Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscell-cell adhesion mediated by cadherin

CDH20 CDHR2 CDH5 CDH11 CDH12

9.68e-0750745GO:0044331
GeneOntologyBiologicalProcesscalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

CDH20 CDH5 CDH11 CDH12

3.91e-0553744GO:0016339
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

FAT4 CDH20 CDHR2 CDH5 CDH11 CDH12

5.69e-05187746GO:0007156
GeneOntologyBiologicalProcessadherens junction organization

CDH20 CDH5 CDH11 CDH12

6.82e-0561744GO:0034332
GeneOntologyCellularComponentcatenin complex

CDH20 CDH5 CDH11 CDH12

4.57e-0632734GO:0016342
DomainCadherin_cytoplasmic-dom

CDH20 CDH5 CDH11 CDH12

2.42e-0625724IPR000233
DomainCadherin_C

CDH20 CDH5 CDH11 CDH12

2.42e-0625724PF01049
DomainCadherin_CS

FAT4 CDH20 CDHR2 CDH5 CDH11 CDH12

3.93e-06109726IPR020894
DomainCatenin_binding_dom

CDH20 CDH5 CDH11 CDH12

4.48e-0629724IPR027397
Domain-

CDH20 CDH5 CDH11 CDH12

4.48e-06297244.10.900.10
DomainCADHERIN_1

FAT4 CDH20 CDHR2 CDH5 CDH11 CDH12

4.84e-06113726PS00232
DomainCadherin

FAT4 CDH20 CDHR2 CDH5 CDH11 CDH12

4.84e-06113726PF00028
DomainCADHERIN_2

FAT4 CDH20 CDHR2 CDH5 CDH11 CDH12

5.10e-06114726PS50268
Domain-

FAT4 CDH20 CDHR2 CDH5 CDH11 CDH12

5.10e-061147262.60.40.60
DomainCA

FAT4 CDH20 CDHR2 CDH5 CDH11 CDH12

5.36e-06115726SM00112
DomainCadherin-like

FAT4 CDH20 CDHR2 CDH5 CDH11 CDH12

5.64e-06116726IPR015919
DomainCadherin

FAT4 CDH20 CDHR2 CDH5 CDH11 CDH12

6.22e-06118726IPR002126
DomainARM-type_fold

MON2 SF3B1 PSME4 UPF2 PIK3C3 USP9X RRP12 APOB

4.73e-05339728IPR016024
Domain-

MON2 SF3B1 PSME4 USP9X RRP12

1.66e-032227251.25.10.10
DomainARM-like

MON2 SF3B1 PSME4 USP9X RRP12

3.87e-03270725IPR011989
DomainP-loop_NTPase

MAGI1 ABCA6 NAV3 SRL MYO1B CHD1 AK7 NLRC4 DDX5

5.15e-03848729IPR027417
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

MAGI1 CDK17 KMT2C SF3B1 TSR1 PIK3C3 CLK3 USP9X SF3A1 RRP12 EIF3L MYO1B CHD1 TNFAIP8 DDX5

7.02e-081284741517353931
Pubmed

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.

SF3B1 POLR1A TSR1 USP9X SF3A1 RRP12 CHD1 DDX5

2.57e-0730074828561026
Pubmed

Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.

RELN MTX2 PITRM1 SF3A1 SRL ACAD10 PCCB TXNDC12

5.40e-0733174829199018
Pubmed

Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue.

CDH5 CDH11 CDH12

1.10e-06107432059658
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TMEM201 SF3B1 POLR1A PITRM1 TSR1 USP9X SF3A1 RRP12 EIF3L PPA2 MYO1B CHD1 APOB DDX5

1.61e-061425741430948266
Pubmed

Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy.

CDH20 CDH11 CDH12

2.01e-061274322102170
Pubmed

Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity.

CDH5 CDH11 CDH12

2.60e-06137439615235
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

HIPK3 POLR1A EGFR CLK3 SF3A1 EIF3L MLLT1 MYO1B CHD1 ACAD10 CBL

3.45e-06910741136736316
Pubmed

Differential Spatiotemporal Expression of Type I and Type II Cadherins Associated With the Segmentation of the Central Nervous System and Formation of Brain Nuclei in the Developing Mouse.

CDH20 CDH11 CDH12

4.13e-061574333833667
Pubmed

Knockout of c-Cbl slows EGFR endocytic trafficking and enhances EGFR signaling despite incompletely blocking receptor ubiquitylation.

EGFR CBL

4.47e-06274233811466
Pubmed

Termination of tyrphostin AG1478 application results in different recovery of EGF receptor tyrosine residues 1045 and 1173 phosphorylation in A431 cells.

EGFR CBL

4.47e-06274219947936
Pubmed

Induction of Cbl-dependent epidermal growth factor receptor degradation in Ling Zhi-8 suppressed lung cancer.

EGFR CBL

4.47e-06274228198003
Pubmed

Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition.

EGFR CBL

4.47e-06274225348515
Pubmed

The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor.

EGFR CBL

4.47e-06274210428778
Pubmed

Visualizing late states of human 40S ribosomal subunit maturation.

TSR1 RRP12

4.47e-06274229875412
Pubmed

HPV16 E5 protein disrupts the c-Cbl-EGFR interaction and EGFR ubiquitination in human foreskin keratinocytes.

EGFR CBL

4.47e-06274215735736
Pubmed

Coding sequence, exon-intron structure and chromosomal localization of murine TNF-stimulated gene 6 that is specifically expressed by expanding cumulus cell-oocyte complexes.

TNFAIP6 NEB

4.47e-0627429427551
Pubmed

Epidermal Growth Factor Receptor Mutation Enhances Expression of Cadherin-5 in Lung Cancer Cells.

EGFR CDH5

4.47e-06274227362942
Pubmed

Molecular mechanisms of cigarette smoke-induced proliferation of lung cells and prevention by vitamin C.

EGFR CBL

4.47e-06274221772844
Pubmed

Impaired degradation followed by enhanced recycling of epidermal growth factor receptor caused by hypo-phosphorylation of tyrosine 1045 in RBE cells.

EGFR CBL

4.47e-06274222591401
Pubmed

A novel dileucine lysosomal-sorting-signal mediates intracellular EGF-receptor retention independently of protein ubiquitylation.

EGFR CBL

4.47e-06274216105874
Pubmed

Hypophosphorylation of residue Y1045 leads to defective downregulation of EGFRvIII.

EGFR CBL

4.47e-06274216969069
Pubmed

Identification of Predictive ERBB Mutations by Leveraging Publicly Available Cell Line Databases.

EGFR CBL

4.47e-06274233323455
Pubmed

Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis.

EGFR CBL

4.47e-06274212754251
Pubmed

Peritumoral Cbl is a strong independent prognostic marker after curative resection of hepatocellular carcinoma.

EGFR CBL

4.47e-06274226474280
Pubmed

Proximity interactome of lymphatic VE-cadherin reveals mechanisms of junctional remodeling and reelin secretion.

RELN CDH5

4.47e-06274239232006
Pubmed

RASopathy-associated CBL germline mutations cause aberrant ubiquitylation and trafficking of EGFR.

EGFR CBL

4.47e-06274225178484
Pubmed

(-)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells.

EGFR CBL

4.47e-06274219578043
Pubmed

Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development.

EGFR CBL

4.47e-0627429121472
Pubmed

Peptide truncation leads to a twist and an unusual increase in affinity for casitas B-lineage lymphoma tyrosine kinase binding domain.

EGFR CBL

4.47e-06274222394513
Pubmed

Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry.

MTX2 PITRM1 GLDC PPA2 ACAD10 PCCB TXNDC12

8.72e-0634374728130547
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

SF3B1 POLR1A TSR1 USP9X SF3A1 RRP12 EIF3L MYO1B CHD1

1.02e-0565374922586326
Pubmed

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.

CDH5 CDH11 CDH12

1.03e-05207437806582
Pubmed

Src promotes destruction of c-Cbl: implications for oncogenic synergy between Src and growth factor receptors.

EGFR CBL

1.34e-05374212604776
Pubmed

Methods to Investigate EGFR Ubiquitination.

EGFR CBL

1.34e-05374228791635
Pubmed

Intersectin regulates epidermal growth factor receptor endocytosis, ubiquitylation, and signaling.

EGFR CBL

1.34e-05374216914641
Pubmed

A novel role of Sprouty 2 in regulating cellular apoptosis.

EGFR CBL

1.34e-05374218070883
Pubmed

Cortactin promotes colorectal cancer cell proliferation by activating the EGFR-MAPK pathway.

EGFR CBL

1.34e-05374227903975
Pubmed

Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling.

EGFR CBL

1.34e-05374217486068
Pubmed

microRNA-155-5p initiates childhood acute lymphoblastic leukemia by regulating the IRF4/CDK6/CBL axis.

IRF4 CBL

1.34e-05374234775495
Pubmed

The 14-3-3σ protein promotes HCC anoikis resistance by inhibiting EGFR degradation and thereby activating the EGFR-dependent ERK1/2 signaling pathway.

EGFR CBL

1.34e-05374233391517
Pubmed

Cell surface epidermal growth factor receptors increase Src and c-Cbl activity and receptor ubiquitylation.

EGFR CBL

1.34e-05374225074934
Pubmed

ERbeta1 represses basal breast cancer epithelial to mesenchymal transition by destabilizing EGFR.

EGFR CBL

1.34e-05374223158001
Pubmed

Metastasis suppressor tetraspanin CD82/KAI1 regulates ubiquitylation of epidermal growth factor receptor.

EGFR CBL

1.34e-05374223897813
Pubmed

Systematic identification of CDC34 that functions to stabilize EGFR and promote lung carcinogenesis.

EGFR CBL

1.34e-05374232114396
Pubmed

[Expressions of c-Cbl, Cbl-b and EGFR and its role of prognosis in NSCLC].

EGFR CBL

1.34e-05374221645455
Pubmed

Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis.

EGFR CBL

1.34e-05374215635092
Pubmed

Vinexin beta regulates the phosphorylation of epidermal growth factor receptor on the cell surface.

EGFR CBL

1.34e-05374216923119
Pubmed

Serine mutations that abrogate ligand-induced ubiquitination and internalization of the EGF receptor do not affect c-Cbl association with the receptor.

EGFR CBL

1.34e-05374214627991
Pubmed

CTEN prolongs signaling by EGFR through reducing its ligand-induced degradation.

EGFR CBL

1.34e-05374223774213
Pubmed

Additional serine/threonine phosphorylation reduces binding affinity but preserves interface topography of substrate proteins to the c-Cbl TKB domain.

EGFR CBL

1.34e-05374220877636
Pubmed

LIF-dependent JAK3 activation is not essential for retinal degeneration.

LIF RPE65

1.34e-05374220345762
Pubmed

USP9X Controls EGFR Fate by Deubiquitinating the Endocytic Adaptor Eps15.

EGFR USP9X

1.34e-05374226748853
Pubmed

SERPINE2 promotes liver cancer metastasis by inhibiting c-Cbl-mediated EGFR ubiquitination and degradation.

EGFR CBL

1.34e-05374238407942
Pubmed

Nuclear trafficking of EGFR by Vps34 represses Arf expression to promote lung tumor cell survival.

EGFR PIK3C3

1.34e-05374226686095
Pubmed

SH2-containing 5'-inositol phosphatase, SHIP2, regulates cytoskeleton organization and ligand-dependent down-regulation of the epidermal growth factor receptor.

EGFR CBL

1.34e-05374215668240
Pubmed

Erbin interacts with c-Cbl and promotes tumourigenesis and tumour growth in colorectal cancer by preventing c-Cbl-mediated ubiquitination and down-regulation of EGFR.

EGFR CBL

1.34e-05374225521828
Pubmed

Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells.

EGFR DUSP6

1.34e-05374230475204
Pubmed

Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation.

EGFR CBL

1.34e-05374215475003
Pubmed

Transient receptor potential type vanilloid 1 suppresses skin carcinogenesis.

EGFR CBL

1.34e-05374219155296
Pubmed

c-Cbl directs EGF receptors into an endocytic pathway that involves the ubiquitin-interacting motif of Eps15.

EGFR CBL

1.34e-05374215383614
Pubmed

δ-Catenin Increases the Stability of EGFR by Decreasing c-Cbl Interaction and Enhances EGFR/Erk1/2 Signaling in Prostate Cancer.

EGFR CBL

1.34e-05374229629558
Pubmed

Epidermal growth factor receptor exposed to cigarette smoke is aberrantly activated and undergoes perinuclear trafficking.

EGFR CBL

1.34e-05374217971399
Pubmed

Loss of function Cbl-c mutations in solid tumors.

EGFR CBL

1.34e-05374231260484
Pubmed

EGF and amphiregulin differentially regulate Cbl recruitment to endosomes and EGF receptor fate.

EGFR CBL

1.34e-05374218045238
Pubmed

G protein pathway suppressor 2 suppresses gastric cancer by destabilizing epidermal growth factor receptor.

EGFR CBL

1.34e-05374234609770
Pubmed

The Cbl RING finger C-terminal flank controls epidermal growth factor receptor fate downstream of receptor ubiquitination.

EGFR CBL

1.34e-05374216246327
Pubmed

A ligand-inducible anaplastic lymphoma kinase chimera is endocytosis impaired.

EGFR CBL

1.34e-05374214691459
Pubmed

EGFRvIII escapes down-regulation due to impaired internalization and sorting to lysosomes.

EGFR CBL

1.34e-05374217372273
Pubmed

Neural cell adhesion molecule-180-mediated homophilic binding induces epidermal growth factor receptor (EGFR) down-regulation and uncouples the inhibitory function of EGFR in neurite outgrowth.

EGFR CBL

1.34e-05374217995934
Pubmed

The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.

EGFR CBL

1.34e-05374221949687
Pubmed

Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression.

EGFR NAV3

1.34e-05374225678558
Pubmed

The hominoid-specific oncogene TBC1D3 activates Ras and modulates epidermal growth factor receptor signaling and trafficking.

EGFR CBL

1.34e-05374218319245
Pubmed

The ShcD phosphotyrosine adaptor subverts canonical EGF receptor trafficking.

EGFR CBL

1.34e-05374228724758
Pubmed

Expression of c-Cbl, Cbl-b, and epidermal growth factor receptor in gastric carcinoma and their clinical significance.

EGFR CBL

1.34e-05374220038312
Pubmed

Berberine inhibits proliferation and down-regulates epidermal growth factor receptor through activation of Cbl in colon tumor cells.

EGFR CBL

1.34e-05374223457600
Pubmed

Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration.

EGFR CBL

1.34e-05374220940296
Pubmed

Inhibition of PLK1 Destabilizes EGFR and Sensitizes EGFR-Mutated Lung Cancer Cells to Small Molecule Inhibitor Osimertinib.

EGFR CBL

1.34e-05374237174055
Pubmed

Uncommon somatic mutations in metastatic NUT midline carcinoma.

KMT2C SF3B1

1.34e-05374228967088
Pubmed

SGCE Promotes Breast Cancer Stem Cells by Stabilizing EGFR.

EGFR CBL

1.34e-05374232714745
Pubmed

Coupling of the proto-oncogene product c-Cbl to the epidermal growth factor receptor.

EGFR CBL

1.34e-0537427592693
Pubmed

c-Cbl-mediated ubiquitinylation is required for epidermal growth factor receptor exit from the early endosomes.

EGFR CBL

1.34e-05374215210722
Pubmed

Cbl competitively inhibits epidermal growth factor-induced activation of phospholipase C-gamma1.

EGFR CBL

1.34e-05374212803489
Pubmed

PLEK2 promotes gallbladder cancer invasion and metastasis through EGFR/CCL2 pathway.

EGFR CBL

1.34e-05374231182136
Pubmed

Long Noncoding RNA LINC01485 Promotes Tumor Growth and Migration via Inhibiting EGFR Ubiquitination and Activating EGFR/Akt Signaling in Gastric Cancer.

EGFR CBL

1.34e-05374232904620
Pubmed

Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment.

EGFR CBL

1.34e-05374215465819
Pubmed

Cbl and Cbl-b independently regulate EGFR through distinct receptor interaction modes.

EGFR CBL

1.34e-05374237903221
Pubmed

Light stress affects cones and horizontal cells via rhodopsin-mediated mechanisms.

LIF RPE65

1.34e-05374231291592
Pubmed

A tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulation.

EGFR CBL

1.34e-05374218316398
Pubmed

αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor.

EGFR CBL

1.34e-05374226177020
Pubmed

Weak binding to E3 ubiquitin ligase c-Cbl increases EGFRvA protein stability.

EGFR CBL

1.34e-05374227059931
Pubmed

Identification of the domain in ErbB2 that restricts ligand-induced degradation.

EGFR CBL

1.34e-05374218255265
Pubmed

Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization.

EGFR CBL

1.34e-05374212734385
Pubmed

The long noncoding RNA lnc-EGFR stimulates T-regulatory cells differentiation thus promoting hepatocellular carcinoma immune evasion.

EGFR CBL

1.34e-05374228541302
Pubmed

Smad7 Modulates Epidermal Growth Factor Receptor Turnover through Sequestration of c-Cbl.

EGFR CBL

1.34e-05374226055326
Pubmed

EGF-dependent association of phospholipase C-gamma1 with c-Cbl.

EGFR CBL

1.34e-05374212061819
Pubmed

Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells.

EGFR CBL

1.34e-05374220562913
Pubmed

Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops.

EGFR CBL

1.34e-05374212593795
Pubmed

The murine leukemia inhibition factor gene (Lif) is located on proximal chromosome 11, not chromosome 13.

LIF EGFR

1.34e-0537421477476
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

MAPKAP1 CDK17 TMEM201 MTX2 SF3B1 EGFR TSR1 SF3A1 PPP1R15B RRP12 PPA2 CHD1 ADGRL2

1.39e-051487741333957083
Cytoband5q23.1

LVRN TNFAIP8

8.76e-04277425q23.1
CytobandEnsembl 112 genes in cytogenetic band chr2q23

TNFAIP6 NEB

3.35e-0353742chr2q23
Cytoband22q12.2

LIF SF3A1

4.00e-035874222q12.2
GeneFamilyCD molecules|Type II classical cadherins

CDH20 CDH5 CDH11 CDH12

2.35e-08134541186
GeneFamilyCadherin related

FAT4 CDHR2

8.04e-041745224
CoexpressionGSE45365_NK_CELL_VS_BCELL_UP

MON2 LIF TSR1 PPP1R15B DUSP6 TNFAIP6 CBL CDH11

9.05e-08198748M10031
CoexpressionHAY_BONE_MARROW_STROMAL

MAGI1 SLCO1C1 ABCA6 EGFR NAV3 MYO1B APOB TNFAIP6 ADGRL2 CDH5 PTGIS CDH11

1.51e-067677412M39209
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

CDK17 MTX2 PSME4 UPF2 EGFR PIK3C3 USP9X NAV3 MYO1B CHD1 TNFAIP8 CNOT2

4.65e-068567412M4500
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

CDK17 MTX2 UPF2 EGFR PIK3C3 USP9X MYO1B CHD1 CNOT2

6.53e-06466749M13522
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

CDK17 KMT2C SF3B1 SLC18A2 USP9X SF3A1 PPP1R15B DUSP6 EPC1 LPIN2 CHD1 TNFAIP8 CBL CNOT2 DDX5

1.51e-0514927415M40023
CoexpressionGSE27786_BCELL_VS_NKTCELL_UP

MON2 SF3B1 PSME4 BST1 CHD1 CNOT2

2.20e-05200746M4808
CoexpressionBOQUEST_STEM_CELL_UP

LIF ABCA6 EGFR TNFAIP6 PTGIS CDH11

9.68e-05261746M1834
CoexpressionCUI_TCF21_TARGETS_2_DN

HIPK3 KMT2C FUT11 USP9X DUSP6 LPIN2 MYO1B TNFAIP8 CBL CDH5

1.39e-048547410M1533
CoexpressionPATEL_SKIN_OF_BODY_ZOSTAVAX_AGE_70_93YO_VZV_CHALLENGE_6HR_UP

CDK17 PPP1R15B DUSP6 MYO1B CHD1 TNFAIP6

1.75e-04291746M41002
CoexpressionCUI_TCF21_TARGETS_2_DN

HIPK3 KMT2C FUT11 USP9X DUSP6 LPIN2 MYO1B TNFAIP8 CBL CDH5

1.91e-048887410MM1018
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

PIK3C3 NAV3 CHD1 TNFAIP8 ADGRL2 CNOT2

2.06e-04300746M8702
CoexpressionGSE13411_NAIVE_VS_MEMORY_BCELL_UP

HIPK3 SLCO1C1 ABCA6 NAV3 NEB

2.14e-04192745M3245
CoexpressionDESCARTES_FETAL_LUNG_MESOTHELIAL_CELLS

LIF CDH20 BST1 PTGIS

2.26e-04105744M40242
CoexpressionGSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_DN

LIF IRF4 AKR1A1 TNFAIP8 PTGIS

2.41e-04197745M8133
CoexpressionGSE360_L_MAJOR_VS_T_GONDII_MAC_UP

SLC18A2 CLK3 AKR1A1 TNFAIP6 CDH11

2.41e-04197745M5243
CoexpressionGSE3982_DC_VS_NEUTROPHIL_DN

SLCO1C1 USP9X LPIN2 ACAD10 TNFAIP6

2.41e-04197745M5462
CoexpressionGSE17186_MEMORY_VS_CD21HIGH_TRANSITIONAL_BCELL_UP

MAGI1 IRF4 APOB NEB CNOT2

2.47e-04198745M7200
CoexpressionGSE22033_UNTREATED_VS_ROSIGLITAZONE_TREATED_MEF_DN

LIF RRP12 LPIN2 IRF4 CHD1

2.53e-04199745M7690
CoexpressionGSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_UP

MTX2 TSR1 GLDC IRF4 TNFAIP8

2.53e-04199745M9414
CoexpressionGSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_DN

RELN BST1 CLK3 AKR1A1 TNFAIP6

2.53e-04199745M5255
CoexpressionGSE1460_CORD_VS_ADULT_BLOOD_NAIVE_CD4_TCELL_DN

SF3B1 PIK3C3 USP9X SF3A1 DDX5

2.53e-04199745M3481
CoexpressionKAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN

TSR1 DUSP6 TNFAIP6 PCCB DDX5

2.53e-04199745M3028
CoexpressionGSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_UP

DUSP6 LPIN2 NAV3 PTGIS APOBEC4

2.59e-04200745M5280
CoexpressionGSE16385_ROSIGLITAZONE_VS_UNTREATED_IFNG_TNF_STIM_MACROPHAGE_UP

CENPN TSR1 DUSP6 MYO1B IRF4

2.59e-04200745M7894
CoexpressionGSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_UP

LIF CDK17 TMEM201 PPP1R15B DUSP6

2.59e-04200745M9881
CoexpressionGSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN

CDK17 SLCO1C1 CLK3 DUSP6 LPIN2

2.59e-04200745M7531
CoexpressionGSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_UP

POLR1A UPF2 KIAA1958 IRF4 NEB

2.59e-04200745M4313
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SF3B1 UPF2 DUSP6 CHD1 TNFAIP8 DDX5

6.97e-07187746663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

MON2 CDK17 KMT2C PPP1R15B RRP12 CHD1

8.13e-0719274647646d7e4990be85072987f92bf18d52f8da752e
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RELN NAV3 APOB NEB

1.39e-051847452cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RELN NAV3 APOB NEB

1.39e-05184745ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RELN NAV3 APOB NEB

1.39e-051847452b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

EGFR EPC1 MYO1B TNFAIP6 CDH11

1.50e-05187745a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

FAT4 ABCA6 NAV3 ADGRL2 CDH11

1.50e-05187745bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

MON2 CDK17 KMT2C USP9X CHD1

1.54e-05188745ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 FAT4 NAV3 ADGRL2 CDH5

1.54e-05188745117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCell-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

LIF SLC18A2 NAV3 TNFAIP6 CDH11

1.54e-05188745038f48e8daaeb72716e975d22a6b004a90654960
ToppCellControl-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

MAGI1 ADGRL2 CDH5 PTGIS CDH11

1.58e-05189745f83f7521e377ded1522639e9a35c98b3e2725bac
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LVRN ABCA6 EGFR CHD1 TNFAIP6

1.66e-051917457d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCellControl-Endothelial-VE_Venous|Control / Disease state, Lineage and Cell class

MAGI1 ADGRL2 CDH5 PTGIS CDH11

1.66e-05191745617546cf4883dedf3323e03a53ba5adec334cf8e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA6 EGFR CHD1 TNFAIP6 PTGIS

1.70e-0519274511088878043a6ff95ba1970361256a82e434b80a
ToppCellLA-14._Fibroblast_III|LA / Chamber and Cluster_Paper

LIF ABCA6 EGFR CHD1 TNFAIP6

1.75e-051937457426c291bac59e539c427bcaae18abc7d397d44e
ToppCellIPF-Endothelial-VE_Venous|IPF / Disease state, Lineage and Cell class

MAGI1 NAV3 ADGRL2 CDH5 PTGIS

1.75e-0519374529a655fa80feaabe846c90a28363b037e22d24ae
ToppCellIPF-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

MAGI1 NAV3 ADGRL2 CDH5 PTGIS

1.75e-05193745ef66a46e7ab44fcc4005a23416e6da478a4cce37
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FAT4 ABCA6 EGFR ADGRL2 CDH11

1.79e-05194745b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 FAT4 NAV3 ADGRL2 CDH5

1.79e-0519474571ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellCOPD-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

MAGI1 EGFR NAV3 ADGRL2 CDH5

1.79e-0519474568705a6eca947c5b42b943d5224a7aef2a744007
ToppCellLA-14._Fibroblast_III|World / Chamber and Cluster_Paper

LIF ABCA6 EGFR CHD1 TNFAIP6

1.79e-05194745803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCellCOPD-Endothelial-VE_Capillary_B|COPD / Disease state, Lineage and Cell class

MAGI1 EGFR NAV3 ADGRL2 CDH5

1.79e-0519474518b7f901c12ca4f21f9a1eafd092aefe4d668b6d
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LVRN FAT4 ABCA6 NAV3 PTGIS

1.84e-05195745f54bc4454270ff06e85596f98199372b50d0179f
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FAT4 ABCA6 EGFR ADGRL2 CDH11

1.84e-051957450e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPIN2 NAV3 MYO1B ADGRL2 DDX5

1.84e-05195745a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIF ABCA6 EGFR TNFAIP6 PTGIS

1.84e-05195745fc43cd295f2cc3f6e9442232e028944f011c82cc
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA6 EGFR CHD1 TNFAIP6 NEB

1.84e-051957455c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellControl-Stromal-Fibroblast|Control / Disease state, Lineage and Cell class

ABCA6 EGFR NAV3 PTGIS CDH11

1.88e-051967457ca94477498a84cafcdd9933ee92a6cbde76c70e
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 ABCA6 NAV3 PTGIS CDH11

1.93e-051977450dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellCOPD-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

FAT4 ABCA6 EGFR NAV3 CDH11

1.93e-05197745d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLCO1C1 EGFR MYO1B PTGIS CDH11

1.93e-05197745c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCellCOPD-Stromal|COPD / Disease state, Lineage and Cell class

ABCA6 EGFR NAV3 PTGIS CDH11

1.93e-05197745d5390d86acaa8c39f1da893e8d2271f9ed2951d7
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 DUSP6 ADGRL2 CDH5 PTGIS

1.98e-05198745d5990cab01de6e6f3757f5a50ef70ced711bb1fa
ToppCellControl-Stromal|Control / Disease state, Lineage and Cell class

ABCA6 EGFR NAV3 PTGIS CDH11

1.98e-05198745ae726b6b7f0a4107899be4d32ac256ffa0bd8d59
ToppCellCOPD-Stromal-Fibroblast|COPD / Disease state, Lineage and Cell class

ABCA6 EGFR NAV3 PTGIS CDH11

1.98e-051987457904af61473cb20064f7a3a1e1bfe8d5913cf317
ToppCellstromal_cell|World / Lineage and Cell class

EGFR APOB TNFAIP6 ADGRL2 CDH11

2.02e-05199745507a82d0529b5b1fa5aebcfe43db53f0b6e3f8f0
ToppCellstromal_cell-stromal_cell|World / Lineage and Cell class

EGFR APOB TNFAIP6 ADGRL2 CDH11

2.02e-0519974574262363a34da3a1eb55ab375fd61ddd7bb39b23
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-tip_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MAGI1 DUSP6 MYO1B ADGRL2 CDH5

2.02e-051997451c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCell10x5'v1-week_14-16-Endothelial-stroma-tip_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MAGI1 DUSP6 MYO1B ADGRL2 CDH5

2.07e-0520074577ac1aa73c16a4f595ff01c6b4e171e0b8fed1e6
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 ABCA6 TNFAIP6 PTGIS CDH11

2.07e-05200745a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 ABCA6 NAV3 PTGIS CDH11

2.07e-05200745b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 ABCA6 NAV3 PTGIS CDH11

2.07e-05200745cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 ABCA6 NAV3 PTGIS CDH11

2.07e-052007453dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 ABCA6 NAV3 PTGIS CDH11

2.07e-05200745c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Macroglial|GW23 / Sample Type, Dataset, Time_group, and Cell type.

CDH20 SLCO1C1 EGFR DUSP6 PCCB

2.07e-0520074570c2e577efb6b6fe8f9d970d7ecc470788efb85b
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 ABCA6 NAV3 PTGIS CDH11

2.07e-052007450c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellCOVID-19-Heart-Fib_+_CM|COVID-19 / Disease (COVID-19 only), tissue and cell type

LVRN SRL NEB PTGIS

3.66e-05112744d00ee6b19e41a35450681fe676885983536d6292
ToppCellASK440-Endothelial-Endothelium|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq

DUSP6 ADGRL2 CDH5 PTGIS

5.11e-051227442f76ec3b527e9528fbb006599a96e8bbdf9e0e62
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BMP3 RELN CDH20 EGFR

1.08e-041487445e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

CDK17 KMT2C PSME4 CHD1

1.32e-041567441545169694f686d28648a68b552c2ae606599d66
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BMP3 RELN CDH20 EGFR

1.36e-04157744516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDHR2 TECTA NEB CDH12

1.53e-04162744bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 NAV3 ADGRL2 CDH5

1.57e-04163744977a970b1296234c22178420294cea73506ee02f
ToppCellAdult-Mesenchymal-myofibroblast_cell-D231|Adult / Lineage, Cell type, age group and donor

LIF FAT4 ABCA6 CDH11

1.61e-041647443d8ff70fe5582d1fb56b338be8b76fa1428b3657
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

FUT11 TNFAIP8 TNFAIP6 NLRC4

1.61e-041647443c15e9b8403b03d67f6ecd7861dc19f1261e3244
ToppCellEndothelial-endothelial_cell_of_bronchial_vessel|World / Lineage, Cell type, age group and donor

MAGI1 NAV3 ADGRL2 CDH5

1.64e-0416574484e553d699ac56df89a77248f7308b9133e1b683
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

MAGI1 MYO1B CDH11 PRIMPOL

1.76e-041687441bc6a1915d48f547385ed4f44e118bcc8a4a7b6c
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

MAGI1 MYO1B CDH11 PRIMPOL

1.76e-0416874469f534de0f9a293047bea03cb1b78551087a8df5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA6 NAV3 IRF4 TNFAIP6

1.76e-041687444b2d29a7843bf45922038c093ca7ec0600756adc
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|Myeloid_cells / Location, Cell class and cell subclass

TMEM201 PITRM1 CCDC15 NEB

1.80e-04169744dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAT4 ABCA6 ADGRL2 CDH11

1.80e-04169744c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

MAGI1 EGFR MYO1B ADGRL2

1.84e-04170744e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA6 NAV3 IRF4 TNFAIP6

1.88e-041717445d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CDK17 FAT4 SRL PTGIS

1.88e-041717441597459c971d6befa991d59dc66b41b6a522f797
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LVRN ABCA6 TECTA PTGIS

1.93e-04172744e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell343B-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TMEM201 ACAD10 TNFAIP6 ADGRL2

1.93e-04172744eb199c279fe8a2551121db37e9556893197d33ff
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

TMEM201 PITRM1 CCDC15 NEB

1.93e-04172744f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCell343B-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TMEM201 ACAD10 TNFAIP6 ADGRL2

1.93e-04172744709c6b77a7a52b873eefb6caca28a41291d384af
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4-5_RORB_ASCL1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN CDH20 SRL PTGIS

1.97e-041737442e35bf2b5534a289d93a09faae660f665c131062
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA6 EGFR ADGRL2 CDH11

2.01e-04174744f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D231|Adult / Lineage, Cell type, age group and donor

FAT4 ADGRL2 CDH5 PTGIS

2.01e-041747442dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA6 NAV3 PTGIS CDH11

2.06e-04175744795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA6 EGFR TNFAIP6 PTGIS

2.10e-04176744fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA6 EGFR TNFAIP6 PTGIS

2.10e-04176744f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP3 CDHR2 USP9X LPIN2

2.10e-041767441dd54bfaa58541de51e5a8328651d390833bd480
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIF SLC18A2 PPP1R15B CDH12

2.15e-0417774415553c7cd7826c80086daa76af4224f32dde53a6
ToppCell356C-Fibroblasts-Fibroblast-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

NAV3 NEB PTGIS CDH11

2.20e-04178744a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell356C-Fibroblasts-Fibroblast-E|356C / Donor, Lineage, Cell class and subclass (all cells)

NAV3 NEB PTGIS CDH11

2.20e-04178744371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCell3'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LIF SLC18A2 DUSP6 TNFAIP8

2.24e-041797449dd8d19050223cdebec2579014892b759e5e9de8
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 RELN EGFR MYO1B

2.24e-04179744c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAGI1 CDK17 FAT4 CDH5

2.24e-041797442a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI1 EGFR TNFAIP8 CDH12

2.29e-04180744cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAT4 ABCA6 ADGRL2 CDH11

2.29e-04180744f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLDC PPA2 APOB AKR1A1

2.34e-04181744bec7076efe94898213a62db72d171d737949977e
ToppCelldroplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 NAV3 MYO1B CDH5

2.34e-0418174492d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLDC PPA2 APOB AKR1A1

2.34e-04181744cf149b30b814cf87c9e923ef502cadf7fe4a3597
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA6 EGFR GLDC ACAD10

2.39e-04182744770ce9f3f4538d0181a0181543841bc964c68274
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA6 NAV3 TNFAIP6 PTGIS

2.39e-041827443dfa9187e9d2bab1d199079d29209c4648220ada
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP3 MYO1B PTGIS CDH11

2.39e-04182744c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP3 MYO1B PTGIS CDH11

2.39e-04182744dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCelldroplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 NAV3 MYO1B CDH5

2.39e-0418274481279877b920b5a1bc991a07d3031d6458700fe3
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA6 EGFR GLDC ACAD10

2.39e-0418274477ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA6 EGFR GLDC ACAD10

2.39e-041827444921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAGI1 RELN NAV3 CDH5

2.44e-041837444d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA6 EGFR GLDC ACAD10

2.44e-04183744d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCellIPF-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

LIF EGFR PTGIS CDH11

2.44e-041837447df20e3172a1220ff427f30181f4f0c3b7fe2d42
ToppCellControl-Endothelial_cells-Pulmonary_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

NAV3 ADGRL2 CDH5 PTGIS

2.44e-0418374446be9f96755c7b65aeac061d95d15abeb6466034
ToppCelldroplet-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP3 MYO1B PTGIS CDH11

2.49e-0418474489ac32e374a4379e4a6c6ea7603b1378b77c147f
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BMP3 MYO1B PTGIS CDH11

2.49e-04184744924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCelldroplet-Kidney-nan-18m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSME4 GLDC APOB AKR1A1

2.49e-04184744e02859bbac36dbbd55d7ae8cb5e46b764d7c6381
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

KMT2C IRF4 NEB DDX5

6.94e-0549494GAVISH_3CA_MALIGNANT_METAPROGRAM_41_UNASSIGNED
DrugPantothenic acid calcium salt monohydrate [63409-48-3]; Up 200; 8uM; PC3; HT_HG-U133A

BST1 SLC18A2 RRP12 MYO1B TNFAIP6 CBL CDH12

3.72e-061987474189_UP
DiseaseAlcoholic Intoxication, Chronic

EGFR SLC18A2 AKR1A1 CDH5 CDH11 CDH12

5.43e-05268736C0001973
DiseaseSquamous cell carcinoma of esophagus

KMT2C FAT4 EGFR TNFAIP8

9.26e-0595734C0279626
DiseaseHereditary Autoinflammatory Diseases

LPIN2 NLRC4

1.26e-047732C0751422
Diseasetotal lipids in very small VLDL measurement

ABCA6 APOB PCCB

1.91e-0445733EFO_0022156
Diseasefree cholesterol in very small VLDL measurement

ABCA6 APOB PCCB

2.18e-0447733EFO_0022275
Diseasetriglycerides to total lipids in medium LDL percentage

ABCA6 APOB PCCB

2.62e-0450733EFO_0022334
Diseasephospholipids in very small VLDL measurement

ABCA6 APOB PCCB

2.78e-0451733EFO_0022300
DiseaseAstigmatism

LVRN MAGI1 BMP3 EGFR

3.00e-04129734HP_0000483
DiseaseColorectal Carcinoma

KMT2C ABCA6 EGFR SF3A1 MYO1B CHD1 APOB CDH5

3.40e-04702738C0009402
DiseaseMental Depression

LIF RELN SLCO1C1 SLC18A2 DUSP6

4.24e-04254735C0011570
Diseasetriglycerides to total lipids in small LDL percentage

ABCA6 APOB PCCB

4.28e-0459733EFO_0022337
Diseasetriglycerides to total lipids in IDL percentage

ABCA6 APOB PCCB

5.19e-0463733EFO_0022329
Diseasecholesteryl esters to total lipids in very small VLDL percentage

ABCA6 APOB PCCB

7.36e-0471733EFO_0022259
DiseaseDepressive disorder

LIF RELN SLCO1C1 SLC18A2 DUSP6

7.59e-04289735C0011581
Diseasefree cholesterol to total lipids in large LDL percentage

ABCA6 APOB PCCB

8.30e-0474733EFO_0022280
Diseaseblood urea nitrogen measurement

CDH20 CENPN EGFR ACAD10 ADGRL2 PCCB

8.95e-04452736EFO_0004741
Diseasetype 1 diabetes mellitus (biomarker_via_orthology)

EGFR CBL

1.00e-0319732DOID:9744 (biomarker_via_orthology)
Diseasesucrose liking measurement

RELN CDH20

1.11e-0320732EFO_0010157
Diseasesphingomyelin 16:0 measurement

MYO1B TNFAIP6

1.11e-0320732EFO_0010391
DiseaseIntrahepatic Cholangiocarcinoma

KMT2C EGFR

1.61e-0324732C0345905
DiseaseExtrahepatic Cholangiocarcinoma

KMT2C EGFR

1.61e-0324732C3805278
Diseasecortical thickness

MON2 MAGI1 RELN SF3B1 CDH20 EGFR NAV3 PCCB CDH11

1.67e-031113739EFO_0004840
Diseaselobe attachment

MAGI1 FAT4 MTX2 TNFAIP8

1.75e-03207734EFO_0007667
DiseaseCholangiocarcinoma

KMT2C EGFR

1.89e-0326732C0206698
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

ABCA6 APOB PCCB

1.92e-0399733EFO_0004611, EFO_0007878
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

ABCA6 APOB PCCB

2.09e-03102733EFO_0004329, EFO_0004611

Protein segments in the cluster

PeptideGeneStartEntry
LPVFNAKDLNQYDFP

EPC1

361

Q9H2F5
PIKGFFADYEIPNLQ

BST1

201

Q10588
PLQNNELPGAEYQYK

BMP3

296

P12645
EALESYPLNNAFPGQ

APOBEC4

256

Q8WW27
YFNILDVNDNPPIFS

FAT4

1931

Q6V0I7
EFKNELYFLSPGQLP

ABCA6

886

Q8N139
TFEFLKENNFQPYPL

CLK3

391

P49761
SNNFYLPNQKSFLPL

ACAD10

156

Q6JQN1
NNNFILRYSLEFGPP

ADGRL2

381

O95490
YFNPKLPRNEIFFSN

LVRN

451

Q6Q4G3
QRNPFYPKNFLTVGD

DNAI2

371

Q9GZS0
DENDNAPEFAKPYQP

CDH5

471

P33151
KPPDNNEFYNKQEAL

CHD1

766

O14646
YTNINFPNLKEEFPD

KMT2C

1656

Q8NEZ4
KFPQYLPLSAEDNLG

MAGI1

286

Q96QZ7
LLDGYNEFKPQNCPE

NLRC4

246

Q9NPP4
NLDQVLFPYPEDNGQ

IRF4

286

Q15306
CNLFNYILNADGPAP

EIF3L

161

Q9Y262
YYTAQGEPFPNNLDK

LIF

66

P15018
KPVLNFYEANFPANV

DDX5

91

P17844
FNSIDKNKPPNYANG

NAV3

276

Q8IVL0
GYLEKLQINSPPFDQ

CDK17

156

Q00537
SNEILPYANFIPKEF

MON2

1531

Q7Z3U7
NLYDFLKQNKFSPLP

HIPK3

281

Q9H422
INPTLPQNFYEKPAF

RELN

1231

P78509
AAQAEYIEKFANPFP

PCCB

481

P05166
SLDNPDYQQDFFPKE

EGFR

1166

P00533
DYQQDFFPKEAKPNG

EGFR

1171

P00533
EGNLIFDPNNYLPKE

APOB

656

P04114
VNDNAPYFLPENKTF

CDHR2

921

Q9BYE9
QDINDNEPKFLDGPY

CDH20

156

Q9HBT6
NDPLLPNYLNGFECF

FUT11

376

Q495W5
VNDNAPKFAAPYEGF

CDH11

481

P55287
FGDYPQPQLEFAQYK

CENPN

256

Q96H22
FSEKPVPLNFNQQEY

KRCC1

111

Q9NPI7
FYLFPDGRNQNPDLT

CBL

336

P22681
QDINDNEPKFLDGPY

CDH12

151

P55289
TYDLFLNLEGNPPVN

MLLT1

101

Q03111
PNLPNLFENAGEFKY

DUSP6

241

Q16828
LYFDLEFNKPANPGA

PRIMPOL

111

Q96LW4
PEKQQPFQNLLKEYF

UPF2

346

Q9HAU5
PYFFNKQPTELDALV

MTX2

201

O75431
AEKLFNPNTNLYFGD

PHYHIPL

256

Q96FC7
DVFGYPQQFEDKPAL

USP9X

1616

Q93008
GPRQAFEFPQINYQK

RPE65

411

Q16518
FLQPKQFPFLASNYE

POLR1A

1031

O95602
PEVFKYNRFLNPDGS

PTGIS

401

Q16647
QNFFRKYAPSENGPN

PIK3C3

701

Q8NEB9
YPFSTQNPKDFQNLL

PITRM1

146

Q5JRX3
LQLNNPFNEYSKFDG

MAPKAP1

151

Q9BPZ7
YKVPDGKPENQFAFN

PPA2

241

Q9H2U2
EFLAALYNPFGNFKP

TNFAIP8

166

O95379
NSDDPYNPLNFKAPF

PPP1R15B

561

Q5SWA1
INNPKFNFLNPNDPY

SF3A1

76

Q15459
AKNFLPILFNLYGQP

RRP12

686

Q5JTH9
ANFYQPGFGKPQVDR

EIF4ENIF1

641

Q9NRA8
YAFERGDNPFPKNAD

AKR1A1

116

P14550
QDQDFLPRDQGYLPK

CCDC15

581

Q0P6D6
GLNLNSPENLYPKFA

CNOT2

386

Q9NZN8
CGNYNKNPLDDFLRP

TECTA

461

O75443
FKSPGFPNEYEDNQI

TNFAIP6

146

P98066
PKENLPQDYARIFQF

TSR1

516

Q2NL82
SGNLPFLKPDDIQYF

SF3B1

461

O75533
PNREAYKDFFGINPI

SRL

396

Q86TD4
DFLPSLKNLFGNPVY

SLCO1C1

341

Q9NYB5
FQENGDYNKPIPAQY

TMEM201

76

Q5SNT2
PLFFKIAPVENDNSY

PSME4

1601

Q14997
PFAKNIYGLIAPNFG

SLC18A2

376

Q05940
PEIINENGNPSYKYF

TXNDC12

126

O95881
PFVPLDQAQGYQQLF

GLDC

581

P23378
DPVDFLAEYLFKNNP

AK7

706

Q96M32
GDIELLKDPQNQPYF

KIAA1958

581

Q8N8K9
SKQPFYAAFGNRPND

LPIN2

801

Q92539
QPFQGAYLEINKNPK

MYO1B

961

O43795
PDLPQFLQAKCNAYN

NEB

1276

P20929