Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	potassium:proton antiporter activity	SLC9A4 SLC9A2 SLC9A3 SLC9A6	4.34e-08	14	53	4	GO:0015386
GeneOntologyMolecularFunction	sodium:proton antiporter activity	SLC9A4 SLC9A2 SLC9A3 SLC9A6	7.86e-08	16	53	4	GO:0015385
GeneOntologyMolecularFunction	transporter activity	GJA8 SLC9A4 SLC9A2 SLC9A3 ATP8B4 HTR1B ATP11B XKR9 ABCA5 SLC26A7 SLC43A1 TCIRG1 KCNQ1 SLC9A6 MFSD10 SLC2A3	1.26e-07	1289	53	16	GO:0005215
GeneOntologyMolecularFunction	solute:potassium antiporter activity	SLC9A4 SLC9A2 SLC9A3 SLC9A6	1.66e-07	19	53	4	GO:0022821
GeneOntologyMolecularFunction	metal cation:proton antiporter activity	SLC9A4 SLC9A2 SLC9A3 SLC9A6	7.42e-07	27	53	4	GO:0051139
GeneOntologyMolecularFunction	transmembrane transporter activity	GJA8 SLC9A4 SLC9A2 SLC9A3 HTR1B ATP11B ABCA5 SLC26A7 SLC43A1 TCIRG1 KCNQ1 SLC9A6 MFSD10 SLC2A3	1.60e-06	1180	53	14	GO:0022857
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	FADS1 FADS3 FADS2	4.96e-06	13	53	3	GO:0016717
GeneOntologyMolecularFunction	metal cation:monoatomic cation antiporter activity	SLC9A4 SLC9A2 SLC9A3 SLC9A6	5.05e-06	43	53	4	GO:0140828
GeneOntologyMolecularFunction	linoleoyl-CoA desaturase activity	FADS1 FADS2	6.91e-06	2	53	2	GO:0016213
GeneOntologyMolecularFunction	antiporter activity	SLC9A4 SLC9A2 SLC9A3 SLC26A7 SLC9A6	3.22e-05	138	53	5	GO:0015297
GeneOntologyMolecularFunction	acyl-CoA desaturase activity	FADS1 FADS2	6.88e-05	5	53	2	GO:0016215
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	SLC9A4 SLC9A2 SLC9A3 KCNQ1 SLC9A6	7.99e-05	167	53	5	GO:0015079
GeneOntologyMolecularFunction	proton transmembrane transporter activity	SLC9A4 SLC9A2 SLC9A3 TCIRG1 SLC9A6	1.40e-04	188	53	5	GO:0015078
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC9A4 SLC9A2 SLC9A3 SLC26A7 TCIRG1 SLC9A6	1.41e-04	301	53	6	GO:0022853
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC9A4 SLC9A2 SLC9A3 HTR1B ATP11B SLC26A7 TCIRG1 KCNQ1 SLC9A6	2.17e-04	793	53	9	GO:0015075
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC9A4 SLC9A2 SLC9A3 ABCA5 SLC26A7 TCIRG1 SLC9A6	2.53e-04	477	53	7	GO:0022804
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ATP8B4 ATP11B XKR9	3.36e-04	51	53	3	GO:0140303
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC9A4 SLC9A2 SLC9A3 HTR1B SLC26A7 TCIRG1 KCNQ1 SLC9A6	8.11e-04	758	53	8	GO:0015318
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC9A4 SLC9A2 SLC9A3 SLC9A6	1.10e-03	171	53	4	GO:0015081
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC9A4 SLC9A2 SLC9A3 SLC26A7 SLC9A6	1.11e-03	296	53	5	GO:0015291
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC9A4 SLC9A2 SLC9A3 HTR1B TCIRG1 KCNQ1 SLC9A6	1.28e-03	627	53	7	GO:0022890
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC9A4 SLC9A2 SLC9A3 HTR1B KCNQ1 SLC9A6	1.40e-03	465	53	6	GO:0046873
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC9A4 SLC9A2 SLC9A3 HTR1B TCIRG1 KCNQ1 SLC9A6	1.78e-03	664	53	7	GO:0008324
GeneOntologyMolecularFunction	lipid transporter activity	ATP8B4 ATP11B XKR9 ABCA5	1.81e-03	196	53	4	GO:0005319
GeneOntologyMolecularFunction	G protein-coupled receptor activity	HTR1B GPR68 OR1S1 OR1L6 OR5K2 OR8B12 OR52W1 GPR171	2.16e-03	884	53	8	GO:0004930
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ATP8B4 ATP11B	2.50e-03	28	53	2	GO:0140326
GeneOntologyMolecularFunction	olfactory receptor activity	OR1S1 OR1L6 OR5K2 OR8B12 OR52W1	5.61e-03	431	53	5	GO:0004984
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC26A7 SLC43A1 MFSD10 SLC2A3	7.57e-03	293	53	4	GO:0008514
GeneOntologyMolecularFunction	actin binding	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31C1 SPATA31A5	8.67e-03	479	53	5	GO:0003779
GeneOntologyBiologicalProcess	sodium ion import across plasma membrane	SLC9A4 SLC9A2 SLC9A3 SLC9A6	6.52e-07	27	53	4	GO:0098719
GeneOntologyBiologicalProcess	import across plasma membrane	SLC9A4 SLC9A2 SLC9A3 SLC43A1 KCNQ1 SLC9A6 SLC2A3	1.95e-06	230	53	7	GO:0098739
GeneOntologyBiologicalProcess	regulation of intracellular pH	SLC9A4 SLC9A2 SLC9A3 TCIRG1 SLC9A6	4.26e-06	94	53	5	GO:0051453
GeneOntologyBiologicalProcess	regulation of cellular pH	SLC9A4 SLC9A2 SLC9A3 TCIRG1 SLC9A6	6.07e-06	101	53	5	GO:0030641
GeneOntologyBiologicalProcess	gastric acid secretion	SLC9A4 SLC26A7 KCNQ1	8.76e-06	16	53	3	GO:0001696
GeneOntologyBiologicalProcess	unsaturated fatty acid biosynthetic process	FADS1 FADS3 FADS2 ELOVL7	1.29e-05	56	53	4	GO:0006636
GeneOntologyBiologicalProcess	acid secretion	SLC9A4 HTR1B SLC26A7 KCNQ1	1.39e-05	57	53	4	GO:0046717
GeneOntologyBiologicalProcess	regulation of pH	SLC9A4 SLC9A2 SLC9A3 TCIRG1 SLC9A6	1.41e-05	120	53	5	GO:0006885
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	SLC9A4 SLC9A2 SLC9A3 KCNQ1 SLC9A6 NEDD4	1.51e-05	208	53	6	GO:0035725
GeneOntologyBiologicalProcess	potassium ion transmembrane transport	SLC9A4 SLC9A2 SLC9A3 KCNQ1 SLC9A6 NEDD4	2.80e-05	232	53	6	GO:0071805
GeneOntologyBiologicalProcess	inorganic ion import across plasma membrane	SLC9A4 SLC9A2 SLC9A3 KCNQ1 SLC9A6	3.17e-05	142	53	5	GO:0099587
GeneOntologyBiologicalProcess	inorganic cation import across plasma membrane	SLC9A4 SLC9A2 SLC9A3 KCNQ1 SLC9A6	3.17e-05	142	53	5	GO:0098659
GeneOntologyBiologicalProcess	potassium ion transport	SLC9A4 SLC9A2 SLC9A3 KCNQ1 SLC9A6 NEDD4	6.79e-05	272	53	6	GO:0006813
GeneOntologyBiologicalProcess	sodium ion transport	SLC9A4 SLC9A2 SLC9A3 KCNQ1 SLC9A6 NEDD4	7.22e-05	275	53	6	GO:0006814
GeneOntologyBiologicalProcess	import into cell	GPM6B SLC9A4 SLC9A2 SLC9A3 HTR1B XKR9 SLC43A1 KCNQ1 SLC9A6 SLC2A3 NEDD4	7.35e-05	1074	53	11	GO:0098657
GeneOntologyBiologicalProcess	proton transmembrane transport	SLC9A4 SLC9A2 SLC9A3 TCIRG1 SLC9A6	7.47e-05	170	53	5	GO:1902600
GeneOntologyBiologicalProcess	fatty acid biosynthetic process	FADS1 FADS3 TECR FADS2 ELOVL7	1.29e-04	191	53	5	GO:0006633
GeneOntologyBiologicalProcess	alpha-linolenic acid metabolic process	FADS1 FADS2	2.88e-04	10	53	2	GO:0036109
GeneOntologyBiologicalProcess	unsaturated fatty acid metabolic process	FADS1 FADS3 FADS2 ELOVL7	3.27e-04	128	53	4	GO:0033559
GeneOntologyBiologicalProcess	iodide transport	SLC26A7 KCNQ1	3.51e-04	11	53	2	GO:0015705
GeneOntologyBiologicalProcess	phospholipid translocation	ATP8B4 ATP11B XKR9	3.82e-04	55	53	3	GO:0045332
GeneOntologyBiologicalProcess	lipid translocation	ATP8B4 ATP11B XKR9	4.94e-04	60	53	3	GO:0034204
GeneOntologyBiologicalProcess	very long-chain fatty acid biosynthetic process	TECR ELOVL7	4.96e-04	13	53	2	GO:0042761
GeneOntologyBiologicalProcess	monocarboxylic acid biosynthetic process	FADS1 FADS3 TECR FADS2 ELOVL7	5.36e-04	260	53	5	GO:0072330
GeneOntologyBiologicalProcess	regulation of membrane lipid distribution	ATP8B4 ATP11B XKR9	6.25e-04	65	53	3	GO:0097035
GeneOntologyBiologicalProcess	fatty acid elongation	TECR ELOVL7	6.66e-04	15	53	2	GO:0030497
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	SLC9A4 SLC9A2 SLC9A3 HTR1B TCIRG1 KCNQ1 SLC9A6	1.01e-03	622	53	7	GO:0006873
GeneOntologyBiologicalProcess	long-chain fatty-acyl-CoA biosynthetic process	TECR ELOVL7	1.08e-03	19	53	2	GO:0035338
GeneOntologyCellularComponent	secretory granule	SLC9A4 ATP8B4 ARSB SPATA31A1 SPATA31A3 ATP11B SPATA31A7 TCIRG1 KCNQ1 SPATA31C1 SPATA31A5 SLC2A3	8.25e-06	1014	54	12	GO:0030141
GeneOntologyCellularComponent	acrosomal vesicle	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31C1 SPATA31A5 SLC2A3	1.48e-05	206	54	6	GO:0001669
GeneOntologyCellularComponent	secretory vesicle	SLC9A4 ATP8B4 ARSB SPATA31A1 SPATA31A3 ATP11B SPATA31A7 TCIRG1 KCNQ1 SPATA31C1 SPATA31A5 SLC2A3	6.33e-05	1246	54	12	GO:0099503
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	SLC9A4 SLC9A3 ATP8B4 ATP11B ABCA5 SLC26A7 TCIRG1 KCNQ1 SLC9A6 MFSD10 SLC2A3 SNX13	1.00e-04	1307	54	12	GO:0030659
GeneOntologyCellularComponent	vesicle membrane	SLC9A4 SLC9A3 ATP8B4 ATP11B ABCA5 SLC26A7 TCIRG1 KCNQ1 SLC9A6 MFSD10 SLC2A3 SNX13	1.14e-04	1325	54	12	GO:0012506
GeneOntologyCellularComponent	secretory granule membrane	SLC9A4 ATP8B4 ATP11B TCIRG1 KCNQ1 SLC2A3	1.99e-04	329	54	6	GO:0030667
GeneOntologyCellularComponent	recycling endosome membrane	SLC9A3 ATP11B SLC26A7 SLC9A6	2.01e-04	112	54	4	GO:0055038
GeneOntologyCellularComponent	apical plasma membrane	SLC9A4 SLC9A2 SLC9A3 SLC26A7 SLC43A1 TCIRG1 KCNQ1	2.45e-04	487	54	7	GO:0016324
GeneOntologyCellularComponent	endoplasmic reticulum membrane	EMC6 ESYT3 FADS1 FADS3 UGT1A6 TECR SLC43A1 FADS2 SLC9A6 ELOVL7 RIC3	3.96e-04	1293	54	11	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	EMC6 ESYT3 FADS1 FADS3 UGT1A6 TECR SLC43A1 FADS2 SLC9A6 ELOVL7 RIC3	4.12e-04	1299	54	11	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	EMC6 ESYT3 FADS1 FADS3 UGT1A6 TECR SLC43A1 FADS2 SLC9A6 ELOVL7 RIC3	4.93e-04	1327	54	11	GO:0042175
GeneOntologyCellularComponent	phospholipid-translocating ATPase complex	ATP8B4 ATP11B	5.84e-04	14	54	2	GO:1990531
GeneOntologyCellularComponent	apical part of cell	SLC9A4 SLC9A2 SLC9A3 SLC26A7 SLC43A1 TCIRG1 KCNQ1	7.87e-04	592	54	7	GO:0045177
GeneOntologyCellularComponent	endosome membrane	SLC9A3 ATP11B ABCA5 SLC26A7 TCIRG1 SLC9A6 SNX13	8.68e-04	602	54	7	GO:0010008
GeneOntologyCellularComponent	zymogen granule membrane	SLC9A4 KCNQ1	1.21e-03	20	54	2	GO:0042589
GeneOntologyCellularComponent	early endosome membrane	SLC9A3 ATP11B SLC9A6 SNX13	2.19e-03	212	54	4	GO:0031901
GeneOntologyCellularComponent	recycling endosome	SLC9A3 ATP11B SLC26A7 SLC9A6	2.58e-03	222	54	4	GO:0055037
GeneOntologyCellularComponent	zymogen granule	SLC9A4 KCNQ1	3.09e-03	32	54	2	GO:0042588
MousePheno	abnormal gastric parietal cell morphology	SLC9A4 SLC9A2 KCNQ1 FOXL1	5.32e-07	26	36	4	MP:0004139
MousePheno	hypochlorhydria	SLC9A4 SLC9A2 KCNQ1	5.45e-07	7	36	3	MP:0008001
MousePheno	abnormal gastric gland morphology	SLC9A4 SLC9A2 KCNQ1 FOXL1	1.63e-06	34	36	4	MP:0003892
MousePheno	abnormal digestive secretion	SLC9A4 SLC9A2 KCNQ1 FOXL1	1.83e-06	35	36	4	MP:0000501
MousePheno	abnormal gastric chief cell morphology	SLC9A4 KCNQ1 FOXL1	1.48e-05	19	36	3	MP:0004140
MousePheno	abnormal stomach glandular epithelium morphology	SLC9A4 SLC9A2 FOXL1	1.48e-05	19	36	3	MP:0000473
MousePheno	abnormal stomach morphology	SLC9A4 SLC9A2 SMCHD1 TECR KCNQ1 FOXL1	3.66e-05	248	36	6	MP:0000470
MousePheno	abnormal mucous neck cell morphology	SLC9A4 KCNQ1	3.86e-05	4	36	2	MP:0004138
MousePheno	abnormal stomach mucosa morphology	SLC9A4 SLC9A2 KCNQ1 FOXL1	4.38e-05	77	36	4	MP:0010792
MousePheno	abnormal stomach wall morphology	SLC9A4 SLC9A2 KCNQ1 FOXL1	5.10e-05	80	36	4	MP:0010783
MousePheno	digestive/alimentary phenotype	FOXE1 SLC9A4 SLC9A2 SLC9A3 FADS1 SLC26A7 SMCHD1 TECR HS2ST1 FADS2 KCNQ1 FOXL1 NEDD4	5.11e-05	1500	36	13	MP:0005381
MousePheno	abnormal thyroid gland morphology	FOXE1 ABCA5 SLC26A7 TCIRG1	7.08e-05	87	36	4	MP:0000681
MousePheno	abnormal stomach epithelium morphology	SLC9A4 SLC9A2 FOXL1	1.06e-04	36	36	3	MP:0000471
MousePheno	athyroidism	FOXE1 ABCA5	1.34e-04	7	36	2	MP:0004663
MousePheno	absent thyroid gland	FOXE1 ABCA5	1.34e-04	7	36	2	MP:0005314
MousePheno	abnormal digestion	SLC9A4 SLC9A2 KCNQ1 FOXL1	1.47e-04	105	36	4	MP:0001664
MousePheno	abnormal gastric surface mucous cell morphology	SLC9A4 KCNQ1	1.79e-04	8	36	2	MP:0004137
MousePheno	abnormal digestive system morphology	FOXE1 SLC9A4 SLC9A2 SLC9A3 SMCHD1 TECR HS2ST1 FADS2 KCNQ1 FOXL1 NEDD4	1.82e-04	1233	36	11	MP:0000462
MousePheno	renal tubular acidosis	SLC9A3 SLC26A7	2.30e-04	9	36	2	MP:0000525
MousePheno	increased stomach mucosa thickness	KCNQ1 FOXL1	2.30e-04	9	36	2	MP:0005211
MousePheno	stomach mucosa hyperplasia	KCNQ1 FOXL1	3.50e-04	11	36	2	MP:0010799
MousePheno	decreased prostaglandin level	FADS1 FADS2	4.94e-04	13	36	2	MP:0009815
MousePheno	abnormal blood pH regulation	SLC9A3 SLC26A7	4.94e-04	13	36	2	MP:0003027
MousePheno	abnormal digestive system physiology	SLC9A4 SLC9A2 SLC9A3 FADS1 SLC26A7 KCNQ1 FOXL1	7.22e-04	599	36	7	MP:0001663
MousePheno	increased circulating thyroid-stimulating hormone level	FOXE1 SLC26A7	8.56e-04	17	36	2	MP:0005122
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31C2 SPATA31C1 SPATA31A5	1.18e-10	12	53	5	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31C2 SPATA31C1 SPATA31A5	1.18e-10	12	53	5	IPR027970
Domain	NaH_exchanger	SLC9A4 SLC9A2 SLC9A3 SLC9A6	7.20e-09	9	53	4	IPR004709
Domain	Cation/H_exchanger_CPA1	SLC9A4 SLC9A2 SLC9A3 SLC9A6	1.88e-08	11	53	4	IPR018422
Domain	Fatty_acid_desaturase	FADS1 FADS3 FADS2	2.16e-08	3	53	3	IPR012171
Domain	Na_H_Exchanger	SLC9A4 SLC9A2 SLC9A3 SLC9A6	5.66e-08	14	53	4	PF00999
Domain	Cation/H_exchanger	SLC9A4 SLC9A2 SLC9A3 SLC9A6	5.66e-08	14	53	4	IPR006153
Domain	FA_desaturase_dom	FADS1 FADS3 FADS2	1.20e-06	8	53	3	IPR005804
Domain	FA_desaturase	FADS1 FADS3 FADS2	1.20e-06	8	53	3	PF00487
Domain	CYTOCHROME_B5_2	FADS1 FADS3 FADS2	6.05e-06	13	53	3	PS50255
Domain	CYTOCHROME_B5_1	FADS1 FADS3 FADS2	6.05e-06	13	53	3	PS00191
Domain	Cyt-b5	FADS1 FADS3 FADS2	7.68e-06	14	53	3	PF00173
Domain	Cyt_B5-like_heme/steroid-bd	FADS1 FADS3 FADS2	7.68e-06	14	53	3	IPR001199
Domain	Cyt-b5	FADS1 FADS3 FADS2	7.68e-06	14	53	3	SM01117
Domain	-	FADS1 FADS3 FADS2	7.68e-06	14	53	3	3.10.120.10
Domain	Na/H_exchanger_2	SLC9A4 SLC9A2	7.90e-06	2	53	2	IPR001953
Domain	NEXCaM_BD	SLC9A4 SLC9A2	2.37e-05	3	53	2	PF16644
Domain	NHE_CaM-bd	SLC9A4 SLC9A2	2.37e-05	3	53	2	IPR032103
Domain	GPCR_Rhodpsn_7TM	HTR1B GPR68 OR1S1 OR1L6 OR5K2 OR8B12 OR52W1 GPR171	5.59e-04	670	53	8	IPR017452
Domain	7tm_1	HTR1B GPR68 OR1S1 OR1L6 OR5K2 OR8B12 OR52W1 GPR171	5.99e-04	677	53	8	PF00001
Domain	G_PROTEIN_RECEP_F1_1	HTR1B GPR68 OR1S1 OR1L6 OR5K2 OR8B12 OR52W1 GPR171	6.47e-04	685	53	8	PS00237
Domain	G_PROTEIN_RECEP_F1_2	HTR1B GPR68 OR1S1 OR1L6 OR5K2 OR8B12 OR52W1 GPR171	6.85e-04	691	53	8	PS50262
Domain	GPCR_Rhodpsn	HTR1B GPR68 OR1S1 OR1L6 OR5K2 OR8B12 OR52W1 GPR171	6.92e-04	692	53	8	IPR000276
Domain	P_typ_ATPase_c	ATP8B4 ATP11B	7.03e-04	14	53	2	IPR032630
Domain	P-type_ATPase_N	ATP8B4 ATP11B	7.03e-04	14	53	2	IPR032631
Domain	P-type_ATPase_IV	ATP8B4 ATP11B	7.03e-04	14	53	2	IPR006539
Domain	PhoLip_ATPase_C	ATP8B4 ATP11B	7.03e-04	14	53	2	PF16212
Domain	PhoLip_ATPase_N	ATP8B4 ATP11B	7.03e-04	14	53	2	PF16209
Domain	-	ATP8B4 ATP11B	3.71e-03	32	53	2	2.70.150.10
Domain	-	ATP8B4 ATP11B	3.71e-03	32	53	2	3.40.1110.10
Domain	ATPase_P-typ_cyto_domN	ATP8B4 ATP11B	4.43e-03	35	53	2	IPR023299
Domain	ATPase_P-typ_P_site	ATP8B4 ATP11B	4.68e-03	36	53	2	IPR018303
Domain	P_typ_ATPase	ATP8B4 ATP11B	4.68e-03	36	53	2	IPR001757
Domain	ATPASE_E1_E2	ATP8B4 ATP11B	4.68e-03	36	53	2	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP8B4 ATP11B	4.94e-03	37	53	2	IPR008250
Domain	E1-E2_ATPase	ATP8B4 ATP11B	4.94e-03	37	53	2	PF00122
Domain	Olfact_rcpt	OR1S1 OR1L6 OR5K2 OR8B12 OR52W1	5.04e-03	393	53	5	IPR000725
Domain	MFS_dom	SLC43A1 MFSD10 SLC2A3	6.51e-03	134	53	3	IPR020846
Domain	TF_fork_head_CS_2	FOXE1 FOXL1	7.55e-03	46	53	2	IPR030456
Domain	TF_fork_head_CS_1	FOXE1 FOXL1	7.87e-03	47	53	2	IPR018122
Domain	FORK_HEAD_3	FOXE1 FOXL1	8.53e-03	49	53	2	PS50039
Domain	FH	FOXE1 FOXL1	8.53e-03	49	53	2	SM00339
Domain	FORK_HEAD_1	FOXE1 FOXL1	8.53e-03	49	53	2	PS00657
Domain	FORK_HEAD_2	FOXE1 FOXL1	8.53e-03	49	53	2	PS00658
Domain	Forkhead	FOXE1 FOXL1	8.53e-03	49	53	2	PF00250
Domain	Fork_head_dom	FOXE1 FOXL1	8.53e-03	49	53	2	IPR001766
Domain	-	ATP8B4 ATP11B	1.42e-02	64	53	2	3.40.50.1000
Pathway	REACTOME_SODIUM_PROTON_EXCHANGERS	SLC9A4 SLC9A2 SLC9A3 SLC9A6	5.60e-09	9	38	4	M27337
Pathway	REACTOME_SODIUM_PROTON_EXCHANGERS	SLC9A4 SLC9A2 SLC9A3 SLC9A6	5.60e-09	9	38	4	MM15079
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ESYT3 SLC9A4 SLC9A2 SLC9A3 ATP8B4 ATP11B ABCA5 SLC26A7 SLC43A1 TCIRG1 SLC9A6 SLC2A3	1.25e-07	681	38	12	MM14985
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ESYT3 SLC9A4 SLC9A2 SLC9A3 ATP8B4 ATP11B ABCA5 SLC26A7 SLC43A1 TCIRG1 SLC9A6 SLC2A3	2.89e-07	736	38	12	M27287
Pathway	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	SLC9A4 SLC9A2 SLC9A3 SLC26A7 SLC43A1 SLC9A6	3.98e-07	108	38	6	M823
Pathway	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	SLC9A4 SLC9A2 SLC9A3 SLC26A7 SLC43A1 SLC9A6	4.20e-07	109	38	6	MM15074
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC9A4 SLC9A2 SLC9A3 SLC26A7 SLC43A1 SLC9A6 SLC2A3	2.89e-06	238	38	7	MM15076
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC9A4 SLC9A2 SLC9A3 SLC26A7 SLC43A1 SLC9A6 SLC2A3	3.90e-06	249	38	7	M5988
Pathway	WP_ELONGATION_OF_VERY_LONG_CHAIN_FATTY_ACIDS	FADS1 FADS2 ELOVL7	3.91e-06	12	38	3	MM17077
Pathway	KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS	FADS1 TECR FADS2	2.69e-05	22	38	3	M11673
Pathway	WP_SEBALEIC_ACID_FORMATION_AND_METABOLISM	FADS1 FADS2	7.04e-05	5	38	2	M48057
Pathway	WP_LINOLEIC_ACID_METABOLISM_AFFECTED_BY_SARSCOV2	FADS1 FADS2	1.05e-04	6	38	2	M42575
Pathway	WP_METABOLISM_OF_ALPHALINOLENIC_ACID	FADS1 FADS2	1.05e-04	6	38	2	M39844
Pathway	REACTOME_LINOLEIC_ACID_LA_METABOLISM	FADS1 FADS2	1.96e-04	8	38	2	MM14822
Pathway	REACTOME_LINOLEIC_ACID_LA_METABOLISM	FADS1 FADS2	1.96e-04	8	38	2	M27115
Pathway	REACTOME_ALPHA_LINOLENIC_OMEGA3_AND_LINOLEIC_OMEGA6_ACID_METABOLISM	FADS1 FADS2	5.42e-04	13	38	2	MM14821
Pathway	REACTOME_ALPHA_LINOLENIC_OMEGA3_AND_LINOLEIC_OMEGA6_ACID_METABOLISM	FADS1 FADS2	5.42e-04	13	38	2	M27114
Pathway	WP_OMEGA9_FATTY_ACID_SYNTHESIS	FADS1 FADS2	6.31e-04	14	38	2	MM15840
Pathway	WP_OMEGA9_FATTY_ACID_SYNTHESIS	FADS1 FADS2	6.31e-04	14	38	2	M39780
Pathway	WP_OMEGA3_OMEGA6_FATTY_ACID_SYNTHESIS	FADS1 FADS2	7.27e-04	15	38	2	M39789
Pathway	WP_OMEGA3_OMEGA6_FATTY_ACID_SYNTHESIS	FADS1 FADS2	8.29e-04	16	38	2	MM15813
Pathway	REACTOME_FATTY_ACID_METABOLISM	FADS1 TECR FADS2 ELOVL7	1.09e-03	170	38	4	MM15573
Pathway	REACTOME_FATTY_ACID_METABOLISM	FADS1 TECR FADS2 ELOVL7	1.24e-03	176	38	4	M27854
Pathway	REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS	TECR ELOVL7	1.58e-03	22	38	2	MM15451
Pathway	WP_SELENIUM_MICRONUTRIENT_NETWORK	FADS1 FADS2	1.73e-03	23	38	2	MM15979
Pathway	WP_OXYLIPINS_PATHWAYS	FADS1 FADS2	1.88e-03	24	38	2	MM17249
Pathway	REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS	TECR ELOVL7	1.88e-03	24	38	2	M1016
Pathway	REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS	TECR ELOVL7	3.33e-03	32	38	2	MM15446
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR1S1 OR1L6 OR5K2 OR8B12 OR52W1	3.70e-03	389	38	5	M14091
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31C1 SPATA31A5	4.47e-14	6	54	5	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31C1 SPATA31A5	4.47e-14	6	54	5	25930072
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A1 SPATA31A3 SPATA31A7 SPATA31C1 SPATA31A5	3.10e-10	24	54	5	32212159
Pubmed	cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family.	FADS1 FADS3 FADS2	3.54e-09	3	54	3	10860662
Pubmed	Placental expression of Fatty Acid Desaturases 1, 2 and 3 in selected pregnancy pathologies.	FADS1 FADS3 FADS2	3.54e-09	3	54	3	36652541
Pubmed	Association of polyunsaturated fatty acids in breast milk with fatty acid desaturase gene polymorphisms among Chinese lactating mothers.	FADS1 FADS3 FADS2	3.54e-09	3	54	3	27269715
Pubmed	Umbilical cord PUFA are determined by maternal and child fatty acid desaturase (FADS) genetic variants in the Avon Longitudinal Study of Parents and Children (ALSPAC).	FADS1 FADS3 FADS2	3.54e-09	3	54	3	22877655
Pubmed	FADS gene polymorphisms in Koreans: association with ω6 polyunsaturated fatty acids in serum phospholipids, lipid peroxides, and coronary artery disease.	FADS1 FADS3 FADS2	3.54e-09	3	54	3	21040914
Pubmed	Genetic variants in desaturase gene, erythrocyte fatty acids, and risk for type 2 diabetes in Chinese Hans.	FADS1 FADS3 FADS2	3.54e-09	3	54	3	24985009
Pubmed	NHE1, NHE2, and NHE3 contribute to regulation of intracellular pH in murine duodenal epithelial cells.	SLC9A4 SLC9A2 SLC9A3	1.41e-08	4	54	3	10666043
Pubmed	Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study.	FADS1 FADS3 FADS2	1.41e-08	4	54	3	19148276
Pubmed	FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population.	FADS1 FADS3 FADS2	1.41e-08	4	54	3	20562440
Pubmed	Na(+)-dependent transporters mediate HCO(3)(-) salvage across the luminal membrane of the main pancreatic duct.	SLC9A4 SLC9A2 SLC9A3	1.41e-08	4	54	3	10841524
Pubmed	Contributions of Na+/H+ exchanger isoforms to preimplantation development of the mouse.	SLC9A4 SLC9A2 SLC9A3	1.41e-08	4	54	3	9590530
Pubmed	Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef.	SLC9A4 SLC9A2 SLC9A3 SLC9A6	1.56e-08	18	54	4	24874739
Pubmed	Lessons from genetically engineered animal models VIII. Absorption and secretion of ions in the gastrointestinal tract.	SLC9A4 SLC9A2 SLC9A3	7.05e-08	6	54	3	10666041
Pubmed	Molecular transport machinery involved in orchestrating luminal acid-induced duodenal bicarbonate secretion in vivo.	SLC9A2 SLC9A3 KCNQ1	7.05e-08	6	54	3	24018950
Pubmed	NHE1 is the sodium-hydrogen exchanger active in acute intracellular pH regulation in preimplantation mouse embryos.	SLC9A4 SLC9A2 SLC9A3	1.23e-07	7	54	3	23677982
Pubmed	Calcineurin homologous protein isoform 2 (CHP2), Na+/H+ exchangers-binding protein, is expressed in intestinal epithelium.	SLC9A4 SLC9A2 SLC9A3	1.23e-07	7	54	3	12576672
Pubmed	Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population.	FADS1 FADS3 FADS2	2.95e-07	9	54	3	25194280
Pubmed	Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue.	FADS1 FADS2 SLC2A3 ELOVL7	4.55e-07	40	54	4	27760309
Pubmed	Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy.	FADS3 HS2ST1 FADS2 GOLT1B MFSD10	6.71e-07	106	54	5	33087821
Pubmed	Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.	FADS1 FADS3 FADS2	1.27e-06	14	54	3	23378610
Pubmed	Mouse chromosomal location of four Na/H exchanger isoform genes.	SLC9A4 SLC9A2 SLC9A3	1.27e-06	14	54	3	8824815
Pubmed	NHE2-mediated bicarbonate reabsorption in the distal tubule of NHE3 null mice.	SLC9A2 SLC9A3	2.37e-06	2	54	2	15604231
Pubmed	FADS1-FADS2 genetic polymorphisms are associated with fatty acid metabolism through changes in DNA methylation and gene expression.	FADS1 FADS2	2.37e-06	2	54	2	30157936
Pubmed	Impact of FADS genotype on polyunsaturated fatty acid content in human milk extracellular vesicles: A genetic association study.	FADS1 FADS2	2.37e-06	2	54	2	38566550
Pubmed	Loss of the NHE2 Na(+)/H(+) exchanger has no apparent effect on diarrheal state of NHE3-deficient mice.	SLC9A2 SLC9A3	2.37e-06	2	54	2	11705743
Pubmed	A novel FADS1 isoform potentiates FADS2-mediated production of eicosanoid precursor fatty acids.	FADS1 FADS2	2.37e-06	2	54	2	22619218
Pubmed	Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids.	FADS1 FADS2	2.37e-06	2	54	2	16670158
Pubmed	Limited Evidence for Selection at the FADS Locus in Native American Populations.	FADS1 FADS2	2.37e-06	2	54	2	32145021
Pubmed	Dietary n-3 and n-6 polyunsaturated fatty acids, the FADS gene, and the risk of gastric cancer in a Korean population.	FADS1 FADS2	2.37e-06	2	54	2	29491470
Pubmed	FADS1 FADS2 gene cluster, PUFA intake and blood lipids in children: results from the GINIplus and LISAplus studies.	FADS1 FADS2	2.37e-06	2	54	2	22629455
Pubmed	A single nucleotide polymorphism in the FADS1/FADS2 gene is associated with plasma lipid profiles in two genetically similar Asian ethnic groups with distinctive differences in lifestyle.	FADS1 FADS2	2.37e-06	2	54	2	20364269
Pubmed	Polymorphisms in FADS1 and FADS2 alter plasma fatty acids and desaturase levels in type 2 diabetic patients with coronary artery disease.	FADS1 FADS2	2.37e-06	2	54	2	27004414
Pubmed	FADS Polymorphism, Omega-3 Fatty Acids and Diabetes Risk: A Systematic Review.	FADS1 FADS2	2.37e-06	2	54	2	29899246
Pubmed	Dietary pattern regulates fatty acid desaturase 1 gene expression in Indian pregnant women to spare overall long chain polyunsaturated fatty acids levels.	FADS1 FADS2	2.37e-06	2	54	2	30511301
Pubmed	Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism.	FADS1 FADS2	2.37e-06	2	54	2	19809313
Pubmed	Variants of the FADS1 FADS2 gene cluster, blood levels of polyunsaturated fatty acids and eczema in children within the first 2 years of life.	FADS1 FADS2	2.37e-06	2	54	2	20948998
Pubmed	Relationship between a common variant in the fatty acid desaturase (FADS) cluster and eicosanoid generation in humans.	FADS1 FADS2	2.37e-06	2	54	2	24962583
Pubmed	Maternal polymorphisms in the FADS1 and FADS2 genes modify the association between PUFA ingestion and plasma concentrations of omega-3 polyunsaturated fatty acids.	FADS1 FADS2	2.37e-06	2	54	2	31568926
Pubmed	Do FADS genotypes enhance our knowledge about fatty acid related phenotypes?	FADS1 FADS2	2.37e-06	2	54	2	19948371
Pubmed	The role of fatty acid desaturase (FADS) genes in oleic acid metabolism: FADS1 Δ7 desaturates 11-20:1 to 7,11-20:2.	FADS1 FADS2	2.37e-06	2	54	2	29413358
Pubmed	Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis.	FADS1 FADS2	2.37e-06	2	54	2	32186652
Pubmed	Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion.	SLC9A2 SLC9A3	2.37e-06	2	54	2	9502765
Pubmed	Insertion-deletions in a FADS2 intron 1 conserved regulatory locus control expression of fatty acid desaturases 1 and 2 and modulate response to simvastatin.	FADS1 FADS2	2.37e-06	2	54	2	22748975
Pubmed	Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition.	FADS1 FADS2	2.37e-06	2	54	2	23221573
Pubmed	Association of the FADS gene cluster with coronary artery disease and plasma lipid concentrations in the northern Chinese Han population.	FADS3 FADS2	2.37e-06	2	54	2	28237083
Pubmed	Long-chain polyunsaturated fatty acid status in obesity: a systematic review and meta-analysis.	FADS1 FADS2	2.37e-06	2	54	2	25828602
Pubmed	FADS gene variants modulate the effect of dietary fatty acid intake on allergic diseases in children.	FADS1 FADS2	2.37e-06	2	54	2	21793953
Pubmed	Genetic variation at the FADS1-FADS2 gene locus influences delta-5 desaturase activity and LC-PUFA proportions after fish oil supplement.	FADS1 FADS2	2.37e-06	2	54	2	23160180
Pubmed	Genetic variation in FADS genes is associated with maternal long-chain PUFA status but not with cognitive development of infants in a high fish-eating observational study.	FADS1 FADS2	2.37e-06	2	54	2	26474818
Pubmed	Genetic variation of the FADS1 FADS2 gene cluster and n-6 PUFA composition in erythrocyte membranes in the European Prospective Investigation into Cancer and Nutrition-Potsdam study.	FADS1 FADS2	2.37e-06	2	54	2	20691134
Pubmed	Erythrocyte membrane phospholipid fatty acids, desaturase activity, and dietary fatty acids in relation to risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study.	FADS1 FADS2	2.37e-06	2	54	2	20980488
Pubmed	Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome.	FADS1 FADS2	2.37e-06	2	54	2	21733300
Pubmed	FADS2 polymorphisms are associated with plasma arachidonic acid and estimated desaturase-5 activity in a cross-sectional study.	FADS1 FADS2	2.37e-06	2	54	2	33011673
Pubmed	Intestinal NaCl transport in NHE2 and NHE3 knockout mice.	SLC9A2 SLC9A3	2.37e-06	2	54	2	11960774
Pubmed	Increasing dietary EPA and DHA influence estimated fatty acid desaturase activity in systemic organs which is reflected in the red blood cell in mice.	FADS1 FADS2	2.37e-06	2	54	2	28697636
Pubmed	Dietary n-3 and n-6 polyunsaturated fatty acid intake interacts with FADS1 genetic variation to affect total and HDL-cholesterol concentrations in the Doetinchem Cohort Study.	FADS1 FADS2	2.37e-06	2	54	2	20484448
Pubmed	Decreased liver fatty acid delta-6 and delta-5 desaturase activity in obese patients.	FADS1 FADS2	2.37e-06	2	54	2	19875987
Pubmed	FADS1 and FADS2 polymorphism are associated with changes in fatty acid concentrations after calorie-restricted Central European and Mediterranean diets.	FADS1 FADS2	2.37e-06	2	54	2	31567872
Pubmed	Carrying minor allele of FADS1 and haplotype of FADS1 and FADS2 increased the risk of metabolic syndrome and moderate but not low fat diets lowered the risk in two Korean cohorts.	FADS1 FADS2	2.37e-06	2	54	2	29779171
Pubmed	Genetic variants of the fatty acid desaturase gene cluster predict amounts of red blood cell docosahexaenoic and other polyunsaturated fatty acids in pregnant women: findings from the Avon Longitudinal Study of Parents and Children.	FADS1 FADS2	2.37e-06	2	54	2	21106917
Pubmed	Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 ( FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes.	FADS1 FADS2	2.37e-06	2	54	2	18479586
Pubmed	Adiposity Associated Plasma Linoleic Acid is Related to Demographic, Metabolic Health and Haplotypes of FADS1/2 Genes in Irish Adults.	FADS1 FADS2	2.37e-06	2	54	2	29388724
Pubmed	FADS1/2 control lipid metabolism and ferroptosis susceptibility in triple-negative breast cancer.	FADS1 FADS2	2.37e-06	2	54	2	38926633
Pubmed	Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2.	SLC9A2 SLC9A3	2.37e-06	2	54	2	11553519
Pubmed	Differences in erythrocyte phospholipid membrane long-chain polyunsaturated fatty acids and the prevalence of fatty acid desaturase genotype among African Americans and European Americans.	FADS1 FADS2	2.37e-06	2	54	2	33310680
Pubmed	Mendelian randomization shows sex-specific associations between long-chain PUFA-related genotypes and cognitive performance in Danish schoolchildren.	FADS1 FADS2	2.37e-06	2	54	2	28515069
Pubmed	Erythrocyte polyunsaturated fatty acid composition is associated with depression and FADS genotype in Caucasians.	FADS1 FADS2	2.37e-06	2	54	2	28552045
Pubmed	Association of fatty acid desaturase genes with attention-deficit/hyperactivity disorder.	FADS1 FADS2	2.37e-06	2	54	2	16893529
Pubmed	Genetic variants of the FADS1 FADS2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation.	FADS1 FADS2	2.37e-06	2	54	2	18936223
Pubmed	Docosahexaenoic acid (DHA) supplementation in pregnancy differentially modulates arachidonic acid and DHA status across FADS genotypes in pregnancy.	FADS1 FADS2	2.37e-06	2	54	2	25500337
Pubmed	Novel amiloride-sensitive sodium-dependent proton secretion in the mouse proximal convoluted tubule.	SLC9A2 SLC9A3	2.37e-06	2	54	2	10772659
Pubmed	FADS Gene Polymorphisms, Fatty Acid Desaturase Activities, and HDL-C in Type 2 Diabetes.	FADS1 FADS2	2.37e-06	2	54	2	28555039
Pubmed	Intestinal brush-border Na+/H+ exchanger-3 drives H+-coupled iron absorption in the mouse.	SLC9A2 SLC9A3	2.37e-06	2	54	2	27390324
Pubmed	Influence of FADS polymorphisms on tracking of serum glycerophospholipid fatty acid concentrations and percentage composition in children.	FADS1 FADS2	2.37e-06	2	54	2	21818279
Pubmed	Vitamin B-6 restriction impairs fatty acid synthesis in cultured human hepatoma (HepG2) cells.	FADS1 FADS2	2.37e-06	2	54	2	23211517
Pubmed	Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios.	FADS1 FADS2	2.37e-06	2	54	2	20427696
Pubmed	Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster.	FADS1 FADS2	2.37e-06	2	54	2	28957329
Pubmed	Associations of umbilical cord fatty acid profiles and desaturase enzyme indices with birth weight for gestational age in Japanese infants.	FADS1 FADS2	2.37e-06	2	54	2	33387849
Pubmed	FADS gene cluster polymorphisms: important modulators of fatty acid levels and their impact on atopic diseases.	FADS1 FADS2	2.37e-06	2	54	2	19776639
Pubmed	Polyunsaturated fatty acid regulation of adipocyte FADS1 and FADS2 expression and function.	FADS1 FADS2	2.37e-06	2	54	2	25755223
Pubmed	The role of FADS1/2 polymorphisms on cardiometabolic markers and fatty acid profiles in young adults consuming fish oil supplements.	FADS1 FADS2	2.37e-06	2	54	2	24936800
Pubmed	Early nutrition in combination with polymorphisms in fatty acid desaturase gene cluster modulate fatty acid composition of cheek cells' glycerophospholipids in school-age children.	FADS1 FADS2	2.37e-06	2	54	2	31638497
Pubmed	Intestinal distribution of human Na+/H+ exchanger isoforms NHE-1, NHE-2, and NHE-3 mRNA.	SLC9A2 SLC9A3	2.37e-06	2	54	2	8843774
Pubmed	Interaction of fatty acid genotype and diet on changes in colonic fatty acids in a Mediterranean diet intervention study.	FADS1 FADS2	2.37e-06	2	54	2	24022589
Pubmed	FADS1-FADS2 gene cluster confers risk to polycystic ovary syndrome.	FADS1 FADS2	2.37e-06	2	54	2	26879377
Pubmed	Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus.	FADS1 FADS2	2.37e-06	2	54	2	36864135
Pubmed	Lack of association of SNPs from the FADS1-FADS2 gene cluster with major depression or suicidal behavior.	FADS1 FADS2	2.37e-06	2	54	2	26513616
Pubmed	FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk.	FADS1 FADS2	2.37e-06	2	54	2	20335541
Pubmed	Association of two polymorphisms in the FADS1/FADS2 gene cluster and the risk of coronary artery disease and ischemic stroke.	FADS1 FADS2	2.37e-06	2	54	2	26261632
Pubmed	Delta-5 and delta-6 desaturases: crucial enzymes in polyunsaturated fatty acid-related pathways with pleiotropic influences in health and disease.	FADS1 FADS2	2.37e-06	2	54	2	25038994
Pubmed	FADS1 and FADS2 Gene Polymorphisms Modulate the Relationship of Omega-3 and Omega-6 Fatty Acid Plasma Concentrations in Gestational Weight Gain: A NISAMI Cohort Study.	FADS1 FADS2	2.37e-06	2	54	2	35268031
Pubmed	HCO3- salvage mechanisms in the submandibular gland acinar and duct cells.	SLC9A2 SLC9A3	2.37e-06	2	54	2	11139574
Pubmed	Genetically determined variation in polyunsaturated fatty acid metabolism may result in different dietary requirements.	FADS1 FADS2	2.37e-06	2	54	2	18626191
Pubmed	Role of FADS1 and FADS2 polymorphisms in polyunsaturated fatty acid metabolism.	FADS1 FADS2	2.37e-06	2	54	2	20045144
Pubmed	Polymorphisms in FADS1 and FADS2 alter desaturase activity in young Caucasian and Asian adults.	FADS1 FADS2	2.37e-06	2	54	2	21414826
Pubmed	FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease.	FADS1 FADS2	2.37e-06	2	54	2	18842780
Pubmed	Associations between Fatty Acid Intake and Status, Desaturase Activities, and FADS Gene Polymorphism in Centrally Obese Postmenopausal Polish Women.	FADS1 FADS2	2.37e-06	2	54	2	30103441
Interaction	CHP2 interactions	SLC9A4 SLC9A2 SLC9A3	4.25e-06	14	47	3	int:CHP2
Interaction	PDE2A interactions	FADS3 HS2ST1 FADS2 GOLT1B MFSD10	8.65e-06	120	47	5	int:PDE2A
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	3.79e-05	8	54	2	chr9q12
Cytoband	Ensembl 112 genes in cytogenetic band chr11q12	FADS1 FADS3 OR1S1 SLC43A1 FADS2	5.44e-05	345	54	5	chr11q12
Cytoband	9q22	FOXE1 SPATA31C1	2.29e-04	19	54	2	9q22
Cytoband	9p13.1	SPATA31A1 SPATA31A3	3.69e-04	24	54	2	9p13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr9q22	FOXE1 SPATA31C2 SPATA31C1	1.72e-03	200	54	3	chr9q22
GeneFamily	Fatty acid desaturases	FADS1 FADS3 FADS2	3.38e-07	8	34	3	553
GeneFamily	Solute carriers	SLC9A4 SLC9A2 SLC9A3 SLC26A7 SLC43A1 SLC9A6 SLC2A3	7.28e-06	395	34	7	752
GeneFamily	ATPase phospholipid transporting	ATP8B4 ATP11B	3.55e-04	15	34	2	1210
GeneFamily	Olfactory receptors, family 1	OR1S1 OR1L6	2.56e-03	40	34	2	147
GeneFamily	Forkhead boxes	FOXE1 FOXL1	2.95e-03	43	34	2	508
GeneFamily	G protein-coupled receptors, Class A orphans	GPR68 GPR171	9.43e-03	78	34	2	262
Coexpression	BENPORATH_EED_TARGETS	FOXE1 GPM6B ESYT3 SLC9A2 SLC9A3 HTR1B KCNQ1 PIP5K1B FOXL1 CDC7	2.62e-05	1059	50	10	M7617
Coexpression	GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_UP	ATP8B4 GPR68 SMCHD1 SLC2A3 NEDD4	3.76e-05	198	50	5	M6178
Coexpression	GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_UP	ATP8B4 GPR68 SMCHD1 SLC2A3 NEDD4	3.76e-05	198	50	5	M6166
Coexpression	GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP	GPR68 TECR FADS2 SLC2A3 NEDD4	3.94e-05	200	50	5	M6242
Coexpression	GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN	SLC9A4 RBPMS SLC43A1 TCIRG1 PIP5K1B	3.94e-05	200	50	5	M6237
Coexpression	HALLMARK_BILE_ACID_METABOLISM	FADS1 ABCA5 FADS2 NEDD4	6.25e-05	112	50	4	M5948
Coexpression	DURANTE_ADULT_OLFACTORY_NEUROEPITHELIUM_OLFACTORY_ENSHEATHING_GLIA	GPM6B FADS1 FADS3 FADS2	6.93e-05	115	50	4	M39290
CoexpressionAtlas	NK cells, NK.MCMV7.Sp, CD3-,NK1.1+, Spleen, avg-3	ATP8B4 RBPMS ARSB ATP11B GPR68 GPR171 SLC2A3 ELOVL7	2.99e-06	411	47	8	GSM538312_500
CoexpressionAtlas	alpha beta T cells, preT.ETP.Th, Lin-/lo CD25- CD44+ cKit+, Thymus, avg-3	ATP8B4 FADS1 FADS3 SLC43A1 FADS2 PIP5K1B GPR171 NEDD4	3.21e-06	415	47	8	GSM854335_500
CoexpressionAtlas	alpha beta T cells, preT.ETP-2A.Th, Lin-/lo CD25int CD44+ cKit+, Thymus, avg-2	ATP8B4 FADS1 FADS3 SLC43A1 FADS2 PIP5K1B GPR171 NEDD4	3.89e-06	426	47	8	GSM791152_500
CoexpressionAtlas	NK cells, NK.49CI-.Sp, NK1.1+ CD3- Ly49C/I-, Spleen, avg-3	ATP8B4 RBPMS ARSB ATP11B GPR171 ELOVL7	1.63e-04	372	47	6	GSM538288_500
CoexpressionAtlas	alpha beta T cells, T.8Eff.Sp.OT1.d8.LisOva, CD8+ CD45.1+, Spleen, avg-3	ATP8B4 ARSB ATP11B GPR68 SLC2A3 ELOVL7	1.82e-04	380	47	6	GSM605901_500
CoexpressionAtlas	NK cells, NK.b2m-.Sp, NK1.1+ TCRb-, Spleen, avg-3	ATP8B4 RBPMS ARSB ATP11B GPR171 ELOVL7	2.10e-04	390	47	6	GSM538291_500
CoexpressionAtlas	NK cells, NK.DAP12-.Sp, NK1.1+ CD3-, Spleen, avg-3	ATP8B4 RBPMS ARSB ATP11B GPR68 ELOVL7	2.47e-04	402	47	6	GSM538297_500
CoexpressionAtlas	B cells, proB.CLP.BM, CD19- IgM- CD43+ CD24- AA4.1+ CD45R- CD117+ IL7R+, Bone marrow, avg-1	ATP8B4 FADS3 FADS2 PIP5K1B GPR171 SLC2A3	2.57e-04	405	47	6	GSM538343_500
CoexpressionAtlas	Stem Cells, SC.LTSL.BM, CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-1	RBPMS FADS1 SLC43A1 FADS2 PIP5K1B NEDD4	2.71e-04	409	47	6	GSM476663_500
CoexpressionAtlas	alpha beta T cells, preT.DN2A.Th, Lin-/lo CD25hi CD44+ cKithi, Thymus, avg-2	ATP8B4 FADS1 SLC43A1 FADS2 PIP5K1B GPR171	2.71e-04	409	47	6	GSM791139_500
CoexpressionAtlas	Plasmacytoid, DC.pDC.8+.Sp, GR1-PE CD11c-eFluor750 CD8-eFluor480 CD45-APC B220, Spleen, avg-3	GPM6B FADS3 ABCA5 FADS2 TCIRG1 SLC2A3	2.71e-04	409	47	6	GSM605840_500
CoexpressionAtlas	Fetal Liver, SC.STSL.FL, IgM- CD24- CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Fetal Liver, avg-2	RBPMS FADS1 SLC43A1 FADS2 CDC7 NEDD4	2.75e-04	410	47	6	GSM791122_500
CoexpressionAtlas	Plasmacytoid, DC.pDC.8-.Sp, GR1-PE CD11c-eFluor750 CD8-eFluor480 CD45-APC B220, Spleen, avg-3	GPM6B FADS3 ABCA5 FADS2 TCIRG1 SLC2A3	2.82e-04	412	47	6	GSM605843_500
CoexpressionAtlas	NK cells, NK.H+.MCMV7.Sp, NK1.1+ TCRb- Ly49H+, Spleen, avg-3	ATP8B4 RBPMS ARSB GPR68 GPR171 ELOVL7	2.86e-04	413	47	6	GSM538303_500
CoexpressionAtlas	NK cells, NK.49H-.Sp, NK1.1+, Spleen, avg-3	RBPMS ARSB GPR68 GPR171 SLC2A3 ELOVL7	2.86e-04	413	47	6	GSM605817_500
CoexpressionAtlas	Stem Cells, SC.LTSL.BM, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-2	RBPMS FADS1 SLC43A1 FADS2 PIP5K1B NEDD4	3.20e-04	422	47	6	GSM399442_500
CoexpressionAtlas	Stem Cells, SC.STSL.BM, CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Bone marrow, avg-3	RBPMS FADS1 SLC43A1 FADS2 PIP5K1B NEDD4	3.25e-04	423	47	6	GSM399454_500
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6B FADS3 FADS2 KCNQ1 PAQR6 ELOVL7	9.46e-08	184	54	6	10706441e7695212f95689414f31e8082b5eaf0a
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6B FADS3 FADS2 KCNQ1 PAQR6 ELOVL7	9.46e-08	184	54	6	4bb0976a75126ad2b3deb5d2229f0716fafe200e
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPM6B FADS3 ABCA5 FADS2 GPR171	2.15e-06	173	54	5	4f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPM6B FADS3 ABCA5 FADS2 GPR171	2.15e-06	173	54	5	9bbea566964281f47bf75d665b7d69ba8326e207
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A4 ATP8B4 ARSB GPR68 GPR171	2.41e-06	177	54	5	3cb96d7d56c9ff90f1f8a6caaf49e580e2524c7d
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 ARSB GPR68 GPR171	3.13e-05	148	54	4	3aa47398cb805c6c6e16b375cc3e9c7f04bb91f4
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 ARSB GPR68 GPR171	3.30e-05	150	54	4	c18d3f66b384ec9ee0b8fb6a369b9a524b5dcaeb
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 ARSB GPR68 GPR171	3.47e-05	152	54	4	ed6df77ba04b715e12c2e1591b4a1e894ca49d25
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATP8B4 GPR68 SPATA31A7 TRMT12	3.56e-05	153	54	4	4eb9c2d7e4b95d44198fc87dc115a08ef0153e26
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATP8B4 GPR68 SPATA31A7 TRMT12	3.56e-05	153	54	4	26b5b45c117d155b028d298a0b93e16d343dca97
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ESYT3 SLC9A2 SLC26A7 FOXL1	3.56e-05	153	54	4	151c469b26f9adf04dd6f117f03bef760cc3d45d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATP8B4 GPR68 SPATA31A7 TRMT12	3.56e-05	153	54	4	0f12e38f2cbf69a520764289b0aa4dedc645f714
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 ARSB GPR68 GPR171	4.04e-05	158	54	4	5d926be5a0ebe8257cd552afa7844171f9ff01c0
ToppCell	CV-Mild-4\|CV / Virus stimulation, Condition and Cluster	GPM6B FADS2 PIP5K1B SLC2A3	4.24e-05	160	54	4	be89efeeecb0de96ce136a7a62738f15dc0badb2
ToppCell	BL-critical-LOC-Myeloid-Basophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FADS1 FADS3 ARSB LMBRD2	4.45e-05	162	54	4	25ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXE1 SLC9A3 SLC26A7 ELOVL7	4.67e-05	164	54	4	cdb8cd2d6b369189ea77e4946738e2816d502e03
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXE1 SLC9A3 SLC26A7 ELOVL7	4.67e-05	164	54	4	5dbfcdd450f652b16d97da53b528d4584b0eabcf
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXE1 SLC9A3 SLC26A7 ELOVL7	4.67e-05	164	54	4	f1423f4434af4af9c60c8a5b0b0abec4a7df9401
ToppCell	droplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6B FADS3 GPR171 SLC2A3	5.13e-05	168	54	4	e8878ec68b21c8d5694d7209b816d2f869673164
ToppCell	droplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6B FADS3 GPR171 SLC2A3	5.13e-05	168	54	4	a007758c219d3d5db2b5529f29af63be0d408304
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS2 KCNQ1 PAQR6 ELOVL7	5.13e-05	168	54	4	100ab6d36592b61f4db9f8cb90c48afac016d679
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 ARSB GPR68 GPR171	5.37e-05	170	54	4	da4dde7d0491ccc298cec7474a6a76ff3db36a4c
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 ARSB GPR171 SLC2A3	5.49e-05	171	54	4	846a9acfff0bf0a9baf65dc07b7d7a9217ed6598
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 KCNQ1 PAQR6 ELOVL7	6.01e-05	175	54	4	8902c38067f025b094ca9c28c449c32a66eded1c
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 KCNQ1 PAQR6 ELOVL7	6.01e-05	175	54	4	6bb8fc2959583644f16b22e906af91af62a3a633
ToppCell	Control-Lymphoid-pDC\|Control / Condition, Lineage and Cell class	GPM6B RBPMS FADS1 FADS2	6.14e-05	176	54	4	5de16ff65476bde8b23322a44e11412e14f1bafe
ToppCell	droplet-Pancreas-Exocrine-24m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6B FADS3 KCNQ1 PAQR6	6.28e-05	177	54	4	a5b54792ef948a1e1de66301a60e051250189f59
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATP8B4 ARSB GPR68 GPR171	6.56e-05	179	54	4	b7a2429d07d7146b32b3552a5f2a2542105a71e0
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6B FADS3 FADS2 GPR171	6.85e-05	181	54	4	fb64da1dde37fe6ba7de2586cd58848ac1974f24
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A2 FADS3 FADS2 GPR171	7.00e-05	182	54	4	33afbb7c4352b03266501b1f4f0e751c12c7350d
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 FADS2 KCNQ1 PAQR6	7.30e-05	184	54	4	978135173891c83470370a42b2801e09eb740320
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 FADS2 KCNQ1 PAQR6	7.30e-05	184	54	4	f58922cf593f4b739f2713ef88a2ca3014f927e9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A4 SLC9A2 SLC26A7 KCNQ1	7.45e-05	185	54	4	3d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A4 SLC9A2 RBPMS KCNQ1	7.45e-05	185	54	4	a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell	droplet-Bladder-Unstain-18m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNQ1 PIP5K1B SLC2A3 CDC7	7.61e-05	186	54	4	e3a14f3ccadbf3211822c67b8956ee01f563307a
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FADS3 ABCA5 FADS2 ELOVL7	7.61e-05	186	54	4	ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FADS3 ABCA5 FADS2 ELOVL7	7.61e-05	186	54	4	ed924852cd7132c8f6703522037dc22bd2c83193
ToppCell	droplet-Skin-nan-21m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B4 FADS3 GPR68 GPR171	7.77e-05	187	54	4	ea33a5bd60b7f5f6d5b07a7f06a5a56395943641
ToppCell	droplet-Skin-nan-21m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B4 FADS3 GPR68 GPR171	7.77e-05	187	54	4	38d7b19fde6811f5fbf548b2464486b197476dc6
ToppCell	droplet-Skin-nan-21m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B4 FADS3 GPR68 GPR171	7.77e-05	187	54	4	1dbc2c0ab85033e5de776bbfdb73ebd3a50d2cc6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A4 SLC9A2 SLC26A7 KCNQ1	8.10e-05	189	54	4	a9864873b19ab3e60acf11f288fa7275badc2e42
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A4 SLC9A2 RBPMS KCNQ1	8.26e-05	190	54	4	11d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-intestinal_crypt_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS1 FADS2 KCNQ1 MFSD10	8.26e-05	190	54	4	933c778bb8ec89621906fe7d484c1d2c6cd28d80
ToppCell	facs-Marrow-KLS-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBPMS FADS1 FADS2 NEDD4	8.26e-05	190	54	4	11f32f46661e44770782b8ec13c00028e1dfc3cd
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A4 SLC9A2 SLC26A7 KCNQ1	8.26e-05	190	54	4	b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPM6B SLC9A4 SLC9A2 RBPMS	8.26e-05	190	54	4	b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCell	facs-Marrow-KLS-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBPMS FADS1 FADS2 NEDD4	8.26e-05	190	54	4	20f4f6fe09345878484086047061d6f900f9d476
ToppCell	facs-GAT\|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6B RBPMS FADS3 FADS2	8.43e-05	191	54	4	1f5d1e8c313a8dc83c06d2ee45f369b0ec507fbf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A4 SLC9A2 RBPMS KCNQ1	8.43e-05	191	54	4	96b78b4e819ea6052334bfcbc7abbf35897df885
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ESYT3 FADS1 FADS2 PIP5K1B	9.13e-05	195	54	4	d9694db6bf239636d1335016878c98f6ee2eb0eb
ToppCell	3'-Adult-LargeIntestine-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPM6B FADS3 FADS2 PAQR6	9.69e-05	198	54	4	991db02a76f7506848827601e927cf997cb520d3
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPM6B FADS2 PAQR6 RIC3	9.69e-05	198	54	4	6e314dc820db9c53fe7fc7c96bed4d7d9a325160
ToppCell	3'-Adult-LargeIntestine-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPM6B FADS3 FADS2 PAQR6	9.69e-05	198	54	4	2488ea95003f218afb25ecc873805b825e6cc409
ToppCell	3'-Adult-LargeIntestine-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPM6B FADS3 FADS2 PAQR6	9.69e-05	198	54	4	98ab27335d126fa7817a46953948e524d91248f8
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ESYT3 FADS1 FADS2 PIP5K1B	9.88e-05	199	54	4	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	MS-IIF-Lymphocyte-T/NK-NK_CD56bright\|IIF / Disease, condition lineage and cell class	ATP8B4 GPR68 TCIRG1 PAQR6	9.88e-05	199	54	4	9eb2b7d4900b118338590db778a47504559e228d
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPM6B FADS2 PAQR6 RIC3	9.88e-05	199	54	4	a816b0eed80530113b7e720bbd2311a544ed8ed1
ToppCell	Biopsy_Control_(H.)-Epithelial-MUC5AC+_High\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	FOXE1 SLC9A4 SLC9A3 UGT1A6	9.88e-05	199	54	4	a5240868cea40574ed4ee45eb27a00c1812957ed
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp-Endothelial_Tip.Dcn.Mgp-Penk_(Penk)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SLC26A7 SLC43A1 FOXL1	2.03e-04	94	54	3	8fb9adf0db3b0007204716869d895700cbdc6231
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp-Endothelial_Tip.Dcn.Mgp-Clu_(Clu)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ESYT3 SLC26A7 FOXL1	2.16e-04	96	54	3	9a1da3809073a4321134bf3767e0a40398b69caa
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ESYT3 SLC26A7 FOXL1	4.57e-04	124	54	3	b0ed84522180f8cea541461faf7882c57abf8cd4
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ESYT3 SLC26A7 FOXL1	4.57e-04	124	54	3	231862f849d8ab73c6a44c782d33ef2f07661baf
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	RBPMS PIP5K1B PAQR6	5.86e-04	135	54	3	b444005987093efab3265201b3541d7941816cc2
ToppCell	(09)_Ionocytes\|World / shred by cell type and Timepoint	SLC9A4 KCNQ1 ELOVL7	5.86e-04	135	54	3	237b9b646513ca6e4b754c0da95d24015b3661f7
ToppCell	TCGA-Thryoid\|World / Sample_Type by Project: Shred V9	FOXE1 ESYT3 SLC26A7	6.25e-04	138	54	3	8cbae2ec9a51712bed5b4e5f9f834ecccb6b7a47
ToppCell	droplet-Heart-nan-3m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B4 GPR68 GPR171	6.51e-04	140	54	3	ab90f6f30d89761687f8836e3d327d143ce49ed4
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|Lung / Manually curated celltypes from each tissue	ATP8B4 GPR68 GPR171	6.79e-04	142	54	3	c3db15bcb305ebdf5c9ca0b5c8ce63fab978590b
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 GPR68 GPR171	6.79e-04	142	54	3	efe2418436ad1320b8e8fce38619ac65516ef077
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 GPR68 GPR171	6.93e-04	143	54	3	138033ff447a61a1bc289b21db82151dcc6a4c7e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A4 XKR9 UGT1A6	7.21e-04	145	54	3	bfa196ac1db7acbfcbb2ba9f137036a95e16e091
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-immature_natural_killer_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ATP8B4 GPR68 PAQR6	7.35e-04	146	54	3	40fac8a298152ec7f7eeeed5a2d28541aea3b338
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Serpinf1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC9A4 SLC9A2 PIP5K1B	7.80e-04	149	54	3	5293c50b3fb41b1edaf9a97354899bd13770078c
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SMCHD1 SLC2A3 TRMT12	8.11e-04	151	54	3	b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCell	severe_COVID-19-NK_CD56bright\|World / disease group, cell group and cell class (v2)	ATP8B4 RBPMS GPR68	8.26e-04	152	54	3	ab5a4e47b23d16018642d4c9c7f41b30205edf73
ToppCell	droplet-Lung-nan-3m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESYT3 GPR68 CDC7	8.26e-04	152	54	3	77b319f594d5e4df29034bbf69c7490076f89dd3
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 GPR68 GPR171	8.42e-04	153	54	3	e25ddf75d78edfac962c8ec503c9f70f0f7f25bc
ToppCell	PBMC-Control-cDC_8\|Control / Compartment, Disease Groups and Clusters	ABCA5 SLC43A1 FADS2	8.42e-04	153	54	3	db1a6914f2033fb0748e0523cffe5d6dc4e901be
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A2 ARSB SLC2A3	8.58e-04	154	54	3	75eac6970259a6916fcfa6d3400509cfa2d98d9d
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 GPR68 GPR171	8.74e-04	155	54	3	d8e9f355ce933f6383c3d1e35ff55235a95c7fcd
ToppCell	facs-Marrow-KLS-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA5 GPR68 FADS2	9.07e-04	157	54	3	5d08ff0ba9d3df9cc30f13cab2d2b395ea6f3446
ToppCell	facs-Marrow-KLS-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA5 GPR68 FADS2	9.07e-04	157	54	3	ad9c9b7dfeee3ae46e7e593c51a0407df12195b4
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6B FADS3 GPR171	9.07e-04	157	54	3	fc127e7720649e746f3d3f5c2e9e63784767106a
ToppCell	Leuk-UTI-Lymphocyte-T_NK-NK_CD56bright\|Leuk-UTI / Disease, Lineage and Cell Type	ATP8B4 GPR68 PAQR6	9.07e-04	157	54	3	db0057741d06e212a9543cb4b011659b79efeafc
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6B FADS3 GPR171	9.07e-04	157	54	3	66a191cef4aa00811bb04462310d012610006f85
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A3 RBPMS GPR171	9.41e-04	159	54	3	709b57f992a29878cc899d760d144d36cb5cb280
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic-6\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	HTR1B ARSB FOXL1	9.41e-04	159	54	3	85501c636cd04f15ba1be24df1ba7ac909633ce8
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Lymphocytic-mature_NK_T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B4 GPR68 GPR171	9.41e-04	159	54	3	32d4c9f7ba6a96ce8443396b80568b41cbfc4927
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR68 GPR171 SLC2A3	9.58e-04	160	54	3	939e25ef8b64242da2d28ef8342c8eb9cd199f17
ToppCell	CV-Mild-4\|Mild / Virus stimulation, Condition and Cluster	GPM6B FADS3 SLC2A3	9.58e-04	160	54	3	2e24f8de5086b086863d3bf4d9afbd9bc93f4d5e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 PIP5K1B ELOVL7	9.58e-04	160	54	3	2d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 PIP5K1B ELOVL7	9.58e-04	160	54	3	8bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCell	droplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESYT3 GPR68 CDC7	9.58e-04	160	54	3	8a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCell	PND03-Immune-Immune_Myeloid-DC-cDC1\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARSB GPR68 GPR171	9.76e-04	161	54	3	0e2b54a63781397f6b99eb0e201fbb820cbd7cc6
ToppCell	cellseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-ILC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ATP8B4 GPR68 GPR171	9.93e-04	162	54	3	553f91eaba72bcffb733ede45418bbee39c653ab
ToppCell	Bronchial-10x5prime-Stromal-Schwann\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GPM6B PAQR6 ELOVL7	9.93e-04	162	54	3	afffecc6c504930554aafc12c5bffa53e3c5b016
ToppCell	droplet-Lung-nan-3m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARSB GPR171 ELOVL7	9.93e-04	162	54	3	4b490989005bb03d4e7bbea01580f8548eff150f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A4 SLC9A2 KCNQ1	9.93e-04	162	54	3	285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARSB GPR171 ELOVL7	9.93e-04	162	54	3	e4a09bf1a51710f6c57e6e01edf8b4619459d96d
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Adult / Lineage, Cell type, age group and donor	GPM6B RBPMS PIP5K1B	1.01e-03	163	54	3	e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell	facs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATP8B4 GPR68 GPR171	1.03e-03	164	54	3	5ca7b69684a8bb12dd0b45e7ad94e30d16ed01ce
Disease	nephrolithiasis (implicated_via_orthology)	SLC9A4 SLC9A2 SLC9A3	3.78e-08	5	47	3	DOID:585 (implicated_via_orthology)
Disease	lysophosphatidylethanolamine 18:2 measurement	FADS1 FADS3 FADS2 LMBRD2	8.23e-08	26	47	4	EFO_0010369
Disease	level of Phosphatidylcholine (O-18:2_18:1) in blood serum	FADS1 FADS3 FADS2	1.32e-07	7	47	3	OBA_2045133
Disease	lysophosphatidylcholine 22:4 measurement	FADS1 FADS3 FADS2	1.32e-07	7	47	3	EFO_0021461
Disease	phosphatidylcholine 35:5 measurement	FADS1 FADS3 FADS2	1.32e-07	7	47	3	EFO_0021472
Disease	level of Phosphatidylethanolamine (O-18:1_18:2) in blood serum	FADS1 FADS3 FADS2	2.11e-07	8	47	3	OBA_2045147
Disease	phosphatidylcholine 39:5 measurement	FADS1 FADS3 FADS2	3.16e-07	9	47	3	EFO_0021476
Disease	level of Phosphatidylcholine (18:2_20:1) in blood serum	FADS1 FADS3 FADS2	3.16e-07	9	47	3	OBA_2045107
Disease	level of Phosphatidylcholine (O-18:1_18:2) in blood serum	FADS1 FADS3 FADS2	3.16e-07	9	47	3	OBA_2045129
Disease	level of Phosphatidylcholine (O-18:1_20:3) in blood serum	FADS1 FADS3 FADS2	3.16e-07	9	47	3	OBA_2045130
Disease	level of Phosphatidylcholine (18:0_20:5) in blood serum	FADS1 FADS3 FADS2	3.16e-07	9	47	3	OBA_2045095
Disease	cholesteryl ester 22:4 measurement	FADS1 FADS3 FADS2	4.51e-07	10	47	3	EFO_0021443
Disease	cholesteryl ester 22:5 measurement	FADS1 FADS3 FADS2	4.51e-07	10	47	3	EFO_0021444
Disease	level of Phosphatidylcholine (O-16:1_20:4) in blood serum	FADS1 FADS3 FADS2	6.19e-07	11	47	3	OBA_2045123
Disease	lysophosphatidylcholine 20:2 measurement	FADS1 FADS3 FADS2	6.19e-07	11	47	3	EFO_0021458
Disease	cholesteryl ester 20:2 measurement	FADS1 FADS3 FADS2	8.25e-07	12	47	3	EFO_0021440
Disease	level of Phosphatidylcholine (O-16:0_20:4) in blood serum	FADS1 FADS3 FADS2	1.07e-06	13	47	3	OBA_2045116
Disease	level of Phosphatidylcholine (16:0_18:3) in blood serum	FADS1 FADS3 FADS2	1.07e-06	13	47	3	OBA_2045072
Disease	level of Phosphatidylcholine (18:1_20:2) in blood serum	FADS1 FADS3 FADS2	1.36e-06	14	47	3	OBA_2045102
Disease	diacylglycerol 38:4 measurement	FADS1 FADS3 FADS2	1.36e-06	14	47	3	EFO_0020066
Disease	level of Phosphatidylcholine (O-18:1_20:4) in blood serum	FADS1 FADS3 FADS2	1.70e-06	15	47	3	OBA_2045131
Disease	cis/trans-18:2 fatty acid measurement, trans fatty acid measurement	FADS1 FADS3 FADS2	1.70e-06	15	47	3	EFO_0006821, EFO_0006824
Disease	level of Phosphatidylcholine (16:0_16:0) in blood serum	FADS1 FADS2 SNX13	1.70e-06	15	47	3	OBA_2045067
Disease	oleoyl-arachidonoyl-glycerol (18:1/20:4) [2] measurement	FADS1 FADS3 FADS2	1.70e-06	15	47	3	EFO_0800508
Disease	phosphatidylcholine 36:4 measurement	FADS1 FADS3 FADS2	3.04e-06	18	47	3	EFO_0010382
Disease	level of Phosphatidylcholine (20:4_0:0) in blood serum	FADS1 FADS3 FADS2	3.04e-06	18	47	3	OBA_2045110
Disease	diacylglycerol 38:5 measurement	FADS1 FADS3 FADS2	3.60e-06	19	47	3	EFO_0020067
Disease	diacylglycerol 38:3 measurement	FADS1 FADS3 FADS2	3.60e-06	19	47	3	EFO_0020065
Disease	level of Phosphatidylcholine (18:1_20:4) in blood serum	FADS1 FADS3 FADS2	4.94e-06	21	47	3	OBA_2045104
Disease	level of Phosphatidylinositol (18:0_18:2) in blood serum	FADS1 FADS3 FADS2	4.94e-06	21	47	3	OBA_2045156
Disease	level of Phosphatidylcholine (16:0_20:4) in blood serum	FADS1 FADS3 FADS2	4.94e-06	21	47	3	OBA_2045076
Disease	level of Phosphatidylinositol (18:0_20:4) in blood serum	FADS1 FADS3 FADS2	6.56e-06	23	47	3	OBA_2045158
Disease	phosphatidylserines measurement	FADS1 FADS3 FADS2	6.56e-06	23	47	3	EFO_0020049
Disease	gamma-linolenic acid measurement	FADS1 FADS2 SNX13	7.49e-06	24	47	3	EFO_0007762
Disease	alpha-linolenic acid measurement	FADS1 FADS3 FADS2	8.50e-06	25	47	3	EFO_0007759
Disease	level of Phosphatidylcholine (17:0_20:4) in blood serum	FADS1 FADS3 FADS2	9.60e-06	26	47	3	OBA_2045087
Disease	docosapentaenoic acid measurement	FADS1 FADS3 FADS2	1.08e-05	27	47	3	EFO_0006809
Disease	level of Phosphatidylethanolamine (18:0_18:2) in blood serum	FADS1 FADS3 FADS2	1.21e-05	28	47	3	OBA_2045139
Disease	lysophosphatidylethanolamine 20:4 measurement	FADS1 FADS3 FADS2	1.34e-05	29	47	3	EFO_0010370
Disease	Palmitoyl-arachidonoyl-glycerol (16:0/20:4) [2] measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0022103
Disease	Sphingomyelin (d18:2/14:0, d18:1/14:1) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0022114
Disease	phosphatidylcholine acyl-alkyl C38:5 measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0801299
Disease	phosphatidylcholine acyl-alkyl C36:4 measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0801292
Disease	phosphatidylcholine acyl-alkyl C36:2 measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0801290
Disease	phosphatidylcholine diacyl C38:5 measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0801267
Disease	phosphatidylcholine diacyl C38:4 measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0801266
Disease	phosphatidylcholine diacyl C36:4 measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0801260
Disease	phosphatidylcholine diacyl C40:6 measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0801274
Disease	2-arachidonoylglycerol (20:4) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800182
Disease	phosphatidylcholine diacyl C36:3 measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0801259
Disease	phosphatidylcholine diacyl C34:4 measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0801255
Disease	2-linoleoyl-GPC (18:2) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800239
Disease	level of Phosphatidylcholine (O-16:0_22:5) in blood serum	FADS1 FADS2	1.49e-05	4	47	2	OBA_2045117
Disease	1-dihomo-linoleoyl-GPC (20:2) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800236
Disease	sphingomyeline C16:1 measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0801318
Disease	docosapentaenoate (n6 DPA; 22:5n6) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800249
Disease	1-linoleoyl-2-linolenoyl-GPC (18:2/18:3) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800483
Disease	eicosapentaenoylcholine measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800482
Disease	comprehensive strength index, muscle measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0004515, EFO_0004979
Disease	1-stearoyl-2-adrenoyl-GPC (18:0/22:4) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800459
Disease	1-palmitoyl-2-meadoyl-GPC (16:0/20:3n9) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800458
Disease	phosphatidylcholine (18:0/20:5, 16:0/22:5n6) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800468
Disease	1-stearoyl-2-meadoyl-GPC (18:0/20:3n9) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800463
Disease	1-pentadecanoyl-2-arachidonoyl-GPC (15:0/20:4) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800446
Disease	1-palmitoyl-2-alpha-linolenoyl-GPC (16:0/18:3n3) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800442
Disease	1-palmitoyl-2-eicosapentaenoyl-GPC (16:0/20:5) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800408
Disease	phosphatidylcholine 33:2 measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0021470
Disease	phosphatidylcholine 33:1 measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0021469
Disease	1-linoleoyl-2-docosahexaenoyl-GPC (18:2/22:6) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0022080
Disease	1-margaroyl-2-arachidonoyl-GPC (17:0/20:4) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0022081
Disease	1-arachidoyl-2-arachidonoyl-GPC (20:0/20:4) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0022079
Disease	1,2-dilinoleoyl-GPC (18:2/18:2) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800388
Disease	1-eicosapentaenoyl-GPC (20:5) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800355
Disease	phosphatidylcholine (O-18:1/20:4, O-16:0/22:5n3) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800553
Disease	1-(1-enyl-stearoyl)-GPC (P-18:0) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800325
Disease	1-(1-enyl-oleoyl)-GPC (P-18:1) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800324
Disease	1-lignoceroyl-GPC (24:0) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800322
Disease	1-adrenoyl-GPC (22:4) measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0800321
Disease	arachidonate 20:4n6-to-dihomo-linolenate 20:3n3 or n6 ratio	FADS1 FADS2	1.49e-05	4	47	2	EFO_0021517
Disease	fatty acid measurement, linolenic acid measurement	FADS1 FADS2	1.49e-05	4	47	2	EFO_0005110, EFO_0006811
Disease	eicosapentaenoic acid measurement	FADS1 FADS3 FADS2	1.65e-05	31	47	3	EFO_0007760
Disease	level of Sterol ester (27:1/20:4) in blood serum	FADS1 FADS3 FADS2	1.65e-05	31	47	3	OBA_2045198
Disease	level of Phosphatidylcholine (18:0_20:4) in blood serum	FADS1 FADS3 FADS2	1.65e-05	31	47	3	OBA_2045094
Disease	lysophosphatidylcholine 20:4 measurement	FADS1 FADS3 FADS2	1.82e-05	32	47	3	EFO_0010363
Disease	cholesteryl ester 22:6 measurement	FADS1 FADS3 FADS2	1.82e-05	32	47	3	EFO_0010350
Disease	phosphatidylcholine 38:5 measurement	FADS1 FADS3 FADS2	2.00e-05	33	47	3	EFO_0010387
Disease	triglyceride measurement, alcohol consumption measurement	FADS1 FADS2 SMIM20 SNX13	2.06e-05	101	47	4	EFO_0004530, EFO_0007878
Disease	phosphatidylcholine 38:2 measurement	FADS1 FADS3 FADS2	2.39e-05	35	47	3	EFO_0010384
Disease	phosphatidylcholine acyl-alkyl C36:5 measurement	FADS1 FADS2	2.48e-05	5	47	2	EFO_0801293
Disease	2-arachidonoyl-GPC (20:4) measurement	FADS1 FADS2	2.48e-05	5	47	2	EFO_0800237
Disease	1-arachidonoyl-GPC (20:4n6) measurement	FADS1 FADS2	2.48e-05	5	47	2	EFO_0800234
Disease	sphingomyeline C18:1 measurement	FADS1 FADS2	2.48e-05	5	47	2	EFO_0801320
Disease	1-palmitoleoyl-2-linolenoyl-GPC (16:1/18:3) measurement	FADS1 FADS2	2.48e-05	5	47	2	EFO_0800484
Disease	phosphatidylcholine (16:0/22:5n3, 18:1/20:4) measurement	FADS1 FADS2	2.48e-05	5	47	2	EFO_0800467
Disease	1-linoleoyl-GPC (18:2) measurement	FADS1 FADS2	2.48e-05	5	47	2	EFO_0800223
Disease	1-(1-enyl-stearoyl)-2-arachidonoyl-GPE (P-18:0/20:4) measurement	FADS1 FADS2	2.48e-05	5	47	2	EFO_0800415
Disease	1-palmitoyl-2-dihomo-linolenoyl-GPC (16:0/20:3n3 or 6) measurement	FADS1 FADS2	2.48e-05	5	47	2	EFO_0800407
Disease	1-(1-enyl-palmitoyl)-2-arachidonoyl-GPE (P-16:0/20:4) measurement	FADS1 FADS2	2.48e-05	5	47	2	EFO_0800417
Disease	cholesteryl ester 20:1 measurement	FADS2 ELOVL7	2.48e-05	5	47	2	EFO_0021439
Disease	1-linolenoyl-GPE (18:3) measurement	FADS1 FADS2	2.48e-05	5	47	2	EFO_0800365

Protein segments in the cluster

Peptide	Gene	Start	Entry
ILIYLVIAFSPFGYF	ABCA5	221	Q8WWZ7
RVLFYLGPVYLAGYL	ESYT3	41	A0FGR9
AFYFPTLLLIALYGR	HTR1B	216	P28222
HGIYTSLVLFFIPYG	ATP8B4	961	Q8TF62
YLLFRPFKGYEGSLI	RBPMS	41	Q93062
FYGSIFFLYIRPNLL	OR5K2	251	Q8NHB8
FFITYIPFYGILGAL	FADS2	306	O95864
GLVYFLYLFLFSGLE	MFSD10	276	Q14728
VLLFYGTIVGVYFFP	OR1S1	261	Q8NH92
LYIGFLGLIFSSYFV	KCNQ1	266	P51787
FYIPGLFSYLTHRFG	OR52W1	256	Q6IF63
IYGFFLLFRGFFPVV	GOLT1B	91	Q9Y3E0
YHGKLLDGFFIRPFY	NEDD4	1066	P46934
LLGFLLPSYLFYYRA	SLC43A1	521	O75387
YAPLAFRYFRELFGI	PIP5K1B	86	O14986
PFTYFFYLVFLVGII	GPR171	16	O14626
PIYGFGIFLYILYIL	RIC3	101	Q7Z5B4
YPFLFDNLPLFYRLG	PAQR6	191	Q6TCH4
IYGIASFFFLYGIIL	GPM6B	91	Q13491
GLRIPLFFLFLGFYT	OR8B12	21	Q8NGG6
LGFYVYFVTSLGPKL	ELOVL7	41	A1L3X0
GVIFLSLLSGRYPFY	CDC7	401	O00311
IVGHYFLYGFRILPL	GJA8	166	P48165
TFYVRFFLTYVPLLG	FADS1	301	O60427
LPTRRGFDTYFGYLL	ARSB	156	P15848
GFYQLGIPFLSYFPL	FOXL1	321	Q12952
YLGAYVFIIFTGFLI	SLC2A3	426	P11169
LTGLYGFIFYLLASV	EMC6	46	Q9BV81
RFFLSYLPFYGVPGV	FADS3	306	Q9Y5Q0
YLPFYGVPGVLLFFV	FADS3	311	Q9Y5Q0
ALFYGSIIYVYFRPL	OR1L6	286	Q8NGR2
NYYRFLVGFLFPICL	GPR68	186	Q15743
LITFGPFVIFYLTFY	SNX13	21	Q9Y5W8
LPLFYGSIVRFFLYG	SMCHD1	621	A6NHR9
FFNILLPPIIFYAGY	SLC9A6	151	Q92581
LGFFFLLLPYFSYLR	SPATA31C2	36	B4DYI2
LGGIYKFITERFPFY	FOXE1	76	O00358
GTYLLIFGAFLIYVA	LMBRD2	156	Q68DH5
LGFFFLLLPYLSYFR	SPATA31A7	36	Q8IWB4
FFYLLPPIVLDAGYF	SLC9A3	116	P48764
PIERLVSYYYFLRFG	HS2ST1	166	Q7LGA3
FLYLLPPIVLEGGYF	SLC9A4	131	Q6AI14
SLIGAAFYPIYFRPL	SMIM20	16	Q8N5G0
LGLFFLLLPYFSYLR	SPATA31C1	36	P0DKV0
IIFYFVFSLFYGGIL	ATP11B	1036	Q9Y2G3
LGFFFLLLPYLSYFR	SPATA31A3	36	Q5VYP0
LGFFFLLLPYLSYFR	SPATA31A1	36	Q5TZJ5
LGFFFLLLPYLSYFR	SPATA31A5	36	Q5VU36
FFLYLLPPIVLDAGY	SLC9A2	141	Q9UBY0
FLTEYAGPLFIYLLF	TECR	91	Q9NZ01
AGPLFIYLLFYFRVP	TECR	96	Q9NZ01
LYAGIGYFTLPFLVH	TRMT12	241	Q53H54
EYLGLPSVYLFRGFP	UGT1A6	161	P19224
PVFGLYGSLFPAIIY	SLC26A7	76	Q8TE54
FLLGLFGYLVFLVIY	TCIRG1	576	Q13488
LGILFLIVYYGSFHP	XKR9	331	Q5GH70