Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Domain-

VPS11 RPAP3 INTS8 IFIT1 CRNKL1 IFIT1B CSTF3 ANAPC5 CRTAP LRP2BP

1.35e-05207162101.25.40.10
DomainTPR-like_helical_dom

VPS11 RPAP3 INTS8 IFIT1 CRNKL1 IFIT1B CSTF3 ANAPC5 CRTAP LRP2BP

3.72e-0523316210IPR011990
DomainARPC1

ARPC1A ARPC1B

7.48e-0521622IPR017383
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KRT72 SFPQ PDE6A ACTBL2 TM9SF3 GRIA4 KAT2A RNF17 NCAPH OGDH HNRNPD TASOR2 MDN1 SLC25A12 HOOK1 PCDHGA12 MLLT1 CDNF EIF3A TOP1MT RPL3 SYNCRIP MYBPC1 MYBPC2

7.34e-0814421632435575683
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SFPQ RPAP3 CAPN2 DLGAP5 LARS1 PPIL4 CHD7 NCAPH CREBBP ARPC1B HNRNPD FAM83H BLMH RLF CRNKL1 RAB3GAP1 MDN1 SLC25A12 TRIM32 EIF3A ANKRD52 RPL3 SYNCRIP

9.72e-0813531632329467282
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

INPPL1 ARPC1B HEATR6 EXOC6B ARHGAP29 CNDP2 AKAP11 DNMBP DOCK6

2.26e-07183163931932471
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

FRMPD2 TM9SF3 BTAF1 PFKFB3 NUDT13 IFIT1 PRPF18 SORCS1 BEND7 KCNMA1 EIF3A DNMBP

6.83e-074151631216385451
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NCAPD3 SFPQ INPP5D TM9SF3 LARS1 PTPN22 CHD7 SIN3A KAT2A CBFB CREBBP ARPC1B PRPF18 HNRNPD BLMH RLF GLO1 CSTF3 SYNCRIP

1.14e-0611031631934189442
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

NCAPD3 VRK2 CAPN2 TM9SF3 LARS1 SAMHD1 BTAF1 INTS8 CDKAL1 RAB3GAP1 SLC25A12 HOOK1 TRIM32 TBK1 CSTF3 TIMELESS ANAPC5

2.34e-069421631731073040
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

KRT72 CAPN2 TM9SF3 SAMHD1 NCAPH ARPC1B SORCS1 BLMH MDN1 SLC25A12 TRIM32 GLO1 EIF3A RPL3

2.46e-066471631426618866
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

NCAPD3 SFPQ ARPC1A TM9SF3 LARS1 PPIL4 SAMHD1 NCAPH OGDH HNRNPD BLMH CRNKL1 MDN1 GLO1 TBK1 CSTF3 EIF3A TDRD6 RPL3 SYNCRIP MYBPC1

3.56e-0614251632130948266
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

SFPQ ZC3HC1 CHD7 BTAF1 RNF17 NCAPH INTS8 HNRNPD EXOC5 MDN1 CSTF3 USP48 SYNCRIP

4.05e-065821631320467437
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FAM193B ZNF585A KALRN INPPL1 BTAF1 KAT2A FAM83H FAT1 MDN1 ZFP36L2 KCNH2 NADK MLLT1 DEPDC5 DENND5A DNMBP DOCK6 TEX19

4.83e-0611051631835748872
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

INPPL1 ACTBL2 CAPN2 ARPC1A LARS1 ZC3HC1 SAMHD1 NCAPH ARPC1B HNRNPD BLMH RAB3GAP1 SNX6 CNDP2 TIMELESS EIF3A DNMBP USP48 RPL3 CRTAP SYNCRIP

4.90e-0614551632122863883
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

SFPQ ACTBL2 ZC3HC1 SIN3A HNRNPD TASOR2 EIF3A RPL3 SYNCRIP

5.83e-06271163932433965
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

SFPQ ACTBL2 ARPC1A LARS1 BTAF1 HNRNPD FAM83H MYO5C BLMH CRNKL1 MDN1 GLO1 TBK1 CSTF3 EIF3A RPL3 SYNCRIP

7.04e-0610241631724711643
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

VRK2 SFPQ TUT4 RPAP3 ACTBL2 TM9SF3 OGDH IFIT1 HNRNPD CDKAL1 RAB3GAP1 VPS13D SPATS2L MDN1 SLC25A12 SNX6 GLO1 AKAP11 MIGA1 RPL3 SYNCRIP

7.49e-0614961632132877691
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

NCAPD3 SFPQ ACTBL2 TM9SF3 LARS1 SAMHD1 BTAF1 PFKFB3 FHIP2A NCAPH OGDH IFIT1 ARPC1B HNRNPD CDKAL1 EXOC5 RAB3GAP1 MDN1 EIF3A SYNCRIP

1.46e-0514401632030833792
Pubmed

Kalirin and CHD7: novel endothelial dysfunction indicators in circulating extracellular vesicles from hypertensive patients with albuminuria.

KALRN CHD7

2.18e-052163228152519
Pubmed

Fast and slow skeletal myosin binding protein-C and aging.

MYBPC1 MYBPC2

2.18e-052163236409445
Pubmed

Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2.

INPP5D INPPL1

2.18e-052163238309262
Pubmed

Overexpression of IFIT1 protects against LPS-induced acute lung injury via regulating CCL5-p65NF-κB signaling.

IFIT1 IFIT1B

2.18e-052163236446235
Pubmed

Autophagic degradation of KAT2A/GCN5 promotes directional migration of vascular smooth muscle cells by reducing TUBA/α-tubulin acetylation.

KAT2A DNMBP

2.18e-052163231878840
Pubmed

Ifit1 inhibits Japanese encephalitis virus replication through binding to 5' capped 2'-O unmethylated RNA.

IFIT1 IFIT1B

2.18e-052163223824812
Pubmed

Expression of CILP-2 and DDR2 and ultrastructural changes in the articular cartilage of patients with knee osteoarthritis undergoing total knee arthroplasty: a pilot morphological study.

DDR2 CILP2

2.18e-052163236370214
Pubmed

The association between expression of IFIT1 in podocytes of MRL/lpr mice and the renal pathological changes it causes: An animal study.

IFIT1 IFIT1B

2.18e-052163227823966
Pubmed

A viral RNA structural element alters host recognition of nonself RNA.

IFIT1 IFIT1B

2.18e-052163224482115
Pubmed

Sequestration by IFIT1 impairs translation of 2'O-unmethylated capped RNA.

IFIT1 IFIT1B

2.18e-052163224098121
Pubmed

Epistasis between serine protease inhibitor Kazal-type 5 (SPINK5) and thymic stromal lymphopoietin (TSLP) genes contributes to childhood asthma.

TSLP SPINK5

2.18e-052163224831437
Pubmed

IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I Interferon.

IFIT1 IFIT1B

2.18e-052163225927359
Pubmed

IFIT1 Exerts Opposing Regulatory Effects on the Inflammatory and Interferon Gene Programs in LPS-Activated Human Macrophages.

IFIT1 IFIT1B

2.18e-052163230282041
Pubmed

The SH2 domains of inositol polyphosphate 5-phosphatases SHIP1 and SHIP2 have similar ligand specificity but different binding kinetics.

INPP5D INPPL1

2.18e-052163219839650
Pubmed

Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families.

IFIT1 IFIT1B

2.18e-052163226157117
Pubmed

Ionotropic glutamate receptor GluA4 and T-type calcium channel Cav 3.1 subunits control key aspects of synaptic transmission at the mouse L5B-POm giant synapse.

GRIA4 CACNA1G

2.18e-052163226390982
Pubmed

HNRNP Q suppresses polyglutamine huntingtin aggregation by post-transcriptional regulation of vaccinia-related kinase 2.

VRK2 SYNCRIP

2.18e-052163230488434
Pubmed

Ifit1 Protects Against Lipopolysaccharide and D-galactosamine-Induced Fatal Hepatitis by Inhibiting Activation of the JNK Pathway.

IFIT1 IFIT1B

2.18e-052163226459629
Pubmed

SH2-containing inositol 5-phosphatases 1 and 2 in blood platelets: their interactions and roles in the control of phosphatidylinositol 3,4,5-trisphosphate levels.

INPP5D INPPL1

2.18e-052163212885297
Pubmed

2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo.

IFIT1 IFIT1B

2.18e-052163222589727
Pubmed

Mouse Ifit1b is a cap1-RNA-binding protein that inhibits mouse coronavirus translation and is regulated by complexing with Ifit1c.

IFIT1 IFIT1B

2.18e-052163233454014
Pubmed

Identification of a novel locus associated with skin colour in African-admixed populations.

PRPF18 BEND7

2.18e-052163228300201
Pubmed

Complete sequence of human fast-type and slow-type muscle myosin-binding-protein C (MyBP-C). Differential expression, conserved domain structure and chromosome assignment.

MYBPC1 MYBPC2

2.18e-05216328375400
Pubmed

Molecular cloning and expression analysis of the mouse Spot-2 gene in pituitary development.

LHX4 LHX3

2.18e-052163212684778
Pubmed

Isoform-specific interaction of the myosin-binding proteins (MyBPs) with skeletal and cardiac myosin is a property of the C-terminal immunoglobulin domain.

MYBPC1 MYBPC2

2.18e-05216329252413
Pubmed

Tyrosine-kinase-dependent recruitment of RGS12 to the N-type calcium channel.

CACNA1B RGS12

2.18e-052163211130074
Pubmed

Lhx4 surpasses its paralog Lhx3 in promoting the differentiation of spinal V2a interneurons.

LHX4 LHX3

2.18e-052163238970652
Pubmed

Identification and validation of Ifit1 as an important innate immune bottleneck.

IFIT1 IFIT1B

2.18e-052163222745654
Pubmed

Pathophysiology of syndromic combined pituitary hormone deficiency due to a LHX3 defect in light of LHX3 and LHX4 expression during early human development.

LHX4 LHX3

2.18e-052163215567726
Pubmed

Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals.

IFIT1 IFIT1B

2.18e-052163227240734
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

TUT4 KALRN ACTBL2 CAPN2 ARPC1A AOX1 BLMH RAB3GAP1 VPS13D FAT1 GLO1 BEND7 CNDP2 PLCD1 KNG1 MASP2

2.52e-0510161631619056867
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

RC3H2 VPS11 INPPL1 SNX6 TBK1 AKAP11 DNMBP KIF1C

2.61e-05251163829778605
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

KRT72 SFPQ RPAP3 ACTBL2 ARPC1A TM9SF3 LARS1 PPIL4 NCAPH ARPC1B HNRNPD FAM83H TASOR2 CRNKL1 SPATS2L EIF3A RPL3 SYNCRIP

2.72e-0512571631836526897
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

RC3H2 SFPQ TUT4 PPIL4 HNRNPD CRNKL1 HEATR6 SPATS2L PTCD2 CSTF3 EIF3A RPL3 SYNCRIP KIF1C

2.93e-058071631422681889
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

SFPQ ACTBL2 LARS1 MACROD1 OGDH HNRNPD MDN1 GLO1 CNDP2 CACNA1G EIF3A RPL3 MYO16 SYNCRIP

2.93e-058071631430575818
Pubmed

Postnatal gene expression in the normal mouse cornea by SAGE.

IFIT1 GRHL1 IFIT1B

3.54e-0514163314744882
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

SFPQ OGDH ARPC1B MDN1 UTP25 GLO1 CNDP2 NADK EIF3A

3.84e-05344163930333137
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

VRK2 SFPQ TM9SF3 LARS1 CHD7 NCAPH ARPC1B HNRNPD CDKAL1 FAM83H CRNKL1 MDN1 SLC25A12 CNDP2 EIF3A TOP1MT RPL3 SYNCRIP

5.01e-0513181631830463901
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

SFPQ LARS1 SAMHD1 SIN3A HNRNPD FAM83H CRNKL1 MDN1 CSTF3 EIF3A RPL3 SYNCRIP

5.15e-056381631233239621
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCAPD3 PDE6A TM9SF3 DLGAP5 PARD6G CHD7 IFIT1 ZNF251 CREBBP RAB3GAP1 MDN1 ANKRD52

5.15e-056381631231182584
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

NCAPD3 RC3H2 RPAP3 BTAF1 SIN3A FHIP2A TRIM32 TBK1 TIMELESS DENND5A ANAPC5 RPL3

6.15e-056501631238777146
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

FAM193B RC3H2 INPPL1 VPS13D ARHGAP29 AKAP11 EIF3A

6.17e-05209163736779422
Pubmed

Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11.

CHD7 CBFB

6.53e-053163229018080
Pubmed

SHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase.

INPP5D INPPL1

6.53e-053163215492005
Pubmed

Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2.

HIPK2 CREBBP

6.53e-053163211740489
Pubmed

Identification of a conserved protein that interacts with specific LIM homeodomain transcription factors.

LHX4 LHX3

6.53e-053163210788441
Pubmed

Novel characteristics of the function and induction of murine p56 family proteins.

IFIT1 IFIT1B

6.53e-053163218768971
Pubmed

Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) accelerates osteoclast formation by regulating signal transducer and activator of transcription 3 (STAT3) signalling.

IFIT1 IFIT1B

6.53e-053163235034537
Pubmed

The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1.

SIN3A CBFB

6.53e-053163214729951
Pubmed

Overexpression of SH2-Containing Inositol Phosphatase Contributes to Chronic Lymphocytic Leukemia Survival.

INPP5D INPPL1

6.53e-053163231836657
Pubmed

Further genetic evidence for three psoriasis-risk genes: ADAM33, CDKAL1, and PTPN22.

PTPN22 CDKAL1

6.53e-053163218923449
Pubmed

PEBP2-beta/CBF-beta-dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis.

HIPK2 CBFB

6.53e-053163218695000
Pubmed

Interaction of human calpains I and II with high molecular weight and low molecular weight kininogens and their heavy chain: mechanism of interaction and the role of divalent cations.

CAPN2 KNG1

6.53e-05316323038169
Pubmed

Structure, chromosome localization, and regulation of expression of the interferon-regulated mouse Ifi54/Ifi56 gene family.

IFIT1 IFIT1B

6.53e-05316327896268
Pubmed

γ-Aminobutyric acid type B (GABAB) receptor expression is needed for inhibition of N-type (Cav2.2) calcium channels by analgesic α-conotoxins.

CACNA1B GABBR1

6.53e-053163222613715
Pubmed

The Interferon-Induced Exonuclease ISG20 Exerts Antiviral Activity through Upregulation of Type I Interferon Response Proteins.

IFIT1 IFIT1B

6.53e-053163230232164
Pubmed

Mouse p56 blocks a distinct function of eukaryotic initiation factor 3 in translation initiation.

IFIT1 IFIT1B

6.53e-053163215561726
Pubmed

Expression and function of the LIM homeobox containing genes Lhx3 and Lhx4 in the mouse placenta.

LHX4 LHX3

6.53e-053163218425848
Pubmed

The interaction between interferon-induced protein with tetratricopeptide repeats-1 and eukaryotic elongation factor-1A.

IFIT1 IFIT1B

6.53e-053163219856081
Pubmed

A PP6-ASK3 Module Coordinates the Bidirectional Cell Volume Regulation under Osmotic Stress.

MAP3K15 ANKRD52

6.53e-053163229539411
Pubmed

The C-terminal IgI domains of myosin-binding proteins C and H (MyBP-C and MyBP-H) are both necessary and sufficient for the intracellular crosslinking of sarcomeric myosin in transfected non-muscle cells.

MYBPC1 MYBPC2

6.53e-053163212154082
Pubmed

Common variants on 2p16.1, 6p22.1 and 10q24.32 are associated with schizophrenia in Han Chinese population.

VRK2 GABBR1

6.53e-053163227922604
Pubmed

In-vitro acetylation of SARS-CoV and SARS-CoV-2 nucleocapsid proteins by human PCAF and GCN5.

KAT2A CREBBP

6.53e-053163233894414
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TUT4 HTATIP2 AOX1 SIN3A KAT2A TUBGCP5 CREBBP CDKAL1 FAM83H FAT1 SLC25A12 UTP25 TBK1 MLLT1 ANAPC5 ANKRD52

7.66e-0511161631631753913
Pubmed

Proteomics analysis of the estrogen receptor alpha receptosome.

SFPQ LARS1 HNRNPD SNX6 SYNCRIP

7.92e-0593163520348541
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

NCAPD3 VRK2 ACTBL2 TM9SF3 CHD7 KAT2A INTS8 GREB1L CRNKL1 SPATS2L MDN1 UTP25 ZFP36L2 TRIM32 CSTF3 MLLT1 EIF3A DNMBP ANAPC5

8.12e-0514971631931527615
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

SFPQ ACTBL2 NCAPH OGDH HNRNPD MDN1 SYNCRIP

8.27e-05219163731353912
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

SFPQ HIPK2 SIN3A HNRNPD CRNKL1 CSTF3 USP48

8.51e-05220163735785414
Pubmed

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.

SFPQ ACTBL2 KAT2A OGDH ARPC1B HNRNPD EIF3A TDRD6 RPL3 SYNCRIP MYBPC2

9.88e-055801631135676659
Pubmed

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.

SFPQ INPPL1 TM9SF3 MACROD1 HIPK2 PFKFB3 PLEKHA6 ARPC1B HNRNPD RAB3GAP1 DNAH17 GABBR1 CRTAP SYNCRIP KIF1C

9.89e-0510211631526760575
Pubmed

TRIM37 Mediates Chemoresistance and Maintenance of Stemness in Pancreatic Cancer Cells via Ubiquitination of PTEN and Activation of the AKT-GSK-3β-β-Catenin Signaling Pathway.

SFPQ ACTBL2 ARPC1B HNRNPD FAM83H MYO5C RPL3 SYNCRIP

1.02e-04305163833194618
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

LARS1 CHD7 SIN3A NCAPH HNRNPD MDN1 USP48 ANAPC5 SYNCRIP

1.08e-04394163927248496
Pubmed

Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics.

CEP85L INPP5D PTPN22

1.09e-0420163331591574
Pubmed

The nuclear transcription factor RARalpha associates with neuronal RNA granules and suppresses translation.

SFPQ HNRNPD EIF3A SYNCRIP

1.23e-0454163418495661
Pubmed

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.

IFIT1 TBK1 IFIT1B

1.26e-0421163319158679
Pubmed

Metabolic regulation of homologous recombination repair by MRE11 lactylation.

KAT2A CREBBP

1.30e-044163238128537
Pubmed

Interferon-induced protein Ifit2 protects mice from infection of the peripheral nervous system by vesicular stomatitis virus.

IFIT1 IFIT1B

1.30e-044163224991014
Pubmed

Coordinated regulation and widespread cellular expression of interferon-stimulated genes (ISG) ISG-49, ISG-54, and ISG-56 in the central nervous system after infection with distinct viruses.

IFIT1 IFIT1B

1.30e-044163217079283
Pubmed

KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase.

KAT2A OGDH

1.30e-044163229211711
Pubmed

The glucocorticoid attenuated response genes GARG-16, GARG-39, and GARG-49/IRG2 encode inducible proteins containing multiple tetratricopeptide repeat domains.

IFIT1 IFIT1B

1.30e-04416328660659
Pubmed

Tissue-specific and inducer-specific differential induction of ISG56 and ISG54 in mice.

IFIT1 IFIT1B

1.30e-044163217553874
Pubmed

Sendai virus pathogenesis in mice is prevented by Ifit2 and exacerbated by interferon.

IFIT1 IFIT1B

1.30e-044163225231314
Pubmed

Structural basis for partial redundancy in a class of transcription factors, the LIM homeodomain proteins, in neural cell type specification.

LHX4 LHX3

1.30e-044163222025611
Pubmed

Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis.

NCAPD3 NCAPH

1.30e-044163227737959
Pubmed

Absence of SHIP-1 results in constitutive phosphorylation of tank-binding kinase 1 and enhanced TLR3-dependent IFN-beta production.

INPP5D TBK1

1.30e-044163220100929
InteractionDUSP16 interactions

TUT4 NCAPH TUBGCP5 FAM83H TASOR2 RAB3GAP1 HOOK1 TRIM32 AKAP11 EIF3A ANAPC5

3.34e-0623716111int:DUSP16
GeneFamilyFibronectin type III domain containing|I-set domain containing|Myosin binding proteins

MYBPC1 MYBPC2

9.14e-0481052658
GeneFamilyActin related protein 2/3 complex

ARPC1A ARPC1B

1.17e-039105239
GeneFamilyExocyst complex

EXOC5 EXOC6B

1.17e-03910521055
CoexpressionGSE14000_TRANSLATED_RNA_VS_MRNA_4H_LPS_DC_UP

TUT4 RPAP3 SCYL3 ZC3HC1 KAT2A INTS8 HNRNPD TASOR2 CNDP2 USP48

5.11e-0719916310M3328
CoexpressionONKEN_UVEAL_MELANOMA_UP

SFPQ ADAM23 CAPN2 HTATIP2 DLGAP5 MACROD1 CHD7 BTAF1 PFKFB3 CBFB INTS8 HNRNPD ZFP36L2 TBK1 PGAP1 DENND5A USP48 SYNCRIP

2.27e-0679016318M12490
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

TUT4 DDR2 DLGAP5 BTAF1 CBFB CREBBP RLF RAB3GAP1 FAT1 MDN1 SLC25A12 ZFP36L2 ARHGAP29 AKAP11 EIF3A DENND5A DNMBP

2.60e-0585616317M4500
CoexpressionGSE41867_NAIVE_VS_EFFECTOR_CD8_TCELL_UP

HTATIP2 DLGAP5 ZC3HC1 SAMHD1 IFIT1 GLO1 ANAPC5 SPINK5

3.78e-052001638M9474
CoexpressionGSE33424_CD161_INT_VS_NEG_CD8_TCELL_UP

SAMHD1 CHD7 PFKFB3 IFIT1 SAMD9L MDN1 SLC25A12 IFIT1B

3.78e-052001638M8554
CoexpressionGSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_UP

LARS1 SAMHD1 PFKFB3 IFIT1 SAMD9L SLC25A12 IFIT1B DNMT3L

3.78e-052001638M8564
CoexpressionGSE3039_NKT_CELL_VS_ALPHABETA_CD8_TCELL_DN

TUT4 ADAM23 CAPN2 SAMHD1 BTAF1 RGS12 EIF3A CRTAP

3.78e-052001638M6430
CoexpressionNAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_UP

VRK2 HTATIP2 LARS1 HIPK2 SAMHD1 ARPC1B RAB3GAP1 SAMD9L SNX6 CNDP2 NADK CRTAP SYNCRIP

5.31e-0556216313M41008
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN GRIA4 INTS8 KCNMA1 ACCS PLCD1 CDH6

3.28e-061711637b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN GRIA4 INTS8 KCNMA1 ACCS PLCD1 CDH6

3.28e-0617116379d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCellTuft-tuft-4|World / Class top

KALRN INPP5D PFKFB3 SAMD9L MDN1 SLC25A12 COA5

3.68e-061741637d6f306ebf66061bf9e9742000bfedce12d277452
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR2 NXPH1 MACROD1 RGS12 GREB1L CILP2 MYO16

5.90e-061871637d2ffb2f34f07b0dd5d3cb3ee0275f46ebecf4146
ToppCellSevere-Treg|Severe / Disease group and Cell class

HTATIP2 SAMHD1 IFIT1 MYO5C SPATS2L EXOC6B CRTAP

7.51e-0619416377d232d87262ec5f505901345da5113cabf821321
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

RC3H2 INPP5D SAMHD1 EFHC2 SPATS2L CNDP2 AKAP11

8.03e-06196163709d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM23 FHOD3 GREB1L RHBDL2 KCNMA1 MASP2

2.57e-051581636f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM23 FHOD3 GREB1L RHBDL2 KCNMA1 MASP2

2.57e-0515816368c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellNS-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SORCS1 FAT1 KCNH2 TOP1MT DOCK6 MYO16

2.76e-0516016368a4746463ca1976f7d6de803496c851249ced797
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DDR2 PARD6G GRIA4 COLEC12 CDH6 GABBR1

3.87e-0517016365570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN22 SAMHD1 ARPC1B GRHL1 CILP2 ZFP36L2

4.13e-051721636adf016e5856bc85e7bed58aee09ade483b9dcb00
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN22 SAMHD1 NCAPH ZFP36L2 PGAP1 PDE5A

4.27e-051731636de124fb7ded04664d4184bf12f1f201c0784f07c
ToppCellTCGA-Colorectal-Recurrent_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

UGT3A1 AKR1D1 SLCO1B1 ITIH1 KNG1 MASP2

4.55e-0517516367f74961436f88c0e380819095e6104489914d765
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1B NXPH1 FAM83H SORCS1 KCNV1 MAP3K15

4.55e-0517516368362a46f5804333baa84cd56d450bc147f372a7e
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1B NXPH1 FAM83H SORCS1 KCNV1 MAP3K15

4.55e-0517516368b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCellTCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

UGT3A1 AKR1D1 SLCO1B1 ITIH1 KNG1 MASP2

4.55e-051751636bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIPK2 PFKFB3 RGS12 CDKAL1 FAT1 DNAH17

4.70e-051761636327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCelldroplet-Tongue-nan-24m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFIT1 GRHL1 SAMD9L EIF3A KIF1C SPINK5

4.70e-0517616369739b0653c511ab017507a0c7ee4f6d7082e87db
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP85L PFKFB3 IFIT1 SAMD9L ARHGAP29 TIMELESS

4.85e-051771636ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP85L PFKFB3 IFIT1 SAMD9L ARHGAP29 TIMELESS

4.85e-051771636f471f7747d6e8db7546899019af9508f48a14f89
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP85L PFKFB3 IFIT1 SAMD9L ARHGAP29 TIMELESS

4.85e-051771636cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

MIOX UGT3A1 AOX1 SORCS1 ALDOB CDH6

5.00e-05178163623a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

AOX1 FHOD3 PLEKHA6 FAT1 ALDOB CDH6

5.33e-051801636358923e4228035a3e90e2957392089219e90dcd7
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

UGT3A1 AOX1 FHOD3 PLEKHA6 FAT1 CDH6

5.33e-051801636864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR2 NXPH1 RGS12 CILP2 MYO16 TEX19

5.66e-05182163686a2330ada7637144a67afbf9f3a902901ab1130
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5|TCGA-Liver / Sample_Type by Project: Shred V9

SFPQ RPAP3 DLGAP5 NCAPH INTS8 USP48

5.84e-051831636f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIPK2 PFKFB3 RGS12 FAT1 DNAH17 ARHGAP29

5.84e-05183163692fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

CACNA1B ADAM23 UGT1A7 PARD6G BLMH PGAP1

6.02e-051841636ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR2 NXPH1 RGS12 GREB1L CILP2 MYO16

6.20e-05185163679cff4f3c6ae8e5ea60e8eae082b9275f2679ee9
ToppCellControl-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

HTATIP2 SAMHD1 CDKAL1 SPATS2L PGAP1 USP48

6.20e-051851636e481cacda0b6b25f5f0062b962df9a442053ac30
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR2 NXPH1 RGS12 GREB1L FAT1 MYO16

6.39e-051861636310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MIOX AOX1 FHOD3 PLEKHA6 SORCS1 ALDOB

6.39e-0518616365784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MIOX AOX1 PLEKHA6 SORCS1 ALDOB CDH6

6.58e-051871636dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MIOX AOX1 PLEKHA6 SORCS1 ALDOB CDH6

6.58e-051871636f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR2 NXPH1 RGS12 GREB1L FAT1 MYO16

6.77e-0518816360501a8aa850bd2e347020abd1cac4d8075738189
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR2 NXPH1 RGS12 GREB1L FAT1 MYO16

6.77e-051881636433a25fe52914e07e7ba695881f9bcca2d9467ff
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR2 NXPH1 MACROD1 RGS12 GREB1L MYO16

6.77e-051881636ee572246e0c2f41bdbc29a03edc67b831af95c09
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ZNF251 RGS12 VPS13D SPATS2L PGAP1 AKAP11

6.77e-0518816362c4e791df69a9df29922f9117e5cac7787c129ce
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZNF251 RGS12 VPS13D SPATS2L PGAP1 AKAP11

6.77e-051881636b1ec7c45aedcc3d22cac898c6a3679e7f8b44c77
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR2 NXPH1 RGS12 GREB1L FAT1 MYO16

6.98e-051891636f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCellGlobus_pallidus-Endothelial|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

DDR2 SAMD9L ARHGAP29 PDE5A DOCK6 CRTAP

6.98e-051891636ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DDR2 FHOD3 COLEC12 KCNMA1 CDH6 MYO16

7.39e-05191163614057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

SFPQ TUT4 PPIL4 RLF PGAP1 DNMBP

7.39e-0519116361ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR2 NXPH1 RGS12 GREB1L FAT1 MYO16

7.39e-0519116367b386512284dfaa0e95358b28ee82632ee965e64
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR2 NXPH1 RGS12 GREB1L FAT1 MYO16

7.39e-051911636fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCellCF-Lymphoid|CF / Disease state, Lineage and Cell class

INPP5D PTPN22 TASOR2 MDN1 AKAP11 USP48

7.83e-05193163611de07d13a7da223990b56fa89ba7fc1c3dd0122
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

SFPQ TUT4 IFIT1 SAMD9L SPATS2L ZFP36L2

7.83e-0519316367256a5a491536c525b31ae96d47ab5c6303cb73a
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DDR2 FHOD3 SORCS1 KCNMA1 PDE5A CACNA1G

8.29e-051951636c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DDR2 FHOD3 SORCS1 KCNMA1 PDE5A CACNA1G

8.29e-051951636ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCell(01)_IL1RL1+-(1)_GFP|(01)_IL1RL1+ / shred by cell type by condition

FAM193B CAPN2 ARPC1A ARPC1B RPL3 SPINK5

8.52e-051961636b598b1112242534e139318012b257ed3cb09da83
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

DDR2 PARD6G FHOD3 FAT1 RHBDL2 KCNMA1

9.01e-0519816361f956e369e00d37835095a001db4b62a79014532
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

DDR2 PARD6G FHOD3 FAT1 RHBDL2 KCNMA1

9.01e-051981636dc6fbad0ecdd057189f71afcdb6aca25207314a3
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-CD8+_Tcm|Bac-SEP / Disease, condition lineage and cell class

MACROD1 EFHC2 RHBDL2 MDN1 PGAP1 RPL3

9.01e-05198163684a07dea22b7771b34118729607b48c2d75df870
ToppCellParenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RAB3GAP1 HEATR6 KCNH2 KCNMA1 CDH6 KIF1C

9.01e-051981636cc2b5b632e73e44bb60050f0db10d8f0dbb859fa
ToppCellVE-CD4-antiviral_CD4|VE / Condition, Cell_class and T cell subcluster

SAMHD1 IFIT1 SAMD9L SPATS2L SNX6 PGAP1

9.26e-051991636056a0538ca5e825ae6195b4c76c208708a014533
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NCAPD3 SFPQ DLGAP5 AKR1D1 NCAPH ALDOB

9.52e-0520016364cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

FHOD3 FAT1 KCNH2 KCNMA1 PDE5A CDH6

9.52e-052001636c5e051f1aac8dda376c342a9932785a23450e073
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-CDH12|Neuronal / cells hierarchy compared to all cells using T-Statistic

DDR2 NXPH1 MACROD1 RGS12 GREB1L MYO16

9.52e-052001636c74bc12e13d002dedaaf75a2244ec111e47524e1
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-CDH12-L1-2|Neuronal / cells hierarchy compared to all cells using T-Statistic

DDR2 NXPH1 MACROD1 RGS12 GREB1L MYO16

9.52e-052001636ead9eb579bb25fde05fc15602e3d05ab6617f7ac
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

CEP85L SAMHD1 IFIT1 RHBDL2 SAMD9L ARHGAP29

9.52e-052001636edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR|Neuronal / cells hierarchy compared to all cells using T-Statistic

DDR2 NXPH1 RGS12 GREB1L FAT1 MYO16

9.52e-052001636862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SFPQ SAMHD1 BTAF1 IFIT1 SAMD9L EIF3A

9.52e-05200163612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DDR2 SORCS1 FAT1 SPATS2L KCNH2 PDE5A

9.52e-05200163609537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellVE|World / Condition, Cell_class and T cell subcluster

SAMHD1 IFIT1 HNRNPD SAMD9L SNX6 ZFP36L2

9.52e-0520016368ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1|Neuronal / cells hierarchy compared to all cells using T-Statistic

DDR2 NXPH1 RGS12 GREB1L FAT1 MYO16

9.52e-052001636a91345f268f13170c27309333603eb82400c9947
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FAT1 SPATS2L KCNH2 KCNMA1 PDE5A CDH6

9.52e-05200163608bf8c00eee6468215edb3611296bfc8784c4d56
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FAT1 SPATS2L KCNH2 KCNMA1 PDE5A CDH6

9.52e-052001636dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-|Neuronal / cells hierarchy compared to all cells using T-Statistic

DDR2 NXPH1 RGS12 GREB1L FAT1 MYO16

9.52e-052001636d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-stromal_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PFKFB3 COLEC12 SPATS2L SNX6 KCNMA1 CNDP2

9.52e-052001636af743dfef7e7cfaef1c494999757123f93a213e3
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP5 PP2D1 IFIT1 RHBDL2 LRP2BP

1.21e-041311635419a0a83b38eaea890d065c3f252ef83c2d37b5b
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AOX1 PLEKHA6 GREB1L KCNMA1 AKAP11

1.25e-0413216354152529611eeacf0c547e2a134d5b98c45426b13
ToppCell356C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FAM193B PDE6A INPPL1 MACROD1 PARD6G

1.44e-041361635edfd453c9a650d69d05a5a3ab15f7df56349fa86
ToppCell356C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FAM193B PDE6A INPPL1 MACROD1 PARD6G

1.44e-04136163503e4e2353c23ceffde35b2d0aadd15299e3db09f
Diseaseallopregnanolone sulfate measurement, pregnanolone sulfate measurement

UGT3A1 SLCO1B1

2.85e-0521582EFO_0800375, EFO_0801074
DiseaseN-acetyl-isoputreanine measurement

SPATS2L KCNH2 KIF1C

4.14e-05131583EFO_0800107
Diseasedisintegrin and metalloproteinase domain-containing protein 23 measurement

ADAM23 SLCO1B1

8.52e-0531582EFO_0801530
Diseasecalpain-2 catalytic subunit measurement

CAPN2 ITIH1

1.70e-0441582EFO_0801445
Diseasemetabolite measurement

UGT1A7 DDR2 UGT3A1 AKR1D1 SLCO1B1 ZNF251 CDKAL1 SORCS1 KCNH2 DNMBP KNG1

2.28e-0456015811EFO_0004725
DiseaseCombined pituitary hormone deficiencies, genetic form

LHX4 LHX3

2.82e-0451582cv:C4273747
Diseasepregnenolone sulfate measurement

UGT3A1 SLCO1B1

2.82e-0451582EFO_0800303
DiseaseX-11445--5-alpha-pregnan-3beta,20alpha-disulfate measurement

UGT3A1 SLCO1B1

4.21e-0461582EFO_0021238
DiseaseGlcNAc sulfate conjugate of C21H34O2 steroid measurement

UGT3A1 SLCO1B1

4.21e-0461582EFO_0800663
DiseaseX-21471 measurement

SLCO1B1 DNMBP

4.21e-0461582EFO_0800818
Diseaseglycocholenate sulfate measurement

SLCO1B1 DNMBP

4.21e-0461582EFO_0800276
Disease5alpha-pregnan-diol disulfate measurement

UGT3A1 SLCO1B1

4.21e-0461582EFO_0800286
Diseaseresponse to ranibizumab

EXOC5 KCNMA1

4.21e-0461582EFO_0008348
Diseaselung disease severity measurement

VRK2 NXPH1 KCNMA1 PDE5A MYO16

4.44e-041181585EFO_0007744
Diseasereticulocyte measurement

INPP5D MACROD1 SLCO1B1 ARPC1B CDKAL1 FAT1 HOOK1 ZFP36L2 TBK1 DNAH17 NADK PDE5A DEPDC5 USP48 MYBPC1

5.58e-04105315815EFO_0010700
Diseaseserum alanine aminotransferase measurement, response to combination chemotherapy

DDR2 CDKAL1 BEND7 DEPDC5

5.82e-04711584EFO_0004735, EFO_0007965
Diseaseacisoga measurement

KCNH2 KIF1C

5.88e-0471582EFO_0800068
Diseasepanhypopituitarism (is_implicated_in)

LHX4 LHX3

5.88e-0471582DOID:9410 (is_implicated_in)
DiseaseX-21339 measurement

UGT1A7 SLCO1B1

5.88e-0471582EFO_0800808
Diseasepregnanediol-3-glucuronide measurement

UGT3A1 SLCO1B1

7.81e-0481582EFO_0800341
DiseaseX-11880 measurement

UGT1A7 SLCO1B1

1.00e-0391582EFO_0800698
DiseaseX-21467 measurement

SLCO1B1 DNMBP

1.00e-0391582EFO_0020007
Diseasethyroxine measurement

UGT1A7 LHX3 SLCO1B1 BEND7

1.05e-03831584EFO_0005130
Diseaseautosomal dominant nonsyndromic deafness (is_implicated_in)

GREB1L USP48

1.52e-03111582DOID:0050564 (is_implicated_in)
DiseaseX-21796 measurement

UGT1A7 SLCO1B1

1.52e-03111582EFO_0800825
Diseasepregnenediol disulfate (C21H34O8S2) measurement

UGT3A1 SLCO1B1

1.52e-03111582EFO_0800279
Diseasereticulocyte count

INPP5D MACROD1 SLCO1B1 ARPC1B GREB1L FAT1 HOOK1 ZFP36L2 TBK1 DNAH17 NADK DEPDC5 USP48 KIF1C

1.53e-03104515814EFO_0007986
DiseaseQRS complex, QRS duration

CEP85L DDR2 FHOD3

1.81e-03451583EFO_0005054, EFO_0005055
Diseaseeye disease

FRMPD2 KCNMA1 PTCD2

1.81e-03451583EFO_0003966
Diseasebiliverdin measurement

UGT1A7 SLCO1B1

1.82e-03121582EFO_0021033
Diseaseaspartate aminotransferase to alanine aminotransferase ratio

PTPN22 ZNF251 RGS12 CILP2 ARHGAP29 DNMBP

1.87e-032391586EFO_0010934
Diseaseepilepsy (implicated_via_orthology)

CACNA1B KALRN KCNH2 KCNMA1 DEPDC5

1.89e-031631585DOID:1826 (implicated_via_orthology)
Diseaseglycochenodeoxycholate glucuronide (1) measurement

SLCO1B1 CACNA1G

2.14e-03131582EFO_0800474
Disease5alpha-pregnan-3beta,20beta-diol monosulfate (1) measurement

UGT3A1 SLCO1B1

2.14e-03131582EFO_0800284
DiseaseAgents acting on the renin-angiotensin system use measurement

ARPC1A MACROD1 HIPK2 ZC3HC1 ARPC1B RGS12 ANAPC5

2.26e-033351587EFO_0009931
Diseaseelectrocardiography

CEP85L DDR2 FHOD3 PLEKHA6 SPATS2L KCNH2 GALNT8 NADK CACNA1G

2.30e-035301589EFO_0004327
DiseaseX-21470 measurement

SLCO1B1 DNMBP

2.49e-03141582EFO_0800817
Diseasemyelodysplastic syndrome (implicated_via_orthology)

CREBBP SAMD9L

2.86e-03151582DOID:0050908 (implicated_via_orthology)
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

NCAPD3 NCAPH

3.25e-03161582DOID:0070296 (is_implicated_in)
DiseaseDrug habituation

GRIA4 FHOD3 MYO5C COLEC12

3.45e-031151584C0013170
DiseaseDrug abuse

GRIA4 FHOD3 MYO5C COLEC12

3.45e-031151584C0013146
DiseasePrescription Drug Abuse

GRIA4 FHOD3 MYO5C COLEC12

3.45e-031151584C4316881
DiseaseSubstance-Related Disorders

GRIA4 FHOD3 MYO5C COLEC12

3.45e-031151584C0236969
DiseaseDrug Use Disorders

GRIA4 FHOD3 MYO5C COLEC12

3.45e-031151584C0013222
DiseaseDrug Dependence

GRIA4 FHOD3 MYO5C COLEC12

3.45e-031151584C1510472
DiseaseSubstance Dependence

GRIA4 FHOD3 MYO5C COLEC12

3.45e-031151584C0038580
DiseaseSubstance Use Disorders

GRIA4 FHOD3 MYO5C COLEC12

3.45e-031151584C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

GRIA4 FHOD3 MYO5C COLEC12

3.45e-031151584C0029231
DiseaseSubstance abuse problem

GRIA4 FHOD3 MYO5C COLEC12

3.56e-031161584C0740858
DiseaseX-21441 measurement

UGT1A7 DNMBP

3.68e-03171582EFO_0800814
Diseasefree androgen index

UGT1A7 AKR1D1 CHD7 SIN3A SLCO1B1 DNMBP USP48

4.14e-033741587EFO_0007005
Diseasemetabolonic lactone sulfate measurement

ARPC1A SLCO1B1

4.59e-03191582EFO_0800659
Diseasemonocyte count

KALRN INPP5D DDR2 MACROD1 PTPN22 PLEKHA6 NCAPH OGDH SLCO1B1 CDKAL1 CILP2 MLLT1 PDE5A MYO16 MYBPC1

4.97e-03132015815EFO_0005091

Protein segments in the cluster

PeptideGeneStartEntry
KKRSCYVSLDFEGDL

ACTL10

81

Q5JWF8
KFSKCSILEYRDFLQ

ADAM23

471

O75077
DCEVCKEFLNRFYKS

CDNF

36

Q49AH0
CKDKFLDALFLYDDD

DNMT3L

76

Q9UJW3
LREEVAKFLSFYCKS

ACCS

141

Q96QU6
RDVKEKLCYVALDFE

ACTBL2

211

Q562R1
KIAEGKVRREDIFYC

AKR1D1

71

P51857
LSERCAQYKKDGVDF

ALDOB

131

P05062
SCDFKCRIFSAYIKE

ARPC1B

161

O15143
TSRVYKFCSKLAEVF

CREBBP

1171

Q92793
CGSFDFEDKVVKLYA

AKAP11

676

Q9UKA4
VQKRFDKLLDFYNCT

DNMBP

1121

Q6XZF7
AVRDFAREYVCLAFK

AMIGO3

241

Q86WK7
LKESRRKEAFFCLEF

ANKRD52

521

Q8NB46
GKFFYCTDESKELER

CACNA1B

1306

Q00975
KSDESLEKYFSCFVA

CHD7

2006

Q9P2D1
SCDFKCRVFSAYIKE

ARPC1A

161

Q92747
FTEAEKFLATDKVFC

AOX1

656

Q06278
LYRASCFKVTKRDED

RC3H2

246

Q9HBD1
DFVTEFFKICRRKES

RAB3GAP1

326

Q15042
CQFLREIDYKTAFKS

INTS8

901

Q75QN2
RCASALEKFFYFKLK

KAT2A

816

Q92830
FSVSCEAEKRKSDYI

PTPN22

156

Q9Y2R2
FRYVDDKAAQVFKLD

PCDHGA12

281

O60330
KTGESLCYAFIEFEK

PPIL4

276

Q8WUA2
FAKVDCKERIRDVVY

ANAPC5

701

Q9UJX4
EKFADRLLKDFTDFC

DEPDC5

1566

O75140
KFEKDVYRAEISEFA

FAT1

366

Q14517
YCKAEFAKLVEEFRS

MDN1

2191

Q9NU22
KSKEARKYIFNCLDD

HIPK2

461

Q9H2X6
EAKVEELKFDRYSVF

HTATIP2

151

Q9BUP3
DAKEVKRAFFYCKAC

KCNMA1

666

Q12791
FKVTYDVSRDKICDL

ITIH1

256

P19827
SCFIKYFELQFCERK

MYO16

551

Q9Y6X6
VKIFKEVQCYFRSEA

DDR2

296

Q16832
ASFEELCSEYRKSRK

SPINK5

431

Q9NQ38
ARKVFCEVYKERLFG

GABBR1

371

Q9UBS5
ERKVEIAFYRKDGSC

KCNH2

91

Q12809
DKKKNRGFCFLEYED

SYNCRIP

281

O60506
FSACYFTLKLKEAAV

KCNV1

431

Q6PIU1
KIYDCDAFTRNFLRK

EFHC2

166

Q5JST6
VALIEFCYKSRAEAK

GRIA4

831

P48058
AVKKKFCTFREDYDD

NADK

156

O95544
YSACKRFEELGVKFV

GLO1

136

Q04760
TEKDEKDFAAYLAFC

PDE5A

296

O76074
HFCDFVDILTEYKTK

PDE6A

161

P16499
KFENEEFFRKLSREC

CBFB

11

Q13951
EFFRKLSRECEIKYT

CBFB

16

Q13951
FSVEKEIFEDAKLFC

COLEC12

621

Q5KU26
YCSKDKSVAFKIFEL

CSTF3

421

Q12996
AKENDFKAFFIESVC

PFKFB3

141

Q16875
VDKNIFRDCNKIAFY

GANC

16

Q8TET4
KDFLRYSEKAGLECS

KALRN

2071

O60229
QKSEDTIDFLEFKYC

HEATR6

1051

Q6AI08
AVKEICYEVALADFR

KIF1C

751

O43896
SRGESVYCKDDFFKR

LHX3

71

Q9UBR4
RAGSVYCKEDFFKRF

LHX4

71

Q969G2
KCVAFSKRIADYDEV

LRP2BP

261

Q9P2M1
YFISFKEELAEIEKC

TUBGCP5

371

Q96RT8
KQKCFSEREASDILY

RPS6KA6

511

Q9UK32
IKEFIYACLKFSEDL

EXOC6B

501

Q9Y2D4
LYLCDSFVGADLKKF

GREB1L

1851

Q9C091
KTRYLFELKEDDDAC

NUDT13

26

Q86X67
LRFYDCSAVEVKSKF

PARD6G

11

Q9BYG4
FCDVLRAIRDYAFKA

PLCD1

366

P51178
EKTEFFKFLLDRVSC

SCYL3

266

Q8IZE3
KYDKICEEAFARSKD

OGDH

561

Q02218
YLKEAIFSDCFKEVI

ARHGAP29

61

Q52LW3
AICDVAEYRKCAKDF

EXOC5

631

O00471
EFDRCRKLYEKFLEF

CRNKL1

621

Q9BZJ0
AKQRCIDIADYKESF

GRHL1

331

Q9NZI5
CLAAFEYKGKKAFER

DOCK6

1291

Q96HP0
LYEDFAKSRAKCDVD

BTAF1

1531

O14981
LICDTFRKIVDSKYF

CACNA1G

731

O43497
YDEVFELVKVFADCK

DNAH17

461

Q9UFH2
AFKFCLQYTRKAEFR

EIF3A

181

Q14152
VEYFKRFCLDSAKQT

FAM193B

866

Q96PV7
EYCVADFKRVVDFLK

CDKAL1

336

Q5VV42
ACEGSREIKDFKDFY

CRTAP

246

O75718
KEFFFLDSETRLCKI

FRMPD2

391

Q68DX3
VFDNIRFDTFKLDKY

GALNT8

306

Q9NY28
KFCRIISEFALEYRT

FHOD3

1241

Q2V2M9
NYERAKTCFEKALEG

IFIT1B

156

Q5T764
RFKQFEGLVDDCEYK

DLGAP5

481

Q15398
LDCKYKFESCSKEDF

CEP85L

226

Q5SZL2
KRYAFLRCDDEKEQF

DENND5A

916

Q6IQ26
DKVERCYFFLSAFVD

BLMH

106

Q13867
SDKQREEHYFCKDFV

MACROD1

106

Q9BQ69
AKYILKDSFSIFCET

MASP2

316

O00187
NYERAKACFEKVLEV

IFIT1

156

P09914
KYFIDFVARETTCSK

KNG1

316

P01042
LFRKLVCAFFDDKTL

BEND7

311

Q8N7W2
FYETFVCEKAKADQL

CDH6

491

P55285
EILESECKVAKFRDY

HOOK1

646

Q9UJC3
NKEEPRKVCFTYDLF

MLLT1

91

Q03111
EFCKELAAIAFVKYH

FHIP2A

746

Q5W0V3
RVYSRFEVFCKKEEA

FAM83H

1131

Q6ZRV2
DFCIRVFSEKKADYQ

CAPN2

496

P17655
VKFTKDTYVLAFAIC

PTCD2

196

Q8WV60
VREFNKFDLYTKCPD

MIOX

246

Q9UGB7
RIYKDIFLDSDCKDD

MAP3K15

366

Q6ZN16
FLKDIFDFEKVRYSS

MIGA1

566

Q8NAN2
YFSKFGEVVDCTLKL

HNRNPD

116

Q14103
SRATAQKDEKCYEVF

PLAC1

136

Q9HBJ0
FKKEELNFTHICEYT

UTP25

631

Q68CQ4
VSRCDYFLAKIKQAD

TRIM32

236

Q13049
EFLKVKAQAFRCSLY

TDRD6

871

O60522
GYTVFSCFDKALLKD

RHBDL2

261

Q9NX52
KYDEELGKAARFSCD

SPATS2L

326

Q9NUQ6
YKRFIKFARVCEVDN

SAMHD1

331

Q9Y3Z3
SFNCRIEYEKVDKAT

NXPH1

191

P58417
FAEHISDECKRRFYK

RPL3

106

P39023
FEFQAAKDKYRELAV

LARS1

826

Q9P2J5
YFEESEINEAKKCIR

SAMD9L

271

Q8IVG5
KEYVFADSKKREGFC

INPP5D

371

Q92835
KDFIFVSARKREAFC

INPPL1

391

O15357
FFDKVRKALRSAEAY

SIN3A

466

Q96ST3
FVVDCEFFKKEKRYI

PGAP1

451

Q75T13
RDDACTRKFYFFVAI

SLCO1B1

526

Q9Y6L6
NSFDCFKKVLRYEGF

SLC25A12

371

O75746
RCFVKVRAYANDKFT

CILP2

736

Q8IUL8
DDIDFDVYFRKTKAA

NCAPH

476

Q15003
CAKVVDKSEYRTFAA

NCAPD3

361

P42695
REREFVYKFKVGSQC

C12orf4

11

Q9NQ89
LIFARKDTFFKDVDY

CNDP2

176

Q96KP4
KDTFFKDVDYVCISD

CNDP2

181

Q96KP4
KYAFFECKRSVLDNR

COA5

51

Q86WW8
YKCEECDEAFRFKSS

ZNF525

411

Q8N782
FCRDEKGERVDVSKY

RNF17

1081

Q9BXT8
ADITEDEFKRLFAKY

SFPQ

306

P23246
AFDFDRYKQRCAELK

ZC3HC1

131

Q86WB0
EKEFNFLDYLKRFAC

TIMELESS

686

Q9UNS1
DRCLFYYKDEKEESI

PLEKHA6

86

Q9Y2H5
AFDFCSFLIAEKLVK

UGT3A1

146

Q6NUS8
YFARKEEDCKEYVAA

VPS11

726

Q9H270
ELSYRAREIFSKFLC

RGS12

761

O14924
TDCSRVFKQFKYLSV

RLF

676

Q13129
AYFRLKKFAVAESDC

RPAP3

176

Q9H6T3
CEKCDKVFKRFSYLT

ZNF682

371

O95780
KSLDKCDFTEIHRYF

TOP1MT

131

Q969P6
VLTYDFTNCDFEKIK

TSLP

26

Q969D9
VVCYDDRFIVKLAFD

ZC3H12B

276

Q5HYM0
TDICKFFLKVSELFD

SNX6

261

Q9UNH7
GEKAYECAKFEKIFT

ZNF585A

126

Q6P3V2
TYCEIDLDKEKRDAF

TM9SF3

106

Q9HD45
IYEVCKSKDSRNADF

TOPAZ1

1001

Q8N9V7
ERVFKCDICSKTFKY

ZNF251

206

Q9BRH9
EDFKECFSAYKRENR

ZSWIM3

11

Q96MP5
ISEKSFEYKECGIDF

ZNF420

666

Q8TAQ5
IDFFKERAKLACFDS

SLC9C2

876

Q5TAH2
AAFRKQNYLEEKVCF

TASOR2

71

Q5VWN6
DSVKITFKCETEYAF

TASOR2

741

Q5VWN6
CKSTFLFYLVETEDK

TASOR2

2181

Q5VWN6
KAVDYIEKALEYFTC

TTC37

691

Q6PGP7
VKVDYKSIFDRRCAE

SORCS1

661

Q8WY21
EYDEKARLCLFGSSK

TUT4

986

Q5TAX3
LSAFYDVDFLCKTEK

ZFP36L2

6

P47974
FLKEEKLEGDNRYFC

USP48

256

Q86UV5
SELAKKEEEAYFERC

PRPF18

31

Q99633
TCFKAAFLDFKDLLE

TEX19

36

Q8NA77
FSELKFYQRVAKKDC

VRK2

71

Q86Y07
RKLVEYLKESCFDAV

UGT1A7

131

Q9HAW7
FTDECVKKYEAFLNK

TBK1

601

Q9UHD2
RCEYEDTHKAFAKAF

PP2D1

276

A8MPX8
ARFDFKKCKLLYESF

VPS13D

2311

Q5THJ4
DTEKSRFFRFCVAIK

VPS13D

3136

Q5THJ4
DSLTDEIKFFKCLYE

KRT72

251

Q14CN4
FADKVEYKCEGFLEK

MYO5C

551

Q9NQX4
YKDKFDSCSFDLEVH

MYBPC1

146

Q00872
YEVAVKDEKCFTELF

MYBPC2

326

Q14324