Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	1-alkylglycerophosphocholine O-acetyltransferase activity	LPCAT1 LPCAT4 LPCAT2	1.72e-07	3	112	3	GO:0047192
GeneOntologyMolecularFunction	peptidase activity	MBTPS1 PSEN2 ACR RNPEPL1 CAPN1 MMP23B CASP9 ERVK-7 TINAGL1 MINDY3 ADAMTS6 AOPEP ADAMTS16 USP15 CTSZ	3.78e-06	654	112	15	GO:0008233
GeneOntologyMolecularFunction	1-acylglycerol-3-phosphate O-acyltransferase activity	LPCAT1 AGPAT5 LPCAT4 LPCAT2	5.21e-06	21	112	4	GO:0003841
GeneOntologyMolecularFunction	lysophosphatidic acid acyltransferase activity	LPCAT1 AGPAT5 LPCAT4 LPCAT2	9.14e-06	24	112	4	GO:0042171
GeneOntologyMolecularFunction	lysophospholipid acyltransferase activity	LPCAT1 AGPAT5 LPCAT4 LPCAT2	9.14e-06	24	112	4	GO:0071617
GeneOntologyMolecularFunction	1-acylglycerophosphocholine O-acyltransferase activity	LPCAT1 LPCAT4 LPCAT2	9.42e-06	8	112	3	GO:0047184
GeneOntologyMolecularFunction	O-acetyltransferase activity	LPCAT1 LPCAT4 LPCAT2	1.41e-05	9	112	3	GO:0016413
GeneOntologyMolecularFunction	2-acylglycerol-3-phosphate O-acyltransferase activity	LPCAT1 LPCAT4 LPCAT2	1.41e-05	9	112	3	GO:0047144
GeneOntologyMolecularFunction	acylglycerol O-acyltransferase activity	LPCAT1 AGPAT5 LPCAT4 LPCAT2	2.99e-05	32	112	4	GO:0016411
GeneOntologyMolecularFunction	endopeptidase activity	MBTPS1 PSEN2 ACR CAPN1 MMP23B CASP9 ERVK-7 ADAMTS6 ADAMTS16 USP15 CTSZ	3.03e-05	430	112	11	GO:0004175
GeneOntologyMolecularFunction	plasmalogen synthase activity	LPCAT1 LPCAT2	3.12e-05	2	112	2	GO:0047159
GeneOntologyMolecularFunction	O-acyltransferase activity	LPCAT1 AGPAT5 LPCAT4 LPCAT2	3.37e-04	59	112	4	GO:0008374
GeneOntologyMolecularFunction	cysteine-type peptidase activity	CAPN1 CASP9 TINAGL1 MINDY3 USP15 CTSZ	7.52e-04	192	112	6	GO:0008234
GeneOntologyMolecularFunction	choline transmembrane transporter activity	SLC5A7 SLC44A1	8.54e-04	8	112	2	GO:0015220
GeneOntologyMolecularFunction	metallopeptidase activity	MBTPS1 RNPEPL1 MMP23B ADAMTS6 AOPEP ADAMTS16	9.30e-04	200	112	6	GO:0008237
GeneOntologyMolecularFunction	gap junction channel activity involved in cell communication by electrical coupling	GJB6 GJB2	1.09e-03	9	112	2	GO:1903763
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH1 DNAH5 HTT	1.16e-03	37	112	3	GO:0045505
GeneOntologyMolecularFunction	cysteine-type endopeptidase activity	CAPN1 CASP9 USP15 CTSZ	1.40e-03	86	112	4	GO:0004197
GeneOntologyBiologicalProcess	glycerolipid biosynthetic process	LPCAT1 AGPAT5 PIGS LPCAT4 SREBF1 PTDSS2 SLC44A1 LPCAT2 CLN3 PLD2	1.74e-06	268	110	10	GO:0045017
GeneOntologyBiologicalProcess	glycerophospholipid biosynthetic process	LPCAT1 AGPAT5 PIGS LPCAT4 PTDSS2 SLC44A1 LPCAT2 CLN3 PLD2	2.48e-06	217	110	9	GO:0046474
GeneOntologyBiologicalProcess	glycerophospholipid metabolic process	LPCAT1 AGPAT5 PIGS LPCAT4 PTDSS2 SLC44A1 LPCAT2 CLN3 PLA2G4F PLD2	8.36e-06	320	110	10	GO:0006650
GeneOntologyBiologicalProcess	phosphatidylglycerol acyl-chain remodeling	LPCAT1 LPCAT4 PLA2G4F	1.21e-05	9	110	3	GO:0036148
GeneOntologyBiologicalProcess	phospholipid biosynthetic process	LPCAT1 AGPAT5 PIGS LPCAT4 PTDSS2 SLC44A1 LPCAT2 CLN3 PLD2	1.37e-05	268	110	9	GO:0008654
GeneOntologyBiologicalProcess	glycerolipid metabolic process	LPCAT1 AGPAT5 PIGS LPCAT4 SREBF1 PTDSS2 SLC44A1 LPCAT2 CLN3 PLA2G4F PLD2	1.86e-05	429	110	11	GO:0046486
GeneOntologyBiologicalProcess	lipid biosynthetic process	B3GALT1 MBTPS1 LPCAT1 AGPAT5 PIGS LPCAT4 SREBF1 PTDSS2 SLC44A1 LPCAT2 CLN3 UGCG PLA2G4F PLD2 LARGE1	2.72e-05	813	110	15	GO:0008610
GeneOntologyBiologicalProcess	phosphatidic acid biosynthetic process	LPCAT1 AGPAT5 LPCAT4 PLD2	3.95e-05	36	110	4	GO:0006654
GeneOntologyBiologicalProcess	phosphatidylcholine acyl-chain remodeling	LPCAT1 LPCAT4 LPCAT2	5.15e-05	14	110	3	GO:0036151
GeneOntologyBiologicalProcess	phosphatidic acid metabolic process	LPCAT1 AGPAT5 LPCAT4 PLD2	6.66e-05	41	110	4	GO:0046473
GeneOntologyBiologicalProcess	phospholipid metabolic process	LPCAT1 AGPAT5 PIGS LPCAT4 PTDSS2 SLC44A1 LPCAT2 CLN3 PLA2G4F PLD2	6.91e-05	410	110	10	GO:0006644
GeneOntologyCellularComponent	caspase complex	PIGS CAPN1 CASP9	1.52e-05	10	107	3	GO:0008303
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	MBTPS1 LPCAT1 DPY19L3 AGPAT5 PSEN2 VPS13C PIGS MMP23B LPCAT4 SREBF1 ABCB6 PTDSS2 LPCAT2 CLN3 VPS13A NAV3 PLD2 GABBR1	1.31e-04	1327	107	18	GO:0042175
GeneOntologyCellularComponent	secretory vesicle	LPCAT1 PSEN2 VPS13C ACR CAPN1 SLC5A7 ITGA2B PTPRB ABCC8 CLN3 VPS13A LRP1 RACGAP1 TMEM95 DNASE1 CTSZ GABBR1	1.92e-04	1246	107	17	GO:0099503
GeneOntologyCellularComponent	endoplasmic reticulum membrane	MBTPS1 LPCAT1 DPY19L3 AGPAT5 PSEN2 VPS13C PIGS MMP23B LPCAT4 SREBF1 ABCB6 PTDSS2 LPCAT2 CLN3 VPS13A PLD2 GABBR1	2.97e-04	1293	107	17	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	MBTPS1 LPCAT1 DPY19L3 AGPAT5 PSEN2 VPS13C PIGS MMP23B LPCAT4 SREBF1 ABCB6 PTDSS2 LPCAT2 CLN3 VPS13A PLD2 GABBR1	3.13e-04	1299	107	17	GO:0098827
GeneOntologyCellularComponent	Golgi membrane	B3GALT1 MBTPS1 LPCAT1 PSEN2 SREBF1 RER1 ABCB6 LPCAT2 CLN3 CHST4 UGCG LARGE1	3.21e-04	721	107	12	GO:0000139
GeneOntologyCellularComponent	organelle outer membrane	AGPAT5 VPS13C ABCB6 ARMCX3 SLC44A1 VPS13A NAV3	5.86e-04	279	107	7	GO:0031968
GeneOntologyCellularComponent	outer membrane	AGPAT5 VPS13C ABCB6 ARMCX3 SLC44A1 VPS13A NAV3	6.11e-04	281	107	7	GO:0019867
HumanPheno	Hyperkeratotic papule	COL7A1 GJB6 GJB2 LRP1	3.59e-06	13	45	4	HP:0045059
HumanPheno	Posterior blepharitis	GJB6 SREBF1 GJB2	2.20e-05	7	45	3	HP:0025610
Domain	Acyltransferase	LPCAT1 AGPAT5 LPCAT4 LPCAT2	1.96e-06	16	110	4	PF01553
Domain	PlsC	LPCAT1 AGPAT5 LPCAT4 LPCAT2	2.56e-06	17	110	4	SM00563
Domain	Plipid/glycerol_acylTrfase	LPCAT1 AGPAT5 LPCAT4 LPCAT2	2.56e-06	17	110	4	IPR002123
Domain	VPS13	VPS13C VPS13A	1.03e-04	3	110	2	IPR026847
Domain	VPS13_mid_rpt	VPS13C VPS13A	1.03e-04	3	110	2	PF16910
Domain	VPS13	VPS13C VPS13A	1.03e-04	3	110	2	PF16908
Domain	VPS13_N2	VPS13C VPS13A	1.03e-04	3	110	2	IPR031646
Domain	VPS13_mid_rpt	VPS13C VPS13A	1.03e-04	3	110	2	IPR031642
Domain	SHR-BD	VPS13C VPS13A	2.05e-04	4	110	2	IPR009543
Domain	Peptidase_M1_C	RNPEPL1 AOPEP	2.05e-04	4	110	2	IPR015211
Domain	Leuk-A4-hydro_C	RNPEPL1 AOPEP	2.05e-04	4	110	2	SM01263
Domain	VPS13_C	VPS13C VPS13A	2.05e-04	4	110	2	PF16909
Domain	Leuk-A4-hydro_C	RNPEPL1 AOPEP	2.05e-04	4	110	2	PF09127
Domain	VPS13_C	VPS13C VPS13A	2.05e-04	4	110	2	IPR031645
Domain	SHR-BD	VPS13C VPS13A	2.05e-04	4	110	2	PF06650
Domain	ZINC_PROTEASE	RNPEPL1 MMP23B ADAMTS6 AOPEP ADAMTS16	2.84e-04	98	110	5	PS00142
Domain	Autophagy-rel_C	VPS13C VPS13A	3.40e-04	5	110	2	IPR015412
Domain	ATG_C	VPS13C VPS13A	3.40e-04	5	110	2	PF09333
Domain	THIOL_PROTEASE_HIS	CAPN1 TINAGL1 CTSZ	5.25e-04	27	110	3	PS00639
Domain	Pept_cys_AS	CAPN1 TINAGL1 CTSZ	5.85e-04	28	110	3	IPR000169
Domain	Chorein_N	VPS13C VPS13A	9.40e-04	8	110	2	PF12624
Domain	VPS13_N	VPS13C VPS13A	9.40e-04	8	110	2	IPR026854
Domain	-	TENM1 LRP1 LRP5	1.56e-03	39	110	3	2.120.10.30
Domain	ARM-rpt_dom	GPRASP1 ARMCX3	1.83e-03	11	110	2	IPR006911
Domain	Arm_2	GPRASP1 ARMCX3	1.83e-03	11	110	2	PF04826
Domain	Peptidase_M1	RNPEPL1 AOPEP	2.18e-03	12	110	2	IPR001930
Domain	6-blade_b-propeller_TolB-like	TENM1 LRP1 LRP5	2.51e-03	46	110	3	IPR011042
Domain	Peptidase_M1_N	RNPEPL1 AOPEP	2.57e-03	13	110	2	IPR014782
Domain	Pept_C1	TINAGL1 CTSZ	2.57e-03	13	110	2	SM00645
Domain	Peptidase_C1A_C	TINAGL1 CTSZ	2.57e-03	13	110	2	IPR000668
Domain	Peptidase_C1	TINAGL1 CTSZ	2.57e-03	13	110	2	PF00112
Domain	Peptidase_M1	RNPEPL1 AOPEP	2.57e-03	13	110	2	PF01433
Domain	Peptidase_C1A	TINAGL1 CTSZ	2.57e-03	13	110	2	IPR013128
Domain	Dynein_heavy_chain_D4_dom	DNAH1 DNAH5	2.99e-03	14	110	2	IPR024317
Domain	Dynein_HC_stalk	DNAH1 DNAH5	2.99e-03	14	110	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH1 DNAH5	2.99e-03	14	110	2	IPR013602
Domain	DHC_N2	DNAH1 DNAH5	2.99e-03	14	110	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH1 DNAH5	2.99e-03	14	110	2	IPR011704
Domain	PLAC	ADAMTS6 ADAMTS16	2.99e-03	14	110	2	PF08686
Domain	MT	DNAH1 DNAH5	2.99e-03	14	110	2	PF12777
Domain	AAA_8	DNAH1 DNAH5	2.99e-03	14	110	2	PF12780
Domain	Ldl_recept_b	LRP1 LRP5	2.99e-03	14	110	2	PF00058
Domain	LDLRB	LRP1 LRP5	2.99e-03	14	110	2	PS51120
Domain	AAA_5	DNAH1 DNAH5	2.99e-03	14	110	2	PF07728
Domain	DHC_fam	DNAH1 DNAH5	3.43e-03	15	110	2	IPR026983
Domain	Beta/gamma_crystallin	CRYBB1 CRYBB2	3.43e-03	15	110	2	IPR001064
Domain	Dynein_heavy	DNAH1 DNAH5	3.43e-03	15	110	2	PF03028
Domain	LY	LRP1 LRP5	3.43e-03	15	110	2	SM00135
Domain	CRYSTALLIN_BETA_GAMMA	CRYBB1 CRYBB2	3.43e-03	15	110	2	PS50915
Domain	Dynein_heavy_dom	DNAH1 DNAH5	3.43e-03	15	110	2	IPR004273
Domain	Crystall	CRYBB1 CRYBB2	3.43e-03	15	110	2	PF00030
Domain	XTALbg	CRYBB1 CRYBB2	3.43e-03	15	110	2	SM00247
Domain	LDLR_classB_rpt	LRP1 LRP5	3.43e-03	15	110	2	IPR000033
Domain	ARM-type_fold	GPRASP1 RNPEPL1 TRIP12 ARMCX3 AOPEP TAF6 HTT	3.94e-03	339	110	7	IPR016024
Domain	G_crystallin-rel	CRYBB1 CRYBB2	4.95e-03	18	110	2	IPR011024
Domain	CONNEXINS_1	GJB6 GJB2	5.51e-03	19	110	2	PS00407
Domain	PLAC	ADAMTS6 ADAMTS16	5.51e-03	19	110	2	PS50900
Domain	PLAC	ADAMTS6 ADAMTS16	5.51e-03	19	110	2	IPR010909
Pathway	REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS	LPCAT1 AGPAT5 LPCAT4 PTDSS2 SLC44A1 LPCAT2 PLA2G4F PLD2	3.43e-07	120	79	8	MM14585
Pathway	REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS	LPCAT1 AGPAT5 LPCAT4 PTDSS2 SLC44A1 LPCAT2 PLA2G4F PLD2	5.64e-07	128	79	8	M706
Pathway	REACTOME_PHOSPHOLIPID_METABOLISM	LPCAT1 AGPAT5 LPCAT4 PTDSS2 SLC44A1 LPCAT2 PLEKHA5 PLA2G4F PLD2	1.44e-06	196	79	9	MM14591
Pathway	REACTOME_PHOSPHOLIPID_METABOLISM	LPCAT1 AGPAT5 LPCAT4 PTDSS2 SLC44A1 LPCAT2 PLEKHA5 PLA2G4F PLD2	2.64e-06	211	79	9	M649
Pathway	REACTOME_ACYL_CHAIN_REMODELLING_OF_PC	LPCAT1 LPCAT4 LPCAT2 PLA2G4F	1.45e-05	27	79	4	M643
Pathway	REACTOME_ACYL_CHAIN_REMODELLING_OF_PC	LPCAT1 LPCAT4 LPCAT2 PLA2G4F	1.69e-05	28	79	4	MM14575
Pathway	KEGG_ETHER_LIPID_METABOLISM	LPCAT1 LPCAT4 LPCAT2 PLD2	3.30e-05	33	79	4	M2130
Pathway	REACTOME_SYNTHESIS_OF_PA	LPCAT1 AGPAT5 LPCAT4 PLD2	6.47e-05	39	79	4	M653
Pathway	KEGG_GLYCEROPHOSPHOLIPID_METABOLISM	LPCAT1 LPCAT4 PTDSS2 LPCAT2 PLD2	7.01e-05	77	79	5	M9131
Pathway	REACTOME_SYNTHESIS_OF_PA	LPCAT1 AGPAT5 LPCAT4 PLD2	7.90e-05	41	79	4	MM14583
Pathway	REACTOME_ACYL_CHAIN_REMODELLING_OF_PG	LPCAT1 LPCAT4 PLA2G4F	1.30e-04	18	79	3	M700
Pathway	REACTOME_ACYL_CHAIN_REMODELLING_OF_PG	LPCAT1 LPCAT4 PLA2G4F	1.54e-04	19	79	3	MM14581
Pathway	REACTOME_METABOLISM_OF_LIPIDS	MBTPS1 LPCAT1 AGPAT5 LPCAT4 SREBF1 PTDSS2 SLC44A1 LPCAT2 UGCG PLEKHA5 PLA2G4F PLD2	1.62e-04	620	79	12	MM15193
Pathway	BIOCARTA_S1P_PATHWAY	MBTPS1 SREBF1	4.58e-04	6	79	2	MM1556
Pathway	REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF	MBTPS1 SREBF1	6.39e-04	7	79	2	MM14639
Pathway	WP_ALZHEIMERS_DISEASE	PSEN2 CAPN1 CASP9 LRP1	7.81e-04	74	79	4	MM15962
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	COL7A1 MBTPS1 NPR1 DPY19L3 PIGS HTATIP2 LPCAT4 SREBF1 RER1 PTDSS2 BTN2A1 BMPR2 LPCAT2 RRAGA LRP1 LRP5 PLEKHA5 USP15 CTSZ HTT	2.20e-09	1201	114	20	35696571
Pubmed	Mammalian acyl-CoA:lysophosphatidylcholine acyltransferase enzymes.	LPCAT1 LPCAT4 LPCAT2	3.43e-08	3	114	3	18156367
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DIP2B MBTPS1 VPS13C CAPN1 DNAH1 PCNX2 TMCO4 BMPR2 PTPRB AOPEP RALGPS1 ABCC8 SMARCA2 LRP1 LRP5 KYAT3 USP15 TMEM181 HTT	3.75e-07	1489	114	19	28611215
Pubmed	HIV-1 Tat interaction with cyclin T1 represses mannose receptor and the bone morphogenetic protein receptor-2 transcription.	MRC1 HTATIP2 BMPR2	6.81e-07	6	114	3	16615932
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MBTPS1 UNC5A ZBED4 SLIT1 NAV3 TCF25 USP15 TMEM181 LARGE1	8.28e-06	407	114	9	12693553
Pubmed	The interaction between C5a and sphingosine-1-phosphate in neutrophils for antineutrophil cytoplasmic antibody mediated activation.	MBTPS1 C5	1.07e-05	2	114	2	25000985
Pubmed	Prevalence of DFNB1 mutations among cochlear implant users in Slovakia and its clinical implications.	GJB6 GJB2	1.07e-05	2	114	2	23700267
Pubmed	A novel DFNB1 deletion allele supports the existence of a distant cis-regulatory region that controls GJB2 and GJB6 expression.	GJB6 GJB2	1.07e-05	2	114	2	20236118
Pubmed	Prevalence of DFNB1 mutations in Argentinean children with non-syndromic deafness. Report of a novel mutation in GJB2.	GJB6 GJB2	1.07e-05	2	114	2	20022641
Pubmed	GJB2 and GJB6 genes: molecular study and identification of novel GJB2 mutations in the hearing-impaired Argentinean population.	GJB6 GJB2	1.07e-05	2	114	2	19887791
Pubmed	Mutation R184Q of connexin 26 in hearing loss patients has a dominant-negative effect on connexin 26 and connexin 30.	GJB6 GJB2	1.07e-05	2	114	2	20442751
Pubmed	Common mutation analysis of GJB2 and GJB6 genes in affected families with autosomal recessive non-syndromic hearing loss from Iran: simultaneous detection of two common mutations (35delG/del(GJB6-D13S1830)) in the DFNB1-related deafness.	GJB6 GJB2	1.07e-05	2	114	2	17368814
Pubmed	Connexin Type and Fluorescent Protein Fusion Tag Determine Structural Stability of Gap Junction Plaques.	GJB6 GJB2	1.07e-05	2	114	2	26265468
Pubmed	GJB2 and GJB6 mutations are an infrequent cause of autosomal-recessive nonsyndromic hearing loss in residents of Mexico.	GJB6 GJB2	1.07e-05	2	114	2	25288386
Pubmed	GJB2 (connexin 26) variants and nonsyndromic sensorineural hearing loss: a HuGE review.	GJB6 GJB2	1.07e-05	2	114	2	12172392
Pubmed	Prevalence of DFNB1 mutations in Slovak patients with non-syndromic hearing loss.	GJB6 GJB2	1.07e-05	2	114	2	22281373
Pubmed	Particular distribution of the GJB2/GJB6 gene mutations in Mexican population with hearing impairment.	GJB6 GJB2	1.07e-05	2	114	2	24774219
Pubmed	GJB2 mutation spectrum in 209 hearing impaired individuals of predominantly Caribbean Hispanic and African descent.	GJB6 GJB2	1.07e-05	2	114	2	20381175
Pubmed	The spectrum of GJB2 gene mutations in Algerian families with nonsyndromic hearing loss from Sahara and Kabylie regions.	GJB6 GJB2	1.07e-05	2	114	2	31200317
Pubmed	Phenotypic variability of non-syndromic hearing loss in patients heterozygous for both c.35delG of GJB2 and the 342-kb deletion involving GJB6.	GJB6 GJB2	1.07e-05	2	114	2	14759569
Pubmed	Mutation analysis of GJB2 and GJB6 genes in Southeastern Brazilians with hereditary nonsyndromic deafness.	GJB6 GJB2	1.07e-05	2	114	2	20563649
Pubmed	Double heterozygosity with mutations involving both the GJB2 and GJB6 genes is a possible, but very rare, cause of congenital deafness in the Czech population.	GJB6 GJB2	1.07e-05	2	114	2	15638823
Pubmed	Decreased expression of connexin-30 and aberrant expression of connexin-26 in human head and neck cancer.	GJB6 GJB2	1.07e-05	2	114	2	17695503
Pubmed	Performance of speech perception after cochlear implantation in DFNB1 patients.	GJB6 GJB2	1.07e-05	2	114	2	19051073
Pubmed	A deletion mutation in GJB6 cooperating with a GJB2 mutation in trans in non-syndromic deafness: A novel founder mutation in Ashkenazi Jews.	GJB6 GJB2	1.07e-05	2	114	2	11668644
Pubmed	Detection of the 35delG/GJB2 and del(GJB6-D13S1830) mutations in Venezuelan patients with autosomal recessive nonsyndromic hearing loss.	GJB6 GJB2	1.07e-05	2	114	2	18294049
Pubmed	Hearing loss features in GJB2 biallelic mutations and GJB2/GJB6 digenic inheritance in a large Italian cohort.	GJB6 GJB2	1.07e-05	2	114	2	19173109
Pubmed	Prevalence of GJB2 mutations and the del(GJB6-D13S1830) in Argentinean non-syndromic deaf patients.	GJB6 GJB2	1.07e-05	2	114	2	15964725
Pubmed	Screening for the GJB2 c.-3170 G>A (IVS 1+1 G>A) mutation in Brazilian deaf individuals using multiplex ligation-dependent probe amplification.	GJB6 GJB2	1.07e-05	2	114	2	19715470
Pubmed	Connexins 26 and 30 are co-assembled to form gap junctions in the cochlea of mice.	GJB6 GJB2	1.07e-05	2	114	2	12859965
Pubmed	GJB2 and GJB6 mutations in 165 Danish patients showing non-syndromic hearing impairment.	GJB6 GJB2	1.07e-05	2	114	2	15345117
Pubmed	Permeation pathway of homomeric connexin 26 and connexin 30 channels investigated by molecular dynamics.	GJB6 GJB2	1.07e-05	2	114	2	22292956
Pubmed	GJB2 and GJB6 screening in Tunisian patients with autosomal recessive deafness.	GJB6 GJB2	1.07e-05	2	114	2	23434199
Pubmed	Low incidence of GJB2, GJB6 and mitochondrial DNA mutations in North Indian patients with non-syndromic hearing impairment.	GJB6 GJB2	1.07e-05	2	114	2	19465004
Pubmed	Screening for monogenetic del(GJB6-D13S1830) and digenic del(GJB6-D13S1830)/GJB2 patterns of inheritance in deaf individuals from Eastern Austria.	GJB6 GJB2	1.07e-05	2	114	2	15464308
Pubmed	Prevalence of the GJB2 mutations and the del(GJB6-D13S1830) mutation in Brazilian patients with deafness.	GJB6 GJB2	1.07e-05	2	114	2	15464305
Pubmed	Analysis of the presence of the GJB6 mutations in patients heterozygous for GJB2 mutation in Brazil.	GJB6 GJB2	1.07e-05	2	114	2	23553242
Pubmed	Connexin-Mediated Signaling in Nonsensory Cells Is Crucial for the Development of Sensory Inner Hair Cells in the Mouse Cochlea.	GJB6 GJB2	1.07e-05	2	114	2	28077706
Pubmed	Restoration of connexin26 protein level in the cochlea completely rescues hearing in a mouse model of human connexin30-linked deafness.	GJB6 GJB2	1.07e-05	2	114	2	17227867
Pubmed	A large deletion including most of GJB6 in recessive non syndromic deafness: a digenic effect?	GJB6 GJB2	1.07e-05	2	114	2	11896458
Pubmed	Connexin 26 and 30 mutations in paediatric patients with congenital, non-syndromic hearing loss treated with cochlear implantation in Mediterranean Turkey.	GJB6 GJB2	1.07e-05	2	114	2	23171692
Pubmed	Analysis of the GJB2 and GJB6 genes in Italian patients with nonsyndromic hearing loss: frequencies, novel mutations, genotypes, and degree of hearing loss.	GJB6 GJB2	1.07e-05	2	114	2	19371219
Pubmed	Nonsyndromic Hearing Loss and Deafness, DFNA3 – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	GJB6 GJB2	1.07e-05	2	114	2	20301708
Pubmed	Mice with conditional deletion of Cx26 exhibit no vestibular phenotype despite secondary loss of Cx30 in the vestibular end organs.	GJB6 GJB2	1.07e-05	2	114	2	26232528
Pubmed	Coordinated control of connexin 26 and connexin 30 at the regulatory and functional level in the inner ear.	GJB6 GJB2	1.07e-05	2	114	2	19047647
Pubmed	Polyglutamine-modulated striatal calpain activity in YAC transgenic huntington disease mouse model: impact on NMDA receptor function and toxicity.	CAPN1 HTT	1.07e-05	2	114	2	19036965
Pubmed	Characterization of TH1 and CTSZ, two non-imprinted genes downstream of GNAS1 in chromosome 20q13.	NELFCD CTSZ	1.07e-05	2	114	2	11030415
Pubmed	Single nucleotide polymorphisms of the GJB2 and GJB6 genes are associated with autosomal recessive nonsyndromic hearing loss.	GJB6 GJB2	1.07e-05	2	114	2	26075227
Pubmed	Clinical comparison of hearing-impaired patients with DFNB1 against heterozygote carriers of connexin 26 mutations.	GJB6 GJB2	1.07e-05	2	114	2	21287563
Pubmed	Ethnicity and mutations in GJB2 (connexin 26) and GJB6 (connexin 30) in a multi-cultural Canadian paediatric Cochlear Implant Program.	GJB6 GJB2	1.07e-05	2	114	2	16125251
Pubmed	Single nucleotide polymorphisms and haplotypes analysis of DFNB1 locus in Chinese sporadic hearing impairment population.	GJB6 GJB2	1.07e-05	2	114	2	19719946
Pubmed	DFNB1-associated deafness in Portuguese cochlear implant users: prevalence and impact on oral outcome.	GJB6 GJB2	1.07e-05	2	114	2	20650534
Pubmed	Super-resolution structured illumination fluorescence microscopy of the lateral wall of the cochlea: the Connexin26/30 proteins are separately expressed in man.	GJB6 GJB2	1.07e-05	2	114	2	26941236
Pubmed	Analysis of connexin subunits required for the survival of vestibular hair cells.	GJB6 GJB2	1.07e-05	2	114	2	17702002
Pubmed	Frequency of Usher syndrome in two pediatric populations: Implications for genetic screening of deaf and hard of hearing children.	GJB6 GJB2	1.07e-05	2	114	2	20613545
Pubmed	Expression of gap junction proteins connexins 26, 30, and 43 in Dupuytren's disease.	GJB6 GJB2	1.07e-05	2	114	2	24359029
Pubmed	Mutation screen of beta-crystallin genes in 274 patients with age-related macular degeneration.	CRYBB1 CRYBB2	1.07e-05	2	114	2	20565250
Pubmed	Permeability and gating properties of human connexins 26 and 30 expressed in HeLa cells.	GJB6 GJB2	1.07e-05	2	114	2	12767933
Pubmed	Molecular interactions between presenilin and calpain: inhibition of m-calpain protease activity by presenilin-1, 2 and cleavage of presenilin-1 by m-, mu-calpain.	PSEN2 CAPN1	1.07e-05	2	114	2	10677567
Pubmed	Identification of a novel noninflammatory biosynthetic pathway of platelet-activating factor.	LPCAT1 LPCAT2	1.07e-05	2	114	2	18285344
Pubmed	Frequency of GJB2 mutations, GJB6-D13S1830 and GJB6-D13S1854 deletions among patients with non-syndromic hearing loss from the central region of Iran.	GJB6 GJB2	1.07e-05	2	114	2	31162818
Pubmed	First report of prevalence c.IVS1+1G>A and del (GJB6-13S1854) mutations in Syrian families with non-syndromic sensorineural hearing loss.	GJB6 GJB2	1.07e-05	2	114	2	28012540
Pubmed	The digenic hypothesis unraveled: the GJB6 del(GJB6-D13S1830) mutation causes allele-specific loss of GJB2 expression in cis.	GJB6 GJB2	1.07e-05	2	114	2	19723508
Pubmed	A study of GJB2 and delGJB6-D13S1830 mutations in Brazilian non-syndromic deaf children from the Amazon region.	GJB6 GJB2	1.07e-05	2	114	2	23503914
Pubmed	[New recurrent extended deletion, including GJB2 and GJB6 genes, results in isolated sensorineural hearing impairment with autosomal recessive type of inheritance].	GJB6 GJB2	1.07e-05	2	114	2	25715449
Pubmed	Connexin 26 variants and auditory neuropathy/dys-synchrony among children in schools for the deaf.	GJB6 GJB2	1.07e-05	2	114	2	16222667
Pubmed	NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population.	NELFCD CTSZ	1.07e-05	2	114	2	29795304
Pubmed	Connexin26 gap junction mediates miRNA intercellular genetic communication in the cochlea and is required for inner ear development.	GJB6 GJB2	1.07e-05	2	114	2	26490746
Pubmed	Hearing impairment in Dutch patients with connexin 26 (GJB2) and connexin 30 (GJB6) mutations.	GJB6 GJB2	1.07e-05	2	114	2	15656949
Pubmed	The association between GJB2 mutation and GJB6 gene in non syndromic hearing loss school children.	GJB6 GJB2	1.07e-05	2	114	2	22106692
Pubmed	GJB2 and GJB6 Genetic Variant Curation in an Argentinean Non-Syndromic Hearing-Impaired Cohort.	GJB6 GJB2	1.07e-05	2	114	2	33096615
Pubmed	Melanoma progression exhibits a significant impact on connexin expression patterns in the epidermal tumor microenvironment.	GJB6 GJB2	1.07e-05	2	114	2	19844737
Pubmed	Infant hearing loss and connexin testing in a diverse population.	GJB6 GJB2	1.07e-05	2	114	2	18580690
Pubmed	Phenotype/genotype correlations in a DFNB1 cohort with ethnical diversity.	GJB6 GJB2	1.07e-05	2	114	2	18758381
Pubmed	GJB2 and GJB6 gene mutations found in Indian probands with congenital hearing impairment.	GJB6 GJB2	1.07e-05	2	114	2	20086291
Pubmed	Non-syndromic hearing impairment in a multi-ethnic population of Northeastern Brazil.	GJB6 GJB2	1.07e-05	2	114	2	23684175
Pubmed	Brain-specific transcript variants of 5' and 3' ends of mouse VPS13A and VPS13C.	VPS13C VPS13A	1.07e-05	2	114	2	17196930
Pubmed	Pediatric cholesteatoma and variants in the gene encoding connexin 26.	GJB6 GJB2	1.07e-05	2	114	2	19877196
Pubmed	Frequency and distribution of GJB2 (connexin 26) and GJB6 (connexin 30) mutations in a large North American repository of deaf probands.	GJB6 GJB2	1.07e-05	2	114	2	12865758
Pubmed	Genotyping for Cx26 and Cx30 mutations in cases with congenital hearing loss.	GJB6 GJB2	1.07e-05	2	114	2	18554165
Pubmed	Connexin gene mutations among Ugandan patients with nonsyndromic sensorineural hearing loss.	GJB6 GJB2	1.07e-05	2	114	2	24706568
Pubmed	Conserved intramolecular disulfide bond is critical to trafficking and fate of ATP-binding cassette (ABC) transporters ABCB6 and sulfonylurea receptor 1 (SUR1)/ABCC8.	ABCB6 ABCC8	1.07e-05	2	114	2	21199866
Pubmed	Connexin 26 and 30 genes mutations in patients with chronic rhinosinusitis.	GJB6 GJB2	1.07e-05	2	114	2	17989577
Pubmed	Novel connexin 30 and connexin 26 mutational spectrum in patients with progressive sensorineural hearing loss.	GJB6 GJB2	1.07e-05	2	114	2	22704424
Pubmed	In vivo genetic manipulation of inner ear connexin expression by bovine adeno-associated viral vectors.	GJB6 GJB2	1.07e-05	2	114	2	28779115
Pubmed	Connexin 26 and connexin 30 mutations in children with nonsyndromic hearing loss.	GJB6 GJB2	1.07e-05	2	114	2	15064611
Pubmed	The presenilin 2 loop domain interacts with the mu-calpain C-terminal region.	PSEN2 CAPN1	1.07e-05	2	114	2	9852298
Pubmed	Clouston syndrome with heterozygous GJB6 mutation p.Ala88Val and GJB2 variant p.Val27Ile revealing mild sensorineural hearing loss and photophobia.	GJB6 GJB2	1.07e-05	2	114	2	23863883
Pubmed	Etiology of unilateral hearing loss in a national hereditary deafness repository.	GJB6 GJB2	1.07e-05	2	114	2	22534022
Pubmed	Human connexin26 and connexin30 form functional heteromeric and heterotypic channels.	GJB6 GJB2	1.07e-05	2	114	2	17615163
Pubmed	Screening for GJB2 and GJB6 gene mutations in patients from Campania region with sensorineural hearing loss.	GJB6 GJB2	1.07e-05	2	114	2	20233142
Pubmed	Gap junction-mediated intercellular biochemical coupling in cochlear supporting cells is required for normal cochlear functions.	GJB6 GJB2	1.07e-05	2	114	2	16217030
Pubmed	A multicenter study of the frequency and distribution of GJB2 and GJB6 mutations in a large North American cohort.	GJB6 GJB2	1.07e-05	2	114	2	17666888
Pubmed	Expression of GJB2 and GJB6 is reduced in a novel DFNB1 allele.	GJB6 GJB2	1.07e-05	2	114	2	16773579
Pubmed	Prevalence of 35delG/GJB2 and del (GJB6-D13S1830) mutations in patients with non-syndromic deafness from a population of Espírito Santo-Brazil.	GJB6 GJB2	1.07e-05	2	114	2	20835527
Pubmed	Novel beta-crystallin gene mutations in Chinese families with nuclear cataracts.	CRYBB1 CRYBB2	1.07e-05	2	114	2	21402992
Pubmed	GJB2 mutations: Genotypic and phenotypic correlation in a cohort of 690 hearing-impaired patients, toward a new mutation?	GJB6 GJB2	1.07e-05	2	114	2	29106882
Pubmed	GJB2 and GJB6 mutations in children with congenital cytomegalovirus infection.	GJB6 GJB2	1.07e-05	2	114	2	17426645
Pubmed	Role of GJB2 and GJB6 in Iranian Nonsyndromic Hearing Impairment: From Molecular Analysis to Literature Reviews.	GJB6 GJB2	1.07e-05	2	114	2	31215297
Pubmed	GJB2 and GJB6 genes and the A1555G mitochondrial mutation are only minor causes of nonsyndromic hearing loss in the Qatari population.	GJB6 GJB2	1.07e-05	2	114	2	22103400
Interaction	RAMP3 interactions	LPCAT1 AGPAT5 LPCAT4 ABCB6 PTDSS2 BTN2A1 LPCAT2 PLD2	5.93e-06	176	111	8	int:RAMP3
Cytoband	22q13.33	ACR ZBED4 MOV10L1	1.18e-04	38	114	3	22q13.33
Cytoband	9q21	IARS1 VPS13A	3.31e-04	11	114	2	9q21
GeneFamily	1-acylglycerol-3-phosphate O-acyltransferases	LPCAT1 AGPAT5 LPCAT4 LPCAT2	7.06e-08	11	71	4	46
GeneFamily	Low density lipoprotein receptors	LRP1 LRP5	1.15e-03	13	71	2	634
GeneFamily	Beta-gamma crystallins	CRYBB1 CRYBB2	1.54e-03	15	71	2	1359
GeneFamily	Dyneins, axonemal	DNAH1 DNAH5	1.99e-03	17	71	2	536
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS6 ADAMTS16	2.49e-03	19	71	2	50
GeneFamily	Gap junction proteins	GJB6 GJB2	3.34e-03	22	71	2	314
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAML1 DNAH1 SORCS1 ADAMTS16 TENM1 NAV3 DNAH5	4.57e-07	184	113	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAML1 DNAH1 SORCS1 ADAMTS16 TENM1 NAV3 DNAH5	4.57e-07	184	113	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAML1 DNAH1 SORCS1 ADAMTS16 TENM1 NAV3 DNAH5	4.57e-07	184	113	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GPRASP1 MMP23B SORCS1 KLHDC1 TENM1 KYAT3	2.72e-06	154	113	6	ec920cae12ea1d14b6c973f6e903f895f80e3c50
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RFX3 SLIT1 CCDC28A-AS1 CFAP57 TMC5 DNAH5	4.66e-06	169	113	6	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-lymphatic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MRC1 NPR1 UNC5A UBTD1 PTPRB NAV3	8.06e-06	186	113	6	86b218a400f9c64f92b050f00b49f09647b17437
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-lymphatic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MRC1 NPR1 ITGA2B UNC5A UBTD1 PTPRB	8.06e-06	186	113	6	5d94e6dd2c92e0c46badeb1e6eb54b69af855a66
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MRC1 NPR1 UNC5A UBTD1 PTPRB NAV3	8.06e-06	186	113	6	f51c76b1c3c6c49e0ebc9a913d8413e0b6a04d80
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MRC1 NPR1 ITGA2B UNC5A UBTD1 PTPRB	8.06e-06	186	113	6	1da52e13096dfe4eb08bd0e7461cb3809b3b3deb
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYO1E TINAGL1 BMPR2 PTPRB UGCG NAV3	9.66e-06	192	113	6	c3dda7c48732b0b8bde36de282d64192f5e9b98f
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ACR WNT2B BMPR2 PTPRB ADAMTS6 NAV3	1.02e-05	194	113	6	68004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCell	facs-Brain_Non-Myeloid-Cortex\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM229A GJB6 SREBF1 CLDN10 SLC44A1 GABBR1	1.09e-05	196	113	6	256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCell	cellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL7A1 CAPN1 CLDN10 GJB2 AOPEP PLEKHA5	1.18e-05	199	113	6	974f71b56f66243c78f2f297a1540e0e186df530
ToppCell	mLN-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	MRC1 NELFCD ARMCX3 SLC44A1 LRP1 USP15	1.22e-05	200	113	6	e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DPY19L3 CLDN10 TINAGL1 PTPRB SUV39H1 MOV10L1	1.22e-05	200	113	6	a8b59e6fe04271fef61db911a286b5c48438bb84
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT2_Precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	LPCAT1 SREBF1 CLDN10 PLA2G4F DNAH5	4.73e-05	155	113	5	9cad73d0b8ead289e1073d1a2e00bbeb1228308c
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D122\|Adult / Lineage, Cell type, age group and donor	ACR WNT2B TINAGL1 PTPRB ABCC8	5.50e-05	160	113	5	0cfe130606af433b2aa90e0a20b6c44659dd6fd4
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC5A7 TINAGL1 ADAMTS6 ABCC8 CTSZ	5.84e-05	162	113	5	c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC5A7 TINAGL1 ADAMTS6 ABCC8 CTSZ	5.84e-05	162	113	5	f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC5A7 TINAGL1 ADAMTS6 ABCC8 CTSZ	5.84e-05	162	113	5	5d902bb31e691aea9749617cc88303c2448f24b8
ToppCell	390C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NPR1 WNT2B CASP9 ADAMTS16 DNAH5	6.19e-05	164	113	5	2957065d7f1332c5280d47be7cc342286f84be3e
ToppCell	Basal_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	COL7A1 TINAGL1 AOPEP UGCG SNTG1	6.19e-05	164	113	5	85487a303194f5244956ec1ca2d1758d38117f41
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LPCAT1 PIGS CLDN10 TINAGL1 PLA2G4F	6.19e-05	164	113	5	fe11fcce4ba7f44ba2989ea3705916b67e75f8e7
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LPCAT1 PIGS CLDN10 TINAGL1 PLA2G4F	6.19e-05	164	113	5	b6beb8548ac0dd07e8a580a938e5ee4bf25a3c1f
ToppCell	390C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NPR1 WNT2B CASP9 ADAMTS16 DNAH5	6.19e-05	164	113	5	82e57d618c6e59bca4a03d31caf35b6043dfcf52
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NPR1 WNT2B BMPR2 PTPRB ADAMTS6	6.37e-05	165	113	5	a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCell	Ionocyte-iono-3\|World / Class top	COL7A1 CASP9 ZBED4 SUV39H1 RACGAP1	6.55e-05	166	113	5	9c4a780f8af46d7552077c7a0ae0ab1b2413e5d4
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL7A1 PCNX2 TMCO4 CHST4 SNTG1	6.74e-05	167	113	5	743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL7A1 PCNX2 TMCO4 CHST4 SNTG1	6.74e-05	167	113	5	1adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D231\|Adult / Lineage, Cell type, age group and donor	WNT2B CLDN10 PTPRB ADAMTS6 TACR3	6.93e-05	168	113	5	aca34c51758c65925ad24110294a72b2dea6db72
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM229A CLDN10 TINAGL1 ADAMTS16 PLD2	6.93e-05	168	113	5	100ab6d36592b61f4db9f8cb90c48afac016d679
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	MRC1 DPY19L3 ZBED4 CCDC28A-AS1 PLD2	7.96e-05	173	113	5	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCDHA11 RFX3 CFAP57 TMC5 DNAH5	7.96e-05	173	113	5	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL7A1 TMEM229A CASP9 CLDN10 GJB2	8.40e-05	175	113	5	3f1b2e23fec953148fb0711e523c463adb07dca4
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM229A CLDN10 TINAGL1 ADAMTS16 PLD2	8.40e-05	175	113	5	6bb8fc2959583644f16b22e906af91af62a3a633
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM229A CLDN10 TINAGL1 ADAMTS16 PLD2	8.40e-05	175	113	5	8902c38067f025b094ca9c28c449c32a66eded1c
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACR ABCB6 RFX3 TMCO4 SLIT1	8.63e-05	176	113	5	3766e0533b103ec92ac75eba3df02e287efc53fa
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACR ABCB6 RFX3 TMCO4 SLIT1	8.63e-05	176	113	5	aa1bada2175d8370fc71939a607407155259d195
ToppCell	facs-Pancreas-Exocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL7A1 TMEM229A CASP9 CLDN10 GJB2	9.35e-05	179	113	5	bbfbfb32773346080127055b5aafa36bbf7d0942
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SREBF1 XAB2 DNAH1 TMCO4 AOPEP	9.60e-05	180	113	5	62511d76d24b836839c3dcc2bf30485ffe9401e2
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 ARPC1B CRYBB1 LPCAT2 CTSZ	9.60e-05	180	113	5	a600bc705993d3a010550a25d3b54358946f061f
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_A2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	SREBF1 XAB2 DNAH1 TMCO4 AOPEP	1.01e-04	182	113	5	03992d0ae519795239e4f2cc8e63f33c4482de6a
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MRC1 NPR1 ITGA2B TINAGL1 UBTD1	1.01e-04	182	113	5	fc020d784ab81af80d9331cc322b7c259284eaef
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 PSEN2 CAPN1 LRP1 CTSZ	1.06e-04	184	113	5	fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 ACR TINAGL1 PTPRB RALGPS1	1.09e-04	185	113	5	742350093d90f96735dc73e3360cdd749bae63fd
ToppCell	Myeloid-B_(Activated_Macrophage)\|World / shred on cell class and cell subclass (v4)	MRC1 PSEN2 CAPN1 LRP1 CTSZ	1.12e-04	186	113	5	33d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined\|Fibroblasts / Location, Cell class and cell subclass	CAPN1 UBR7 UBTD1 LRP5 KYAT3	1.12e-04	186	113	5	403ac98f72a42721f84fbd7826f251a88ae534a2
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 PSEN2 CAPN1 LRP1 CTSZ	1.12e-04	186	113	5	7950e03ea080238c168b9d807e217f459acdfb28
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL7A1 MYO1E DSCAML1 AOPEP DNAH5	1.21e-04	189	113	5	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL7A1 MYO1E DSCAML1 AOPEP DNAH5	1.21e-04	189	113	5	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	wk_08-11-Endothelial-Lymph_endothelial-Lymphatic_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MRC1 NPR1 UNC5A UBTD1 PTPRB	1.24e-04	190	113	5	279c5f68b993dc7adbf9aa69fffb1321cdebc48a
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	WNT2B BMPR2 PTPRB ADAMTS6 ABCC8	1.24e-04	190	113	5	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	Control-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	BMPR2 PTPRB FAM177B ABCC8 UGCG	1.24e-04	190	113	5	4e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	RRAGA VPS13A PLEKHA5 TAF6 DNASE1	1.24e-04	190	113	5	2434b8ad2976eab7d9147012c28454ab29670709
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NPR1 TINAGL1 PTPRB ADAMTS6 PLD2	1.24e-04	190	113	5	d0297d678498e346e56cf95fe9e3db7d3ad3b837
ToppCell	wk_08-11-Endothelial-Lymph_endothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MRC1 NPR1 UNC5A UBTD1 PTPRB	1.24e-04	190	113	5	d7f1dc032d161529559e01832d1a3112c6f6cc1a
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	WNT2B CLDN10 TINAGL1 BMPR2 PTPRB	1.27e-04	191	113	5	50601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	MYO1E WNT2B CLDN10 BMPR2 PTPRB	1.27e-04	191	113	5	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	DIP2B SORCS1 AOPEP PLEKHA5 LARGE1	1.30e-04	192	113	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NPR1 TINAGL1 BMPR2 PTPRB ABCC8	1.33e-04	193	113	5	c0f0052c24b7fe9e21d2bc6c38047a8e755f87b6
ToppCell	(4)_Endothelial_cells\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	MRC1 NPR1 TINAGL1 PTPRB UGCG	1.33e-04	193	113	5	ae6ba13d4d9f2a700887cdda2790c32007b29ac8
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 NPR1 ACR TINAGL1 PTPRB	1.33e-04	193	113	5	4a8c97ff2dffc5c06351d1cb107e21e58250aa55
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TINAGL1 BMPR2 PTPRB ABCC8 NAV3	1.33e-04	193	113	5	9ba688b35a9ead5d04691b3f3f15484f02dbbd0d
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 NPR1 ACR TINAGL1 PTPRB	1.33e-04	193	113	5	d5f6d6e2c36d4e80af4d39cdfc0b18df295a587b
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJB6 CLDN10 GJB2 SLIT1 SOWAHB	1.33e-04	193	113	5	55eab7d2574e9cc2ed8f08e0a7ca7cbf90fb5818
ToppCell	IPF-Endothelial-VE_Venous\|IPF / Disease state, Lineage and Cell class	NPR1 TINAGL1 PTPRB ABCC8 NAV3	1.33e-04	193	113	5	29a655fa80feaabe846c90a28363b037e22d24ae
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NPR1 TINAGL1 BMPR2 PTPRB ABCC8	1.33e-04	193	113	5	682ce63b73a7d02eef240673db67058d7507f744
ToppCell	P15-Endothelial-large_vessel_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PSEN2 ARPC1B TINAGL1 PTPRB LPCAT2	1.33e-04	193	113	5	5f9a7cd5f8eb9ac294cdb50518fedf872f3f78f5
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BMPR2 PTPRB ADAMTS6 ABCC8 NAV3	1.33e-04	193	113	5	ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCell	Endothelial-A-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	ACR TINAGL1 PTPRB ABCC8 TACR3	1.36e-04	194	113	5	abea887dd472c1a0d572e690bc8914c1b94712ad
ToppCell	COPD-Endothelial-VE_Capillary_B\|COPD / Disease state, Lineage and Cell class	TINAGL1 BMPR2 PTPRB ABCC8 NAV3	1.36e-04	194	113	5	18b7f901c12ca4f21f9a1eafd092aefe4d668b6d
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	WNT2B BMPR2 PTPRB ADAMTS6 ABCC8	1.36e-04	194	113	5	40842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPR1 ARPC1B TINAGL1 UBTD1 PTPRB	1.36e-04	194	113	5	23f2a627226aaed468c55adc42ab22e051dfe7fe
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL7A1 MYO1E UGCG TENM1 DNAH5	1.40e-04	195	113	5	938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 NPR1 AGPAT5 TINAGL1 PTPRB	1.40e-04	195	113	5	12ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	WNT2B TINAGL1 BMPR2 PTPRB NAV3	1.40e-04	195	113	5	023e3c97dd3696d74f002ff8da0c04d876c82aef
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NPR1 TINAGL1 BMPR2 PTPRB ABCC8	1.40e-04	195	113	5	53b83e16b350100b1d5791a9c42bd98e37cbc0af
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPR1 ARPC1B TINAGL1 UBTD1 PTPRB	1.40e-04	195	113	5	752a100297c26732e12bbbf3ab27a2bd4f5ea06d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL7A1 MYO1E UGCG TENM1 DNAH5	1.40e-04	195	113	5	d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell	tumor_Lung-Endothelial_cells-Stalk-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	ARPC1B CLDN10 BMPR2 PTPRB LPCAT2	1.40e-04	195	113	5	56f88ce95495260360bf08f9c76cc36e395dc6a9
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	COL7A1 NPR1 WNT2B SORCS1 TINAGL1	1.40e-04	195	113	5	633c7668fe365f7b0f7851cdc442d5dd89c454e2
ToppCell	facs-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 NPR1 BMPR2 PTPRB LRP5	1.40e-04	195	113	5	7f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell	343B-Endothelial_cells-Endothelial-D\|343B / Donor, Lineage, Cell class and subclass (all cells)	TINAGL1 BMPR2 PTPRB ABCC8 CHST4	1.43e-04	196	113	5	99953fe0a40e242f6945150345fc0a08ed95f8f9
ToppCell	(01)_IL1RL1+-(1)_GFP\|(01)_IL1RL1+ / shred by cell type by condition	COL7A1 GJB6 CAPN1 ARPC1B GJB2	1.43e-04	196	113	5	b598b1112242534e139318012b257ed3cb09da83
ToppCell	droplet-Liver-LIVER-NPC-1m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 NPR1 ARPC1B TINAGL1 PTPRB	1.43e-04	196	113	5	0dfa2dc1ec527d40005614c00ed0e5f3a566c2e2
ToppCell	343B-Endothelial_cells-Endothelial-D-\|343B / Donor, Lineage, Cell class and subclass (all cells)	TINAGL1 BMPR2 PTPRB ABCC8 CHST4	1.43e-04	196	113	5	5edffdc4c1ff35d9ee0e5c1bed0dc0c90b76ea00
ToppCell	droplet-Tongue-nan-3m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJB6 CLDN10 GJB2 SLIT1 SOWAHB	1.43e-04	196	113	5	159061fd0961b2cfb5941d403acc5b395dd0d3a0
ToppCell	droplet-Liver-LIVER-NPC\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 NPR1 ARPC1B TINAGL1 PTPRB	1.43e-04	196	113	5	a3513c91afdc2d363e1c57071ae2399f9b7e6263
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CLDN10 TINAGL1 BMPR2 PTPRB LPCAT2	1.46e-04	197	113	5	61b1b10a017cbeb17f8529fcae66cba77ee2f115
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MRC1 NPR1 TINAGL1 PTPRB UGCG	1.46e-04	197	113	5	f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 NPR1 TINAGL1 BMPR2 PTPRB	1.46e-04	197	113	5	deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	LPCAT1 VPS13C AOPEP C5 DNAH5	1.46e-04	197	113	5	b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RFX3 VPS13A TENM1 SMARCA2 TCF25	1.46e-04	197	113	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NPR1 TINAGL1 BMPR2 PTPRB ABCC8	1.46e-04	197	113	5	8437c33e2c4a10a1b95343431e48d5e820b1f742
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 NPR1 TINAGL1 BMPR2 PTPRB	1.46e-04	197	113	5	a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NPR1 TINAGL1 BMPR2 PTPRB ABCC8	1.46e-04	197	113	5	0542badae77d2f606c13cfaf361319495c354351
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NPR1 TINAGL1 BMPR2 PTPRB ABCC8	1.46e-04	197	113	5	a6a64581699cfcb9607b288976fa3b09648725b7
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL7A1 CAPN1 GJB2 AOPEP PLEKHA5	1.50e-04	198	113	5	240e1aa0594ee6de530b2f97d5e392c5fcbf278b
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CLDN10 TINAGL1 BMPR2 PTPRB LPCAT2	1.50e-04	198	113	5	8a55589b9244283e4b0b423a4a6d6202e8e0fec9
ToppCell	cellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL7A1 SLC5A7 GJB2 AOPEP PLEKHA5	1.50e-04	198	113	5	7063d74d79f53d5c59c853a2575f9d3ef12f19ea
Disease	Keratitis-Ichthyosis-Deafness Syndrome	GJB6 GJB2	1.43e-05	2	112	2	C3665333
Disease	Senter syndrome	GJB6 GJB2	1.43e-05	2	112	2	C0265336
Disease	autosomal recessive nonsyndromic deafness 1A (implicated_via_orthology)	GJB6 GJB2	1.43e-05	2	112	2	DOID:0110475 (implicated_via_orthology)
Disease	DFNA 3 Nonsyndromic Hearing Loss and Deafness	GJB6 GJB2	1.43e-05	2	112	2	cv:CN043589
Disease	autosomal recessive nonsyndromic deafness 1A (is_implicated_in)	GJB6 GJB2	1.43e-05	2	112	2	DOID:0110475 (is_implicated_in)
Disease	Parkinson's disease 23 (implicated_via_orthology)	VPS13C VPS13A	1.43e-05	2	112	2	DOID:0060896 (implicated_via_orthology)
Disease	choreaacanthocytosis (implicated_via_orthology)	VPS13C VPS13A	1.43e-05	2	112	2	DOID:0050766 (implicated_via_orthology)
Disease	visual epilepsy (biomarker_via_orthology)	GJB6 ABCC8 TACR3 PLD2 GABBR1	2.45e-05	90	112	5	DOID:11832 (biomarker_via_orthology)
Disease	DEAFNESS, AUTOSOMAL RECESSIVE 1A	GJB6 GJB2	4.27e-05	3	112	2	220290
Disease	autosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)	VPS13C VPS13A	4.27e-05	3	112	2	DOID:0111611 (implicated_via_orthology)
Disease	DEAFNESS, X-LINKED 2	GJB6 GJB2	4.27e-05	3	112	2	304400
Disease	Cohen syndrome (implicated_via_orthology)	VPS13C VPS13A	4.27e-05	3	112	2	DOID:0111590 (implicated_via_orthology)
Disease	Deafness, autosomal dominant nonsyndromic sensorineural 3	GJB6 GJB2	4.27e-05	3	112	2	cv:
Disease	Progressive hearing loss stapes fixation	GJB6 GJB2	4.27e-05	3	112	2	C1844678
Disease	DEAFNESS, DIGENIC, GJB2/GJB6 (disorder)	GJB6 GJB2	4.27e-05	3	112	2	C2673760
Disease	DEAFNESS, DIGENIC, GJB2/GJB3 (disorder)	GJB6 GJB2	4.27e-05	3	112	2	C2673761
Disease	DEAFNESS, AUTOSOMAL RECESSIVE 1A (disorder)	GJB6 GJB2	4.27e-05	3	112	2	C2673759
Disease	X-linked mixed hearing loss with perilymphatic gusher	GJB6 GJB2	4.27e-05	3	112	2	cv:C1844678
Disease	Autosomal recessive nonsyndromic hearing loss 1A	GJB6 GJB2	4.27e-05	3	112	2	cv:C2673759
Disease	Hidrotic Ectodermal Dysplasia	GJB6 GJB2	1.42e-04	5	112	2	C0162361
Disease	Colorectal Carcinoma	COL7A1 RNPEPL1 ABCB6 DSCAML1 SIGLEC7 ABCC8 VPS13A TENM1 LRP1 VRTN	3.49e-04	702	112	10	C0009402
Disease	cerebellar ataxia (implicated_via_orthology)	VPS13C VPS13A	3.94e-04	8	112	2	DOID:0050753 (implicated_via_orthology)
Disease	CATARACT, COPPOCK-LIKE	CRYBB1 CRYBB2	5.05e-04	9	112	2	C1852438
Disease	Cataract microcornea syndrome	CRYBB1 CRYBB2	5.05e-04	9	112	2	C1861829
Disease	Cataract, Pulverulent	CRYBB1 CRYBB2	5.05e-04	9	112	2	C1833118
Disease	fish oil supplement exposure measurement, triglyceride measurement	GJB6 GJB2	6.30e-04	10	112	2	EFO_0004530, EFO_0600007
Disease	papillary thyroid carcinoma	PCNX2 SOWAHB	9.19e-04	12	112	2	EFO_0000641
Disease	superior frontal gyrus grey matter volume measurement	SMARCA2 SNTG1	1.26e-03	14	112	2	EFO_0006516
Disease	thyroid volume	SMARCA2 DNAH5	1.65e-03	16	112	2	EFO_0004865
Disease	Nuclear non-senile cataract	CRYBB1 CRYBB2	2.10e-03	18	112	2	C1112705
Disease	Nuclear cataract	CRYBB1 CRYBB2	2.10e-03	18	112	2	C0392557
Disease	urate measurement	COL7A1 CAPN1 CASP9 CLDN10 DNAH1 STPG4 BMPR2 LRP1 DNASE1 LARGE1	2.19e-03	895	112	10	EFO_0004531
Disease	synophrys measurement	TCF25 LRP5 HTT	2.23e-03	68	112	3	EFO_0007906
Disease	cortical surface area change measurement, age at assessment	VRTN USP15	2.34e-03	19	112	2	EFO_0008007, EFO_0021503
Disease	unipolar depression, response to bupropion, mood disorder	ADAMTS6 NAV3	2.34e-03	19	112	2	EFO_0003761, EFO_0004247, EFO_0006326
Disease	kidney disease (biomarker_via_orthology)	SREBF1 CASP9	2.86e-03	21	112	2	DOID:557 (biomarker_via_orthology)
Disease	response to diuretic	NELFCD CTSZ	3.43e-03	23	112	2	GO_0036270

Protein segments in the cluster

Peptide	Gene	Start	Entry
ESDGKSRWFYSPWLL	ARMT1	101	Q9H993
KGEYPRWDSWTSSRR	CRYBB2	76	P43320
PWGERGWLRIVTSTY	CTSZ	266	Q9UBR2
TATWPYLNWIASKIG	ACR	276	P10323
AYVWTLKGRTWKPTL	ARPC1B	76	O15143
LPSSWDYRWNLTLSP	CCDC28A-AS1	46	A0A096LPI5
YFLLRDLPSWSSVDW	FBXO4	101	Q9UKT5
WASALWYLSITRPTS	B3GALT1	16	Q9Y5Z6
LEKGEYPRWNTWSSS	CRYBB1	116	P53674
KAPWNSLAWTVTSYV	ABCB6	296	Q9NP58
IWYKTKPEGRSVTWT	AOPEP	246	Q8N6M6
VRIEGSLWWTYTSSI	GJB2	126	P29033
VTALYITSWLLSGTW	DPY19L3	171	Q6ZPD9
LPLANTSYPWSWARV	NPR1	41	P16066
RTIRKWNTTLYEGTW	CAPN1	361	P07384
SGWVLVSSTLPTDYW	CLDN10	16	P78369
KSIVWYPPWARIGTE	ARMCX3	71	Q9UH62
WTVDWPGRYKFSGTT	ADAMTS16	801	Q8TE57
DFTRSGKPWWLNDTS	ADAMTS6	211	Q9UKP5
GKPWWLNDTSTVSYS	ADAMTS6	216	Q9UKP5
EGRKPALSSWTRYWV	RALGPS1	446	Q5JS13
ALSSWTRYWVILSGS	RALGPS1	451	Q5JS13
SLNYWRTWKCISKPS	KCTD19	126	Q17RG1
LYTALWWSATPTEGA	PCDHA11	716	Q9Y5I1
QTKWPYIELLWTTDR	MINDY3	426	Q9H8M7
WWTPSSGKVTSYEVQ	PTPRB	131	P23467
LRYPNKLDTITWTWQ	LPCAT1	236	Q8NF37
KWRTATTPYRVEWEA	LARGE1	641	O95461
WVEAEYRIRPGTWSS	MOV10L1	156	Q9BXT6
EWLVRKFFGSLPDSW	HTATIP2	181	Q9BUP3
IRYPNSLDTTSWAWR	LPCAT4	231	Q643R3
GVLKWVDWTVSEPRY	NELFCD	426	Q8IXH7
WPWSGYLAISISVTK	MBTPS1	556	Q14703
WRKTLEPWKLYATVG	GABBR1	701	Q9UBS5
WTNWHTGTISYRSLP	LRP1	3916	Q07954
TSPPESNLVYWLWEK	CFAP57	126	Q96MR6
SGDTLYWTDWQTRSI	LRP5	246	O75197
LDPSKLSWGPYLRFW	FAM177B	56	A6PVY3
GPITLDRIRTWFWTK	PCNX2	1851	A6NKB5
KWVLDTYPWSSATLP	NAV3	2291	Q8IVL0
GWPRLKWVVTDSKYL	DIP2B	481	Q9P265
GSTWCISTLYRDPAW	PLA2G4F	396	Q68DD2
PNKLDTVTWTWQGYT	LPCAT2	251	Q7L5N7
QPYLDLWTTASDWLR	DNAH1	1021	Q9P2D7
NSYTRVPPLVWKLGW	HTT	2406	P42858
LQSFYPWEWGEKRIS	ERVK-7	196	P61567
TAIVLEYRPKGTWAW	DSCAML1	1511	Q8TD84
SYVRPSQWSSIRLWT	DNASE1	196	P24855
VRIEGSLWWTYTSSI	GJB6	126	O95452
FVSWRDPKSGSWYVE	CASP9	351	P55211
SKPEIRSYFPESWLW	C5	761	P01031
KTPYSLKRWRPSTWV	BMPR2	976	Q13873
SALWDPTISWRTGRY	UGCG	366	Q16739
ISRGWYPKPLTVWRD	BTN2A1	166	Q7KYR7
YLNLDTWTWSGRITI	KLHDC1	226	Q8N7A1
TGVLWWLYAKQRRSP	SLC44A1	256	Q8WWI5
WTPVSRASSYILSWR	COL7A1	976	Q02388
ALVPSVWLYWRGASS	C3orf56	96	Q8N813
KPVYGKRWSSSDWTL	KYAT3	181	Q6YP21
DWTDGIFSTLWRKTL	DNAH5	2311	Q8TE73
EWSDGTPVTFTKWLR	MRC1	436	P22897
GLPLWWKTTETYRAS	PIGS	31	Q96S52
RKYTKPEAIIGSWLW	GPRASP1	711	Q5JY77
SATGPKSVWYRIAFW	HRH4	331	Q9H3N8
KPWLGTVDSSEVYSW	SLC5A7	226	Q9GZV3
KSWVDEKTPWTTRYG	TAF6	361	P49848
SWLDKSTPYTAVRWV	RER1	31	O15258
ILRYTSTDAPAIWWL	RNPEPL1	166	Q9HAU8
SLFKWPNVSDIWSTY	XAB2	546	Q9HCS7
RTLKYWTAANSWGPA	TINAGL1	416	Q9GZM7
PLSTLSNWTYEFDKW	SMARCA2	781	P51531
WLASGKYRTFSAPWA	TMCO4	286	Q5TGY1
SRGWGTWKRVPIYVI	TMEM229A	301	B2RXF0
PTRYSWKKGVWLTDL	MMP23B	191	O75900
IEKLWQTFWRYSPST	RFX3	376	P48380
YKFLAPPVTTWDWTR	SNTG1	316	Q9NSN8
WTTTPRSNWEIYRKP	PIRT	41	P0C851
WRLKGSLSRGDWYKT	NDUFV1	51	P49821
TPYSWVRFEWKPASS	PTDSS2	296	Q9BVG9
LSWTWRSLTLYPSQP	SIGLEC7	286	Q9Y286
IISRTWADGKIWSYT	TENM1	1871	Q9UKZ4
WRSDTPLIYKAVPSW	IARS1	401	P41252
TTEYVVGAPTWSWTL	ITGA2B	281	P08514
PSWRIALWSLAYGVV	TACR3	81	P29371
YWTRSRRKTGTLQPW	RACGAP1	241	Q9H0H5
KPWQYLTSNTSGEIW	SOWAHB	706	A6NEL2
PLPSDWWESYLKRTI	POM121L2	91	Q96KW2
LVKWRGYPDSESTWE	SUV39H1	61	O43463
DWSVLSTPWESLYSL	SREBF1	776	P36956
YWLAKWTDSALTLTP	ABCC8	1031	Q09428
PLPWTWVRSYEFTSN	CCL26	41	Q9Y258
SLTAFYPRAVISWWS	CLN3	171	Q13286
SQAWRWSLPYEKVSR	CHST4	331	Q8NCG5
IWTKRDIRPDFGSWT	PGBD2	111	Q6P3X8
EIKEAVSSLPSYWSW	TMEM95	76	Q3KNT9
VSSLPSYWSWLRKTK	TMEM95	81	Q3KNT9
FYTWADPVGSRRLKW	VPS13A	2446	Q96RL7
TWKTYNPAFSRLEIW	TMEM181	301	Q9P2C4
WWRIALTDTPIPGTY	STPG4	41	Q8N801
RTSIWDETLYKAWSS	RRAGA	161	Q7L523
LLPTEGWNKLVSWYT	USP15	91	Q9Y4E8
YLPEWSAWVILGAIS	PSEN2	246	P49810
WADPTGTRKLTWTYA	VPS13C	3011	Q709C8
PSWQRWFFSGKLLTD	UBTD1	186	Q9HAC8
AVIVYVDGSWSPWSK	UNC5A	236	Q6ZN44
TATYWPLNWRSKLCT	UBR7	301	Q8N806
WIDTLSTRPGYLWVV	TMC5	881	Q6UXY8
PTYVLAWGVWRLLSA	AGPAT5	26	Q9NUQ2
LRYPSLSPSAFWVWK	VRTN	531	Q9H8Y1
LSPSAFWVWKSLARG	VRTN	536	Q9H8Y1
NLEWISLPRSWTYGI	PLEKHA5	6	Q9HAU0
AVLWPSQVGTLTYVW	SORCS1	911	Q8WY21
WLSSWVKTGYKEPGI	SLIT1	876	O75093
RAGIWTKTHTIWYKP	TRIP12	1386	Q14669
ITDWWLSPEVYLKRP	PLD2	361	O14939
CTWLTTPKSTWPRYS	TCF25	216	Q9BQ70
TLPARVDTSWWYIGA	WNT2B	51	Q93097
LTYWNLKKASWPGLS	ZBED4	1101	O75132
YAILTKATWPSWQGE	MYO1E	636	Q12965