Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	procollagen glucosyltransferase activity	PLOD3 PLOD1	6.56e-05	3	94	2	GO:0033823
GeneOntologyMolecularFunction	procollagen-lysine 5-dioxygenase activity	PLOD3 PLOD1	6.56e-05	3	94	2	GO:0008475
GeneOntologyMolecularFunction	peptidyl-lysine 5-dioxygenase activity	PLOD3 PLOD1	1.31e-04	4	94	2	GO:0070815
GeneOntologyMolecularFunction	iron ion binding	PLOD3 CYP4Z1 ABCE1 CYP4F22 PLOD1 NFU1	1.34e-04	166	94	6	GO:0005506
GeneOntologyMolecularFunction	MHC class II protein complex binding	HLA-DMA HLA-DQA1 HSP90AA1	2.72e-04	27	94	3	GO:0023026
Domain	LYS_HYDROXYLASE	PLOD3 PLOD1	7.65e-05	3	95	2	PS01325
Domain	K_chnl_volt-dep_ERG	KCNH6 KCNH2	7.65e-05	3	95	2	IPR003967
Domain	Procol_lys_dOase	PLOD3 PLOD1	7.65e-05	3	95	2	IPR001006
Domain	MHC_II_alpha	HLA-DMA HLA-DQA1	3.79e-04	6	95	2	PF00993
Domain	MHC_II_a_N	HLA-DMA HLA-DQA1	5.29e-04	7	95	2	IPR001003
Domain	PAS_9	KCNH6 KCNH2	1.12e-03	10	95	2	PF13426
Domain	MKP	DUSP8 DUSP9	1.12e-03	10	95	2	IPR008343
Domain	-	KCNH6 KCNH2 GGCX	1.87e-03	48	95	3	2.60.120.10
Domain	RmlC-like_jellyroll	KCNH6 KCNH2 GGCX	2.22e-03	51	95	3	IPR014710
Domain	K_chnl_volt-dep_EAG/ELK/ERG	KCNH6 KCNH2	2.24e-03	14	95	2	IPR003938
Domain	P4Hc	PLOD3 PLOD1	2.93e-03	16	95	2	SM00702
Domain	Pro_4_hyd_alph	PLOD3 PLOD1	2.93e-03	16	95	2	IPR006620
Domain	AT_hook	KMT2C DOT1L	2.93e-03	16	95	2	PF02178
Domain	2OG-FeII_Oxy	PLOD3 PLOD1	4.14e-03	19	95	2	PF03171
Domain	-	SACS HSP90AA1	4.58e-03	20	95	2	3.30.565.10
Domain	FE2OG_OXY	PLOD3 PLOD1	5.05e-03	21	95	2	PS51471
Domain	HATPase_C	SACS HSP90AA1	5.05e-03	21	95	2	IPR003594
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	NPTX1 INTS5 OGT SACS RBBP6 RBFOX1 KCTD3 ELAVL2 USP39 PZP SRRM2 CWC22 PLOD1 SDAD1 SEC23B HSP90AA1	3.80e-08	1082	95	16	38697112
Pubmed	MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.	XPO5 RBBP6 ABCE1 DUSP9 KCTD3 USP39	3.69e-06	150	95	6	22678362
Pubmed	Cloning and characterization of a third human lysyl hydroxylase isoform.	PLOD3 PLOD1	7.38e-06	2	95	2	9724729
Pubmed	Characterization of a cancer-associated Epstein-Barr virus EBNA1 variant reveals a novel interaction with PLOD1 and PLOD3.	PLOD3 PLOD1	7.38e-06	2	95	2	34304093
Pubmed	MYO6 knockdown inhibits the growth and induces the apoptosis of prostate cancer cells by decreasing the phosphorylation of ERK1/2 and PRAS40.	MYO6 AKT1S1	7.38e-06	2	95	2	27431378
Pubmed	The hERG channel is dependent upon the Hsp90α isoform for maturation and trafficking.	KCNH2 HSP90AA1	7.38e-06	2	95	2	22554505
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	KMT2C PLOD3 MYO6 DUSP9 MICAL3 USP39 QARS1 PLOD1 SDAD1	9.16e-06	497	95	9	36774506
Pubmed	Developmentally regulated expression of the mouse homologues of the potassium channel encoding genes m-erg1, m-erg2 and m-erg3.	KCNH6 KCNH2	2.21e-05	3	95	2	14643686
Pubmed	Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG.	KCNH2 HSP90AA1	2.21e-05	3	95	2	12775586
Pubmed	Characterization of cDNAs for mouse lysyl hydroxylase 1, 2 and 3, their phylogenetic analysis and tissue-specific expression in the mouse.	PLOD3 PLOD1	2.21e-05	3	95	2	10429951
Pubmed	Identification of amino acids important for the catalytic activity of the collagen glucosyltransferase associated with the multifunctional lysyl hydroxylase 3 (LH3).	PLOD3 PLOD1	2.21e-05	3	95	2	11896059
Pubmed	Characterization of three fragments that constitute the monomers of the human lysyl hydroxylase isoenzymes 1-3. The 30-kDa N-terminal fragment is not required for lysyl hydroxylase activity.	PLOD3 PLOD1	2.21e-05	3	95	2	11956192
Pubmed	Lysyl hydroxylase 3 is a multifunctional protein possessing collagen glucosyltransferase activity.	PLOD3 PLOD1	2.21e-05	3	95	2	10934207
Pubmed	Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins.	KCNH2 HSP90AA1	2.21e-05	3	95	2	23963841
Pubmed	Procollagen-lysine, 2-oxoglutarate 5-dioxygenases 1, 2, and 3 are potential prognostic indicators in patients with clear cell renal cell carcinoma.	PLOD3 PLOD1	2.21e-05	3	95	2	31446433
Pubmed	Primary structure, tissue distribution, and chromosomal localization of a novel isoform of lysyl hydroxylase (lysyl hydroxylase 3).	PLOD3 PLOD1	2.21e-05	3	95	2	9582318
Pubmed	Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome.	KCNH6 KCNH2	2.21e-05	3	95	2	35818223
Pubmed	The lysyl hydroxylase isoforms are widely expressed during mouse embryogenesis, but obtain tissue- and cell-specific patterns in the adult.	PLOD3 PLOD1	2.21e-05	3	95	2	16996725
Pubmed	HERG K(+) currents in human prolactin-secreting adenoma cells.	KCNH6 KCNH2	2.21e-05	3	95	2	12634931
Pubmed	The genes encoding mouse lysyl hydroxylase isoforms map to chromosomes 4,5, and 9.	PLOD3 PLOD1	2.21e-05	3	95	2	11130984
Pubmed	Kv4.3 Modulates the Distribution of hERG.	KCNH2 HSP90AA1	4.41e-05	4	95	2	29259226
Pubmed	Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes.	PLOD3 PLOD1	4.41e-05	4	95	2	16467571
Pubmed	Antigen presentation and T cell development in H2-M-deficient mice.	HLA-DMA HLA-DQA1	4.41e-05	4	95	2	8638109
Pubmed	Genome-wide association study of vitamin D concentrations in Hispanic Americans: the IRAS family study.	KMT2C RBFOX1	4.41e-05	4	95	2	20600896
Pubmed	H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection.	HLA-DMA HLA-DQA1	4.41e-05	4	95	2	8598041
Pubmed	PLODs are overexpressed in ovarian cancer and are associated with gap junctions via connexin 43.	PLOD3 PLOD1	4.41e-05	4	95	2	33483598
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	CACNA1A KCNH6 KMT2C PCDH11Y BSN SRRM2	4.48e-05	233	95	6	37704626
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	DPP7 PLOD3 PXDN MYO6 ABCE1 TMEM231 PLOD1 GGCX HSP90AA1	4.73e-05	613	95	9	22268729
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TCAF2 TRAPPC11 LRR1 MYO6 ABCE1 ELAVL2 USP39 BSN FAM149A	6.43e-05	638	95	9	31182584
Pubmed	Reconstitution of an operational MHC class II compartment in nonantigen-presenting cells.	HLA-DMA HLA-DQA1	7.34e-05	5	95	2	7985028
Pubmed	MHC class II expression in double mutant mice lacking invariant chain and DM functions.	HLA-DMA HLA-DQA1	7.34e-05	5	95	2	9551894
Pubmed	H2-Mbeta 1 and H2-Mbeta 2 heterodimers equally promote clip removal in I-A(q) molecules from autoimmune-prone DBA/1 mice.	HLA-DMA HLA-DQA1	7.34e-05	5	95	2	11148202
Pubmed	Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway.	HLA-DMA HLA-DQA1	7.34e-05	5	95	2	8598040
Pubmed	Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90.	OGT HSP90AA1	7.34e-05	5	95	2	30699359
Pubmed	Invariant chain-independent function of H-2M in the formation of endogenous peptide-major histocompatibility complex class II complexes in vivo.	HLA-DMA HLA-DQA1	7.34e-05	5	95	2	9432982
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	DPP7 SMAP1 KCTD3 SNX27 MICAL3 CWC22 SEC23B	8.24e-05	378	95	7	34315543
Pubmed	Human transcription factor protein interaction networks.	KMT2C OGT MYO6 RBBP6 ETV4 GON4L ELAVL2 MECOM DOT1L QARS1 SRRM2 SDAD1 SEC23B	1.37e-04	1429	95	13	35140242
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	PLOD3 PXDN XPO5 TMEM259 COQ8B MICAL3 USP39 QARS1 SLC25A28 PLOD1 SDAD1 HSP90AA1 LRCH3	1.48e-04	1440	95	13	30833792
Pubmed	Premature aggregation of type IV collagen and early lethality in lysyl hydroxylase 3 null mice.	PLOD3 PLOD1	1.54e-04	7	95	2	15377789
Pubmed	Altered antigen presentation in mice lacking H2-O.	HLA-DMA HLA-DQA1	1.54e-04	7	95	2	9492004
Pubmed	The impact of H2-DM on humoral immune responses.	HLA-DMA HLA-DQA1	1.54e-04	7	95	2	11714799
Pubmed	Heat shock protein 90 mediates protein-protein interactions between human aminoacyl-tRNA synthetases.	QARS1 HSP90AA1	2.05e-04	8	95	2	10913161
Pubmed	A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease.	AGL HSP90AA1	2.05e-04	8	95	2	17908927
Pubmed	Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept.	RBFOX1 BSN	2.05e-04	8	95	2	19567891
Pubmed	Co-chaperone FKBP38 promotes HERG trafficking.	KCNH2 HSP90AA1	2.05e-04	8	95	2	17569659
Pubmed	Cloning and expression analysis of murine phospholipase D1.	MECOM CRH	2.05e-04	8	95	2	9307024
Pubmed	Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis.	QARS1 HSP90AA1	2.62e-04	9	95	2	10791971
Pubmed	C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.	OGT XPO5 USP39 SRRM2	3.26e-04	119	95	4	35776542
Pubmed	Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate.	KCNH6 KCNH2	3.28e-04	10	95	2	26503718
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	PLOD3 OGT XPO5 ABCE1 AGL DUSP9 KCTD3 SNX27 SRRM2 PLOD1	3.34e-04	974	95	10	28675297
Pubmed	Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.	KMT2C OGT SACS	3.53e-04	50	95	3	37974198
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	CACNA1A SACS NRG2 MICAL3 BSN SRRM2	3.90e-04	347	95	6	17114649
Pubmed	A protein interaction framework for human mRNA degradation.	DPP7 KCTD3 SRRM2 CWC22 SLC27A5 HSP90AA1	3.90e-04	347	95	6	15231747
Pubmed	A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.	OGT XPO5 ABCE1 HSP90AA1	3.93e-04	125	95	4	21654808
Pubmed	Fgf20 is required for sensory epithelial specification in the developing cochlea.	MYO6 ETV4	4.00e-04	11	95	2	18524904
Pubmed	Dynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activation.	HLA-DMA HLA-DQA1	4.00e-04	11	95	2	11854359
Pubmed	MHC class II antigen presentation pathway in murine tumours: tumour evasion from immunosurveillance?	HLA-DMA HLA-DQA1	4.00e-04	11	95	2	11027433
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DENND4A OGT ABCE1 GON4L MICAL3 PZP CWC22 SEC23B	4.16e-04	650	95	8	38777146
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	OGT XPO5 TMEM259 PCNX1 QARS1 PLOD1 GGCX HSP90AA1	4.47e-04	657	95	8	36180527
Pubmed	Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair.	DOT1L BSN	4.79e-04	12	95	2	28700933
Pubmed	Multiple roles of integrin-α3 at the neuromuscular junction.	CACNA1A BSN	4.79e-04	12	95	2	28386022
Pubmed	HIV-1 Nef impairs MHC class II antigen presentation and surface expression.	HLA-DMA HLA-DQA1	4.79e-04	12	95	2	11593029
Pubmed	Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.	HLA-DMA HLA-DQA1	4.79e-04	12	95	2	12970439
Pubmed	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	KIF6 RBFOX1	5.65e-04	13	95	2	18846501
Pubmed	Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans.	DHH MYO6	5.65e-04	13	95	2	18632939
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PLOD3 DUSP8 DUSP9 KCTD3 SNX27 MICAL3 SRRM2 PLOD1 SDAD1 HSP90AA1	5.95e-04	1049	95	10	27880917
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	DPP7 PRPSAP2 METTL1 OGT XPO5 ABCE1 AGL QARS1 PLOD1 AKT1S1 SEC23B HSP90AA1	6.08e-04	1455	95	12	22863883
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	OGT MYO6 ABCE1 AGL RBFOX1 DUSP9 QARS1 PLOD1 SEC23B GGCX HSP90AA1	6.40e-04	1257	95	11	37317656
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	KMT2C OGT RBBP6 USP39 CWC22	6.43e-04	251	95	5	31076518
Pubmed	HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4.	HLA-DMA HLA-DQA1	6.58e-04	14	95	2	7512597
Pubmed	Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.	CACNA1A BSN	6.58e-04	14	95	2	21228161
Pubmed	Interaction of CD4 with HLA class II antigens and HIV gp120.	HLA-DMA HLA-DQA1	6.58e-04	14	95	2	1869305
Pubmed	Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners.	MYO6 AGL QARS1	6.64e-04	62	95	3	26508657
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	PRPSAP2 TRAPPC11 MYO6 UTP15 ABCE1 AGL SNX27 SEC23B	7.01e-04	704	95	8	29955894
Pubmed	HIV-1 envelope protein is expressed on the surface of infected cells before its processing and presentation to class II-restricted T lymphocytes.	HLA-DMA HLA-DQA1	7.57e-04	15	95	2	8376762
Pubmed	Envelope glycoproteins of HIV-1 interfere with T-cell-dependent B cell differentiation: role of CD4-MHC class II interaction in the effector phase of T cell help.	HLA-DMA HLA-DQA1	7.57e-04	15	95	2	8168144
Pubmed	Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein.	HLA-DMA HLA-DQA1	7.57e-04	15	95	2	22860026
Pubmed	Endocytosis of endogenously synthesized HIV-1 envelope protein. Mechanism and role in processing for association with class II MHC.	HLA-DMA HLA-DQA1	7.57e-04	15	95	2	7602119
Pubmed	HIV-gp120 can block CD4-class II MHC-mediated adhesion.	HLA-DMA HLA-DQA1	7.57e-04	15	95	2	1967269
Pubmed	The enhanced immune response to the HIV gp160/LAMP chimeric gene product targeted to the lysosome membrane protein trafficking pathway.	HLA-DMA HLA-DQA1	7.57e-04	15	95	2	9079699
Pubmed	AIDS and related syndromes as a viral-induced autoimmune disease of the immune system: an anti-MHC II disorder. Therapeutic implications.	HLA-DMA HLA-DQA1	7.57e-04	15	95	2	3489470
Pubmed	Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner.	MYO6 ETV4	7.57e-04	15	95	2	31276493
Pubmed	Efficient incorporation of HLA class II onto human immunodeficiency virus type 1 requires envelope glycoprotein packaging.	HLA-DMA HLA-DQA1	7.57e-04	15	95	2	10729169
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	KMT2C INTS5 PLOD3 OGT PXDN UTP15 RBBP6 KCTD3 GON4L SDAD1 GGCX LRCH3	7.79e-04	1497	95	12	31527615
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	PRPSAP2 PLOD3 PXDN XPO5 TMEM259 RBBP6 QARS1 SRRM2 PLOD1 SEC23B HSP90AA1	8.28e-04	1297	95	11	33545068
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	MYO6 UTP15 RBBP6 ELAVL2 USP39 QARS1 CWC22 HSP90AA1	8.33e-04	723	95	8	34133714
Pubmed	Inhibition of CD4+ T cell function by the HIV envelope protein, gp120.	HLA-DMA HLA-DQA1	8.64e-04	16	95	2	2846691
Pubmed	Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules.	HLA-DMA HLA-DQA1	8.64e-04	16	95	2	1978941
Pubmed	Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding.	HLA-DMA HLA-DQA1	8.64e-04	16	95	2	2543930
Pubmed	Human immunodeficiency virus type 1 Vpu protein interacts with CD74 and modulates major histocompatibility complex class II presentation.	HLA-DMA HLA-DQA1	8.64e-04	16	95	2	17959659
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PXDN XPO5 SNX27 GON4L MICAL3 SRRM2	8.96e-04	407	95	6	12693553
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	OGT XPO5 UTP15 RBBP6 ABCE1 QARS1 SRRM2 CWC22 PLOD1 SEC23B HSP90AA1	9.43e-04	1318	95	11	30463901
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	PRPSAP2 PLOD3 RBBP6 SNX27 MECOM SRRM2 SDAD1 SEC23B HSP90AA1	9.56e-04	922	95	9	27609421
Pubmed	Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors.	HLA-DMA HLA-DQA1	9.78e-04	17	95	2	15194762
Pubmed	The activity of Nef on HIV-1 infectivity.	HLA-DMA HLA-DQA1	9.78e-04	17	95	2	24904546
Pubmed	Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis.	OGT HSP90AA1	9.78e-04	17	95	2	29208956
Pubmed	A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.	RBBP6 ABCE1 RBFOX1 ZBTB12 SDAD1 SEC23B	1.04e-03	419	95	6	28700943
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	NPTX1 PLOD3 MYO6 COQ8B PLOD1 GGCX YIPF6 LRCH3	1.09e-03	754	95	8	33060197
Pubmed	HIV-1 Nef promotes endocytosis of cell surface MHC class II molecules via a constitutive pathway.	HLA-DMA HLA-DQA1	1.10e-03	18	95	2	19620308
Pubmed	Reciprocal modulation of transcriptional activities between HIV-1 Tat and MHC class II transactivator CIITA.	HLA-DMA HLA-DQA1	1.10e-03	18	95	2	11118314
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2C MECOM DOT1L	2.56e-04	34	66	3	487
GeneFamily	MAP kinase phosphatases	DUSP8 DUSP9	7.07e-04	11	66	2	895
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1A KCNH6 NPTX1 KCNH2 BSN CDH18 FAM149A	1.61e-07	188	95	7	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1A RBFOX1 VRTN ABCB11 CYP4F22 CDH18	8.45e-07	150	95	6	0205318a870e091add66ee4305747dda9f51510d
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1A KCNH6 KCNH2 BSN CDH18 FAM149A	2.95e-06	186	95	6	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1A KCNH6 NPTX1 KCNH2 RBFOX1 CDH18	3.33e-06	190	95	6	40d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1A KCNH6 NPTX1 KCNH2 RBFOX1 CDH18	3.33e-06	190	95	6	f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1A KCNH6 NPTX1 KCNH2 RBFOX1 CDH18	3.33e-06	190	95	6	a9a705455019e28d655636de73b07540798f82e6
ToppCell	15-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	CACNA1A KCNH6 NPTX1 KCNH2 RBFOX1 CDH18	3.44e-06	191	95	6	76311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCell	COVID-19_Severe-CD8+_Tem\|COVID-19_Severe / Disease condition and Cell class	FCRL3 MYO6 HLA-DQA1 CHST12 PZP F2R	3.87e-06	195	95	6	ff7ae62393e1c858a10592db8e6d9f36b8bae396
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FCRL3 MYO6 DUSP8 CHST12 PZP F2R	4.23e-06	198	95	6	a1b310274aa9b3d2aa1fe9488d67422bf4ac81d2
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FCRL3 MYO6 DUSP8 CHST12 PZP F2R	4.23e-06	198	95	6	76aff381403bc5a8a9cc73eb1e5dbdc0bac7de6c
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	FCRL3 MYO6 DUSP8 CHST12 PZP F2R	4.23e-06	198	95	6	a781fd35a7cda8b7760c2e3ddccaac7aac26c979
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FCRL3 MYO6 DUSP8 CHST12 PZP F2R	4.23e-06	198	95	6	df399674345c45738d765a8354ea8d1484572c34
ToppCell	COVID-19_Mild-Lymphoid_T/NK-gd_T\|COVID-19_Mild / Disease group, lineage and cell class	FCRL3 MYO6 DUSP8 CHST12 PZP F2R	4.23e-06	198	95	6	6aea5d00c417708f05b6d2dfe5a962d80864f8eb
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-gd_T\|COVID-19_Mild / Disease, condition lineage and cell class	FCRL3 MYO6 DUSP8 CHST12 PZP F2R	4.48e-06	200	95	6	6560753d3df2f87860b52052d4881aa45410f666
ToppCell	mild-gd_T\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FCRL3 MYO6 DUSP8 CHST12 PZP F2R	4.48e-06	200	95	6	2c21ede46a42b8e2f8e99ecca365baa52056eb17
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FCRL3 MYO6 DUSP8 PZP SRRM2 F2R	4.48e-06	200	95	6	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	VE-CD8-antiviral_CD4\|VE / Condition, Cell_class and T cell subcluster	FCRL3 CHST12 TMEM231 PZP F2R	1.64e-05	148	95	5	f49f579650b57cc4c6c7a7fa726447740d3dc695
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1A RBFOX1 VRTN CYP4F22 CDH18	2.61e-05	163	95	5	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	Ciliated_cells-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	DNAJB13 KIF6 BCO2 TMEM231 ZBBX	2.85e-05	166	95	5	4b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KMT2C HMX3 HTR3E VRTN NRG2	3.02e-05	168	95	5	8072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell	COVID-19_Moderate-B_intermediate\|COVID-19_Moderate / disease group, cell group and cell class	CACNA1A FCRL3 HLA-DMA HLA-DQA1 MICAL3	3.87e-05	177	95	5	68e3d12a0c048a2d0f1b9680c7338a35855bba30
ToppCell	COVID-19_Moderate-B_intermediate\|World / disease group, cell group and cell class	CACNA1A FCRL3 HLA-DMA HLA-DQA1 MICAL3	4.20e-05	180	95	5	bd81b87a6dc81e5ab4a6c948eb0c80f14401a6a7
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	CACNA1A KCNH6 KCNH2 BSN CDH18	4.42e-05	182	95	5	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 RBFOX1 ETV4 MECOM PLCD1	4.42e-05	182	95	5	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	droplet-Marrow-nan-3m-Myeloid-Cd4_positive_Macrophages\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	METTL1 ABCE1 TMEM97 ZBTB12 SDAD1	4.54e-05	183	95	5	92ef926e6c1de8477fa4f35d1dae85482d8009de
ToppCell	droplet-Marrow-nan-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	METTL1 ABCE1 TMEM97 ZBTB12 SDAD1	4.54e-05	183	95	5	24db9cc717e651586317c6a8e03a3401651273c1
ToppCell	18-Distal-Epithelial-Neuroendocrine\|Distal / Age, Tissue, Lineage and Cell class	CACNA1A KCNH6 NPTX1 RBFOX1 CRH	4.78e-05	185	95	5	f8fc7b12b4e18d23d84e95488be93c4352d325f3
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A NPTX1 RBFOX1 BSN CDH18	4.91e-05	186	95	5	d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCell	21-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	CACNA1A KCNH6 NPTX1 RBFOX1 CDH18	5.16e-05	188	95	5	e78d4f7a5d28c77503cb041ff585d13df4c88bd2
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A NPTX1 RBFOX1 BSN CDH18	5.29e-05	189	95	5	f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCell	(1)_T_cells-(1)_T_CD8_gd\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	FCRL3 MYO6 HLA-DQA1 F2R HSP90AA1	5.43e-05	190	95	5	268772d2adff34f7175b8474e95b67fd96dc1234
ToppCell	facs-Marrow-KLS-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLOD3 NRG2 TMEM97 SDAD1 FAM149A	5.43e-05	190	95	5	c03c735a0ed850bf460a1847f5e2dd61753e577d
ToppCell	mild_COVID-19-gd_T\|mild_COVID-19 / disease group, cell group and cell class (v2)	PXDN MYO6 DUSP8 CHST12 F2R	5.56e-05	191	95	5	0e43c097b92aaa831811d60e033262999e79dcd7
ToppCell	metastatic_Brain-T/NK_cells-Exhausted_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	HLA-DMA HLA-DQA1 CHST12 F2R HSP90AA1	5.56e-05	191	95	5	2ffd40ebf1d63e61a97208ddcbeb6a86e409f9d8
ToppCell	COVID-19_Severe-B_intermediate\|World / disease group, cell group and cell class	CACNA1A FCRL3 HLA-DMA HLA-DQA1 MICAL3	5.56e-05	191	95	5	f226fd69a26124ba98e4544f550b89a08e6a3708
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A NPTX1 RBFOX1 BSN CDH18	5.84e-05	193	95	5	5fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCell	(1)_T_cells-(1)_T_CD8_activated\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	FCRL3 HLA-DMA HLA-DQA1 CHST12 F2R	5.99e-05	194	95	5	e3f288b58525c1f34db4459d3e83e0df695adfc7
ToppCell	normal_Lymph_Node-T/NK_cells-Naive_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	FCRL3 HLA-DMA HLA-DQA1 CHST12 F2R	5.99e-05	194	95	5	72749ab1dd36a0d58624328961e1db08ccba2686
ToppCell	Control-CD8+_Tem\|Control / Disease condition and Cell class	HLA-DMA MYO6 HLA-DQA1 DUSP8 F2R	6.14e-05	195	95	5	7503b3e032f95b350a2782d28e4d412a8dc9ebcc
ToppCell	ILEUM-inflamed-(1)_T_cell-(1)_Cytotoxic_T_cells\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FCRL3 HLA-DMA HLA-DQA1 PZP F2R	6.29e-05	196	95	5	a8217c8e27027c0444ce072fe194404345c34022
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FCRL3 HLA-DMA SACS HLA-DQA1 MICAL3	6.29e-05	196	95	5	0175b097ad1338a07afebe3b5c7fd0bb0bb950f7
ToppCell	10x5'-blood-Lymphocytic_T_CD8\|blood / Manually curated celltypes from each tissue	FCRL3 MYO6 CHST12 F2R HSP90AA1	6.29e-05	196	95	5	2bf0f36af1d0934c03999dbbff3c51ae9432386d
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1A KCNH6 NPTX1 KCNH2 CDH18	6.60e-05	198	95	5	8f25e8dff42bad8e779ca618bdb1cb1610667962
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1A KCNH6 NPTX1 KCNH2 CDH18	6.60e-05	198	95	5	e3e0aa3ef20b2370f5b133048510677aaa562dfa
ToppCell	ASK454-Immune-B_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	HLA-DMA MYO6 TMEM259 HLA-DQA1 MECOM	6.75e-05	199	95	5	cbfabf8e895abe454606b990f99e3738f4263ffe
ToppCell	ASK454-Immune-B_cell\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	HLA-DMA MYO6 TMEM259 HLA-DQA1 MECOM	6.75e-05	199	95	5	b9b0ae81b9e7e35023c73d3b936e88167461ba54
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_ALM_Olfr111_Nxph1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NPTX1 GDPD2 F2R CDH18	1.35e-04	122	95	4	dba1c647172a11381efcb178a23808161908daa3
ToppCell	COVID-19_Mild-Neu_3\|World / 5 Neutrophil clusters in COVID-19 patients	TCAF2 MYO6 COQ8B RUFY4	1.35e-04	122	95	4	2aa9cfadab70312882ae679e3788fc7ab996c0f3
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1A PCDH11Y RBFOX1 CDH18	1.63e-04	128	95	4	91072ca56bce2c552a95edd67e17f43d8cc1de95
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1A PCDH11Y RBFOX1 CDH18	2.23e-04	139	95	4	64c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD8-Trm/em_CD8\|GI_small-bowel / Manually curated celltypes from each tissue	CAPN14 FCRL3 HLA-DQA1 PZP	2.56e-04	144	95	4	a4bb274d553c29c8299354de757ecc5634008c68
ToppCell	Mild/Remission-B_naive-13\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	HLA-DQA1 PCDH11Y ZBTB12 EPHX3	2.62e-04	145	95	4	7827aef87f834cd0d19780417757c9386e19b22e
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-IPC_like\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	NPTX1 MYO6 ELAVL2 CHST12	2.84e-04	148	95	4	a261c6d3d9cf0311c053fca66c37d39e66db6ad8
ToppCell	LPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAJB13 FBXO16 KIF6 ZBBX	2.84e-04	148	95	4	d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	NPTX1 MYO6 ELAVL2 CHST12	2.84e-04	148	95	4	c0237ba7d4040b6a497094b362dfb8b3a97a7d06
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SACS ABCB11 PZP RUFY4	2.84e-04	148	95	4	dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCell	LPS-antiTNF-Epithelial_airway-Ciliated_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAJB13 FBXO16 KIF6 ZBBX	2.84e-04	148	95	4	c8e93b87212f55774223caa385859c566fa1981f
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_D\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NPTX1 PXDN DHH ELAVL2	2.91e-04	149	95	4	3e05711ad4a8c2e6ebe6f36b1cef8b17ec2a1708
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8\|TCGA-Bladder / Sample_Type by Project: Shred V9	SLC9A2 CYP4F22 TMEM97 CRH	2.99e-04	150	95	4	1aa9320d97ff10994ea024751790524fe133aba9
ToppCell	droplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGFALS ABCB11 PZP SLC27A5	3.06e-04	151	95	4	cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CAPN14 FCRL3 HLA-DMA HLA-DQA1	3.30e-04	154	95	4	020697ae8463b18f9b4270c404f52ce4c0e90135
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGFALS ABCB11 PZP SLC27A5	3.46e-04	156	95	4	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	METTL1 INTS5 FCRL3 RBFOX1	3.64e-04	158	95	4	4d997efc36fd8946775fe74dd9ac9ccd5ade64ff
ToppCell	PND07-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BCO2 HLA-DMA HLA-DQA1 SDAD1	3.72e-04	159	95	4	a5fee9e7ee00c20a4ba30b0dfaf1189fb109a1af
ToppCell	E18.5-Immune-Immune_Myeloid-DC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BCO2 HLA-DMA HLA-DQA1 NFU1	3.81e-04	160	95	4	9f1fec2cf565193c73cc3c8a4f0476e57478e3b8
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_2\|368C / Donor, Lineage, Cell class and subclass (all cells)	HLA-DMA HLA-DQA1 KCNH2 SNX27	3.81e-04	160	95	4	ac3f56f8ab8efd11c4b4868a828db05c23ac762f
ToppCell	VE-CD8-CD4_Treg\|VE / Condition, Cell_class and T cell subcluster	FCRL3 PZP AKT1S1 SDAD1	3.90e-04	161	95	4	a114f4f75859d9ef900e5146686438d051241429
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMX3 HTR3E VRTN NRG2	3.90e-04	161	95	4	f5df8c6a340d5026726804b103e32137f363ca40
ToppCell	Severe-B_naive-11\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	FCRL3 HLA-DMA HLA-DQA1 MICAL3	3.90e-04	161	95	4	ad3b58e3a8b59a609c8d2d2690d15218d18eabbd
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-DC1\|bone_marrow / Manually curated celltypes from each tissue	HLA-DMA HLA-DQA1 ELAVL2 PLCD1	3.90e-04	161	95	4	2f068ee643de2f647c289779a6624265ab9a749b
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue-6\|TCGA-Colorectal / Sample_Type by Project: Shred V9	HTR3E ABCB11 GDPD2 PLCD1	4.00e-04	162	95	4	7f9385aa749bfb2fa9fee6939fe46d946bc21d31
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	DENND4A FCRL3 HLA-DMA HLA-DQA1	4.09e-04	163	95	4	6bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell	Ciliated_cells-B-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	DNAJB13 TMEM231 PZP ZBBX	4.19e-04	164	95	4	0e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCell	PND07-Immune-Immune_Myeloid-DC-cDC1\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BCO2 HLA-DMA HLA-DQA1 SDAD1	4.19e-04	164	95	4	662f74ad2656c0af158dbf9eb81d5bf70f54e529
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1A KCNH2 ELAVL2 CDH18	4.19e-04	164	95	4	be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_naive-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HLA-DMA HLA-DQA1 MECOM MICAL3	4.28e-04	165	95	4	8003fd2aa3f5c9d0e99054af4ad2d79a4a3c4829
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DPP7 HLA-DMA HLA-DQA1 DUSP8	4.28e-04	165	95	4	60b500eb2c10cccf309b8fb28a9119da22d6889c
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNH6 SACS HLA-DQA1 NRG2	4.28e-04	165	95	4	0c80abf13409767825ef8a507b498afafa7e89c5
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNH6 SACS HLA-DQA1 NRG2	4.28e-04	165	95	4	cced77f2d74b07010307d7f4788b8cf3fdaeb91a
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPTX1 PRR19 RBFOX1 NRG2	4.48e-04	167	95	4	3dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPTX1 PRR19 RBFOX1 NRG2	4.48e-04	167	95	4	95b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPTX1 PRR19 RBFOX1 NRG2	4.48e-04	167	95	4	9480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCAF2 OGT ABCE1 PCNX1	4.48e-04	167	95	4	ced6ed9b412739c6ced622523347c10295edbf53
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BCO2 HLA-DMA HLA-DQA1 NFU1	4.58e-04	168	95	4	93b7138f17aa14a6398c9b4ea7237781a0e19a66
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells\|GI_small-bowel / Manually curated celltypes from each tissue	CAPN14 HLA-DMA HLA-DQA1 ZBBX	4.58e-04	168	95	4	8e025bb0541746e232b77ac0e31412ae71420c47
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BCO2 HLA-DMA HLA-DQA1 NFU1	4.58e-04	168	95	4	e393553208617a023f1646169c892a87c95db3f5
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_B\|GI_small-bowel / Manually curated celltypes from each tissue	CAPN14 HLA-DMA HLA-DQA1 ZBBX	4.58e-04	168	95	4	5535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_naive\|lymph-node_spleen / Manually curated celltypes from each tissue	FCRL3 HLA-DMA HLA-DQA1 MICAL3	4.58e-04	168	95	4	494d5a11154ff22fedb25f4036d730cef376da60
ToppCell	Ionocyte-iono-1\|World / Class top	DENND4A AGL DUSP8 PZP	4.69e-04	169	95	4	4b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRPSAP2 FCRL3 HLA-DMA HLA-DQA1	4.69e-04	169	95	4	a34aff9257ae9746226ee7af595c4678a4b0c896
ToppCell	droplet-Lung-nan-18m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLA-DMA HLA-DQA1 SDAD1 FAM149A	4.69e-04	169	95	4	149a4f83da15bdeb170e980fb5b5b1af89ae07a6
ToppCell	droplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BCO2 HLA-DMA HLA-DQA1 FAM149A	4.69e-04	169	95	4	9c9bb1b32fc6e22359424a262178906c3954415d
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1A KCNH6 KCNH2 CDH18	4.69e-04	169	95	4	b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HLA-DMA HLA-DQA1 SDAD1 FAM149A	4.79e-04	170	95	4	bf589c4297ccc90e5f51e3d0fcc229548af4fcef
ToppCell	Severe-B_naive-11\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	FCRL3 HLA-DMA HLA-DQA1 MICAL3	4.90e-04	171	95	4	7c2699f19ca38414447a286f7658f507882d57c2
ToppCell	COVID-19-Heart-T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1A RBFOX1 EPB42 CDH18	4.90e-04	171	95	4	b2e753e811a7639956994609f73efcdb62d04f82
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRPSAP2 BCO2 HLA-DQA1 BSN	5.01e-04	172	95	4	76c06a968d3333441eed103abef1e636a1c3e7a1
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FCRL3 HLA-DMA HLA-DQA1 MICAL3	5.01e-04	172	95	4	62ed3b70fa1f6c84ea80ff00f60d2562be292e9d
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCO2 HLA-DMA HLA-DQA1 FAM149A	5.01e-04	172	95	4	a5344760b10ecdc0101f78b93b8fc0f8107068c5
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue\|TCGA-Colorectal / Sample_Type by Project: Shred V9	HTR3E ABCB11 GDPD2 PLCD1	5.01e-04	172	95	4	94842346c84542a5243bd765e49f4af8bc5182db
Disease	short QT syndrome (implicated_via_orthology)	KCNH6 KCNH2	2.88e-05	3	92	2	DOID:0050793 (implicated_via_orthology)
Disease	wheat allergic reaction	HLA-DQA1 RBFOX1	5.75e-05	4	92	2	EFO_1001243
Disease	Delayed Puberty	IGFALS CRH	2.00e-04	7	92	2	C0034012
Disease	PAX-interacting protein 1 measurement	HLA-DQA1 TMEM97	2.66e-04	8	92	2	EFO_0801868
Disease	long QT syndrome (implicated_via_orthology)	KCNH6 KCNH2	4.26e-04	10	92	2	DOID:2843 (implicated_via_orthology)
Disease	C-C motif chemokine 19 measurement	HLA-DQA1 BSN	8.54e-04	14	92	2	EFO_0008047
Disease	lower body strength measurement	HMX3 RBFOX1	1.12e-03	16	92	2	EFO_0007999
Disease	hearing loss	MYO6 UTP15 HLA-DQA1	1.22e-03	67	92	3	EFO_0004238
Disease	anti-anoctamin 2 antibody measurement	HLA-DQA1 RBFOX1	1.27e-03	17	92	2	EFO_0010150
Disease	joint damage measurement	HLA-DQA1 RBFOX1 MECOM	1.27e-03	68	92	3	EFO_0005413
Disease	epilepsy (implicated_via_orthology)	CACNA1A KCNH6 KCNH2 BSN	1.72e-03	163	92	4	DOID:1826 (implicated_via_orthology)
Disease	left ventricular structural measurement	PXDN RBFOX1 MECOM	2.66e-03	88	92	3	EFO_0008205
Disease	smoking status measurement, chronic obstructive pulmonary disease	HLA-DQA1 MECOM MICAL3	2.66e-03	88	92	3	EFO_0000341, EFO_0006527
Disease	pulmonary embolism	OR6S1 RBFOX1	2.75e-03	25	92	2	EFO_0003827

Protein segments in the cluster

Peptide	Gene	Start	Entry
DRFLARENFPNVLQP	nan	81	A8MZ25
VQPNAPRNNVLRYFD	CACNA1A	1266	O00555
NFERNPPENTFLRLT	EPB42	551	P16452
FGDLPRPRLNTSDFQ	AKT1S1	236	Q96B36
DPTALNSVFNRKPFR	HTR3E	41	A5X5Y0
VKDRRPSISPNFNFL	DUSP8	276	Q13202
ISAARFFQLLDRQPP	ABCB11	1046	O95342
FFQLLDRQPPISVYN	ABCB11	1051	O95342
ALRDFALQNPSAVPR	IGFALS	546	P35858
PFAPLNFRINSRNLS	DOT1L	271	Q8TEK3
SFPRRFVLPLNVSLN	BCO2	406	Q9BYV7
LPVLRQFRFDPQFAL	HLA-DQA1	71	P01909
FFQRNTPLSQPDRFL	CAPN14	441	A8MX76
LQPFPRAEQRNFLRS	ETV4	151	P43268
PVLRNNLFERPEGFL	DENND4A	701	Q7Z401
DENFRPRNELIPLIY	PZP	151	P20742
FNFRAPPNALPENLL	MECOM	891	Q03112
DNRPGDKFQLTFPLR	NPTX1	221	Q15818
NFVVRYRPDEQPSLR	PLOD3	651	O60568
IQRNQPQRPESFLFR	LRCH3	601	Q96II8
DPVTRYPNINVNFLR	MICAL3	466	Q7RTP6
PFQLPFRPQDDLLAR	KMT2C	3946	Q8NEZ4
PAAAFRSPLARQLFR	NFU1	91	Q9UMS0
PLQRRPAYFADRTQN	FAM149A	556	A5PLN7
RNKLPFLPSEFRNLS	LRR1	281	Q96L50
LAFPRFEIPAQRFAL	HMX3	91	A6NHT5
FHQIPNPLRQRLEEY	KCNH2	686	Q12809
IPNPLRQRLEEYFQH	KCNH6	541	Q9H252
RYNLPNQVAPLARRD	BSN	1801	Q9UPA5
FFEGLLPRDNPRNTR	CWC22	611	Q9HCG8
LPRDNPRNTRFAINF	CWC22	616	Q9HCG8
FPLYQQRRGLDPVSE	PCNX1	301	Q96RV3
VPLERNQRYIFFLEP	NRG2	186	O14511
NQRYIFFLEPTEQPL	NRG2	191	O14511
RYILNVTPNLPNFFE	DUSP9	231	Q99956
QSLQPDPAARYRNVL	SLC25A28	101	Q96A46
REFRQSQSPPFRLGN	KIF6	501	Q6ZMV9
RTERPQFLNLPYQDL	GDPD2	416	Q9HCC8
SSRPELLQPLNFVRF	GLT8D2	126	Q9H1C3
RPSPEQATANFFRVL	CRH	101	P06850
NRENFSPERFLPLNI	RBBP6	856	Q7Z6E9
QPTPFVSLFFQRLLR	PLOD1	296	Q02809
ATLDPRSFLLRNPND	F2R	36	P25116
AFLRDPNGTFNPRAL	PLCD1	606	P51178
PLLNPFIYALRNEQV	OR6S1	286	Q8NH40
QLEITFRRDPNNYRP	ABCE1	561	P61221
SERFRDLVPNYNPDI	DHH	71	O43323
RPNFNTPQALRFEEP	GON4L	621	Q3T8J9
FDFSQNTRVPRLPEF	HLA-DMA	71	P28067
NFRQLLANDPFFRVP	COQ8B	296	Q96D53
YPGPLAQQAQRFRLD	ELAVL2	226	Q12926
YRNLFRNFPLEPQEL	EPHX3	281	Q9H6B9
SPQRPDVQLQFSLFR	FCRL3	216	Q96P31
NLNPNPLINVRDRLF	TMEM259	31	Q4ZIN3
PRFNFFLDERLPVNP	CDH18	521	Q13634
PRFRRENDNLFFVNP	DNAJB13	221	P59910
FNIPVDNLRASPFLL	PRPSAP2	156	O60256
LFVPRRAPFDLFENR	HSP90AA1	341	P07900
PTDIIRFNYLDNRDP	FBXO16	226	Q8IX29
FRFPLRLQPSQLSSN	SACS	271	Q9NZJ4
QRDFPRSFLLDLPNF	ISM1	96	B1AKI9
RDPAAFAPILNFLRT	KCTD3	66	Q9Y597
RFDPDNPQQRSPLAY	CYP4F22	451	Q6NT55
APDPGFQERFFQQRL	DPP7	26	Q9UHL4
ARNELFALRPAPIQA	OGT	646	O15294
IPFRLRPVFSNQFLL	PCDH11Y	436	Q9BZA8
ALRRRGFPPEAINNF	QARS1	521	P47897
VLNFLIRNLSQPRFA	UTP15	421	Q8TED0
VSNIPFRFRDPDLRQ	RBFOX1	121	Q9NWB1
PLRENSFGSPLEFRN	SRRM2	1321	Q9UQ35
QALSNVPPLRNYFLE	USP39	241	Q53GS9
QAVARLAAEPFPFRR	TCAF2	696	A6NFQ2
LPRSQQQRHLPFFLE	RUFY4	236	Q6ZNE9
YPFLQRFLQPHQREV	SDAD1	336	Q9NVU7
FRSLFPLENLQPDFN	SLF2	866	Q8IX21
LQPPFTARFLRNLAL	INTS5	566	Q6P9B9
LRRSPFLQVFNNSPD	SEC23B	586	Q15437
LQVDRQLRFPPSYRN	CHST12	356	Q9NRB3
PQVFNPLRFSRENSE	CYP4Z1	421	Q86W10
NRPTDPASLAVFRFL	GGCX	56	P38435
PFLRDQFLLNPSSEL	ZBTB12	56	Q9Y330
AFLADSQPPNRRALA	YIPF6	201	Q96EC8
PNFTNQLLRRFIPTS	TRAPPC11	1101	Q7Z392
NLQPRARRFLPEQFS	SLC9A2	706	Q9UBY0
SLPQAFPRRNLIQDA	PRR19	156	A6NJB7
PLFVLDNRAQSFRPL	SLC27A5	661	Q9Y2P5
AERNRYFISLQQPPA	RNF25	256	Q96BH1
LVNPLLYRLDENFQP	PXDN	1076	Q92626
AFVNLNNIPDYRLRP	XPO5	876	Q9HAV4
LLYEANLPENFRRPQ	SMAP1	96	Q8IYB5
NLKREFANFTFPRLP	SNX27	206	Q96L92
QAVLPRELYPVEFRN	TMEM97	31	Q5BJF2
FPAFNRLQGDRLRVP	TMEM231	86	Q9H6L2
PLQQFLQRFPEISRS	VRTN	331	Q9H8Y1
APDIRNRFPNFLGII	UBQLN3	326	Q9H347
NFPAIFRRIQDPVLQ	METTL1	251	Q9UBP6
RFFIFDTNERLNLLP	ZBBX	596	A8MT70
ANQLELNPDFSRPNR	AGL	176	P35573
QQRFFRIPFIRPADQ	MYO6	1176	Q9UM54