Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphopyruvate hydratase activity	ENO1 ENO2 ENO3	1.31e-07	4	65	3	GO:0004634
GeneOntologyMolecularFunction	hydro-lyase activity	ACO1 ENO1 ENO2 ENO3	5.27e-05	63	65	4	GO:0016836
GeneOntologyMolecularFunction	carbon-oxygen lyase activity	ACO1 ENO1 ENO2 ENO3	1.48e-04	82	65	4	GO:0016835
GeneOntologyBiologicalProcess	NADH metabolic process	IDH3G ENO1 ENO2 ENO3	8.11e-06	42	63	4	GO:0006734
GeneOntologyBiologicalProcess	generation of precursor metabolites and energy	PHKA2 CHCHD10 PER2 ACO1 VPS54 IDH3G ENO1 ENO2 ENO3	3.10e-05	529	63	9	GO:0006091
GeneOntologyBiologicalProcess	NADH regeneration	ENO1 ENO2 ENO3	3.47e-05	21	63	3	GO:0006735
GeneOntologyBiologicalProcess	canonical glycolysis	ENO1 ENO2 ENO3	3.47e-05	21	63	3	GO:0061621
GeneOntologyBiologicalProcess	glucose catabolic process to pyruvate	ENO1 ENO2 ENO3	3.47e-05	21	63	3	GO:0061718
GeneOntologyBiologicalProcess	NAD catabolic process	ENO1 ENO2 ENO3	5.95e-05	25	63	3	GO:0019677
GeneOntologyBiologicalProcess	glycolytic process through glucose-6-phosphate	ENO1 ENO2 ENO3	5.95e-05	25	63	3	GO:0061620
GeneOntologyBiologicalProcess	NAD metabolic process	IDH3G ENO1 ENO2 ENO3	8.16e-05	75	63	4	GO:0019674
GeneOntologyBiologicalProcess	glycolytic process through fructose-6-phosphate	ENO1 ENO2 ENO3	1.15e-04	31	63	3	GO:0061615
GeneOntologyBiologicalProcess	glucose catabolic process	ENO1 ENO2 ENO3	1.26e-04	32	63	3	GO:0006007
GeneOntologyBiologicalProcess	acidic amino acid transport	NF1 PER2 VPS54 SLC7A14	1.27e-04	84	63	4	GO:0015800
GeneOntologyCellularComponent	phosphopyruvate hydratase complex	ENO1 ENO2 ENO3	1.15e-07	4	65	3	GO:0000015
MousePheno	abnormal discrimination learning	TNIK NF1 GRM5 ITPR3	4.08e-06	29	53	4	MP:0002802
MousePheno	decreased transitional stage T2 B cell number	COG6 AKAP13 SON	2.78e-05	16	53	3	MP:0009926
MousePheno	abnormal transitional stage T2 B cell morphology	COG6 AKAP13 SON	7.53e-05	22	53	3	MP:0009920
Domain	Enolase_C	ENO1 ENO2 ENO3	3.48e-08	3	62	3	PF00113
Domain	Enolase_N	ENO1 ENO2 ENO3	3.48e-08	3	62	3	PF03952
Domain	Enolase	ENO1 ENO2 ENO3	3.48e-08	3	62	3	IPR000941
Domain	Enolase_N	ENO1 ENO2 ENO3	3.48e-08	3	62	3	SM01193
Domain	Enolase_C	ENO1 ENO2 ENO3	3.48e-08	3	62	3	SM01192
Domain	Enolase_C	ENO1 ENO2 ENO3	3.48e-08	3	62	3	IPR020810
Domain	Enolase_N	ENO1 ENO2 ENO3	3.48e-08	3	62	3	IPR020811
Domain	Enolase_CS	ENO1 ENO2 ENO3	3.48e-08	3	62	3	IPR020809
Domain	ENOLASE	ENO1 ENO2 ENO3	3.48e-08	3	62	3	PS00164
Domain	-	ENO1 ENO2 ENO3	1.39e-07	4	62	3	3.30.390.10
Domain	Enolase_C-like	ENO1 ENO2 ENO3	1.39e-07	4	62	3	IPR029065
Domain	-	ENO1 ENO2 ENO3	1.39e-07	4	62	3	3.20.20.120
Domain	Enolase_N-like	ENO1 ENO2 ENO3	1.39e-07	4	62	3	IPR029017
Domain	AAA	KATNAL2 SPG7 NSF	6.86e-04	52	62	3	PF00004
Domain	ATPase_AAA_core	KATNAL2 SPG7 NSF	7.66e-04	54	62	3	IPR003959
Domain	RasGAP	NF1 RASAL3	9.62e-04	14	62	2	SM00323
Domain	RasGAP_CS	NF1 RASAL3	9.62e-04	14	62	2	IPR023152
Domain	RasGAP	NF1 RASAL3	1.11e-03	15	62	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	NF1 RASAL3	1.11e-03	15	62	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	NF1 RASAL3	1.11e-03	15	62	2	PS50018
Domain	RhoGEF	AKAP13 DNMBP FGD6	1.50e-03	68	62	3	SM00325
Domain	RasGAP_dom	NF1 RASAL3	1.60e-03	18	62	2	IPR001936
Domain	RhoGEF	AKAP13 DNMBP FGD6	1.63e-03	70	62	3	PF00621
Domain	DH_2	AKAP13 DNMBP FGD6	1.63e-03	70	62	3	PS50010
Domain	DH-domain	AKAP13 DNMBP FGD6	1.70e-03	71	62	3	IPR000219
Domain	-	AKAP13 DNMBP FGD6	1.70e-03	71	62	3	1.20.900.10
Domain	DS_RBD	DGCR8 SON	2.19e-03	21	62	2	PS50137
Domain	AA-permease/SLC12A_dom	SLC12A3 SLC7A14	2.40e-03	22	62	2	IPR004841
Domain	AA_permease	SLC12A3 SLC7A14	2.40e-03	22	62	2	PF00324
Domain	PH_dom-like	RASAL3 NBEAL2 TLN1 STAP2 AKAP13 FGD6	2.84e-03	426	62	6	IPR011993
Domain	-	DGCR8 SON	3.61e-03	27	62	2	3.30.160.20
Domain	dsRBD_dom	DGCR8 SON	3.88e-03	28	62	2	IPR014720
Pathway	WP_METABOLIC_EPILEPTIC_DISORDERS	ACO1 XDH ENO1 ENO2 ENO3	2.25e-05	91	53	5	M48079
Pathway	KEGG_RNA_DEGRADATION	ENO1 ENO2 ENO3 EXOSC2	6.95e-05	59	53	4	M963
Pathway	KEGG_GLYCOLYSIS_GLUCONEOGENESIS	ALDH3A2 ENO1 ENO2 ENO3	8.45e-05	62	53	4	M11521
Pathway	KEGG_MEDICUS_REFERENCE_GLYCOLYSIS	ENO1 ENO2 ENO3	1.09e-04	25	53	3	M47623
Pathway	REACTOME_GLUCONEOGENESIS	ENO1 ENO2 ENO3	1.23e-04	26	53	3	M13748
Pathway	REACTOME_ALPHA_OXIDATION_OF_PHYTANATE	ALDH3A2 SLC25A17	2.06e-04	6	53	2	M27292
Pathway	REACTOME_ALPHA_OXIDATION_OF_PHYTANATE	ALDH3A2 SLC25A17	2.06e-04	6	53	2	MM14997
Pathway	REACTOME_GLUCOSE_METABOLISM	NUP214 ENO1 ENO2 ENO3	2.88e-04	85	53	4	M1870
Pathway	KEGG_MEDICUS_REFERENCE_CITRATE_CYCLE_FIRST_CARBON_OXIDATION	ACO1 IDH3G	4.91e-04	9	53	2	M47937
Pathway	REACTOME_RETROGRADE_TRANSPORT_AT_THE_TRANS_GOLGI_NETWORK	COG6 NSF VPS54	6.37e-04	45	53	3	MM15355
Pathway	WP_GLYCOLYSIS_AND_GLUCONEOGENESIS	ENO1 ENO2 ENO3	6.37e-04	45	53	3	M39474
Pubmed	A Moonlighting Human Protein Is Involved in Mitochondrial Import of tRNA.	ENO1 ENO2 ENO3	2.49e-08	4	65	3	25918939
Pubmed	Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.	ACO1 IDH3G ALDH3A2 ENO1 ENO2 ENO3	7.66e-08	114	65	6	28245920
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	FMO1 RASAL3 TLN1 AKAP13 NUP214 PRDM4 SUFU TRIP12 SON	1.08e-07	430	65	9	35044719
Pubmed	Cathepsin X cleaves the C-terminal dipeptide of alpha- and gamma-enolase and impairs survival and neuritogenesis of neuronal cells.	ENO1 ENO2 ENO3	1.24e-07	6	65	3	19433310
Pubmed	An analysis of expression patterns of genes encoding proteins with catalytic activities.	ACO1 IDH3G ENO1 ENO2 ENO3	1.72e-07	67	65	5	17626619
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	PCGF6 AKAP9 ACO1 TLN1 ZNF407 ENO1 ENO3 STAG2 SON	3.64e-07	497	65	9	23414517
Pubmed	Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.	ACO1 IDH3G ENO1 ENO2 ENO3	8.92e-07	93	65	5	27215380
Pubmed	Nucleotide sequences of cDNAs alpha and gamma enolase mRNAs from mouse brain.	ENO1 ENO2	3.44e-06	2	65	2	2362815
Pubmed	Peptidylarginine deiminase modulates the physiological roles of enolase via citrullination: links between altered multifunction of enolase and neurodegenerative diseases.	ENO1 ENO2	3.44e-06	2	65	2	22551201
Pubmed	Distribution of serum neuron-specific enolase and the establishment of a population reference interval in healthy adults.	ENO1 ENO2	3.44e-06	2	65	2	30779465
Pubmed	Complete structure of the human gene encoding neuron-specific enolase.	ENO1 ENO2	3.44e-06	2	65	2	2045099
Pubmed	Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism.	GRM5 ITPR3	3.44e-06	2	65	2	22539775
Pubmed	Differential expression of muscle-specific enolase in embryonic and fetal myogenic cells during mouse development.	ENO1 ENO3	3.44e-06	2	65	2	2090519
Pubmed	Isolation of murine neuron-specific and non-neuronal enolase cDNA clones.	ENO1 ENO2	3.44e-06	2	65	2	3801001
Pubmed	Biochemical characterization of the mouse muscle-specific enolase: developmental changes in electrophoretic variants and selective binding to other proteins.	ENO1 ENO3	3.44e-06	2	65	2	9169614
Pubmed	HUPO BPP pilot study: a proteomics analysis of the mouse brain of different developmental stages.	ENO1 ENO2	3.44e-06	2	65	2	17922513
Pubmed	Fibre-type distribution and subcellular localisation of alpha and beta enolase in mouse striated muscle.	ENO1 ENO3	3.44e-06	2	65	2	11229603
Pubmed	Passenger deletions generate therapeutic vulnerabilities in cancer.	ENO1 ENO2	3.44e-06	2	65	2	22895339
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SPG7 PER2 NBEAL2 TLN1 LAMA5 AKAP13 ICE1 NUP214 SUFU DNMBP ITPR3	5.90e-06	1105	65	11	35748872
Pubmed	Borrelia burgdorferi enolase is a surface-exposed plasminogen binding protein.	ENO2 ENO3	1.03e-05	3	65	2	22087329
Pubmed	ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.	ACO1 ENO1	1.03e-05	3	65	2	35121990
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TNIK AKAP9 PER2 TLN1 NUP214 SEZ6L SON	1.11e-05	407	65	7	12693553
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	KATNAL2 NSF TLN1 LAMA5 ANKRD17 ICE1 DGCR8 ALDH3A2 DNMBP EXOSC2 STAG2 SON	1.88e-05	1497	65	12	31527615
Pubmed	Modulation of embryonic and muscle-specific enolase gene products in the developing mouse hindlimb.	ENO1 ENO3	2.06e-05	4	65	2	1280607
Pubmed	Akt-mediated valosin-containing protein 97 phosphorylation regulates its association with ubiquitinated proteins.	NSF ENO1 ENO2	2.44e-05	30	65	3	16027165
Pubmed	USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.	PCGF6 ANKRD17 NUP214 TRIP12	2.52e-05	90	65	4	35654790
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	SLC12A3 ACO1 TLN1 AHSG LAMA5 BPIFB2 POTEJ ENO1 ENO2 ENO3	2.81e-05	1070	65	10	23533145
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NF1 TLN1 ANKRD17 NUP214 TRIP12 STAG2 SON ITPR3	2.91e-05	653	65	8	22586326
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	ZBTB37 PHKA2 PCGF6 ZNF143 NSF ANKRD17 SUFU TRIP12 STAG2	2.99e-05	857	65	9	25609649
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	ANKRD17 AKAP13 ICE1 TRIP12 ITPR3	3.91e-05	202	65	5	33005030
Pubmed	Molecular genetics of successful smoking cessation: convergent genome-wide association study results.	TNIK ITGA11 AKAP13 ALDH3A2	3.96e-05	101	65	4	18519826
Pubmed	Activation of the gene encoding the glycolytic enzyme beta-enolase during early myogenesis precedes an increased expression during fetal muscle development.	ENO1 ENO3	5.13e-05	6	65	2	1525038
Pubmed	Isolation of genes differentially expressed in human primary myoblasts and embryonal rhabdomyosarcoma.	ITGA11 TLN1	5.13e-05	6	65	2	8635876
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TNIK NR2C1 TLN1 ANKRD17 ICE1 NUP214 ALDH3A2 ENO1 SON	5.81e-05	934	65	9	33916271
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	NF1 AKAP13 ICE1 ENO1 TRIP12 SON	5.92e-05	361	65	6	26167880
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	PCGF6 TLN1 ANKRD17 AKAP13 DNMBP TRIP12 EXOSC2 SON	6.02e-05	724	65	8	36232890
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	SNX4 NSF TLN1 ANKRD17 NUP214 ALDH3A2 TRIP12 STAG2 ITPR3	6.20e-05	942	65	9	31073040
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	NR2C1 ZNF143 ICE1 NUP214 DGCR8 ENO1 TRIP12 STAG2 SON	6.83e-05	954	65	9	36373674
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NF1 ANKRD17 NUP214 DNMBP TRIP12 EXOSC2 STAG2 SON	9.57e-05	774	65	8	15302935
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	PDE3A NSF TLN1 ENO1 TRIP12 EXOSC2	1.02e-04	399	65	6	37536630
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	NF1 NSF TLN1 NUP214 ENO1 TRIP12 STAG2 SON ITPR3	1.17e-04	1024	65	9	24711643
Pubmed	Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring.	AKAP9 AKAP13	1.23e-04	9	65	2	12672969
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	NF1 TLN1 AHSG LAMA5 IDH3G ALDH3A2 ENO1 ENO2	1.23e-04	803	65	8	36517590
Pubmed	Comparative mapping of 50 human chromosome 9 loci in the laboratory mouse.	ACO1 NUP214 CTSV	1.37e-04	53	65	3	7774911
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	PCGF6 NSF ENO1 TRIP12 STAG2	1.59e-04	272	65	5	31010829
Pubmed	Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.	POTEJ ENO1 ENO2 ENO3	1.79e-04	149	65	4	22664934
Pubmed	A protein interaction landscape of breast cancer.	NSF ACO1 TLN1 ALDH3A2 ENO1 EXOSC2 ITPR3	1.80e-04	634	65	7	34591612
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	TLN1 AHSG ENO1 EXOSC2 STAG2 SON ITPR3	2.14e-04	652	65	7	31180492
Pubmed	A protein interaction network for the large conductance Ca(2+)-activated K(+) channel in the mouse cochlea.	AHSG ENO1 ENO2 ENO3	2.18e-04	157	65	4	19423573
Pubmed	Genetically engineered mouse models of brain cancer and the promise of preclinical testing.	NF1 SUFU	2.24e-04	12	65	2	19076778
Pubmed	Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.	UGT1A1 FMO1 XDH	2.62e-04	66	65	3	19898482
Pubmed	Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations.	PDE3A AKAP13	2.65e-04	13	65	2	21844884
Pubmed	Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter.	ACO1 CTSV	3.08e-04	14	65	2	2034277
Pubmed	Differential gene expression during early murine yolk sac development.	XDH ENO1	3.08e-04	14	65	2	8562047
Pubmed	Defining the membrane proteome of NK cells.	NF1 RASAL3 NBEAL2 ANKRD17 AKAP13 ENO1 SLC25A17 STAG2 ITPR3	3.11e-04	1168	65	9	19946888
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	KLHL5 TLN1 TRIP12 ENO2 ITPR3	3.46e-04	322	65	5	26514267
Pubmed	Annotation and analysis of 10,000 expressed sequence tags from developing mouse eye and adult retina.	ANKRD17 SON	3.56e-04	15	65	2	14519200
Pubmed	CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.	NSF TLN1 ENO1 EXOSC2	3.83e-04	182	65	4	31067453
Pubmed	Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.	IDH3G ALDH3A2 ENO1 ENO3 SON	3.92e-04	331	65	5	29199018
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	AKAP9 ENO1 SON	3.97e-04	76	65	3	27542412
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	PDE3A TLN1 AKAP13 ENO1	4.50e-04	190	65	4	15161933
Pubmed	Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.	PDE3A TLN1 NUP214 ALDH3A2	4.59e-04	191	65	4	31177093
Pubmed	Docking motif-guided mapping of the interactome of protein phosphatase-1.	VPS54 SLC7A14 ITPR3	4.62e-04	80	65	3	19389623
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	AKAP9 NSF TLN1 ANKRD17 NUP214 ENO1 TRIP12 EXOSC2 ITPR3	5.00e-04	1247	65	9	27684187
Pubmed	Proteomic analysis of NMDA receptor-adhesion protein signaling complexes.	NF1 AKAP9 NSF	5.71e-04	86	65	3	10862698
Pubmed	Proteostasis is essential during cochlear development for neuron survival and hair cell polarity.	NF1 ELP5	5.76e-04	19	65	2	31321879
Pubmed	Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.	ELP5 ACO1 SON	6.31e-04	89	65	3	23891004
Pubmed	Nano-LC based proteomic approach identifies that E6AP interacts with ENO1 and targets it for degradation in breast cancer cells.	ENO1 ENO2	6.39e-04	20	65	2	31329371
Pubmed	BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.	ELP5 TLN1 ANKRD17 DNMBP	7.28e-04	216	65	4	31519766
Pubmed	Proteome analysis of the circadian clock protein PERIOD2.	PER2 TLN1 ENO1	7.40e-04	94	65	3	35122331
Pubmed	Isolation of genes identified in mouse renal proximal tubule by comparing different gene expression profiles.	ACO1 ENO1 CTSV	8.35e-04	98	65	3	9507200
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PCGF6 NF1 TLN1 ANKRD17 AKAP13 NUP214 ENO1 TRIP12 SON	8.94e-04	1353	65	9	29467282
Pubmed	Comparative FISH mapping of mouse and rat homologues of twenty-five human X-linked genes.	PHKA2 IDH3G	9.24e-04	24	65	2	9730605
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ICE1 DNMBP SEZ6L	9.37e-04	102	65	3	10231032
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	KATNAL2 LAMA5 ANKRD17 ALDH3A2 TRIP12 EXOSC2 SON	1.01e-03	847	65	7	35850772
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	TNIK NBEAL2 LAMA5	1.02e-03	105	65	3	9628581
Pubmed	Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach.	ZBTB37 LAMA5 DNMBP	1.05e-03	106	65	3	18654987
Pubmed	Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.	TLN1 ANKRD17 ENO1	1.08e-03	107	65	3	30995489
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NF1 AKAP9 ANKRD17 AKAP13 DNMBP TRIP12 FGD6	1.11e-03	861	65	7	36931259
Pubmed	Study of FOXO1-interacting proteins using TurboID-based proximity labeling technology.	TLN1 AHSG ENO1 ENO3	1.13e-03	243	65	4	36964488
Pubmed	Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.	ZNF143 NUP214 SON	1.17e-03	110	65	3	26841866
Pubmed	5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.	NF1 NSF	1.17e-03	27	65	2	23027611
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	NSF TLN1 NUP214 ALDH3A2 STAG2 SON	1.23e-03	638	65	6	33239621
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ZNF143 NF1 ANKRD17 POTEJ STAG2 ITPR3	1.23e-03	638	65	6	31182584
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	LAMA5 NUP214 TRIP12 SON	1.25e-03	250	65	4	33536335
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	AKAP13 ENO1 FGD6 SON	1.35e-03	255	65	4	15324660
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PHKA2 ZNF143 ANKRD17 AKAP13 SLC25A17 DDX11L8	1.35e-03	650	65	6	38777146
Pubmed	Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis.	ENO1 ENO2 ENO3	1.36e-03	116	65	3	37117180
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	PHKA2 PER2 TLN1 AHSG XDH NUP214 ALDH3A2 STAG2	1.36e-03	1155	65	8	20360068
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	NF1 ANKRD17 NUP214 TRIP12 ITPR3	1.40e-03	440	65	5	34244565
Pubmed	Comparative mapping of the human 22q11 chromosomal region and the orthologous region in mice reveals complex changes in gene organization.	NF1 DGCR8	1.45e-03	30	65	2	9405660
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	TNIK SNX4 AKAP9	1.50e-03	120	65	3	31413325
Pubmed	Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes.	ENO1 ENO2 ENO3	1.53e-03	121	65	3	8827514
Pubmed	BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.	NUP214 DGCR8	1.54e-03	31	65	2	23086144
Pubmed	A mouse knockout library for secreted and transmembrane proteins.	NBEAL2 C1QTNF6 LNX1 CTSV SEZ6L	1.71e-03	460	65	5	20562862
Pubmed	LZTR1 is a regulator of RAS ubiquitination and signaling.	TNIK NF1 NSF	1.76e-03	127	65	3	30442766
Interaction	BICD2 interactions	TNIK SNX4 AKAP9 COG6 TLN1 SUFU DNMBP LNX1 EXOSC2	7.62e-06	426	64	9	int:BICD2
Interaction	GRIN1 interactions	TNIK NF1 AKAP9 NSF GRM5 LNX1	9.39e-06	154	64	6	int:GRIN1
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	AKAP9 VPS54 GRM5 SLC7A14 ITPR3	9.35e-05	181	46	5	694
GeneFamily	AAA ATPases	KATNAL2 SPG7 NSF	3.30e-04	53	46	3	413
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	AKAP13 DNMBP FGD6	6.30e-04	66	46	3	722
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	AKAP9 AKAP13	2.46e-03	29	46	2	396
Coexpression	WANG_LMO4_TARGETS_DN	PCGF6 PDE3A SNX4 AKAP9 COG6 ZNF407 DGCR8 TRIP12	2.71e-06	361	64	8	M12674
Coexpression	GSE42724_MEMORY_BCELL_VS_PLASMABLAST_UP	AKAP9 ELP5 STAP2 VPS54 PRDM4 ENO2	9.23e-06	199	64	6	M9786
Coexpression	GSE4142_PLASMA_CELL_VS_GC_BCELL_UP	PDE3A RASAL3 SPG7 AHSG BPIFB2 PRDM4	9.50e-06	200	64	6	M6390
Coexpression	MOOTHA_GLYCOLYSIS	ENO1 ENO2 ENO3	1.79e-05	21	64	3	M16111
Coexpression	ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM	AHSG ENO1 CX3CL1 CTSV	2.21e-05	67	64	4	M1686
Coexpression	ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM	AHSG ENO1 CX3CL1 CTSV	2.78e-05	71	64	4	MM1210
Coexpression	HALLMARK_FATTY_ACID_METABOLISM	FMO1 IDH3G ALDH3A2 ENO2 ENO3	4.27e-05	158	64	5	M5935
Coexpression	MOOTHA_GLUCONEOGENESIS	ENO1 ENO2 ENO3	5.94e-05	31	64	3	M13448
Coexpression	GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN	PCGF6 TLN1 AKAP13 NUP214 ITPR3	8.80e-05	184	64	5	M19988
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA11 CHCHD10 FMO1 SLC12A3 FGD6	7.14e-06	183	65	5	bc24145855bf4d027a8058bf92bc796c10f241bb
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA11 CHCHD10 FMO1 SLC12A3 FGD6	7.14e-06	183	65	5	4c325ee6da070513097a11445ec95b0415ffd8a2
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLHL5 SNX4 AKAP9 TLN1 SON	8.57e-06	190	65	5	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-MGE2\|World / Primary Cells by Cluster	KLHL5 PDE3A AKAP9 GRM5 SLC7A14	9.48e-06	194	65	5	b42fd64b0fb95434a9e4e6586f31d26114a4074b
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-MGE2-10\|World / Primary Cells by Cluster	KLHL5 PDE3A AKAP9 GRM5 SLC7A14	9.48e-06	194	65	5	81e7bc6516ab8d02ccd1c76a56a3533b788c27c8
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL5 PDE3A FMO1 XDH CX3CL1	9.48e-06	194	65	5	f159ef8541d75a4e98468947f231bb463bec922c
ToppCell	Bronchial_Biopsy\|World / Tissue, Lineage and Cell class of Lung Cells from 10X	AKAP9 PER2 LAMA5 ALDH3A2 CX3CL1	1.05e-05	198	65	5	f5b7013045b61fc56894f80092f799770dde1c8f
Computational	Glycolysis and TCA cycle.	ACO1 IDH3G ENO1 ENO2	3.75e-06	26	45	4	MODULE_306
Drug	N-succinylphenylglycine	ENO1 ENO2 ENO3	2.02e-08	3	63	3	CID000448582
Drug	AC1MOUJL	ENO1 ENO2 ENO3	2.02e-08	3	63	3	CID003400924
Drug	C03356	ENO1 ENO2 ENO3	2.02e-08	3	63	3	CID000439988
Drug	3-bromo-2-(bromomethyl)propionic acid	ENO1 ENO2 ENO3	2.02e-08	3	63	3	CID000318915
Drug	C04309	ENO1 ENO2 ENO3	2.02e-08	3	63	3	CID000440293
Drug	2,3-diketo-1-phosphohexane	ENO1 ENO2 ENO3	2.02e-08	3	63	3	CID000192519
Drug	AC1L18ZV	SLC12A3 ENO1 ENO2 ENO3	2.59e-08	12	63	4	CID000000329
Drug	dimethyl chlorophosphate	ENO1 ENO2 ENO3	8.06e-08	4	63	3	CID000101863
Drug	[2-(oxidoamino)-2-oxoethyl]phosphonic acid	ENO1 ENO2 ENO3	8.06e-08	4	63	3	CID011969443
Drug	3-aminoenolpyruvate-2-phosphate	ENO1 ENO2 ENO3	8.06e-08	4	63	3	CID003037152
Drug	2-ptz	ENO1 ENO2 ENO3	8.06e-08	4	63	3	CID000445375
Drug	tricyclohexylammonium	ENO1 ENO2 ENO3	8.06e-08	4	63	3	CID000226271
Drug	N-methylacrylamide	ENO1 ENO2 ENO3	2.01e-07	5	63	3	CID000014471
Drug	AC1L1CAI	ENO1 ENO2 ENO3	2.01e-07	5	63	3	CID000000145
Drug	tartronate semialdehyde phosphate	ENO1 ENO2 ENO3	2.01e-07	5	63	3	CID000151938
Drug	2-phospho-3-butenoic acid	ENO1 ENO2 ENO3	2.01e-07	5	63	3	CID000191423
Drug	1-Pdmsp	ENO1 ENO2 ENO3	2.01e-07	5	63	3	CID000000561
Drug	dimidium	ENO1 ENO2 ENO3	4.01e-07	6	63	3	CID000068207
Drug	Z(2-Cl)-OSu	ENO1 ENO2 ENO3	4.01e-07	6	63	3	CID000580665
Drug	4-(N,N-dimethylamino)cinnamoyl-CoA	ENO1 ENO2 ENO3	4.01e-07	6	63	3	CID000445461
Drug	N-tert-butylacrylamide	ENO1 ENO2 ENO3	7.01e-07	7	63	3	CID000007877
Drug	glycidol phosphate	ENO1 ENO2 ENO3	7.01e-07	7	63	3	CID000152659
Drug	lavendustin C6	ENO1 ENO2 ENO3	7.01e-07	7	63	3	CID000126839
Drug	CPEP	ENO1 ENO2 ENO3	7.01e-07	7	63	3	CID000360637
Drug	macrophomate	ENO1 ENO2 ENO3	1.12e-06	8	63	3	CID010889109
Drug	quercetin dihydrate; Up 200; 1uM; MCF7; HG-U133A	PHKA2 SPG7 NBEAL2 IDH3G PRDM4 CTSV ITPR3	1.16e-06	196	63	7	283_UP
Drug	1-phenylpentan-3-amine	ENO1 ENO2 ENO3 CTSV	1.20e-06	29	63	4	CID005195771
Drug	manganese	PHKA2 ITGA11 NSF ACO1 LAMA5 NUP214 IDH3G ALDH3A2 ENO1 ENO2 ENO3 ITPR3	1.49e-06	791	63	12	CID000023930
Drug	AC1L19IJ	ENO1 ENO2 ENO3	1.68e-06	9	63	3	CID000000562
Drug	AC1L1A4W	ENO1 ENO2 ENO3	1.68e-06	9	63	3	CID000000837
Drug	AC1Q5BXE	ALDH3A2 ENO1 ENO2 ENO3	1.81e-06	32	63	4	CID000000037
Drug	magnesium	PHKA2 ITGA11 ZNF143 NF1 SPG7 SLC12A3 NSF LAMA5 NUP214 IDH3G ALDH3A2 GRM5 ENO1 ENO2 ENO3	2.38e-06	1325	63	15	CID000000888
Drug	pyrene-4,5-dione	ENO1 ENO2 ENO3	2.39e-06	10	63	3	CID000160814
Drug	L-fuconic acid	ENO1 ENO2 ENO3	2.39e-06	10	63	3	CID000345732
Drug	phosphoenolthiopyruvate	ENO1 ENO2 ENO3	2.39e-06	10	63	3	CID000194910
Drug	xylonate	ENO1 ENO2 ENO3	2.39e-06	10	63	3	CID000010264
Drug	LG61	ENO1 ENO2 ENO3	4.36e-06	12	63	3	CID000520177
Drug	B-43	ENO1 ENO2 ENO3	7.19e-06	14	63	3	CID006603792
Drug	Hecameg	ENO1 ENO2 ENO3	7.19e-06	14	63	3	CID002733955
Drug	pipemidic acid	ENO1 ENO2 ENO3	8.97e-06	15	63	3	CID000004831
Drug	1 IN	ENO1 ENO2 ENO3	8.97e-06	15	63	3	CID000449311
Drug	Freon 22	ENO1 ENO2 ENO3	1.10e-05	16	63	3	CID000006372
Drug	2-PE	ENO1 ENO2 ENO3	1.34e-05	17	63	3	CID000004867
Drug	N,N-Dichlorourethane	ENO1 ENO2 ENO3	1.60e-05	18	63	3	CID000026195
Drug	o-succinylbenzoic acid	ENO1 ENO2 ENO3	1.60e-05	18	63	3	CID000000955
Drug	AC1L1A7Z	ENO1 ENO2 ENO3	1.60e-05	18	63	3	CID000000874
Drug	Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; PC3; HG-U133A	AKAP13 IDH3G FGD6 EXOSC2 SEZ6L ITPR3	1.70e-05	196	63	6	1912_UP
Drug	LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A	SPG7 NBEAL2 LAMA5 FGD6 ENO2 ITPR3	1.80e-05	198	63	6	6976_UP
Drug	Drofenine hydrochloride [548-66-3]; Up 200; 11.4uM; HL60; HT_HG-U133A	TNIK C16orf95 AHSG XDH ZNF407 ITPR3	1.80e-05	198	63	6	2714_UP
Drug	oxaloacetate	PHKA2 ACO1 IDH3G ENO1 ENO2 ENO3	1.80e-05	198	63	6	CID000000970
Drug	Mefenamic acid [61-68-7]; Up 200; 16.6uM; HL60; HT_HG-U133A	PHKA2 NF1 AKAP9 SPG7 ALDH3A2 ENO2	1.86e-05	199	63	6	1863_UP
Drug	3-aminobenzamide; Down 200; 10000uM; MCF7; HG-U133A	ZNF143 NF1 SLC12A3 IDH3G PRDM4 SEZ6L	1.86e-05	199	63	6	590_DN
Drug	purpurin-18	ENO1 ENO2 ENO3	1.90e-05	19	63	3	CID005489047
Drug	AC1L2YVP	ENO1 ENO2 ENO3	1.90e-05	19	63	3	CID000080135
Drug	histidinol phosphate	ENO1 ENO2 ENO3	1.90e-05	19	63	3	CID000000845
Drug	chlorpropamide; Down 200; 100uM; MCF7; HG-U133A	AKAP9 NUP214 DGCR8 IDH3G CTSV SLC25A17	1.91e-05	200	63	6	141_DN
Drug	enoxacin	ENO1 ENO2 ENO3	2.23e-05	20	63	3	CID000003229
Drug	dodecanol	ZNF143 DGCR8 ALDH3A2	2.23e-05	20	63	3	CID000008193
Drug	LG 5	LAMA5 ENO1 ENO2 ENO3	2.31e-05	60	63	4	CID011840957
Drug	Acth(11-24)	ENO1 ENO2 ENO3	2.99e-05	22	63	3	CID003037130
Drug	hydroxymalonate	ENO1 ENO2 ENO3	3.44e-05	23	63	3	CID000000044
Drug	pefloxacin	ENO1 ENO2 ENO3	5.02e-05	26	63	3	CID000051081
Drug	6-[4-[(4-ethyl-2,3-dihydropyrazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine	ENO1 ENO2 ENO3	5.02e-05	26	63	3	CID016040258
Drug	Fenofibrate	UGT1A1 FMO1 ACO1 DNMBP LNX1 ENO1 TRIP12 CX3CL1 SON	5.21e-05	624	63	9	ctd:D011345
Drug	theobromine	FMO1 XDH NUP214	7.01e-05	29	63	3	CID000005429
Drug	Glu-Ala	ENO1 ENO2 ENO3	7.01e-05	29	63	3	CID000100098
Drug	tetrahydroaldosterone-3-glucuronide	ENO1 ENO2 ENO3	7.01e-05	29	63	3	CID000167918
Drug	acamprosate	PER2 GRM5	7.50e-05	5	63	2	ctd:C043877
Drug	Sa-6	AHSG STAG2	7.50e-05	5	63	2	CID000056560
Drug	reductone	ENO1 ENO2 ENO3	7.77e-05	30	63	3	CID003034155
Drug	m1 C	ENO1 ENO2 ENO3	9.46e-05	32	63	3	CID000448219
Drug	Thimerosal	CHCHD10 SNX4 NF1 AKAP9 ALDH3A2 ENO1 FGD6 ENO2 ENO3 STAG2 SON ITPR3	9.48e-05	1199	63	12	ctd:D013849
Drug	autoinducer-2	ENO1 ENO2 ENO3	1.04e-04	33	63	3	CID000446576
Drug	mucic acid	ALDH3A2 ENO1 ENO2 ENO3	1.04e-04	88	63	4	CID000000607
Drug	9-nitroanthracene	AHSG XDH	1.12e-04	6	63	2	CID000011767
Drug	phosphoglycolate	ENO1 ENO2 ENO3 ITPR3	1.14e-04	90	63	4	CID000000529
Drug	aldonates	ALDH3A2 ENO1 ENO2 ENO3	1.14e-04	90	63	4	CID000000752
Drug	2-phosphoglycerate	ALDH3A2 ENO1 ENO2 ENO3	1.35e-04	94	63	4	CID000000059
Drug	N-acetylserine	ENO1 ENO2 ENO3	1.35e-04	36	63	3	CID000065249
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HG-U133A	VPS54 DGCR8 IDH3G STAG2 SON	1.49e-04	182	63	5	1891_DN
Drug	pyruvic acid	PHKA2 ACO1 IDH3G ALDH3A2 ENO1 ENO2 ENO3	1.67e-04	424	63	7	CID000001060
Drug	n-octylamine	FMO1 XDH NUP214	1.72e-04	39	63	3	CID000008143
Drug	ciprofloxacin	NF1 ENO1 ENO2 ENO3	1.78e-04	101	63	4	CID000002764
Drug	troglitazone; Down 200; 10uM; HL60; HT_HG-U133A	NF1 AKAP13 ENO2 EXOSC2 ITPR3	1.78e-04	189	63	5	2692_DN
Drug	Securinine [5610-40-2]; Up 200; 18.4uM; HL60; HT_HG-U133A	NF1 C16orf95 ZNF407 NUP214 ITPR3	1.78e-04	189	63	5	2729_UP
Drug	AMP group	PHKA2 PDE3A IDH3G ALDH3A2 ENO1 ENO2 ENO3 SLC25A17	1.89e-04	579	63	8	CID000000224
Drug	phthalocyaninetetrasulfonic acid	ENO1 ENO2 ENO3	2.00e-04	41	63	3	CID005742784
Drug	Hexestrol [84-16-2]; Down 200; 14.8uM; HL60; HT_HG-U133A	NR2C1 ACO1 NBEAL2 IDH3G ENO2	2.01e-04	194	63	5	2515_DN
Drug	5666823; Down 200; 100uM; MCF7; HG-U133A	ZNF143 NBEAL2 XDH SEZ6L ITPR3	2.06e-04	195	63	5	609_DN
Drug	Tiletamine hydrochloride; Down 200; 15.4uM; HL60; HT_HG-U133A	TNIK NR2C1 DGCR8 IDH3G DNMBP	2.06e-04	195	63	5	3137_DN
Drug	Asiaticoside [16830-15-2]; Down 200; 4.2uM; MCF7; HT_HG-U133A	NF1 C16orf95 NBEAL2 DNMBP SLC25A17	2.06e-04	195	63	5	3504_DN
Drug	bis(tri-n-hexylsiloxy) silicon phthalocyanine	ENO3 EXOSC2	2.09e-04	8	63	2	CID000163602
Drug	C04226	ACO1 XDH	2.09e-04	8	63	2	CID000151255
Drug	citrazinic acid	ACO1 IDH3G	2.09e-04	8	63	2	CID000007425
Drug	3-methylitaconate	ACO1 XDH	2.09e-04	8	63	2	CID006438940
Drug	Niflumic acid [4394-00-7]; Down 200; 14.2uM; MCF7; HT_HG-U133A	AKAP9 C16orf95 ALDH3A2 FGD6 CTSV	2.11e-04	196	63	5	7430_DN
Drug	Azathymine, 6 [932-53-6]; Down 200; 31.4uM; MCF7; HT_HG-U133A	PHKA2 NF1 C16orf95 TLN1 AKAP13	2.11e-04	196	63	5	2827_DN
Drug	Morantel tartrate [26155-31-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A	NF1 AKAP9 C16orf95 TLN1 CTSV	2.11e-04	196	63	5	7010_UP
Drug	alpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A	C16orf95 LAMA5 XDH NUP214 ITPR3	2.11e-04	196	63	5	6169_UP
Drug	Sulpiride [15676-16-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	NR2C1 NF1 AHSG AKAP13 NUP214	2.16e-04	197	63	5	1467_UP
Disease	corpus callosum volume measurement	TNIK C16orf95 TLN1 LNX1	6.75e-05	100	64	4	EFO_0010299
Disease	Cocaine Dependence	KLHL5 PER2 NSF GRM5	2.41e-04	139	64	4	C0600427
Disease	triacylglycerol 58:12 measurement	LNX1 TRIP12	3.01e-04	12	64	2	EFO_0010439
Disease	motor neuron disease (implicated_via_orthology)	CHCHD10 VPS54	3.01e-04	12	64	2	DOID:231 (implicated_via_orthology)
Disease	Glycogen storage disease	PHKA2 ENO3	6.17e-04	17	64	2	cv:C0017919
Disease	sensorineural hearing loss (implicated_via_orthology)	LNX1 SLC7A14	7.73e-04	19	64	2	DOID:10003 (implicated_via_orthology)
Disease	Uterine leiomyoma	ITGA11 COG6 LNX1	1.03e-03	91	64	3	HP_0000131
Disease	portal hypertension (biomarker_via_orthology)	XDH CX3CL1	1.04e-03	22	64	2	DOID:10762 (biomarker_via_orthology)
Disease	Ischemic stroke, coronary artery disease	RASAL3 NSF FGD6	1.06e-03	92	64	3	EFO_0001645, HP_0002140
Disease	major depressive disorder, COVID-19	NSF GRM5	1.46e-03	26	64	2	MONDO_0002009, MONDO_0100096
Disease	Glycogen Storage Disease	PHKA2 ENO3	1.57e-03	27	64	2	C0017919
Disease	corpus callosum mid-anterior volume measurement	C16orf95 LNX1	1.57e-03	27	64	2	EFO_0010297
Disease	corpus callosum central volume measurement	C16orf95 LNX1	1.69e-03	28	64	2	EFO_0010296
Disease	hyperthyroidism (biomarker_via_orthology)	UGT1A1 CTSV	1.69e-03	28	64	2	DOID:7998 (biomarker_via_orthology)
Disease	hair colour measurement	TNIK SPG7 AKAP13 BPIFB2 GRM5 LNX1	2.15e-03	615	64	6	EFO_0007822

Protein segments in the cluster

Peptide	Gene	Start	Entry
LVGTDSHTTMIDGLG	ACO1	201	P21399
DGVVTMTSRGAEGSV	AKAP9	1021	Q99996
ATVGPISVAMDAGHS	CTSV	241	O60911
TNVSTPDTAGEMEHG	AKAP13	471	Q12802
DETSSGGVTGNDVIM	ALDH3A2	376	P51648
GLVMEAATHSQGDGS	DNMBP	531	Q6XZF7
DGSTMLIEAAKGGHT	ANKRD17	696	O75179
QTSSGAEVMDVGSGG	DGCR8	41	Q8WYQ5
GVMVSHRSGETEDTF	ENO2	366	P09104
RVGSASSEGSIHVAM	RASAL3	161	Q86YV0
SSVAGMEGSVHLITG	NR2C1	341	P13056
GHEVSERVQSSEMGT	ITPR3	1851	Q14573
AFTTSTVVRMHVGDG	GRM5	836	P41594
HEMVETGGSEGVVRS	CD300H	66	A0A0K2S4Q6
AMGTTGATETAAVGA	PER2	1006	O15055
VHAVAGAVGSVTAMT	SLC25A17	11	O43808
MAGTTGGVDAATTGA	MUC19	1731	Q7Z5P9
TDVGVATGVGMATGI	MUC19	8001	Q7Z5P9
ESVMSQRGTASGGEH	KATNAL2	356	Q8IYT4
TSITVDIAVMGEAHG	PDE3A	341	Q14432
ESLGMTVAGGASHRE	LNX1	516	Q8TBB1
VHGSSPGVMGTSVAT	NUP214	1041	P35658
QRGSMAGSTGVHDTV	NSF	336	P46459
MSQTGFSSHVVEDGV	ITGA11	366	Q9UKX5
AMTRSVEVHGAVGAS	LAMA5	3676	O15230
DTITTDTGFMRGHGT	EXOSC2	31	Q13868
AVGGMDSTKGATSIE	KLHL5	471	Q96PQ7
MAEGSGEVVAVSATG	COG6	1	Q9Y2V7
GVMVSHRSGETEDTF	ENO1	366	P06733
MHTPDIGGQGTTSEA	IDH3G	361	P51553
GTHGSEMLPATEVTV	ICE1	996	Q9Y2F5
GEATGHRVTMGTAAL	C1QTNF6	11	Q9BXI9
MGVVSLGSPSGEVSH	AHSG	321	P02765
TAAGVAVGSAVGHVM	CHCHD10	51	Q8WYQ3
AVGSAVGHVMGSALT	CHCHD10	56	Q8WYQ3
GMGNSGTDIAVEASH	FMO1	191	Q01740
IDTITGMHSVEVSGS	DDX11L8	401	A8MPP1
HAAGTTAGGSAVMSA	C16orf95	116	Q9H693
GVMVSHRSGETEDTF	ENO3	366	P13929
TEVTLGGTMGQASAH	ELP5	186	Q8TE02
SDTEMTSIGGIIHVD	PHKA2	1151	P46019
VAMGTGHVDVSSDSL	PRDM4	336	Q9UKN5
MEGVAVVTAGSVGAA	PCGF6	1	Q9BYE7
EGAGEESSGVDTMTH	SNX4	36	O95219
GDGADGVSVTTRQMH	STAP2	181	Q9UGK3
SGDVTVMDLHSGGVA	SEZ6L	401	Q9BYH1
DMAVSGSEDGTVIIH	NBEAL2	2566	Q6ZNJ1
TTGIVMDSGDGVTHT	POTEJ	811	P0CG39
DGMGTTDHVIVLAST	SPG7	441	Q9UQ90
RHVGTEGSMATVGLS	BPIFB2	246	Q8N4F0
PVESMLEGTGTTTAH	SLC7A14	31	Q8TBB6
GLGRVSTHSQEMDSG	TNIK	946	Q9UKE5
VSIDGSESVAGTGMI	ZNF143	191	P52747
GTHSVAMVTAEGTEG	ZNF143	546	P52747
VTAMVIDTTGHGSVG	ZBTB37	271	Q5TC79
GGDDDTMSVISGISS	STAG2	1051	Q8N3U4
EAASAAGVVGGMVDS	TLN1	1816	Q9Y490
VDGSSMSLAVDEGTG	FGD6	431	Q6ZV73
TGDMAITFVSTGVEG	SUFU	401	Q9UMX1
ASGEHGIVVFSLGSM	UGT1A1	296	P22309
RMSHVSGGGSIDLSD	NF1	816	P21359
HEMTDGLVEGEAGTS	SLC12A3	111	P55017
TDGSVLLTHGGTEMG	XDH	1026	P47989
DGAASMTGKHSEVVT	ZBED9	971	Q6R2W3
MELGHGAGTTTFTRA	TEX33	1	O43247
VVSEEGAVHMVAGEG	ZNF407	2106	Q9C0G0
AGAVGMTTSGESESD	TRIP12	381	Q14669
DTEHDMVISTSPSGG	SON	1636	P18583
GSMAHVSVVPVSSEG	CX3CL1	281	P78423
EHTSSSAIPGGVDIM	VPS54	566	Q9P1Q0