Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsingle-stranded DNA binding

SSBP2 SSBP4

1.22e-0313482GO:0003697
GeneOntologyBiologicalProcessmembrane organization

ANO4 RTP1 KIAA0319L

2.65e-0391473GO:0061024
DomainSSDP_DNA-bd

SSBP2 SSBP4

4.82e-07382IPR008116
DomainLisH

SSBP2 SSBP4

6.03e-052882SM00667
DomainLisH

SSBP2 SSBP4

6.03e-052882IPR006594
DomainLISH

SSBP2 SSBP4

6.03e-052882PS50896
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ANO4 ATP13A4

9.15e-0417642MM15718
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ANO4 ATP13A4

9.89e-0418342M997
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ANO4 ATP13A4

1.31e-0268142MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ANO4 ATP13A4

1.52e-0273642M27287
Pubmed

A novel, evolutionarily conserved gene family with putative sequence-specific single-stranded DNA-binding activity.

SSBP2 SSBP4

1.39e-0738212079286
Pubmed

Single-stranded DNA binding proteins are required for LIM complexes to induce transcriptionally active chromatin and specify spinal neuronal identities.

SSBP2 SSBP4

2.54e-06118226965372
Pubmed

TIF1gamma controls erythroid cell fate by regulating transcription elongation.

SSBP2 SSBP4

7.07e-06188220603019
Pubmed

Control of developmentally primed erythroid genes by combinatorial co-repressor actions.

SSBP2 SSBP4

2.01e-05308226593974
InteractionIDI2 interactions

SSBP2 SSBP4

1.25e-051482int:IDI2
InteractionSLF1 interactions

SSBP2 SSBP4

4.46e-052682int:SLF1
InteractionPYGO1 interactions

SSBP2 SSBP4

5.19e-052882int:PYGO1
InteractionLMX1B interactions

SSBP2 SSBP4

8.15e-053582int:LMX1B
InteractionISL1 interactions

SSBP2 SSBP4

1.12e-044182int:ISL1
InteractionISL2 interactions

SSBP2 SSBP4

1.12e-044182int:ISL2
InteractionIL36RN interactions

SSBP2 SSBP4

1.35e-044582int:IL36RN
InteractionBCL9L interactions

SSBP2 SSBP4

1.54e-044882int:BCL9L
InteractionLHX8 interactions

SSBP2 SSBP4

1.88e-045382int:LHX8
InteractionLDB2 interactions

SSBP2 SSBP4

2.10e-045682int:LDB2
InteractionLHX6 interactions

SSBP2 SSBP4

2.25e-045882int:LHX6
InteractionSSBP4 interactions

SSBP2 SSBP4

2.33e-045982int:SSBP4
InteractionCBFA2T3 interactions

SSBP2 SSBP4

4.08e-047882int:CBFA2T3
InteractionBCL9 interactions

SSBP2 SSBP4

4.96e-048682int:BCL9
InteractionLHX1 interactions

SSBP2 SSBP4

7.10e-0410382int:LHX1
InteractionSSBP2 interactions

SSBP2 SSBP4

7.38e-0410582int:SSBP2
InteractionLDB1 interactions

SSBP2 SSBP4

8.84e-0411582int:LDB1
InteractionSSBP3 interactions

SSBP2 SSBP4

9.46e-0411982int:SSBP3
InteractionHLA-DRB1 interactions

SSBP2 KIAA0319L

1.01e-0312382int:HLA-DRB1
InteractionMFAP4 interactions

SSBP2 SSBP4

1.29e-0313982int:MFAP4
InteractionLMO3 interactions

SSBP2 SSBP4

1.54e-0315282int:LMO3
InteractionLMO1 interactions

SSBP2 SSBP4

1.58e-0315482int:LMO1
InteractionLMO4 interactions

SSBP2 SSBP4

1.68e-0315982int:LMO4
InteractionLHX4 interactions

SSBP2 SSBP4

1.83e-0316682int:LHX4
InteractionPREB interactions

ANO4 SSBP4

2.05e-0317682int:PREB
InteractionLHX2 interactions

SSBP2 SSBP4

2.22e-0318382int:LHX2
InteractionLHX3 interactions

SSBP2 SSBP4

2.26e-0318582int:LHX3
InteractionSPG21 interactions

DHX40 SSBP4

2.61e-0319982int:SPG21
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Sparc_(Sparc)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RTP1 ATP13A4

4.87e-05608266542df5eb7080a879b02c306a7ccbd9f67bf54d
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Sparc_(Sparc)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RTP1 ATP13A4

4.87e-056082f54674b9995680c7f201cf1142e7f9327960f42f
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Sparc_(Sparc)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RTP1 ATP13A4

4.87e-056082746a1ac6e666d1d53a4bea8f103642f2fa42e725
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Htra1)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RTP1 ATP13A4

1.00e-048682c1181a7e9f4cbde5a3bee7b54d6448dfce58b238
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Htra1)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RTP1 ATP13A4

1.00e-048682c6c0e8e562ffc705e0cd3f503a9e43ca2669e9b0
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Htra1)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RTP1 ATP13A4

1.00e-0486824263673abf183f2e04f1a2bf37e365a25b8cb0b4
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RTP1 ATP13A4

1.70e-0411282e30cd0b7b755c63081bbeed4e1a884b6640d34f8
ToppCellPosterior_cortex-Macroglia-ASTROCYTE|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RTP1 ATP13A4

1.70e-04112821c0bcc6c972c50a9d950cd56b65efb8d778ec25a
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

RTP1 ATP13A4

1.99e-0412182a33e4ae0b0efb702db1b646ac0486e3b6ce48457
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)|Hippocampus / BrainAtlas - Mouse McCarroll V32

RTP1 ATP13A4

1.99e-04121828334a6b2ced1d6a4808458d6d4232d1b688ba28a
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)--|Hippocampus / BrainAtlas - Mouse McCarroll V32

RTP1 ATP13A4

1.99e-04121824b33eeed7b70da120133b14d42c104d2461d52dc
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 ATP13A4

2.51e-0413682a2063abe2d7c3277bfbe1514c8c66363cf04b248
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 ATP13A4

2.55e-04137828e2fa2ef8becace96a68bb85c002329110902fbb
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGMS2 ATP13A4

3.17e-0415382e7a074ea8232bacf924be78a244a8507c7e1ebc8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SSBP4 ATP13A4

3.51e-0416182bf4bfb416cb6ef43fc8cf0ffc2d7f0b6b42ab4da
ToppCellControl|World / group, cell type (main and fine annotations)

SGMS2 ATP13A4

3.82e-0416882a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellAT1-AT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

RTP1 ATP13A4

4.15e-0417582bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SSBP2 ATP13A4

4.29e-0417882fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

SSBP2 ATP13A4

4.34e-0417982d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGMS2 ATP13A4

4.34e-041798204ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

SGMS2 ATP13A4

4.44e-0418182c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGMS2 ATP13A4

4.63e-04185823bef59cc0aa939d2a7e52f0f6c61bc00528fe50b
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1-AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGMS2 ATP13A4

4.63e-041858268f428e169cfb77de970bdfdeea9b9f16f68d2ba
ToppCellLPS_only-Epithelial_alveolar|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGMS2 ATP13A4

4.68e-0418682e0a2ea4b46af742bc7c9b2072bb85e27d5c92712
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGMS2 ATP13A4

4.68e-04186824e94158db52df41d71e67b02b9895a358eebee0f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ANO4 SSBP2

4.73e-041878213731298bc562ec29582f5da1b4c97261284f6f1
ToppCellLPS_only-Epithelial_alveolar-AT_1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGMS2 ATP13A4

4.73e-0418782ff26a533d310126521efe1d05cf8b9d32e524550
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

SGMS2 ATP13A4

4.78e-0418882707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

4.78e-04188820d86044bc340e3efb90d0022dd299873639d831c
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

4.78e-0418882beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

4.94e-041918260ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

4.99e-0419282b73f24d1c55dfef1eb01c26da117dbf637ea080a
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIAA0319L ATP13A4

4.99e-041928229f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

4.99e-0419282450baeb5c3df7a9445472530002ce38f177a333c
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

5.04e-0419382b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

5.04e-0419382b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SGMS2 ATP13A4

5.09e-0419482db06ae2dba45640da329a4d0d94973ac9dda7729
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

5.09e-04194826b286992d4bb56013c0ea5a7601d3476d806175a
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

5.09e-0419482f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SGMS2 ATP13A4

5.09e-0419482d3f5cd6c40354bfe86348bb0e82697a939759625
ToppCellPCW_13-14-Epithelial-Epithelial_airway|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

5.09e-04194827b2b40a56eb9c7203ca50133b2da4fd8fdd4a5cf
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SGMS2 ATP13A4

5.09e-0419482d4f4036b650a27312283fa8851f3975595cc2d3f
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

5.09e-0419482c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCellControl-Classical_Monocyte|Control / Disease condition and Cell class

SGMS2 KIAA0319L

5.09e-04194829e33e1b54b4114f9e6981819834bb796ed7192b5
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-epithelial_cell_of_lung|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SGMS2 ATP13A4

5.09e-04194824974c208e6ee37a51cd95a61d48b26c5de416992
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

5.14e-0419582d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCellPCW_10-12-Epithelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

5.20e-04196829bfb31ff3e4f2c0a9405c418c86bfec5dbca23e2
ToppCellcontrol-immature_Neutrophil|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DHX40 KIAA0319L

5.20e-0419682e34fd3e7a5b1c22a81fd3208e6d58bdb846d51c4
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SSBP2 ATP13A4

5.30e-04198821408e02e053ad3406229bfe8189da03be6366e81
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SGMS2 ATP13A4

5.30e-04198826ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SSBP2 ATP13A4

5.30e-0419882af399569c718f5fd971d73a7926768c9311002a3
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ANO4 SGMS2

5.30e-04198826a539d3b47bd2d4a7ad5c67cad23facffc0ac45f
ToppCellPCW_13-14-Epithelial|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

5.30e-041988248eb6f69a464a34ab32e8d425a22b9d45ec20428
ToppCellPCW_10-12-Epithelial-Epithelial_airway|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SGMS2 ATP13A4

5.30e-04198829a12e5e47236433e512c668005fe3f8be6fde95c
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SGMS2 ATP13A4

5.36e-0419982d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellproximal-Epithelial-Club|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SGMS2 ATP13A4

5.36e-041998299d23c0373f1ae5267bb3e51c5c88c8f52559ae4
ToppCellproximal-Epithelial-Club-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SGMS2 ATP13A4

5.36e-0419982e8b3b003b581aa001c23440a03d80da9560129b3
ToppCellproximal-3-Epithelial-Club|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SGMS2 ATP13A4

5.36e-041998277dc850032746339557c844cfc1f93eb27210f22
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SGMS2 ATP13A4

5.41e-04200828683445ad5b70748c4a1f12eb77d47623085147e
Diseasesoluble triggering receptor expressed on myeloid cells 2 measurement

SSBP2 ATP13A4

2.70e-0329682EFO_0010151

Protein segments in the cluster

PeptideGeneStartEntry
YWRPAWHVWAHCVPC

ATP13A4

51

Q4VNC1
HRHLLYECWASWGVW

ANO4

316

Q32M45
WAACCQDSACHVFWW

KIAA0319L

86

Q8IZA0
SWCQKHWIHWRCLFS

DHX40

571

Q8IX18
RFHCSWCWHTWQSPY

RTP1

91

P59025
LHSWWCVFWDLYCAA

SSBP2

61

P81877
RHFWWYHLICWLLSA

SGMS2

246

Q8NHU3
HSWWCVFWDLYCAAP

SSBP4

61

Q9BWG4