Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein kinase activity

AURKA ERBB4 EPHA6 MAP4K3 NTRK2 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

8.96e-076006912GO:0004672
GeneOntologyMolecularFunctionretinoic acid binding

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.51e-0628694GO:0001972
GeneOntologyMolecularFunctionprotein serine kinase activity

AURKA MAP4K3 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

4.26e-06363699GO:0106310
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

AURKA ERBB4 EPHA6 MAP4K3 NTRK2 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

5.04e-067096912GO:0016773
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.31e-0635694GO:0015020
GeneOntologyMolecularFunctionkinase activity

AURKA ERBB4 EPHA6 MAP4K3 NTRK2 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

1.07e-057646912GO:0016301
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

AURKA MAP4K3 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

2.21e-05446699GO:0004674
GeneOntologyMolecularFunctionretinoid binding

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.27e-0548694GO:0005501
GeneOntologyMolecularFunctionisoprenoid binding

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.46e-0549694GO:0019840
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

AURKA ERBB4 EPHA6 MAP4K3 NTRK2 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

7.99e-059386912GO:0016772
GeneOntologyMolecularFunctionprotein homodimerization activity

UGT1A4 UGT1A3 ERBB4 UGT1A6 UGT1A5 NTRK2 ANO1 LRP6 MIGA1 NR6A1 GRM6

1.03e-048156911GO:0042803
GeneOntologyMolecularFunctionL-ornithine transmembrane transporter activity

SLC7A1 SLC7A2

1.17e-045692GO:0000064
GeneOntologyMolecularFunctionprotein dimerization activity

UGT1A4 UGT1A3 AURKA ERBB4 HIF1A UGT1A6 UGT1A5 NTRK2 ANO1 LRP6 MIGA1 NR6A1 GRM6

2.15e-0412056913GO:0046983
GeneOntologyMolecularFunctionG protein-coupled glutamate receptor activity

GRM5 GRM6

4.17e-049692GO:0098988
GeneOntologyMolecularFunctionadenylate cyclase inhibiting G protein-coupled glutamate receptor activity

GRM5 GRM6

4.17e-049692GO:0001640
GeneOntologyMolecularFunctionL-lysine transmembrane transporter activity

SLC7A1 SLC7A2

4.17e-049692GO:0015189
GeneOntologyMolecularFunctionprotein heterodimerization activity

UGT1A4 UGT1A3 AURKA HIF1A UGT1A6 UGT1A5 MIGA1

4.42e-04398697GO:0046982
GeneOntologyMolecularFunctionmonocarboxylic acid binding

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.15e-04107694GO:0033293
GeneOntologyMolecularFunctionprotein serine/threonine/tyrosine kinase activity

AURKA AURKB DYRK2

5.74e-0447693GO:0004712
GeneOntologyMolecularFunctionhistone H3 kinase activity

AURKA AURKB

7.60e-0412692GO:0140996
GeneOntologyMolecularFunctionL-arginine transmembrane transporter activity

SLC7A1 SLC7A2

8.96e-0413692GO:0061459
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

ERBB4 EPHA6 NTRK2

1.48e-0365693GO:0004714
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

ERBB4 EPHA6 NTRK2 DYRK2

1.60e-03145694GO:0004713
GeneOntologyMolecularFunctionkinase binding

AURKA EEF2 HIF1A WDCP NTRK2 PAK1 IQSEC1 PAK2 GRM5 AURKB

1.74e-039696910GO:0019900
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.95e-03153694GO:0008194
GeneOntologyMolecularFunctionbasic amino acid transmembrane transporter activity

SLC7A1 SLC7A2

2.15e-0320692GO:0015174
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

ERBB4 EPHA6 NTRK2

3.19e-0385693GO:0019199
GeneOntologyMolecularFunctionglutamate receptor activity

GRM5 GRM6

3.91e-0327692GO:0008066
GeneOntologyMolecularFunctionhistone kinase activity

AURKA AURKB

4.20e-0328692GO:0035173
GeneOntologyMolecularFunctioncell adhesion molecule binding

EEF2 ANXA7 PAK4 PAK2 LAMA5 BCAM CDH13

4.56e-03599697GO:0050839
GeneOntologyBiologicalProcesscellular glucuronidation

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.57e-0721694GO:0052695
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.62e-0626694GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.62e-0626694GO:0006063
GeneOntologyBiologicalProcessprotein autophosphorylation

AURKA ERBB4 NTRK2 STK33 PAK1 PAK2 AURKB

1.11e-05228697GO:0046777
GeneOntologyBiologicalProcesstrans-synaptic signaling, modulating synaptic transmission

NTRK2 PAK1 GRM5

8.82e-0526693GO:0099550
GeneOntologyBiologicalProcesspallium development

SOX2 HIF1A NTRK2 LRP6 TRAPPC9 VPS13B

9.90e-05222696GO:0021543
GeneOntologyBiologicalProcesstelencephalon development

SOX2 ERBB4 HIF1A NTRK2 LRP6 TRAPPC9 VPS13B

1.21e-04332697GO:0021537
GeneOntologyBiologicalProcesscerebral cortex development

SOX2 HIF1A NTRK2 LRP6 TRAPPC9

1.34e-04147695GO:0021987
GeneOntologyBiologicalProcessL-ornithine transmembrane transport

SLC7A1 SLC7A2

1.64e-046692GO:1903352
GeneOntologyBiologicalProcessforebrain development

SOX2 ERBB4 HIF1A NTRK2 PAK1 LRP6 TRAPPC9 VPS13B

2.22e-04489698GO:0030900
GeneOntologyBiologicalProcessornithine transport

SLC7A1 SLC7A2

2.29e-047692GO:0015822
GeneOntologyBiologicalProcesslearning or memory

HIF1A NTRK2 PAK5 PAK1 ACSS2 GRM5 VPS13B

2.46e-04373697GO:0007611
GeneOntologyBiologicalProcessL-arginine import across plasma membrane

SLC7A1 SLC7A2

3.05e-048692GO:0097638
GeneOntologyBiologicalProcesstrans-synaptic signaling by lipid, modulating synaptic transmission

PAK1 GRM5

3.05e-048692GO:0099552
GeneOntologyBiologicalProcesstrans-synaptic signaling by endocannabinoid, modulating synaptic transmission

PAK1 GRM5

3.05e-048692GO:0099553
GeneOntologyCellularComponentchromosome passenger complex

AURKA AURKB

1.60e-046692GO:0032133
GeneOntologyCellularComponentglutamatergic synapse

AURKA EEF2 ERBB4 NTRK2 PAK1 IQSEC1 ANO1 PAK2 LAMA5 GRM5

3.31e-048176910GO:0098978
DomainPAK_BD

PAK5 PAK4 PAK1 PAK2

2.26e-096674IPR033923
DomainWASP_C

PAK5 PAK4 PAK1 PAK2

5.25e-097674IPR011026
DomainProtein_kinase_ATP_BS

AURKA ERBB4 EPHA6 MAP4K3 NTRK2 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

9.00e-093796712IPR017441
Domain-

PAK5 PAK4 PAK1 PAK2

7.33e-08126743.90.810.10
DomainPROTEIN_KINASE_ATP

AURKA ERBB4 EPHA6 MAP4K3 NTRK2 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

7.41e-084596712PS00107
DomainProt_kinase_dom

AURKA ERBB4 EPHA6 MAP4K3 NTRK2 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

1.47e-074896712IPR000719
DomainPROTEIN_KINASE_DOM

AURKA ERBB4 EPHA6 MAP4K3 NTRK2 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

1.61e-074936712PS50011
DomainPBD

PAK5 PAK4 PAK1 PAK2

2.66e-0716674SM00285
DomainPBD

PAK5 PAK4 PAK1 PAK2

3.47e-0717674PF00786
DomainKinase-like_dom

AURKA ERBB4 EPHA6 MAP4K3 NTRK2 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

4.43e-075426712IPR011009
DomainCRIB

PAK5 PAK4 PAK1 PAK2

7.02e-0720674PS50108
DomainUDPGT

UGT1A4 UGT1A3 UGT1A6 UGT1A5

8.64e-0721674PF00201
DomainCRIB_dom

PAK5 PAK4 PAK1 PAK2

8.64e-0721674IPR000095
DomainUDPGT

UGT1A4 UGT1A3 UGT1A6 UGT1A5

8.64e-0721674PS00375
DomainUDP_glucos_trans

UGT1A4 UGT1A3 UGT1A6 UGT1A5

8.64e-0721674IPR002213
DomainSer/Thr_kinase_AS

AURKA MAP4K3 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

4.96e-06357679IPR008271
DomainS_TKc

AURKA MAP4K3 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

5.19e-06359679SM00220
DomainPROTEIN_KINASE_ST

AURKA MAP4K3 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

5.55e-06362679PS00108
DomainPkinase

AURKA MAP4K3 STK33 PAK5 PAK4 PAK1 PAK2 AURKB DYRK2

8.38e-06381679PF00069
DomainAur

AURKA AURKB

3.79e-053672IPR030616
DomainCat_AA_permease

SLC7A1 SLC7A2

3.79e-053672IPR004755
DomainATG_C

ATG2A VPS13B

1.26e-045672PF09333
DomainCAT3

SLC7A1 SLC7A2

1.26e-045672IPR015606
DomainAA_permease_C

SLC7A1 SLC7A2

1.26e-045672PF13906
DomainCAT_C

SLC7A1 SLC7A2

1.26e-045672IPR029485
DomainAutophagy-rel_C

ATG2A VPS13B

1.26e-045672IPR015412
DomainVPS13_N

ATG2A VPS13B

3.50e-048672IPR026854
DomainChorein_N

ATG2A VPS13B

3.50e-048672PF12624
DomainGPCR_3_mtglu_rcpt

GRM5 GRM6

3.50e-048672IPR000162
DomainNCD3G

GRM5 GRM6

9.64e-0413672PF07562
DomainAA_permease_2

SLC7A1 SLC7A2

9.64e-0413672PF13520
DomainGPCR_3_9-Cys_dom

GRM5 GRM6

9.64e-0413672IPR011500
DomainAA/rel_permease1

SLC7A1 SLC7A2

9.64e-0413672IPR002293
DomainGPCR_3_CS

GRM5 GRM6

1.12e-0314672IPR017979
DomainCa/CaM-dep_Ca-dep_prot_Kinase

AURKA STK33 AURKB

1.95e-0369673IPR020636
DomainGPCR_3

GRM5 GRM6

2.55e-0321672IPR000337
Domain-

EEF2 LONP2

2.55e-03216723.30.230.10
DomainAA-permease/SLC12A_dom

SLC7A1 SLC7A2

2.80e-0322672IPR004841
DomainRibosomal_S5_D2-typ_fold_subgr

EEF2 LONP2

2.80e-0322672IPR014721
Domain7tm_3

GRM5 GRM6

2.80e-0322672PF00003
DomainG_PROTEIN_RECEP_F3_2

GRM5 GRM6

2.80e-0322672PS00980
DomainG_PROTEIN_RECEP_F3_3

GRM5 GRM6

2.80e-0322672PS00981
DomainAA_permease

SLC7A1 SLC7A2

2.80e-0322672PF00324
DomainG_PROTEIN_RECEP_F3_1

GRM5 GRM6

2.80e-0322672PS00979
DomainG_PROTEIN_RECEP_F3_4

GRM5 GRM6

2.80e-0322672PS50259
DomainGPCR_3_C

GRM5 GRM6

2.80e-0322672IPR017978
DomainTyrKc

ERBB4 EPHA6 NTRK2

3.90e-0388673SM00219
DomainTyr_kinase_cat_dom

ERBB4 EPHA6 NTRK2

3.90e-0388673IPR020635
DomainPROTEIN_KINASE_TYR

ERBB4 EPHA6 NTRK2

5.12e-0397673PS00109
DomainTyr_kinase_AS

ERBB4 EPHA6 NTRK2

5.12e-0397673IPR008266
DomainRibosomal_S5_D2-typ_fold

EEF2 LONP2

6.60e-0334672IPR020568
PathwayREACTOME_ACTIVATION_OF_RAC1

PAK5 PAK4 PAK1 PAK2

1.79e-0713584M6322
PathwayWP_NEURAL_CREST_CELL_MIGRATION_IN_CANCER

NTRK2 PAK5 PAK4 PAK1 PAK2

8.44e-0743585M39788
PathwayWP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS

MAP4K3 PAK5 PAK4 PAK1 PAK2

1.33e-0647585M39829
PathwayREACTOME_GLUCURONIDATION

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.06e-0625584M17787
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.06e-0625584M605
PathwayWP_GLUCURONIDATION

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.60e-0626584M39404
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.91e-0628584M19580
PathwaySIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES

ERBB4 PAK5 PAK4 PAK1 PAK2

7.86e-0667585M295
PathwayBIOCARTA_AGR_PATHWAY

PAK5 PAK4 PAK1 PAK2

9.66e-0633584M6220
PathwayKEGG_RENAL_CELL_CARCINOMA

HIF1A PAK5 PAK4 PAK1 PAK2

9.76e-0670585M13266
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

NTRK2 PAK5 PAK4 PAK1 PAK2 CDH13

9.93e-06121586M39823
PathwayWP_PLEURAL_MESOTHELIOMA

HIF1A MAP4K3 NTRK2 PAK5 PAK4 PAK1 PAK2 LAMA5 LRP6 CDH13

1.06e-054395810M42563
PathwaySIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES

PAK5 PAK4 PAK1 PAK2

1.23e-0535584M16801
PathwayREACTOME_RHOH_GTPASE_CYCLE

PAK5 PAK4 PAK1 PAK2

1.38e-0536584MM15603
PathwayREACTOME_RHOH_GTPASE_CYCLE

PAK5 PAK4 PAK1 PAK2

1.54e-0537584M41813
PathwayWP_NEURAL_CREST_CELL_MIGRATION_DURING_DEVELOPMENT

PAK5 PAK4 PAK1 PAK2

2.11e-0540584M39798
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.33e-0541584M7399
PathwayKEGG_ERBB_SIGNALING_PATHWAY

ERBB4 PAK5 PAK4 PAK1 PAK2

2.82e-0587585M12467
PathwayREACTOME_ATORVASTATIN_ADME

UGT1A4 UGT1A3 UGT1A5

2.90e-0515583MM15697
PathwayREACTOME_ASPIRIN_ADME

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.10e-0544584M45014
PathwaySIG_CHEMOTAXIS

PAK5 PAK4 PAK1 PAK2

3.39e-0545584M5193
PathwayWP_ERBB_SIGNALING

ERBB4 PAK5 PAK4 PAK1 PAK2

3.70e-0592585M39715
PathwayREACTOME_CDC42_GTPASE_CYCLE

PLEKHG4B DOCK11 PAK5 PAK4 PAK1 PAK2

4.05e-05155586M41808
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.58e-0551584M17726
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.03e-0552584M14171
PathwayREACTOME_HEME_DEGRADATION

UGT1A4 UGT1A3 UGT1A5

7.17e-0520583MM14721
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT1A4 UGT1A3 UGT1A6 UGT1A5

7.52e-0555584M14933
PathwayWP_MET_IN_TYPE_1_PAPILLARY_RENAL_CELL_CARCINOMA

PAK5 PAK4 PAK1 PAK2

9.92e-0559584M39750
PathwayWP_RAS_SIGNALING

RGL1 NTRK2 PAK5 PAK4 PAK1 PAK2

1.05e-04184586M39764
PathwayREACTOME_PREDNISONE_ADME

UGT1A4 UGT1A3 UGT1A5

1.10e-0423583MM16639
PathwayREACTOME_GLUCURONIDATION

UGT1A4 UGT1A3 UGT1A5

1.26e-0424583MM14599
PathwayKEGG_RETINOL_METABOLISM

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.36e-0464584M9488
PathwayWP_GLUCURONIDATION

UGT1A4 UGT1A3 UGT1A5

1.43e-0425583MM15820
PathwayKEGG_AXON_GUIDANCE

EPHA6 PAK5 PAK4 PAK1 PAK2

1.84e-04129585M5539
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.93e-0470584M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.15e-0472584M9257
PathwayBIOCARTA_AGR_PATHWAY

PAK4 PAK1 PAK2

2.74e-0431583MM1343
PathwayPID_AURORA_A_PATHWAY

AURKA PAK1 AURKB

2.74e-0431583M242
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT1A4 UGT1A3 UGT1A6 UGT1A5 CES3 ACSS2

2.78e-04220586M10320
PathwayREACTOME_METABOLISM_OF_PORPHYRINS

UGT1A4 UGT1A3 UGT1A5

3.01e-0432583MM14719
PathwayREACTOME_RAC2_GTPASE_CYCLE

PAK4 PAK1 PAK2 ANKLE2

4.45e-0487584MM15600
PathwayREACTOME_RHOV_GTPASE_CYCLE

PAK4 PAK1 PAK2

4.65e-0437583M41819
PathwayREACTOME_RHOV_GTPASE_CYCLE

PAK4 PAK1 PAK2

4.65e-0437583MM15610
PathwayREACTOME_RAC2_GTPASE_CYCLE

PAK4 PAK1 PAK2 ANKLE2

4.65e-0488584M41810
PathwayWP_PANCREATIC_ADENOCARCINOMA_PATHWAY

PAK5 PAK4 PAK1 PAK2

4.86e-0489584M39732
PathwayREACTOME_RHOU_GTPASE_CYCLE

PAK4 PAK1 PAK2

5.44e-0439583MM15607
PathwayREACTOME_RHOU_GTPASE_CYCLE

PAK4 PAK1 PAK2

5.86e-0440583M41816
PathwayREACTOME_RAC1_GTPASE_CYCLE

DOCK11 PAK5 PAK4 PAK1 PAK2

7.50e-04175585MM15599
PathwayWP_INTEGRINMEDIATED_CELL_ADHESION

CAPN7 PAK4 PAK1 PAK2

8.12e-04102584M39577
PathwayWP_INTEGRINMEDIATED_CELL_ADHESION

CAPN7 PAK4 PAK1 PAK2

8.12e-04102584MM15830
PathwayWP_ARYL_HYDROCARBON_RECEPTOR_PATHWAY_WP2873

UGT1A4 UGT1A6 CES3

8.30e-0445583M39615
PathwayREACTOME_ASPIRIN_ADME

UGT1A4 UGT1A3 UGT1A5

8.30e-0445583MM15694
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

AURKA NUP98 AURKB

8.85e-0446583M27397
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

UGT1A4 UGT1A3 UGT1A6 UGT1A5 CHST4

9.16e-04183585M39588
PathwayREACTOME_RAC1_GTPASE_CYCLE

DOCK11 PAK5 PAK4 PAK1 PAK2

9.39e-04184585M41809
PathwayWP_MICROTUBULE_CYTOSKELETON_REGULATION

NTRK2 PAK1 AURKB

1.00e-0348583M39566
PathwayKEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY

PAK5 PAK4 PAK1 PAK2

1.01e-03108584M9904
PathwayWP_FOCAL_ADHESION

PAK5 PAK4 PAK1 PAK2 LAMA5

1.01e-03187585MM15913
PathwayREACTOME_DRUG_ADME

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.04e-03109584M45012
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.04e-03109584M18788
PathwayKEGG_MEDICUS_REFERENCE_CENPE_INTERACTION_WITH_NDC80_COMPLEX

AURKA AURKB

1.07e-0312582M47887
PathwayREACTOME_CD28_DEPENDENT_VAV1_PATHWAY

PAK1 PAK2

1.07e-0312582M13618
PathwayREACTOME_CD28_DEPENDENT_VAV1_PATHWAY

PAK1 PAK2

1.07e-0312582MM14994
PathwayREACTOME_POU5F1_OCT4_SOX2_NANOG_ACTIVATE_GENES_RELATED_TO_PROLIFERATION

SOX2 NR6A1

1.26e-0313582M27209
PathwayKEGG_FOCAL_ADHESION

PAK5 PAK4 PAK1 PAK2 LAMA5

1.33e-03199585M7253
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PAK1 PAK2

1.47e-0314582MM15029
PathwayREACTOME_RHOJ_GTPASE_CYCLE

PAK4 PAK1 PAK2

1.49e-0355583M41815
PathwayWP_NEUROGENESIS_REGULATION_IN_THE_OLFACTORY_EPITHELIUM

SOX2 ERBB4 NTRK2

1.65e-0357583M48326
PathwayWP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE

GRM5 GRM6

1.69e-0315582M39442
PathwayWP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE

GRM5 GRM6

1.69e-0315582MM15845
PathwayREACTOME_RHOQ_GTPASE_CYCLE

PAK4 PAK1 PAK2

1.74e-0358583MM15602
PathwayREACTOME_RHOQ_GTPASE_CYCLE

PAK4 PAK1 PAK2

1.82e-0359583M41812
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PAK1 PAK2

1.92e-0316582M16498
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT1A4 UGT1A3 UGT1A5 CES3 ACSS2

2.03e-03219585MM14838
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

PAK1 PAK2

2.17e-0317582MM15215
PathwayREACTOME_RHO_GTPASE_CYCLE

PLEKHG4B DOCK11 PAK5 PAK4 PAK1 PAK2 ANKLE2

2.38e-03450587M27078
PathwayREACTOME_EPH_EPHRIN_SIGNALING

EPHA6 PAK1 PAK2

2.41e-0365583MM14911
PathwayREACTOME_EPHRIN_SIGNALING

PAK1 PAK2

2.44e-0318582MM15024
PathwayWP_ESTROGEN_METABOLISM_WP697

UGT1A3 UGT1A6

2.44e-0318582M39424
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

PLEKHG4B DOCK11 PAK5 PAK4 NUP98 PAK1 PAK2 ANKLE2 AURKB

2.53e-03720589M41838
PathwayWP_NRF2_PATHWAY

UGT1A4 UGT1A6 CES3 SLC5A12

2.68e-03141584M39454
PathwayREACTOME_EPHRIN_SIGNALING

PAK1 PAK2

2.72e-0319582M27310
PathwayPID_CDC42_PATHWAY

PAK4 PAK1 PAK2

2.98e-0370583M81
PathwayREACTOME_RHOG_GTPASE_CYCLE

PAK4 PAK2 ANKLE2

3.10e-0371583MM15604
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

PAK1 PAK2

3.32e-0321582M27485
PathwayREACTOME_RHO_GTPASES_ACTIVATE_PAKS

PAK1 PAK2

3.32e-0321582M27494
PathwayWP_REGULATION_OF_ACTIN_CYTOSKELETON

PAK5 PAK4 PAK1 PAK2

3.35e-03150584M39520
PathwayREACTOME_RHOG_GTPASE_CYCLE

PAK4 PAK2 ANKLE2

3.48e-0374583M41814
PathwayWP_REGULATION_OF_ACTIN_CYTOSKELETON

PAK5 PAK4 PAK1 PAK2

3.51e-03152584MM15834
PathwayWP_METAPATHWAY_BIOTRANSFORMATION

UGT1A4 UGT1A3 UGT1A5 CHST4

3.59e-03153584MM15844
PathwayWP_ESTROGEN_METABOLISM

UGT1A3 UGT1A5

3.65e-0322582MM15888
PathwayBIOCARTA_MAPK_PATHWAY

MAP4K3 PAK1 PAK2

3.76e-0376583MM1433
PathwayREACTOME_RHO_GTPASES_ACTIVATE_PAKS

PAK1 PAK2

3.98e-0323582MM15222
PathwayKEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION

AURKA AURKB

3.98e-0323582M47910
PathwayPID_MET_PATHWAY

PAK4 PAK1 PAK2

4.19e-0379583M48
PathwayBIOCARTA_MAPK_PATHWAY

MAP4K3 PAK1 PAK2

4.49e-0381583M13863
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL

ERBB4 NTRK2

4.70e-0325582M47934
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

DOCK11 PAK5 PAK4 NUP98 PAK1 PAK2 ANKLE2 AURKB

4.84e-03649588MM15690
PathwayREACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES

PAK1 PAK2

5.47e-0327582MM14809
PathwayREACTOME_VEGFR2_MEDIATED_VASCULAR_PERMEABILITY

PAK1 PAK2

5.47e-0327582M27422
Pubmed

Targeted disruption of the gene for the PAK5 kinase in mice.

PAK5 PAK4 PAK1 PAK2

2.12e-10669414517284
Pubmed

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.77e-09969422511988
Pubmed

A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.77e-0996941339448
Pubmed

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.95e-091069423642732
Pubmed

UDP-glucuronosyltransferases.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.95e-091069411465080
Pubmed

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.95e-091069423371916
Pubmed

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.95e-091069422558097
Pubmed

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.94e-091269419419973
Pubmed

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.94e-091269411434514
Pubmed

p21-Activated Kinases 1, 2 and 4 in Endometrial Cancers: Effects on Clinical Outcomes and Cell Proliferation.

PAK4 PAK1 PAK2

7.47e-09369326218748
Pubmed

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.00e-081369422085899
Pubmed

Genome-wide analysis of hepatic lipid content in extreme obesity.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.00e-081369425246029
Pubmed

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.40e-081469421646302
Pubmed

Human UDP-glucuronosyltransferases: metabolism, expression, and disease.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.40e-081469410836148
Pubmed

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.40e-08146949295054
Pubmed

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.40e-081469414672974
Pubmed

Genome-wide association meta-analysis for total serum bilirubin levels.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.54e-081669419414484
Pubmed

Pak to the future.

PAK4 PAK1 PAK2

2.99e-08469310461188
Pubmed

The potential role of the NEK6, AURKA, AURKB, and PAK1 genes in adenomatous colorectal polyps and colorectal adenocarcinoma.

AURKA PAK1 AURKB

2.99e-08469326423403
Pubmed

Genome-wide association of serum bilirubin levels in Korean population.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.31e-081769420639394
Pubmed

A genome-wide assessment of variability in human serum metabolism.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.38e-081969423281178
Pubmed

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.

PAK4 PAK1 PAK2

7.45e-08569323509247
Pubmed

Genetic determinants influencing human serum metabolome among African Americans.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.46e-072469424625756
Pubmed

Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.

UGT1A4 UGT1A3 UGT1A6

1.49e-07669319204906
Pubmed

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.

UGT1A4 UGT1A3 UGT1A6

4.16e-07869320610558
Pubmed

Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.

UGT1A4 UGT1A3 UGT1A6

4.16e-07869322579593
Pubmed

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation.

UGT1A4 UGT1A3 UGT1A6

4.16e-07869317179145
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT1A4 UGT1A3 UGT1A6

1.62e-061269320308471
Pubmed

Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis.

UGT1A4 UGT1A3 UGT1A6

1.62e-061269318161889
Pubmed

Daurinol Enhances the Efficacy of Radiotherapy in Lung Cancer via Suppression of Aurora Kinase A/B Expression.

AURKA AURKB

3.88e-06269225882311
Pubmed

Activation of PAK1/2 during the shedding of platelet microvesicles.

PAK1 PAK2

3.88e-06269220523167
Pubmed

Aurora B expression in metastatic effusions from advanced-stage ovarian serous carcinoma is predictive of intrinsic chemotherapy resistance.

AURKA AURKB

3.88e-06269223114921
Pubmed

Cloning and characterization of cDNAs encoding mouse Ugt1.6 and rabbit UGT1.6: differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

UGT1A3 UGT1A5

3.88e-0626928068691
Pubmed

Validating Aurora B as an anti-cancer drug target.

AURKA AURKB

3.88e-06269216912073
Pubmed

Differential expression of AURKA and AURKB genes in bone marrow stromal mesenchymal cells of myelodysplastic syndrome: correlation with G-banding analysis and FISH.

AURKA AURKB

3.88e-06269223092930
Pubmed

Hypoxia-inducible factor-1α induces ErbB4 signaling in the differentiating mammary gland.

ERBB4 HIF1A

3.88e-06269224966332
Pubmed

Inhibition of P21-activated kinases 1 and 4 synergistically suppresses the growth of pancreatic cancer by stimulating anti-tumour immunity.

PAK4 PAK1

3.88e-06269238797819
Pubmed

Deregulated expression of Aurora kinases is not a prognostic biomarker in papillary thyroid cancer patients.

AURKA AURKB

3.88e-06269225807528
Pubmed

An integrated genomic approach to identify predictive biomarkers of response to the aurora kinase inhibitor PF-03814735.

AURKA AURKB

3.88e-06269222222631
Pubmed

p21-activated kinases as viable therapeutic targets for the treatment of high-risk Ewing sarcoma.

PAK4 PAK1

3.88e-06269233414491
Pubmed

Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3: metabolite structure, kinetics, inducibility, and interindividual variability.

UGT1A4 UGT1A3

3.88e-06269224641623
Pubmed

Mitotic phosphorylation of SOX2 mediated by Aurora kinase A is critical for the stem-cell like cell maintenance in PA-1 cells.

SOX2 AURKA

3.88e-06269227249336
Pubmed

Mitotic kinases as regulators of cell division and its checkpoints.

AURKA AURKB

3.88e-06269211413462
Pubmed

Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases.

AURKA AURKB

3.88e-06269210523496
Pubmed

Expression of mitotic kinases phospho-aurora A and aurora B correlates with clinical and pathological parameters in bladder neoplasms.

AURKA AURKB

3.88e-06269220865660
Pubmed

The role of Aurora A in hypoxia-inducible factor 1α-promoting malignant phenotypes of hepatocelluar carcinoma.

AURKA HIF1A

3.88e-06269223966163
Pubmed

High expression of AURKA and AURKB is associated with unfavorable cytogenetic abnormalities and high white blood cell count in patients with acute myeloid leukemia.

AURKA AURKB

3.88e-06269220732714
Pubmed

Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and aurora kinases.

AURKA AURKB

3.88e-06269222463590
Pubmed

Constitutive p21-activated kinase (PAK) activation in breast cancer cells as a result of mislocalization of PAK to focal adhesions.

PAK1 PAK2

3.88e-06269215047871
Pubmed

The prognostic biomarker L-homoarginine is a substrate of the cationic amino acid transporters CAT1, CAT2A and CAT2B.

SLC7A1 SLC7A2

3.88e-06269228684763
Pubmed

The importance of cationic amino acid transporter expression in human skin.

SLC7A1 SLC7A2

3.88e-06269212787129
Pubmed

High aurora kinase expression identifies patients with muscle-invasive bladder cancer who have poor survival after neoadjuvant chemotherapy.

AURKA AURKB

3.88e-06269231597600
Pubmed

Expression of Aurora kinase A and B in normal and malignant cervical tissue: high Aurora A kinase expression in squamous cervical cancer.

AURKA AURKB

3.88e-06269219059698
Pubmed

Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties.

SLC7A1 SLC7A2

3.88e-0626929174363
Pubmed

Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target.

AURKA AURKB

3.88e-06269222940834
Pubmed

The p21-activated kinase 2 (PAK2), but not PAK1, regulates contraction-stimulated skeletal muscle glucose transport.

PAK1 PAK2

3.88e-06269232597567
Pubmed

The subcellular localization of type I p21-activated kinases is controlled by the disordered variable region and polybasic sequences.

PAK1 PAK2

3.88e-06269231391252
Pubmed

A Dual Non-ATP Analogue Inhibitor of Aurora Kinases A and B, Derived from Resorcinol with a Mixed Mode of Inhibition.

AURKA AURKB

3.88e-06269226808391
Pubmed

Aurora kinases as prognostic biomarkers in ovarian carcinoma.

AURKA AURKB

3.88e-06269219157502
Pubmed

Antiproliferative effect of Aurora kinase targeting in mesothelioma.

AURKA AURKB

3.88e-06269220371132
Pubmed

Control of cationic amino acid transport and retroviral receptor functions in a membrane protein family.

SLC7A1 SLC7A2

3.88e-0626928195186
Pubmed

Spatial Compartmentalization Specializes the Function of Aurora A and Aurora B.

AURKA AURKB

3.88e-06269225987563
Pubmed

P21-activated kinase 7 mediates cisplatin-resistance of esophageal squamous carcinoma cells with Aurora-A overexpression.

AURKA PAK5

3.88e-06269225436453
Pubmed

Identification of the binding site for the Lutheran blood group glycoprotein on laminin alpha 5 through expression of chimeric laminin chains in vivo.

LAMA5 BCAM

3.88e-06269212244066
Pubmed

Laminin alpha 5 mediates ectopic adhesion of hepatocellular carcinoma through integrins and/or Lutheran/basal cell adhesion molecule.

LAMA5 BCAM

3.88e-06269218635166
Pubmed

Gene expression profiles of the aurora family kinases.

AURKA AURKB

3.88e-06269216572587
Pubmed

Interaction with ErbB4 promotes hypoxia-inducible factor-1α signaling.

ERBB4 HIF1A

3.88e-06269222308027
Pubmed

PAK1, PAK1Δ15, and PAK2: similarities, differences and mutual interactions.

PAK1 PAK2

3.88e-06269231748572
Pubmed

Aurora kinases as targets in drug-resistant neuroblastoma cells.

AURKA AURKB

3.88e-06269225268132
Pubmed

Differential role for PAK1 and PAK4 during the invadopodia lifecycle.

PAK4 PAK1

3.88e-06269228301299
Pubmed

Alphaherpesvirus US3-mediated reorganization of the actin cytoskeleton is mediated by group A p21-activated kinases.

PAK1 PAK2

3.88e-06269219435845
Pubmed

Human cationic amino acid transporters are not affected by direct nitros(yl)ation.

SLC7A1 SLC7A2

3.88e-06269232008093
Pubmed

Mantle cell lymphoma harboring Burkitt's-like translocations presents differential expression of aurora kinase genes compared with others 8q abnormalities.

AURKA AURKB

3.88e-06269224683001
Pubmed

Targeting aurora kinases as a potential prognostic and therapeutical biomarkers in pediatric acute lymphoblastic leukaemia.

AURKA AURKB

3.88e-06269233277547
Pubmed

HIF-1 is involved in the negative regulation of AURKA expression in breast cancer cell lines under hypoxic conditions.

AURKA HIF1A

3.88e-06269223925655
Pubmed

Identification of C21orf59 and ATG2A as novel determinants of renal function-related traits in Japanese by exome-wide association studies.

ATG2A CFAP298

3.88e-06269228410202
Pubmed

Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases.

AURKA AURKB

3.88e-06269211784863
Pubmed

Identification of a low affinity, high capacity transporter of cationic amino acids in mouse liver.

SLC7A1 SLC7A2

3.88e-0626928385111
Pubmed

Association of the AURKA and AURKC gene polymorphisms with an increased risk of gastric cancer.

AURKA AURKB

3.88e-06269227270838
Pubmed

Single nucleotide polymorphisms rs911160 in AURKA and rs2289590 in AURKB mitotic checkpoint genes contribute to gastric cancer susceptibility.

AURKA AURKB

3.88e-06269228843004
Pubmed

P21-activated kinase 1 and 4 were associated with colorectal cancer metastasis and infiltration.

PAK4 PAK1

3.88e-06269225791829
Pubmed

Aurora kinase A and B as new treatment targets in aromatase inhibitor-resistant breast cancer cells.

AURKA AURKB

3.88e-06269225667100
Pubmed

Loss of Aurora Kinase Signaling Allows Lung Cancer Cells to Adopt Endoreplication and Form Polyploid Giant Cancer Cells That Resist Antimitotic Drugs.

AURKA AURKB

3.88e-06269233172929
Pubmed

Pharmacogenetic profiling of Aurora kinase B is associated with overall survival in metastatic colorectal cancer.

AURKA AURKB

3.88e-06269220368716
Pubmed

Regulation of cationic amino acid transporter (CAT) gene expression.

SLC7A1 SLC7A2

3.88e-0626928878860
Pubmed

An antibody to the lutheran glycoprotein (Lu) recognizing the LU4 blood type variant inhibits cell adhesion to laminin α5.

LAMA5 BCAM

3.88e-06269221858073
Pubmed

Expression of Aurora A (but not Aurora B) is predictive of survival in breast cancer.

AURKA AURKB

3.88e-06269218628459
Pubmed

Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells.

SLC7A1 SLC7A2

3.88e-06269215064952
Pubmed

BCAM and LAMA5 Mediate the Recognition between Tumor Cells and the Endothelium in the Metastatic Spreading of KRAS-Mutant Colorectal Cancer.

LAMA5 BCAM

3.88e-06269227143691
Pubmed

Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity.

AURKA AURKB

3.88e-06269233123754
Pubmed

Spindle assembly checkpoint gene expression in childhood adrenocortical tumors (ACT): Overexpression of Aurora kinases A and B is associated with a poor prognosis.

AURKA AURKB

3.88e-06269223788275
Pubmed

p21-activated kinase 4 regulates HIF-1α translation in cancer cells.

HIF1A PAK4

3.88e-06269228288786
Pubmed

p21-activated kinases: three more join the Pak.

PAK5 PAK1

3.88e-06269211950587
Pubmed

Midostaurin preferentially attenuates proliferation of triple-negative breast cancer cell lines through inhibition of Aurora kinase family.

AURKA AURKB

3.88e-06269226141684
Pubmed

Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases.

AURKA AURKB

3.88e-06269226443806
Pubmed

Allosteric modulation of a human protein kinase with monobodies.

AURKA AURKB

3.88e-06269231239342
Pubmed

PAK1 and PAK2 in cell metabolism regulation.

PAK1 PAK2

3.88e-06269234750857
Pubmed

New Treatment of Medullary and Papillary Human Thyroid Cancer: Biological Effects of Hyaluronic Acid Hydrogel Loaded With Quercetin Alone or in Combination to an Inhibitor of Aurora Kinase.

AURKA AURKB

3.88e-06269226660542
Pubmed

PAK5 promotes the cell stemness ability by phosphorylating SOX2 in lung squamous cell carcinomas.

SOX2 PAK5

3.88e-06269232721391
Pubmed

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells.

PAK1 PAK2

3.88e-0626929395435
InteractionZSWIM8 interactions

AURKA TSPYL6 TULP2 AURKB DYRK2

5.07e-0674685int:ZSWIM8
InteractionRAC2 interactions

AURKA SLC7A1 SLC7A2 DOCK11 PAK4 PAK1 PAK2 MIGA1 PIGU ANKLE2 VPS13B

1.46e-056746811int:RAC2
InteractionLIMK1 interactions

LONP2 PAK4 NUP98 PAK1 PAK2

1.91e-0597685int:LIMK1
InteractionETV6 interactions

SOX2 AURKA WDCP NUP98 LRP6

2.80e-05105685int:ETV6
Cytoband2q37

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.43e-07316942q37
CytobandEnsembl 112 genes in cytogenetic band chr2q37

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.85e-04226694chr2q37
Cytoband3q11.2

EPHA6 CRYBG3

7.07e-04266923q11.2
Cytoband20q11.22

ACSS2 PIGU

1.43e-033769220q11.22
CytobandEnsembl 112 genes in cytogenetic band chr3q11

EPHA6 CRYBG3

3.03e-0354692chr3q11
GeneFamilyUDP glucuronosyltransferases

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.37e-0632474363
GeneFamilyGlutamate metabotropic receptors|Protein phosphatase 1 regulatory subunits

GRM5 GRM6

1.83e-048472281
CoexpressionBUSSLINGER_ESOPHAGEAL_QUIESCENT_BASAL_CELLS

SLC7A1 SLC7A2 EEF2 NTRK2 LAMA5

1.73e-0677685M40001
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AURKA TICRR ACTL6B CRYBG3 CDH13

7.51e-061746956c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC7A2 ERBB4 NTRK2 LAMA5 BCAM

7.94e-0617669590f36f10c6ed440a0ca549f23219398853f1fbc3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 SLC7A2 ERBB4 ANO1 CDH13

9.85e-06184695e2de27cee3ea80f9b7a9a7884ceceeaa67b3214a
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

SLC7A1 SLC7A2 ERBB4 ABCA13 ACSS2

1.09e-05188695ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SOX2 AURKA ERBB4 EPHA6 AURKB

1.18e-0519169539220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCellIPF-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

SLC7A2 NTRK2 LAMA5 BCAM CDH13

1.21e-051926959b06c7336624ef21f8e5393725b56038a8028e57
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 ERBB4 DOCK11 ANO1 CDH13

1.21e-0519269567d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 SLC7A2 ERBB4 DOCK11 ANO1

1.21e-05192695bf1943715085c4124b1675888b0615c9500ec888
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SOX2 AURKA TICRR ERBB4 AURKB

1.27e-05194695c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB4 MAP4K3 NR6A1 TRAPPC9 VPS13B

1.34e-05196695ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SLC7A2 NTRK2 LAMA5 BCAM CDH13

1.34e-051966951d94cecd378a829dd8014fc086d7fca48c953a91
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SLC7A2 NTRK2 LAMA5 BCAM CDH13

1.34e-05196695aacec48285bcb7ccf1b538187071885e3602cc49
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB4 MAP4K3 NR6A1 TRAPPC9 VPS13B

1.40e-051986951996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA13 LAMA5 NR6A1 BCAM CDH13

1.40e-051986955374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB4 STK33 LRP6 NR6A1 ACSS2

1.44e-051996955f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ERBB4 NTRK2 LRP6 GRM5 CDH13

1.44e-0519969519a97e27a4758e794ce7246d295e112b47931a48
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SOX2 SLC7A2 ABCA13 LAMA5 BCAM

1.47e-0520069597f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellNeuronal-Inhibitory|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX2 SLC7A2 ERBB4 DOCK11 ANO1

1.47e-052006959ff8647e2de0b538e15929dca88ebb20ff7ab043
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

DOCK11 MAP4K3 ANO1 LRP6 DYRK2

1.47e-05200695bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB4 TMC2 EPHA6 ABCA13

7.60e-0514569496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

EPHA6 ABCA13 GRM5 CDH13

7.81e-05146694c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERBB4 TMC2 EPHA6 ABCA13

1.17e-04162694bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATG2A GRM6 TRAPPC9 AURKB

1.19e-04163694e4077e587895c85bc806be05ff5d451088e39468
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-7|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

SOX2 UGT1A6 NTRK2 PAK5

1.22e-0416469481c41e1b5535b7969bcf6fa2456f828e8e8e2ff7
ToppCellPND14-Immune-Immune_Myeloid-Dendritic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AURKA PAK1 DHX35 AURKB

1.34e-041686949b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AURKA PAK1 DHX35 AURKB

1.34e-041686944b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AURKA PAK1 DHX35 AURKB

1.34e-04168694c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLEKHG4B EPHA6 ANO1 FREM3

1.37e-041696943f738fc56bbc70dc77c9ba41025631f8264cd2b3
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PLEKHG4B PAK2 LAMA5 BCAM

1.37e-04169694665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PLEKHG4B PAK2 LAMA5 BCAM

1.37e-041696946614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AURKA TICRR ABCA13 AURKB

1.40e-04170694cf22a843ae2d9cd6693507fed2b7c6a45abea10e
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

UGT1A4 ABCA13 UGT1A5 BCAM

1.44e-041716943965ced4be6db14265a90673502fceee425837ca
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN7 PAK1 MEAK7 AURKB

1.50e-041736946c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCell5'-Adult-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC7A2 NTRK2 ANO1 BCAM

1.57e-04175694294a70786260c9a2b1ba16c88819d786698609e7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A2 NTRK2 ANO1 CDH13

1.57e-04175694316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell5'-Adult-LymphNode-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC7A2 NTRK2 ANO1 BCAM

1.57e-04175694798f33bd340261c048b7b45c842b2ccd1ea1fb60
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A2 NTRK2 ANO1 CDH13

1.57e-04175694a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 EPHA6 DOCK11 ANO1

1.57e-041756949d797888edb39fd12fd9cfc698a42b7bed19a5b5
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC7A2 ERBB4 NTRK2 BCAM

1.64e-04177694d731400997afea379f47ae8aa0f82802962b0861
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHGA6 STK33 ANO1 PIGU

1.71e-04179694e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCellControl-Developping_Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

AURKA TICRR SLC7A1 AURKB

1.71e-041796949383568f78b07b8cca72ece5d15fea209aa54ea9
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPN7 MIGA1 BCAM CDH13

1.79e-041816942c44c41b4e8a75ebdbaeb0c6cc5a03f17c44758c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 EPHA6 DOCK11 ANO1

1.86e-0418369404d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

SOX2 TICRR NTRK2 PAK5

1.90e-04184694ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 EPHA6 DOCK11 ANO1

1.90e-041846942ba98708dfd7f1b2a661578a334684094ff453ad
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

RGL1 DOCK11 NTRK2 CRYBG3

1.90e-0418469467164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell-4|TCGA-Uvea / Sample_Type by Project: Shred V9

DOCK11 MRPL13 VPS13B DYRK2

1.90e-041846949c56753e5e668be888662e4713cf4ce44e6c58fb
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-lung_neuroendocrine_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX2 ACTL6B GRM5 CDH13

1.94e-0418569430263c558ee331e0879abcf8b4c2427ff05f9fe7
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-Neuroendocrine|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX2 ACTL6B GRM5 CDH13

1.94e-041856941b000ca11970db8f347eb97ff44605d562aea70a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 EPHA6 DOCK11 ANO1

2.02e-04187694d413fb4b1531b297af5012a392b88128510c2de8
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLEKHG4B LAMA5 BCAM FREM3

2.02e-041876944ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

UGT1A3 ERBB4 UGT1A6 BCAM

2.02e-041876948407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARMS2 NTRK2 ANO1 BCAM

2.06e-041886940a5b93c131ce8514e996b0c2f39e0fc98636c122
ToppCellwk_08-11-Mesenchymal-Mesothelial-Early_mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PAK4 LAMA5 SLC5A12 BCAM

2.06e-041886946151051c027c7ff7d5d4bf5f1e11d7fe58eb22ed
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 SLC7A2 ERBB4 ANO1

2.06e-04188694433a25fe52914e07e7ba695881f9bcca2d9467ff
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 SLC7A2 ERBB4 ANO1

2.06e-041886944544552ebd67e9eb3e40d8511bb2b03a6e1178f8
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 EPHA6 DOCK11 ANO1

2.06e-041886948de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGL1 SLC5A12 BCAM DYRK2

2.11e-0418969409dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SOX2 AURKA ERBB4 EPHA6

2.11e-04189694c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 DOCK11 ANO1 CDH13

2.15e-0419069426843ec1d19ac85a50990705353b802745d33e4d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 SLC7A2 ERBB4 ANO1

2.15e-041906943b8d1e66ae68c1eee64095e75195d76d97e24026
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARMS2 TICRR CDH13 AURKB

2.15e-0419069431de1727822e9818652946dfb962daee77ffad68
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 SLC7A2 ERBB4 ANO1

2.15e-0419069456cc761e50fddfb5366391518b4d8e16589b6b42
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 SLC7A2 ERBB4 ANO1

2.15e-0419069425d4b591f75c26e404a34c42f1742d580af6598d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 SLC7A2 ERBB4 CDH13

2.15e-04190694be2b184a3559da41ba387ae0fdbeb9ae532868a5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 SLC7A2 ERBB4 ANO1

2.15e-04190694dc655e4782aab274f0c9b6e36a5ce315e3a1a4b9
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 EPHA6 DOCK11 ANO1

2.15e-04190694e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SOX2 SLC7A2 ABCA13 STK33

2.19e-041916947b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EEF2 ERBB4 NTRK2 BCAM

2.19e-04191694f631749ef1f2270133664cf5eb4cf545a8482bd3
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SOX2 SLC7A2 ABCA13 STK33

2.19e-041916949f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SOX2 SLC7A2 ABCA13 STK33

2.19e-04191694fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

SOX2 SLC7A2 ABCA13 STK33

2.19e-04191694ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellHealthy_Control-Epithelial-Epithelial-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

SOX2 SLC7A2 ABCA13 STK33

2.19e-0419169428caedb2e448e0c7f494100d714fa7cdcf150691
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SOX2 SLC7A2 ABCA13 STK33

2.19e-04191694b4e335e798c9617356b8e24412f9270c42dce656
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SOX2 SLC7A2 ABCA13 STK33

2.19e-04191694c4b223b33c020a064f576711a3d700eb60a2d737
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SOX2 SLC7A2 ABCA13 STK33

2.19e-041916945129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 ERBB4 EPHA6 ANO1

2.19e-041916947b386512284dfaa0e95358b28ee82632ee965e64
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SOX2 SLC7A2 ABCA13 STK33

2.19e-04191694df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX2 SLC7A2 NTRK2 MYORG

2.19e-04191694fd345837bfc40d85256b9a7e4fd3343bcbfe0ae5
ToppCellControl-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

NTRK2 LAMA5 BCAM CDH13

2.19e-041916942da83c493e60ad0278848957645277d76737a188
ToppCellHealthy_Control-Epithelial-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

SOX2 SLC7A2 ABCA13 STK33

2.19e-0419169415b9386b26caaa7d15f704c4a18881e1ce918a21
ToppCellControl-Epithelial|Control / Disease group,lineage and cell class (2021.01.30)

SOX2 SLC7A2 ABCA13 STK33

2.19e-04191694b78547dae8328244a47c83346447bdd787efbcae
ToppCellHealthy_Control-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

SOX2 SLC7A2 ABCA13 STK33

2.19e-04191694fdcdadbfc9ccae175abe4de8c7428ac4f6a67fde
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SOX2 SLC7A2 ABCA13 STK33

2.19e-04191694c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCellControl-Epithelial-Ciliated|Control / Disease group,lineage and cell class (2021.01.30)

SOX2 SLC7A2 ABCA13 STK33

2.19e-04191694cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

SOX2 SLC7A2 ABCA13 STK33

2.19e-041916946228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX2 SLC7A2 NTRK2 MYORG

2.24e-04192694d2161842a38146261847fc9061ba9322e0f087e0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 SLC7A2 ERBB4 ANO1

2.24e-04192694f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX2 SLC7A2 NTRK2 MYORG

2.24e-04192694261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-Pericytes|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC7A2 NTRK2 ANO1 BCAM

2.24e-041926947aadc7c5bd03274f9861dde2febda5c37f8afc9c
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX2 EEF2 LAMA5 BCAM

2.24e-041926945a3c66fc3ae22bd9ac90ca137dee0bcabcd20ab8
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 SLC7A2 ERBB4 ANO1

2.24e-04192694690b3d17c481159bc96b8bc7f6a66b51343ee858
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX2 EEF2 LAMA5 BCAM

2.24e-041926941f348e23843405abb1f1dc7d739fc5647333de16
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 EPHA6 DOCK11 ANO1

2.24e-041926940003d7ef9a8e521e70ac33c63aad843d9b6215c2
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 SLC5A12 TRAPPC9 VPS13B

2.24e-04192694e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 EPHA6 DOCK11 ANO1

2.28e-041936949f9eb241b0b82a6f12de6921c3acf6fed7cf65bb
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAP4K3 NUP98 TRAPPC9 VPS13B

2.28e-04193694779276e775cb2492e8dd36436295a536084a6415
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX2 SLC7A2 ERBB4 ANO1

2.28e-04193694294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 ABCA13 BCAM GRM5

2.28e-041936940f2167eef8203a5659c8c72e4e77646003d64797
ToppCellcontrol-Myeloid-Immature_Neutrophils_2|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TICRR ABCA13 RNF217 AURKB

2.28e-0419369433349830e9eba506470ad3661fad5e5a283d20ca
DrugAC1MRQNQ

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.06e-099684CID003522271
DrugDHPASiU

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.06e-099684CID000197602
DrugChebi:32663

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.06e-099684CID005460873
Drug3-iodophenol

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.06e-099684CID000012272
DrugAC1L4J7U

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.06e-099684CID000186631
DrugN-phenylmaleimide

UGT1A4 UGT1A3 UGT1A6 UGT1A5 BCAM

1.04e-0825685CID000013662
Drug4-nitrophenyl)imidazole

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.36e-0811684CID000123155
DrugAC1O5XMV

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.36e-0811684CID006442661
DrugN-OH-DABZ

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.54e-0812684CID000051366
Drug1-O-beta-D-glucopyranosyl-D-mannitol

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.54e-0812684CID000088735
Drug2,4,6-TCB

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.54e-0812684CID000037247
Drug7,7,7-triphenylheptanoic acid

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.54e-0812684CID000276709
Drugnonanoyl-N-methylglucamide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.54e-0812684CID000160090
Drugtritanol

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.10e-0813684CID000006457
Drug5-azido-UDP-glucuronic acid

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.10e-0813684CID003081279
Drugcotinine-N-glucuronide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.10e-0813684CID000000411
Drugpropranolol glucuronide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

7.12e-0814684CID000119515
DrugPCB-61

UGT1A4 UGT1A3 UGT1A6 UGT1A5

7.12e-0814684CID000036401
Drug2,2',3,5,5'-pentachlorobiphenyl

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.69e-0815684CID000040469
Drugcoumarin-3-carboxylic acid

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.69e-0815684CID000010752
Drugsulforaphane nitrile

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.69e-0815684CID000543743
Drugafloqualone

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.69e-0815684CID000002040
Drugnaphthyl sulphate

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.69e-0815684CID000114775
Drugquercetin-3,4'-diglucoside

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.29e-0716684CID005320835
Drug1'-hydroxyestragole

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.29e-0716684CID000040003
Drugbilirubin-phosphate

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.29e-0716684CID005497144
Drug3 beta,5 alpha,25R)- 3-hydroxyspirostan-12-one

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.68e-0717684CID000003573
Drug6-hydroxychrysene

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.68e-0717684CID000037766
DrugMS-222

UGT1A4 UGT1A3 EEF2 UGT1A6 UGT1A5

2.03e-0744685CID000011400
Drugethyl-beta-D-6-glucosiduronic acid

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.16e-0718684CID000152226
DrugBr 2

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.16e-0718684CID003060900
DrugSureCN12722713

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.16e-0718684CID005488034
Drug2,3,7-trichlorodibenzo-p-dioxin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.16e-0718684CID000036614
DrugApApG

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.16e-0718684CID003081975
DrugC1 11-32

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.16e-0718684CID000443077
DrugC11131

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.16e-0718684CID000443076
Drugalmokalant

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.73e-0719684CID003033962
Drug9-OH-risperidone

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.73e-0719684CID000475100
Drug5alpha-spirostan-3beta-ol

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.73e-0719684CID000091433
Drugisoamyl alcohol

UGT1A4 UGT1A3 G6PC3 UGT1A6 UGT1A5

3.17e-0748685CID000031260
Drugtectochrysin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.40e-0720684CID005281954
DrugAC1L1OBF

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.40e-0720684CID000032736
Drug4'-hydroxydiclofenac

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.40e-0720684CID000116545
Drugestriol-16-glucuronide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.19e-0721684CID000122281
Drugdulcin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.19e-0721684CID000009013
DrugBenzamidoxime hydrochloride

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.19e-0721684CID000069186
Druglevo-dromoran tartrate

UGT1A4 UGT1A3 UGT1A6 UGT1A5 GRM5 GRM6

4.81e-0798686CID000003918
Drugamonafide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.11e-0722684CID000050515
DrugN-methylpiperazine

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.11e-0722684CID000053167
Drugamidoxime

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.17e-0723684CID000465967
Drugestradiol-3-glucuronide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.17e-0723684CID000066651
Drugphenanthridine

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.17e-0723684CID000009189
DrugAS-3201

UGT1A4 UGT1A3 UGT1A6 UGT1A5

7.39e-0724684CID000153948
Drugnorclozapine

UGT1A4 UGT1A3 UGT1A6 UGT1A5 BCAM

7.60e-0757685CID000002820
Drug5-MOP

UGT1A4 UGT1A3 UGT1A6 UGT1A5

8.78e-0725684CID000002355
DrugAzMC

UGT1A4 UGT1A3 UGT1A6 UGT1A5

8.78e-0725684CID000064986
DrugN-acetylbenzidine

UGT1A4 UGT1A3 UGT1A6 UGT1A5

8.78e-0725684CID000018787
Drug5,6-benzoquinoline

UGT1A4 UGT1A3 UGT1A6 UGT1A5

8.78e-0725684CID000006796
Drugacetaminophen glucuronide

UGT1A4 UGT1A3 G6PC3 UGT1A6 UGT1A5

9.04e-0759685CID000083944
DrugDiMeIQx

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.21e-0627684CID000104739
Drugdiflunisal

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.21e-0627684CID000003059
Drugketoprofen

UGT1A4 UGT1A3 UGT1A6 UGT1A5 SLC5A12

1.36e-0664685CID000003825
DrugN-hydroxy-4-aminobiphenyl

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.41e-0628684CID000081261
DrugCARMINE

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.41e-0628684CID000014749
Drugerucin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.41e-0628684CID000078160
DrugH-Ni

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.41e-0628684CID000445665
Drugi 143

PAK4 PAK1 PAK2

1.41e-068683CID002777991
DrugAC1L1JAL

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.63e-0629684CID000004954
Drug7-hydroxy-4-trifluoromethylcoumarin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.63e-0629684CID005375667
Drugtrans-3'-hydroxycotinine

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.63e-0629684CID000000414
Drug7-hydroxycoumarin glucuronide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.63e-0629684CID000125641
Drugiberin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.63e-0629684CID000010455
Drugtolcapone

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.88e-0630684CID004659569
Drugparicalcitol

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.88e-0630684CID005281104
DrugAC1L9E0Q

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.88e-0630684CID000443095
Drugdihydroartemisinin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.88e-0630684CID000107770
Drug4-ethylphenol

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.15e-0631684CID000031242
DrugPCB 156

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.15e-0631684CID000038019
Drug4'-HPPH

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.15e-0631684CID000017732
Drugindole-2-carboxylic acid

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.46e-0632684CID000072899
DrugNNAL

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.46e-0632684CID000104856
DrugMuracein C

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.46e-0632684CID003086323
DrugAC1Q6OQG

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.79e-0633684CID000009686
DrugR(-)-Denopamine

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.79e-0633684CID000003818
Drug6-methylsalicylic acid

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.79e-0633684CID000011279
DrugBP-3,6-quinol

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.79e-0633684CID000119292
Drugnorbuprenorphine

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.79e-0633684CID000114976
Druggeniposide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.79e-0633684CID000107848
Drugestragole

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.15e-0634684CID000008815
DrugAC1NOWCJ

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.55e-0635684CID005120112
Drug3-[(3S,5R,10S,13R,14S,17R)-3-[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.55e-0635684CID010436171
Drugestrone-3-glucuronide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.55e-0635684CID000115255
Drugbenzyloxyresorufin

UGT1A4 UGT1A3 UGT1A6 UGT1A5 BCAM

3.65e-0678685CID000114982
Drug4-hydroxyestradiol

UGT1A4 UGT1A3 HIF1A UGT1A6 UGT1A5

3.89e-0679685CID000001743
DrugAC1L9DGV

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.99e-0636684CID000417381
Drugmuraglitazar

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.99e-0636684CID000206044
Druganisole

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.99e-0636684CID000007519
Drugglucoraphanin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.99e-0636684CID000656556
Drugbevirimat

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.99e-0636684CID000457928
Drugacotiamide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.46e-0637684CID005282338
DiseaseX-11793--oxidized bilirubin measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.79e-098684EFO_0021260
DiseaseSuccinimide measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.79e-098684EFO_0022118
DiseaseX-11530 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.79e-098684EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.79e-098684EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.79e-098684EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.79e-098684EFO_0800696
DiseaseX-10458 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.79e-098684EFO_0800692
DiseaseX-24849 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.79e-098684EFO_0800909
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.79e-098684EFO_0802740
DiseaseX-16946 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.79e-098684EFO_0800766
DiseaseX-11442 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.22e-099684EFO_0021236
DiseaseX-11441 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.22e-099684EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.22e-099684EFO_0004739
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.22e-099684EFO_0801037
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.22e-099684EFO_0802127
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.22e-099684EFO_0801036
DiseaseX-11880 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.22e-099684EFO_0800698
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.22e-099684EFO_0004570, GO_0009410
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.22e-099684EFO_0020691
DiseaseX-21448 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.36e-0910684EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.36e-0910684EFO_0802185
DiseaseX-23974 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.36e-0910684EFO_0800867
Diseasebilirubin measurement, response to tenofovir

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.36e-0910684EFO_0004570, EFO_0009279
DiseaseX-21796 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

8.41e-0911684EFO_0800825
Diseaseinsomnia, bilirubin measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

8.41e-0911684EFO_0004570, EFO_0004698
Diseasehistidine betaine (hercynine) measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

8.41e-0911684EFO_0800972
Diseasealdosterone measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

8.41e-0911684EFO_0010219
Diseasebiliverdin measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.26e-0812684EFO_0021033
Diseasep-cresol glucuronide measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.26e-0812684EFO_0800079
Diseaseretinol dehydrogenase 16 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.82e-0813684EFO_0802007
Diseasecholelithiasis

UGT1A4 UGT1A3 UGT1A6 UGT1A5 ANO1 VPS13B

5.58e-0888686EFO_0004799
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.00e-0817684EFO_0004611, EFO_0007800
Diseaseangiopoietin-related protein 1 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

7.70e-0818684EFO_0801382
Diseasetissue factor measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.50e-0721684EFO_0010623
Diseaseurate measurement, spine bone mineral density

UGT1A4 UGT1A3 UGT1A6 UGT1A5 CDH13

2.33e-0758685EFO_0004531, EFO_0007701
Diseasexanthurenate measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.86e-0729684EFO_0010551
Diseaseresponse to dolutegravir

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.76e-0730684EFO_0600017
Diseasethyroxine measurement

UGT1A4 UGT1A3 ERBB4 UGT1A6 UGT1A5

1.41e-0683685EFO_0005130
Diseasepregnenetriol sulfate measurement

UGT1A4 UGT1A6 UGT1A5

1.91e-0611683EFO_0800586
Diseaseplasma N-desmethylclozapine measurement

UGT1A4 UGT1A6 UGT1A5

1.91e-0611683EFO_0600039
Diseasepregnenetriol disulfate measurement

UGT1A4 UGT1A6 UGT1A5

3.29e-0613683EFO_0800587
Diseasegallstones

UGT1A4 UGT1A3 UGT1A6 UGT1A5 ANO1

5.19e-06108685EFO_0004210
DiseaseMalignant neoplasm of breast

AURKA RGL1 EEF2 ERBB4 HIF1A WDCP SURF1 NUP98 PAK1 MRPL13 GRM6 VPS13B

5.65e-0610746812C0006142
DiseaseX-21441 measurement

UGT1A4 UGT1A6 UGT1A5

7.78e-0617683EFO_0800814
Diseasehormone measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.33e-0584684EFO_0004730
Diseasearabinose measurement

ERBB4 CDH13

1.09e-047682EFO_0021030
Diseaseserum N-desmethylclozapine measurement

UGT1A6 UGT1A5

1.45e-048682EFO_0600043
Diseaseplasma clozapine measurement

UGT1A6 UGT1A5

1.45e-048682EFO_0600038
Diseaserenal cell carcinoma (is_marker_for)

AURKA ERBB4 HIF1A PAK1

2.22e-04128684DOID:4450 (is_marker_for)
Diseasemorbid obesity (is_marker_for)

HIF1A ACSS2

2.33e-0410682DOID:11981 (is_marker_for)
Diseasemonoclonal gammopathy

ERBB4 TMC2 CDH13

2.52e-0453683EFO_0000203
Diseasepallidum volume change measurement

TRAPPC9 CDH13

4.02e-0413682EFO_0021494
Diseasetransitional cell carcinoma (is_marker_for)

SOX2 ERBB4 PAK1

4.21e-0463683DOID:2671 (is_marker_for)
Diseasebilirubin measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5 PAK2 MEAK7

5.46e-04442686EFO_0004570
Diseasesusceptibility to childhood ear infection measurement

EPHA6 IQSEC1 ANO1 VPS13B

6.64e-04171684EFO_0007904
Diseasebreast cancer (is_marker_for)

SOX2 ANXA7 PAK1 CDH13

8.91e-04185684DOID:1612 (is_marker_for)
Diseasealcohol use disorder (implicated_via_orthology)

ERBB4 MAP4K3 ACTL6B ACSS2

1.08e-03195684DOID:1574 (implicated_via_orthology)
Diseaseage-related macular degeneration

ARMS2 GRM5 CDH13

1.15e-0389683EFO_0001365
DiseaseAdenocarcinoma of large intestine

AURKA ERBB4 PAK5

1.43e-0396683C1319315
DiseaseBreast Carcinoma

AURKA EEF2 ERBB4 HIF1A PAK1 MRPL13

1.50e-03538686C0678222
DiseaseCerebral Astrocytoma

HIF1A NTRK2

1.52e-0325682C0750935
DiseaseIntracranial Astrocytoma

HIF1A NTRK2

1.52e-0325682C0750936
Diseasecolon adenocarcinoma (is_marker_for)

EEF2 ANXA7

1.52e-0325682DOID:234 (is_marker_for)
DiseasePilocytic Astrocytoma

HIF1A NTRK2

1.52e-0325682C0334583
DiseaseAstrocytoma

HIF1A NTRK2

1.52e-0325682C0004114
DiseaseJuvenile Pilocytic Astrocytoma

HIF1A NTRK2

1.52e-0325682C0280783
DiseaseDiffuse Astrocytoma

HIF1A NTRK2

1.52e-0325682C0280785
DiseaseGrade I Astrocytoma

HIF1A NTRK2

1.52e-0325682C1704230
DiseaseSubependymal Giant Cell Astrocytoma

HIF1A NTRK2

1.52e-0325682C0205768
DiseaseMixed oligoastrocytoma

HIF1A NTRK2

1.52e-0325682C0547065
DiseaseChildhood Cerebral Astrocytoma

HIF1A NTRK2

1.52e-0325682C0338070
Diseasebrain cancer (implicated_via_orthology)

AURKA AURKB

1.64e-0326682DOID:1319 (implicated_via_orthology)
DiseaseGemistocytic astrocytoma

HIF1A NTRK2

1.64e-0326682C0334581
DiseaseProtoplasmic astrocytoma

HIF1A NTRK2

1.64e-0326682C0334580
DiseaseFibrillary Astrocytoma

HIF1A NTRK2

1.64e-0326682C0334582
Diseaseblood rubidium measurement

ABCA13 CDH13

1.64e-0326682EFO_0021529
Diseasemalaria

FREM3 CDH13 DYRK2

1.71e-03102683EFO_0001068
DiseaseAnaplastic astrocytoma

HIF1A NTRK2

1.77e-0327682C0334579
Diseaseprostate carcinoma in situ (is_marker_for)

AURKA AURKB

1.90e-0328682DOID:8634 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
LFRGDFVMDYPRPIM

UGT1A3

256

P35503
MLRLYPGPMVTEAEG

ARMS2

1

P0C7Q2
PRGELDEEGYMTPMR

ERBB4

1141

Q15303
LDVLENPDFMRLMYP

ANKLE2

371

Q86XL3
GTLDYLPPEMIEGRM

AURKA

291

O14965
YEAVPPMIEMGRIHK

CRYBG3

1561

Q68DQ2
LFQEMAIDIIPPYMI

ACTL6B

206

O94805
MGLFMVRPLATEYPP

ABCA13

4241

Q86UQ4
NMEELILALFMPPTY

ANXA7

246

P20073
DRVAIYMPMIPELVV

ACSS2

161

Q9NR19
VFYPDPMMVTRQEDL

CDH13

476

P55290
SIFPMPRVIYAMAED

SLC7A2

356

P52569
RTMYETEEMVIPGDP

ATG2A

781

Q2TAZ0
LLDYLTRMMPGSDPE

RGL1

171

Q9NZL6
IMVIEMIDGEPPYFN

PAK5

631

Q9P286
PLRMFEMLVVPEQEY

MAP4K3

721

Q8IVH8
HIGRLPMPEDYAMDE

NUP98

1786

P52948
RFPLMEVYDPDVGMN

PCDHGA6

151

Q9Y5G7
GIIVALFIMEPPDIM

GRM5

706

P41594
DILGPPMYEMEVSQR

LONP2

636

Q86WA8
MLAPYIPMDDDFQLR

HIF1A

561

Q16665
DGEDIPREMLMGIYE

IQSEC1

691

Q6DN90
MTPRVPMERELSFYG

G6PC3

186

Q9BUM1
EEPRAIVLDPMVGYM

LRP6

446

O75581
PFAGLTPEYMEMIIQ

ANO1

721

Q5XXA6
PEPGQGTEDRFVMYM

LAMA5

2771

O15230
EALPPEMVTRLYDGM

MEAK7

56

Q6P9B6
PDVAELIRTPMEMRY

PIGU

121

Q9H490
GIMAIEMIEGEPPYL

PAK1

451

Q13153
IMAIEMVEGEPPYLN

PAK2

431

Q13177
MGLPPYDPIRMEFEN

CFAP298

156

P57076
PAMEPTDGRMLLQYI

GRM6

431

O15303
IYSDPLRDLLMFPME

DOCK11

56

Q5JSL3
FMNVDLRERFAYPMP

CAPN7

226

Q9Y6W3
RVLPMYAGLPSFEQM

DHX35

311

Q9H5Z1
ILMMGRYVEPIEDVP

EEF2

451

P13639
LDVPPEMMPTVIDEY

CES3

381

Q6UWW8
RLEVPVEMNPEGYMT

BCAM

191

P50895
PEVILGARYGMPIDM

DYRK2

391

Q92630
LGIMVIEMVDGEPPY

PAK4

501

O96013
IPAGRPVMIVVEYME

EPHA6

741

Q9UF33
IPVTTPENLYLMGME

MIGA1

201

Q8NAN2
RFPDLMMCLPEIRYI

NR6A1

436

Q15406
NRDYVPMMVELLGPE

FREM3

261

P0C091
RDMISMYLPGAEVPE

SOX2

271

P48431
RPGYPIDLFMVEIME

CCT6B

181

Q92526
VVMYMLLRGEPPFLA

STK33

311

Q9BYT3
ELYMMPRTMVDPVRE

SURF1

131

Q15526
VGDPYVPLMVLMCRV

RNF217

251

Q8TC41
MSVFDAYMEPGPRRQ

CHST4

106

Q8NCG5
TLDYLPPEMIEGRMH

AURKB

236

Q96GD4
VCVEGDPLIMVFEYM

NTRK2

606

Q16620
EASFPRMEGMLFLPV

TICRR

296

Q7Z2Z1
DMEAYVLRPALPGTM

TULP2

271

O00295
FPMPRVIYAMAEDGL

SLC7A1

356

P30825
YFPEMERMDLPQGLR

PLEKHG4B

831

Q96PX9
LFRGDFVMDYPRPIM

UGT1A5

256

P35504
VIGEMPPAGLYEEIM

SCART1

951

Q4G0T1
RDIMSIYKEPPPGMF

UBE2Z

106

Q9H832
MMERLHLFPDEYIPE

MRPL13

121

Q9BYD1
MPSELEYMIVSFREP

VPS13B

2516

Q7Z7G8
MADMFDGRLEPIVFP

TSPYL6

36

Q8N831
YNPMPFELRVENMGL

TRAPPC9

606

Q96Q05
FGLVIIPEVLMGMPY

TMC2

271

Q8TDI7
LEYPRPVMPNMVFIG

UGT1A6

261

P19224
MTPYALPVIGEVRSM

WDCP

246

Q9H6R7
IISAPDQLMPYFVME

SLC5A12

311

Q1EHB4
LFRGDFVMDYPRPIM

UGT1A4

256

P22310
VSMLGYPFILPDMVG

MYORG

541

Q6NSJ0