Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane-ephrin receptor activity	EPHA6 EPHA3 EPHA5	7.41e-06	15	52	3	GO:0005005
GeneOntologyMolecularFunction	ephrin receptor activity	EPHA6 EPHA3 EPHA5	1.57e-05	19	52	3	GO:0005003
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	EPHA6 KDR EPHA3 EPHA5	2.46e-05	65	52	4	GO:0004714
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	EPHA6 KDR EPHA3 EPHA5	7.08e-05	85	52	4	GO:0019199
GeneOntologyMolecularFunction	GPI-linked ephrin receptor activity	EPHA3 EPHA5	1.39e-04	7	52	2	GO:0005004
GeneOntologyMolecularFunction	protein tyrosine kinase activity	EPHA6 KDR EPHA3 EPHA5	5.51e-04	145	52	4	GO:0004713
GeneOntologyMolecularFunction	granulocyte colony-stimulating factor receptor binding	CEACAM5 CEACAM7	5.93e-04	14	52	2	GO:0005130
GeneOntologyMolecularFunction	actin binding	KLHL5 CEACAM5 KLHL1 FERMT1 CEACAM7 MACF1	1.48e-03	479	52	6	GO:0003779
GeneOntologyMolecularFunction	GPI anchor binding	CEACAM5 CEACAM7	1.62e-03	23	52	2	GO:0034235
GeneOntologyBiologicalProcess	serine import into mitochondrion	SFXN3 SFXN2	1.94e-05	3	53	2	GO:0140300
GeneOntologyBiologicalProcess	positive regulation of vasculogenesis	CEACAM5 CEACAM7 KDR	3.12e-05	24	53	3	GO:2001214
GeneOntologyBiologicalProcess	regulation of vasculogenesis	CEACAM5 CEACAM7 KDR	5.58e-05	29	53	3	GO:2001212
GeneOntologyCellularComponent	cell projection membrane	EVC2 CEACAM5 FERMT1 CEACAM7 CD44 MACF1 TACR3	9.06e-05	431	52	7	GO:0031253
GeneOntologyCellularComponent	receptor complex	CEACAM5 CEACAM7 CD44 TAS1R2 KDR TRAV22 EPHA5	5.59e-04	581	52	7	GO:0043235
GeneOntologyCellularComponent	transforming growth factor beta ligand-receptor complex	CEACAM5 CEACAM7	7.12e-04	16	52	2	GO:0070021
Domain	RECEPTOR_TYR_KIN_V_2	EPHA6 EPHA3 EPHA5	7.25e-06	14	52	3	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHA6 EPHA3 EPHA5	7.25e-06	14	52	3	PS00790
Domain	Eph_TM	EPHA6 EPHA3 EPHA5	7.25e-06	14	52	3	IPR027936
Domain	Tyr_kinase_rcpt_V_CS	EPHA6 EPHA3 EPHA5	7.25e-06	14	52	3	IPR001426
Domain	EPH_lbd	EPHA6 EPHA3 EPHA5	7.25e-06	14	52	3	SM00615
Domain	Ephrin_lbd	EPHA6 EPHA3 EPHA5	7.25e-06	14	52	3	PF01404
Domain	EphA2_TM	EPHA6 EPHA3 EPHA5	7.25e-06	14	52	3	PF14575
Domain	Tyr_kinase_ephrin_rcpt	EPHA6 EPHA3 EPHA5	7.25e-06	14	52	3	IPR016257
Domain	Ephrin_rcpt_lig-bd_dom	EPHA6 EPHA3 EPHA5	7.25e-06	14	52	3	IPR001090
Domain	EPH_LBD	EPHA6 EPHA3 EPHA5	7.25e-06	14	52	3	PS51550
Domain	Ephrin_rec_like	EPHA6 EPHA3 EPHA5	4.48e-05	25	52	3	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHA6 EPHA3 EPHA5	4.48e-05	25	52	3	IPR011641
Domain	Mtc	SFXN3 SFXN2	7.56e-05	5	52	2	PF03820
Domain	Mtc	SFXN3 SFXN2	7.56e-05	5	52	2	IPR004686
Domain	TyrKc	EPHA6 KDR EPHA3 EPHA5	1.05e-04	88	52	4	SM00219
Domain	Tyr_kinase_cat_dom	EPHA6 KDR EPHA3 EPHA5	1.05e-04	88	52	4	IPR020635
Domain	PROTEIN_KINASE_TYR	EPHA6 KDR EPHA3 EPHA5	1.53e-04	97	52	4	PS00109
Domain	Tyr_kinase_AS	EPHA6 KDR EPHA3 EPHA5	1.53e-04	97	52	4	IPR008266
Domain	Pkinase_Tyr	EPHA6 KDR EPHA3 EPHA5	4.55e-04	129	52	4	PF07714
Domain	Kelch	KLHL5 KLHL1 KBTBD12	5.64e-04	58	52	3	SM00612
Domain	Ser-Thr/Tyr_kinase_cat_dom	EPHA6 KDR EPHA3 EPHA5	5.87e-04	138	52	4	IPR001245
Domain	BACK	KLHL5 KLHL1 KBTBD12	6.23e-04	60	52	3	SM00875
Domain	BACK	KLHL5 KLHL1 KBTBD12	6.54e-04	61	52	3	PF07707
Domain	BACK	KLHL5 KLHL1 KBTBD12	6.54e-04	61	52	3	IPR011705
Domain	Kelch_1	KLHL5 KLHL1 KBTBD12	9.77e-04	70	52	3	PF01344
Domain	Kelch_1	KLHL5 KLHL1 KBTBD12	9.77e-04	70	52	3	IPR006652
Domain	BTB	KLHL5 KLHL1 KCTD3 KBTBD12	1.02e-03	160	52	4	PS50097
Domain	-	EPHA6 EPHA3 EPHA5	1.10e-03	73	52	3	2.60.120.260
Domain	BTB	KLHL5 KLHL1 KCTD3 KBTBD12	1.57e-03	180	52	4	SM00225
Domain	BTB/POZ_dom	KLHL5 KLHL1 KCTD3 KBTBD12	1.74e-03	185	52	4	IPR000210
Domain	SKP1/BTB/POZ	KLHL5 KLHL1 KCTD3 KBTBD12	1.88e-03	189	52	4	IPR011333
Domain	SAM	EPHA6 EPHA3 EPHA5	1.89e-03	88	52	3	SM00454
Domain	Ig_I-set	CEACAM5 CEACAM7 KDR ADGRF5	1.92e-03	190	52	4	IPR013098
Domain	I-set	CEACAM5 CEACAM7 KDR ADGRF5	1.92e-03	190	52	4	PF07679
Domain	Galactose-bd-like	EPHA6 EPHA3 EPHA5	2.28e-03	94	52	3	IPR008979
Domain	-	CEACAM5 EPHA6 CEACAM7 KDR ADGRF5 EPHA3 EPHA5	2.30e-03	663	52	7	2.60.40.10
Domain	SAM_DOMAIN	EPHA6 EPHA3 EPHA5	2.35e-03	95	52	3	PS50105
Domain	SAM	EPHA6 EPHA3 EPHA5	2.50e-03	97	52	3	IPR001660
Domain	-	KLHL5 KLHL1	2.55e-03	27	52	2	2.130.10.80
Domain	-	EPHA6 EPHA3 EPHA5	3.21e-03	106	52	3	1.10.150.50
Domain	Ig-like_fold	CEACAM5 EPHA6 CEACAM7 KDR ADGRF5 EPHA3 EPHA5	3.26e-03	706	52	7	IPR013783
Domain	Gal_Oxidase_b-propeller	KLHL5 KLHL1	4.03e-03	34	52	2	IPR015916
Domain	MAGE	MAGEL2 MAGED1	4.03e-03	34	52	2	SM01373
Domain	SAM/pointed	EPHA6 EPHA3 EPHA5	4.24e-03	117	52	3	IPR013761
Domain	MAGE	MAGEL2 MAGED1	4.51e-03	36	52	2	PS50838
Domain	MAGE	MAGEL2 MAGED1	4.51e-03	36	52	2	PF01454
Domain	MHD_dom	MAGEL2 MAGED1	4.51e-03	36	52	2	IPR002190
Domain	BTB	KLHL5 KLHL1 KBTBD12	5.80e-03	131	52	3	PF00651
Domain	Growth_fac_rcpt_	EPHA6 EPHA3 EPHA5	9.37e-03	156	52	3	IPR009030
Domain	Kelch-typ_b-propeller	KLHL5 KBTBD12	1.03e-02	55	52	2	IPR015915
Domain	fn3	EPHA6 EPHA3 EPHA5	1.04e-02	162	52	3	PF00041
Pathway	REACTOME_EPHA_MEDIATED_GROWTH_CONE_COLLAPSE	EPHA6 EPHA3 EPHA5	5.80e-05	29	37	3	M27309
Pathway	PID_EPHA_FWDPATHWAY	EPHA6 EPHA3 EPHA5	9.42e-05	34	37	3	M177
Pathway	REACTOME_EPH_EPHRIN_MEDIATED_REPULSION_OF_CELLS	EPHA6 EPHA3 EPHA5	3.18e-04	51	37	3	M27311
Pubmed	Opposing gradients of ephrin-As and EphA7 in the superior colliculus are essential for topographic mapping in the mammalian visual system.	EPHA6 EPHA3 EPHA5	7.05e-08	6	54	3	15996548
Pubmed	Mistargeting hippocampal axons by expression of a truncated Eph receptor.	EPHA6 EPHA3 EPHA5	1.97e-07	8	54	3	12124402
Pubmed	Embryonic expression of EphA receptor genes in mice supports their candidacy for involvement in cleft lip and palate.	EPHA6 EPHA3 EPHA5	4.21e-07	10	54	3	25073978
Pubmed	Quantitative assessment of computational models for retinotopic map formation.	EPHA6 EPHA3 EPHA5	4.21e-07	10	54	3	25367067
Pubmed	EphrinA5 Signaling Is Required for the Distinctive Targeting of Raphe Serotonin Neurons in the Forebrain.	EPHA6 EPHA3 EPHA5	4.21e-07	10	54	3	28197551
Pubmed	EphA receptors inhibit anti-CD3-induced apoptosis in thymocytes.	EPHA6 EPHA3 EPHA5	4.21e-07	10	54	3	16547242
Pubmed	Selective inhibition of spinal cord neurite outgrowth and cell survival by the Eph family ligand ephrin-A5.	EPHA6 EPHA3 EPHA5	5.79e-07	11	54	3	10559410
Pubmed	Eph-ephrin A system regulates murine blastocyst attachment and spreading.	EPHA6 EPHA3 EPHA5	1.00e-06	13	54	3	17039519
Pubmed	EphA family gene expression in the developing mouse neocortex: regional patterns reveal intrinsic programs and extrinsic influence.	EPHA6 EPHA3 EPHA5	1.00e-06	13	54	3	12528186
Pubmed	Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue.	EPHA6 EPHA3 EPHA5	1.27e-06	14	54	3	26941654
Pubmed	A role for the EphA family in the topographic targeting of vomeronasal axons.	EPHA6 EPHA3 EPHA5	1.27e-06	14	54	3	11222144
Pubmed	Human endothelin converting enzyme-2 (ECE2): characterization of mRNA species and chromosomal localization.	EEF1AKMT4-ECE2 ECE2	2.37e-06	2	54	2	11718899
Pubmed	Combined use of lysyl oxidase, carcino-embryonic antigen, and carbohydrate antigens improves the sensitivity of biomarkers in predicting lymph node metastasis and peritoneal metastasis in gastric cancer.	CEACAM5 LOX	2.37e-06	2	54	2	25060181
Pubmed	Predicting prognosis of rectal cancer patients with total mesorectal excision using molecular markers.	CEACAM5 CD44	2.37e-06	2	54	2	17589956
Pubmed	Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice.	EPHA6 EPHA3 EPHA5	2.37e-06	17	54	3	12217323
Pubmed	Expression of Ephs and ephrins in developing mouse inner ear.	EPHA6 EPHA3 EPHA5	3.37e-06	19	54	3	12684176
Pubmed	Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee.	EPHA6 EPHA3 EPHA5	4.61e-06	21	54	3	9267020
Pubmed	Eph receptors and ephrins demarcate cerebellar lobules before and during their formation.	EPHA6 EPHA3 EPHA5	4.61e-06	21	54	3	10495276
Pubmed	Developmental expression of Eph and ephrin family genes in mammalian small intestine.	EPHA6 EPHA3 EPHA5	4.61e-06	21	54	3	20112066
Pubmed	Roles of Eph receptors and ephrins in segmental patterning.	EPHA6 EPHA3 EPHA5	4.61e-06	21	54	3	11128993
Pubmed	Eph receptors and ephrins: regulators of guidance and assembly.	EPHA6 EPHA3 EPHA5	4.61e-06	21	54	3	10730216
Pubmed	Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling.	EPHA6 EPHA3 EPHA5	6.13e-06	23	54	3	19542359
Pubmed	Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions.	EPHA6 EPHA3 EPHA5	6.13e-06	23	54	3	25480914
Pubmed	Eph receptors and their ephrin ligands are expressed in developing mouse pancreas.	EPHA6 EPHA3 EPHA5	7.00e-06	24	54	3	16446123
Pubmed	EphrinA/EphA-induced ectodomain shedding of neural cell adhesion molecule regulates growth cone repulsion through ADAM10 metalloprotease.	EPHA3 EPHA5	7.09e-06	3	54	2	24117969
Pubmed	Identification of ocular regulatory functions of core histone variant H3.2.	EPHA3 EPHA5	7.09e-06	3	54	2	36529279
Pubmed	Targeted Sequencing Reveals Low-Frequency Variants in EPHA Genes as Markers of Paclitaxel-Induced Peripheral Neuropathy.	EPHA6 EPHA5	7.09e-06	3	54	2	27582484
Pubmed	Carcinoembryonic antigen-related cell adhesion molecule 4 (CEACAM4) is specifically expressed in medullary thyroid carcinoma cells.	CEACAM5 CEACAM7	7.09e-06	3	54	2	25152032
Pubmed	A Lox/CHOP-10 crosstalk governs osteogenic and adipogenic cell fate by MSCs.	LOX DDIT3	7.09e-06	3	54	2	30044535
Pubmed	A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis.	CD44 KDR	7.09e-06	3	54	2	19773544
Pubmed	The protein tyrosine kinase family of the human genome.	EPHA6 KDR EPHA3 EPHA5	8.71e-06	83	54	4	11114734
Pubmed	Disruption of ephrin signaling associates with disordered axophilic migration of the gonadotropin-releasing hormone neurons.	EPHA3 EPHA5	1.42e-05	4	54	2	15788771
Pubmed	Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development.	MAGEL2 MAGED1	1.42e-05	4	54	2	18930956
Pubmed	Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat.	CEACAM5 CEACAM7	1.42e-05	4	54	2	10436421
Pubmed	MOV10 Is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs.	TNRC6B UPF1	1.42e-05	4	54	2	24726324
Pubmed	Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E- and L-selectin in shear flow.	CEACAM5 CD44	1.42e-05	4	54	2	18375392
Pubmed	Compensatory Actions of Ldb Adaptor Proteins During Corticospinal Motor Neuron Differentiation.	EPHA6 EPHA3 EPHA5	1.87e-05	33	54	3	26830346
Pubmed	The ephrin signaling pathway regulates morphology and adhesion of mouse granulosa cells in vitro.	EPHA3 EPHA5	2.36e-05	5	54	2	23242526
Pubmed	SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism.	SFXN3 SFXN2	2.36e-05	5	54	2	30442778
Pubmed	Expression of ephrinA5 during development and potential involvement in the guidance of the mesostriatal pathway.	EPHA3 EPHA5	2.36e-05	5	54	2	19576892
Pubmed	Area specificity and topography of thalamocortical projections are controlled by ephrin/Eph genes.	EPHA3 EPHA5	3.54e-05	6	54	2	12895420
Pubmed	Quantitative genetic analysis of brain copper and zinc in BXD recombinant inbred mice.	EPHA6 EPHA3	3.54e-05	6	54	2	16910173
Pubmed	Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature.	EPHA6 EPHA3 EPHA5	3.89e-05	42	54	3	11439183
Pubmed	SCA-1/Ly6A Mesodermal Skeletal Progenitor Subpopulations Reveal Differential Commitment of Early Limb Bud Cells.	CD44 KDR	4.94e-05	7	54	2	34336823
Pubmed	Diagnostic and prognostic tissuemarkers in clear cell and papillary renal cell carcinoma.	CD44 KDR	4.94e-05	7	54	2	21694464
Pubmed	Novel Roles and Mechanism for Krüppel-like Factor 16 (KLF16) Regulation of Neurite Outgrowth and Ephrin Receptor A5 (EphA5) Expression in Retinal Ganglion Cells.	EPHA6 EPHA5	4.94e-05	7	54	2	27402841
Pubmed	Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping.	EPHA6 EPHA5	6.59e-05	8	54	2	10774725
Pubmed	Transcription factor Foxd1 is required for the specification of the temporal retina in mammals.	EPHA6 EPHA5	6.59e-05	8	54	2	21490208
Pubmed	A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice.	SFXN3 SFXN2	6.59e-05	8	54	2	11274051
Pubmed	NgBR is essential for endothelial cell glycosylation and vascular development.	KDR DDIT3	6.59e-05	8	54	2	26755743
Pubmed	Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse.	EPHA6 EPHA3 EPHA5	6.99e-05	51	54	3	19769959
Pubmed	Degenerate PCR-based cloning method for Eph receptors and analysis of their expression in the developing murine central nervous system and vasculature.	EPHA3 EPHA5	8.46e-05	9	54	2	11403717
Pubmed	Topographic guidance labels in a sensory projection to the forebrain.	EPHA3 EPHA5	8.46e-05	9	54	2	9883724
Pubmed	Novel CUL3 Variant Causing Familial Hyperkalemic Hypertension Impairs Regulation and Function of Ubiquitin Ligase Activity.	KLHL5 KLHL1 KCTD3	9.76e-05	57	54	3	34878901
Pubmed	Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns.	CDH20 EPHA3 EPHA5	1.03e-04	58	54	3	27568519
Pubmed	Prolonged endoplasmic reticulum stress alters placental morphology and causes low birth weight.	KDR DDIT3	1.06e-04	10	54	2	24370435
Pubmed	HOXA13 directly regulates EphA6 and EphA7 expression in the genital tubercle vascular endothelia.	EPHA6 EPHA5	1.06e-04	10	54	2	17304517
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	CEACAM5 CEACAM7 KDR ADGRF5	1.20e-04	162	54	4	25826454
Pubmed	Bidirectional ephrinB3/EphA4 signaling mediates the segregation of medial ganglionic eminence- and preoptic area-derived interneurons in the deep and superficial migratory stream.	EPHA3 EPHA5	1.29e-04	11	54	2	22171039
Pubmed	Competition is a driving force in topographic mapping.	EPHA6 EPHA5	1.29e-04	11	54	2	22065784
Pubmed	Formation of persistent hyperplastic primary vitreous in ephrin-A5-/- mice.	EPHA6 EPHA5	1.29e-04	11	54	2	24550361
Pubmed	Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase.	MAGEL2 MAGED1	1.29e-04	11	54	2	24911587
Pubmed	Expression of ephrin-A ligands and EphA receptors in the developing mouse tooth and its supporting tissues.	EPHA3 EPHA5	1.29e-04	11	54	2	15517401
Pubmed	Proximity labeling reveals dynamic changes in the SQSTM1 protein network.	MAGED1 KCTD3 TNRC6B UPF1 DCAF7	1.44e-04	322	54	5	39098523
Pubmed	EphrinA-EphA receptor interactions in mouse spinal neurulation: implications for neural fold fusion.	EPHA3 EPHA5	1.55e-04	12	54	2	19247962
Pubmed	Regulation of hepatic fibrosis by carcinoembryonic antigen-related cell adhesion molecule 1.	CEACAM5 CEACAM7	1.83e-04	13	54	2	34058224
Pubmed	A mouse carcinoembryonic antigen gene family member is a calcium-dependent cell adhesion molecule.	CEACAM5 CEACAM7	1.83e-04	13	54	2	1985902
Pubmed	Down-regulation of Bgp1(a) viral receptor by interferon-gamma is related to the antiviral state and resistance to mouse hepatitis virus 3 infection.	CEACAM5 CEACAM7	1.83e-04	13	54	2	10964771
Pubmed	Neutrophil Extracellular Trap-Associated CEACAM1 as a Putative Therapeutic Target to Prevent Metastatic Progression of Colon Carcinoma.	CEACAM5 CEACAM7	1.83e-04	13	54	2	32169849
Pubmed	CEACAM1+ myeloid cells control angiogenesis in inflammation.	CEACAM5 CEACAM7	1.83e-04	13	54	2	19273835
Pubmed	Mechanism of glucose intolerance in mice with dominant negative mutation of CEACAM1.	CEACAM5 CEACAM7	1.83e-04	13	54	2	16638824
Pubmed	Decreased osteoclastogenesis and high bone mass in mice with impaired insulin clearance due to liver-specific inactivation to CEACAM1.	CEACAM5 CEACAM7	1.83e-04	13	54	2	20044046
Pubmed	Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry.	CEACAM5 CEACAM7	1.83e-04	13	54	2	32150576
Pubmed	Host-related carcinoembryonic antigen cell adhesion molecule 1 promotes metastasis of colorectal cancer.	CEACAM5 CEACAM7	1.83e-04	13	54	2	22469976
Pubmed	Mouse hepatitis virus type 4 (JHM strains). induced fatal central nervous system disease. I. genetic control and murine neuron as the susceptible site of disease.	CEACAM5 CEACAM7	1.83e-04	13	54	2	6265583
Pubmed	CEACAM1 creates a pro-angiogenic tumor microenvironment that supports tumor vessel maturation.	CEACAM5 CEACAM7	1.83e-04	13	54	2	21532628
Pubmed	Structural and Molecular Evidence Suggesting Coronavirus-driven Evolution of Mouse Receptor.	CEACAM5 CEACAM7	1.83e-04	13	54	2	28035001
Pubmed	Insulin Sensitivity Is Retained in Mice with Endothelial Loss of Carcinoembryonic Antigen Cell Adhesion Molecule 1.	CEACAM5 CEACAM7	1.83e-04	13	54	2	34440862
Pubmed	CEACAM1 is a potent regulator of B cell receptor complex-induced activation.	CEACAM5 CEACAM7	1.83e-04	13	54	2	12832451
Pubmed	CEACAM1 confers resistance toward oxygen-induced vessel damage in a mouse model of retinopathy of prematurity.	CEACAM5 CEACAM7	1.83e-04	13	54	2	25406283
Pubmed	Interaction between altered insulin and lipid metabolism in CEACAM1-inactive transgenic mice.	CEACAM5 CEACAM7	1.83e-04	13	54	2	15316023
Pubmed	Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor.	CEACAM5 CEACAM7	1.83e-04	13	54	2	21670291
Pubmed	Investigations on the usefulness of CEACAMs as potential imaging targets for molecular imaging purposes.	CEACAM5 CEACAM7	1.83e-04	13	54	2	22162753
Pubmed	In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa.	CEACAM5 CEACAM7	1.83e-04	13	54	2	23935487
Pubmed	A mouse analogue of the human carcinoembryonic antigen.	CEACAM5 CEACAM7	1.83e-04	13	54	2	2702644
Pubmed	Several members of the mouse carcinoembryonic antigen-related glycoprotein family are functional receptors for the coronavirus mouse hepatitis virus-A59.	CEACAM5 CEACAM7	1.83e-04	13	54	2	8380065
Pubmed	The receptor for mouse hepatitis virus in the resistant mouse strain SJL is functional: implications for the requirement of a second factor for viral infection.	CEACAM5 CEACAM7	1.83e-04	13	54	2	1279194
Pubmed	Ceacam1a-/- mice are completely resistant to infection by murine coronavirus mouse hepatitis virus A59.	CEACAM5 CEACAM7	1.83e-04	13	54	2	15331748
Pubmed	Organ tropism of murine coronavirus does not correlate with the expression levels of the membrane-anchored or secreted isoforms of the carcinoembryonic antigen-related cell adhesion molecule 1 receptor.	CEACAM5 CEACAM7	1.83e-04	13	54	2	22673933
Pubmed	Tumor angiogenesis mediated by myeloid cells is negatively regulated by CEACAM1.	CEACAM5 CEACAM7	1.83e-04	13	54	2	22406619
Pubmed	Characterization and transcriptional activity of the mouse biliary glycoprotein 1 gene, a carcinoembryonic antigen-related gene.	CEACAM5 CEACAM7	1.83e-04	13	54	2	7628460
Pubmed	Exogenous carcinoembryonic antigen-related cell adhesion molecule 1 suppresses 2,4,6-trinitrobenzene sulfonic acid-induced ulcerative colitis in mice.	CEACAM5 CEACAM7	1.83e-04	13	54	2	25724769
Pubmed	High-fat diet amplifies renal renin angiotensin system expression, blood pressure elevation, and renal dysfunction caused by Ceacam1 null deletion.	CEACAM5 CEACAM7	1.83e-04	13	54	2	26374765
Pubmed	Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance.	CEACAM5 CEACAM7	1.83e-04	13	54	2	25972571
Pubmed	CEACAM1 deficiency delays important wound healing processes.	CEACAM5 CEACAM7	1.83e-04	13	54	2	22092845
Pubmed	Activation-induced expression of carcinoembryonic antigen-cell adhesion molecule 1 regulates mouse T lymphocyte function.	CEACAM5 CEACAM7	1.83e-04	13	54	2	11801635
Pubmed	Liver-specific reconstitution of CEACAM1 reverses the metabolic abnormalities caused by its global deletion in male mice.	CEACAM5 CEACAM7	1.83e-04	13	54	2	28913658
Pubmed	CEACAM1 negatively regulates platelet-collagen interactions and thrombus growth in vitro and in vivo.	CEACAM5 CEACAM7	1.83e-04	13	54	2	19008452
Pubmed	Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism.	CEACAM5 CEACAM7	1.83e-04	13	54	2	18544705
Pubmed	Expression of the mouse hepatitis virus receptor by central nervous system microglia.	CEACAM5 CEACAM7	1.83e-04	13	54	2	15220458
Cytoband	Ensembl 112 genes in cytogenetic band chr1p36	AUNIP TPRG1L PER3 TAS1R2 C1orf167	1.23e-03	681	54	5	chr1p36
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHA6 EPHA3 EPHA5	2.83e-06	14	37	3	1095
GeneFamily	Sideroflexins	SFXN3 SFXN2	4.06e-05	5	37	2	746
GeneFamily	Immunoglobulin like domain containing	CEACAM5 CEACAM7 KDR ADGRF5	6.31e-04	193	37	4	594
GeneFamily	Sterile alpha motif domain containing	EPHA6 EPHA3 EPHA5	7.68e-04	88	37	3	760
GeneFamily	CD molecules\|V-set domain containing\|Immunoglobulin like domain containing\|Carcinoembryonic antigen related cell adhesion molecule family	CEACAM5 CEACAM7	1.09e-03	24	37	2	906
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL5 KLHL1 KBTBD12	2.57e-03	134	37	3	861
GeneFamily	MAGE family	MAGEL2 MAGED1	3.03e-03	40	37	2	1136
GeneFamily	Kelch like\|BTB domain containing	KLHL5 KLHL1	3.33e-03	42	37	2	617
GeneFamily	Fibronectin type III domain containing	EPHA6 EPHA3 EPHA5	4.24e-03	160	37	3	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	CEACAM5 KDR ADGRF5	4.31e-03	161	37	3	593
GeneFamily	Adenosine receptors\|V-set domain containing	CEACAM5 CEACAM7 KDR	4.46e-03	163	37	3	590
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	MYO15B FERMT1	4.69e-03	50	37	2	1293
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	KLHL5 PINX1 MACF1 KDR ADGRF5 FAM167B	1.55e-07	200	54	6	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAGED1 LOX MACF1 EPHA3 EPHA5	3.77e-06	194	54	5	f2f7b9aad7588c8020a4850ff9333e1db8eafac7
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PINX1 MACF1 KDR ADGRF5 FAM167B	4.37e-06	200	54	5	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PINX1 MACF1 KDR ADGRF5 FAM167B	4.37e-06	200	54	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PINX1 MACF1 KDR ADGRF5 FAM167B	4.37e-06	200	54	5	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	PINX1 MACF1 KDR ADGRF5 FAM167B	4.37e-06	200	54	5	eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PINX1 MACF1 KDR ADGRF5 FAM167B	4.37e-06	200	54	5	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	LPS_only-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	PINX1 MACF1 KDR ADGRF5 FAM167B	4.37e-06	200	54	5	81e76508c9050d533853d5fd2f3097b27613d836
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	PINX1 MACF1 KDR ADGRF5 FAM167B	4.37e-06	200	54	5	4bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL19A1 KDR ADGRF5 FAM167B	3.75e-05	155	54	4	8fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCell	LPS_only-Myeloid-Monocytes,_Macrophages-T-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPHA6 KBTBD12 CEP97 PGBD5	4.04e-05	158	54	4	91d8c93af328c3bbebe1d8f019b94849ebc548c0
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	KLHL1 EPHA6 EPHA3 EPHA5	4.14e-05	159	54	4	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHA6 DNAH10 TACR3 EPHA5	4.45e-05	162	54	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	KLHL5 KLHL1 KDR ADGRF5	5.88e-05	174	54	4	b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell	facs-Aorta\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDR ADGRF5 EPHA3 FAM167B	6.14e-05	176	54	4	0b3491451be02c18a16cdb875645be47eb867a7f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDH20 EPHA6 EPHA3 EPHA5	6.56e-05	179	54	4	c815eb9f760fe4ca7a5e49beb224659f0b864f22
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAGED1 LOX MACF1 EPHA3	6.56e-05	179	54	4	b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Endothelial\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBB3 KDR ADGRF5 FAM167B	6.70e-05	180	54	4	f9b7d5eb7b6ea72253c89bdc351ad2b4a53f7d8e
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Endothelial-endothelial_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBB3 KDR ADGRF5 FAM167B	6.70e-05	180	54	4	53db6032eda0e590ae7e01c9c3b472785ea6782f
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Endothelial-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBB3 KDR ADGRF5 FAM167B	6.70e-05	180	54	4	28bc10b9d0e4430b952260014d8a6ff337860ac6
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MAGEL2 LOX FERMT1 EPHA5	7.00e-05	182	54	4	ba066ff9029cc052b76e2330ec168cb2e9b7e498
ToppCell	droplet-Liver-Npc-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL5 KDR ADGRF5 FAM167B	7.00e-05	182	54	4	dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL5 KDR ADGRF5 FAM167B	7.00e-05	182	54	4	010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL5 KDR ADGRF5 FAM167B	7.00e-05	182	54	4	b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL5 KLHL1 EPHA6 ECE2	7.45e-05	185	54	4	ae53aa2ecfe418a5dbd7d963a995bc06dab94f56
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBB3 KDR ADGRF5 FAM167B	7.77e-05	187	54	4	3548a9914c2b2f5d805798ce22ab26eab6d03897
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBB3 KDR ADGRF5 FAM167B	7.77e-05	187	54	4	f4de4b7af1fdfbd628b1f509c060c1079d2e5437
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBB3 KDR ADGRF5 FAM167B	7.77e-05	187	54	4	81754e965848b718be20ee97ce072ce426938a69
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL5 EPHA6 BEST3 ECE2	7.93e-05	188	54	4	8de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KLHL5 KCTD3 KDR ADGRF5	8.10e-05	189	54	4	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	EC-Sinusoidal_ECs\|World / Lineage and Cell class	CRYBB3 KDR ADGRF5 FAM167B	8.10e-05	189	54	4	9a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAGED1 LOX EPHA3 EPHA5	8.10e-05	189	54	4	3169476f98b7385706cb618c9ad64ae83a290ef0
ToppCell	droplet-Heart-HEART-1m-Endothelial-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PER3 PRSS27 KDR ADGRF5	8.10e-05	189	54	4	4225bbff4037eecc93a12abad3a38dd04b1e22be
ToppCell	PCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating1_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CRYBB3 KDR ADGRF5 FAM167B	8.26e-05	190	54	4	9a2244c3973aee7270646bf00db7727edb9decc5
ToppCell	E15.5-Mesenchymal\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAGED1 LOX EPHA3 EPHA5	8.78e-05	193	54	4	22a9f5b61f197757f72840b9cb849cdb20430e72
ToppCell	facs-Liver-Non-hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MACF1 KDR ADGRF5 FAM167B	8.78e-05	193	54	4	8084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAGED1 LOX EPHA3 EPHA5	8.78e-05	193	54	4	b637e1c47a98009e7d19a6daac78f888fd12748f
ToppCell	NS-critical-d_0-4-Epithelial-Squamous\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CEACAM5 PRSS27 NTHL1 CEACAM7	8.95e-05	194	54	4	614d0c25b56957c70f397abb169fd2a860eb1c06
ToppCell	COVID-19-kidney-Glomerular_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KLHL5 KDR ADGRF5 FAM167B	8.95e-05	194	54	4	660535b492445063d965095a50e1e299ce04c50a
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PER3 MACF1 KDR ADGRF5	8.95e-05	194	54	4	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	facs-Aorta-Heart-3m-Endothelial\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MACF1 KDR ADGRF5 FAM167B	9.13e-05	195	54	4	8493f2f60fc356af28b9c0e287d4cd8c8899c081
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAGED1 LOX MACF1 EPHA3	9.13e-05	195	54	4	cbe518b465b4ef32797ae6b608219207c08493df
ToppCell	PND03-Mesenchymal-Mesenchymal_structural\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAGED1 LOX MACF1 EPHA3	9.13e-05	195	54	4	136b06b0931a69b1241101f68c01c44c70365fd9
ToppCell	facs-Aorta-Heart-3m-Endothelial-aortic_endothelial_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MACF1 KDR ADGRF5 FAM167B	9.13e-05	195	54	4	5e5ca7bd94c9e924ed76f7ccac199be745d4c4eb
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-Late_cap\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KLHL5 KDR ADGRF5 FAM167B	9.13e-05	195	54	4	dfc5da514fb34a2c318a5c4c61f44049fa43960e
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAGED1 LOX MACF1 EPHA3	9.32e-05	196	54	4	2a885eed52f9b002c7995e11e450c7e8d7ae69e6
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAGED1 LOX MACF1 EPHA3	9.32e-05	196	54	4	14246f00c90741a5f8683f377e22e3a7c99661b9
ToppCell	E17.5-Mesenchymal\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAGED1 LOX MACF1 EPHA3	9.32e-05	196	54	4	b4ee991445b612506372b9361ebfe72cb59b811e
ToppCell	NS-critical-d_16-33-Epithelial-Squamous\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CEACAM5 PRSS27 NTHL1 CEACAM7	9.32e-05	196	54	4	97e16d9833e4083d719ca7058d5fc9b11edb37e3
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAGED1 LOX MACF1 EPHA3	9.32e-05	196	54	4	028a06ed92f1c058dcbeacd335625bf529e87a7b
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MACF1 KDR ADGRF5 FAM167B	9.50e-05	197	54	4	deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCell	moderate-Epithelial-Squamous\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CEACAM5 PRSS27 NTHL1 CEACAM7	9.50e-05	197	54	4	ab3c90a5b643b45d0b83939c6304b11f567c5d78
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KDR ADGRF5 GARIN1B FAM167B	9.50e-05	197	54	4	a312d9cf4ced949307eb9620be4eed926300b892
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MACF1 KDR ADGRF5 FAM167B	9.50e-05	197	54	4	a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCell	control-Epithelial-Squamous\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CEACAM5 PRSS27 NTHL1 CEACAM7	9.69e-05	198	54	4	6ba669ac1ed275ae309054941b1457e315766faa
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KDR ADGRF5 EPHA3 FAM167B	9.69e-05	198	54	4	b027a141ab531d0f5d6a26811a53427e7b0771dd
ToppCell	NS-moderate-d_07-13-Epithelial-Squamous\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CEACAM5 PRSS27 NTHL1 CEACAM7	9.69e-05	198	54	4	b7495369baba203490c067a58fc8456a778a12e4
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-intermediate_cap\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	KLHL5 KDR ADGRF5 FAM167B	9.69e-05	198	54	4	a75499f8f1630359b64717c300621aa3b1ab44d4
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MACF1 KDR ADGRF5 FAM167B	9.69e-05	198	54	4	f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCell	control-Epithelial-Squamous\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CEACAM5 PRSS27 NTHL1 CEACAM7	9.88e-05	199	54	4	e13dca7a055cdca53dd6c26c04b2a46d58b419b6
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	7034f57e282982c19c13ee8ab78eabaffa069e30
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	89a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	b70b7adb7c187e6253c7f0bb4c1f09c85ef7142c
ToppCell	LPS_anti-TNF-Endothelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	1d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	6f531a418ff25b59a543800cf4bce7b72404ce08
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PINX1 MACF1 KDR FAM167B	1.01e-04	200	54	4	2d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	58a7ece7dfdf6c46f2a50cbcb580574dec14c748
ToppCell	LPS_IL1RA_TNF-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	LPS_anti-TNF-Endothelial-Endothelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	60d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	432384faeade8e609154fab3d96c955a8ec868dd
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	PINX1 MACF1 KDR ADGRF5	1.01e-04	200	54	4	edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCell	Control_saline-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	3372c488a39fe812fa94e4f0564594186fea3db5
ToppCell	Control_saline-Endothelial-Endothelial-Alv_Gen_Intermediate\|Control_saline / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	041a34080120c9f613373c20dcc366292f558040
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	b1fadb2b5e37e0f51e079d8409c2647eef68dc3b
ToppCell	Control_saline-Endothelial-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PINX1 MACF1 KDR ADGRF5	1.01e-04	200	54	4	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	66f7e8ee63c828f17468e79a4b816346b33e8980
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PINX1 KDR ADGRF5 FAM167B	1.01e-04	200	54	4	f15fffefe372005c33e31845982e2d2714ac26af
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MAGEL2 COL19A1 TACR3	2.51e-04	101	54	3	cf52c93f523c5f25bd45519a1444ce7bd1d8b577
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MAGEL2 KLHL1 COL19A1	4.79e-04	126	54	3	84dce108561d4b745d19250c2ac0667d9e4ea17d
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Acinar_Adenocarcinoma-7\|TCGA-Lung / Sample_Type by Project: Shred V9	KCNK5 ADGRF5 EPHA3	5.25e-04	130	54	3	0219d0d5d21df08f816569c7eb34f1bfa095d29a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AUNIP CEACAM7 TACR3	5.49e-04	132	54	3	694b79dc31b8d7ef3c01962916d25980b76da33e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AUNIP CEACAM7 TACR3	5.49e-04	132	54	3	36bb06f9e97a8abbea4d06beff9e38641a5f0ff2
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	EVC2 TNRC6B MACF1	5.86e-04	135	54	3	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	(03)_Secretory-(1)_24hpi\|(03)_Secretory / shred by cell type and Timepoint	AUNIP PRSS27 KCNK5	5.86e-04	135	54	3	6e473296dfe1ff7a63d701e56920c0a1b043ddc6
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_3\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	MAGEL2 MALRD1 FAM167B	5.99e-04	136	54	3	5e209185b5f6e9347829fc9066f0b2c3711df057
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHA6 TACR3 EPHA5	7.21e-04	145	54	3	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	Bronchus_Control_(B.)-Immune-TX-TRAM-3\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	AUNIP C1orf167 FAM167B	7.50e-04	147	54	3	50a855aa7f214c3be8ac46a22adf9bc9dd0285db
ToppCell	Club_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	MAGED1 KCTD3 KDR	7.50e-04	147	54	3	9211242a8e40d50414d310940616eccce299a7f8
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KLHL1 EPHA6 EPHA5	7.65e-04	148	54	3	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Thalamus / BrainAtlas - Mouse McCarroll V32	MAGEL2 COL19A1 TACR3	7.65e-04	148	54	3	afebb64365c94b9476494bffe7c364677f19c8cf
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	EVC2 CEACAM5 CDH20	7.65e-04	148	54	3	1186ee0d15244fee74c1d09df3967c1b69f8ddce
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MAGEL2 COL19A1 ECE2	7.65e-04	148	54	3	4d43efee96a6493abd78e9ca41aab73db0c80626
ToppCell	Thalamus-Neuronal-Inhibitory\|Thalamus / BrainAtlas - Mouse McCarroll V32	MAGEL2 COL19A1 TACR3	7.65e-04	148	54	3	5f82e5ecacfd223020b8ee975c17d68c1fe6db38
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175\|Adult / Lineage, Cell type, age group and donor	CRYBB3 SFXN2 KCNK5	7.95e-04	150	54	3	b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCell	Bronchial_Biopsy-Epithelial-Goblet_2\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	CEACAM5 NTHL1 KDR	8.42e-04	153	54	3	b25629953ff79aff645845376132b12023067b01
ToppCell	Bronchial_Biopsy-Epithelial-Goblet_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	CEACAM5 NTHL1 KDR	8.42e-04	153	54	3	e9d6b4e895ddb8d6e6c8b043da591ec11365e124
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	MALRD1 TPRG1L KDR	8.58e-04	154	54	3	6c1e7682c43c40b58b371c58deb10b839700ebcc
Drug	Isosorbide dinitrate [87-33-2]; Down 200; 17uM; MCF7; HT_HG-U133A	PER3 SFXN3 TNRC6B CEP97 PGBD5 DCAF7	5.52e-06	196	52	6	6038_DN
Disease	Polyposis, Adenomatous Intestinal	NTHL1 CD44	3.74e-04	16	53	2	C2713442
Disease	Familial Intestinal Polyposis	NTHL1 CD44	3.74e-04	16	53	2	C2713443
Disease	Adenomatous Polyposis Coli	NTHL1 CD44	4.23e-04	17	53	2	C0032580
Disease	borna disease (biomarker_via_orthology)	CD44 DDIT3	4.75e-04	18	53	2	DOID:5154 (biomarker_via_orthology)
Disease	brain age measurement	EEF1AKMT4-ECE2 ECE2	5.89e-04	20	53	2	EFO_0010602
Disease	Large cell carcinoma of lung	EPHA3 EPHA5	1.52e-03	32	53	2	C0345958
Disease	Squamous cell carcinoma of lung	EPHA3 EPHA5	1.52e-03	32	53	2	C0149782
Disease	IGA Glomerulonephritis	MAN2B1 CD44	1.71e-03	34	53	2	C0017661
Disease	colorectal adenocarcinoma (is_implicated_in)	CD44 KDR	1.81e-03	35	53	2	DOID:0050861 (is_implicated_in)
Disease	orofacial cleft	BEST3 EPHA3	2.03e-03	37	53	2	MONDO_0000358
Disease	progression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian serous carcinoma	CD44 EPHA3	2.60e-03	42	53	2	EFO_0004920, EFO_1001516, GO_0097328, MONDO_0009354
Disease	Paroxysmal atrial fibrillation	DNAH10 BEST3 EPHA3	2.80e-03	156	53	3	C0235480
Disease	familial atrial fibrillation	DNAH10 BEST3 EPHA3	2.80e-03	156	53	3	C3468561
Disease	Persistent atrial fibrillation	DNAH10 BEST3 EPHA3	2.80e-03	156	53	3	C2585653
Disease	Atrial Fibrillation	DNAH10 BEST3 EPHA3	3.00e-03	160	53	3	C0004238

Protein segments in the cluster

Peptide	Gene	Start	Entry
VTLVVNRWWNQFVNL	BEST3	86	Q8N1M1
LWQARAQQFQGTARW	C1orf167	886	Q5SNV9
WHTQIQWATQVFQKP	COG7	261	P83436
EPEIQNTTYLWWVNN	CEACAM5	346	P06731
EQNQNNWLLTSWISN	EPHA5	106	P54756
FTNIKQWNVNWETRQ	FERMT1	606	Q9BQL6
QWNVNWETRQVVIEF	FERMT1	611	Q9BQL6
ETQNTTYLWWVNNQS	CEACAM7	171	Q14002
INNVQWASTQPDWIA	DCAF7	316	P61962
AWQNPSGWQNQTARQ	MAGED1	301	Q9Y5V3
QATQQGWQATPLTWQ	MAGEL2	376	Q9UJ55
TTQVTWQAPAVTWQV	MAGEL2	391	Q9UJ55
RWNTFNSLWDQNQAI	ECE2	186	P0DPD6
AQLPFWNNWTQRAAR	PER3	186	P56645
GNQTFNNWNWPNAMI	KCNK5	76	O95279
NNWNWPNAMIFAATV	KCNK5	81	O95279
QKWAVDPQNTAWSND	PINX1	11	Q96BK5
EAAQQQQALASWQQW	EVC2	1036	Q86UK5
SVKWHQGQNQTWNRP	GARIN1B	121	Q96KD3
NTVERWDPQARQWNF	KLHL5	576	Q96PQ7
NPRINQLSARWQQVW	MACF1	6986	Q9UPN3
GVVSIWAQNQVENWS	RBBP5	316	Q15291
WAQNQVENWSAFAPD	RBBP5	321	Q15291
QLWQNPDEQQSQRGW	MYO15B	561	Q96JP2
WQQVFWFAISIAINN	PGBD5	471	Q8N414
IQHLWQNTAALPNQW	MALRD1	171	Q5VYJ5
DINWDSSQWQPLIQD	UPF1	221	Q92900
GWQRQSQNQSWNLRR	DDIT3	6	P0DPQ6
RSRWNTFNSLWDQNQ	EEF1AKMT4-ECE2	256	P0DPD8
DHTKQNQDWTQWNPS	CD44	316	P16070
RWFLWQVLNQQNIPQ	COL19A1	116	Q14993
PQSHQRTKRSWVWNQ	CDH20	51	Q9HBT6
RFLWNQVRSLQVWQQ	CEP97	626	Q8IW35
WNEWDASQPQLQSVR	CRYBB3	181	P26998
KQVLHSWFRQPQSNW	GDF11	241	O95390
SWFRQPQSNWGIEIN	GDF11	246	O95390
SEARQNWPQNWGFLT	C20orf85	31	Q9H1P6
HSQNNWLRTNWVPRN	EPHA3	76	P29320
RWWHQQTNATQEVVR	MAN2B1	126	O00754
AWRQQIQWENNGQVF	LOX	41	P28300
VNDWQNNSTRLWNSQ	HERVK_113	501	Q902F9
WTNQRLNTQITQWVG	EMC9	186	Q9Y3B6
LPDDVENNQTVWQEW	DNAH10	3791	Q8IVF4
QAQVSPQAWHFSWQL	IPO13	51	O94829
GVWNAVTQHWQVQDV	KCTD3	301	Q9Y597
WTAQVQSQAWRRAQA	FAM167B	46	Q9BTA0
NTRAPFQDVTNNWNW	AUNIP	301	Q9H7T9
LDPWENQWNVVAINV	KBTBD12	576	Q3ZCT8
PNQNNWLRTNWISRD	EPHA6	81	Q9UF33
VVFWQWVNQSFNAIV	SFXN3	116	Q9BWM7
VIFWQWVNQSFNALV	SFXN2	116	Q96NB2
VWEPQDWQQQLVNIR	NTHL1	86	P78549
WANLTNQFVQPSWRI	TACR3	71	P29371
PVLNTWKVLQQQWTN	ADGRF5	806	Q8IZF2
TQEGEWPWQVSIQRN	PRSS27	41	Q9BQR3
QWDKQSRPSFINRWN	TPRG1L	166	Q5T0D9
VQWQWDRSQNPFQSV	TAS1R2	451	Q8TE23
WLWPNNQSGSEQRVE	KDR	61	P35968
NLQWFHQNPWGQLIN	TRAV22	51	A0A0B4J277
WNETGRQPNSWNKQH	TNRC6B	806	Q9UPQ9
ERWDPQSQQWTFVAS	KLHL1	571	Q9NR64