Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainK_chnl_volt-dep_KCNQ

KCNQ5 KCNQ1

1.08e-045622IPR003937
DomainK_chnl_volt-dep_KCNQ_C

KCNQ5 KCNQ1

1.08e-045622IPR013821
DomainKCNQ_channel

KCNQ5 KCNQ1

1.08e-045622PF03520
DomainKelch_2

HCFC2 HCFC1

8.26e-0413622IPR011498
DomainKelch_2

HCFC2 HCFC1

8.26e-0413622PF07646
DomainGal_mutarotase_SF_dom

BEST4 MGAM2

1.43e-0317622IPR011013
Domain-

HCFC2 HCFC1

3.61e-03276222.130.10.80
Pubmed

Functional assembly of Kv7.1/Kv7.5 channels with emerging properties on vascular muscle physiology.

KCNQ5 KCNQ1

3.13e-06262224855057
Pubmed

Expression of pituitary tumour-derived, N-terminally truncated isoform of fibroblast growth factor receptor 4 (ptd-FGFR4) correlates with tumour invasiveness but not with G-protein alpha subunit (gsp) mutation in human GH-secreting pituitary adenomas.

FGFR4 GNAS

3.13e-06262218070145
Pubmed

Remodeling of Kv7.1 and Kv7.5 Expression in Vascular Tumors.

KCNQ5 KCNQ1

3.13e-06262232825637
Pubmed

Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype.

PHEX FGFR4

9.37e-06362221139072
Pubmed

Molecular expression and pharmacological identification of a role for K(v)7 channels in murine vascular reactivity.

KCNQ5 KCNQ1

9.37e-06362217519950
Pubmed

Dynamic recruitment of protein tyrosine phosphatase PTPD1 to EGF stimulation sites potentiates EGFR activation.

EGF PTPN21

9.37e-06362225062045
Pubmed

Rex1/Zfp42 as an epigenetic regulator for genomic imprinting.

KCNQ1 GNAS HCFC1

1.53e-052762321233130
Pubmed

Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.

TLL2 ITGAE NT5DC3

1.71e-052862318839057
Pubmed

A G protein-coupled, IP3/protein kinase C pathway controlling the synthesis of phosphaturic hormone FGF23.

PHEX GNAS

1.87e-05462231484825
Pubmed

Tandem immunoprecipitation of phosphotyrosine-mass spectrometry (TIPY-MS) indicates C19ORF19 becomes tyrosine-phosphorylated and associated with activated epidermal growth factor receptor.

EGF BCLAF1 HCFC1

2.83e-053362318271526
Pubmed

The contribution of Kv7 channels to pregnant mouse and human myometrial contractility.

KCNQ5 KCNQ1

3.12e-05562220132415
Pubmed

Novel expression and regulation of voltage-dependent potassium channels in placentas from women with preeclampsia.

KCNQ5 KCNQ1

4.67e-05662221730298
Pubmed

FGFR3 and FGFR4 do not mediate renal effects of FGF23.

PHEX FGFR4

4.67e-05662218753255
Pubmed

Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation.

PHEX FGFR4

4.67e-05662219966287
Pubmed

Host cell factors stimulate HIV-1 transcription by antagonizing substrate-binding function of Siah1 ubiquitin ligase to stabilize transcription elongation factor ELL2.

HCFC2 HCFC1

8.69e-05862232479599
Pubmed

Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.

HCFC2 HCFC1

8.69e-05862231804488
Pubmed

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.

HCFC2 HCFC1

1.12e-04962215199122
Pubmed

L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.

PHEX EGF KCNQ1 RYR3

1.27e-0414362420424473
Pubmed

Transcription is required for establishment of germline methylation marks at imprinted genes.

KCNQ1 GNAS

1.39e-041062219136628
Pubmed

Immunohistochemical study of genesis of the mouse oral vestibule.

EGF FGFR4

2.04e-041262214964469
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

JPH4 RYR3

2.04e-041262219095005
Pubmed

TRAF4 Maintains Deubiquitination of Caveolin-1 to Drive Glioblastoma Stemness and Temozolomide Resistance.

TRAF4 RPL18A

2.41e-041362235895752
Pubmed

WWP1 upregulation predicts poor prognosis and promotes tumor progression by regulating ubiquitination of NDFIP1 in intrahepatic cholangiocarcinoma.

BCLAF1 PTPN21 RPL18A

2.60e-046962335264565
Pubmed

Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice.

PHEX FGFR4

3.69e-041662224470103
Pubmed

Proteomic analysis identifies novel binding partners of BAP1.

GNAS HCFC2 HCFC1

4.02e-048062334591877
Pubmed

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.

MCM8 PRIM1

5.24e-041962222267201
Pubmed

Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.

PRIM1 CHD1L CNP

5.49e-048962323891004
Pubmed

Structural basis for activity regulation of MLL family methyltransferases.

HCFC2 HCFC1

7.06e-042262226886794
Pubmed

Identification and characterisation of imprinted genes in the mouse.

KCNQ1 GNAS

7.72e-042362215163367
Pubmed

ZFP57 dictates allelic expression switch of target imprinted genes.

KCNQ1 GNAS

9.14e-042562233500348
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

PAGE3 AATK BCLAF1 KCNQ1 FGFR4

9.22e-0442062528065597
Pubmed

Positioning of five genes (CASK, ARX, SAT, IMAGE cDNAs 248928 and 253949) from the human X chromosome short arm with respect to evolutionary breakpoints on the mouse X chromosome.

PHEX CDR1

9.89e-042662210920247
Pubmed

SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms.

PHEX KCNQ1

1.07e-032762236343245
Pubmed

Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.

HCFC2 ARHGEF17 HCFC1

1.28e-0311962323508102
Pubmed

TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer.

GNAS CNP

1.32e-033062234285210
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

SYNE3 MCM8 TLL2 SSX2IP PTPN21 SLC25A16

1.39e-0368662629987050
Pubmed

Dissection of behavior and psychiatric disorders using the mouse as a model.

KCNAB1 RYR3

1.41e-033162210767319
Pubmed

The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling.

NTN4 AATK

1.50e-033262231315048
Pubmed

Genome-wide association study of smoking behaviours among Bangladeshi adults.

PAGE3 TENM3

1.69e-033462224665060
Pubmed

Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.

KCNQ5 KCNQ1

1.69e-033462231024170
ToppCellwk_08-11-Epithelial-PNS-Proliferating_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SH3TC2 PSD2 AATK TENM3 TLL2 CNP

1.86e-07179626ab23fee9adab1e63d5b5cd9faba6b9a92beef425
ToppCellControl-Myeloid-MoAM3,_VCAN|Myeloid / Condition, Lineage and Cell class

PHEX SYNE3 CLEC4G CHAC1 RYR3

6.12e-061866250bf16ac48931b62bb3c33d63ff4279654148e293
ToppCelldroplet-Lung-nan-21m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG5 PSD2 PTPRCAP PRIM1 ITGAE

6.12e-061866258fc0487fc1b2fd403bd7c257fcabbff652f971c9
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

KCNQ5 PPP1R12A KCNAB1 NT5DC3 RYR3

6.61e-061896256b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellTCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

HSD3B7 CBLN3 SLC8B1 FGFR4 NT5DC3

7.32e-06193625c0d4da15d973cf6f8daa2b0af84b1baaf8491b83
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Malignant_Peripheral_Nerve_Sheath_Tumors-6|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SH3TC2 AATK TIGD4 CNP

2.23e-05118624ac4b90010d37f72c393fe29e6b9f16e1c7a338ff
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRCAP CNP ZNF287 BRWD1

4.60e-05142624a88bf4bcc80206b16dcc504cc19a3380d01e34a4
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG5 PTPRCAP ITGAE RPL18A

4.99e-05145624a9f5a32abcf3eb2c66bd65f2521a6dd4ce56c635
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG5 PTPRCAP ITGAE RPL18A

5.55e-051496244fda987bc7bb6d1dbd41b8f1f8c1bc59613255a8
ToppCellDividing_Macrophages-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

MCM8 ARHGEF39 PRIM1 BEST4

6.00e-05152624e39cfc346b35235546b303e7d73e4d9d7120a5fb
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG5 PSD2 PTPRCAP PRIM1

6.31e-05154624d0a1ff02a7e91f6923aa85b65094f78e357e377d
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC8B1 ARHGEF39 ITGAE RPL18A

7.50e-05161624afc719ffa53ab34c5628da47936da1f731dceab1
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_small-bowel / Manually curated celltypes from each tissue

NTN4 EHF ARHGEF17 RPL18A

7.86e-051636241a8c79903ed416f286ebe8a9922233affbc55d82
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSD3B7 JPH4 PRIM1 WDR44

7.86e-05163624bb09e6ca3406eee0593d9a312db7e05934309dd2
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

CERKL DNAAF3 BEST4 RYR3

8.05e-051646240e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCelldroplet-Lung-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRCAP ITGAE CNP RPL18A

8.24e-0516562454706631d819f401988e2c733dd6e59401a3585d
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 PTPRCAP EGF CNP

8.24e-0516562422293c6b55f44636440cd737efb786ff5de3373d
ToppCelldroplet-Lung-nan-3m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRCAP ITGAE CNP RPL18A

8.24e-0516562428e3083ab90eb02141f844b7f8a218ec9c43dbf9
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG5 PTPRCAP ITGAE RPL18A

8.24e-051656245f606959a060b1ae241217889560c6761ac73bbb
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CERKL TENM3 PRIM1 ADPRHL1

8.64e-05167624784776d1fcc098f84d3c2eca58fa56cb9428f434
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG5 PSD2 PTPRCAP PRIM1

8.64e-0516762453e32d6687a07f486141df9f4ab998af4c03a507
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG5 PTPRCAP PRIM1 ITGAE

8.84e-05168624ade02beb8d663fce4be2aefa10392ab849a4bbe7
ToppCellCOVID-19_Mild-PLT_2|World / Disease Group and Platelet Clusters

CERKL ADGRG5 PTPRCAP NT5DC3

9.04e-051696246abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCellCOVID-19-Heart-Adipocyte|Heart / Disease (COVID-19 only), tissue and cell type

KCNQ5 TENM3 FGFR4 RYR3

9.04e-05169624bd39f85b48207955f80ca120a11e15a0124117b9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNQ5 KCNAB1 GNAS ARHGEF17

9.25e-0517062499dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRCAP HCFC2 ITGAE CNP

9.25e-051706243ad9f950b87ee98f025ab9b4a8ed551e6a9b4764
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNQ5 KCNAB1 GNAS ARHGEF17

9.25e-051706243a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCNQ5 KCNAB1 GNAS ARHGEF17

9.25e-05170624cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCellCOVID-19_Mild-Neu_0|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

TENM3 TBC1D2B KCNQ1

9.33e-05636231ab77b6f098686bc168427159282bbf3538d4292
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PHEX TRAF4 PTPRCAP STRA6

9.46e-05171624a8adce007ff4c713f71f2359b40cb3575b28c98d
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG5 PTPRCAP ITGAE RPL18A

9.46e-05171624801893c318f7b1abc8d97bac86a00974f910a71c
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRCAP PPP1R12A CNP RPL18A

9.68e-05172624f320813177f246926bfd5862b4e0f9bd828cebab
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRCAP PPP1R12A CNP RPL18A

9.68e-05172624b3c12a4bb08ce931de6fe800b605f3e43adea0b5
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRG5 PTPRCAP ITGAE RPL18A

9.68e-0517262409c03cc7717373f10e51281be76d53979fcb7ccd
ToppCelldroplet-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRCAP CNP BRWD1 RPL18A

9.90e-0517362425d72fa7a84baf5660ead6da67327590f5c91860
ToppCelldroplet-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRCAP CNP BRWD1 RPL18A

9.90e-05173624886ac1b98f709ad7131df778b83712bf8ed313de
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC8B1 TLL2 STRA6

1.02e-0465623f14b28214f80ed23501ab28ff254c206f70d77b2
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AATK KCNQ5 PTPN21 CNP

1.08e-0417762459cf56c385c324f0844f20003d2b5049a2791e45
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG5 PTPRCAP ITGAE RPL18A

1.08e-04177624c840efec4eba746543eac0f48dd688518f0fb5f0
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPRCAP ARHGEF39 PPP1R12A ITGAE

1.08e-0417762444c38e572a9e9678c2dbb3e8b4748e7e28d404b7
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG5 SLC8B1 ARHGEF39 ITGAE

1.08e-041776243cb96d7d56c9ff90f1f8a6caaf49e580e2524c7d
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG5 PTPRCAP ITGAE RPL18A

1.10e-0417862461363c3365d3e191c47be1b2a35fa8afbfa64ff2
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAF4 MCM8 PRIM1 ITGAE

1.13e-041796249dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG5 PTPRCAP ITGAE RPL18A

1.13e-041796241309d41dbf286e9230fde6a7949e60c24d86766a
ToppCelldroplet-Kidney-nan-21m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRCAP CLEC4G CNP RPL18A

1.13e-0417962421736ae288ea6113e2a5604fbda338fc6b2b94a8
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRG5 PTPRCAP CNP RPL18A

1.15e-0418062489d3befbea2b4c06d118d6b339545ddcc1bcfacb
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EGF MRPL41 GNAS CNP

1.15e-0418062440f79b4455dbd1c2720dc32d9d77c70f835cecb3
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-CD45____T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG5 PSD2 PTPRCAP RPL18A

1.18e-04181624e8a68214930a6d15c47207656601b2209e283aae
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-migDC|lymph-node_spleen / Manually curated celltypes from each tissue

KIAA1210 TENM3 EHF STRA6

1.18e-0418162494680f8dbdf22d83801abc0819417751d363fb12
ToppCellfacs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R12A CLEC4G KCNAB1 ARHGEF17

1.23e-041836248d45dff06a199b1369576657f7f9dc0249c5f841
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG5 PSD2 PTPRCAP ITGAE

1.23e-04183624302bd0f1f8025f385a764f2a9adafdd7f1f67ea3
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AATK MCM8 CNP CHAC1

1.23e-041836248330c39184ce076e1f95fd3725b68af551d89db0
ToppCellfacs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R12A CLEC4G KCNAB1 ARHGEF17

1.23e-04183624421265fa15d5a028cb567bb0904e670473ef102b
ToppCellP03-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

AATK TENM3 TIGD4 CNP

1.25e-041846248880ff36c243cc60a524d74934d000aef26a70ac
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EGF EHF GNAS MGAM2

1.28e-04185624c4ca213a59ffab183a7719c2b4bc3f658a95002d
ToppCellcritical-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PHEX ADGRG5 PTPRCAP RPL18A

1.28e-041856244a5d1d0a757f1f4fdb911be96ed90b52182c25f0
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG5 PTPRCAP ITGAE RPL18A

1.28e-04185624212a8f6fb9eac0c6a89a20a9aa30d48c21abd375
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AATK TENM3 TLL2 CNP

1.31e-041866246f88b68735d0f7c9904eb8413e6007910d556185
ToppCelldroplet-Limb_Muscle-nan-24m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 PTPRCAP CNP RPL18A

1.34e-04187624890e80d0ee3cd548e4c1d0fa917c1d4080a06c13
ToppCelldroplet-Limb_Muscle-nan-24m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 PTPRCAP CNP RPL18A

1.34e-0418762467dc43f17f4b75c6a841bca5e2755fa895b390ab
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

KCNQ5 PPP1R12A KCNAB1 RYR3

1.36e-0418862434e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellwk_08-11-Epithelial-PNS-intermediate_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

AATK TENM3 TLL2 CNP

1.36e-041886243f3a744b2615bf72f6119f26087099110c0d21fc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTN4 SYNE3 TENM3 TLL2

1.39e-0418962406c44746fa4f02e6e2b3b635cdf2d8dfef3754d3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPP1R12A KCNAB1 ARHGEF17 NT5DC3

1.39e-04189624127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPP1R12A KCNAB1 ARHGEF17 NT5DC3

1.39e-041896242cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellCOVID-19_Moderate-pDC|World / disease group, cell group and cell class

PHEX ADGRG5 TRAF4 CNP

1.45e-0419162493adfbc0b22f6006d6d5ad67a99e33cbe9e1dfe9
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell-SMG_serous_(bronchial)-SMG_serous_(bronchial)_L.0.6.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EGF EHF GNAS MGAM2

1.45e-0419162413460059a0c1ed9f476cef28b8ad4c06349056c6
ToppCell5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EHF TBC1D2B FGFR4 MGAM2

1.45e-0419162454f07e4de61735051498846afb44b1798bed8144
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KCNQ5 CLEC4G GNAS ARHGEF17

1.45e-041916242ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTN4 SYNE3 TENM3 TLL2

1.45e-041916249c0ee270209b02043393416ecc9a81ddedfbb8b6
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTN4 SYNE3 TENM3 TLL2

1.51e-04193624d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTN4 SYNE3 TENM3 TLL2

1.51e-04193624010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-suprabasal_differentiating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNQ5 BCLAF1 SSX2IP MRPL41

1.51e-0419362449f4fbec91acda4727703e0e359ed780eefb8a22
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTN4 SYNE3 TENM3 TLL2

1.51e-041936248b77625bf3c87d39767fb391d1beaca4ab02342b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTN4 SYNE3 TENM3 TLL2

1.51e-041936243ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTN4 SYNE3 TENM3 TLL2

1.51e-04193624e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCellControl-Lymphoid-Plasma,_B_cells|Control / Condition, Lineage and Cell class

ADGRG5 TRAF4 PTPRCAP KCNQ5

1.54e-0419462431fff4361ebed6308b1e6b2b705ee6e0a695bd0c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTN4 SYNE3 TENM3 KCNAB1

1.54e-04194624e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NTN4 KCNQ5 GNAS ARHGEF17

1.57e-041956244a5d2f62aad5817d077177bf8b4ff0e46d3b8d97
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NTN4 KCNQ5 GNAS ARHGEF17

1.57e-041956247a32a8535c29b819dacba901d0658280a2631c94
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AATK TENM3 TLL2 CNP

1.60e-04196624e6adcfe1a00d4910e0b92848f8a80224e0d6db12
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NTN4 KCNQ5 GNAS ARHGEF17

1.60e-041966246708026bafd19c35c5c4e81911344d36a0f508cd
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Cacng4_(Non-anterior_nuclei)|Thalamus / BrainAtlas - Mouse McCarroll V32

ADGRG5 LOXHD1 ARSI

1.63e-04766234afc8d0e79870c635a89dd8e7ca91ebfe482b4ab
ToppCelldistal-Hematologic-Plasmacytoid_Dendritic-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PHEX ADGRG5 TRAF4 PTPRCAP

1.63e-041976243a5908deb5c5a2bf06019a102fb1652233cf2a2a
ToppCelldistal-1-Hematologic-Plasmacytoid_Dendritic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PHEX ADGRG5 TRAF4 PTPRCAP

1.63e-04197624166d47359df9279ea8c3946f10bd3d4b88c95857
ToppCellTracheal-NucSeq-Stromal-Schwann|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SH3TC2 AATK TENM3 CNP

1.63e-04197624c1b2a3fbd5f4aeb3555d8c372efc86f1052e7c65
ToppCelldistal-Hematologic-Plasmacytoid_Dendritic|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PHEX ADGRG5 TRAF4 PTPRCAP

1.66e-04198624bb03744d8372405c278a0781e2f513bed00cf2b3
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

PHEX AATK TENM3 RYR3

1.66e-041986240c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGFR4 GNAS RYR3 RPL18A

1.66e-04198624d5e91d1057e71b6a336eec95e44b2e7fe6b2c6ef
ToppCell18-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

PHEX ARHGEF39 FGFR4 ARSI

1.69e-041996247ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCelldistal-2-Hematologic-Plasmacytoid_Dendritic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PHEX ADGRG5 TRAF4 PTPRCAP

1.69e-0419962478796b05d28b35e7361b6271d4a3858faa39c45c
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EGF EHF GNAS MGAM2

1.73e-042006247c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Rbp4_(Rbp4)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CBLN3 FGFR4 ARSI

4.23e-04105623cec0bdfe2bbd87c7e84671c1eeafad17aec1cdb2
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Rbp4_(Rbp4)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

CBLN3 FGFR4 ARSI

4.23e-04105623c4b3f085c7e372e529d2c5d275faba403e830d48
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

CBLN3 FGFR4 ARSI

4.23e-04105623dc5f6d62945a699734a71b8ab1d4266db6fb2918
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TLL2 ADPRHL1 CNP

4.97e-041116234a22732094a9781867d501d9c05ba652c2f25048
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Acta2Rgs5.Acta2_(Mural.Acta2Rgs5.Acta2)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

PHEX PPP1R12A TIGD4

5.24e-041136237c5317bda7f13649af4837ca717dfdad74152f8f
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Acta2Rgs5.Acta2_(Mural.Acta2Rgs5.Acta2)|Cerebellum / BrainAtlas - Mouse McCarroll V32

PHEX PPP1R12A TIGD4

5.24e-041136233c745f4d975475860e793f304a846b032515b334
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

PHEX PPP1R12A TIGD4

5.24e-04113623d67022ae14fae91f9f21ebe8c6ab6d8d6d725bc4
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Intermediate|GW19 / Sample Type, Dataset, Time_group, and Cell type.

HSD3B7 BEST4 KCNQ1

6.24e-04120623eb5b88c47dd4a6f9b55ace24f19d4e81d4ed31e1
DiseaseMicrophthalmia associated with colobomatous cyst

TENM3 STRA6

1.02e-048572C2931501
Diseaselong QT syndrome (implicated_via_orthology)

KCNQ5 KCNQ1

1.63e-0410572DOID:2843 (implicated_via_orthology)
Diseaseresponse to acetylsalicylate

DNAAF3 KCNQ1

4.32e-0416572GO_1903492
Diseaseplasma beta-amyloid 1-40 measurement

DNAAF3 KCNQ1

4.89e-0417572EFO_0005659
Diseaseheart conduction disease (implicated_via_orthology)

PHEX KCNQ5

1.75e-0332572DOID:10273 (implicated_via_orthology)
Diseasepeptic ulcer disease

CERKL GNAS

1.86e-0333572MONDO_0004247
Diseasehyperuricemia

KCNQ1 GNAS

1.86e-0333572EFO_0009104

Protein segments in the cluster

PeptideGeneStartEntry
GFSGLLLRWRGSIYK

BEST4

16

Q8NFU0
YVGRADGKRGSWRTG

SSX2IP

231

Q9Y2D8
LRGRKGTYWEGGVRG

ARSI

311

Q5FYB1
YRQGLRLGGWLFRAI

HSD3B7

206

Q9H2F3
WYKEGSRLAPAGRVR

FGFR4

66

P22455
KRAVRGWSRLAGATY

ADCK5

506

Q3MIX3
LGRRGFSGRLGGYWK

CDR1

166

P51861
GRQAKGLTSGRWFLR

ARHGEF39

216

Q8N4T4
RRDFYWLRSFLAGGI

SLC25A16

31

P16260
YRSVSFKLLERWSGG

ARHGEF17

11

Q96PE2
NTRLYIWSGRDGYRK

HCFC1

331

P51610
RSKYVGLWGRLRFAR

KCNQ1

181

P51787
VAIGTRLYFWSGRDG

HCFC2

321

Q9Y5Z7
RGRGFGRGRFQSWKR

MCM8

6

Q9UJA3
WSLGFQLSRRDYGGI

MGAM2

331

Q2M2H8
LYWGGKAETERGLSR

KCNAB1

171

Q14722
DRRGGTWKLLGSVVY

KCNQ5

246

Q9NR82
EGLGVERKSRWTYRG

JPH4

71

Q96JJ6
IWLDYPRGKRGFSRG

LOXHD1

1456

Q8IVV2
WSGGALLYDTRSRRG

ITGAE

426

P38570
EGGREKSFRYWPRLG

PTPN21

1001

Q16825
YLWELTRSKTGGERG

PAGE3

71

Q5JUK9
GFKHRLWVYSGRRGV

PRIM1

151

P49642
LSYRGERVAARGYWG

DNAAF3

261

Q8N9W5
GRRFYWTDRGKSLIG

EGF

566

P01133
GRRLVYKFGKNARGW

EHF

281

Q9NZC4
VDYWAKRGRGRGTFQ

BCLAF1

856

Q9NYF8
DSRVGFVRGYSRRFW

CHAC1

51

Q9BUX1
WGRGGLFTALEKRSA

CHD1L

746

Q86WJ1
REKTYRKWSSEGRGG

ADPRHL1

256

Q8NDY3
GFGGRTLALAEKYRW

CERKL

351

Q49MI3
ELSRGKLYSLGNGRW

CNP

366

P09543
WNGRRLRTYGKAPFS

BRWD1

2096

Q9NSI6
AAYGRRWRRKGASVS

KIAA1210

531

Q9ULL0
LRLRRGNLLGGWKYS

CBLN3

181

Q6UW01
FRGRVTLAWALGYLG

SLC8B1

221

Q6J4K2
RGAKGIGFLTSGWRF

MRPL41

36

Q8IXM3
GFQKTRRWRGLGSLF

SYNE3

906

Q6ZMZ3
GRHSLLYLKEIGRGW

AATK

121

Q6ZMQ8
RGKRTLYPESWTDRG

NTN4

561

Q9HB63
YGRHDWRLKGSLSRG

NDUFV1

46

P49821
YEFLKLTGWRGSRVL

NT5DC3

371

Q86UY8
ALAWRRLSRDSGGYY

PTPRCAP

51

Q14761
WRGKSESSRGRRVYY

GNAS

551

Q5JWF2
LSRKRDWTGSYQIGR

SH3TC2

256

Q8TF17
KNFGIWLRYDSRSGT

RPL18A

76

Q02543
GASRGRARWGLAYTL

STRA6

631

Q9BX79
IRRYVFKLGVLGWGA

ADGRG5

351

Q8IZF4
FLTRNTRGRGYWLGL

CLEC4G

211

Q6UXB4
DYDDRLERRGKGGFW

ZNF287

271

Q9HBT7
LGGTRLFRWLYEKFR

TMEM68

246

Q96MH6
RTPRGRRGWKKFYAV

PSD2

531

Q9BQI7
YEAGGAGTRARSLWR

RYR3

251

Q15413
TLSRDYKWNGFGRSL

ZNF514

146

Q96K75
YKWNGFGRSLGLRSV

ZNF514

151

Q96K75
GWLDRFKSRYGLVFR

TIGD4

131

Q8IY51
RYFLSGSLDGKLRLW

WDR44

661

Q5JSH3
VRDGYWRKAPLLGRF

TLL2

411

Q9Y6L7
DNGGLREAFRAYRKW

PHEX

646

P78562
SGWTVIYRYDGLGRR

TENM3

2221

Q9P273
SDGVLIWKIGSYGRR

TRAF4

306

Q9BUZ4
GKGPLRGYRSRWFVF

TBC1D2B

46

Q9UPU7
WRLGLRKTGSYGALA

PPP1R12A

436

O14974