF14 UNC13C

3.14e-041728443ffe721f62c0d20c1d765ecb15ed4e1aa88099f7
ToppCellInfluenza_Severe-CD4+_Tcm|Influenza_Severe / Disease group and Cell class

ANK3 ENPP1 PHYHIP AFDN

3.14e-0417284447865a04968ca28c6ff125159d9a23e37c8b8af1
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MS4A1 SCN4A TNFRSF14 UNC13C

3.14e-041728442bbe3f601a56577d200aa7ba7031f7c19b988cc1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TICRR AFAP1L2 FCGBP SPDL1

3.14e-04172844fe3d0d8cb5f613ac2cfff450599698f1533a354f
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TMPRSS3 LRP2 PWWP3B RYR1

3.21e-041738443d7c281a1a9f183a5a861d1a9c7b50d216535893
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FCGBP ANK3 CFAP221 DNAAF1

3.21e-04173844a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP ENPP3 LTF WNK2

3.21e-041738443aa1d28d4814798a772808ed29e1dbbdf92abd03
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TNFRSF8 TWNK ADAMTSL2 PGR

3.21e-04173844ab6d3507301038f944ad59ccd848b5e6eeb76d04
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP MS4A1 SCN4A TNFRSF14

3.21e-041738447c5e4809205ce1a0a301c15442af00a2e2b9b301
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP ENPP3 LTF WNK2

3.21e-04173844e8afef5ae68983eb8d6515b43952636a47e9d3d4
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TMPRSS3 LRP2 PWWP3B RYR1

3.21e-041738443aa90578371039f81b7c6fa873ec70f8f2bc7dfa
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 LTF CSMD3 UNC79

3.21e-0417384466f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 LTF CSMD3 UNC79

3.21e-04173844649b08a409095592cccf31883be69c754411280d
ToppCelldroplet-Lung-nan-21m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP221 PHYHIP TTLL10 DNAAF1

3.35e-041758443ed22ea41810e73c02db4f2d03745e4ce7e43bb1
ToppCelldroplet-Lung-nan-21m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP221 PHYHIP TTLL10 DNAAF1

3.35e-041758448fb1e5f6aa68274adf322401db8c7b80e8c554d7
ToppCelldroplet-Spleen-nan-21m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCD3 NACC2 ADGRE1 RYR1

3.42e-0417684411067b649fe21ac2bb328829ecadc2f64c2c10aa
ToppCelldroplet-Spleen-nan-21m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCD3 NACC2 ADGRE1 RYR1

3.42e-04176844130238f0707541c511f479619c4f7a3593ef0ebf
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCD3 MS4A1 TNFRSF8 SCN4A

3.42e-04176844741fdacb33d49b030a797a6099fdea0949a22e75
DrugAC1L19E7

ENPP1 ENPP3 SH2D3A ITGB3

9.89e-0637834CID000000509
DrugisodApdC

ENPP1 ENPP3

1.31e-052832CID000477021
Drugpinicolic acid

ENPP1 ENPP3

1.31e-052832CID005320604
Drug5-iodoindoxyl-3-phenylphosphonate

ENPP1 ENPP3

1.31e-052832CID000126064
DiseaseArterial calcification of infancy

ENPP1 ABCC6

7.26e-062802cv:C1859727
DiseaseArterial calcification of infancy

ENPP1 ABCC6

7.26e-062802C1859727
Diseasearterial calcification of infancy (is_implicated_in)

ENPP1 ABCC6

7.26e-062802DOID:0050644 (is_implicated_in)
Diseasepseudoxanthoma elasticum (implicated_via_orthology)

ENPP1 ABCC6

7.26e-062802DOID:2738 (implicated_via_orthology)
Diseasearterial calcification of infancy (implicated_via_orthology)

ENPP1 ABCC6

7.26e-062802DOID:0050644 (implicated_via_orthology)
DiseasePseudoxanthoma Elasticum

ENPP1 ABCC6

4.34e-054802C0033847
Diseasetransient cerebral ischemia (is_implicated_in)

ERCC1 F12

3.93e-0411802DOID:224 (is_implicated_in)
Diseasephenylalanine measurement

WDHD1 ABCC6 F12

4.55e-0455803EFO_0005001
Diseasepersulfide dioxygenase ETHE1, mitochondrial measurement

HRG F12

4.71e-0412802EFO_0008258
DiseaseCongenital myopathy (disorder)

SCN4A RYR1

4.71e-0412802C0270960
Diseasetransmembrane protein 87B measurement

HRG F12

5.55e-0413802EFO_0802158
DiseaseProteinuria

LRP2 UNC13C

7.45e-0415802HP_0000093
Diseaseresponse to hydrochlorothiazide, systolic blood pressure change measurement

TAF1C DNAAF1

8.50e-0416802EFO_0005202, EFO_0006944
DiseaseEndometrioma

NCOR1 ENPP1 LTF PGR

9.78e-04161804C0269102
DiseaseEndometriosis

NCOR1 ENPP1 LTF PGR

9.78e-04161804C0014175
Diseaseblood phosphate measurement

ENPP1 ENPP3 ABCC6 F12

1.30e-03174804EFO_0010972
Diseaseglomerulonephritis (biomarker_via_orthology)

MS4A1 ITGB3

1.34e-0320802DOID:2921 (biomarker_via_orthology)
Diseasepolycystic ovary syndrome (biomarker_via_orthology)

NCOR1 PGR

1.47e-0321802DOID:11612 (biomarker_via_orthology)
Diseaseleft ventricular structural measurement

PXDN KAT6B ITGB3

1.78e-0388803EFO_0008205
Diseasepartial thromboplastin time

HRG F12

1.93e-0324802EFO_0004310
DiseaseColitis

IL17A ADAM17

2.09e-0325802C0009319
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

ADGRE5 ADGRE1

2.62e-0328802DOID:1094 (implicated_via_orthology)
Diseasecortex volume change measurement, age at assessment

UNC13C WNK2

2.62e-0328802EFO_0008007, EFO_0021500

Protein segments in the cluster

PeptideGeneStartEntry
PFPEQSQQGECAIDP

nan

196

A8MWP4
STGNLCTEEQTPPPR

AFDN

1201

P55196
EKPPNENCNNNSPES

CDHR1

771

Q96JP9
EELQSSSCGNPGVPP

CSMD3

171

Q7Z407
TASNLCPDPGEPENG

CSMD3

481

Q7Z407
PGSPNGPNNTVCEDV

ADGRE5

196

P48960
QTEQQRISFPPSCPD

AFAP1L2

616

Q8N4X5
SPQEDSENPPCNNDP

CACHD1

1201

Q5VU97
SENPPCNNDPLSAGV

CACHD1

1206

Q5VU97
NCEPANPSEKNSPST

MS4A1

166

P11836
SSIPFLSPNCPNQEG

GORAB

346

Q5T7V8
PQGCVVERPPSSSQQ

KAT6B

1751

Q8WYB5
LCPSQPQSVPGSNIE

MUC6

1161

Q6W4X9
PDNQPFPQSVSESCP

HRG

491

P04196
SPQSCPEGEDSQSPL

MAGEC1

21

O60732
CPTGSEPLAGETPNQ

ERCC1

76

P07992
CPLQQSPRADNSAPG

PDE5A

81

O76074
DPENPEPTTTNECPS

KMT2E

1326

Q8IZD2
GPCPSQESLSQEENP

METTL16

446

Q86W50
PPDDSCQDQPGTNCA

ADAMTSL2

911

Q86TH1
PGAGEEQPACSQPSL

EP400P1

21

Q6ZTU2
PDSLPTQGETQPTCL

LMTK2

831

Q8IWU2
DGEERPSCSAQQPPS

GABRE

416

P78334
ESINEPQCPAGFETP

ENPP1

196

P22413
LTCEGDPTNEPPTEQ

LRP2

1011

P98164
DPTNEPPTEQCGLFS

LRP2

1016

P98164
ICSGQAPTPDQPDTS

TWNK

666

Q96RR1
TIPRNPGCPNSEDKN

IL17A

26

Q16552
PPDVNCSDQLGNTPL

OSBPL1A

166

Q9BXW6
PRPCQGQDPSDEKTQ

PGR

61

P06401
PPPPCFSEQQSNQVE

PATL2

326

C9JE40
SPERPACSQQEPTLG

FRMD1

31

Q8N878
QDNPEDPGNSPCSIR

SLC37A2

251

Q8TED4
QSEPPECSIGGNNLE

ICE1

686

Q9Y2F5
TAQQSQCPEGFDLPP

ENPP3

146

O14638
SPCTPEQQESFGGPD

FCGBP

3451

Q9Y6R7
PPPQQVSCNSGVSND

FOXJ3

441

Q9UPW0
PGLPQEDPSTSQGCA

FEM1A

251

Q9BSK4
EPNPSIPTSGECQEG

ANK3

3681

Q12955
TPPETCVGVAQPSQA

DNAAF1

696

Q8NEP3
PSQQDECSPREGQPV

ITGB3

506

P05106
PQPPQKDEGSNCSED

FOXR2

111

Q6PJQ5
CFLEPTSNAQNVPPD

RYR1

46

P21817
LPSSEPGPCSFQQLD

MIER2

421

Q8N344
CSPPQDSNELAPDGL

CFAP221

541

Q4G0U5
DLAQCQTPTQAAPPT

F12

291

P00748
ETEPSCQPSDPGASQ

SPHKAP

746

Q2M3C7
PDCDPNLENPGTSVK

SCN4A

1551

P35499
SQQSSDPDPNCVDRP

LTF

436

P02788
EGEEDQNPPCPRLNS

NBPF8

816

Q3BBV2
EGEEDQNPPCPRLNS

NBPF12

1366

Q5TAG4
EGEEDQNPPCPRLNS

NBPF26

811

B4DH59
DPQQSNPCPETGAAF

ABCC6

196

O95255
SENIEDPGEGPSNPC

PWWP3B

276

Q5H9M0
DPGEGPSNPCLDTSQ

PWWP3B

281

Q5H9M0
TTPPSQELTPDACAQ

TAF1C

791

Q15572
PSSPISGQPCGDDQN

NCOR1

156

O75376
PPQKEETQSCPNSLE

SPDL1

481

Q96EA4
NTPCLPEAAVSQPGS

TELO2

641

Q9Y4R8
CNTEFNTGQPPQDSP

PHYHIP

186

Q92561
SLACDPASQQPGPLN

NFIC

411

P08651
QEPVSGCGSPEQDPQ

SCARF1

791

Q14162
IDECSQSPQPCGPNS

ADGRE1

81

Q14246
NSSECPPPGNAEDDT

ADAM17

551

P78536
QPVCLPNSEENFPDG

TMPRSS3

321

P57727
QNCTEPGEQPSPKQE

RNASET2

211

O00584
NNPPPCSITQQDKES

TSGA13

101

Q96PP4
TLQDIPQAPSDPCSG

PHF13

156

Q86YI8
PNQDEPLPGSSCAIQ

RAPGEF3

541

O95398
EGVCQLPDQSPPRNS

TICRR

1741

Q7Z2Z1
QDDNSSPCPGLDNEP

UNC13C

716

Q8NB66
QPCALTALDQGPSPS

SHC2

361

P98077
APNAPQPCQVSSLSE

PLCD3

546

Q8N3E9
VQGTSPSQSCPEPEA

SH2D3A

241

Q9BRG2
LSETPAICPPQNTEN

WDHD1

1001

O75717
NVQLPCSSQGEPEPA

PXDN

541

Q92626
QCAPPLPSDTDQPQE

ZDBF2

1751

Q9HCK1
TQPDCNPTPENGEAP

TNFRSF8

331

P28908
PNTEGSAEPPCNDGL

USF3

826

Q68DE3
ENQQTCLPAPESPFA

TET3

736

O43151
FPPVQPGSNNICDSD

MTFR2

226

Q6P444
SPCLPNEGTNTDPLT

TRIML1

446

Q8N9V2
PPGTFSPNGTLEECQ

TNFRSF14

166

Q92956
EQASQDKPPGLPQSC

WNK2

1121

Q9Y3S1
PPNDGQEETASCPVQ

ZSCAN29

501

Q8IWY8
SSQEEGLRCQPSQPD

TTLL10

76

Q6ZVT0
QTSPPPINTRECGAE

UNC79

426

Q9P2D8
NPTESDTLEFPNCPG

INSYN2B

361

A6NMK8
EDAGSEPQSPCNQLQ

NACC2

136

Q96BF6