Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentprotein kinase CK2 complex

CSNK2A3 CSNK2A1

2.14e-054402GO:0005956
DomainDEP

DVL3 DEPDC5

1.06e-0322412PF00610
DomainRHOD

TST TBCK

1.06e-0322412SM00450
DomainDEP

DVL3 DEPDC5

1.06e-0322412SM00049
DomainDEP

DVL3 DEPDC5

1.06e-0322412PS50186
DomainDEP_dom

DVL3 DEPDC5

1.16e-0323412IPR000591
DomainRHODANESE_3

TST TBCK

1.16e-0323412PS50206
DomainRhodanese-like_dom

TST TBCK

1.26e-0324412IPR001763
Domain-

TST TBCK

1.26e-03244123.40.250.10
DomainRhodanese

TST TBCK

1.26e-0324412PF00581
DomainDnaJ_domain_CS

DNAJB8 DNAJA4

1.59e-0327412IPR018253
DomainProt_kinase_dom

AATK CSNK2A3 CSNK2A1 NTRK1 TBCK

4.15e-03489415IPR000719
DomainPROTEIN_KINASE_DOM

AATK CSNK2A3 CSNK2A1 NTRK1 TBCK

4.30e-03493415PS50011
Domainzf-C4

NR3C2 PPARA

4.58e-0346412PF00105
DomainNUCLEAR_REC_DBD_1

NR3C2 PPARA

4.58e-0346412PS00031
DomainZnf_hrmn_rcpt

NR3C2 PPARA

4.58e-0346412IPR001628
DomainZnF_C4

NR3C2 PPARA

4.58e-0346412SM00399
DomainNUCLEAR_REC_DBD_2

NR3C2 PPARA

4.58e-0346412PS51030
Domain-

NR3C2 PPARA

4.77e-03474121.10.565.10
DomainHOLI

NR3C2 PPARA

4.98e-0348412SM00430
DomainDnaJ

DNAJB8 DNAJA4

4.98e-0348412PF00226
DomainNucl_hrmn_rcpt_lig-bd

NR3C2 PPARA

4.98e-0348412IPR000536
DomainHormone_recep

NR3C2 PPARA

4.98e-0348412PF00104
DomainDnaJ

DNAJB8 DNAJA4

5.18e-0349412SM00271
DomainDNAJ_1

DNAJB8 DNAJA4

5.18e-0349412PS00636
DomainDNAJ_2

DNAJB8 DNAJA4

5.18e-0349412PS50076
Domain-

DNAJB8 DNAJA4

5.18e-03494121.10.287.110
DomainDnaJ_domain

DNAJB8 DNAJA4

5.60e-0351412IPR001623
DomainKinase-like_dom

AATK CSNK2A3 CSNK2A1 NTRK1 TBCK

6.39e-03542415IPR011009
Domain-

NR3C2 PPARA

6.95e-03574123.30.50.10
DomainZnf_NHR/GATA

NR3C2 PPARA

7.19e-0358412IPR013088
Pubmed

Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2.

CSNK2A3 CSNK2A1

1.36e-06241214646071
Pubmed

Assignment of casein kinase 2 alpha sequences to two different human chromosomes.

CSNK2A3 CSNK2A1

1.36e-0624121577469
Pubmed

Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway.

DEPDC5 PPARA

1.36e-06241234267188
Pubmed

Repurposing Riociguat to Target a Novel Paracrine Nitric Oxide-TRPC6 Pathway to Prevent Podocyte Injury.

GUCY1A1 TRPC6

1.36e-06241234830371
Pubmed

Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.

CSNK2A3 CSNK2A1

1.36e-06241212860116
Pubmed

Molecular cloning of the human casein kinase II alpha subunit.

CSNK2A3 CSNK2A1

1.36e-0624122752008
Pubmed

Structure and sequence of an intronless gene for human casein kinase II-alpha subunit.

CSNK2A3 CSNK2A1

1.36e-0624128420794
Pubmed

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation.

CSNK2A3 CSNK2A1

4.06e-06341215684395
Pubmed

Isolation and characterization of human cDNA clones encoding the alpha and the alpha' subunits of casein kinase II.

CSNK2A3 CSNK2A1

4.06e-0634122174700
Pubmed

Mapping of the human casein kinase II catalytic subunit genes: two loci carrying the homologous sequences for the alpha subunit.

CSNK2A3 CSNK2A1

4.06e-0634121766873
Pubmed

Crystallization and preliminary characterization of crystals of human protein kinase CK2.

CSNK2A3 CSNK2A1

4.06e-06341211092945
Pubmed

Sequencing of full-length cDNA encoding the alpha and beta subunits of human casein kinase II from human platelets and megakaryocytic cells. Expression of the casein kinase IIalpha intronless gene in a megakaryocytic cell line.

CSNK2A3 CSNK2A1

4.06e-06341212102635
Pubmed

SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα.

NCOA2 PPARA

4.06e-06341231851938
Pubmed

Functional polymorphism of the CK2alpha intronless gene plays oncogenic roles in lung cancer.

CSNK2A3 CSNK2A1

4.06e-06341220625391
Pubmed

cDNA cloning, expression pattern, and chromosomal localization of Mlf1, murine homologue of a gene involved in myelodysplasia and acute myeloid leukemia.

MLF1 NTRK1

8.12e-06441210393836
Pubmed

Gene fusions AHRR-NCOA2, NCOA2-ETV4, ETV4-AHRR, P4HA2-TBCK, and TBCK-P4HA2 resulting from the translocations t(5;8;17)(p15;q13;q21) and t(4;5)(q24;q31) in a soft tissue angiofibroma.

NCOA2 TBCK

1.35e-05541227633981
Pubmed

SIP, a novel ankyrin repeat containing protein, sequesters steroid receptor coactivators in the cytoplasm.

NCOA2 CSNK2A1

1.35e-05541217476305
Pubmed

COP9 subunits 4 and 5 target soluble guanylyl cyclase α1 and p53 in prostate cancer cells.

GUCY1A1 CSNK2A1

1.35e-05541224725084
Pubmed

An Ankyrin-G N-terminal Gate and Protein Kinase CK2 Dually Regulate Binding of Voltage-gated Sodium and KCNQ2/3 Potassium Channels.

ANK3 CSNK2A1

1.35e-05541225998125
Pubmed

Steroid receptor coactivator-2 is a dual regulator of cardiac transcription factor function.

NCOA2 PPARA

2.03e-05641224811170
Pubmed

SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling.

DVL3 CSNK2A1

2.03e-05641220439735
Pubmed

Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells.

DVL3 CSNK2A1

2.84e-05741210806215
Pubmed

A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1.

CSNK2A3 CSNK2A1

2.84e-05741211239457
Pubmed

p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex.

CSNK2A3 CSNK2A1

3.78e-05841212393879
Pubmed

Structural determinants of the agonist-independent association of human peroxisome proliferator-activated receptors with coactivators.

NCOA2 PPARA

4.86e-05941215888456
Pubmed

USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification.

NPC1 DVL3 CSNK2A1

5.48e-056241331340145
Pubmed

Transcriptional cofactors exhibit differential preference toward peroxisome proliferator-activated receptors alpha and delta in uterine cells.

NCOA2 PPARA

6.07e-051041215001550
Pubmed

Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.

NCOA2 PPARA

1.05e-041341219255064
Pubmed

Evolutionary trajectory of receptor binding specificity and promiscuity of the spike protein of SARS-CoV-2.

CYC1 F8

1.41e-041541236305765
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

VIPR1 NR3C2 NTRK1

2.34e-0410141323382219
Pubmed

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity.

ANK3 NTRK1

2.54e-042041224776795
Pubmed

Tbx15 controls skeletal muscle fibre-type determination and muscle metabolism.

CYC1 PPARA

2.54e-042041226299309
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

NPC1 DEPDC5 PPARA AATK SBF1 VWA8 NLRX1

2.80e-04110541735748872
Pubmed

Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature.

DNAJB8 DNAJA4

3.09e-042241211147971
Pubmed

The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord.

GUCY1A1 NTRK1

3.38e-042341217954614
Pubmed

The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities.

DNAJB8 DNAJA4

3.38e-042341221231916
Pubmed

A microarray minisequencing system for pharmacogenetic profiling of antihypertensive drug response.

NR3C2 PPARA

4.00e-042541212544508
Pubmed

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

CYC1 PLA2G4A ATP5PF TST VWA8

4.26e-0454241514651853
Pubmed

The DNA sequence of human chromosome 22.

DEPDC5 PPARA TST SBF1

4.27e-0430041410591208
Pubmed

NPC1 is required for postnatal islet β cell differentiation by maintaining mitochondria turnover.

NPC1 ATP5PF

4.67e-042741238505613
Pubmed

Integrating genetic and network analysis to characterize genes related to mouse weight.

GUCY1A1 VWA8

5.39e-042941216934000
Pubmed

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

SBF1 RAB27B

8.80e-043741220937701
Pubmed

Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.

DEPDC5 ANK3

9.77e-043941222802532
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

DVL3 CYC1 SBF1 VWA8

1.01e-0337841434315543
Pubmed

Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.

DVL3 ANK3 SBF1

1.01e-0316741325659891
Pubmed

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes.

CYC1 ATP5PF VWA8 NLRX1

1.05e-0338241429222160
Pubmed

Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.

NPC1 PPARA

1.08e-034141219878569
Pubmed

Proteomic analysis of the mouse liver mitochondrial inner membrane.

CYC1 ATP5PF TST

1.16e-0317541312865426
InteractionCT45A3 interactions

DVL3 CSNK2A3 CSNK2A1

6.03e-079403int:CT45A3
InteractionTNP1 interactions

DVL3 PPARA CSNK2A1

1.57e-0612403int:TNP1
GeneFamilyReceptor Tyrosine Kinases|CD molecules

AATK NTRK1

1.50e-0340262321
GeneFamilyNuclear hormone receptors

NR3C2 PPARA

2.24e-034926271
GeneFamilyDNAJ (HSP40) heat shock proteins|C2 tensin-type domain containing

DNAJB8 DNAJA4

2.24e-0349262584
CoexpressionGSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN

NPC1 DVL3 NCOA2 NME8 NLRX1

1.37e-05197415M4421
CoexpressionGSE22886_NAIVE_TCELL_VS_NKCELL_DN

NPC1 DVL3 NCOA2 NME8 NLRX1

1.41e-05198415M4415
CoexpressionGSE32901_NAIVE_VS_TH1_CD4_TCELL_UP

VIPR1 SPO11 TST CCNB3

5.23e-05131414M8933
CoexpressionLAKE_ADULT_KIDNEY_C13_THICK_ASCENDING_LIMB

NCOA2 NR3C2 VWA8 TBCK

5.23e-05131414M39232
CoexpressionAtlasStem Cells, SC.LTSL.BM, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-2

PLA2G4A GUCY1A1 NYNRIN TRPC6

2.05e-0586404GSM399442_100
CoexpressionAtlasFetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3

PLA2G4A GUCY1A1 NYNRIN TRPC6

2.68e-0592404GSM791126_100
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Esm1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

VAT1L RAB27B NTRK1 TRPC6

6.39e-061314143cb4b272e28ee9bad6d874f64a7aae18352a6cfb
ToppCellsevere-unassigned|World / disease stage, cell group and cell class

DVL3 NCOA2 TST NME8

1.55e-05164414b3a45c150df6594debeeca400cc58d30ef662756
ToppCellsevere-unassigned|severe / disease stage, cell group and cell class

DVL3 NCOA2 TST NME8

1.59e-05165414f9ddd547992fec065d539a1d0305acba8fc7d79c
ToppCellPND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLA2G4A SPO11 RAB27B TRPC6

1.87e-05172414e39ea2f4edbf36ebf9604fa6f9349081859c596c
ToppCellPND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLA2G4A SPO11 RAB27B TRPC6

1.87e-05172414bcc50bed47465daa953ba91f17d1ee4c947ab461
ToppCellPND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLA2G4A SPO11 RAB27B TRPC6

1.87e-05172414875ea290840e835952623b905eb610f3c71456d2
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT2|E18.5-samps / Age Group, Lineage, Cell class and subclass

NPC1 TST ANK3 RAB27B

1.91e-05173414f6e36ea98a9c669ff393d141455aaecef083f738
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1|TCGA-Adrenal / Sample_Type by Project: Shred V9

CELF4 DNAJA4 RAB27B NTRK1

2.19e-05179414431e1b29015ec817f778499106d24b19cfc825ae
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR1 AATK GUCY1A1 TRPC6

2.24e-0518041478fdcfb3fdbf36469cae78407cda5bd0996930d8
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NPC1 TST ANK3 RAB27B

2.49e-05185414fd51fef8c69e34c72017d8371ab0a0d7be5701f2
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NPC1 TST ANK3 RAB27B

2.49e-05185414bea26e369ae91006052b973cd89b4c49afa9e553
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AATK TST GUCY1A1 RAB27B

2.59e-05187414644d49bf66745d2e2d0f9bb3290d3e60c4ca7c4a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Hematopoietic|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AATK TST GUCY1A1 RAB27B

2.59e-05187414ff84f75c10037f27c1f56eb1accd150cfe52f8e4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Hematopoietic-Megakaryocytic|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AATK TST GUCY1A1 RAB27B

2.59e-05187414854ef90afa59b18ee9f38cfb4659808b79c25202
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AATK TST GUCY1A1 RAB27B

2.59e-05187414eac261f16d3a9e9213199872dffccb9f4e1d6f18
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

NCOA2 NR3C2 VAT1L ANK3

2.71e-05189414830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ENPP6 VIPR1 RAB27B NYNRIN

2.76e-051904143cf464664d6aa22b212e60b70885953887e92483
ToppCellfacs-Marrow-KLS-18m-Hematologic-MPP_Fraction_A_+_HSC|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G4A GUCY1A1 RAB27B TRPC6

2.76e-0519041496a9756cad5468a12591021e6d661ed269b5b3d9
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF4 TST ANK3 RAB27B

2.82e-05191414b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

NPC1 NR3C2 ANK3 GUCY1A1

2.82e-05191414a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

NPC1 TST ANK3 RAB27B

2.82e-051914141cd4d513ac363fdda07030b85a88174d29af3588
ToppCellfacs-Marrow-KLS-3m-Hematologic-MPP_Fraction_A_+_HSC|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G4A GUCY1A1 RAB27B TRPC6

2.88e-05192414959c28d28397bc0b9d3970d1fe3293d2750e63d4
ToppCellHSPCs-Mk_prog.|HSPCs / Lineage and Cell class

PLA2G4A GUCY1A1 RAB27B TRPC6

3.00e-051944145c05d508f5c29e6efe87506bf59e3b0fe5922f65
ToppCellHSPCs-Mk_prog.|World / Lineage and Cell class

PLA2G4A GUCY1A1 RAB27B TRPC6

3.00e-051944145049f4f102844d766eca577e809cf21f7908a9d2
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLA2G4A VIPR1 DNAJA4 RAB27B

3.06e-05195414e87b11e3242fdbed2e7f383e6876ec375af32bd4
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

NCOA2 NR3C2 ANK3 VWA8

3.31e-0519941494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellPND01-03-samps-Mesenchymal-Pericyte-pericyte_E|PND01-03-samps / Age Group, Lineage, Cell class and subclass

AATK GUCY1A1 TRPC6

2.59e-0413541335928195cf34f055b353562c96f451aef2344d64
ToppCellLPS_only-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC25A48 NTRK1 NME8

2.65e-0413641382d7f90ef2a63a3137c331efd68c036cd0db3ac1
ToppCellCOVID-19_Convalescent-PLT_3|World / Disease Group and Platelet Clusters

NPC1 VWA8 NLRX1

2.71e-04137413bb54bb81b450462ad521b57e1a07a80ce1678e67
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CELF4 CCNB3 SLC25A48

2.76e-04138413611fe0fb284e12678f9c47a0bdbfc367a93c52b3
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC6A16 RAB27B TRPC6

2.94e-04141413ad9a25569c142fb68ded34aeba0cd9be8124ce56
ToppCellTCGA-Adrenal|World / Sample_Type by Project: Shred V9

CELF4 VAT1L NTRK1

3.19e-04145413522ad2bc90b8ec326fcbc7b2250b09566efeeca2
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_C|E18.5-samps / Age Group, Lineage, Cell class and subclass

NR3C2 GUCY1A1 TRPC6

3.60e-041514133f2abaa42876ce7a71d934ff16abe0cab0991a05
ToppCellLPS-IL1RA-Myeloid_granulocytic-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TST RAB27B NYNRIN

3.81e-0415441343735f7c58cac51855ded486ee8d8729a1b9909e
ToppCellLPS-IL1RA-Myeloid_granulocytic|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TST RAB27B NYNRIN

3.81e-04154413d55fb73461885e1e02061a344ff89624ef4de487
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GUCY1A1 SLC6A16 TRPC6

3.96e-041564130f2147abcf31a26ee5b2f4d8c5d72232612a33f0
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GUCY1A1 SLC6A16 TRPC6

3.96e-04156413cb87f12443fdc5538b856f765fcbac9406044e10
ToppCellCOVID_non-vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

GUCY1A1 NTRK1 NYNRIN

4.11e-041584130d4fe87fc7901dd5f9c004e91708a03cafdb4ad9
ToppCellNS-critical-d_16-33-Myeloid-Mast_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ENPP6 RAB27B NTRK1

4.26e-04160413c61869d9dbba250270e59366e15af204e5b4395d
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

NCOA2 ANK3 GUCY1A1

4.26e-041604138aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPARA GUCY1A1 TRPC6

4.34e-0416141382ed45f144a07856fe92d37426c5f92e259a03a9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Mast_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PLA2G4A RAB27B NTRK1

4.34e-04161413c54010d88f1ecb6e0235bb66084876a4d5bf1ecd
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NPC1 DNAJA4 RAB27B

4.50e-04163413d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCellSevere-Lymphoid-NK-CCR7+_T|Severe / Condition, Lineage, Cell class and cell subclass

VIPR1 ANK3 GUCY1A1

4.50e-041634138f0d8c124f1569a5a6bc1db7581989f24d63cca3
ToppCellClub_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

CELF4 VAT1L NYNRIN

4.58e-041644134e25e6362ef793b08de2f4d1dccb6b1fc9c072a5
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VAT1L AATK ANK3

4.58e-041644133caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCellmoderate-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CELF4 RAB27B NTRK1

4.74e-04166413c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCellP07-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TST ANK3 RAB27B

4.74e-04166413021b9344de7957762f81b09a647504b8c8289cf1
ToppCellfacs-Aorta-Heart-3m-Endothelial-endocardial_endothelial_cells|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 F8 RAB27B

4.83e-04167413a4a795751644b22af616335379e64ae95175180c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-4_VIP_CHRNA2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VAT1L SLC25A48 TRPC6

4.91e-0416841311ab08e373abe4bbd0f2134db38a2e8efa0eb159
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

VIPR1 CELF4 F8

5.00e-04169413987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCellP07-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TST ANK3 RAB27B

5.00e-0416941353e863de064d44e1d36e21fb3dbba37ae020f6e9
ToppCellP07-Epithelial-epithelial_progenitor_cell-epi_progenitor|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TST ANK3 RAB27B

5.00e-041694131a47a4892a5e6a69555f5332308503526e5422a7
ToppCellP07-Epithelial-epithelial_progenitor_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TST ANK3 RAB27B

5.00e-04169413ec23caecbb0d969307e33e9df8499ddcd1420305
ToppCellP03-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TST ANK3 RAB27B

5.08e-041704133fd37e9b377d6485cea1262c31a8507d18a78514
ToppCellnormal_Lung-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

VIPR1 RAB27B NTRK1

5.17e-04171413f49dfe11ae66d82125b577c48345a13683d7bb7b
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY1A1 VWA8 TRPC6

5.35e-04173413a37f38478473290fe35aea8684befc3bf95b161f
ToppCellIIH-CD8-naive_CD4|IIH / Condition, Cell_class and T cell subcluster

NPC1 MLF1 SLC38A5

5.35e-041734134f2843371d18af766c1892529ce286f56c956fde
ToppCellEpithelial-Epithelial-C_(AT2)|Epithelial / shred on cell class and cell subclass (v4)

NPC1 ANK3 RAB27B

5.35e-04173413f57cbf5bd2a9e5db47b4919e9cd5e50781c1a990
ToppCellE17.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TST ANK3 RAB27B

5.44e-0417441368914ec843f58ecff3e6412544a341daf8a01cac
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA2 CELF4 RAB27B

5.44e-04174413c58328c2f262506a4518f49f148e29874faf9171
ToppCellPosterior_cortex-Macroglia|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NPC1 ENPP6 TST

5.53e-041754138bc7a3856d04692989b2a1675ea6d9392261d55a
ToppCellCV-Mild-6|Mild / Virus stimulation, Condition and Cluster

VIPR1 DEPDC5 PPARA

5.53e-04175413c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT2|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TST ANK3 RAB27B

5.62e-04176413ac76f2cd6c63f30b38b89b58bad2baa4dde8ce3a
ToppCellB_cells-pDCs|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

NPC1 GUCY1A1 NME8

5.62e-04176413ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

NR3C2 ANK3 DNAJA4

5.62e-0417641336f77d878a53b30465b0dea8333a3865dba75613
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VAT1L NYNRIN TRPC6

5.72e-0417741375cb2067a3f2d1b5a964890b02b604d1e79bd163
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ENPP6 PPARA SLC25A48

5.72e-041774132f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPARA ANK3 RAB27B

5.81e-0417841376e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCelldroplet-Lung-30m-Epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPARA ANK3 RAB27B

5.81e-041784135442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ENPP6 PPARA SLC25A48

5.81e-0417841323a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPARA ANK3 RAB27B

5.81e-0417841382f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPARA ANK3 RAB27B

5.81e-04178413523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCelldroplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR3C2 AATK ANK3

5.81e-041784133e8aacb27ed1a3c3978e21dddddd0828f8000692
ToppCellfacs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR1 GUCY1A1 TRPC6

6.00e-04180413dfb8412e1e06fa7349e66eea2ef27d9ea98b7893
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VAT1L AATK ANK3

6.00e-04180413dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 F8 NYNRIN

6.00e-04180413423454e3390080ae03bb3cbb267255ebfe4df080
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AATK ANK3 TBCK

6.00e-04180413da723df348d7b8449bb1124f23fe6fa706412adb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VAT1L PPARA VWA8

6.00e-041804139e09b3dfe344b5d50520711513d389865d73a861
ToppCellfacs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR1 GUCY1A1 TRPC6

6.00e-041804130059e5acade6c895fd629767bea1c15f40b0d1b0
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AATK ANK3 TBCK

6.00e-041804135b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCell15-Distal-Epithelial-Epithelial|Distal / Age, Tissue, Lineage and Cell class

ANK3 SBF1 NTRK1

6.00e-0418041399e2db9ad8e09fedc3542233553acece69f579f1
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AATK ANK3 TBCK

6.00e-0418041350758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VAT1L AATK ANK3

6.00e-04180413d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 F8 NYNRIN

6.00e-04180413dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC38A5 GUCY1A1 RAB27B

6.10e-0418141314c2dd946e89ba578711c2d25935b6b3d319b701
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC38A5 GUCY1A1 RAB27B

6.10e-041814139dc0563453e24c9d1d975e2e0e1e272487e19908
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC38A5 GUCY1A1 RAB27B

6.10e-04181413c5843b89f3d362e236ff76c3279518a2fdfc1f75
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 F8 NYNRIN

6.10e-04181413fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC38A5 GUCY1A1 RAB27B

6.10e-04181413fcefb5902416c004631f4f8dd5c8f99fe3bd90bc
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY1A1 VWA8 TRPC6

6.20e-04182413be9c312a44868d4ee266a64d066feb8c5bce5687
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NPC1 GUCY1A1 NME8

6.20e-041824139bbe8062aa562dc3b9c299581faf6ebbcb72a9f7
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY1A1 VWA8 TRPC6

6.20e-0418241374dbb706bcaa0f8c922bf3b0424bce5bb27167fa
ToppCelldroplet-Kidney-nan-18m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLF1 NR3C2 AATK

6.20e-04182413e3248d108b51c49ca2c978636e13017e23b53860
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NPC1 GUCY1A1 NME8

6.20e-041824134602a98df7045e2c70b7560abfba9b444fbd5d30
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ENPP6 PPARA SLC25A48

6.30e-0418341385446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCellPND07-28-samps-Epithelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TST ANK3 RAB27B

6.30e-04183413a98f1d71d82ed6cca996f74352ab834fb6e95206
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

VIPR1 GUCY1A1 TRPC6

6.30e-04183413e3835db4795362b0442d5893baf2a78efcc20428
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AATK ANK3 RAB27B

6.30e-04183413876b4f128c2168fdae7488201ff44f19c06c8415
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AATK ANK3 RAB27B

6.30e-04183413b190b650e61b1b20baf5e42d04acac82d3fd1400
DiseaseSchizoaffective Disorder

PLA2G4A NTRK1

7.47e-0429412C0036337
DiseaseProteinuria

PPARA TRPC6

1.64e-0343412C0033687
Diseasemultiple sclerosis symptom measurement

NCOA2 SLC25A48

1.88e-0346412EFO_0803536
Diseasewellbeing measurement

NR3C2 CELF4 VAT1L AATK RAB27B

2.61e-03692415EFO_0007869

Protein segments in the cluster

PeptideGeneStartEntry
AFDLFMDPSFFQMDA

DOP1A

2111

Q5JWR5
SFSSPMDIFDMFFGG

DNAJA4

81

Q8WW22
DGEMFMRPGKLFDYF

CYC1

161

P08574
FRMAMGNPSEFFVDV

DVL3

701

Q92997
FPAFMEAFSSFNMLG

DNAJB8

141

Q8NHS0
IGEDKNSFFMEPMSF

CCNB3

556

Q8WWL7
TAFFRDAMGFLLMFD

RAB27B

86

O00194
TYMDSPRKDGAFFME

DEPDC5

1081

O75140
SASIMAAFMDNPFEF

NTRK1

371

P04629
PFMDGSYFSFMDDKD

NR3C2

451

P08235
MSPDTFLKGFAEFFL

OR14L1P

1

Q8NHC6
PDMSFFKMLFLPESA

F8

1111

P00451
EDEVFELFPMFMGGL

NLRX1

616

Q86UT6
FLMKVLEGMAFAGFV

SBF1

416

O95248
QGGDFMRFLPMFLSD

NPC1

991

O15118
MFGNADMNTFPTFKF

ATP5PF

81

P18859
MLASMIFRKEPFFHG

CSNK2A3

221

Q8NEV1
FPFHEGKMFEMTRSG

ANK3

3601

Q12955
MLASMIFRKEPFFHG

CSNK2A1

221

P68400
MDMRGIFLAFGPDFK

ENPP6

361

Q6UWR7
FFMGFMDSHRDAIPD

NYNRIN

1096

Q9P2P1
FCDIMEPKFDFAMKF

PPARA

351

Q07869
TFMAPDLFGSKFFMG

PLA2G4A

361

P47712
FFPALFATEKMFRML

TAS2R14

71

Q9NYV8
GPKFAFLSFVEAMSF

SLC6A16

476

Q9GZN6
DDDFPLMTAKAAFAM

AATK

1301

Q6ZMQ8
FMDFEGKTSFGMSVF

SLC38A5

41

Q8WUX1
RRESMFGFFKGMSFP

SLC25A48

51

Q6ZT89
KLAEMMFETFSVPGF

ACTRT1

121

Q8TDG2
EFGDAELMQMFLPFG

CELF4

431

Q9BZC1
ELMQMFLPFGFVSFD

CELF4

436

Q9BZC1
FSEFEHAMAKSPDFM

CIB4

161

A0PJX0
GPMMLEALDGFFFVV

NCOA2

116

Q15596
MFAFFPDNFKPEVKM

VIPR1

356

P32241
VAKFMDAFFPDFKKM

NME8

296

Q8N427
MAFAPMGPEASFFDV

SPO11

1

Q9Y5K1
MFRMLNSSFEDDPFF

MLF1

1

P58340
DDMSFSEAAAFPMNF

VAT1L

151

Q9HCJ6
MFPLKDAEMGAFTFF

TBCK

1

Q8TEA7
MRGPFMKFVAHAASF

TRPC6

436

Q9Y210
MPFMDFLTEDGFEKG

TST

211

Q16762
MNMTGKSGFFVDFFD

VWA8

1141

A3KMH1
FPFHFMFDKDMTILQ

GUCY1A1

286

Q02108