Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

RGPD4 RANBP2 RGPD3 PPIL4 FKBP14

3.04e-0750575GO:0003755
GeneOntologyMolecularFunctioncis-trans isomerase activity

RGPD4 RANBP2 RGPD3 PPIL4 FKBP14

4.09e-0753575GO:0016859
GeneOntologyMolecularFunctionphosphatidylinositol-5-phosphate binding

WASHC2C TOM1 PLA2G4A WASHC2A

5.07e-0723574GO:0010314
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RANBP2 RGPD3

2.43e-0520573GO:0061665
GeneOntologyMolecularFunctionGTPase activator activity

RGPD4 ARHGDIB RANBP2 FAM13A RASA3 RGPD3

1.41e-04279576GO:0005096
GeneOntologyMolecularFunctionphosphatidylinositol-4-phosphate binding

WASHC2C PLA2G4A WASHC2A

1.47e-0436573GO:0070273
GeneOntologyMolecularFunctionSUMO transferase activity

RGPD4 RANBP2 RGPD3

1.47e-0436573GO:0019789
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

CECR2 HLTF CHD7

1.60e-0437573GO:0140658
GeneOntologyMolecularFunctionisomerase activity

RGPD4 RANBP2 RGPD3 PPIL4 FKBP14

2.18e-04192575GO:0016853
GeneOntologyMolecularFunctionphosphatidylinositol binding

WASHC2C ESYT1 TOM1 PLA2G4A WASHC2A RPS6KC1

2.76e-04316576GO:0035091
GeneOntologyMolecularFunctionphosphatidylinositol-3-phosphate binding

WASHC2C PLA2G4A WASHC2A

3.48e-0448573GO:0032266
GeneOntologyMolecularFunctionretromer complex binding

WASHC2C WASHC2A

3.55e-0410572GO:1905394
GeneOntologyMolecularFunctionsmall GTPase binding

RGPD4 ARHGDIB RANBP2 INF2 RGPD3

2.20e-03321575GO:0031267
GeneOntologyMolecularFunctionphosphatidylinositol phosphate binding

WASHC2C TOM1 PLA2G4A WASHC2A

2.50e-03199574GO:1901981
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RGPD4 ARHGDIB RANBP2 FAM13A RASA3 RGPD3

3.16e-03507576GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RGPD4 ARHGDIB RANBP2 FAM13A RASA3 RGPD3

3.16e-03507576GO:0030695
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate binding

WASHC2C WASHC2A

3.53e-0331572GO:0080025
GeneOntologyMolecularFunctionGTPase binding

RGPD4 ARHGDIB RANBP2 INF2 RGPD3

3.60e-03360575GO:0051020
GeneOntologyMolecularFunctionphosphatidylinositol-3,4-bisphosphate binding

WASHC2C WASHC2A

4.48e-0335572GO:0043325
GeneOntologyMolecularFunctionphospholipid binding

WASHC2C ESYT1 TOM1 PLA2G4A WASHC2A RPS6KC1

4.61e-03548576GO:0005543
GeneOntologyMolecularFunctioncalcium ion binding

CCDC47 CETN3 ESYT1 SPTA1 PLA2G4A PLCH1 FKBP14

5.26e-03749577GO:0005509
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

RGPD4 RANBP2 UBE3B RGPD3 HLTF

5.49e-03398575GO:0061659
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

CECR2 HLTF CHD7

5.72e-03127573GO:0008094
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RANBP2 RGPD3

1.57e-069563GO:0033133
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD4 RANBP2 RGPD3

2.24e-0610563GO:1903301
GeneOntologyBiologicalProcessprotein peptidyl-prolyl isomerization

RGPD4 RANBP2 RGPD3 PPIL4

3.36e-0638564GO:0000413
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD4 RANBP2 RGPD3

5.32e-0613563GO:0033131
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD4 RANBP2 RGPD3

6.76e-0614563GO:1903299
GeneOntologyBiologicalProcesspeptidyl-proline modification

RGPD4 RANBP2 RGPD3 PPIL4

1.39e-0554564GO:0018208
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD4 RANBP2 RGPD3

2.09e-0520563GO:0006607
GeneOntologyBiologicalProcessprotein folding

RGPD4 RANBP2 CCDC47 RGPD3 PDCL2 DNAJC2

5.34e-05246566GO:0006457
GeneOntologyBiologicalProcessprotein localization to endosome

WASHC2C LRRC7 WASHC2A

9.76e-0533563GO:0036010
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD4 RANBP2 CETN3 RGPD3

1.48e-0718574GO:0044615
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RANBP2 RGPD3

1.07e-068573GO:1990723
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RANBP2 RGPD3

2.28e-0610573GO:0044614
GeneOntologyCellularComponentannulate lamellae

RGPD4 RANBP2 RGPD3

6.85e-0614573GO:0005642
GeneOntologyCellularComponentnuclear inclusion body

RGPD4 RANBP2 RGPD3

2.12e-0520573GO:0042405
GeneOntologyCellularComponentSUMO ligase complex

RGPD4 RANBP2 RGPD3

2.47e-0521573GO:0106068
GeneOntologyCellularComponentnuclear pore

RGPD4 RANBP2 CETN3 RGPD3

1.67e-04101574GO:0005643
GeneOntologyCellularComponentWASH complex

WASHC2C WASHC2A

7.50e-0415572GO:0071203
GeneOntologyCellularComponentinclusion body

RGPD4 RANBP2 RGPD3

1.91e-0390573GO:0016234
MousePhenoimpaired glucose tolerance

RGPD4 RANBP2 FAM13A RGPD3 PLA2G4A COL14A1 CPE ODAD3 CCDC116

1.23e-05480439MP:0005293
MousePhenoelevated level of mitotic sister chromatid exchange

RGPD4 RANBP2 RGPD3

1.48e-0516433MP:0003701
MousePhenoabnormal morula morphology

RGPD4 RANBP2 RGPD3

6.71e-0526433MP:0012058
MousePhenodecreased tumor latency

RGPD4 RANBP2 RGPD3

1.04e-0430433MP:0010308
MousePhenoabnormal glucose tolerance

RGPD4 RANBP2 FAM13A RGPD3 PLA2G4A COL14A1 CPE CHD7 ODAD3 CCDC116

1.06e-047874310MP:0005291
MousePhenofailure of blastocyst formation

RGPD4 RANBP2 RGPD3

1.15e-0431433MP:0012129
MousePhenoabnormal tumor latency

RGPD4 RANBP2 RGPD3

1.52e-0434433MP:0010307
MousePhenoabnormal blastocyst formation

RGPD4 RANBP2 RGPD3

2.29e-0439433MP:0012128
MousePhenoabnormal spatial reference memory

SUPT16H LRRC7 DDHD2 DNMT1

3.18e-04107434MP:0008414
MousePhenodecreased neuronal stem cell self-renewal

SUPT16H DNMT1

3.28e-049432MP:0012207
DomainRan_BP1

RGPD4 RANBP2 RGPD3

5.81e-0612573PF00638
DomainRANBD1

RGPD4 RANBP2 RGPD3

5.81e-0612573PS50196
DomainRanBD

RGPD4 RANBP2 RGPD3

7.54e-0613573SM00160
DomainRan_bind_dom

RGPD4 RANBP2 RGPD3

7.54e-0613573IPR000156
DomainFAM21

WASHC2C WASHC2A

9.15e-062572IPR027308
DomainFAM21/CAPZIP

WASHC2C WASHC2A

2.74e-053572IPR029341
DomainCAP-ZIP_m

WASHC2C WASHC2A

2.74e-053572PF15255
DomainGCC2_Rab_bind

RGPD4 RGPD3

1.90e-047572IPR032023
DomainRab_bind

RGPD4 RGPD3

1.90e-047572PF16704
Domain-

RGPD4 RGPD3

4.05e-04105721.10.220.60
DomainGrip

RGPD4 RGPD3

4.94e-0411572SM00755
DomainGRIP

RGPD4 RGPD3

4.94e-0411572PF01465
DomainGRIP_dom

RGPD4 RGPD3

5.92e-0412572IPR000237
DomainGRIP

RGPD4 RGPD3

5.92e-0412572PS50913
DomainC2

RASA3 ESYT1 PLA2G4A PLCH1

6.85e-04131574PF00168
DomainC2

RASA3 ESYT1 PLA2G4A PLCH1

8.10e-04137574SM00239
DomainC2

RASA3 ESYT1 PLA2G4A PLCH1

9.26e-04142574PS50004
Domain-

RASA3 ESYT1 PLA2G4A PLCH1

1.08e-031485742.60.40.150
DomainEFh

CETN3 SPTA1 PLCH1 FKBP14

1.37e-03158574SM00054
DomainC2_dom

RASA3 ESYT1 PLA2G4A PLCH1

1.58e-03164574IPR000008
Domainzf-RanBP

RANBP2 ZRANB2

2.03e-0322572PF00641
DomainCyclophilin-like_dom

RANBP2 PPIL4

2.03e-0322572IPR029000
DomainCSA_PPIASE_2

RANBP2 PPIL4

2.03e-0322572PS50072
DomainPro_isomerase

RANBP2 PPIL4

2.03e-0322572PF00160
Domain-

RANBP2 PPIL4

2.03e-03225722.40.100.10
DomainCyclophilin-type_PPIase_dom

RANBP2 PPIL4

2.03e-0322572IPR002130
DomainCSA_PPIASE_1

RANBP2 PPIL4

2.03e-0322572PS00170
DomainZnF_RBZ

RANBP2 ZRANB2

2.22e-0323572SM00547
DomainZF_RANBP2_2

RANBP2 ZRANB2

2.22e-0323572PS50199
DomainZF_RANBP2_1

RANBP2 ZRANB2

2.42e-0324572PS01358
DomainZnf_RanBP2

RANBP2 ZRANB2

2.62e-0325572IPR001876
DomainSNF2_N

HLTF CHD7

4.28e-0332572IPR000330
DomainSNF2_N

HLTF CHD7

4.28e-0332572PF00176
DomainEF_HAND_2

CETN3 SPTA1 PLCH1 FKBP14

5.39e-03231574PS50222
DomainEF_hand_dom

CETN3 SPTA1 PLCH1 FKBP14

5.48e-03232574IPR002048
Domain-

RGPD4 RANBP2 RASA3 RGPD3 PLCH1

6.73e-033915752.30.29.30
DomainTPR

RGPD4 RANBP2 RGPD3

7.18e-03129573SM00028
DomainTPR_repeat

RGPD4 RANBP2 RGPD3

7.81e-03133573IPR019734
Domain-

CETN3 SPTA1 PLCH1 FKBP14

8.24e-032615741.10.238.10
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 RANBP2 RGPD3

1.55e-0518393MM1549
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

RGPD4 RANBP2 RGPD3 DNAJC2

4.75e-0573394MM14948
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

RGPD4 MFAP1 RANBP2 RGPD3 PPIL4 HTATSF1

1.03e-04277396MM15414
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

RGPD4 RANBP2 RGPD3 DNAJC2

1.17e-0492394MM14951
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RGPD4 RANBP2 RGPD3

1.80e-0440393MM14945
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RGPD4 RANBP2 RGPD3

1.94e-0441393MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RGPD4 RANBP2 RGPD3

2.09e-0442393MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RGPD4 RANBP2 RGPD3

2.24e-0443393MM14609
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RGPD4 RANBP2 RGPD3

2.92e-0447393MM14939
PathwayREACTOME_GENE_SILENCING_BY_RNA

RGPD4 RANBP2 RGPD3

3.30e-0449393MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RGPD4 RANBP2 RGPD3

3.51e-0450393MM14610
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

RGPD4 RANBP2 RGPD3

3.72e-0451393MM15151
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

RGPD4 RANBP2 RGPD3

4.65e-0455393MM14917
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RGPD4 RANBP2 RGPD3

5.44e-0458393MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

RGPD4 RANBP2 RGPD3

5.44e-0458393MM14736
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

RGPD4 RANBP2 RGPD3

7.59e-0465393MM15147
PathwayREACTOME_SUMOYLATION

RGPD4 RANBP2 RGPD3 DNMT1

1.18e-03169394MM14919
PathwayREACTOME_GLUCOSE_METABOLISM

RGPD4 RANBP2 RGPD3

1.49e-0382393MM15394
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

RGPD4 RANBP2 RGPD3

1.60e-0384393MM14929
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

RGPD4 RANBP2 RGPD3

1.71e-0386393MM15413
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

RGPD4 FNBP1 ARHGDIB RANBP2 FAM13A ESYT1 RGPD3

1.80e-03649397MM15690
PathwayREACTOME_MITOTIC_PROMETAPHASE

RGPD4 RANBP2 RGPD3 NCAPH

2.27e-03202394MM15362
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

RGPD4 USP5 RANBP2 CCDC47 RGPD3 SUPT16H ZRANB2 ZCCHC17 PRRC2B DNAJC2 DNMT1

1.64e-08701571130196744
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MFAP1 USP5 RANBP2 RASA3 INF2 CCDC47 ESYT1 SEPTIN9 SUPT16H PPIL4 HLTF CHD7 NCAPH DNMT1

2.73e-081353571429467282
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

FNBP1 MFAP1 RANBP2 WASHC2C FAM13A SEPTIN9 GTSE1 ZRANB2 PLA2G4A CHD7 DNMT1

4.49e-08774571115302935
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

RANBP2 CECR2 SUPT16H ZRANB2 HTATSF1 CHD7 NCAPH HYDIN DNMT1

6.93e-0846957927634302
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

FNBP1 USP5 RANBP2 WASHC2C FAM13A SEPTIN9 GTSE1 PLA2G4A NCAPH

1.25e-0750357916964243
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD4 RANBP2 RGPD3

1.45e-07757330944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD4 RANBP2 RGPD3

1.45e-07757338838144
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RANBP2 RGPD3

1.45e-07757321205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RANBP2 RGPD3

1.45e-07757318949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RANBP2 RGPD3

1.45e-07757325187515
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RANBP2 RGPD3

1.45e-0775739037092
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD4 RANBP2 RGPD3

1.45e-07757323536549
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RANBP2 RGPD3

1.45e-0775738603673
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD4 RANBP2 RGPD3

1.45e-0775737559465
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RANBP2 RGPD3

1.45e-07757326632511
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD4 RANBP2 RGPD3

1.45e-07757317372272
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RANBP2 RGPD3

1.45e-07757324403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RANBP2 RGPD3

1.45e-07757323818861
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD4 RANBP2 RGPD3

1.45e-07757338657106
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RANBP2 RGPD3

1.45e-07757311353387
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD4 RANBP2 RGPD3

1.45e-07757312191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD4 RANBP2 RGPD3

1.45e-07757322821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD4 RANBP2 RGPD3

1.45e-07757320682751
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD4 RANBP2 RGPD3

2.32e-07857322262462
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD4 RANBP2 RGPD3

2.32e-07857321670213
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD4 RANBP2 RGPD3

2.32e-07857328745977
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD4 RANBP2 RGPD3

2.32e-07857327412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD4 RANBP2 RGPD3

2.32e-07857321310149
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

USP5 RANBP2 INF2 CCDC47 ESYT1 SEPTIN9 TOM1 SUPT16H ZRANB2 HTATSF1 NCAPH PRRC2B DNMT1

2.46e-071367571332687490
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD4 RANBP2 RGPD3

3.48e-0795739733766
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD4 RANBP2 RGPD3

3.48e-07957328100513
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RANBP2 RGPD3

3.48e-07957318394993
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD4 RANBP2 RGPD3

3.48e-07957328877029
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD4 RANBP2 RGPD3

3.48e-07957311553612
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD4 RANBP2 RGPD3

3.48e-07957317887960
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD4 RANBP2 RGPD3

3.48e-07957310601307
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD4 RANBP2 RGPD3

4.97e-071057327160050
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD4 RANBP2 RGPD3

4.97e-071057316332688
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD4 RANBP2 RGPD3

4.97e-07105738857542
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD4 RANBP2 RGPD3

4.97e-071057321859863
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

MFAP1 INF2 CCDC47 ESYT1 SUPT16H ZRANB2 HTATSF1 COL14A1 DDHD2 PLCH1 WASHC2A DNAJC2 DNMT1

6.39e-071487571333957083
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

USP5 GPBP1L1 WASHC2C UBE3B ZRANB2 CHD7 ANKS4B WASHC2A NCAPH MGAT4C FHIP1A PRRC2B

6.53e-071242571230973865
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RGPD4 RANBP2 RGPD3

6.82e-071157335771867
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RGPD4 RANBP2 RGPD3

6.82e-071157317069463
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD4 RANBP2 RGPD3

6.82e-071157334110283
Pubmed

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

RANBP2 INF2 CCDC47 ESYT1 PLA2G4A CHD7

7.29e-0719157631177093
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

RANBP2 WASHC2C SEPTIN9 WASHC2A PRRC2B DNAJC2 DNMT1 RPS6KC1

1.05e-0647557831040226
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RGPD4 RANBP2 RGPD3

1.18e-061357331427429
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

VIPAS39 WASHC2C INF2 CCDC47 ESYT1 TOM1 WASHC2A RPS6KC1

1.63e-0650457834432599
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RGPD4 RANBP2 RGPD3

1.87e-061557314697343
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

RGPD4 FNBP1 RANBP2 RGPD3 LRRC7 PRRC2B

2.20e-0623157616452087
Pubmed

Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).

WASHC2C WASHC2A

2.64e-06257220827171
Pubmed

FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans.

WASHC2C WASHC2A

2.64e-06257236717248
Pubmed

Identification of a novel Rev-interacting cellular protein.

WASHC2C WASHC2A

2.64e-06257215847701
Pubmed

Characterization of a family of RanBP2-type zinc fingers that can recognize single-stranded RNA.

RANBP2 ZRANB2

2.64e-06257221256132
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

MFAP1 RANBP2 ESYT1 GTSE1 PLA2G4A NCAPH

3.97e-0625657633397691
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

RGPD4 RANBP2 RGPD3 GTSE1 CHD7

4.27e-0614657523892456
Pubmed

Genomic analysis of mouse retinal development.

VIPAS39 WASHC2C RASA3 CCDC47 SUPT16H CPE PLCH1 WASHC2A NCAPH PRRC2B

4.93e-061006571015226823
Pubmed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

RGPD4 RANBP2 RGPD3

6.29e-062257327717094
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

MFAP1 SUPT16H ZRANB2 PPIL4 CHD7 DNMT1

7.05e-0628357630585729
Pubmed

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.

WASHC2C SEPTIN9 DDHD2 WASHC2A NCAPH FKBP14

8.43e-0629257612819125
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

RANBP2 WASHC2C ESYT1 SEPTIN9 GTSE1 ZCCHC17 WASHC2A FHIP1A PRRC2B

9.65e-0685357928718761
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

MFAP1 CCDC47 ESYT1 SEPTIN9 SUPT16H PPIL4 COL14A1 ZCCHC17 CHD7 PRRC2B DNMT1

1.19e-051371571136244648
Pubmed

Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

RGPD4 RANBP2 SUPT16H PPIL4 NCAPH

1.25e-0518257532239614
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

RGPD4 RANBP2 VIPAS39 WASHC2C GUCY1B1 SEPTIN9 RGPD3 LRRC7 WASHC2A RPS6KC1

1.45e-051139571036417873
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

USP5 RANBP2 CCDC47 SEPTIN9 SUPT16H ZRANB2 HLTF HTATSF1 NCAPH DNAJC2 DNMT1

1.60e-051415571128515276
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

MFAP1 INF2 SEPTIN9 ZRANB2 PPIL4 HTATSF1 WASHC2A

1.87e-0550657730890647
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

RANBP2 CCDC47 SEPTIN9 RGPD3 SUPT16H HTATSF1 NCAPH DNMT1

1.87e-0570457829955894
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

USP5 RANBP2 INF2 CCDC47 ESYT1 GTSE1 TOM1 SUPT16H HLTF NCAPH PRRC2B

1.88e-051440571130833792
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RGPD4 MFAP1 RANBP2 CCDC47 SPTA1 RGPD3 SUPT16H PLCH1 NCAPH PRRC2B RPS6KC1

1.91e-051442571135575683
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

MFAP1 RANBP2 SEPTIN9 GTSE1 SUPT16H PPIL4 HTATSF1 CHD7 DNMT1

2.34e-0595457936373674
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

MFAP1 VIPAS39 GUCY1B1 CCDC47 CHD7 PLCH1 WASHC2A DNMT1

2.49e-0573357834672954
Pubmed

Placentation defects are highly prevalent in embryonic lethal mouse mutants.

WASHC2C WASHC2A FHIP1A PRRC2B

2.54e-0510357429539633
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

RANBP2 GPBP1L1 CCDC47 ESYT1 RGPD3 TOM1 ZRANB2 HLTF CHD7 FHIP1A DNAJC2

2.69e-051497571131527615
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

MFAP1 RANBP2 GTSE1 SUPT16H PPIL4

3.24e-0522257537071664
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

RGPD4 RANBP2 RGPD3

3.38e-053857312791264
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

USP5 CETN3 GTSE1 SUPT16H ZRANB2 PPIL4 HLTF PRRC2B DNMT1

3.51e-05100557919615732
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

MFAP1 USP5 RANBP2 SUPT16H PPIL4 HLTF HTATSF1 NCAPH DNMT1

3.76e-05101457932416067
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

RANBP2 INF2 ESYT1 SEPTIN9 NCAPH DNMT1

4.86e-0539957637536630
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

MFAP1 RANBP2 CCDC47 ESYT1 SUPT16H HLTF ZCCHC17 CHD7 NCAPH DNMT1

5.03e-051318571030463901
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

MFAP1 USP5 VIPAS39 HTATSF1 PLCH1

5.27e-0524657515345747
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FNBP1 WASHC2C SEPTIN9 LRRC7 WASHC2A PRRC2B

5.43e-0540757612693553
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD4 RGPD3

5.51e-05757215710750
Pubmed

Topoisomerase II regulates the maintenance of DNA methylation.

SUPT16H DNMT1

5.51e-05757225451918
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

VIPAS39 WASHC2C DDHD2 WASHC2A PRRC2B

5.80e-0525157529778605
Pubmed

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.

MFAP1 SPTA1 SUPT16H ZRANB2 HLTF

6.73e-0525957530404004
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

RGPD4 RANBP2 INF2 SEPTIN9 RGPD3 SUPT16H CHD7

7.17e-0562657733644029
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

FNBP1 ARHGDIB RANBP2 SEPTIN9 ZRANB2 HLTF CHD7 PRRC2B DNMT1

7.19e-05110357934189442
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

RANBP2 ESYT1 SEPTIN9 LRRC7 PRRC2B

7.23e-0526357534702444
Pubmed

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.

RGPD4 RANBP2 RGPD3 SUPT16H

7.31e-0513557431077711
Pubmed

A FAM21-containing WASH complex regulates retromer-dependent sorting.

WASHC2C WASHC2A

7.34e-05857219922874
Pubmed

Accelerating functional gene discovery in osteoarthritis.

GPBP1L1 WASHC2C WASHC2A

9.22e-055357333473114
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

RGPD4 RANBP2 WASHC2C INF2 CETN3 RGPD3 HTATSF1 WASHC2A PRRC2B

1.02e-04115557920360068
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

RGPD4 RANBP2 RGPD3 SUPT16H ZRANB2 DNAJC2 DNMT1

1.04e-0466557730457570
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RANBP2 WASHC2C ESYT1 SEPTIN9 HTATSF1 NCAPH PRRC2B DNMT1

1.35e-0493457833916271
Pubmed

A bead-based approach for large-scale identification of in vitro kinase substrates.

MFAP1 INF2 ZRANB2 HTATSF1

1.51e-0416357422113938
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

RGPD4 RANBP2 RGPD3 SUPT16H LRRC7 CHD7 PRRC2B DNMT1

1.67e-0496357828671696
Pubmed

The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

WASHC2C WASHC2A

1.72e-041257219922875
Pubmed

Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour.

WASHC2C WASHC2A

1.72e-041257227390154
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

USP5 RGPD3 TOM1 HYDIN

1.78e-0417057423314748
Cytoband2q12.3

RGPD4 RANBP2

2.04e-04175722q12.3
GeneFamilyWASH complex

WASHC2C WASHC2A

5.43e-0563521331
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLA2G4A PLCH1

6.10e-0419352832
GeneFamilyCyclophilin peptidylprolyl isomerases

RANBP2 PPIL4

6.10e-0419352909
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

RANBP2 ZRANB2

7.47e-042135289
GeneFamilyEF-hand domain containing

CETN3 SPTA1 PLCH1 FKBP14

8.17e-04219354863
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 RANBP2 RGPD3

1.41e-03115353769
GeneFamilyPhospholipases

PLA2G4A PLCH1

2.99e-0342352467
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

CHD7 DNAJC2

4.72e-0353352532
GeneFamilySterile alpha motif domain containing

DDHD2 ANKS4B

1.26e-0288352760
CoexpressionGSE22601_DOUBLE_NEGATIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN

MFAP1 GPBP1L1 RASA3 ESYT1 PPIL4 CPE

4.81e-06200576M6246
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_100

SYCP2L CECR2 ZCCHC17 CHD7 PLCH1

6.54e-0698575Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_100
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM13A CECR2 PLA2G4A PLCH1 FHIP1A

3.34e-06179575fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEPTIN9 CECR2 COL14A1 FHIP1A FKBP14

3.62e-06182575a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM13A CECR2 PLA2G4A PLCH1 FHIP1A

3.92e-06185575fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM13A CECR2 PLA2G4A PLCH1 FHIP1A

4.02e-06186575e83718fabb057100835d3357df407f283d23fe16
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM13A CECR2 PLA2G4A PLCH1 FHIP1A

4.24e-061885754bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNBP1 ARHGDIB GTSE1 NCAPH DNMT1

4.82e-06193575b835d28de9daeec5213172c96f62b332cda53bb5
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GTSE1 PDCL2 PLCH1 NCAPH FHIP1A

4.94e-06194575c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNBP1 ARHGDIB GTSE1 NCAPH DNMT1

5.07e-0619557567670d16ddd5d5ab7bc2254df329f5a7b2581556
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNBP1 ARHGDIB GTSE1 NCAPH DNMT1

5.07e-0619557523dc2f8a3a038195a31feee7e3a51094a7a7c23e
ToppCell10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pre_pro_B_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ARHGDIB SEPTIN9 GTSE1 NCAPH DNMT1

5.59e-061995758e7f9312dec1e3a92b6a0ccc7baa2d46e89c11f3
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GUCY1B1 GTSE1 COL14A1 NCAPH DNMT1

5.73e-06200575dd5b753bb1333fa502b9d3a6d65a53a9882b2451
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FNBP1 SYCP2L PLA2G4A MGAT4C

5.38e-051615748aaca49b53a551395f4025ac4e535c7b0ce41a49
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FNBP1 SYCP2L PLA2G4A MGAT4C

5.38e-05161574deb10628d258fb813c293f81fb71be8e383dc82a
ToppCellfacs-Lung-Endomucin_-18m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGDIB VIPAS39 GTSE1 LRRC7

5.51e-05162574e81dec1db8e5a808d96e58410c91961e5d065c94
ToppCellfacs-Lung-Endomucin_-18m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGDIB VIPAS39 GTSE1 LRRC7

5.51e-05162574d19b469f64c9064cfb82dadb6c8135e28949a02a
ToppCellfacs-Lung-Endomucin_-18m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGDIB VIPAS39 GTSE1 LRRC7

5.51e-0516257410c2aa047f33f48e4abe676236bbdb593079dd1d
ToppCelldroplet-Fat-Gat-18m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKS4B PLCH1 ODAD3 HYDIN

7.11e-05173574f3f67531f72d6d52e19c7f1f2db1ab4026fb70da
ToppCelldroplet-Fat-Gat-18m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKS4B PLCH1 ODAD3 HYDIN

7.11e-05173574a40a52d8041d45dc3bef74fe55945ae07aa018d6
ToppCelldroplet-Fat-Gat-18m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKS4B PLCH1 ODAD3 HYDIN

7.11e-05173574f0b4dd1cf41d6ee6abb0e1968b8b39f4fabebcb5
ToppCelldroplet-Kidney-nan-3m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNBP1 ARHGDIB SEPTIN9 NCAPH

7.27e-051745740e541581df2d4249270b28ceded6298329013580
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLA2G4A COL14A1 LRRC7 MGAT4C

7.44e-05175574795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP2 SUPT16H COL14A1 CPE

7.60e-05176574749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ARHGDIB PLA2G4A COL14A1 CPE

8.29e-051805742ccc77d769d3ffd77ab3af45e4f192785b6db79c
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGDIB RASA3 HLTF CCDC116

8.47e-05181574d90faa6115b408c9fbca61fc90ff951e070754ba
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM13A PLA2G4A PLCH1 FHIP1A

8.66e-0518257417ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SEPTIN9 CECR2 PLA2G4A COL14A1

9.03e-051845748fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM13A CECR2 PLA2G4A FHIP1A

9.03e-05184574ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CECR2 PLA2G4A PLCH1 FHIP1A

9.22e-05185574929b68b05b7686341329ac756d7df172cb4b810b
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NUTM1 GTSE1 PDCL2 NCAPH

9.41e-0518657486d145f965c311189e7996390eef491642417c5c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEPTIN9 CECR2 COL14A1 FHIP1A

9.61e-0518757477886f99c229610abd28c4c370d2c7d1536c9782
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

ARHGDIB RASA3 GUCY1B1 COL14A1

1.00e-04189574f4865b7db16de15120504147a8016ac522ad242a
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL14A1 KCNS3 LRRC7 CPE

1.02e-04190574c01a8bfb9fbc0e6f37d7e9be25512eda63acabbc
ToppCellP15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ARHGDIB PLA2G4A COL14A1 CPE

1.02e-04190574d072bb285bd34d518b958e7c9ad44739c60b359c
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGDIB GTSE1 NCAPH DNMT1

1.02e-04190574b65383e256b04122500b742caeed0b807793851e
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGDIB GTSE1 NCAPH DNMT1

1.02e-0419057489095d3e023269d89c82e3a73550f869e3f34201
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLA2G4A COL14A1 CPE MGAT4C

1.13e-041955743c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell10x5'v1-week_17-19|World / cell types per 3 fetal stages;per 3',per 5'

ARHGDIB SEPTIN9 GTSE1 NCAPH

1.15e-0419657431229affb48521e8be93b6061178fd8cea09ba99
ToppCellMS-CD4-exh_CD4|MS / Condition, Cell_class and T cell subcluster

FNBP1 ARHGDIB SEPTIN9 DNMT1

1.15e-04196574d0217eccaa2cbf4ce9934e9d2e0c34a7f5c1a57e
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

FAM13A ZRANB2 PLA2G4A FHIP1A

1.17e-041975741a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes-Pericyte|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GUCY1B1 COL14A1 KCNS3 CPE

1.17e-04197574452be45f4aac8459dd860493171f5f715368d663
ToppCellerythropoietic-Polychromatic_Erythroblast|World / Lineage and Cell class

FAM13A SPTA1 HLTF NCAPH

1.17e-04197574604fcbf47f073c2af344e1b16b615a78ef838dc9
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGDIB GTSE1 NCAPH DNMT1

1.20e-04198574d484ac79d6cd29f1d9c192d126c2099f737d5320
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FAM13A CECR2 PLA2G4A FHIP1A

1.20e-04198574285f729140b1df029c24f6ca1d2438470ac51794
ToppCellmetastatic_Brain-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

ARHGDIB GUCY1B1 KCNS3 CPE

1.20e-0419857486a4c8e859ce11a95875f8844963baeb1ba898ec
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGDIB GTSE1 NCAPH DNMT1

1.20e-04198574ac0be1666456cfa8d68588b187d65008e6d5c0e2
ToppCellSigmoid-Dendritic_cell-cycling_DCs|Sigmoid / Region, Cell class and subclass

GTSE1 KCNS3 NCAPH CCDC116

1.22e-04199574bd6f8c0f79e9a94cc0f8c6105d38851463de821c
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGDIB GTSE1 NCAPH DNMT1

1.22e-041995740cae9c80c15542fd86a82d7b6d6a3ad690cee410
ToppCellSigmoid-(5)_Dendritic_cell-(52)_cycling_DCs|Sigmoid / shred on region, Cell_type, and subtype

GTSE1 KCNS3 NCAPH CCDC116

1.22e-041995748ee78a39729633bcbb3ab17e1dfaca33f38db569
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pre_pro_B_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ARHGDIB GTSE1 NCAPH DNMT1

1.22e-0419957499778178e3ec121802db938db8c5475d19b43fec
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GTSE1 CHD7 NCAPH DNMT1

1.22e-0419957453b3d35767889a152f1f38e8f6f0ba8f7a7690f2
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FAM13A CECR2 ZRANB2 PLA2G4A

1.24e-04200574e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_vent / Disease condition, Lineage, Cell class and subclass

GTSE1 SUPT16H NCAPH DNMT1

1.24e-042005747e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

GTSE1 SUPT16H NCAPH DNMT1

1.24e-042005749775ca7dedb76fcbb74f80f86b33c94e394c320a
Diseasecholesteryl ester 24:5 measurement

AXDND1 SYCP2L

2.07e-0412532EFO_0021448
DiseasePolynesian Bronchiectasis

ODAD3 HYDIN

1.81e-0335532C4317124
DiseaseCiliary Dyskinesia, Primary, 1, With Or Without Situs Inversus

ODAD3 HYDIN

1.81e-0335532C4551906
DiseaseKartagener Syndrome

ODAD3 HYDIN

1.81e-0335532C0022521
DiseasePrimary ciliary dyskinesia

ODAD3 HYDIN

1.92e-0336532cv:C0008780
DiseasePrimary Ciliary Dyskinesia

ODAD3 HYDIN

3.25e-0347532C4551720

Protein segments in the cluster

PeptideGeneStartEntry
LEVEVFDKDLDKDDF

ESYT1

716

Q9BSJ8
RDKAEIEDEDEDEFK

CCDC116

586

Q8IYX3
FFAEQIEKDDREDKE

DNMT1

631

P26358
EDLEFKISDEEADDA

CHD7

761

Q9P2D1
EFSYLDEEEKEKAEC

DNAJC2

226

Q99543
EEKKTKDLFELDDDF

CECR2

426

Q9BXF3
FEKDDDAYKTEDSDD

RANBP2

1996

P49792
KSHFDFEEEDVDKLE

RASA3

211

Q14644
IEFEKEEDCEKAFFK

PPIL4

286

Q8WUA2
DALVEDIFDKEDEDK

FKBP14

181

Q9NWM8
DIFDKEDEDKDGFIS

FKBP14

186

Q9NWM8
TENKLKDDDFEEESF

MGAT4C

321

Q9UBM8
ESSDEEDEEFQFIKK

MFAP1

51

P55081
LKKEEEDDYEAASDF

RPS6KC1

251

Q96S38
FEFEDKKEDDENAGK

LRRC7

461

Q96NW7
EDKVEKLQFEEEDFP

GPBP1L1

146

Q9HC44
KFDDFEDEEDIVEYD

CCDC47

21

Q96A33
LAQLKEAEDEFDEED

PDCL2

51

Q8N4E4
EFFDIFEKEKVDKEA

DDHD2

401

O94830
FEESSLFEKELEKFD

KCNS3

146

Q9BQ31
IEEKESKEEDFYEDL

GUCY1B1

181

Q02153
SKEEDFYEDLDRFEE

GUCY1B1

186

Q02153
EEEEDSFSGDFKEKL

ANKS4B

236

Q8N8V4
SFFKEIKEEEEGSED

FAM13A

876

O94988
KEDILLLADEKFDFD

GTSE1

6

Q9NYZ3
EAFEEAKAEDEEELL

INF2

246

Q27J81
KKKEAEEEDEELSNF

NUTM1

1006

Q86Y26
EKEEEEDTYEKVFDD

HTATSF1

626

O43719
KVFDDESDEKEDEEY

HTATSF1

636

O43719
KKAEEGDADEKLFEE

HTATSF1

661

O43719
GDADEKLFEESDDKE

HTATSF1

666

O43719
KLFEESDDKEDEDAD

HTATSF1

671

O43719
GKEVEDADEKLFEDD

HTATSF1

686

O43719
DADEKLFEDDDSNEK

HTATSF1

691

O43719
LFEDDDSNEKLFDEE

HTATSF1

696

O43719
LFDEEEDSSEKLFDD

HTATSF1

706

O43719
FEKDDDAYKTEDSDD

RGPD3

1021

A6NKT7
KKELEDEEDDFDSFI

FHIP1A

801

Q05DH4
DDLIKEEKDETDEFF

HYDIN

351

Q4G0P3
EEDDDDELDSKLNYK

ARHGDIB

11

P52566
EMKVLATDFDDEFDD

FNBP1

531

Q96RU3
KKDESEEDEEEPDFA

FAM163B

36

P0C2L3
FVDDFDAFKKIEDEL

COL14A1

1191

Q05707
KEFIEPEIDESFKED

AXDND1

836

Q5T1B0
DFELESFSERKEEEK

CPE

446

P16870
KDAFELFDTDKDEAI

CETN3

31

O15182
EEILKAFKLFDDDDS

CETN3

101

O15182
AIDFDLLEDEESKKF

FAM118B

76

Q9BPY3
KTEFDKLFEDLKEDD

HLTF

211

Q14527
EEKEIADFDIFDDPE

PLA2G4A

661

P47712
FEKDDDAYKTEDSDD

RGPD4

1021

Q7Z3J3
KFFDEESEEEDNEVV

ODAD3

556

A5D8V7
KEFDEDSEDRLVNEK

SEPTIN9

476

Q9UHD8
TDFDFPEEDKKEEFE

RNASE9

31

P60153
FLKNEDEEEEEEEKD

SUPT16H

431

Q9Y5B9
TKKDFEIDFEDDIDF

NCAPH

466

Q15003
EEEEKEEAKSAEFEK

ZCCHC17

161

Q9NP64
EEFDKFLEERAKAAD

TOM1

441

O60784
EAFKEIKDREFETDS

SYCP2L

261

Q5T4T6
YSEKLKFSDDEEEEE

PRRC2B

381

Q5JSZ5
KTSLFEEDKEDDLFA

WASHC2C

661

Q9Y4E1
EEDKEDDLFAIAKDS

WASHC2C

666

Q9Y4E1
KFKAFTFDDEDDELS

VIPAS39

16

Q9H9C1
EEDEHEPKFEKFLDA

SPTA1

2311

P02549
DEDSADEIEDECKFK

PLCH1

461

Q4KWH8
EEEDEDEDLSKYKLD

ZRANB2

156

O95218
DEDLSKYKLDEDEDE

ZRANB2

161

O95218
KYKLDEDEDEDDADL

ZRANB2

166

O95218
EIDDFFKADDPESTK

UBE3B

56

Q7Z3V4
KTSLFEEDEEDDLFA

WASHC2A

661

Q641Q2
EEDEEDDLFAIAKDS

WASHC2A

666

Q641Q2
GFDLSEEKFELDEDV

USP5

106

P45974