Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	soluble NSF attachment protein activity	NAPB NAPA	5.48e-05	3	86	2	GO:0005483
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA13 ABCD2 TAP2 ABCA9	5.86e-05	49	86	4	GO:0140359
GeneOntologyMolecularFunction	narrow pore channel activity	NALCN KCNK13 KCNK12	7.11e-05	19	86	3	GO:0022842
GeneOntologyMolecularFunction	leak channel activity	NALCN KCNK13 KCNK12	7.11e-05	19	86	3	GO:0022840
GeneOntologyMolecularFunction	monoatomic cation channel activity	TRPM6 CACNA1C CACNA1S NALCN TRPM7 KCNK13 KCNK12 MCOLN3	1.16e-04	343	86	8	GO:0005261
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	TRPM6 TRIO TRPM7 PDGFRB PIK3R1 LRRK2 CCND1 STK32C COASY PEAK1 MAP3K4	2.27e-04	709	86	11	GO:0016773
GeneOntologyMolecularFunction	calcium channel activity	TRPM6 CACNA1C CACNA1S TRPM7 MCOLN3	2.39e-04	129	86	5	GO:0005262
GeneOntologyMolecularFunction	kinase activity	TRPM6 TRIO TRPM7 PDGFRB PIK3R1 LRRK2 CCND1 STK32C COASY PEAK1 MAP3K4	4.29e-04	764	86	11	GO:0016301
GeneOntologyMolecularFunction	calmodulin binding	CACNA1C CACNA1S PDE1A PIK3R1 ASPM UNC13A	4.77e-04	230	86	6	GO:0005516
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	TRPM6 CACNA1C CACNA1S TRPM7 MCOLN3	4.93e-04	151	86	5	GO:0015085
GeneOntologyMolecularFunction	syntaxin binding	NAPB LRRK2 NAPA UNC13A	5.44e-04	87	86	4	GO:0019905
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	TRPM6 TRIO TRPM7 PDGFRB PIK3R1 LRRK2 CCND1 STK32C COASY PEAK1 MAP3K4 DNTT	6.67e-04	938	86	12	GO:0016772
GeneOntologyMolecularFunction	unmethylated CpG binding	KMT2A FBXL19	8.07e-04	10	86	2	GO:0045322
GeneOntologyMolecularFunction	monoatomic ion channel activity	TRPM6 CACNA1C CACNA1S NALCN TRPM7 KCNK13 KCNK12 MCOLN3	8.12e-04	459	86	8	GO:0005216
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	TRPM6 CACNA1C CACNA1S NALCN TRPM7 KCNK13 KCNK12 MCOLN3	8.83e-04	465	86	8	GO:0046873
GeneOntologyMolecularFunction	protein kinase activity	TRPM6 TRIO TRPM7 PDGFRB LRRK2 CCND1 STK32C PEAK1 MAP3K4	1.11e-03	600	86	9	GO:0004672
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA13 ABCD2 TAP2 ABCA9	1.26e-03	109	86	4	GO:0042626
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1C CACNA1S	1.61e-03	14	86	2	GO:0008331
GeneOntologyMolecularFunction	channel activity	TRPM6 CACNA1C CACNA1S NALCN TRPM7 KCNK13 KCNK12 MCOLN3	1.91e-03	525	86	8	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	TRPM6 CACNA1C CACNA1S NALCN TRPM7 KCNK13 KCNK12 MCOLN3	1.93e-03	526	86	8	GO:0022803
GeneOntologyMolecularFunction	potassium ion leak channel activity	KCNK13 KCNK12	2.12e-03	16	86	2	GO:0022841
GeneOntologyMolecularFunction	platelet-derived growth factor receptor binding	PDGFRB PIK3R1	2.39e-03	17	86	2	GO:0005161
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase regulator activity	WDR91 PIK3R1	2.68e-03	18	86	2	GO:0035014
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH10 DNAH5	2.68e-03	18	86	2	GO:0008569
GeneOntologyMolecularFunction	SNARE binding	NAPB LRRK2 NAPA UNC13A	2.84e-03	136	86	4	GO:0000149
GeneOntologyMolecularFunction	ATP hydrolysis activity	DNAH10 ABCA13 ABCD2 DNAH5 TAP2 ABCA9 DHX9	2.93e-03	441	86	7	GO:0016887
GeneOntologyMolecularFunction	pyrophosphatase activity	DNAH10 ABCA13 LRRK2 ENPP5 ABCD2 RAB2A DNAH5 TAP2 ABCA9 DHX9	3.21e-03	839	86	10	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DNAH10 ABCA13 LRRK2 ENPP5 ABCD2 RAB2A DNAH5 TAP2 ABCA9 DHX9	3.24e-03	840	86	10	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DNAH10 ABCA13 LRRK2 ENPP5 ABCD2 RAB2A DNAH5 TAP2 ABCA9 DHX9	3.24e-03	840	86	10	GO:0016818
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	CCDC124 NAPB PIK3R1 SYNE2 LRRK2 MED12L NAPA CCND1 FBXL19 BCOR DHX9 FAN1	3.98e-03	1160	86	12	GO:0030674
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1C CACNA1S KCNK13 KCNK12	4.23e-03	152	86	4	GO:0022843
GeneOntologyMolecularFunction	transmembrane transporter activity	TRPM6 CACNA1C CACNA1S NALCN TRPM7 ABCA13 KCNK13 KCNK12 ABCD2 TAP2 ABCA9 MCOLN3	4.56e-03	1180	86	12	GO:0022857
GeneOntologyMolecularFunction	actin binding	TRPM7 SYNE2 VASH2 LRRK2 AFDN CLASP2 PPP1R42	4.61e-03	479	86	7	GO:0003779
GeneOntologyMolecularFunction	syntaxin-1 binding	LRRK2 UNC13A	4.76e-03	24	86	2	GO:0017075
GeneOntologyMolecularFunction	protein serine kinase activity	TRPM6 TRIO TRPM7 LRRK2 STK32C MAP3K4	4.81e-03	363	86	6	GO:0106310
GeneOntologyBiologicalProcess	regulation of synaptic vesicle priming	NAPB NAPA UNC13A	2.46e-05	14	86	3	GO:0010807
GeneOntologyBiologicalProcess	positive regulation of mini excitatory postsynaptic potential	ADRB2 AFDN	5.14e-05	3	86	2	GO:0061885
GeneOntologyBiologicalProcess	SNARE complex disassembly	NAPB NAPA	5.14e-05	3	86	2	GO:0035494
GeneOntologyCellularComponent	synaptobrevin 2-SNAP-25-syntaxin-1a complex	NAPB NAPA	1.62e-04	5	85	2	GO:0070044
GeneOntologyCellularComponent	presynaptic active zone	TRIO NAPB NAPA AFDN UNC13A	2.77e-04	141	85	5	GO:0048786
MousePheno	abnormal CNS glial cell morphology	ADRB2 SYNE2 LRRK2 ASPM AIPL1 KCNK13 ABCD2 EPG5	2.84e-05	272	63	8	MP:0000952
MousePheno	atrioventricular septal defect	PSME4 PDGFRB PDS5A CPLANE1 DNAH5	3.71e-05	84	63	5	MP:0010412
MousePheno	abnormal atrioventricular septum morphology	PSME4 PDGFRB PDS5A CPLANE1 DNAH5	4.40e-05	87	63	5	MP:0010592
MousePheno	increased retina apoptosis	ADRB2 PDGFRB SYNE2 EPG5	4.86e-05	45	63	4	MP:0030005
MousePheno	abnormal Muller cell morphology	ADRB2 SYNE2 AIPL1	9.42e-05	20	63	3	MP:0005547
MousePheno	abnormal glial cell morphology	ADRB2 SYNE2 LRRK2 ASPM AIPL1 KCNK13 ABCD2 EPG5	1.51e-04	345	63	8	MP:0003634
MousePheno	right aortic arch	PSME4 PDGFRB CPLANE1 DNAH5	1.51e-04	60	63	4	MP:0004158
MousePheno	abnormal retina apoptosis	ADRB2 PDGFRB SYNE2 EPG5	1.72e-04	62	63	4	MP:0006072
Domain	ARM-type_fold	RALGAPA1 PSME4 NBEAL1 ELMO2 MROH2B LRRK2 INTS1 ASPM PDS5A CLASP2	2.85e-06	339	84	10	IPR016024
Domain	Ion_trans_dom	TRPM6 CACNA1C CACNA1S NALCN TRPM7 MCOLN3	1.25e-05	114	84	6	IPR005821
Domain	Ion_trans	TRPM6 CACNA1C CACNA1S NALCN TRPM7 MCOLN3	1.25e-05	114	84	6	PF00520
Domain	2pore_dom_K_chnl_THIK	KCNK13 KCNK12	2.00e-05	2	84	2	IPR005410
Domain	AAA+_ATPase	DNAH10 ABCA13 ABCD2 DNAH5 TAP2 ABCA9	4.69e-05	144	84	6	IPR003593
Domain	AAA	DNAH10 ABCA13 ABCD2 DNAH5 TAP2 ABCA9	4.69e-05	144	84	6	SM00382
Domain	NSF_attach	NAPB NAPA	5.98e-05	3	84	2	IPR000744
Domain	-	PSME4 ELMO2 MROH2B LRRK2 ASPM PDS5A CLASP2	6.36e-05	222	84	7	1.25.10.10
Domain	ABC_tran	ABCA13 ABCD2 TAP2 ABCA9	6.37e-05	48	84	4	PF00005
Domain	ABC_TRANSPORTER_2	ABCA13 ABCD2 TAP2 ABCA9	6.37e-05	48	84	4	PS50893
Domain	ABC_TRANSPORTER_1	ABCA13 ABCD2 TAP2 ABCA9	6.91e-05	49	84	4	PS00211
Domain	ABC_transporter-like	ABCA13 ABCD2 TAP2 ABCA9	7.49e-05	50	84	4	IPR003439
Domain	TRPM_tetra	TRPM6 TRPM7	1.19e-04	4	84	2	IPR032415
Domain	TRPM_tetra	TRPM6 TRPM7	1.19e-04	4	84	2	PF16519
Domain	VDCC_L_a1su	CACNA1C CACNA1S	1.19e-04	4	84	2	IPR005446
Domain	ARM-like	PSME4 ELMO2 MROH2B LRRK2 ASPM PDS5A CLASP2	2.14e-04	270	84	7	IPR011989
Domain	HEAT_REPEAT	PSME4 MROH2B PDS5A CLASP2	2.78e-04	70	84	4	PS50077
Domain	Spectrin_repeat	TRIO SYNE2 MCF2	2.95e-04	29	84	3	IPR002017
Domain	Alpha_kinase	TRPM6 TRPM7	2.96e-04	6	84	2	PF02816
Domain	ALPHA_KINASE	TRPM6 TRPM7	2.96e-04	6	84	2	PS51158
Domain	Alpha_kinase	TRPM6 TRPM7	2.96e-04	6	84	2	SM00811
Domain	MHCK_EF2_kinase	TRPM6 TRPM7	2.96e-04	6	84	2	IPR004166
Domain	P-loop_NTPase	DNAH10 ABCA13 LRRK2 ASPM HS3ST5 COASY ABCD2 RAB2A DNAH5 TAP2 ABCA9 DHX9	3.95e-04	848	84	12	IPR027417
Domain	Spectrin/alpha-actinin	TRIO SYNE2 MCF2	3.96e-04	32	84	3	IPR018159
Domain	SPEC	TRIO SYNE2 MCF2	3.96e-04	32	84	3	SM00150
Domain	VDCC_a1su_IQ	CACNA1C CACNA1S	4.14e-04	7	84	2	IPR014873
Domain	GPHH	CACNA1C CACNA1S	4.14e-04	7	84	2	PF16905
Domain	GPHH_dom	CACNA1C CACNA1S	4.14e-04	7	84	2	IPR031649
Domain	Ca_chan_IQ	CACNA1C CACNA1S	4.14e-04	7	84	2	SM01062
Domain	Ca_chan_IQ	CACNA1C CACNA1S	4.14e-04	7	84	2	PF08763
Domain	-	DNAH10 ABCA13 LRRK2 HS3ST5 COASY ABCD2 RAB2A DNAH5 TAP2 ABCA9 DHX9	5.00e-04	746	84	11	3.40.50.300
Domain	DHC_N1	DNAH10 DNAH5	5.50e-04	8	84	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH10 DNAH5	5.50e-04	8	84	2	IPR013594
Domain	Leu-rich_rpt_4	LRRK2 PPP1R42	8.79e-04	10	84	2	IPR025875
Domain	LRR_4	LRRK2 PPP1R42	8.79e-04	10	84	2	PF12799
Domain	VDCCAlpha1	CACNA1C CACNA1S	8.79e-04	10	84	2	IPR002077
Domain	Znf_CXXC	KMT2A FBXL19	1.07e-03	11	84	2	IPR002857
Domain	ZF_CXXC	KMT2A FBXL19	1.07e-03	11	84	2	PS51058
Domain	zf-CXXC	KMT2A FBXL19	1.07e-03	11	84	2	PF02008
Domain	ABC_A	ABCA13 ABCA9	1.28e-03	12	84	2	IPR026082
Domain	Dynein_heavy_chain_D4_dom	DNAH10 DNAH5	1.76e-03	14	84	2	IPR024317
Domain	Dynein_HC_stalk	DNAH10 DNAH5	1.76e-03	14	84	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH10 DNAH5	1.76e-03	14	84	2	IPR013602
Domain	DHC_N2	DNAH10 DNAH5	1.76e-03	14	84	2	PF08393
Domain	MT	DNAH10 DNAH5	1.76e-03	14	84	2	PF12777
Domain	AAA_8	DNAH10 DNAH5	1.76e-03	14	84	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH10 DNAH5	1.76e-03	14	84	2	IPR011704
Domain	AAA_5	DNAH10 DNAH5	1.76e-03	14	84	2	PF07728
Domain	DHC_fam	DNAH10 DNAH5	2.02e-03	15	84	2	IPR026983
Domain	Dynein_heavy_dom	DNAH10 DNAH5	2.02e-03	15	84	2	IPR004273
Domain	2pore_dom_K_chnl	KCNK13 KCNK12	2.02e-03	15	84	2	IPR003280
Domain	Dynein_heavy	DNAH10 DNAH5	2.02e-03	15	84	2	PF03028
Domain	Channel_four-helix_dom	CACNA1C CACNA1S NALCN	2.16e-03	57	84	3	IPR027359
Domain	-	CACNA1C CACNA1S NALCN	2.16e-03	57	84	3	1.20.120.350
Domain	Kinase-like_dom	TRPM6 TRIO TRPM7 PDGFRB LRRK2 STK32C PEAK1 MAP3K4	3.01e-03	542	84	8	IPR011009
Domain	BRCT	LIG4 DNTT	3.25e-03	19	84	2	PF00533
Domain	K_chnl_dom	KCNK13 KCNK12	3.97e-03	21	84	2	IPR013099
Domain	Ion_trans_2	KCNK13 KCNK12	3.97e-03	21	84	2	PF07885
Domain	BRCT	LIG4 DNTT	4.36e-03	22	84	2	SM00292
Domain	Spectrin	TRIO SYNE2	4.76e-03	23	84	2	PF00435
Domain	-	LIG4 DNTT	4.76e-03	23	84	2	3.40.50.10190
Domain	BRCT	LIG4 DNTT	6.06e-03	26	84	2	PS50172
Pubmed	Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.	ELMO2 PIK3R1 AFDN CLASP2 PEAK1 PTPN18	2.42e-07	103	87	6	21706016
Pubmed	SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming.	NAPB NAPA UNC13A	1.79e-06	10	87	3	21040848
Pubmed	Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.	ELMO2 EML4 SYNE2 CLASP2	2.26e-06	37	87	4	27565344
Pubmed	Structure of a specific peptide complex of the carboxy-terminal SH2 domain from the p85 alpha subunit of phosphatidylinositol 3-kinase.	PDGFRB PIK3R1	6.19e-06	2	87	2	8670861
Pubmed	Temporal expression of calcium channel subunits in satellite cells and bone marrow mesenchymal cells.	CACNA1C CACNA1S	6.19e-06	2	87	2	25277766
Pubmed	Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7.	TRPM6 TRPM7	6.19e-06	2	87	2	16636202
Pubmed	Genes for beta 2-adrenergic receptor and platelet-derived growth factor receptor map to mouse chromosome 18.	ADRB2 PDGFRB	6.19e-06	2	87	2	2569767
Pubmed	NMR trial models: experiences with the colicin immunity protein Im7 and the p85alpha C-terminal SH2-peptide complex.	PDGFRB PIK3R1	6.19e-06	2	87	2	11567151
Pubmed	A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice.	CACNA1C CACNA1S	6.19e-06	2	87	2	1281468
Pubmed	TRPM6 kinase activity regulates TRPM7 trafficking and inhibits cellular growth under hypomagnesic conditions.	TRPM6 TRPM7	6.19e-06	2	87	2	24858416
Pubmed	Phosphorylation of Cav1.2 on S1928 uncouples the L-type Ca2+ channel from the β2 adrenergic receptor.	CACNA1C ADRB2	6.19e-06	2	87	2	27103070
Pubmed	Cellular localization of THIK-1 (K(2P)13.1) and THIK-2 (K(2P)12.1) K channels in the mammalian kidney.	KCNK13 KCNK12	6.19e-06	2	87	2	18209473
Pubmed	Common genetic variants of the ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7), magnesium intake, and risk of type 2 diabetes in women.	TRPM6 TRPM7	6.19e-06	2	87	2	19149903
Pubmed	Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.	TRPM6 TRPM7	6.19e-06	2	87	2	18365021
Pubmed	Interaction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: structural features and analysis of conformational changes.	PDGFRB PIK3R1	6.19e-06	2	87	2	1330535
Pubmed	Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia.	TRPM6 TRPM7	6.19e-06	2	87	2	14976260
Pubmed	High content screening for inhibitors of protein interactions and post-translational modifications in primary cells by proximity ligation.	PDGFRB PIK3R1	6.19e-06	2	87	2	19864249
Pubmed	Proteasome activators, PA28γ and PA200, play indispensable roles in male fertility.	PSME4 PSME3	6.19e-06	2	87	2	27003159
Pubmed	Dysregulation of renal transient receptor potential melastatin 6/7 but not paracellin-1 in aldosterone-induced hypertension and kidney damage in a model of hereditary hypomagnesemia.	TRPM6 TRPM7	6.19e-06	2	87	2	21602712
Pubmed	Tandem pore domain halothane-inhibited K+ channel subunits THIK1 and THIK2 assemble and form active channels.	KCNK13 KCNK12	6.19e-06	2	87	2	25148687
Pubmed	Differential mRNA expression and glucocorticoid-mediated regulation of TRPM6 and TRPM7 in the heart and kidney throughout murine pregnancy and development.	TRPM6 TRPM7	6.19e-06	2	87	2	25692682
Pubmed	The TRPM6 kinase domain determines the Mg·ATP sensitivity of TRPM7/M6 heteromeric ion channels.	TRPM6 TRPM7	6.19e-06	2	87	2	24385424
Pubmed	Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor.	PDGFRB PIK3R1	6.19e-06	2	87	2	7692233
Pubmed	Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal.	PDGFRB PIK3R1	6.19e-06	2	87	2	7536927
Pubmed	The channel kinases TRPM6 and TRPM7 are functionally nonredundant.	TRPM6 TRPM7	6.19e-06	2	87	2	16150690
Pubmed	TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg2+ and Mg·ATP.	TRPM6 TRPM7	6.19e-06	2	87	2	28821869
Pubmed	Recent developments in intestinal magnesium absorption.	TRPM6 TRPM7	6.19e-06	2	87	2	18301276
Pubmed	The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC.	TRPM6 TRPM7	6.19e-06	2	87	2	18675813
Pubmed	CoA synthase is in complex with p85alphaPI3K and affects PI3K signaling pathway.	PIK3R1 COASY	6.19e-06	2	87	2	19482007
Pubmed	Dual specificity of Src homology 2 domains for phosphotyrosine peptide ligands.	PDGFRB PIK3R1	6.19e-06	2	87	2	9153411
Pubmed	Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression.	CACNA1C STRIP2	6.19e-06	2	87	2	27122098
Pubmed	Mass Spectrometric Analysis of TRPM6 and TRPM7 Phosphorylation Reveals Regulatory Mechanisms of the Channel-Kinases.	TRPM6 TRPM7	6.19e-06	2	87	2	28220887
Pubmed	Identification and characterization of FBXL19 gene in silico.	KMT2A FBXL19	6.19e-06	2	87	2	15547684
Pubmed	Role of Cyclin D1 and BCOR Immunohistochemistry in Differentiating Clear Cell Sarcoma of Kidney From its Mimics.	CCND1 BCOR	6.19e-06	2	87	2	34673711
Pubmed	Tyrosine phosphorylation-dependent yeast two-hybrid system for the identification of the SH2 domain-binding proteins.	PDGFRB PIK3R1	6.19e-06	2	87	2	11710529
Pubmed	Transient receptor potential melastatin 6 and 7 channels, magnesium transport, and vascular biology: implications in hypertension.	TRPM6 TRPM7	6.19e-06	2	87	2	18192217
Pubmed	THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels.	KCNK13 KCNK12	6.19e-06	2	87	2	11060316
Pubmed	Endogenous cardiac Ca2+ channels do not overcome the E-C coupling defect in immortalized dysgenic muscle cells: evidence for a missing link.	CACNA1C CACNA1S	6.19e-06	2	87	2	7635187
Pubmed	Magnesium homeostasis in colon carcinoma LoVo cells sensitive or resistant to doxorubicin.	TRPM6 TRPM7	6.19e-06	2	87	2	26563869
Pubmed	PI3K is involved in PDGF-beta receptor upregulation post-PDGF-BB treatment in mouse HSC.	PDGFRB PIK3R1	6.19e-06	2	87	2	16990448
Pubmed	The Different Roles of The Channel-Kinases TRPM6 and TRPM7.	TRPM6 TRPM7	6.19e-06	2	87	2	26179995
Pubmed	Essential role for TRPM6 in epithelial magnesium transport and body magnesium homeostasis.	TRPM6 TRPM7	6.19e-06	2	87	2	16075242
Pubmed	MLL-AF6 fusion oncogene sequesters AF6 into the nucleus to trigger RAS activation in myeloid leukemia.	KMT2A AFDN	6.19e-06	2	87	2	24695851
Pubmed	Evidence for the expression of TRPM6 and TRPM7 in cardiomyocytes from all four chamber walls of the human heart.	TRPM6 TRPM7	6.19e-06	2	87	2	34326388
Pubmed	Structure-activity studies of phosphorylated peptide inhibitors of the association of phosphatidylinositol 3-kinase with PDGF-beta receptor.	PDGFRB PIK3R1	6.19e-06	2	87	2	8564419
Pubmed	Regulation of the two-pore domain potassium channel, THIK-1 and THIK-2, by G protein coupled receptors.	KCNK13 KCNK12	6.19e-06	2	87	2	37099539
Pubmed	TRPM6 is Essential for Magnesium Uptake and Epithelial Cell Function in the Colon.	TRPM6 TRPM7	6.19e-06	2	87	2	29912157
Pubmed	Magnesium and its transporters in cancer: a novel paradigm in tumour development.	TRPM6 TRPM7	6.19e-06	2	87	2	22671428
Pubmed	Gene variation of the transient receptor potential cation channel, subfamily M, members 6 (TRPM6) and 7 (TRPM7), and type 2 diabetes mellitus: a case-control study.	TRPM6 TRPM7	6.19e-06	2	87	2	20875900
Pubmed	Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.	PSME4 FAM78B AIPL1 PDS5A AFDN	1.33e-05	120	87	5	21697133
Pubmed	SNAP family of NSF attachment proteins includes a brain-specific isoform.	NAPB NAPA	1.85e-05	3	87	2	8455721
Pubmed	Sorcin associates with the pore-forming subunit of voltage-dependent L-type Ca2+ channels.	CACNA1C CACNA1S	1.85e-05	3	87	2	9668070
Pubmed	Localization of cardiac L-type Ca(2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulation.	CACNA1C ADRB2	1.85e-05	3	87	2	16648270
Pubmed	β2-adrenergic receptor-coupled phosphoinositide 3-kinase constrains cAMP-dependent increases in cardiac inotropy through phosphodiesterase 4 activation.	ADRB2 PIK3R1	1.85e-05	3	87	2	20705779
Pubmed	A new beat for the SNARE drum.	NAPB NAPA	1.85e-05	3	87	2	9695844
Pubmed	The Promoter-Associated Noncoding RNA pncCCND1_B Assembles a Protein-RNA Complex to Regulate Cyclin D1 Transcription in Ewing Sarcoma.	CCND1 DHX9	1.85e-05	3	87	2	31072811
Pubmed	Specific phosphopeptide binding regulates a conformational change in the PI 3-kinase SH2 domain associated with enzyme activation.	PDGFRB PIK3R1	1.85e-05	3	87	2	8382612
Pubmed	Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).	CACNA1C CACNA1S	1.85e-05	3	87	2	17767505
Pubmed	SHP-1 associates with both platelet-derived growth factor receptor and the p85 subunit of phosphatidylinositol 3-kinase.	PDGFRB PIK3R1	1.85e-05	3	87	2	9452499
Pubmed	Construction of an SH2 domain-binding site with mixed specificity.	PDGFRB PIK3R1	1.85e-05	3	87	2	7876130
Pubmed	Triad proteins and intracellular Ca2+ transients during development of human skeletal muscle cells in aneural and innervated cultures.	CACNA1C CACNA1S	1.85e-05	3	87	2	11206130
Pubmed	N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation.	TRPM6 TRPM7	1.85e-05	3	87	2	25277194
Pubmed	Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.	CACNA1C CACNA1S	1.85e-05	3	87	2	2173707
Pubmed	A macromolecular trafficking complex composed of β₂-adrenergic receptors, A-Kinase Anchoring Proteins and L-type calcium channels.	CACNA1C ADRB2	1.85e-05	3	87	2	23557075
Pubmed	mRNA for cardiac calcium channel is expressed during development of skeletal muscle.	CACNA1C CACNA1S	1.85e-05	3	87	2	8381753
Pubmed	A photoaffinity scan maps regions of the p85 SH2 domain involved in phosphoprotein binding.	PDGFRB PIK3R1	1.85e-05	3	87	2	7680644
Pubmed	Regulation of platelet-derived growth factor receptor activation by afadin through SHP-2: implications for cellular morphology.	PDGFRB AFDN	1.85e-05	3	87	2	17971444
Pubmed	Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo.	PDGFRB PIK3R1	1.85e-05	3	87	2	1314164
Pubmed	The inositol polyphosphate 4-phosphatase forms a complex with phosphatidylinositol 3-kinase in human platelet cytosol.	PIK3R1 INPP4B	1.85e-05	3	87	2	10097090
Pubmed	Interactions between SH2 domains and tyrosine-phosphorylated platelet-derived growth factor beta-receptor sequences: analysis of kinetic parameters by a novel biosensor-based approach.	PDGFRB PIK3R1	1.85e-05	3	87	2	8388538
Pubmed	Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.	CACNA1C CACNA1S	1.85e-05	3	87	2	17289261
Pubmed	Regulation of anterograde transport of adrenergic and angiotensin II receptors by Rab2 and Rab6 GTPases.	ADRB2 RAB2A	1.85e-05	3	87	2	17716866
Pubmed	Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.	KMT2A AFDN	1.85e-05	3	87	2	23361907
Pubmed	The covalent modification and regulation of TLR8 in HEK-293 cells stimulated with imidazoquinoline agonists.	PIK3R1 DHX9	1.85e-05	3	87	2	17868034
Pubmed	N-cadherin signaling via Trio assembles adherens junctions to restrict endothelial permeability.	TRIO PDGFRB	1.85e-05	3	87	2	30463880
Pubmed	The N-ethylmaleimide-sensitive fusion protein (NSF) is preferentially expressed in the nervous system.	NAPB NAPA	1.85e-05	3	87	2	8013662
Pubmed	TRPV6, TRPM6 and TRPM7 Do Not Contribute to Hair-Cell Mechanotransduction.	TRPM6 TRPM7	1.85e-05	3	87	2	29515374
Pubmed	GM1 inhibits early signaling events mediated by PDGF receptor in cultured human glioma cells.	PDGFRB PIK3R1	1.85e-05	3	87	2	10697503
Pubmed	The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.	KMT2A AFDN	1.85e-05	3	87	2	16239140
Pubmed	Phosphorylation of Ser1928 mediates the enhanced activity of the L-type Ca2+ channel Cav1.2 by the β2-adrenergic receptor in neurons.	CACNA1C ADRB2	1.85e-05	3	87	2	28119465
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	PDGFRB PIK3R1 SYNE2 AIPL1 CCND1 EPG5	2.72e-05	233	87	6	32290105
Pubmed	International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.	TRPM6 TRPM7 MCOLN3	3.34e-05	25	87	3	16382100
Pubmed	Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.	CACNA1C CACNA1S	3.70e-05	4	87	2	20937870
Pubmed	Binding to the platelet-derived growth factor receptor transiently activates the p85alpha-p110alpha phosphoinositide 3-kinase complex in vivo.	PDGFRB PIK3R1	3.70e-05	4	87	2	8702949
Pubmed	Alternative modes of binding of proteins with tandem SH2 domains.	PDGFRB PIK3R1	3.70e-05	4	87	2	10752619
Pubmed	Human brain-specific L-proline transporter: molecular cloning, functional expression, and chromosomal localization of the gene in human and mouse genomes.	ADRB2 PDGFRB	3.70e-05	4	87	2	7651355
Pubmed	Differential roles of proteasome and immunoproteasome regulators Pa28αβ, Pa28γ and Pa200 in the degradation of oxidized proteins.	PSME4 PSME3	3.70e-05	4	87	2	22564544
Pubmed	Structural determinants of the Na+/H+ exchanger regulatory factor interaction with the beta 2 adrenergic and platelet-derived growth factor receptors.	ADRB2 PDGFRB	3.70e-05	4	87	2	11882663
Pubmed	The kinase domain and membrane localization determine intracellular interactions between epidermal growth factor receptors.	PDGFRB PIK3R1	3.70e-05	4	87	2	7531698
Pubmed	SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors.	PDGFRB PIK3R1	3.70e-05	4	87	2	1372092
Pubmed	Physical and functional interactions between SH2 and SH3 domains of the Src family protein tyrosine kinase p59fyn.	PDGFRB PIK3R1	3.70e-05	4	87	2	7520528
Pubmed	Commensal bacteria direct selective cargo sorting to promote symbiosis.	LRRK2 RAB2A	3.70e-05	4	87	2	26237551
Pubmed	Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain.	TRIO MCF2	3.70e-05	4	87	2	17606614
Pubmed	An introduction to TRP channels.	TRPM6 TRPM7 MCOLN3	4.23e-05	27	87	3	16460286
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	TRPM6 DNAH10 TRIO PDGFRB PDS5A AFDN CLASP2 PSME3 COASY PEAK1 RAB2A DNAH5 DHX9	5.29e-05	1425	87	13	30948266
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RALGAPA1 TRIO TRPM7 ELMO2 SYNE2 KMT2A AFDN CLASP2 STK32C PEAK1	5.88e-05	861	87	10	36931259
Pubmed	A multisubunit particle implicated in membrane fusion.	NAPB NAPA	6.16e-05	5	87	2	1315316
Pubmed	Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively.	PDGFRB PIK3R1	6.16e-05	5	87	2	7678051
Pubmed	Evaluation of Lineage/Site-specific Nuclear Immunohistochemical Markers SATB2, Cyclin D1, SALL4, and BCOR in High-grade Endometrial Carcinomas.	CCND1 BCOR	6.16e-05	5	87	2	36731037
Pubmed	FAK integrates growth-factor and integrin signals to promote cell migration.	PDGFRB PIK3R1	6.16e-05	5	87	2	10806474
Cytoband	5p15.2	TRIO DNAH5	1.21e-03	27	87	2	5p15.2
Cytoband	2q11.1	TRIM43B TRIM43	1.30e-03	28	87	2	2q11.1
Cytoband	5p13.2	RANBP3L CPLANE1	1.59e-03	31	87	2	5p13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr5p13	RANBP3L MROH2B CPLANE1	2.39e-03	139	87	3	chr5p13
GeneFamily	Transient receptor potential cation channels	TRPM6 TRPM7 MCOLN3	1.13e-04	28	61	3	249
GeneFamily	Zinc fingers CXXC-type	KMT2A FBXL19	7.23e-04	12	61	2	136
GeneFamily	ATP binding cassette subfamily A	ABCA13 ABCA9	9.93e-04	14	61	2	805
GeneFamily	Potassium two pore domain channel subfamily K	KCNK13 KCNK12	1.14e-03	15	61	2	277
GeneFamily	Dyneins, axonemal	DNAH10 DNAH5	1.47e-03	17	61	2	536
GeneFamily	Calcium voltage-gated channel subunits	CACNA1C CACNA1S	3.45e-03	26	61	2	253
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	CACNA1C PDE1A NBEAL1 LAMA3 CLASP2 INPP4B SLC35F4	8.76e-08	188	87	7	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	ASK454-Immune-T_cell\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	NBEAL1 EML4 PIK3R1 SYNE2 ZNF75A ABCD2 INPP4B	1.05e-07	193	87	7	27c38a364bcdb4c0967155f18aa81d37e17c920b
ToppCell	ASK454-Immune-T_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	NBEAL1 EML4 PIK3R1 SYNE2 ZNF75A ABCD2 INPP4B	1.05e-07	193	87	7	11e1db416dc9a0b99ddb72d6021fba6e25405b5c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDE1A ABCA13 SYNE2 LRRK2 LAMA3 AFDN DNAH5	1.09e-07	194	87	7	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EML4 PIK3R1 ERICH6B SYNE2 INPP4B DHX9	7.88e-07	162	87	6	80317c4253bf8e897782e562f29835f181c65b98
ToppCell	LV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	CACNA1C RANBP3L PDGFRB IL1RAPL2 NBEAL1 LAMA3	8.77e-07	165	87	6	f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	CACNA1C PDE1A RANBP3L PDGFRB NBEAL1 LAMA3	1.08e-06	171	87	6	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	CACNA1C PDGFRB NBEAL1 LAMA3 INPP4B SLC35F4	1.60e-06	183	87	6	818fd886e0188091310825f9145fa53328f2c979
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RALGAPA1 TRPM7 EML4 SYNE2 KMT2A EPG5	1.87e-06	188	87	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RALGAPA1 EML4 SYNE2 KMT2A CLASP2 INPP4B	2.12e-06	192	87	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIG4 EML4 ASPM PDS5A DHX9 DNTT	2.25e-06	194	87	6	8ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCell	healthy_donor-Lymphocytic-T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	EML4 PIK3R1 SYNE2 KMT2A ABCD2 INPP4B	2.46e-06	197	87	6	63d0f06e150e7eb800ecb70e97b9d12a01c84e37
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	FAM156A PDGFRB SYNE2 MCF2 ENPP5 STRIP2	2.53e-06	198	87	6	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	EML4 PIK3R1 SYNE2 PHTF2 KMT2A INPP4B	2.60e-06	199	87	6	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	RALGAPA1 PSME4 EML4 SYNE2 INPP4B	1.38e-05	156	87	5	1545169694f686d28648a68b552c2ae606599d66
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 TRPM7 IL1RAPL2 MED12L ABCA9	1.56e-05	160	87	5	8bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 TRPM7 IL1RAPL2 MED12L ABCA9	1.56e-05	160	87	5	2d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	RALGAPA1 EML4 SYNE2 ABCD2 INPP4B	1.66e-05	162	87	5	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WDR91 ABCA13 SYNE2 LRRK2 DNAH5	1.76e-05	164	87	5	1cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EML4 PIK3R1 SYNE2 INPP4B MAP3K4	1.92e-05	167	87	5	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	droplet-Lung-nan-18m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S LRRK2 CCND1 KCNK12 STRIP2	2.03e-05	169	87	5	149a4f83da15bdeb170e980fb5b5b1af89ae07a6
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRPM6 ABCA13 ASPM MED12L HS3ST5	2.09e-05	170	87	5	cf22a843ae2d9cd6693507fed2b7c6a45abea10e
ToppCell	normal-na-Lymphocytic_T-T4_em-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	EML4 PIK3R1 SYNE2 AFDN INPP4B	2.15e-05	171	87	5	61318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell	COVID-19-kidney-REN+Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDE1A PDGFRB NBEAL1 PHTF2 INPP4B	2.34e-05	174	87	5	8393f0b43c767839c1630bcb952d62b42efc788d
ToppCell	COVID-19-kidney-REN+Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1C PDE1A PDGFRB PHTF2 INPP4B	2.67e-05	179	87	5	342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1A RANBP3L ABCA13 PIK3R1 CCND1	2.75e-05	180	87	5	0b653b1b653b40f3b8711d1312029a4a8a4961db
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB PHTF2 MCF2 PEAK1 MCOLN3	2.82e-05	181	87	5	a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB PHTF2 MCF2 PEAK1 MCOLN3	2.82e-05	181	87	5	526e858a848470b6d2d5248788004d9735ed3add
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE1A PDGFRB MROH2B ABCA9 MCOLN3	2.90e-05	182	87	5	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1A NALCN RANBP3L ABCA13 CCND1	2.97e-05	183	87	5	03c7e69136d5a3b9c5b2c91733e9b1c791f45c49
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	CACNA1C PDGFRB NBEAL1 LAMA3 SLC35F4	2.97e-05	183	87	5	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	Healthy/Control-CD4+_CTL\|Healthy/Control / Disease group and Cell class	TRAV12-2 ADRB2 EML4 PIK3R1 SYNE2	3.05e-05	184	87	5	6c6ffa150f81e456f88e9065de90c2dcda417589
ToppCell	LA-07._Pericyte\|LA / Chamber and Cluster_Paper	CACNA1C PDE1A PDGFRB NBEAL1 INPP4B	3.13e-05	185	87	5	ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCell	Healthy/Control-CD4+_CTL\|World / Disease group and Cell class	TRAV12-2 ADRB2 EML4 PIK3R1 SYNE2	3.30e-05	187	87	5	d54d3214d77a9469e94a16c00a80626fd4953e2b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	EML4 PIK3R1 SYNE2 INPP4B MAP3K4	3.30e-05	187	87	5	e1d6c1194476cf26969e405b0951796fed519f44
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 RANBP3L TRPM7 IL1RAPL2 MED12L	3.38e-05	188	87	5	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	ILEUM-inflamed-(1)_Cytotoxic_CD8_Trm\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RALGAPA1 ADRB2 EML4 PIK3R1 SYNE2	3.38e-05	188	87	5	d26894d1066a70e4b32ae41fff1c4718f2591ba9
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSME4 NBEAL1 EML4 SYNE2 PDS5A	3.65e-05	191	87	5	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRIO ABCA13 SYNE2 LRRK2 DNAH5	3.65e-05	191	87	5	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	NBEAL1 TMEM245 LRRK2 LAMA3 AFDN	3.65e-05	191	87	5	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSME4 NBEAL1 EML4 SYNE2 PDS5A	3.65e-05	191	87	5	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSME4 NBEAL1 EML4 SYNE2 PDS5A	3.65e-05	191	87	5	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	RALGAPA1 NBEAL1 PDS5A BCOR CPLANE1	3.83e-05	193	87	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDE1A SYNE2 LAMA3 AFDN DNAH5	3.83e-05	193	87	5	f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	CACNA1C RANBP3L PDGFRB ABCA9 MCOLN3	3.83e-05	193	87	5	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH10 ABCA13 ASPM MED12L HS3ST5	3.83e-05	193	87	5	ccab6a0c76f574ef7e1d6d5f1e620376daf21bbf
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	CACNA1C NALCN RANBP3L MCOLN3 INPP4B	3.83e-05	193	87	5	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDE1A SYNE2 LAMA3 AFDN DNAH5	3.83e-05	193	87	5	42df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	CACNA1C PDE1A NALCN PDGFRB ABCA9	3.93e-05	194	87	5	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DNAH10 ABCA13 ASPM MED12L HS3ST5	3.93e-05	194	87	5	23318a1b55895b5166c6151f488a94a09b4627ff
ToppCell	Control-Lymphoid-CD4_T_cells\|Lymphoid / Condition, Lineage and Cell class	TRAV12-2 SYNE2 PHTF2 INPP4B DHX9	4.02e-05	195	87	5	8679a122fe796b1eddef82460e985b3fd3b3a2a5
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	CACNA1C RANBP3L PDGFRB ABCA9 INPP4B	4.02e-05	195	87	5	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 TRPM7 PIK3R1 MED12L ABCA9	4.02e-05	195	87	5	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-T4_em-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NBEAL1 EML4 PIK3R1 SYNE2 INPP4B	4.02e-05	195	87	5	48905d57775ec90cc031af0863cc8c3800f2e48e
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-T4_reg-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NBEAL1 EML4 PIK3R1 SYNE2 INPP4B	4.02e-05	195	87	5	911a37684c1f93d537f51ee71cb1ccec06840315
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	EML4 SYNE2 KMT2A INPP4B MAP3K4	4.22e-05	197	87	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE1A SYNE2 HS3ST5 DNAH5 INPP4B	4.33e-05	198	87	5	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C PDE1A PDGFRB LAMA3 INPP4B	4.33e-05	198	87	5	b7e900fc0a1b3fa5e47dcc36ce6b0c3ce6bf9739
ToppCell	COVID-19_Moderate-CD4+_CTL\|World / disease group, cell group and cell class	ADRB2 EML4 PIK3R1 SYNE2 AFDN	4.43e-05	199	87	5	12ea0346b4da3e8e2b3b2b3b3e9d4f4f104345a6
ToppCell	Bronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C PDGFRB ASPM LAMA3 INPP4B	4.43e-05	199	87	5	78a9b26215874a46a910a4b93a51fcac1a597618
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TRIO SYNE2 KMT2A AFDN FAM13B	4.54e-05	200	87	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	COVID-19_Moderate-CD4+_CTL\|COVID-19_Moderate / disease group, cell group and cell class	ADRB2 EML4 PIK3R1 SYNE2 AFDN	4.54e-05	200	87	5	a9c73559e2c9fda1b065bfb5ce84978995505924
ToppCell	severe-MAIT\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ADRB2 EML4 PIK3R1 SYNE2 KMT2A	4.54e-05	200	87	5	8a849d0ef244aa2666da2d31bd0731fb04e40911
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 ASPM LAMA3 UNC13A	1.06e-04	125	87	4	35042ed43045dddc341b76cc5f9fe31b5ba0abb8
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast-MyoFB-1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	DNAH10 ERICH6B DNAH5 UNC13A	1.87e-04	145	87	4	ac41c6c02b7d78162b86222983688f54d04ac47d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CACNA1C PDE1A SYNE2 INPP4B	1.97e-04	147	87	4	5e6dd2ddc67b3722f6528e7277cbc7f296098687
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBXO40 PDGFRB PHTF2 MCF2	2.13e-04	150	87	4	8645b9c7f9511ed6cc9afe04440c2873a3094150
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	SYNE2 KMT2A ABCD2 INPP4B	2.19e-04	151	87	4	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	Bac-SEP-Lymphocyte-T_NK-CD4_TEM\|Bac-SEP / Disease, Lineage and Cell Type	TRPM6 EML4 PIK3R1 SYNE2	2.47e-04	156	87	4	ef6bad99bcb30956863cd490c613e251f3b27ba0
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	DNAH10 ABCA13 SYNE2 INPP4B	2.47e-04	156	87	4	10d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C RANBP3L MROH2B ABCA9	2.60e-04	158	87	4	e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRPM6 PDE1A VASH2 CCND1	2.66e-04	159	87	4	22427ad4ad2e797e4664e7a7b0514094f22a18b2
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D122\|Adult / Lineage, Cell type, age group and donor	CACNA1C PDGFRB INPP4B SLC35F4	2.73e-04	160	87	4	fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	CACNA1C RANBP3L PDGFRB LAMA3	2.73e-04	160	87	4	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	Globus_pallidus-Neuronal-Excitatory\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	LRRK2 STK32C STRIP2 SLC35F4	2.73e-04	160	87	4	f843287ed57d2d5a3b3f6dfb03b6934e330e6645
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	CACNA1C RANBP3L PDGFRB LAMA3	2.79e-04	161	87	4	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C PDGFRB ASPM INPP4B	2.92e-04	163	87	4	51dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCell	Basal_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	TRPM6 PDE1A ABCA13 ABCD2	2.92e-04	163	87	4	679e25e5548d157d49a73057a3b5617dccda260f
ToppCell	facs-Spleen-nan-3m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELMO2 PIK3R1 STK32C PEAK1	2.99e-04	164	87	4	a187bd5beca017ef657ef07c006e7f94ea3b911b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB PHTF2 MCF2 MCOLN3	2.99e-04	164	87	4	b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PIK3R1 STK32C PEAK1 PTPN18	2.99e-04	164	87	4	c2cd4e4b88cc1b80a9494f59d31339007ff824c1
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADRB2 PIK3R1 TMEM245 ENPP5	2.99e-04	164	87	4	a5227971a71345854e0538e42da684de87febda0
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PIK3R1 STK32C PEAK1 PTPN18	2.99e-04	164	87	4	d4d08353c7322f97ea07dd583b08661d635fff20
ToppCell	droplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR91 CACNA1S MED12L STRIP2	2.99e-04	164	87	4	78de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ASPM MED12L PTPN18 ABCA9	3.06e-04	165	87	4	cece16b03282d27fb49102eb9c104a2024efd28c
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PIK3R1 STK32C PEAK1 PTPN18	3.06e-04	165	87	4	88745bf7ecb0f7fc93077cea20171d40535dd56b
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WDR91 CACNA1S MED12L STRIP2	3.06e-04	165	87	4	c39f0479955c4e23921f7a450d3bc251a002200f
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|356C / Donor, Lineage, Cell class and subclass (all cells)	SYNE2 INTS1 ENPP5 EPG5	3.13e-04	166	87	4	c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDGFRB ERICH6B SYNE2 ASPM	3.21e-04	167	87	4	abc4ba308ca3be41b0da604f5d82579fd58dff7b
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PIK3R1 FAM78B SYNE2 INPP4B	3.28e-04	168	87	4	5e721268f0baa51d3f640f7f4c41db769ebef210
ToppCell	droplet-Lung-LUNG-30m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM43B CACNA1S CCND1 STRIP2	3.28e-04	168	87	4	0e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRK2 PDS5A CCND1 CPLANE1	3.28e-04	168	87	4	d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRIM43B CACNA1S CCND1 STRIP2	3.35e-04	169	87	4	b2d53159e344fad6fcdc485d5b8f6cf1bf094b1f
ToppCell	facs-Marrow-T_cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCF2 TRIM43 STRIP2 DNTT	3.35e-04	169	87	4	2a35846b0e0be0a19a5a04a86cbd72ce65257c8a
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NALCN DNAH10 ABCA13 DNAH5	3.35e-04	169	87	4	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	COVID-19_Severe-Treg\|COVID-19_Severe / disease group, cell group and cell class	EML4 PIK3R1 SYNE2 PPP1R2C	3.43e-04	170	87	4	d61269a51283125835884c4aa50623756c4fdda2
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1S CCND1 KCNK12 STRIP2	3.43e-04	170	87	4	bf589c4297ccc90e5f51e3d0fcc229548af4fcef
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTLL2 TMEM245 DNAH5 STRIP2	3.43e-04	170	87	4	17bd7fd25a2657cb536ad47e294332920f759e95
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB PHTF2 MCF2 MCOLN3	3.43e-04	170	87	4	876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB PHTF2 MCF2 MCOLN3	3.43e-04	170	87	4	1f8738acf439d893880db7e1fdc9b3615ca00c39
Disease	Multiple myeloma	LIG4 CCND1	7.82e-06	2	83	2	cv:C0026764
Disease	MYELOMA, MULTIPLE	LIG4 CCND1	7.82e-06	2	83	2	254500
Disease	Ovarian Serous Adenocarcinoma	TRPM7 LRRK2 MAP3K4	3.65e-05	23	83	3	C1335177
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1C CACNA1S	4.67e-05	4	83	2	DOID:0060173 (implicated_via_orthology)
Disease	lung small cell carcinoma (is_implicated_in)	PIK3R1 LAMA3 CCND1	6.68e-05	28	83	3	DOID:5409 (is_implicated_in)
Disease	response to bevacizumab, Proteinuria	TRIO DNAH5	7.77e-05	5	83	2	EFO_0005943, HP_0000093
Disease	thigh muscle volume	CACNA1S PIK3R1	1.16e-04	6	83	2	EFO_0020107
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1C CACNA1S EML4	1.43e-04	36	83	3	DOID:11723 (implicated_via_orthology)
Disease	RS-10-hydroxywarfarin measurement	TRPM6 LIG4 TAS2R9 NALCN	1.72e-04	98	83	4	EFO_0803330
Disease	chemotherapy-induced alopecia, methylcobalamin deficiency type cblE	TRIO DNAH5	2.16e-04	8	83	2	EFO_0005400, MONDO_0009354
Disease	leukemia	LIG4 KMT2A CCND1	5.07e-04	55	83	3	C0023418
Disease	non-Hodgkin lymphoma (is_implicated_in)	KMT2A CCND1	1.03e-03	17	83	2	DOID:0060060 (is_implicated_in)
Disease	Muscle hypotonia	RALGAPA1 INTS1	1.03e-03	17	83	2	C0026827
Disease	Antibody Deficiency Syndrome	CACNA1C EPG5	1.03e-03	17	83	2	C0003257
Disease	tissue plasminogen activator measurement, coronary artery disease	NBEAL1 TAP2 MAP3K4	1.07e-03	71	83	3	EFO_0001645, EFO_0004791
Disease	waist circumference	RALGAPA1 DNAH10 TRIO TRPM7 SYNE2 DNAH5	1.34e-03	429	83	6	EFO_0004342
Disease	selenium measurement, response to dietary selenium supplementation	TRIO DNAH5	1.44e-03	20	83	2	EFO_0006331, EFO_0600021
Disease	Leukemia, Myelocytic, Acute	TRIO KMT2A BCOR INPP4B	1.46e-03	173	83	4	C0023467
Disease	Infiltrating duct carcinoma of female breast	TRPM7 PDGFRB	1.59e-03	21	83	2	C3165106
Disease	Bronchiectasis	PIK3R1 DNAH5	1.74e-03	22	83	2	C0006267
Disease	Immunologic Deficiency Syndromes	CACNA1C EPG5	1.90e-03	23	83	2	C0021051
Disease	response to radiation	AIPL1 DNAH5 EPG5	1.98e-03	88	83	3	GO_0009314
Disease	body fat percentage, high density lipoprotein cholesterol measurement	DNAH10 PIK3R1	2.25e-03	25	83	2	EFO_0004612, EFO_0007800
Disease	putamen volume change measurement, age at assessment	TMEM245 DNTT	2.62e-03	27	83	2	EFO_0008007, EFO_0021495

Protein segments in the cluster

Peptide	Gene	Start	Entry
LIKEKWLNEDIMLRT	PTPN18	161	Q99952
LKRVLKELWKLVMNT	UNC13A	1371	Q9UPW8
RLRKLMLEWQFQKRL	AFDN	1556	P55196
ESENRWKLVIMLKKN	ERICH6B	386	Q5W0A0
NEMKVLLILSKWLEQ	EPG5	2391	Q9HCE0
TKNKARVIILMVWIV	ADRB2	146	P07550
ERQLKKLISLRDWML	AIG1	76	Q9NVV5
QWLKLEKMINTLILN	AIPL1	221	Q9NZN9
RTFIIKLIKWLMIAI	ABCD2	141	Q9UBJ2
LKKWRMKRQTLLEWL	ABCA9	21	Q8IUA7
KEKIILQTIKWRMRV	FAM78B	181	Q5VT40
KMVICLTLEALWKNL	ABCA13	2736	Q86UQ4
ELLQMELLLVNKLKW	CCND1	136	P24385
ELLLVNKLKWNLAAM	CCND1	141	P24385
RNWLLLSDVLKKLKM	BCOR	1661	Q6W2J9
WRRVLAQRKLLMLKK	ASPM	1326	Q8IZT6
SKKQLMWLLNRLQGL	FBXL19	496	Q6PCT2
KLTLLQKMLEWAISE	NBEAL1	1491	Q6ZS30
RMITIDGKQIKLQIW	RAB2A	46	P61019
VQAIKLLVRWLLGMK	PDS5A	836	Q29RF7
QESKIMFQRLLKQWL	FAM156A	196	Q8NDB6
SWLELQLMIKQCLKD	MED12L	1326	Q86YW9
SIQIKIGKLQKRMWI	LAMA3	2681	Q16787
KEVRLLAVQKLEMWL	INTS1	361	Q8N201
WKLAIQILKIAMVTI	MCOLN3	61	Q8TDD5
MVKLLVWQKSVHKLR	FAM182A	111	Q5T1J6
KKRKNVEIMWLAATI	INPP4B	816	O15327
NEELNIKLARQLMWK	PPP1R2C	146	O14990
IKLARQLMWKELQSE	PPP1R2C	151	O14990
VLKWMTELTKLRKQI	FAM13B	606	Q9NYF5
MLFKQQAWLRQKLLV	HS3ST5	1	Q8IZT8
LIKQVLNWMLRKLSC	KCNK12	301	Q9HB15
MKNLWCEKLSIVRKR	OR4A16	296	Q8NH70
KMWQRLKGILRCLVK	PDE1A	26	P54750
LQNWLDIKRTLLMIK	PEAK1	1691	Q9H792
MLKKAKLWNTLNLII	ENPP5	221	Q9UJA9
KWLCKIMAQILTVKV	LRRK2	1601	Q5S007
ILIKQSLNWILRKMD	KCNK13	281	Q9HB14
LMWLTQKGVRQKKLN	PIK3R1	581	P27986
FQLPMKKIVWLKLLI	GSTT4	106	A0A1W2PR19
IIKKIWKRTSMKLLD	CACNA1C	1636	Q13936
LEQKWLIRMIIKDLK	LIG4	181	P49917
YILQLRWARKVMQKI	CPLANE1	1211	Q9H799
ICIQLLNKTWKEMRA	ELMO2	451	Q96JJ3
KIWKRTSMKLLDQVI	CACNA1S	1496	Q13698
LQERGMVLLQWKKKR	FBXO40	611	Q9UH90
VKMTWLKEIRNILLK	MCF2	796	P10911
LMLWLQQEQKRKESI	KMT2A	3646	Q03164
DMSIIQWKLVEKLSL	EML4	856	Q9HC35
RILINLMKYLQKWKR	DNAH10	981	Q8IVF4
MRLSQLKQLLKKEWL	CCDC124	191	Q96CT7
RMTWEAKVQLKEILI	DHX9	951	Q08211
LLLNDWRKEMKARKI	DNAH5	3541	Q8TE73
IISLIILIMLWQKKP	PDGFRB	546	P09619
WLNITKDLNQKLRIM	MAP3K4	396	Q9Y6R4
VQLAKAVLRMLLLLW	PEX16	116	Q9Y5Y5
LFQRKLSWIKMTKLE	FAN1	421	Q9Y2M0
RLKKVQNIKMWLSLR	PHTF2	606	Q8N3S3
HREKLLKQMRILWKK	TRIM43	136	Q96BQ3
LKQMRILWKKIQENQ	TRIM43	141	Q96BQ3
IKKVLLLLWKVVMFT	STRIP2	266	Q9ULQ0
KRWRKLVSKTQLEMN	SYNE2	656	Q8WXH0
LQKVMNLWEKKGLLL	DNTT	361	P04053
KMWRSIIIQKGNALL	IL1RAPL2	186	Q9NP60
LEFLLNKLMKLWKID	PPP1R42	186	Q7Z4L9
QVNNKVLMWRLLKLS	TAP2	131	Q03519
RLDQWLTTMLLRIKK	NAPA	271	P54920
ETMLLQLLKESLWKI	MROH2B	571	Q7Z745
ILVKMRKEDKSLVWL	SLC35F4	41	A4IF30
WSKEMVALLRKLLTV	STK32C	321	Q86UX6
QLKILTDIMWPIIAK	COASY	436	Q13057
QDWLFVLLTQLLKKM	CLASP2	731	O75122
IRLLIEKCNTVKMWV	PSME3	126	P61289
RLKMRKNSWLKIIIS	TRPM6	736	Q9BX84
KKTWEQMLLVLLRVT	RALGAPA1	576	Q6GYQ0
WLKLKINKVMLAILL	TAS2R9	121	Q9NYW1
LILNSKLWAQMKIQR	RANBP3L	351	Q86VV4
MKSLRVLLVILWLQL	TRAV12-2	1	A0A075B6T6
PIEWKQLVLNVSKML	VASH2	261	Q86V25
LWKKIHRMVILTILA	TTLL2	341	Q9BWV7
RLDQWLTTMLLRIKK	NAPB	271	Q9H115
NGRWLNKLMKLLQRL	PSME4	346	Q14997
IKLLKTILKWLMASA	PSME4	1571	Q14997
IWLEKMLDKIISIFI	TMEM245	451	Q9H330
LKQMRILWKKIQENQ	TRIM43B	141	A6NCK2
KLSTWKQELLKLMDR	ZNF75A	136	Q96N20
RLLLWDTKTMKQQLQ	WDR91	541	A4D1P6
MRLWKARVLKLVLKT	ATP6AP1L	1	Q52LC2
LQLLLKEWQMELPKL	TRPM7	121	Q96QT4
WQQLMLKMEDRLKLV	TRIO	996	O75962
EVAKQTIRMWLKKCL	NALCN	1566	Q8IZF0