Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent conferring tensile strength	COL4A3 COL9A1 COL5A3 COL1A1	2.14e-05	46	71	4	GO:0030020
GeneOntologyCellularComponent	collagen trimer	COL4A3 COL9A1 COL5A3 COLEC10 COL1A1	1.23e-05	88	71	5	GO:0005581
GeneOntologyCellularComponent	complex of collagen trimers	COL4A3 COL5A3 COL1A1	4.78e-05	21	71	3	GO:0098644
Domain	Collagen	COL4A3 COL9A1 COL5A3 COLEC10 COL1A1	1.66e-05	85	70	5	IPR008160
Domain	Collagen	COL4A3 COL9A1 COL5A3 COLEC10 COL1A1	1.66e-05	85	70	5	PF01391
Domain	Fib_collagen_C	COL5A3 COL1A1	7.45e-04	11	70	2	IPR000885
Domain	COLFI	COL5A3 COL1A1	7.45e-04	11	70	2	PF01410
Domain	NC1_FIB	COL5A3 COL1A1	7.45e-04	11	70	2	PS51461
Domain	Fib_collagen_C	COL5A3 COL1A1	7.45e-04	11	70	2	PD002078
Domain	COLFI	COL5A3 COL1A1	7.45e-04	11	70	2	SM00038
Domain	Rib_L2_dom2	HERC2 MRPL2	2.04e-03	18	70	2	IPR014722
Domain	-	HERC2 MRPL2	2.04e-03	18	70	2	2.30.30.30
Domain	TSPN	COL9A1 COL5A3	3.33e-03	23	70	2	SM00210
Pathway	REACTOME_COLLAGEN_CHAIN_TRIMERIZATION	COL4A3 COL9A1 COL5A3 COL1A1	1.89e-05	41	55	4	MM15538
Pathway	REACTOME_COLLAGEN_CHAIN_TRIMERIZATION	COL4A3 COL9A1 COL5A3 COL1A1	2.51e-05	44	55	4	M27812
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL4A3 COL9A1 COL5A3 COL1A1	4.18e-05	50	55	4	MM14796
Pathway	REACTOME_NCAM1_INTERACTIONS	COL4A3 COL9A1 COL5A3	6.11e-05	20	55	3	MM15061
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL4A3 COL9A1 COL5A3 COL1A1	9.18e-05	61	55	4	M27103
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL4A3 COL9A1 COL5A3 COL1A1	9.18e-05	61	55	4	MM14637
Pathway	REACTOME_COLLAGEN_DEGRADATION	COL4A3 COL9A1 COL5A3 COL1A1	1.11e-04	64	55	4	M26953
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL4A3 COL9A1 COL5A3 COL1A1	1.32e-04	67	55	4	M26999
Pathway	REACTOME_ECM_PROTEOGLYCANS	COL4A3 COL9A1 COL5A3 COL1A1	2.16e-04	76	55	4	M27219
Pathway	REACTOME_COLLAGEN_FORMATION	COL4A3 COL9A1 COL5A3 COL1A1	2.16e-04	76	55	4	MM14573
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL4A3 COL9A1 COL5A3 COL1A1	2.16e-04	76	55	4	MM14867
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	COL4A3 COL5A3 COL1A1	2.57e-04	32	55	3	MM14924
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL4A3 COL9A1 COL5A3 COL1A1	3.32e-04	85	55	4	M16441
Pathway	REACTOME_COLLAGEN_FORMATION	COL4A3 COL9A1 COL5A3 COL1A1	4.13e-04	90	55	4	M631
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	COL4A3 COL9A1 COL5A3	4.30e-04	38	55	3	MM14969
Pathway	BIOCARTA_TCRA_PATHWAY	CD247 ZAP70	5.29e-04	9	55	2	MM1429
Pathway	REACTOME_NCAM1_INTERACTIONS	COL4A3 COL9A1 COL5A3	5.79e-04	42	55	3	M7169
Pathway	WP_NEURODEGENERATION_WITH_BRAIN_IRON_ACCUMULATION_NBIA_SUBTYPES_PATHWAY	PANK2 ULK1 ATG2A	6.65e-04	44	55	3	M39602
Pathway	PID_SYNDECAN_1_PATHWAY	COL4A3 COL9A1 COL1A1	7.58e-04	46	55	3	M198
Pathway	REACTOME_ECM_PROTEOGLYCANS	COL9A1 COL5A3 COL1A1	8.07e-04	47	55	3	MM14925
Pathway	REACTOME_COLLAGEN_DEGRADATION	COL4A3 COL5A3 COL1A1	1.15e-03	53	55	3	MM14566
Pathway	BIOCARTA_TCRA_PATHWAY	CD247 ZAP70	1.32e-03	14	55	2	M10765
Pathway	REACTOME_SIGNALING_BY_PDGF	COL4A3 COL9A1 COL5A3	1.42e-03	57	55	3	MM14713
Pathway	REACTOME_SIGNALING_BY_PDGF	COL4A3 COL9A1 COL5A3	1.49e-03	58	55	3	M2049
Pathway	PID_ARF6_DOWNSTREAM_PATHWAY	PIP5K1A PLD2	1.52e-03	15	55	2	M120
Pathway	REACTOME_ANCHORING_FIBRIL_FORMATION	COL4A3 COL1A1	1.52e-03	15	55	2	M27161
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	COL4A3 COL5A3 COL1A1	1.57e-03	59	55	3	M27218
Pathway	BIOCARTA_CSK_PATHWAY	CD247 ZAP70	1.73e-03	16	55	2	MM1340
Pathway	REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE	CD247 ZAP70	1.73e-03	16	55	2	MM14808
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	COL4A3 COL9A1 COL5A3	1.89e-03	63	55	3	M11187
Pathway	WP_IRON_METABOLISM_DISORDERS	PANK2 HEPH	1.96e-03	17	55	2	M48053
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL4A3 COL9A1 COL5A3 COL1A1	2.15e-03	140	55	4	M587
Pathway	REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS	COL4A3 COL1A1	2.20e-03	18	55	2	M27164
Pathway	REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS	COL4A3 COL1A1	2.20e-03	18	55	2	MM14882
Pubmed	The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase.	DDX17 HNRNPM EWSR1 PPP6R1 NUP160 RBM39 GNL3	3.47e-07	220	71	7	34091597
Pubmed	Single-Cell Characterization of the Frizzled 5 (Fz5) Mutant Mouse and Human Persistent Fetal Vasculature (PFV).	SOX10 FZD5 COL1A1	4.53e-07	8	71	3	36867129
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	DHX36 DDX17 SPOUT1 RBM33 HNRNPM MRPS11 PDAP1 EWSR1 RBM39 GNL3 MRPL2	7.08e-07	807	71	11	22681889
Pubmed	The immune molecule CD3zeta and its downstream effectors ZAP-70/Syk mediate ephrin signaling in neurons to regulate early neuritogenesis.	CD247 ZAP70	4.11e-06	2	71	2	21895656
Pubmed	Interaction between the SH2 domains of ZAP-70 and the tyrosine-based activation motif 1 sequence of the zeta subunit of the T-cell receptor.	CD247 ZAP70	4.11e-06	2	71	2	9185620
Pubmed	Gene clusters based on OLIG2 and CD276 could distinguish molecular profiling in glioblastoma.	OLIG2 CD276	4.11e-06	2	71	2	34565408
Pubmed	Activation of Zap-70 tyrosine kinase due to a structural rearrangement induced by tyrosine phosphorylation and/or ITAM binding.	CD247 ZAP70	4.11e-06	2	71	2	10704231
Pubmed	Differential T cell signaling induced by antagonist peptide-MHC complexes and the associated phenotypic responses.	CD247 ZAP70	4.11e-06	2	71	2	9036949
Pubmed	Increased Zap-70 association with CD3zeta in CD4 T cells from old mice.	CD247 ZAP70	4.11e-06	2	71	2	9878110
Pubmed	TCR/CD3 down-modulation and zeta degradation are regulated by ZAP-70.	CD247 ZAP70	4.11e-06	2	71	2	12165490
Pubmed	A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70.	CD247 ZAP70	4.11e-06	2	71	2	26783323
Pubmed	ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity.	CD247 ZAP70	4.11e-06	2	71	2	7528772
Pubmed	Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases.	CD247 ZAP70	4.11e-06	2	71	2	7509083
Pubmed	Mechanism of activation for Zap-70 catalytic activity.	CD247 ZAP70	4.11e-06	2	71	2	8901551
Pubmed	SOX10 and Olig2 as negative markers for the diagnosis of ependymomas: An immunohistochemical study of 98 glial tumors.	SOX10 OLIG2	4.11e-06	2	71	2	26287936
Pubmed	Peptide microarrays for the detection of molecular interactions in cellular signal transduction.	CD247 ZAP70	4.11e-06	2	71	2	15832366
Pubmed	Accelerated generation of oligodendrocyte progenitor cells from human induced pluripotent stem cells by forced expression of Sox10 and Olig2.	SOX10 OLIG2	4.11e-06	2	71	2	27785726
Pubmed	A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex.	SOX10 SATB2 OLIG2	4.48e-06	16	71	3	38713624
Pubmed	Development of T cells expressing an altered TCR complex.	CD247 ZAP70	1.23e-05	3	71	2	14515253
Pubmed	One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2.	SOX10 OLIG2	1.23e-05	3	71	2	33770499
Pubmed	Cbl promotes ubiquitination of the T cell receptor zeta through an adaptor function of Zap-70.	CD247 ZAP70	1.23e-05	3	71	2	11353765
Pubmed	HDAC6 deacetylase activity links the tubulin cytoskeleton with immune synapse organization.	CD247 ZAP70	1.23e-05	3	71	2	15084271
Pubmed	TREM-2 promotes Th1 responses by interacting with the CD3ζ-ZAP70 complex following Mycobacterium tuberculosis infection.	CD247 ZAP70	1.23e-05	3	71	2	34623322
Pubmed	Characteristics of TCRζ, ZAP-70, and FcɛRIγ gene expression in patients with T- and NK/T-cell lymphoma.	CD247 ZAP70	1.23e-05	3	71	2	25513989
Pubmed	The transmembrane adaptor protein SIT inhibits TCR-mediated signaling.	CD247 ZAP70	1.23e-05	3	71	2	21957439
Pubmed	Tandem SH2 domains of ZAP-70 bind to T cell antigen receptor zeta and CD3 epsilon from activated Jurkat T cells.	CD247 ZAP70	1.23e-05	3	71	2	8366117
Pubmed	Regulation of the p70zap tyrosine protein kinase in T cells by the CD45 phosphotyrosine phosphatase.	CD247 ZAP70	1.23e-05	3	71	2	7737297
Pubmed	A deficient translocation of CD3ζ, ZAP-70 and Grb2 to lipid raft, as a hallmark of defective adaptive immune response during chronic hepatitis B infection.	CD247 ZAP70	1.23e-05	3	71	2	23916875
Pubmed	Quantitative phosphoproteome analysis unveils LAT as a modulator of CD3ζ and ZAP-70 tyrosine phosphorylation.	CD247 ZAP70	1.23e-05	3	71	2	24204825
Pubmed	Interaction of the type Ialpha PIPkinase with phospholipase D: a role for the local generation of phosphatidylinositol 4, 5-bisphosphate in the regulation of PLD2 activity.	PIP5K1A PLD2	1.23e-05	3	71	2	11032811
Pubmed	Gain of Olig2 function in oligodendrocyte progenitors promotes remyelination.	SOX10 OLIG2	1.23e-05	3	71	2	25564492
Pubmed	Sox10 directs neural stem cells toward the oligodendrocyte lineage by decreasing Suppressor of Fused expression.	SOX10 OLIG2	1.23e-05	3	71	2	21098272
Pubmed	Signal transduction in primary human T lymphocytes in altered gravity during parabolic flight and clinostat experiments.	CD247 ZAP70	1.23e-05	3	71	2	25661802
Pubmed	Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors.	SOX10 SATB2 OLIG2	2.05e-05	26	71	3	30538199
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	DHX36 ACAP1 DDX17 HNRNPM MRPS11 PIP5K1A EWSR1 RBM39 GNL3 COL1A1 MRPL2	2.10e-05	1153	71	11	29845934
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	DHX36 PIP5K1A NCKAP5 ZSWIM6 TRIM3 USP21	2.43e-05	281	71	6	24163370
Pubmed	Inhibition of platelet-derived growth factor-induced cell growth signaling by a short interfering RNA for EWS-Fli1 via down-regulation of phospholipase D2 in Ewing sarcoma cells.	EWSR1 PLD2	2.46e-05	4	71	2	15919668
Pubmed	Csk is constitutively associated with a 60-kDa tyrosine-phosphorylated protein in human T cells.	CD247 ZAP70	2.46e-05	4	71	2	8621646
Pubmed	PTPH1 is a predominant protein-tyrosine phosphatase capable of interacting with and dephosphorylating the T cell receptor zeta subunit.	CD247 ZAP70	2.46e-05	4	71	2	14672952
Pubmed	A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signaling.	CD247 ZAP70	2.46e-05	4	71	2	11891219
Pubmed	Association of TCR/CD3, PTPN22, CD28 and ZAP70 gene polymorphisms with type 1 diabetes risk in Tunisian population: family based association study.	CD247 ZAP70	2.46e-05	4	71	2	25448703
Pubmed	Tyrosine phosphorylation and recruitment of ZAP-70 to the CD3-TCR complex are defective after CD2 stimulation.	CD247 ZAP70	2.46e-05	4	71	2	8906806
Pubmed	Alternative modes of binding of proteins with tandem SH2 domains.	CD247 ZAP70	2.46e-05	4	71	2	10752619
Pubmed	Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function.	ZBTB16 COL1A1	2.46e-05	4	71	2	25848867
Pubmed	Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs.	COL9A1 COL1A1	2.46e-05	4	71	2	2054384
Pubmed	Collagen family of proteins.	COL5A3 COL1A1	2.46e-05	4	71	2	1916105
Pubmed	Cell-type dependent enhancer binding of the EWS/ATF1 fusion gene in clear cell sarcomas.	SOX10 COL1A1	2.46e-05	4	71	2	31488818
Pubmed	Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors.	SOX10 OLIG2	2.46e-05	4	71	2	10719889
Pubmed	Human transcription factor protein interaction networks.	SOX10 DHX36 KLF12 SATB2 RBM33 MRPS11 ETV3 EWSR1 PPP6R1 HERC2 GNL3 MRPL2	3.00e-05	1429	71	12	35140242
Pubmed	DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.	DDX17 HNRNPM AFDN EWSR1	3.41e-05	89	71	4	22446626
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	RBM33 HNRNPM ETV3 EWSR1 NUP160	3.47e-05	180	71	5	35198878
Pubmed	Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases.	CD247 ZAP70	4.09e-05	5	71	2	8648092
Pubmed	Staging and resetting T cell activation in SMACs.	CD247 ZAP70	4.09e-05	5	71	2	12244310
Pubmed	Transcription-dependent nucleolar cap localization and possible nuclear function of DExH RNA helicase RHAU.	DHX36 DDX17	4.09e-05	5	71	2	18279852
Pubmed	RhoH regulates subcellular localization of ZAP-70 and Lck in T cell receptor signaling.	CD247 ZAP70	4.09e-05	5	71	2	21103055
Pubmed	EWS/ATF1 expression induces sarcomas from neural crest-derived cells in mice.	EWSR1 COL1A1	4.09e-05	5	71	2	23281395
Pubmed	The myelination-associated G protein-coupled receptor 37 is regulated by Zfp488, Nkx2.2, and Sox10 during oligodendrocyte differentiation.	SOX10 OLIG2	4.09e-05	5	71	2	38546197
Pubmed	From classical to current: analyzing peripheral nervous system and spinal cord lineage and fate.	ZBTB16 OLIG2	4.09e-05	5	71	2	25446276
Pubmed	Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling.	CD247 ZAP70	4.09e-05	5	71	2	10662792
Pubmed	K33-linked polyubiquitination of T cell receptor-zeta regulates proteolysis-independent T cell signaling.	CD247 ZAP70	4.09e-05	5	71	2	20637659
Pubmed	Ligation of the T-cell antigen receptor (TCR) induces association of hSos1, ZAP-70, phospholipase C-gamma 1, and other phosphoproteins with Grb2 and the zeta-chain of the TCR.	CD247 ZAP70	4.09e-05	5	71	2	7629168
Pubmed	The Shc family protein adaptor, Rai, negatively regulates T cell antigen receptor signaling by inhibiting ZAP-70 recruitment and activation.	CD247 ZAP70	4.09e-05	5	71	2	22242145
Pubmed	Transcription factors Bcl11a and Bcl11b are required for the production and differentiation of cortical projection neurons.	SOX10 SATB2 OLIG2	4.66e-05	34	71	3	34963132
Pubmed	Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy.	SLC25A46 EWSR1 ULK1 ATG2A	5.18e-05	99	71	4	31723608
Pubmed	Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons.	SATB2 ZBTB16	6.13e-05	6	71	2	31027502
Pubmed	Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif.	CD247 ZAP70	6.13e-05	6	71	2	8196616
Pubmed	Sox group E gene expression distinguishes different types and maturational stages of glial cells in developing chick and mouse.	SOX10 OLIG2	6.13e-05	6	71	2	15878625
Pubmed	ColVa1 and ColXIa1 are required for myocardial morphogenesis and heart valve development.	COL9A1 COL1A1	6.13e-05	6	71	2	17029294
Pubmed	Light-Controlled Affinity Purification of Protein Complexes Exemplified by the Resting ZAP70 Interactome.	CD247 ZAP70	6.13e-05	6	71	2	30863395
Pubmed	PDK1 regulates the generation of oligodendrocyte precursor cells at an early stage of mouse telencephalic development.	SOX10 OLIG2	6.13e-05	6	71	2	22390626
Pubmed	Retarded skeletal development in transgenic mice with a type II collagen mutation.	COL9A1 COL1A1	6.13e-05	6	71	2	8952549
Pubmed	Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules.	CD247 ZAP70	6.13e-05	6	71	2	11572860
Pubmed	Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon.	SOX10 OLIG2	6.13e-05	6	71	2	11493571
Pubmed	Induction of oligodendrocyte differentiation by Olig2 and Sox10: evidence for reciprocal interactions and dosage-dependent mechanisms.	SOX10 OLIG2	6.13e-05	6	71	2	17098222
Pubmed	Perturbed regulation of ZAP-70 and sustained tyrosine phosphorylation of LAT and SLP-76 in c-Cbl-deficient thymocytes.	CD247 ZAP70	6.13e-05	6	71	2	10358158
Pubmed	Cranial nerve fasciculation and Schwann cell migration are impaired after loss of Npn-1.	SOX10 OLIG2	6.13e-05	6	71	2	21925156
Pubmed	CD38 signaling in T cells is initiated within a subset of membrane rafts containing Lck and the CD3-zeta subunit of the T cell antigen receptor.	CD247 ZAP70	6.13e-05	6	71	2	14523017
Pubmed	Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation.	SOX10 OLIG2	6.13e-05	6	71	2	26955760
Pubmed	SLAP, a dimeric adapter protein, plays a functional role in T cell receptor signaling.	CD247 ZAP70	6.13e-05	6	71	2	10449770
Pubmed	YAP Mediates Hair Cell Regeneration in Balance Organs of Chickens, But LATS Kinases Suppress Its Activity in Mice.	SOX10 COL1A1	6.13e-05	6	71	2	32341094
Pubmed	Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.	HNRNPM EWSR1 NUP160 RBM39	6.28e-05	104	71	4	26167872
Pubmed	A SMAD1/5-YAP signalling module drives radial glia self-amplification and growth of the developing cerebral cortex.	SOX10 SATB2 OLIG2	6.53e-05	38	71	3	32541003
Pubmed	ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.	METTL25B DDX17 HNRNPM EWSR1 ZSWIM6 RBM39	6.57e-05	336	71	6	31253590
Pubmed	Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.	DHX36 DDX17 HNRNPM EWSR1 RBM39	6.58e-05	206	71	5	22174317
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	DHX36 DDX17 HNRNPM MRPS11 PIP5K1A EWSR1 RBM39 GNL3	7.23e-05	678	71	8	30209976
Pubmed	Genome-wide association analysis identifies 13 new risk loci for schizophrenia.	KMT5A TSNARE1 ZSWIM6 GNL3	7.55e-05	109	71	4	23974872
Pubmed	Cellular RNA binding proteins NS1-BP and hnRNP K regulate influenza A virus RNA splicing.	DHX36 DDX17 HNRNPM	7.63e-05	40	71	3	23825951
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	DHX36 DDX17 HNRNPM MRPS11 PIP5K1A EWSR1 PPP6R1 DRAP1 NUP160 GNL3 MRPL2	7.91e-05	1335	71	11	29229926
Pubmed	Lck availability during thymic selection determines the recognition specificity of the T cell repertoire.	CD247 ZAP70	8.57e-05	7	71	2	24034254
Pubmed	Mutation in type II collagen gene disturbs spinal development and gene expression patterns in transgenic Del1 mice.	COL9A1 COL1A1	8.57e-05	7	71	2	9426396
Pubmed	Macroglial plasticity and the origins of reactive astroglia in experimental autoimmune encephalomyelitis.	SOX10 OLIG2	8.57e-05	7	71	2	21849552
Pubmed	Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2.	CD247 ZAP70	8.57e-05	7	71	2	9047237
Pubmed	Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.	DHX36 DDX17 HNRNPM RBM39 GNL3	9.56e-05	223	71	5	20020773
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	DHX36 DDX17 HNRNPM MRPS11 PIP5K1A RBM39 GNL3 MRPL2	1.02e-04	713	71	8	29802200
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	DDX17 SPOUT1 RBM33 MRPS11 PDAP1 EWSR1 GNL3 MRPL2	1.13e-04	723	71	8	34133714
Pubmed	Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling.	CD247 ZAP70	1.14e-04	8	71	2	8176201
Pubmed	The pro-alpha2(XI) collagen gene is expressed in odontoblasts.	COL5A3 COL1A1	1.14e-04	8	71	2	20059976
Pubmed	Phosphorylation regulates OLIG2 cofactor choice and the motor neuron-oligodendrocyte fate switch.	SOX10 OLIG2	1.14e-04	8	71	2	21382552
Pubmed	Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy.	SOX10 OLIG2	1.14e-04	8	71	2	15102707
Pubmed	Short amino acid sequences derived from C1q receptor (C1q-R) show homology with the alpha chains of fibronectin and vitronectin receptors and collagen type IV.	COL4A3 COL1A1	1.14e-04	8	71	2	1377218
GeneFamily	Collagens	COL4A3 COL9A1 COL5A3 COL1A1	1.61e-05	46	60	4	490
Coexpression	NABA_COLLAGENS	COL4A3 COL9A1 COL5A3 COL1A1	5.63e-06	43	71	4	MM17060
Coexpression	NABA_COLLAGENS	COL4A3 COL9A1 COL5A3 COL1A1	6.18e-06	44	71	4	M3005
ToppCell	moderate-Lymphoid-Treg\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KLF12 ACAP1 CD247 ZBTB16 AKNA COL5A3 ZAP70	2.44e-08	192	71	7	e370ff5aaff7b7042ba9aaf93de43aa563b8b9f9
ToppCell	moderate-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ACAP1 CD247 ZBTB16 DDX17 COL5A3 ZAP70 RBM39	2.81e-08	196	71	7	9152f4a8a27ff4ee28f231c5ad00eb2edd9ea6da
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD8+_T-MAIT-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ACAP1 CD247 ZBTB16 KCNQ3 COL5A3 ZAP70	2.71e-07	166	71	6	bb93db4613c067c56614ab1ca39e73ee46484387
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD8+_T-MAIT\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ACAP1 CD247 ZBTB16 KCNQ3 COL5A3 ZAP70	2.71e-07	166	71	6	c1f17a028bb27b8f202bcfffa7de7373b1cdd990
ToppCell	Adult-Immune-natural_killer_cell-D231\|Adult / Lineage, Cell type, age group and donor	KLF12 ACAP1 CD247 AKNA ZNF80 ZAP70	4.65e-07	182	71	6	dbf47bf4754d8ec3bc3ab1d5be7a6c47a7afbf43
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-ILCP\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A3 ACAP1 CD247 ZBTB16 MYO18B ZAP70	5.28e-07	186	71	6	428b4cbee3d3ab666cab2fc2d9c815318359e458
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A3 SOX10 COL9A1 COL5A3 NCKAP5 OLIG2	5.44e-07	187	71	6	daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A3 SOX10 COL9A1 COL5A3 NCKAP5 OLIG2	5.44e-07	187	71	6	5b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL5A3 NCKAP5 COX4I2 HEPH CD276 COL1A1	5.79e-07	189	71	6	1ff4f8da572bdc6356e9df9f41a7f62c81d4c570
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLF12 ACAP1 CD247 AKNA ZAP70 RBM39	5.97e-07	190	71	6	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	Adult-Immune-natural_killer_cell\|Adult / Lineage, Cell type, age group and donor	KLF12 ACAP1 CD247 AKNA ZNF80 ZAP70	6.16e-07	191	71	6	758ec27e47d7662a5175305e98a1506c6859dbf7
ToppCell	NS-moderate-d_16-33-Lymphoid-Treg\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KLF12 ACAP1 CD247 AKNA COL5A3 ZAP70	6.35e-07	192	71	6	48d557071bad80edd3ec6e5ad8dcd97037da9553
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-gd_T\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ACAP1 CD247 ZBTB16 AKNA ATG2A ZAP70	7.16e-07	196	71	6	aec2b11a6048048820271266fdc8b8d806da9993
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-gd_T-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ACAP1 CD247 ZBTB16 AKNA ATG2A ZAP70	7.16e-07	196	71	6	aa0dc04f94a575cd442ee473b75a4f54268e4105
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-gd_T-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ACAP1 CD247 ZBTB16 AKNA ATG2A ZAP70	7.16e-07	196	71	6	502834a16d5ada93af7ab9af0c3dc652086964bd
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-gd_T\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ACAP1 CD247 ZBTB16 AKNA ATG2A ZAP70	7.16e-07	196	71	6	ae9bf04531b9bda819608d90736c4405a6c3df41
ToppCell	Control-Lymphoid_T/NK-gd_T\|Control / Disease group, lineage and cell class	ACAP1 CD247 ZBTB16 AKNA ATG2A ZAP70	7.16e-07	196	71	6	98b11aada6bc5d928ef618573dc912d4d74a1092
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-T-T_CD8-CD8_GZMK+\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KLF12 ACAP1 CD247 AKNA ZNF80 ZAP70	7.38e-07	197	71	6	99f29fa06c96c399a48ea1fc82fbedd4f4256a99
ToppCell	mild_COVID-19_(asymptomatic)-CD8+_Tem\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	ACAP1 CD247 AKNA ZNF80 ATG2A ZAP70	7.60e-07	198	71	6	a7519bbbb67d319635ddbe05a2a154c46b77ce87
ToppCell	(220)_CD8+_Cytotoxic_T_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	ACAP1 CD247 ZBTB16 COL5A3 ATG2A ZAP70	7.60e-07	198	71	6	2af389b8ea5767ba56fe64d719afe5be3f9a43ec
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_GZMK+\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KLF12 ACAP1 CD247 AKNA ZNF80 ZAP70	7.83e-07	199	71	6	09e0b45529fa9d5fc86da1747b3fb3a238a09aa6
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KLF12 ACAP1 CD247 AKNA ZNF80 ZAP70	7.83e-07	199	71	6	b947ecaf912d97869f6df32736b8c2b2dd695d66
ToppCell	Control-Control-Lymphocyte-T/NK-gd_T\|Control / Disease, condition lineage and cell class	ACAP1 CD247 ZBTB16 AKNA ATG2A ZAP70	8.06e-07	200	71	6	88e502c141bbb73e62aa5830d24bd645376e5f3a
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	KLF12 ACAP1 CD247 AKNA ZAP70	4.34e-06	151	71	5	512f7f37ddc8dfa1906f7fff92b571929236c9ea
ToppCell	facs-SCAT-Fat-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAP1 CD247 AKNA BSN ZAP70	4.93e-06	155	71	5	93513bab53b40e9c3c91ab8e3316ea00a4f66cd2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZBTB16 TSNARE1 APC2 TRIM3 COL1A1	5.41e-06	158	71	5	4d997efc36fd8946775fe74dd9ac9ccd5ade64ff
ToppCell	Bronchial-10x5prime-Stromal-Schwann\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SOX10 MICALL2 COL5A3 HEPH COL1A1	6.11e-06	162	71	5	afffecc6c504930554aafc12c5bffa53e3c5b016
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	KLF12 ACAP1 CD247 ZBTB16 ZNF80	7.09e-06	167	71	5	94642b3dae035fedb6e8b9745f440096a4539f3c
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell-NK\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	KLF12 ACAP1 CD247 ZBTB16 ZNF80	7.09e-06	167	71	5	42b299273a6c72a625b204d55f4f3c4eebd6d185
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell-NK-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KLF12 ACAP1 CD247 ZBTB16 ZNF80	7.09e-06	167	71	5	ecf5bc634e1e01efd783617eb81d1704e903ea21
ToppCell	CTRL-Lymphoid-T_cell_&_NK_cell\|CTRL / Disease state, Lineage and Cell class	KLF12 ACAP1 CD247 ZNF80 ZAP70	9.40e-06	177	71	5	e73d8e78a96b63e27a8a7694c62b3c44ec7ecfe6
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACAP1 CD247 AKNA ZNF80 ZAP70	9.66e-06	178	71	5	c4a2e9a440e941e82bb35abefa054e07ad250d45
ToppCell	Control-T/NK-NK\|Control / Disease group,lineage and cell class （2021.01.30）	KLF12 ACAP1 CD247 ZBTB16 ZNF80	9.66e-06	178	71	5	079fd19bdeed86bf985c4083af432432d66ad546
ToppCell	IIF-Lymphocyte-T_NK-gdT\|IIF / Disease, Lineage and Cell Type	ACAP1 CD247 ZBTB16 COL5A3 ATG2A	9.66e-06	178	71	5	3344d1328fd9c570c3a4b2629edec627a442d0e0
ToppCell	Mild-Lymphoid-T-innate_T\|Mild / Condition, Lineage, Cell class and cell subclass	ACAP1 CD247 ZBTB16 COL5A3 ZAP70	9.92e-06	179	71	5	abc0fbe101a464a2c85755a974a3d5c2b968fe46
ToppCell	Adult-Immune-natural_killer_cell-D175\|Adult / Lineage, Cell type, age group and donor	KLF12 ACAP1 CD247 AKNA ZAP70	1.02e-05	180	71	5	fc59e28f39e7d4fb1bcc7205202cf39224b70d7b
ToppCell	Adult-Immune-T_lymphocyte-D122\|Adult / Lineage, Cell type, age group and donor	KLF12 ACAP1 CD247 AKNA ZAP70	1.02e-05	180	71	5	06c371d0f0c5a7b234dd143e98800e19af95a8b5
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A3 SOX10 COL9A1 NCKAP5 OLIG2	1.08e-05	182	71	5	8a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACAP1 CD247 ZBTB16 AKNA ZAP70	1.08e-05	182	71	5	feda21c92d30848de70c8b404eaabbca3f5e894d
ToppCell	IPF-Lymphoid-ILC_A\|World / Disease state, Lineage and Cell class	ACAP1 CD247 ZBTB16 AKNA ZAP70	1.08e-05	182	71	5	f91bb45baaec76cb3bb26eedbcf0709b2492e93f
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A3 SOX10 COL9A1 NCKAP5 OLIG2	1.08e-05	182	71	5	e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACAP1 CD247 ZBTB16 MYO18B ZAP70	1.10e-05	183	71	5	c7fedb5b0c1f17b3391ce1c4a6bfca7615c359c5
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACAP1 CD247 ZBTB16 MYO18B ZAP70	1.10e-05	183	71	5	d4a558bc0b8e11be195a7da1468ab38eb477117d
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 APC2 COL5A3 CD276 COL1A1	1.16e-05	185	71	5	ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_bright-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ACAP1 CD247 ZBTB16 ATG2A RBM39	1.16e-05	185	71	5	3b2da51aec057b462749ae39afb8f253afcf38d5
ToppCell	Control-T_cells-CD8+_T_cells\|Control / group, cell type (main and fine annotations)	KLF12 ACAP1 CD247 AKNA ZAP70	1.16e-05	185	71	5	02ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell	tumor_Lung-T/NK_cells-Cytotoxic_CD8+_T\|tumor_Lung / Location, Cell class and cell subclass	ACAP1 CD247 AKNA ATG2A ZAP70	1.23e-05	187	71	5	530839fb53bb285b22919fde6aa16ce1399615ef
ToppCell	Control-T_cells\|Control / group, cell type (main and fine annotations)	KLF12 ACAP1 CD247 AKNA ZAP70	1.23e-05	187	71	5	f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCell	COPD-Lymphoid-NK\|COPD / Disease state, Lineage and Cell class	KLF12 CD247 ZBTB16 AKNA ZAP70	1.26e-05	188	71	5	c9a227c8e71b69929d43e9afb8306a95c8163778
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KLF12 ACAP1 CD247 AKNA ZAP70	1.29e-05	189	71	5	df30478b288084a1bd48f660409dcc784040897c
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-NK_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACAP1 CD247 ZBTB16 AKNA ZAP70	1.29e-05	189	71	5	5a9c3c61998efc40a5d2042e0f568b52103734a9
ToppCell	COVID-19-T_cells-CD8+_T_cells\|COVID-19 / group, cell type (main and fine annotations)	KLF12 ACAP1 CD247 AKNA ZAP70	1.29e-05	189	71	5	2c018d6120f65f0b2704b483bc9da1c0984872e3
ToppCell	COPD-Lymphoid-NK\|World / Disease state, Lineage and Cell class	KLF12 CD247 ZBTB16 AKNA ZAP70	1.29e-05	189	71	5	c0ac160fa7e68b92414fb1600abcac8ad1a42232
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-Activated_T\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACAP1 CD247 ZBTB16 AKNA ZAP70	1.29e-05	189	71	5	c38157c8cf5c0c1f560011ef5cc5892a049ee2b7
ToppCell	Fetal_29-31_weeks-Immune-natural_killer_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ACAP1 CD247 ZBTB16 AKNA ZAP70	1.29e-05	189	71	5	c604da558c9f4055fb36218452463539f2a73223
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMK+-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ACAP1 CD247 AKNA ATG2A ZAP70	1.29e-05	189	71	5	f1129eb122bbc051457c5545f1a267beb988b0f2
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMK+\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ACAP1 CD247 AKNA ATG2A ZAP70	1.29e-05	189	71	5	0b012ee301419fa9ccc387c3ff66c2344b349a97
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	ACAP1 CD247 DDX17 ZAP70 RBM39	1.29e-05	189	71	5	0e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCell	Control-Lymphoid-T_Cytotoxic\|World / Disease state, Lineage and Cell class	KLF12 ACAP1 CD247 AKNA ZAP70	1.29e-05	189	71	5	ee4c1d930534788a7759d92dc8ff9c62e6ee2301
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KLF12 CD247 ZBTB16 ATG2A ZAP70	1.32e-05	190	71	5	05e6af222d0ad97cb69f399a96c9038f9dd989b9
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-gdT\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLF12 ACAP1 CD247 AKNA ZAP70	1.32e-05	190	71	5	116314a27064d3005d950c9a9163b79ea438707b
ToppCell	IPF-Lymphoid-T_Cytotoxic\|IPF / Disease state, Lineage and Cell class	KLF12 ACAP1 CD247 AKNA ZAP70	1.32e-05	190	71	5	e5d0186bfb416a3eda76ac12b9379650afb6f409
ToppCell	Control-T_cells-CD4+_T_cells\|Control / group, cell type (main and fine annotations)	KLF12 ACAP1 CD247 AKNA ZAP70	1.32e-05	190	71	5	0733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCell	ASK428-Immune-NK_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	ACAP1 CLUAP1 CD247 EWSR1 ZAP70	1.32e-05	190	71	5	d649f7e17c4227787465dfc02037f791ff85378b
ToppCell	Control-Lymphoid-NK\|Control / Disease state, Lineage and Cell class	KLF12 CD247 ZBTB16 AKNA ZAP70	1.32e-05	190	71	5	f7bd8521a40ac30a64dc439f17e2f6c7d021ef65
ToppCell	metastatic_Brain-T/NK_cells-Exhausted_CD8+_T\|metastatic_Brain / Location, Cell class and cell subclass	ACAP1 CD247 AKNA ATG2A ZAP70	1.36e-05	191	71	5	b98367fdb56ccb335d61035e69cd43c61a7fa816
ToppCell	Adult-Immune-T_lymphocyte-D175\|Adult / Lineage, Cell type, age group and donor	KLF12 ACAP1 CD247 AKNA ZAP70	1.36e-05	191	71	5	0b84fd1dc68146d9f72422b102744d2847f5ecb2
ToppCell	COVID-19-lung-CD4+_Treg\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KLF12 ACAP1 CD247 AKNA ZAP70	1.36e-05	191	71	5	5a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCell	Control-Lymphoid-ILC_A\|Control / Disease state, Lineage and Cell class	ACAP1 CD247 ZBTB16 AKNA ZAP70	1.36e-05	191	71	5	1ca73582dc3d28322b5ee841010067589d848acc
ToppCell	Control-Lymphoid-T_Cytotoxic\|Control / Disease state, Lineage and Cell class	KLF12 ACAP1 CD247 AKNA ZAP70	1.36e-05	191	71	5	03b5c5e0941c3402ab3f48cbf3da2a027d110421
ToppCell	COVID-19-lung-CD8+_T_cells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KLF12 ACAP1 CD247 AKNA ZAP70	1.36e-05	191	71	5	543f8ae07cc2e6950c888115a5ca9445e3c0f618
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KLF12 ACAP1 CD247 AKNA ZAP70	1.36e-05	191	71	5	c7be771543089fc94e5c62fd22f745189642aec3
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KLF12 ACAP1 CD247 AKNA ZAP70	1.36e-05	191	71	5	6345c1aa0fd2f9f2154a44f9393bf7c72bb1f44e
ToppCell	COVID-19-T_cells-CD4+_T_cells\|COVID-19 / group, cell type (main and fine annotations)	KLF12 ACAP1 CD247 AKNA ZAP70	1.36e-05	191	71	5	0646cca78e24aeb6baa9934d3c439b797c567997
ToppCell	COVID-19-T_cells\|COVID-19 / group, cell type (main and fine annotations)	KLF12 ACAP1 CD247 AKNA ZAP70	1.36e-05	191	71	5	7f64add931b64b8d35836fa6bee9ebab593844d3
ToppCell	COVID-19-lung-CD4+_Treg\|lung / Disease (COVID-19 only), tissue and cell type	KLF12 ACAP1 CD247 AKNA ZAP70	1.36e-05	191	71	5	73ea3078c1f55cd47e4d99e77b3ce4ff17549d49
ToppCell	COPD-Lymphoid-T_Cytotoxic\|World / Disease state, Lineage and Cell class	KLF12 ACAP1 CD247 AKNA ZAP70	1.39e-05	192	71	5	5bfd9f5d47511441eb2d3cc3c4d7ed330ffd0bd1
ToppCell	T/NK_cells-CD56bright_NK_cell\|World / Lineage and Cell class	ACAP1 CD247 ZBTB16 DRAP1 ZAP70	1.39e-05	192	71	5	528b5b790a0e8966d04ffbc83b049c93bac17537
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD247 ZBTB16 AKNA COL5A3 ZAP70	1.39e-05	192	71	5	ce867b6e78c1d8f30dff81bf572a78a897bc7625
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD247 ZBTB16 AKNA COL5A3 ZAP70	1.39e-05	192	71	5	58a7829b411b02b422ef75e2277a868969cc23e8
ToppCell	COPD-Lymphoid\|COPD / Disease state, Lineage and Cell class	KLF12 ACAP1 CD247 AKNA ZAP70	1.39e-05	192	71	5	064fefb8212fadab0ff441f4bf643559b7fdb25d
ToppCell	Immune-natural_killer_cell\|World / Lineage, Cell type, age group and donor	KLF12 ACAP1 CD247 AKNA ZAP70	1.39e-05	192	71	5	68121a6ef4115a93d87aad8802ef9b27d793d8c0
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ACAP1 CD247 AKNA ATG2A ZAP70	1.39e-05	192	71	5	ed1fb700d3e8f00495727d61e164fc0b70274fd0
ToppCell	NS-moderate-d_07-13-Lymphoid\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KLF12 ACAP1 CD247 AKNA ZAP70	1.39e-05	192	71	5	bd4059bfc2159f5ed8bbb2a5408b56117ca6f8e1
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ACAP1 CD247 AKNA ATG2A ZAP70	1.39e-05	192	71	5	6779b0294bb058e748e22b795b6a381c4add37e9
ToppCell	COPD-Lymphoid-T_Cytotoxic\|COPD / Disease state, Lineage and Cell class	KLF12 ACAP1 CD247 AKNA ZAP70	1.43e-05	193	71	5	58e94fe2e89cdafc6974938f97a4c162061a437d
ToppCell	IPF-Lymphoid\|IPF / Disease state, Lineage and Cell class	KLF12 ACAP1 CD247 AKNA ZAP70	1.43e-05	193	71	5	bf9d50aea909a28dd1d0933af33842d5f1ae7818
ToppCell	Adult-Immune-T_lymphocyte\|Adult / Lineage, Cell type, age group and donor	KLF12 ACAP1 CD247 AKNA ZAP70	1.43e-05	193	71	5	26df0c4c8a2355dd5503fadd07e368eb9a2bf06a
ToppCell	COVID-19-lung-CD8+_T_cells\|lung / Disease (COVID-19 only), tissue and cell type	KLF12 ACAP1 CD247 AKNA ZAP70	1.43e-05	193	71	5	780e23e2705fc5c1b70e37568b79731ced5038bd
ToppCell	IPF-Lymphoid-T_Cytotoxic\|World / Disease state, Lineage and Cell class	KLF12 ACAP1 CD247 AKNA ZAP70	1.43e-05	193	71	5	35c902a983d7f1156a74fe68ee366609029833b3
ToppCell	3'_v3-bone_marrow-Lymphocytic_NK\|bone_marrow / Manually curated celltypes from each tissue	CD247 ZBTB16 AKNA ZAP70 RBM39	1.43e-05	193	71	5	e790ab76c12f74a13936c231076f1e397283efb3
ToppCell	3'_v3-Lung-Lymphocytic_NK\|Lung / Manually curated celltypes from each tissue	CD247 ZBTB16 AKNA ZAP70 RBM39	1.43e-05	193	71	5	a98ee519e0da93ae4a2dcdda1ee8b4138dec131b
ToppCell	COVID-19-kidney-T-cells-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KLF12 ACAP1 CD247 AKNA ZAP70	1.43e-05	193	71	5	5b84fa640cf30dea55fde53b810f850ff946d253
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACAP1 CD247 AKNA ATG2A ZAP70	1.43e-05	193	71	5	db9378c5bb5c27b321957a05dcabf40e97a3b725
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KLF12 ACAP1 CD247 AKNA ZAP70	1.43e-05	193	71	5	1cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCell	COVID-CD8-CD8_1\|COVID / Condition, Cell_class and T cell subcluster	ACAP1 CD247 AKNA ZNF80 ZAP70	1.43e-05	193	71	5	221690901cb214c8ee186ff527c80dcc52d1fb1c
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KLF12 ACAP1 CD247 AKNA ZAP70	1.43e-05	193	71	5	b9769b45125d2244afe53f9f71c92c04ddccf980
ToppCell	COVID-19-lung-NK/NKT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KLF12 ACAP1 CD247 AKNA ZAP70	1.43e-05	193	71	5	c24b44fcc92fff42ebba6f1aff91c7aaea179e56
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-CD8_Tmem\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACAP1 CD247 AKNA ZNF80 ZAP70	1.43e-05	193	71	5	30db4ddfdeb225cc934cf52af1fbcccfdaeb6223
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-Activated_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACAP1 CD247 ZBTB16 AKNA ZAP70	1.46e-05	194	71	5	e3705346755cbf65fc276d4d4fbee936ed6bb7bf
Disease	schizophrenia, gastroesophageal reflux disease	SATB2 TSNARE1	2.92e-04	11	69	2	EFO_0003948, MONDO_0005090
Disease	skin sensitivity to sun	KATNAL1 HERC2	8.98e-04	19	69	2	EFO_0004795
Disease	Severe Combined Immunodeficiency	CD247 ZAP70	9.96e-04	20	69	2	C0085110
Disease	platelet-to-lymphocyte ratio	KLF12 ZBTB16 KMT5A COX4I2 NUP160	1.62e-03	363	69	5	EFO_0008446
Disease	NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE	COL4A3 NUP160	2.25e-03	30	69	2	C1868672

Protein segments in the cluster

Peptide	Gene	Start	Entry
RSVDGGLMVKGPRHK	AFDN	511	P55196
RGGPGKMDKGEHRQE	EWSR1	636	Q01844
HMPGGDGHRGKSLKL	SLC4A3	491	P48751
PRGPKGHMGERVIGH	COL4A3	211	Q01955
GGGGIGHQKRKPDIM	ETV3	216	P41162
GDPGEEGKHGKVGRM	COLEC10	56	Q9Y6Z7
EGPGGLVMEGHLFKR	ACAP1	261	Q15027
RGAELRVPGGAKHGM	ARL16	11	Q0P5N6
RVPGGAKHGMCLLLG	ARL16	16	Q0P5N6
MLRRRGSPGMGVHVG	CD276	1	Q5ZPR3
RGASGRKGQGRGPHM	ATG2A	1031	Q2TAZ0
HMDGDKGARRGRKPG	DRAP1	101	Q14919
KKAIMHGRGRGVAGP	RBM33	1061	Q96EV2
LNGFELAGRPMKVGH	RBM39	311	Q14498
RVIPGGVADRHGGLK	LIN7B	121	Q9HAP6
RARCHGPGRAAGGKM	KMT5A	36	Q9NQR1
MPKGGRKGGHKGRAR	PDAP1	1	Q13442
GGIDGRLRLGGQVMH	HERC2	2211	O95714
VRGPDGRMHGNKCAL	SPINK5	246	Q9NQ38
HAGKDGTMPRAGRSL	KIF26B	1696	Q2KJY2
MGLKARRAAGAAGGG	KCNQ3	1	O43525
GSGIERMGPLGLDHM	HNRNPM	451	P52272
KGGHLRSMESNGRPA	BSN	3301	Q9UPA5
RHGARVEKYGPGPMG	BSN	3326	Q9UPA5
FHGRSPIGGMAGVKR	MICALL2	106	Q8IY33
GGAARMLRTPGRHGY	PEX7	6	O00628
MPGISARGLSHEGRK	METTL25B	1	Q96FB5
DHMGGIPARNSKGER	PIP5K1A	381	Q99755
GGRLGAPMERHGRAS	PANK2	126	Q9BZ23
AGPFLKREGHRSGEM	FCHSD1	61	Q86WN1
PRRGHKSGGAMAAGD	FZD5	541	Q13467
RQAMGHRHKAGGAGR	APC2	1436	O95996
RHGVMLVGPTGGGKT	DNAH6	1746	Q9C0G6
IGMKGERRRGKGHDG	CD247	126	P20963
GRHPGHLKGREIGMW	DHX36	51	Q9H2U1
RDGHMSGLGKAEAAP	AKNA	851	Q7Z591
EGRGGRRGHDAPMIA	ADPRHL1	266	Q8NDY3
GSKPLISMRGHEDGG	BTN2A1	146	Q7KYR7
RRGMHQKGGIPNVEG	GNL3	371	Q9BVP2
EDGRGHGKAQMDPRG	KLF12	216	Q9Y4X4
PGMRGHKGAKGEIGE	COL9A1	426	P20849
PKLMQLVDHRGGGGG	DDX17	546	Q92841
VMGPREARGAALGGV	FCRLB	201	Q6BAA4
KRGPSGHMGREGREG	COL5A3	1311	P25940
LRKGGGGRRGMHSSE	COX4I2	11	Q96KJ9
MAERGRKRPCGPGEH	SPOUT1	1	Q5T280
EMAGVGARGPVGRAH	KATNAL1	126	Q9BW62
RERGPQGQGHGRMAL	NCKAP5	561	O14513
MGHDGSTGKNLREPG	HEPH	396	Q9BQS7
MGARGRPNGAVAKAV	SATB2	41	Q9UPW6
GARKVVEELGGHMPR	MUTYH	186	Q9UIF7
RGAMGSAGAHPGDKL	OLIG2	56	Q13516
RLRRGGDPGLMHGKT	RDH14	31	Q9HBH5
VGRRGDGGKMAAAGA	NUP160	26	Q12769
GRPGKRIVGTMQGGD	CLUAP1	346	Q96AJ1
LPGMKGHRGFSGLDG	COL1A1	261	P02452
VKGLGPGRLSAMHGL	MRPS11	151	P82912
MAGGGPLHKFLVGKR	ZAP70	416	P43403
SGDLRPMGIALGGHR	USP21	116	Q9UK80
PRKDSAAGPHGRMAG	TSNARE1	101	Q96NA8
GGGRHPGVAEVKTEM	ZBTB16	231	Q05516
KEGIGRVIGMGVPHS	SLC25A46	241	Q96AG3
GVAGEGVRRKGEMGL	TRIM15	366	Q9C019
PKRDGRSMGEGGKPH	SOX10	256	P56693
PVKMRKSGGRDHTGR	MRPL2	76	Q5T653
KGRRDGLPAHIGSMA	MYO18B	626	Q8IUG5
AGGPRKGYMGHLTRV	PPP6R1	456	Q9UPN7
AGMRGLGKAPHSGEG	nan	76	Q8IYB0
MSPKRDGLGTGDGLH	ZNF80	1	P51504
PGMVGLHGRRNSGKL	ZSWIM6	1116	Q9HCJ5
EGMIRKRSGGHRVPG	PLD2	206	O14939
CPMKGRGLVGAAHTR	TULP3	286	O75386
HGGVLARKMSLGGGR	ULK1	486	O75385
GAGRLMGPKGVAVDR	TRIM3	571	O75382