Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RS domain binding	SRSF5 SON SRSF12	4.88e-06	8	90	3	GO:0050733
GeneOntologyCellularComponent	chromosomal region	ORC1 ATR CENPC BAZ1A AHCTF1 NCAPD2 TRIOBP DAXX NSMCE4A	8.37e-05	421	90	9	GO:0098687
Domain	Kinesin_motor_CS	KIF21B KIF23 KIFC2	8.56e-04	41	85	3	IPR019821
Domain	Kinesin-like_fam	KIF21B KIF23 KIFC2	9.84e-04	43	85	3	IPR027640
Domain	KINESIN_MOTOR_1	KIF21B KIF23 KIFC2	1.05e-03	44	85	3	PS00411
Domain	-	KIF21B KIF23 KIFC2	1.05e-03	44	85	3	3.40.850.10
Domain	Kinesin_motor_dom	KIF21B KIF23 KIFC2	1.05e-03	44	85	3	IPR001752
Domain	Kinesin	KIF21B KIF23 KIFC2	1.05e-03	44	85	3	PF00225
Domain	KINESIN_MOTOR_2	KIF21B KIF23 KIFC2	1.05e-03	44	85	3	PS50067
Domain	KISc	KIF21B KIF23 KIFC2	1.05e-03	44	85	3	SM00129
Domain	TF_fork_head_CS_2	FOXD4L4 FOXD4L1 FOXD4L5	1.20e-03	46	85	3	IPR030456
Domain	TF_fork_head_CS_1	FOXD4L4 FOXD4L1 FOXD4L5	1.28e-03	47	85	3	IPR018122
Domain	FH	FOXD4L4 FOXD4L1 FOXD4L5	1.44e-03	49	85	3	SM00339
Domain	FORK_HEAD_1	FOXD4L4 FOXD4L1 FOXD4L5	1.44e-03	49	85	3	PS00657
Domain	FORK_HEAD_2	FOXD4L4 FOXD4L1 FOXD4L5	1.44e-03	49	85	3	PS00658
Domain	Fork_head_dom	FOXD4L4 FOXD4L1 FOXD4L5	1.44e-03	49	85	3	IPR001766
Domain	FORK_HEAD_3	FOXD4L4 FOXD4L1 FOXD4L5	1.44e-03	49	85	3	PS50039
Domain	Forkhead	FOXD4L4 FOXD4L1 FOXD4L5	1.44e-03	49	85	3	PF00250
Domain	RasGAP	DAB2IP RASAL3	1.80e-03	14	85	2	SM00323
Domain	RasGAP_CS	DAB2IP RASAL3	1.80e-03	14	85	2	IPR023152
Domain	RasGAP	DAB2IP RASAL3	2.07e-03	15	85	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	DAB2IP RASAL3	2.07e-03	15	85	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	DAB2IP RASAL3	2.07e-03	15	85	2	PS50018
Domain	-	DAB2IP RASAL3	2.36e-03	16	85	2	1.10.506.10
Domain	RasGAP_dom	DAB2IP RASAL3	2.99e-03	18	85	2	IPR001936
Domain	Zinc_finger_PHD-type_CS	ING2 BAZ1A KDM2A	3.24e-03	65	85	3	IPR019786
Domain	Hemopexin-like_dom	VTN MMP21	4.87e-03	23	85	2	IPR000585
Domain	Hemopexin-like_repeat	VTN MMP21	4.87e-03	23	85	2	IPR018487
Domain	Hemopexin	VTN MMP21	4.87e-03	23	85	2	PF00045
Domain	HEMOPEXIN	VTN MMP21	4.87e-03	23	85	2	PS00024
Domain	-	VTN MMP21	4.87e-03	23	85	2	2.110.10.10
Domain	HEMOPEXIN_2	VTN MMP21	4.87e-03	23	85	2	PS51642
Domain	HX	VTN MMP21	4.87e-03	23	85	2	SM00120
Domain	Znf_PHD-finger	ING2 BAZ1A KDM2A	5.61e-03	79	85	3	IPR019787
Domain	PHD	ING2 BAZ1A KDM2A	7.80e-03	89	85	3	SM00249
Domain	Znf_PHD	ING2 BAZ1A KDM2A	8.29e-03	91	85	3	IPR001965
Domain	PH	DAB2IP RASAL3 DGKK TRIOBP PLEKHG2	8.79e-03	278	85	5	SM00233
Domain	PH_DOMAIN	DAB2IP RASAL3 DGKK TRIOBP PLEKHG2	8.92e-03	279	85	5	PS50003
Domain	PH_domain	DAB2IP RASAL3 DGKK TRIOBP PLEKHG2	9.05e-03	280	85	5	IPR001849
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	SCAF1 KIF23 SRSF5 FXR2 BAZ1A ZC3H13 BUD13 PRPF38B MAP3K21 SRRM2 SPEN RRP1 SON	1.61e-11	361	93	13	26167880
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SCAF1 KIF23 SRSF5 ATR NACC1 CTR9 ZC3H13 BUD13 PRPF38B DAXX DDX51 SRRM2 SPEN C2CD5 SON	2.22e-09	774	93	15	15302935
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ORC1 SCAF1 SLX9 KIF23 SRSF5 ATR ING2 BAZ1A CTR9 ZC3H13 AHCTF1 KDM2A DDX51 SRRM2 SPEN RRP1 SON	5.39e-08	1294	93	17	30804502
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	KIF23 SRSF5 FXR2 TJP1 ZC3H13 AHCTF1 NCAPD2 DDX51 SRRM2 SPEN RRP1 SON	1.81e-07	653	93	12	22586326
Pubmed	Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.	FOXD4L4 FOXD4L1 FOXD4L5	3.68e-07	6	93	3	27092474
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SCAF1 CTR9 ZC3H13 BUD13 PRPF38B SPEN RRP1 SRSF12	3.95e-07	251	93	8	31076518
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	CCPG1 KIF23 SRSF5 FXR2 BAZ1A TJP1 ZC3H13 AHCTF1 NOL12 DDX51 SRRM2 RRP1 SON	4.18e-07	847	93	13	35850772
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	SRSF5 FXR2 CTR9 ZC3H13 BUD13 PRPF38B DDX51 SRRM2 SPEN RRP1 SON SRSF12	5.98e-07	731	93	12	29298432
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	DAB2IP SLX9 KIF23 CTR9 ZC3H13 AHCTF1 NCAPD2 SRRM2 SPEN SON	1.01e-06	503	93	10	16964243
Pubmed	The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.	FOXD4L4 FOXD4L1 FOXD4L5	1.03e-06	8	93	3	8530406
Pubmed	An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.	FOXD4L4 FOXD4L1 FOXD4L5	1.54e-06	9	93	3	12412011
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SLX9 KIF23 CENPC BAZ1A TJP1 ZC3H13 AHCTF1 BUD13 SRRM2 SPEN SON NSMCE4A SRSF12	1.57e-06	954	93	13	36373674
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SCAF1 RASAL3 FXR2 NACC1 AHCTF1 NOL12 FBRSL1 MMP21 BUD13 CRACR2B SRRM2 CEP170B C2CD5 SON	1.59e-06	1116	93	14	31753913
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	KIF23 CENPC AHCTF1 NOL12 NCAPD2 SRRM2 SON	1.62e-06	210	93	7	16565220
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ORC1 SCAF1 BAZ1A ATP13A1 CTR9 AHCTF1 NCAPD2 TRIOBP BUD13 PRPF38B DAXX DDX51 SPEN CEP170B RRP1 SON	2.13e-06	1497	93	16	31527615
Pubmed	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.	FOXD4L4 FOXD4L1 FOXD4L5	5.19e-06	13	93	3	7957066
Pubmed	A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.	FOXD4L4 FOXD4L1 FOXD4L5	5.19e-06	13	93	3	16884697
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	SLX9 KIF23 CENPC BAZ1A NACC1 AHCTF1 KDM2A DAXX SPEN RRP1	5.45e-06	608	93	10	36089195
Pubmed	SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.	SCAF1 SRSF5 ATP13A1 AHCTF1 BUD13 SRRM2 SON	6.43e-06	259	93	7	30404004
Pubmed	Mutations in a novel isoform of TRIOBP that encodes a filamentous-actin binding protein are responsible for DFNB28 recessive nonsyndromic hearing loss.	NOL12 TRIOBP	7.07e-06	2	93	2	16385458
Pubmed	SON and SRRM2 are essential for nuclear speckle formation.	SRRM2 SON	7.07e-06	2	93	2	33095160
Pubmed	Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death.	CENPC DAXX	7.07e-06	2	93	2	9645950
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DAB2IP RABL6 ORC1 GAS2L1 SCAF1 HIVEP2 ATP13A1 NCAPD2 FBRSL1 SPEN KIFC2 CRAMP1 CEP170B	7.74e-06	1105	93	13	35748872
Pubmed	Six members of the mouse forkhead gene family are developmentally regulated.	FOXD4L4 FOXD4L1 FOXD4L5	8.23e-06	15	93	3	7689224
Pubmed	Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.	FOXD4L4 FOXD4L1 FOXD4L5	8.23e-06	15	93	3	22045912
Pubmed	Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.	FOXD4L4 FOXD4L1 FOXD4L5	1.01e-05	16	93	3	8861101
Pubmed	Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.	FOXD4L4 FOXD4L1 FOXD4L5	1.01e-05	16	93	3	10208738
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SRSF5 FXR2 ZC3H13 NOL12 FBRSL1 DDX51 SRRM2 SPEN RRP1 SON SRSF12	1.06e-05	807	93	11	22681889
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	KIF21B KIF23 SRSF5 FXR2 BAZ1A TJP1 CTR9 KDM2A SRRM2 RRP1	1.11e-05	660	93	10	32780723
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	ORC1 SCAF1 KIF23 CENPC NACC1 CTR9 KDM2A DAXX DDX51 SRRM2 RRP1 SON	1.32e-05	989	93	12	36424410
Pubmed	Functional equivalency between Otx2 and Otx1 in development of the rostral head.	FOXD4L4 FOXD4L1 FOXD4L5	1.74e-05	19	93	3	9895322
Pubmed	Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.	FOXD4L4 FOXD4L1 FOXD4L5	2.04e-05	20	93	3	12812790
Pubmed	Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.	FOXD4L4 FOXD4L1 FOXD4L5	2.38e-05	21	93	3	9449667
Pubmed	Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.	FOXD4L4 FOXD4L1 FOXD4L5	2.75e-05	22	93	3	17389379
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	KIF23 FXR2 TJP1 AHCTF1 DDX51 RRP1 SON	3.18e-05	332	93	7	25693804
Pubmed	Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.	FOXD4L4 FOXD4L1 FOXD4L5	3.60e-05	24	93	3	11820816
Pubmed	A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.	FOXD4L4 FOXD4L1 FOXD4L5	3.60e-05	24	93	3	29992973
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	SRSF5 FXR2 BAZ1A CTR9 ZC3H13 DDX51 SRRM2 SPEN RRP1	3.61e-05	605	93	9	28977666
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	SLX9 KIF23 SRSF5 FXR2 BAZ1A BUD13 DDX51 RRP1 SON NSMCE4A	3.66e-05	759	93	10	35915203
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	DAB2IP CACNA1E FBXO41 HCN2 SRRM2 CEP170B C2CD5	4.21e-05	347	93	7	17114649
Pubmed	Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.	FOXD4L4 FOXD4L1 FOXD4L5	4.60e-05	26	93	3	15857913
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	SLX9 KIF23 ING2 FXR2 AHCTF1 NOL12 DAXX DDX51 SRRM2 RRP1 SON	4.68e-05	949	93	11	36574265
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	HJV KIF21B SCAF1 KIF23 SRSF5 CENPC ATP13A1 NACC1 CTR9 PRPF38B KDM2A CRAMP1 C2CD5	5.22e-05	1327	93	13	32694731
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DAB2IP KIF21B CACNA1E KIF23 FXR2 TJP1 NACC1 FBXO41 TRIOBP HCN2 CEP170B	5.34e-05	963	93	11	28671696
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	SCAF1 SLX9 BAZ1A CTR9 BUD13 SPEN	6.00e-05	251	93	6	28077445
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	ORC1 ATR BAZ1A NACC1 AHCTF1 NOL12 DDX51	6.30e-05	370	93	7	22922362
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ORC1 SLX9 KIF23 CCDC22 CENPC BAZ1A CTR9 AHCTF1 NCAPD2 KDM2A DDX51 SRRM2 SON	6.36e-05	1353	93	13	29467282
Pubmed	Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow.	FOXD4L4 FOXD4L1 FOXD4L5	6.43e-05	29	93	3	22972626
Pubmed	Galanin receptor 3 - A new pharmacological target in retina degeneration.	RDH8 GALR3	7.04e-05	5	93	2	36693600
Pubmed	FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines.	FOXD4L4 FOXD4L5	7.04e-05	5	93	2	12234674
Pubmed	A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.	RABL6 SLX9 FXR2 TJP1 SRRM2	7.70e-05	162	93	5	31363146
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIF21B MAST4 NCAPD2 FBRSL1 FBXO41 TRIOBP CRAMP1 GPATCH2L	8.92e-05	529	93	8	14621295
Pubmed	The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.	SRSF5 ZC3H13 SRRM2 SON SRSF12	9.40e-05	169	93	5	23084401
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	DAB2IP RABL6 PPP1R3D SLX9 SRSF5 TJP1 NACC1 CTR9 FBRSL1 DAXX GPATCH2L	1.04e-04	1038	93	11	26673895
Pubmed	A coactivator of pre-mRNA splicing.	SRSF5 SRRM2	1.05e-04	6	93	2	9531537
Pubmed	Quantitative analysis of cell allocation during liver development, using the spf(ash)-heterozygous female mouse.	GJB1 TJP1	1.05e-04	6	93	2	10623655
Pubmed	The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.	SCAF1 SRSF5 FXR2 CTR9 NOL12 DDX51 RRP1	1.32e-04	417	93	7	36537216
Pubmed	Identification of UHRF1/2 as new N-methylpurine DNA glycosylase-interacting proteins.	FXR2 PRPF38B KDM2A	1.46e-04	38	93	3	23537643
Pubmed	Induced Mist1 expression promotes remodeling of mouse pancreatic acinar cells.	GJB1 TJP1	1.47e-04	7	93	2	22510200
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	SRSF5 TJP1 ZC3H13 NOL12 TRIOBP BUD13 PRPF38B SRRM2 SPEN RRP1 SON	1.49e-04	1082	93	11	38697112
Pubmed	Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged.	GJB1 TJP1	2.52e-04	9	93	2	20089884
Pubmed	Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.	SRSF5 FXR2 SPEN SON	2.55e-04	114	93	4	31553912
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	PPP1R3D ORC1 LTBP2 HCN2 SPEN KIFC2	2.62e-04	329	93	6	17474147
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	KIF23 BAZ1A CTR9 NCAPD2 DAXX SRRM2	2.75e-04	332	93	6	32786267
Pubmed	Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase.	KIF23 CENPC ZC3H13	2.76e-04	47	93	3	15009096
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	SLX9 KIF23 CCDC22 BAZ1A PRPF38B KDM2A SRRM2	2.81e-04	472	93	7	38943005
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	SCAF1 SLX9 VTN SRSF5 FXR2 BAZ1A TJP1 ATP13A1 AHCTF1 PRPF38B RRP1 SON	2.93e-04	1371	93	12	36244648
Pubmed	Gene content and function of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regions.	FOXD4L4 FOXD4L1	3.83e-04	11	93	2	12421752
Pubmed	Cloning of the genes encoding two murine and human cochlear unconventional type I myosins.	MAST4 SPEN	3.83e-04	11	93	2	9119401
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	KIF23 ATR CENPC BAZ1A NACC1 CTR9 NCAPD2 PRPF38B KDM2A SON	3.85e-04	1014	93	10	32416067
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	CACNA1E SCAF1 CCPG1 SRRM2 CRAMP1	4.16e-04	233	93	5	37704626
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	SRSF5 ZC3H13 AHCTF1 TRIOBP SRRM2 SON	4.28e-04	361	93	6	30344098
Pubmed	Intrinsically Disordered Protein TEX264 Mediates ER-phagy.	RABL6 CCPG1 CTR9 DAXX	4.33e-04	131	93	4	31006538
Pubmed	A high-density association screen of 155 ion transport genes for involvement with common migraine.	CACNA1E KCNQ3	4.59e-04	12	93	2	18676988
Pubmed	A novel SR-related protein is required for the second step of Pre-mRNA splicing.	SRSF5 SON	4.59e-04	12	93	2	15798186
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CACNA1E CENPC BAZ1A TJP1 CTR9 DGKK SHB NCAPD2 MMP21 SPEN C2orf78 NSMCE4A	4.62e-04	1442	93	12	35575683
Pubmed	Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation.	RABL6 SCAF1 FXR2 RRP1	4.72e-04	134	93	4	28695742
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KIF23 HIVEP2 MAST4 TJP1 PLEKHG2 MAP3K21 SRRM2 CEP170B WNK4	5.04e-04	861	93	9	36931259
Pubmed	The vertebrate-specific Kinesin-6, Kif20b, is required for normal cytokinesis of polarized cortical stem cells and cerebral cortex size.	KIF23 TJP1	5.41e-04	13	93	2	24173802
Pubmed	A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins).	SRSF5 SRSF12	5.41e-04	13	93	2	20516191
Pubmed	The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice.	GJB1 TJP1	6.30e-04	14	93	2	29361518
Pubmed	Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors.	GJB1 TJP1	6.30e-04	14	93	2	16103213
Pubmed	Comparative analyses of the Dominant megacolon-SOX10 genomic interval in mouse and human.	GALR3 TRIOBP	6.30e-04	14	93	2	10384052
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KIF23 CCDC22 TJP1 AHCTF1 NCAPD2 KDM2A SPEN	6.91e-04	549	93	7	38280479
Pubmed	Nucleosome-interacting proteins regulated by DNA and histone methylation.	ORC1 KDM2A	7.26e-04	15	93	2	21029866
Pubmed	RGS12 polarizes the GPSM2-GNAI complex to organize and elongate stereocilia in sensory hair cells.	TJP1 TRIOBP	7.26e-04	15	93	2	36260679
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	FXR2 TJP1 TRIOBP KDM2A DAXX SPEN SON NSMCE4A	7.30e-04	724	93	8	36232890
Pubmed	Genome-scale study of transcription factor expression in the branching mouse lung.	FOXD4L4 FOXD4L1 FOXD4L5	7.83e-04	67	93	3	22711520
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	RABL6 SCAF1 ING2 FXR2 CTR9 ZC3H13 AHCTF1 PRPF38B SRRM2 RRP1 SON	7.88e-04	1318	93	11	30463901
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	ORC1 KIF23 SRSF5 CENPC TJP1 AHCTF1 TRIOBP BUD13 CEP170B NSMCE4A	1.05e-03	1155	93	10	20360068
Pubmed	M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP.	FBXO41 KDM2A	1.05e-03	18	93	2	15070733
Pubmed	From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map.	SLX9 SON	1.05e-03	18	93	2	11707072
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	DAB2IP CACNA1E FXR2 FBXO41 HCN2 CEP170B	1.06e-03	430	93	6	32581705
Pubmed	Pericytes are required for blood-brain barrier integrity during embryogenesis.	VTN TJP1	1.17e-03	19	93	2	20944625
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	SCAF1 KIF23 SRSF5 ATR BAZ1A ATP13A1 CTR9 NCAPD2 SRRM2 SPEN RRP1	1.48e-03	1425	93	11	30948266
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	SRSF5 ATR FXR2 ZC3H13 FBXO41 WNK4	1.53e-03	462	93	6	31138677
Pubmed	Diverse fates of paralogs following segmental duplication of telomeric genes.	FOXD4L4 FOXD4L1	1.58e-03	22	93	2	15233989
Pubmed	DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system.	ORC1 ATR	1.58e-03	22	93	2	15707391
Pubmed	EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia.	TJP1 GPR156	1.58e-03	22	93	2	34001891
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	KIF23 CCDC22 SRSF5 CENPC KDM2A SPEN RRP1	1.75e-03	645	93	7	25281560
Interaction	SRSF6 interactions	SCAF1 KIF23 SRSF5 CENPC ZC3H13 NOL12 BUD13 PRPF38B DAXX DDX51 SRRM2 SPEN SON SRSF12	4.84e-08	503	90	14	int:SRSF6
Interaction	SAP18 interactions	SCAF1 KIF23 VTN CCDC22 SRSF5 ZC3H13 NOL12 PRPF38B SRRM2 SON	1.07e-06	305	90	10	int:SAP18
Interaction	MEN1 interactions	CCPG1 KIF23 SRSF5 FXR2 BAZ1A TJP1 ZC3H13 AHCTF1 NOL12 NCAPD2 KDM2A DAXX DDX51 SRRM2 SPEN RRP1 SON	2.62e-06	1029	90	17	int:MEN1
Interaction	SRPK2 interactions	SCAF1 SRSF5 FXR2 BAZ1A ZC3H13 BUD13 PRPF38B DDX51 SRRM2 SPEN RRP1 SON NSMCE4A SRSF12	3.39e-06	717	90	14	int:SRPK2
Interaction	LINC02910 interactions	RABL6 SLX9 ZC3H13 BUD13 PRPF38B RRP1	4.23e-06	95	90	6	int:LINC02910
Interaction	NLE1 interactions	SRSF5 CENPC ZC3H13 NOL12 BUD13 SRRM2 SPEN SON	8.29e-06	228	90	8	int:NLE1
Interaction	YWHAG interactions	DAB2IP PPP1R3D KIF21B KIF23 HIVEP2 MAST4 CDCA7 BAZ1A TJP1 ZC3H13 SHB PRPF38B PLEKHG2 MAP3K21 SRRM2 CEP170B SON SRSF12	8.48e-06	1248	90	18	int:YWHAG
Interaction	MAPRE3 interactions	GAS2L1 FOXD4L4 MAST4 FOXD4L1 CENPC FXR2 KLHDC7B CEP170B	8.84e-06	230	90	8	int:MAPRE3
Interaction	FGFBP1 interactions	SCAF1 SLX9 SRSF5 BAZ1A AHCTF1 NOL12 BUD13 DDX51	1.97e-05	257	90	8	int:FGFBP1
Interaction	SIRT7 interactions	KIF23 SRSF5 ATR FXR2 TJP1 ZC3H13 AHCTF1 NCAPD2 DDX51 SRRM2 SPEN RRP1 SON	2.55e-05	744	90	13	int:SIRT7
Interaction	YWHAH interactions	DAB2IP PPP1R3D KIF21B SLX9 KIF23 HIVEP2 MAST4 CDCA7 FXR2 TJP1 ZC3H13 PLEKHG2 MAP3K21 SRRM2 CEP170B SRSF12	2.68e-05	1102	90	16	int:YWHAH
Interaction	ZC3H18 interactions	KIF23 SRSF5 FXR2 CTR9 ZC3H13 BUD13 PRPF38B DAXX DDX51 SRRM2 SPEN RRP1 SON SRSF12	3.28e-05	877	90	14	int:ZC3H18
Interaction	RAD18 interactions	SCAF1 TJP1 CTR9 ZC3H13 BUD13 PRPF38B SRRM2 SPEN RRP1 SRSF12	3.69e-05	457	90	10	int:RAD18
Interaction	CLK1 interactions	KIF23 SRSF5 ZC3H13 MAP3K21 SRRM2 SPEN SRSF12	5.66e-05	219	90	7	int:CLK1
Interaction	CLK3 interactions	SRSF5 ZC3H13 PRPF38B DAXX SRRM2 RRP1 SRSF12	5.82e-05	220	90	7	int:CLK3
Interaction	DOT1L interactions	ORC1 KIF23 SRSF5 FXR2 BAZ1A ZC3H13 AHCTF1 NOL12 DAXX DDX51 SRRM2 RRP1 SON	5.88e-05	807	90	13	int:DOT1L
Interaction	SNIP1 interactions	SCAF1 SRSF5 ATR ATP13A1 AHCTF1 BUD13 SRRM2 SON SRSF12	1.03e-04	417	90	9	int:SNIP1
Interaction	YWHAQ interactions	DAB2IP PPP1R3D KIF21B KIF23 VTN HIVEP2 MAST4 CDCA7 BAZ1A TJP1 ZC3H13 MAP3K21 CEP170B WNK4 SRSF12	1.20e-04	1118	90	15	int:YWHAQ
Interaction	RRP8 interactions	SCAF1 KIF23 SRSF5 CENPC FXR2 NOL12 DDX51	1.61e-04	259	90	7	int:RRP8
Interaction	PYHIN1 interactions	SCAF1 SLX9 BAZ1A CTR9 BUD13 DAXX SRRM2 SPEN	2.00e-04	358	90	8	int:PYHIN1
Cytoband	14q24	SRSF5 LTBP2	2.25e-04	11	94	2	14q24
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF21B KIF23 KIFC2	3.30e-04	46	53	3	622
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	DAB2IP RASAL3	3.74e-04	10	53	2	830
GeneFamily	RNA binding motif containing\|Serine and arginine rich splicing factors	SRSF5 SRSF12	5.46e-04	12	53	2	737
GeneFamily	PHD finger proteins	ING2 BAZ1A KDM2A	2.33e-03	90	53	3	88
Computational	Genes in the cancer module 397.	ORC1 KIF23 TJP1 NOL12 NCAPD2	1.75e-04	121	47	5	MODULE_397
Disease	DnaJ homolog subfamily C member 30 measurement	VTN VPS37D	5.14e-05	4	87	2	EFO_0801542
Disease	nasopharynx carcinoma (is_marker_for)	DAB2IP ATR SPEN	2.81e-04	43	87	3	DOID:9261 (is_marker_for)
Disease	prostate carcinoma	DAB2IP GDF5-AS1 GJB1 MAST4 CDCA7 FBRSL1 KDM2A MAP3K21 SPEN CRAMP1	2.94e-04	891	87	10	EFO_0001663
Disease	PROSTATE CANCER, HEREDITARY, 1	CDCA7 FBRSL1 KDM2A	7.50e-04	60	87	3	C4722327
Disease	Prostate cancer, familial	CDCA7 FBRSL1 KDM2A	1.13e-03	69	87	3	C2931456
Disease	Chronic myeloproliferative disorder	ORC1 ATR	1.42e-03	19	87	2	C1292778
Disease	anthropometric measurement	GDF5-AS1 FAM53A KDM2A LTBP2	1.56e-03	168	87	4	EFO_0004302
Disease	Seckel syndrome	ORC1 ATR	1.91e-03	22	87	2	C0265202
Disease	colon adenocarcinoma (is_marker_for)	SRSF5 DAXX	2.47e-03	25	87	2	DOID:234 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
PPRRRRRESSSQEEE	FBRSL1	66	Q9HCM7
SDSDLSPPRRRQRTK	BUD13	386	Q9BRD0
ARHVSRRPNPLASRR	C2orf78	731	A6NCI8
RRQSRSPSEGRSQTP	CACNA1E	2116	Q15878
VSDTSTPRRSRRQLP	CACNA1E	2146	Q15878
ERRRRPRDSPTLSNS	ATP13A1	891	Q9HD20
KRRPPSRRFRRSQSD	RCSD1	166	Q6JBY9
RVPRRASPLRTSRSR	ARHGEF15	236	O94989
RSNSLSTPRPTRASR	CEP170B	1111	Q9Y4F5
STPRPTRASRLRRAR	CEP170B	1116	Q9Y4F5
RTSRLPPQEDTRAQR	CCDC22	231	O60826
PRQERSTSRQRSRGS	CBY3	31	A6NI87
SQSPRTRGSRRQIQR	DAXX	176	Q9UER7
RPKQRSRRLSSRQRP	BAZ1A	1196	Q9NRL2
RTQSVPVRRPARRRQ	RASAL3	816	Q86YV0
PRAPRTSKAQRRRLT	NOL12	191	Q9UGY1
RQQRPPRSRERTAAD	RABL6	691	Q3YEC7
CPPSQRLSRSERNRR	HJV	321	Q6ZVN8
SRSRSRTRPARESPQ	DAB2IP	31	Q5VWQ8
NQTSPRRRSRRGTLS	DGKK	811	Q5KSL6
SRAESQSRQRPPLER	FXR2	616	P51116
AERPRSTPQRSLRDS	FOXD4L4	6	Q8WXT5
PRQRRSITRDSDTPL	KCNQ3	776	O43525
SHSRSPERPLQRRER	HMGN2P46	106	Q86SG4
RSRRSPRAPLSLSRR	MMP21	141	Q8N119
PRQSRATETSPLTRR	KIF21B	1206	O75037
QRTPQRYSSRRATPR	L1RE1	201	Q9UN81
DRQPRTRSTRPNRAS	LMNTD1	361	Q8N9Z9
PTRRQIRLSSPERQR	MICAL1	801	Q8TDZ2
DSSQPERSSRRPRRQ	ING2	141	Q9H160
ISSTRPPLRRQTNIR	RDH8	246	Q9NYR8
LPRRAPRTVSRNLRS	ORC1	431	Q13415
HPLRSRALRTPRNAR	GALR3	126	O60755
RRRLSSSLNPSKRAP	ATR	431	Q13535
ETSNQPSPAFRRRRA	CCPG1	166	Q9ULG6
EPRRLSSRRSVLTSP	KDM2A	381	Q9Y2K7
PSNTPNVRRTKRTRL	CENPC	731	Q03188
AAASTEPATRRRRRP	DDX51	56	Q8N8A6
RRPPALRSQSRDRLD	GAS2L1	396	Q99501
SVPSPARRARSQSRE	GAS2L1	426	Q99501
SSRSPRCPRNQASLR	CRAMP1	776	Q96RY5
RRPPSQNFARGERRS	CRACR2B	226	Q8N4Y2
RAARSKPRPRRSTAL	GDF5-AS1	86	Q5U4N7
GSPRRPRRQRSDQDS	CTR9	1071	Q6PD62
ACARRAQRRSNPPSR	GJB1	216	P08034
RRPTEAEARRPSRAQ	LTBP2	96	Q14767
SERSQPPRSSGLRRQ	FBXO41	451	Q8TF61
ENRCRNTPMRPRSRS	MAST4	341	O15021
AERPRSTPQRSLRDS	FOXD4L1	6	Q9NU39
RRRSSLHSQPPKTRR	FAM47A	486	Q5JRC9
APQTTDSRVRRPSSR	GPR156	646	Q8NFN8
SFTENAPCRPLRRRR	GPATCH2L	116	Q9NWQ4
ARRSQPVPQLRKRSR	KLHDC7B	121	Q96G42
EAPSIRRRSTRNTPA	AHCTF1	2001	Q8WYP5
ERRSRPRRQWSSSSP	CROCCP3	261	Q8IVE0
RRLSRASRPLSASQP	HCN2	811	Q9UL51
PEPRQRSRLLRSQSE	C2CD5	646	Q86YS7
VPTTARARLSRPQRA	KIFC2	801	Q96AC6
NAPPIRLRHRRSRSA	KIF23	801	Q02241
APSRRSRSPRTSILD	RTBDN	201	Q9BSG5
QSSPSPSRDRRRQLR	SHB	361	Q15464
SRTPARRRSRSRTPT	SRRM2	586	Q9UQ35
SRTPTRRRSRSRTPA	SRRM2	596	Q9UQ35
PRRRSSRSSPELTRK	SRRM2	1686	Q9UQ35
SRSRTPPVTRRRSRS	SRRM2	1946	Q9UQ35
RSLTRSPPAIRRRSA	SRRM2	2066	Q9UQ35
SRRRQDRRATPTGRP	TCP10L	191	Q8TDR4
IVPQRRPASLRSRSD	MAP3K21	941	Q5TCX8
AERPRSTPQRSLRDS	FOXD4L5	6	Q5VV16
LRRDSSQRLPVARPR	HOATZ	56	Q6PI97
RPLKASRTRQPSRTN	RMND1	146	Q9NWS8
SRSRSRSPLSPRSRR	NSMCE4A	26	Q9NXX6
RQRRRTPRPLTSARA	RRP1	431	P56182
SLPRRSTSARQSRTP	SRSF12	156	Q8WXF0
PASVDRQRSRSRSRS	SRSF5	251	Q13243
RTSSPNRATRDNPRT	TRIOBP	416	Q9H2D6
PRASRTSSPNRATRD	TRIOBP	461	Q9H2D6
RDNPRASRTSSPNRA	TRIOBP	556	Q9H2D6
SRTSSPNRATRDNPR	TRIOBP	611	Q9H2D6
RRDNPRASSRNRTIQ	TRIOBP	726	Q9H2D6
RASSRNRTIQRDNPR	TRIOBP	731	Q9H2D6
PRTSARTPERELRTQ	TRIOBP	1396	Q9H2D6
GSDSQSRRPRRRTFP	CDCA7	151	Q9BWT1
RNPERRARPLTRSRS	CDCA7	171	Q9BWT1
EPRRTTRRHPNTQQR	NCAPD2	1341	Q15021
RRGASRSPSPQSRRL	INPP5J	906	Q15735
QSRRLSRVAPDRSSN	INPP5J	916	Q15735
RTQRADTQPSRCRLP	TMEM31	41	Q5JXX7
PQRPTNLRRRSRSFT	RGS18	206	Q9NS28
EPSLPLSRTRRRNVR	SPEN	1891	Q96T58
ASRPQEPRNRSRIST	RNF111	356	Q6ZNA4
KRAPSNRPSSRSRVR	SRRM5	71	B3KS81
SPSKERQRRQSRSPN	SRRM5	526	B3KS81
RRCRSPRSEPRSQES	SCAF1	66	Q9H7N4
SLSPRRSPRRSRSRS	PRPF38B	266	Q5VTL8
PSAQRISPRRRNRNT	ZSCAN1	241	Q8NBB4
ISPRRRNRNTDQSGR	ZSCAN1	246	Q8NBB4
RASLTRTPPRASLTR	nan	441	Q9UF83
RARSLPSSPERRQKA	PPP1R3D	71	O95685
PLNTTSGSPSRRRRR	TMDD1	76	P0DPE3
SRRQARSRESNKPRP	SLX9	161	Q9NSI2
RSRESNKPRPSELSR	SLX9	166	Q9NSI2
LLRRRERSAQPAPTS	VPS37D	171	Q86XT2
RASLTRSPPTASLRR	nan	31	A8MUU9
PRASRTRTPPRTSQR	nan	111	A8MUU9
RTSQRRMPPRTSQTR	nan	121	A8MUU9
TSQTRTPPRASLRRT	nan	131	A8MUU9
SLRRTPSRASRTRTP	nan	141	A8MUU9
PRASLRRTPSRASLT	nan	156	A8MUU9
RRTPSRASLTRTPSR	nan	161	A8MUU9
RTSQTRTPPRASLRR	nan	216	A8MUU9
PRDRSASRERSLSPR	TJP1	156	Q07157
RPPRRSRSRSPDQRS	TJP1	306	Q07157
TRASANAPRRRPRVL	PLEKHG2	836	Q9H7P9
SQRDVSPRRHLSPRR	HIVEP2	2101	P31629
KRRTQTETPRPRFSR	SIGLEC10	576	Q96LC7
SRGRNQNSRRPSRAT	VTN	386	P04004
EPRPRSSRLSRRSSV	WNK4	51	Q96J92
ISPSRRSRTPSRRSR	SON	1951	P18583
RRDNRERDQRPSSPI	ZC3H13	631	Q5T200
ETPRVLSRRRQRAFP	ZNF783	336	Q6ZMS7
PSTRRRPSLSQERLA	FAM53A	216	Q6NSI3
RSSTNDPRRKPLDSR	NACC1	421	Q96RE7