Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondisaccharide binding

LGALS9C LGALS9B

5.53e-057332GO:0048030
GeneOntologyMolecularFunctiongalactoside binding

LGALS9C LGALS9B

9.47e-059332GO:0016936
GeneOntologyMolecularFunctionoligosaccharide binding

LGALS9C LGALS9B

4.94e-0420332GO:0070492
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

FASN HSD17B2 ME1

1.19e-03127333GO:0016616
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

FASN HSD17B2 ME1

1.51e-03138333GO:0016614
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A6 COL24A1

2.62e-0346332GO:0030020
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMA4 COL4A6 COL24A1

3.64e-03188333GO:0005201
GeneOntologyMolecularFunctionmanganese ion binding

ADPRM ME1

6.13e-0371332GO:0030145
GeneOntologyMolecularFunctionprotein serine/threonine kinase activator activity

LGALS9C LGALS9B

7.35e-0378332GO:0043539
GeneOntologyBiologicalProcessectodermal placode morphogenesis

TBX3 SIX4 TBX2

2.06e-0616333GO:0071697
GeneOntologyBiologicalProcessectodermal placode formation

TBX3 SIX4 TBX2

2.06e-0616333GO:0060788
GeneOntologyBiologicalProcessectodermal placode development

TBX3 SIX4 TBX2

3.00e-0618333GO:0071696
GeneOntologyBiologicalProcessureteric peristalsis

TBX3 TBX2

7.44e-063332GO:0072105
GeneOntologyBiologicalProcessureter smooth muscle contraction

TBX3 TBX2

7.44e-063332GO:0014849
GeneOntologyBiologicalProcessmammary placode formation

TBX3 TBX2

1.49e-054332GO:0060596
GeneOntologyBiologicalProcessnegative regulation of natural killer cell degranulation

LGALS9C LGALS9B

1.49e-054332GO:0043322
GeneOntologyBiologicalProcessatrioventricular canal morphogenesis

TBX3 TBX2

2.47e-055332GO:1905222
GeneOntologyBiologicalProcesscardiac jelly development

TBX3 TBX2

3.71e-056332GO:1905072
GeneOntologyBiologicalProcessregulation of natural killer cell degranulation

LGALS9C LGALS9B

6.91e-058332GO:0043321
GeneOntologyBiologicalProcessmammary gland formation

TBX3 TBX2

8.87e-059332GO:0060592
GeneOntologyBiologicalProcessheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

LGALS9C ITGA5 LGALS9B

1.39e-0463333GO:0007157
GeneOntologyBiologicalProcessheart looping

TBX3 C2CD3 TBX2

2.15e-0473333GO:0001947
GeneOntologyBiologicalProcessatrioventricular canal development

TBX3 TBX2

2.23e-0414332GO:0036302
GeneOntologyBiologicalProcessembryonic digit morphogenesis

TBX3 C2CD3 TBX2

2.24e-0474333GO:0042733
GeneOntologyBiologicalProcessurinary tract smooth muscle contraction

TBX3 TBX2

2.57e-0415332GO:0014848
GeneOntologyBiologicalProcessnegative regulation of natural killer cell activation

LGALS9C LGALS9B

2.57e-0415332GO:0032815
GeneOntologyBiologicalProcessperistalsis

TBX3 TBX2

2.57e-0415332GO:0030432
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B

2.57e-0415332GO:2000562
GeneOntologyBiologicalProcessdetermination of heart left/right asymmetry

TBX3 C2CD3 TBX2

2.72e-0479333GO:0061371
GeneOntologyBiologicalProcessembryonic heart tube morphogenesis

TBX3 C2CD3 TBX2

2.82e-0480333GO:0003143
GeneOntologyBiologicalProcessregulation of oxidoreductase activity

LGALS9C LGALS9B SZT2

3.25e-0484333GO:0051341
GeneOntologyBiologicalProcessnegative regulation of leukocyte degranulation

LGALS9C LGALS9B

3.33e-0417332GO:0043301
GeneOntologyBiologicalProcessmuscle cell fate commitment

TBX3 TBX2

3.74e-0418332GO:0042693
GeneOntologyBiologicalProcessnatural killer cell degranulation

LGALS9C LGALS9B

3.74e-0418332GO:0043320
GeneOntologyBiologicalProcessnegative regulation of alpha-beta T cell proliferation

LGALS9C LGALS9B

4.17e-0419332GO:0046642
GeneOntologyBiologicalProcesspositive regulation of defense response to bacterium

LGALS9C LGALS9B

4.17e-0419332GO:1900426
GeneOntologyBiologicalProcessregulation of T cell chemotaxis

LGALS9C LGALS9B

4.63e-0420332GO:0010819
GeneOntologyBiologicalProcessregulation of natural killer cell differentiation

LGALS9C LGALS9B

5.11e-0421332GO:0032823
GeneOntologyBiologicalProcessembryonic heart tube development

TBX3 C2CD3 TBX2

5.92e-04103333GO:0035050
GeneOntologyBiologicalProcessregulation of defense response to bacterium

LGALS9C LGALS9B

7.88e-0426332GO:1900424
GeneOntologyBiologicalProcessregulation of CD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B

9.14e-0428332GO:2000561
GeneOntologyBiologicalProcessphasic smooth muscle contraction

TBX3 TBX2

1.05e-0330332GO:0014821
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B

1.05e-0330332GO:0035739
GeneOntologyBiologicalProcessregulation of lymphocyte chemotaxis

LGALS9C LGALS9B

1.12e-0331332GO:1901623
GeneOntologyBiologicalProcesspositive regulation of regulatory T cell differentiation

LGALS9C LGALS9B

1.12e-0331332GO:0045591
GeneOntologyBiologicalProcessinner ear morphogenesis

TBX3 SIX4 TBX2

1.14e-03129333GO:0042472
GeneOntologyBiologicalProcessnegative regulation of regulated secretory pathway

LGALS9C LGALS9B

1.19e-0332332GO:1903306
GeneOntologyBiologicalProcessendocardial cushion formation

TBX3 TBX2

1.19e-0332332GO:0003272
GeneOntologyBiologicalProcessT cell chemotaxis

LGALS9C LGALS9B

1.27e-0333332GO:0010818
GeneOntologyBiologicalProcessmyoblast differentiation

TBX3 CSRP3 TBX2

1.32e-03136333GO:0045445
GeneOntologyBiologicalProcesspharyngeal system development

SIX4 TBX2

1.35e-0334332GO:0060037
GeneOntologyBiologicalProcessnegative regulation of myoblast differentiation

TBX3 CSRP3

1.35e-0334332GO:0045662
GeneOntologyBiologicalProcessregulation of T cell differentiation in thymus

LGALS9C LGALS9B

1.60e-0337332GO:0033081
GeneOntologyBiologicalProcessnatural killer cell differentiation

LGALS9C LGALS9B

1.68e-0338332GO:0001779
GeneOntologyBiologicalProcessembryonic limb morphogenesis

TBX3 C2CD3 TBX2

1.69e-03148333GO:0030326
GeneOntologyBiologicalProcessembryonic appendage morphogenesis

TBX3 C2CD3 TBX2

1.69e-03148333GO:0035113
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated cytotoxicity

LGALS9C LGALS9B

1.86e-0340332GO:0045953
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell activation

LGALS9C LGALS9B

1.86e-0340332GO:2000515
GeneOntologyBiologicalProcessear morphogenesis

TBX3 SIX4 TBX2

1.89e-03154333GO:0042471
GeneOntologyBiologicalProcessdetermination of left/right symmetry

TBX3 C2CD3 TBX2

1.89e-03154333GO:0007368
GeneOntologyBiologicalProcesspositive regulation of T cell migration

LGALS9C LGALS9B

1.96e-0341332GO:2000406
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated immunity

LGALS9C LGALS9B

1.96e-0341332GO:0002716
GeneOntologyBiologicalProcessnatural killer cell activation involved in immune response

LGALS9C LGALS9B

2.05e-0342332GO:0002323
GeneOntologyBiologicalProcesspositive regulation of macrophage activation

LGALS9C LGALS9B

2.05e-0342332GO:0043032
GeneOntologyBiologicalProcesspositive regulation of SMAD protein signal transduction

LGALS9C LGALS9B

2.15e-0343332GO:0060391
GeneOntologyBiologicalProcessleft/right pattern formation

TBX3 C2CD3 TBX2

2.18e-03162333GO:0060972
GeneOntologyBiologicalProcessmammary gland development

TBX3 FASN TBX2

2.18e-03162333GO:0030879
GeneOntologyBiologicalProcessendocardial cushion morphogenesis

TBX3 TBX2

2.25e-0344332GO:0003203
GeneOntologyBiologicalProcessembryonic organ morphogenesis

TBX3 C2CD3 SIX4 TBX2

2.28e-03351334GO:0048562
GeneOntologyBiologicalProcessdetermination of bilateral symmetry

TBX3 C2CD3 TBX2

2.30e-03165333GO:0009855
GeneOntologyBiologicalProcessspecification of symmetry

TBX3 C2CD3 TBX2

2.30e-03165333GO:0009799
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

LGALS9C COL4A6 ITGA5 LGALS9B CSRP3 AKAP7 TBX2

2.33e-031186337GO:0007167
GeneOntologyBiologicalProcessnegative regulation of exocytosis

LGALS9C LGALS9B

2.35e-0345332GO:0045920
GeneOntologyBiologicalProcesspositive regulation of oxidoreductase activity

LGALS9C LGALS9B

2.46e-0346332GO:0051353
GeneOntologyBiologicalProcessnegative regulation of leukocyte mediated cytotoxicity

LGALS9C LGALS9B

2.57e-0347332GO:0001911
GeneOntologyBiologicalProcessregulation of T-helper 17 type immune response

LGALS9C LGALS9B

2.57e-0347332GO:2000316
GeneOntologyBiologicalProcesspositive regulation of interleukin-10 production

LGALS9C LGALS9B

2.67e-0348332GO:0032733
GeneOntologyBiologicalProcesshemopoiesis

LGALS9C DDIAS COL24A1 FASN TMEM190 LGALS9B GPS2

2.78e-031223337GO:0030097
GeneOntologyBiologicalProcesspositive regulation of lymphocyte migration

LGALS9C LGALS9B

2.79e-0349332GO:2000403
GeneOntologyBiologicalProcessregulation of regulatory T cell differentiation

LGALS9C LGALS9B

2.79e-0349332GO:0045589
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

TBX3 C2CD3 SIX4 ITGA5 TBX2

2.83e-03619335GO:0002009
GeneOntologyBiologicalProcesspositive regulation of leukocyte migration

LGALS9C TNFRSF18 LGALS9B

2.90e-03179333GO:0002687
GeneOntologyBiologicalProcessnegative regulation of type II interferon production

LGALS9C LGALS9B

3.01e-0351332GO:0032689
GeneOntologyBiologicalProcessnegative regulation of cell killing

LGALS9C LGALS9B

3.13e-0352332GO:0031342
GeneOntologyBiologicalProcessnegative regulation of alpha-beta T cell activation

LGALS9C LGALS9B

3.13e-0352332GO:0046636
GeneOntologyBiologicalProcessembryonic axis specification

TBX3 C2CD3

3.13e-0352332GO:0000578
GeneOntologyBiologicalProcessappendage morphogenesis

TBX3 C2CD3 TBX2

3.18e-03185333GO:0035107
GeneOntologyBiologicalProcesslimb morphogenesis

TBX3 C2CD3 TBX2

3.18e-03185333GO:0035108
GeneOntologyBiologicalProcesslymphocyte chemotaxis

LGALS9C LGALS9B

3.25e-0353332GO:0048247
GeneOntologyBiologicalProcessregulation of alpha-beta T cell proliferation

LGALS9C LGALS9B

3.25e-0353332GO:0046640
GeneOntologyBiologicalProcessregulatory T cell differentiation

LGALS9C LGALS9B

3.37e-0354332GO:0045066
GeneOntologyBiologicalProcessregulation of T cell migration

LGALS9C LGALS9B

3.62e-0356332GO:2000404
Domain-

LGALS9C LAMA4 COL24A1 LMAN2L LGALS9B

5.53e-07953252.60.120.200
DomainTBX

TBX3 TBX2

2.84e-062322IPR022582
DomainTBX

TBX3 TBX2

2.84e-062322PF12598
DomainConA-like_dom

LGALS9C LAMA4 COL24A1 LMAN2L LGALS9B

3.29e-05219325IPR013320
DomainGal-bind_lectin

LGALS9C LGALS9B

2.94e-0415322SM00908
DomainGALECTIN

LGALS9C LGALS9B

2.94e-0415322PS51304
DomainGalectin_CRD

LGALS9C LGALS9B

2.94e-0415322IPR001079
DomainGal-bind_lectin

LGALS9C LGALS9B

2.94e-0415322PF00337
DomainGLECT

LGALS9C LGALS9B

2.94e-0415322SM00276
DomainTF_T-box

TBX3 TBX2

3.81e-0417322IPR001699
DomainTBOX_3

TBX3 TBX2

3.81e-0417322PS50252
DomainTBOX

TBX3 TBX2

3.81e-0417322SM00425
DomainTF_T-box_CS

TBX3 TBX2

3.81e-0417322IPR018186
DomainT-box

TBX3 TBX2

3.81e-0417322PF00907
Domain-

TBX3 TBX2

3.81e-04173222.60.40.820
DomainTBOX_1

TBX3 TBX2

3.81e-0417322PS01283
DomainTBOX_2

TBX3 TBX2

3.81e-0417322PS01264
DomainLAM_G_DOMAIN

LAMA4 COL24A1

1.92e-0338322PS50025
DomainLaminin_G_2

LAMA4 COL24A1

2.13e-0340322PF02210
Domain-

FASN HSD17B2 ME1

2.98e-031693233.40.50.720
DomainNAD(P)-bd_dom

FASN HSD17B2 ME1

3.18e-03173323IPR016040
Domainp53-like_TF_DNA-bd

TBX3 TBX2

3.71e-0353322IPR008967
Domainadh_short

FASN HSD17B2

3.99e-0355322PF00106
DomainLaminin_G

LAMA4 COL24A1

4.43e-0358322IPR001791
Pubmed

Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence.

TBX3 RBL2 TBX2

7.77e-09533322002537
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

LGALS9C LAMA4 COL4A6 COL24A1 LGALS9B

6.45e-0717533528071719
Pubmed

Complex functional redundancy of Tbx2 and Tbx3 in mouse limb development.

TBX3 TBX2

8.73e-07233235506352
Pubmed

The T-box transcription factors TBX2 and TBX3 in mammary gland development and breast cancer.

TBX3 TBX2

8.73e-07233223624936
Pubmed

The transcription factors TBX2 and TBX3 interact with human papillomavirus 16 (HPV16) L2 and repress the long control region of HPVs.

TBX3 TBX2

8.73e-07233223388722
Pubmed

Identification of TBX2 and TBX3 variants in patients with conotruncal heart defects by target sequencing.

TBX3 TBX2

8.73e-07233230223900
Pubmed

Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome.

TBX3 TBX2

8.73e-07233210468588
Pubmed

Stratification based on methylation of TBX2 and TBX3 into three molecular grades predicts progression in patients with pTa-bladder cancer.

TBX3 TBX2

8.73e-07233225394776
Pubmed

The anti-proliferative function of the TGF-β1 signaling pathway involves the repression of the oncogenic TBX2 by its homologue TBX3.

TBX3 TBX2

8.73e-07233225371204
Pubmed

Crystal structure of the galectin-9 N-terminal carbohydrate recognition domain from Mus musculus reveals the basic mechanism of carbohydrate recognition.

LGALS9C LGALS9B

2.62e-06333216990264
Pubmed

Galectin-9 Is Critical for Mucosal Adaptive Immunity through the T Helper 17-IgA Axis.

LGALS9C LGALS9B

2.62e-06333229458010
Pubmed

Expression of Drosophila omb-related T-box genes in the developing human and mouse neural retina.

TBX3 TBX2

2.62e-06333211726608
Pubmed

Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue.

LGALS9C LGALS9B

2.62e-06333218005988
Pubmed

Galectin-9 ameliorates clinical severity of MRL/lpr lupus-prone mice by inducing plasma cell apoptosis independently of Tim-3.

LGALS9C LGALS9B

2.62e-06333223585851
Pubmed

Galectin-9 ameliorates anti-GBM glomerulonephritis by inhibiting Th1 and Th17 immune responses in mice.

LGALS9C LGALS9B

2.62e-06333224477688
Pubmed

Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation.

LGALS9C LGALS9B

2.62e-06333219776007
Pubmed

A unique role for galectin-9 in angiogenesis and inflammatory arthritis.

LGALS9C LGALS9B

2.62e-06333229433546
Pubmed

Cooperative Interactions of Oligosaccharide and Peptide Moieties of a Glycopeptide Derived from IgE with Galectin-9.

LGALS9C LGALS9B

2.62e-06333226582205
Pubmed

Oncogenic miR-93-5p/Gal-9 axis drives CD8 (+) T-cell inactivation and is a therapeutic target for hepatocellular carcinoma immunotherapy.

LGALS9C LGALS9B

2.62e-06333237105392
Pubmed

Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.

LGALS9C LGALS9B

2.62e-0633329153289
Pubmed

Galectin-9 regulates follicular helper T cells to inhibit humoral autoimmunity-induced pulmonary fibrosis.

LGALS9C LGALS9B

2.62e-06333233316546
Pubmed

Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice.

LGALS9C LGALS9B

2.62e-06333218974023
Pubmed

T-box family reunion.

TBX3 TBX2

2.62e-0633329196325
Pubmed

Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin.

LGALS9C LGALS9B

2.62e-0633329038233
Pubmed

Cell surface galectin-9 expressing Th cells regulate Th17 and Foxp3+ Treg development by galectin-9 secretion.

LGALS9C LGALS9B

2.62e-06333223144904
Pubmed

Impaired Gal-9 Dysregulates the PBMC-Induced Th1/Th2 Imbalance in Abortion-Prone Matings.

LGALS9C LGALS9B

2.62e-06333229651447
Pubmed

Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.

LGALS9C LGALS9B

2.62e-06333236479526
Pubmed

Protective effect of Galectin-9 in murine model of lung emphysema: Involvement of neutrophil migration and MMP-9 production.

LGALS9C LGALS9B

2.62e-06333228704475
Pubmed

The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity.

LGALS9C LGALS9B

2.62e-06333221146220
Pubmed

Profiling Lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological human pregnancy.

LGALS9C LGALS9B

2.62e-06333223242525
Pubmed

Galectin-9 in allergic airway inflammation and hyper-responsiveness in mice.

LGALS9C LGALS9B

2.62e-06333219851072
Pubmed

The Role of Galectin-9 as Mediator of Atopic Dermatitis: Effect on Keratinocytes.

LGALS9C LGALS9B

2.62e-06333233923930
Pubmed

Alarmin function of galectin-9 in murine respiratory tularemia.

LGALS9C LGALS9B

2.62e-06333225898318
Pubmed

Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells.

LGALS9C LGALS9B

2.62e-06333231937306
Pubmed

Molecular mechanisms of pituitary organogenesis: In search of novel regulatory genes.

TBX3 TBX2

2.62e-06333220025935
Pubmed

Intestinal epithelial cells express galectin-9 in patients with food allergy that plays a critical role in sustaining allergic status in mouse intestine.

LGALS9C LGALS9B

2.62e-06333221426359
Pubmed

Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases.

LGALS9C LGALS9B

2.62e-06333231969388
Pubmed

Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.

LGALS9C LGALS9B

2.62e-06333223836896
Pubmed

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis.

LGALS9C LGALS9B

2.62e-06333218282810
Pubmed

Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family.

TBX3 TBX2

2.62e-0633328988164
Pubmed

Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.

LGALS9C LGALS9B

2.62e-06333235241678
Pubmed

Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes.

LGALS9C LGALS9B

2.62e-0633327890611
Pubmed

The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator.

TBX3 TBX2

2.62e-06333212000749
Pubmed

Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner.

LGALS9C LGALS9B

2.62e-06333222341088
Pubmed

Regulation of M1‑type and M2‑type macrophage polarization in RAW264.7 cells by Galectin‑9.

LGALS9C LGALS9B

2.62e-06333228990062
Pubmed

Galectin-9 Is a Novel Regulator of Epithelial Restitution.

LGALS9C LGALS9B

2.62e-06333232380082
Pubmed

Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.

LGALS9C LGALS9B

2.62e-06333224083426
Pubmed

Galectin-9-mediated protection from allo-specific T cells as a mechanism of immune privilege of corneal allografts.

LGALS9C LGALS9B

2.62e-06333223667648
Pubmed

Galectin-9 in synergy with NF-κB inhibition restores immune regulatory capability in dendritic cells of subjects with food allergy.

LGALS9C LGALS9B

2.62e-06333237279535
Pubmed

Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices.

LGALS9C LGALS9B

2.62e-06333218579572
Pubmed

The protective function of galectin-9 in liver ischemia and reperfusion injury in mice.

LGALS9C LGALS9B

2.62e-06333225931247
Pubmed

Possible regulatory role of galectin-9 on Ascaris suum-induced eosinophilic lung inflammation in mice.

LGALS9C LGALS9B

2.62e-06333222627368
Pubmed

Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9.

LGALS9C LGALS9B

2.62e-06333228877989
Pubmed

Galectin-9 is required for endometrial regenerative cells to induce long-term cardiac allograft survival in mice.

LGALS9C LGALS9B

2.62e-06333233153471
Pubmed

Galectin-9 ameliorates immune complex-induced arthritis by regulating Fc gamma R expression on macrophages.

LGALS9C LGALS9B

2.62e-06333219800850
Pubmed

T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses.

LGALS9C LGALS9B

2.62e-06333222052881
Pubmed

TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence.

TBX3 TBX2

2.62e-06333211748239
Pubmed

Galectin-9 protects mice from the Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes.

LGALS9C LGALS9B

2.62e-06333217560833
Pubmed

The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy.

LGALS9C LGALS9B

2.62e-06333238987795
Pubmed

Galectin-9 supports primary T cell transendothelial migration in a glycan and integrin dependent manner.

LGALS9C LGALS9B

2.62e-06333235643073
Pubmed

Galectin-9 functionally impairs natural killer cells in humans and mice.

LGALS9C LGALS9B

2.62e-06333223408620
Pubmed

Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response.

LGALS9C LGALS9B

5.23e-06433220463811
Pubmed

SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.

LGALS9C LGALS9B

5.23e-06433238686388
Pubmed

Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells.

LGALS9C LGALS9B

5.23e-06433222677125
Pubmed

Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas.

LGALS9C LGALS9B

5.23e-06433232855403
Pubmed

Galectin-3 mediates oligomerization of secreted hensin using its carbohydrate-recognition domain.

LGALS9C LGALS9B

5.23e-06433223657851
Pubmed

Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.

LGALS9C LGALS9B

5.23e-06433219234217
Pubmed

Tbx3 represses E-cadherin expression and enhances melanoma invasiveness.

TBX3 TBX2

5.23e-06433218829543
Pubmed

[Expression and significance of galectin-3 and galectin-9 in mice nasal mucosa with allergic rhinitis].

LGALS9C LGALS9B

5.23e-06433218826117
Pubmed

The Tim-3/galectin-9 pathway involves in the homeostasis of hepatic Tregs in a mouse model of concanavalin A-induced hepatitis.

LGALS9C LGALS9B

5.23e-06433224333756
Pubmed

The expression of Galectin-9 correlates with mTOR and AMPK in murine colony-forming erythroid progenitors.

LGALS9C LGALS9B

5.23e-06433238853593
Pubmed

Tim-3/Galectin-9 signaling pathway is involved in the cytokine changes in mice with alveolar echinococcosis.

LGALS9C LGALS9B

5.23e-06433235715604
Pubmed

Genome-wide analysis of CpG island methylation in bladder cancer identified TBX2, TBX3, GATA2, and ZIC4 as pTa-specific prognostic markers.

TBX3 TBX2

5.23e-06433222284968
Pubmed

Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies.

LGALS9C LGALS9B

5.23e-06433224958847
Pubmed

Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions.

LGALS9C LGALS9B

5.23e-06433219017954
Pubmed

Evidence of a role for T-box genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity.

TBX3 TBX2

5.23e-0643328798150
Pubmed

Galectin-9 binds IgM-BCR to regulate B cell signaling.

LGALS9C LGALS9B

5.23e-06433230120235
Pubmed

Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.

LGALS9C LGALS9B

5.23e-06433233963043
Pubmed

Galectin-9: A novel promoter of atherosclerosis progression.

LGALS9C LGALS9B

5.23e-06433236459823
Pubmed

[Expression of Galectin-9 and Tim-3 in lungs of mice with asthma].

LGALS9C LGALS9B

5.23e-06433221575348
Pubmed

Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts.

LGALS9C LGALS9B

5.23e-06433218346632
Pubmed

Isolation and characterization of a novel eosinophil-specific galectin released into the lungs in response to allergen challenge.

LGALS9C LGALS9B

5.23e-06433211839756
Pubmed

Newly characterized decidual Tim-3+ Treg cells are abundant during early pregnancy and driven by IL-27 coordinately with Gal-9 from trophoblasts.

LGALS9C LGALS9B

5.23e-06433233107565
Pubmed

Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice.

LGALS9C LGALS9B

5.23e-06433219670381
Pubmed

Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models.

LGALS9C LGALS9B

5.23e-06433229611821
Pubmed

Lipopolysaccharide mediates time-dependent macrophage M1/M2 polarization through the Tim-3/Galectin-9 signalling pathway.

LGALS9C LGALS9B

5.23e-06433230763585
Pubmed

Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury.

LGALS9C LGALS9B

5.23e-06433225450716
Pubmed

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity.

LGALS9C LGALS9B

5.23e-06433216286920
Pubmed

Galectin-9 regulates the threshold of B cell activation and autoimmunity.

LGALS9C LGALS9B

5.23e-06433234369876
Pubmed

Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2.

LGALS9C LGALS9B

5.23e-06433233727589
Pubmed

Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells.

LGALS9C LGALS9B

5.23e-06433219362679
Pubmed

Targeting the CD146/Galectin-9 axis protects the integrity of the blood-brain barrier in experimental cerebral malaria.

LGALS9C LGALS9B

5.23e-06433233203936
Pubmed

The Galectin-9/Tim-3 pathway is involved in the regulation of NK cell function at the maternal-fetal interface in early pregnancy.

LGALS9C LGALS9B

5.23e-06433225578313
Pubmed

Intestinal Lamina Propria CD4+ T Cells Promote Bactericidal Activity of Macrophages via Galectin-9 and Tim-3 Interaction during Salmonella enterica Serovar Typhimurium Infection.

LGALS9C LGALS9B

5.23e-06433229844236
Pubmed

Influence of galectin-9/Tim-3 interaction on herpes simplex virus-1 latency.

LGALS9C LGALS9B

5.23e-06433222021615
Pubmed

Embryonic implantation in galectin 1/galectin 3 double mutant mice.

LGALS9C LGALS9B

8.72e-0653329566950
Pubmed

Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.

LGALS9C LGALS9B

8.72e-06533229242193
Pubmed

Tim-3 signaling in peripheral NK cells promotes maternal-fetal immune tolerance and alleviates pregnancy loss.

LGALS9C LGALS9B

8.72e-06533228951537
Pubmed

Feto-maternal immune regulation by TIM-3/galectin-9 pathway and PD-1 molecule in mice at day 14.5 of pregnancy.

LGALS9C LGALS9B

8.72e-06533226278059
Pubmed

The level of BMP4 signaling is critical for the regulation of distinct T-box gene expression domains and growth along the dorso-ventral axis of the optic cup.

TBX3 TBX2

8.72e-06533217173667
CytobandEnsembl 112 genes in cytogenetic band chr16q23

HSD17B2 OSGIN1

3.18e-03116332chr16q23
GeneFamilyGalectins

LGALS9C LGALS9B

1.34e-0415212629
GeneFamilyT-boxes

TBX3 TBX2

1.94e-0418212766
GeneFamilyCollagens

COL4A6 COL24A1

1.29e-0346212490
GeneFamilyShort chain dehydrogenase/reductase superfamily

FASN HSD17B2

3.48e-0376212743
CoexpressionGSE42021_TCONV_PLN_VS_CD24LO_TCONV_THYMUS_UP

LAMA4 MAP3K11 HSD17B2 ME1 RBL2

4.91e-06200335M9605
CoexpressionGSE14308_NAIVE_CD4_TCELL_VS_NATURAL_TREG_DN

RBM12 SLC2A9 RBL2 AKAP7

1.13e-04200334M3394
CoexpressionGSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDC_UP

LAMA4 FASN MCMBP RBL2

1.13e-04200334M3774
CoexpressionGSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN

DDIAS ADPRM AKAP7 DNPEP

1.13e-04200334M6249
CoexpressionGSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_UP

MAP3K11 TNFRSF18 HSD17B2 SLC2A9

1.13e-04200334M4370
CoexpressionRUAN_RESPONSE_TO_TNF_DN

LAMA4 FASN ME1

1.35e-0479333M1555
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP

LGALS9C TNFRSF18 LGALS9B RBL2 OSGIN1 TBX2

1.39e-04647336MM981
CoexpressionRUAN_RESPONSE_TO_TNF_DN

LAMA4 FASN ME1

1.45e-0481333MM1175
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A6 TBX3 HSD17B2 ASIC2 AKAP7

3.05e-07194335735eee6ef25589f935fa922788ebbdbfef61249e
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA4 COL24A1 TBX3 TMEM190 TBX2

3.12e-07195335f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL24A1 TBX3 ASIC2 TBX2

5.40e-06157334b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL24A1 TBX3 ME1 TBX2

9.67e-06182334ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellMild-NK|World / Disease group and Cell class

LGALS9C COL24A1 TNFRSF18 LGALS9B

1.03e-051853340565b7c464e1a09e596f5a0b363d2dc9b55c3c50
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA4 COL4A6 TBX3 HSD17B2

1.05e-05186334360c3e9e5c3a943e68e6939b4a47821bfc75b553
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA4 COL4A6 TBX3 AKAP7

1.29e-051963341f47916c2663bd88c1e7c19c6a7688f4c7173ad2
ToppCellPCW_07-8.5-Mesenchymal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA4 COL24A1 TBX3 TBX2

1.29e-051963348e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A6 TBX3 HSD17B2 AKAP7

1.29e-051963341bcae4e0a244af822e2b12b2026a2771316f107d
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA4 COL24A1 TBX3 TBX2

1.32e-0519733444673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA4 COL4A6 TBX3 HSD17B2

1.32e-05197334ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A6 TBX3 HSD17B2 AKAP7

1.35e-05198334447d7182edb2cd8a72ebd3c0d16bc6e4ddcaaa5c
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA4 COL4A6 TBX3 HSD17B2

1.37e-05199334ec74ff85d6b61013b1f785b2fca343759feb7843
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA4 COL24A1 TBX3 TBX2

1.40e-05200334fb53be20392a8309a7393774c774a1b1aec6e676
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

COL4A6 DDIAS OSGIN1

9.76e-051213335035e071033cb76a7fc0128716755b14821e8f05
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

COL4A6 DDIAS OSGIN1

9.76e-05121333c96115bd33455296378a257583b49442d00b39ca
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_P2ry12|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL24A1 ITGA5 HSD17B2

1.23e-0413133380630812f8894b9358d36dc2dd03fea7ee870502
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A6 TBX3 TBX2

1.95e-041533331524557514668f515ac1bbe847611f564b265b42
ToppCellmild_COVID-19_(asymptomatic)-MAIT|World / disease group, cell group and cell class (v2)

FAM227B MORN1 ME1

1.95e-041533332b4c69f6db17927d6506a645ac058133e60b0103
ToppCellmild_COVID-19_(asymptomatic)-MAIT|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

FAM227B MORN1 ME1

1.95e-0415333326852f3d8f80e102e24bcb90e24aac26fdc9a32c
ToppCellAdult-Immune-B_cell-D122|Adult / Lineage, Cell type, age group and donor

DDIAS COL24A1 TNFRSF18

2.03e-041553335857aebd43b901fc9f8c46f2d628582969db9e6a
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FASN ME1 OSGIN1

2.15e-041583339f58428f70d1427b20122c5c1cc7bf521d0f4832
ToppCellsevere_COVID-19-NK_CD56bright|severe_COVID-19 / disease group, cell group and cell class (v2)

LGALS9C COL24A1 TNFRSF18

2.15e-04158333c2e8d96fc29aa2388b92b4fd81d2726e1f7a053f
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FASN ME1 OSGIN1

2.23e-04160333c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

LAMA4 COL4A6 TBX3

2.23e-04160333d783d29150033e9181c0e30870070268fed3fd85
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LGALS9C TNFRSF18 LGALS9B

2.31e-041623339b1c07f0af657095379380c39d763cab0ad73e74
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LMAN2L TMEM190 MORN1

2.39e-041643339e16e52f5a634585f26021bcce9b5d5992ff6db0
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FASN ME1 OSGIN1

2.57e-04168333b98af4043dfa5dfa4413e482879fad88de484675
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FASN ME1 OSGIN1

2.57e-04168333073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCell-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

LAMA4 TNFRSF18 TBX2

2.61e-041693338ebe9a88111c53a09c25a7b6a164a0a17880458d
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FASN ME1 OSGIN1

2.61e-04169333f195467438c589f87224bde7da720dea072d110c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA4 TMEM190 TBX2

2.61e-041693336ff1172da690ca17f7108f1617b255b766971a57
ToppCelldroplet-Liver-HEPATOCYTES-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FASN ME1 OSGIN1

2.61e-041693337785cab967a33560830c394c918d6ce625103858
ToppCellileum|World / shred on tissue and cell subclass

TBX3 OSGIN1 DNPEP

2.66e-041703339f1211bd4287620e19a59f21e6ecdca3e42e0260
ToppCellAdult-Immune-B_cell-D175|Adult / Lineage, Cell type, age group and donor

DDIAS COL24A1 TNFRSF18

2.71e-04171333355a246f3395900342d400f6f7c6640cba0d4d5d
ToppCell3'-Adult-Distal_Rectal-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGALS9C HSD17B2 LGALS9B

2.71e-04171333317b70d72a4ca5336cfb6a49dc57f8e2a8a1c736
ToppCelldroplet-Tongue-nan-24m-Epithelial-suprabasal_interpapillary|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSD17B2 ME1 OSGIN1

2.75e-041723336ece9bb9f31685c918ca4cb7b82cf6ad1cad48af
ToppCellControl-Stromal-Pericyte|World / Disease state, Lineage and Cell class

LAMA4 TBX3 TBX2

2.75e-04172333813d4256b05b66ca11b08cc0026459d79f12c0eb
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A6 COL24A1 TBX2

2.80e-041733331f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCellCOVID-19_Moderate-NK_CD56bright|COVID-19_Moderate / disease group, cell group and cell class

LGALS9C TNFRSF18 LGALS9B

2.80e-04173333a07dcb1e555caaa2235aec219334fcbf2d07f10c
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFRSF18 CSRP3 AKAP7

2.80e-04173333a5b6c3d58f7a8e533330798b81496009a31548af
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFRSF18 CSRP3 AKAP7

2.80e-04173333cc094992b8027f4cef38f0fb0b76f0d07210d1e2
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL24A1 TNFRSF18 RBL2

2.85e-04174333ccc79febfcf588d8294ffc712338be96de8a5033
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

LGALS9C HSD17B2 LGALS9B

2.85e-041743337d2f802f493f19a068e097b2909a9000e2160266
ToppCellControl-Stromal-Pericyte|Control / Disease state, Lineage and Cell class

LAMA4 TBX3 TBX2

2.85e-0417433391fc1f1c891f105a91968c22e2de5321c52b439a
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL24A1 TBX3 TBX2

2.90e-041753331799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.6.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNFRSF18 LMAN2L LGALS9B

2.90e-04175333baaffc9af61f12168d6f7b96eb0b6e98a44a3909
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FASN ME1 OSGIN1

2.90e-041753335c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCellPericytes-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

LAMA4 COL4A6 TBX3

2.90e-04175333ddf721023a7afc8085c5de17aa254a6575444c0f
ToppCellAdult-Immune-B_cell|Adult / Lineage, Cell type, age group and donor

DDIAS COL24A1 TNFRSF18

2.95e-041763334aa00dcde907ad83d3aa4bb10439b7b5c4be1e5d
ToppCelldroplet-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA4 ITGA5 OSGIN1

2.99e-04177333a5b54792ef948a1e1de66301a60e051250189f59
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DDIAS C2CD3 ITGA5

2.99e-041773331921226196b2ab7919d9f843e60d9f4bd9ec9c57
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA4 COL4A6 TBX2

3.04e-041783338ec2a25dda96c9cc9c2904b6cb18f75a293f4969
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA4 COL4A6 TBX2

3.04e-041783336c91331196696e0cf239d105f458e3230659fa38
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

LGALS9C HSD17B2 LGALS9B

3.09e-041793331fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCellStriatum-Endothelial-MURAL|Striatum / BrainAtlas - Mouse McCarroll V32

LAMA4 TBX3 TBX2

3.09e-041793333d58babf44e47462c3d4129dd2e94a2339fd7ce0
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)|Striatum / BrainAtlas - Mouse McCarroll V32

LAMA4 TBX3 TBX2

3.09e-0417933399167ac678cae5c35b1d4f4a81b32000437c00c2
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA4 COL24A1 TBX2

3.15e-04180333f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCellRA-11._Adipocyte|RA / Chamber and Cluster_Paper

LAMA4 FASN ME1

3.15e-04180333d48a3d27357f7d184132a6805950f93080146b59
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

TBX3 ITGA5 TBX2

3.15e-04180333b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL24A1 TBX3 TBX2

3.15e-0418033301f2e5d96016823482f89ba503d007d4bd88eeac
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c03-MKI67|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LGALS9C LGALS9B CSRP3

3.15e-041803331c1b25f1d22518db5469707131510daae84716a3
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL4A6 TBX3 TBX2

3.20e-0418133325915e2500430a902db37d79a749ce2990b69810
ToppCell-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

LAMA4 TNFRSF18 ASIC2

3.20e-04181333ef579e958f334da0f9415aa7e3d5c02c807954a6
ToppCelldroplet-Liver-LIVER-NPC-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSD17B2 ME1 CSRP3

3.20e-041813330a44781cc34535f061812d1370f748b7bbdef17b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA4 TMEM190 TBX2

3.20e-041813336d1f1ad35778a2a227f966f11f6edd8e89452576
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL24A1 TBX3 TBX2

3.20e-04181333d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TNFRSF18 SIX4 LGALS9B

3.20e-041813339c4f9abb9335da2b07644bca8faff1baa1bb9f5b
ToppCelldroplet-Liver-LIVER-NPC-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSD17B2 ME1 CSRP3

3.20e-0418133348d28eafbb5f4b141deeb0bf020dfca39e7be7a5
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL24A1 TNFRSF18 ITGA5

3.25e-04182333b86690c109cdc16844a6cd2216c1bf2bf28efd45
ToppCellLA-11._Adipocyte|World / Chamber and Cluster_Paper

LAMA4 FASN ME1

3.30e-04183333b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCellNS-critical-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LAMA4 ASIC2 AKAP7

3.30e-04183333ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

LAMA4 FASN ME1

3.30e-041833333f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBX3 SLC2A9 TBX2

3.30e-041833333ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCellPericytes-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

LAMA4 TBX3 TBX2

3.35e-04184333cd10d351d91a81dd6dc806cb4e0c8d7861c98e0b
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIX4 HSD17B2 TBX2

3.35e-04184333382b1e90b3f437af596750669c0465a169d97095
ToppCellcritical-Epithelial-Ionocyte|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LAMA4 ASIC2 AKAP7

3.35e-0418433358d36577eff814d46d72f031f3533d71549e3d6e
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL24A1 TBX3 TBX2

3.41e-041853333b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_bright-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LGALS9C TNFRSF18 LGALS9B

3.41e-041853333b2da51aec057b462749ae39afb8f253afcf38d5
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

TBX3 ITGA5 TBX2

3.46e-04186333c6075fe84226b370c5139066793844ad33ae2db1
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LGALS9C TNFRSF18 LGALS9B

3.46e-041863335ad37549592eab23f166196ebf0cb9c8ddf26082
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|356C / Donor, Lineage, Cell class and subclass (all cells)

LAMA4 TBX3 TBX2

3.46e-04186333f0b78c7ee20279970ea8961bf59acb5262f2dce5
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LGALS9C TNFRSF18 LGALS9B

3.46e-04186333c984e5729958237b101df96d1c89a236faacded6
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|356C / Donor, Lineage, Cell class and subclass (all cells)

LAMA4 TBX3 TBX2

3.46e-041863332b3c814a7dee8286ea113c63dc3de5daf0257d37
ToppCell10x5'-Lung-Lymphocytic_Invariant-Inducer-like-ILC3|Lung / Manually curated celltypes from each tissue

FAM227B ADPRM LMAN2L

3.52e-041873330e7aa481effdd8c2fbdf8b65852821dec2d92cde
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSD17B2 OSGIN1 TBX2

3.52e-04187333aa336fb568a24e12c0454265ddd71ed10a6614cf
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

LAMA4 TBX3 TBX2

3.52e-0418733362759efb660179402fb574ce5701c89a2e17bcfe
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA4 COL4A6 HSD17B2

3.52e-0418733339756ab418267151d86f9c2553db859f71900bb1
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL24A1 TBX3 TBX2

3.52e-04187333c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

LAMA4 COL24A1 TBX2

3.52e-04187333bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellfacs-Bladder|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX3 ME1 TBX2

3.52e-04187333dd5ca59417fd1b388fd975f0f3e1f3245d66ebc5
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA4 COL24A1 TBX2

3.52e-04187333a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA4 COL4A6 TBX2

3.57e-04188333997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellRA-11._Adipocyte|World / Chamber and Cluster_Paper

LAMA4 FASN ME1

3.57e-041883334dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCellmoderate-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LAMA4 ASIC2 AKAP7

3.63e-041893336011b747e27d61d222380a7bffdd921a68e9b657
ToppCellStriatum-Endothelial|Striatum / BrainAtlas - Mouse McCarroll V32

LAMA4 TBX3 TBX2

3.63e-0418933395ee3b6d7fbbfcf91c780dfcd0926acec05f0a2d
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

COL24A1 TBX3 TBX2

3.63e-0418933344e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellmoderate-Lymphoid-NK|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LAMA4 TBX3 TBX2

3.63e-0418933322a19365782003c18ec8dddcdbfdaa82c4e330f6
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LGALS9C TNFRSF18 LGALS9B

3.63e-041893333e148accffc6ab249fb0dff7f3bf5a7fff9da773
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL24A1 TBX3 TBX2

3.68e-04190333d24af6af3271e34afab744352afd28be8a7cc5c3
ComputationalGenes in the cancer module 286

FASN HSD17B2 ME1

5.53e-0537223MODULE_286
DiseasePrimary familial dilated cardiomyopathy

LAMA4 CSRP3

4.27e-0430302cv:C0340427
DiseasePrimary dilated cardiomyopathy

LAMA4 CSRP3

5.49e-0434302cv:C0007193
DiseaseFamilial dilated cardiomyopathy

LAMA4 CSRP3

9.21e-0444302C0340427
Diseasefolic acid measurement

MORN1 ASIC2

1.01e-0346302EFO_0005111
DiseaseCardiomyopathy

LAMA4 CSRP3

1.05e-0347302cv:C0878544
Diseaseocular hypertension, response to triamcinolone acetonide

COL24A1 SLC2A9

1.14e-0349302EFO_0006954, EFO_1001069
Diseasesusceptibility to bacterial meningitis measurement

FAM227B AKAP7

1.28e-0352302EFO_0008411
Diseasemosquito bite reaction size measurement

FASN ASIC2 CSRP3

1.29e-03212303EFO_0008378
Diseasebasophil count, eosinophil count

MAP3K11 CSRP3 DNPEP

1.86e-03241303EFO_0004842, EFO_0005090
Diseasecancer (implicated_via_orthology)

TBX3 RBL2 TBX2

2.51e-03268303DOID:162 (implicated_via_orthology)
Diseaseintellectual disability (implicated_via_orthology)

ITGA5 RBL2

2.65e-0375302DOID:1059 (implicated_via_orthology)
Diseasethyroxine measurement

LAMA4 ASIC2

3.23e-0383302EFO_0005130
Diseasecalcium measurement

LMAN2L ASIC2 OSGIN1 TBX2

3.59e-03628304EFO_0004838
DiseaseAbortion, Tubal

LAMA4 COL4A6

5.50e-03109302C0000822
DiseaseEarly Pregnancy Loss

LAMA4 COL4A6

5.50e-03109302C3830362
DiseaseMiscarriage

LAMA4 COL4A6

5.50e-03109302C4552766
DiseaseSpontaneous abortion

LAMA4 COL4A6

5.50e-03109302C0000786

Protein segments in the cluster

PeptideGeneStartEntry
TGPEFNRVLFNFGGQ

FAM227B

376

Q96M60
GTLGFPGLNGFQGIE

COL4A6

321

Q14031
FAVGGQYVPGNGFSL

DNPEP

86

Q9ULA0
LPFQGIGTFGNQVGF

AKAP7

166

Q9P0M2
FQPTQTGFLQPGGAL

GPS2

236

Q13227
GLSEPQFVQFNGGFS

ADPRM

201

Q3LIE5
QGAQGNRYVGFGNTP

ARFGAP1

176

Q8N6T3
FIQELGFGVAPGFQT

ASIC2

256

Q16515
GFGVAPGFQTFVATQ

ASIC2

261

Q16515
FNFPGNFGGSNAFGP

RBM12

721

Q9NTZ6
GITFFPVQVNVGGQA

RBL2

756

Q08999
FSGQFVLGEPQGYGV

MORN1

86

Q5T089
QGNNSYVFPGVALGV

ME1

451

P48163
PFSGTIQGGLQDGFQ

LGALS9C

16

Q6DKI2
PFSGTIQGGLQDGFQ

LGALS9B

16

Q3B8N2
FIFGVTNFENQPGQG

DDIAS

126

Q8IXT1
GQGPQQVGAGQTFEY

LMAN2L

36

Q9H0V9
FGGETQQGVVFVFPG

ITGA5

416

P08648
AFSAQGLVPGGGVQF

C2CD3

1096

Q4AC94
GGIPFILTGEFFQQS

SLC2A9

431

Q9NRM0
FGPTGIGFGGLTQQV

CSRP3

176

P50461
LPVRGGNVGINSFGF

FASN

381

P49327
GFTVFAGVLNENGPG

HSD17B2

106

P37059
GQVGGQVGIFPSNYV

MAP3K11

86

Q16584
PLGIVQGFFAQNGVN

MCMBP

11

Q9BTE3
GPLAGDNFVRFVQGG

OSGIN1

446

Q9UJX0
GFEGGFNFRTLQPNG

LAMA4

1256

Q16363
SGFFFVAAGQQPGGS

SZT2

1776

Q5T011
LGFAPGLAGQQFFNG

TBX3

501

O15119
PVFLNGNSFIQGPSG

SIX4

361

Q9UIU6
EYGVQGLTGFQGFPG

COL24A1

1391

Q17RW2
QGSADGNGIQGFFYP

TMEM190

16

Q8WZ59
GQQFFGPLGAGQPLF

TBX2

476

Q13207
PGQGVQSQGKFSFGF

TNFRSF18

96

Q9Y5U5