Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
HumanPheno	Intellectual disability, mild	SLC29A3 L1CAM APC2 GLIS3 DCC SRCAP ZNF462 KMT2D KANSL1 AP5Z1 ASCC3 GTPBP3	2.36e-05	365	42	12	HP:0001256
HumanPheno	Abnormal corpus callosum morphology	AIMP2 HCN1 IQSEC2 L1CAM APC2 RTTN TSEN54 HUWE1 DCC ZNF462 FCSK KMT2D KANSL1 PIK3R2 AP5Z1 BRD4 BRPF1 CFC1 SPEN	5.49e-05	937	42	19	HP:0001273
HumanPheno	Aplasia/Hypoplasia of the corpus callosum	AIMP2 IQSEC2 L1CAM APC2 RTTN TSEN54 HUWE1 DCC ZNF462 FCSK KMT2D KANSL1 PIK3R2 AP5Z1 BRD4 CFC1 SPEN	5.96e-05	772	42	17	HP:0007370
HumanPheno	Thin corpus callosum	AIMP2 IQSEC2 L1CAM APC2 RTTN TSEN54 HUWE1 DCC ZNF462 FCSK KMT2D KANSL1 PIK3R2 AP5Z1 BRD4 BRPF1 CFC1 SPEN	7.24e-05	868	42	18	HP:0033725
HumanPheno	Anteverted nares	DOCK3 SLC29A3 AIMP2 IQSEC2 HUWE1 SRCAP TUBGCP6 ZNF462 KMT2D BRD4 MESP2 ASCC3 SPEN GNS	8.88e-05	559	42	14	HP:0000463
HumanPheno	Upturned nose	DOCK3 SLC29A3 AIMP2 IQSEC2 HUWE1 SRCAP TUBGCP6 ZNF462 KMT2D BRD4 MESP2 ASCC3 SPEN GNS	8.88e-05	559	42	14	HP:0000427
HumanPheno	Abnormal morphology of the nasal alae	DOCK3 SLC29A3 AIMP2 IQSEC2 HUWE1 SRCAP TUBGCP6 ZNF462 KMT2D KANSL1 BRD4 MESP2 ASCC3 SPEN GNS	9.57e-05	639	42	15	HP:0000429
HumanPheno	Abnormal nostril morphology	DOCK3 SLC29A3 AIMP2 IQSEC2 HUWE1 SRCAP TUBGCP6 ZNF462 KMT2D BRD4 MESP2 ASCC3 SPEN GNS	1.21e-04	575	42	14	HP:0005288
Domain	CFC	CFC1 CFC1B	1.26e-04	3	122	2	PF09443
Domain	Cryptic/Cripto_CFC-dom	CFC1 CFC1B	1.26e-04	3	122	2	IPR019011
Domain	Ion_trans_N	HCN1 HCN3	2.52e-04	4	122	2	IPR013621
Domain	FAM47	FAM47A FAM47C	2.52e-04	4	122	2	PF14642
Domain	Ion_trans_N	HCN1 HCN3	2.52e-04	4	122	2	PF08412
Domain	FAM47	FAM47A FAM47C	2.52e-04	4	122	2	IPR032743
Domain	ARM-type_fold	DCAF1 DOCK3 USP34 CAND2 APC2 RTTN RICTOR HUWE1 UPF2	3.89e-04	339	122	9	IPR016024
Domain	Liprin	PPFIA4 PPFIA1	6.24e-04	6	122	2	IPR029515
Domain	EPL1	BRPF1 EPC1	1.15e-03	8	122	2	PF10513
Domain	Enhancer_polycomb-like_N	BRPF1 EPC1	1.15e-03	8	122	2	IPR019542
Domain	CNMP_BINDING_1	HCN1 HCN3 RAPGEF3	1.17e-03	32	122	3	PS00888
Domain	CNMP_BINDING_2	HCN1 HCN3 RAPGEF3	1.17e-03	32	122	3	PS00889
Domain	cNMP	HCN1 HCN3 RAPGEF3	1.40e-03	34	122	3	SM00100
Domain	cNMP_binding	HCN1 HCN3 RAPGEF3	1.40e-03	34	122	3	PF00027
Domain	cNMP-bd_dom	HCN1 HCN3 RAPGEF3	1.53e-03	35	122	3	IPR000595
Domain	CNMP_BINDING_3	HCN1 HCN3 RAPGEF3	1.53e-03	35	122	3	PS50042
Domain	cNMP-bd-like	HCN1 HCN3 RAPGEF3	1.94e-03	38	122	3	IPR018490
Domain	ARM-like	DCAF1 CAND2 APC2 RTTN RICTOR HUWE1 AP5Z1	1.99e-03	270	122	7	IPR011989
Domain	-	DCAF1 CAND2 APC2 RTTN RICTOR AP5Z1	3.39e-03	222	122	6	1.25.10.10
Domain	Ras_G-nucl-exch_fac_CS	RASGRF2 RAPGEF3	3.66e-03	14	122	2	IPR019804
Domain	K_chnl_volt-dep_EAG/ELK/ERG	HCN1 HCN3	3.66e-03	14	122	2	IPR003938
Domain	-	HCN1 HCN3 RAPGEF3	3.80e-03	48	122	3	2.60.120.10
Domain	RmlC-like_jellyroll	HCN1 HCN3 RAPGEF3	4.51e-03	51	122	3	IPR014710
Domain	Post-SET_dom	KMT2D EHMT2	4.78e-03	16	122	2	IPR003616
Domain	PostSET	KMT2D EHMT2	4.78e-03	16	122	2	SM00508
Domain	Sulfatase_CS	ARSD GNS	4.78e-03	16	122	2	IPR024607
Domain	POST_SET	KMT2D EHMT2	4.78e-03	16	122	2	PS50868
Domain	SULFATASE_1	ARSD GNS	5.40e-03	17	122	2	PS00523
Domain	SULFATASE_2	ARSD GNS	5.40e-03	17	122	2	PS00149
Domain	SH2	CBLC PIK3R2 FES TNS1	5.88e-03	110	122	4	SM00252
Domain	Sulfatase	ARSD GNS	6.05e-03	18	122	2	PF00884
Domain	Sulfatase_N	ARSD GNS	6.05e-03	18	122	2	IPR000917
Domain	SH2	CBLC PIK3R2 FES TNS1	6.07e-03	111	122	4	PS50001
Domain	SH2	CBLC PIK3R2 FES TNS1	6.26e-03	112	122	4	IPR000980
Domain	-	CBLC PIK3R2 FES TNS1	6.26e-03	112	122	4	3.30.505.10
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DOCK3 SEMA3F USP34 SRXN1 MFHAS1 CDK12 L1CAM RTTN CBLC HUWE1 EDC4 SRCAP KIFC2 ZCCHC14 KMT2D KANSL1 BRD4 IRS2 DOT1L DMWD SPEN SOWAHB MVB12B	1.37e-11	1105	127	23	35748872
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TRERF1 USP34 PPFIA1 CAMSAP3 MCCC1 HUWE1 ZNF462 KMT2D EHMT2 ANAPC1 BRD4 IRS2 ASCC3	5.00e-09	418	127	13	34709266
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	TRERF1 DCAF1 USP34 GLIS3 ZNF462 INTS14 EHMT2 ANAPC1 ASCC3 SPEN	9.51e-08	282	127	10	23667531
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DCAF1 USP34 IL16 PPFIA1 EMILIN3 RICTOR SRCAP TUBGCP6 FCSK INTS14 EHMT2 ANAPC1 PIK3R2 BRD4 BRPF1 EPC1 IRS2 ASCC3	1.37e-07	1116	127	18	31753913
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TRERF1 CDK12 CAMSAP3 CBLC RICTOR HUWE1 TUBGCP6 KMT2D KANSL1 ANAPC1 BRD4 BRPF1 IRS2 DMWD SPEN	1.65e-07	774	127	15	15302935
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TRERF1 NHSL2 HCN1 PPFIA1 IQSEC2 HCN3 APC2 CAMSAP3 HUWE1 EDC4 SHISA7 ZNF462 EHMT2 ANAPC1 TNS1	2.52e-06	963	127	15	28671696
Pubmed	Satb2 Regulates the Differentiation of Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex.	HCN1 L1CAM CRYM	1.02e-05	12	127	3	25037921
Pubmed	Repurposing of the enhancer-promoter communication underlies the compensation of Mesp2 by Mesp1.	MESP1 MESP2	1.32e-05	2	127	2	35025872
Pubmed	The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.	CFC1 CFC1B	1.32e-05	2	127	2	11174844
Pubmed	Estrogen receptor β controls MMP-19 expression in mouse ovaries during ovulation.	ESR2 MMP19	1.32e-05	2	127	2	26700939
Pubmed	HCN3 contributes to the ventricular action potential waveform in the murine heart.	HCN1 HCN3	1.32e-05	2	127	2	21903939
Pubmed	mTORC2 regulates auditory hair cell structure and function.	RICTOR MYO15A	1.32e-05	2	127	2	37694145
Pubmed	Transcriptional regulation of Mesp1 and Mesp2 genes: differential usage of enhancers during development.	MESP1 MESP2	1.32e-05	2	127	2	11578861
Pubmed	The roles of Mesp family proteins: functional diversity and redundancy in differentiation of pluripotent stem cells and mammalian mesodermal development.	MESP1 MESP2	1.32e-05	2	127	2	26088191
Pubmed	Functional interdependence of BRD4 and DOT1L in MLL leukemia.	BRD4 DOT1L	1.32e-05	2	127	2	27294782
Pubmed	IL16 and factor V gene variations are associated with asparaginase-related thrombosis in childhood acute lymphoblastic leukemia patients.	IL16 F5	1.32e-05	2	127	2	36946317
Pubmed	A nuclear complex of rictor and insulin receptor substrate-2 is associated with albuminuria in diabetic mice.	RICTOR IRS2	1.32e-05	2	127	2	20545557
Pubmed	Identification of differentially expressed genes in mouse development using differential display and in situ hybridization.	CFC1 CFC1B	1.32e-05	2	127	2	11327798
Pubmed	Subtractive hybridization identifies chick-cripto, a novel EGF-CFC ortholog expressed during gastrulation, neurulation and early cardiogenesis.	CFC1 CFC1B	1.32e-05	2	127	2	11024280
Pubmed	Identification of presomitic mesoderm (PSM)-specific Mesp1 enhancer and generation of a PSM-specific Mesp1/Mesp2-null mouse using BAC-based rescue technology.	MESP1 MESP2	1.32e-05	2	127	2	18328678
Pubmed	Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects.	CFC1 CFC1B	1.32e-05	2	127	2	11062482
Pubmed	Impact of WIN site inhibitor on the WDR5 interactome.	RICTOR ZNF462 KMT2D KANSL1	1.87e-05	43	127	4	33472061
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	CDK12 HUWE1 EDC4 SRCAP KMT2D ANAPC1 BRD4 DOT1L ASCC3 SPEN	3.56e-05	549	127	10	38280479
Pubmed	Draxin inhibits axonal outgrowth through the netrin receptor DCC.	L1CAM DCC	3.96e-05	3	127	2	21957262
Pubmed	IRS-4 mediates protein kinase B signaling during insulin stimulation without promoting antiapoptosis.	PIK3R2 IRS2	3.96e-05	3	127	2	10594015
Pubmed	Cooperative Mesp activity is required for normal somitogenesis along the anterior-posterior axis.	MESP1 MESP2	3.96e-05	3	127	2	16996494
Pubmed	Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells.	PIK3R2 IRS2	3.96e-05	3	127	2	9651378
Pubmed	Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs.	CFC1 CFC1B	3.96e-05	3	127	2	16835440
Pubmed	mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis.	RICTOR PARD6A	3.96e-05	3	127	2	20978191
Pubmed	A family of hyperpolarization-activated mammalian cation channels.	HCN1 HCN3	3.96e-05	3	127	2	9634236
Pubmed	Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.	CBLC RICTOR PIK3R2	4.41e-05	19	127	3	31959764
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	USP34 SRXN1 CAND2 GAS2L3 PPFIA1 RICTOR HUWE1 SRCAP KIFC2 INTS14 DOT1L DMWD TNS1 SLX4	4.43e-05	1084	127	14	11544199
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	SLC29A3 RICTOR DCC TUBGCP6 FCSK FBXL7 PLEKHG6 PARD6A ANAPC1 SLMAP MYO15A MVB12B	4.59e-05	814	127	12	23251661
Pubmed	Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.	CDK12 ESR2 XRCC3 EHMT2 STARD3	7.25e-05	117	127	5	19124506
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MIIP PPFIA1 IQSEC2 CAMSAP3 RICTOR MCCC1 EDC4 MEX3C ZCCHC14 BRD4 IRS2 SH3RF3	7.83e-05	861	127	12	36931259
Pubmed	Functional expression of the human HCN3 channel.	HCN1 HCN3	7.90e-05	4	127	2	16043489
Pubmed	Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels.	HCN1 HCN3	7.90e-05	4	127	2	9405696
Pubmed	Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels.	HCN1 HCN3	7.90e-05	4	127	2	12928435
Pubmed	Cripto in tumors and embryo development.	CFC1 CFC1B	7.90e-05	4	127	2	11825688
Pubmed	Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice.	HCN1 HCN3	7.90e-05	4	127	2	20140458
Pubmed	Investigation of hyperpolarization-activated cyclic nucleotide-gated channels in interstitial cells of Cajal of human bladder.	HCN1 HCN3	7.90e-05	4	127	2	22748890
Pubmed	How SLX4 cuts through the mystery of HIV-1 Vpr-mediated cell cycle arrest.	DCAF1 SLX4	7.90e-05	4	127	2	25496524
Pubmed	Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain.	HCN1 HCN3	7.90e-05	4	127	2	9630217
Pubmed	Loss of Dcc in the spinal cord is sufficient to cause a deficit in lateralized motor control and the switch to a hopping gait.	L1CAM DCC	7.90e-05	4	127	2	28691197
Pubmed	Role of the EGF-CFC gene cripto in cell differentiation and embryo development.	CFC1 CFC1B	7.90e-05	4	127	2	11992720
Pubmed	Aberrant development of hippocampal circuits and altered neural activity in netrin 1-deficient mice.	L1CAM DCC	7.90e-05	4	127	2	11044395
Pubmed	Increased expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in reactive astrocytes following ischemia.	HCN1 HCN3	7.90e-05	4	127	2	25042871
Pubmed	Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons.	HCN1 HCN3	7.90e-05	4	127	2	26966193
Pubmed	Genetic analysis of hyperpolarization-activated cyclic nucleotide-gated cation channels in sudden unexpected death in epilepsy cases.	HCN1 HCN3	7.90e-05	4	127	2	21615589
Pubmed	A Genome-Wide Screen for Machinery Involved in Downregulation of MHC Class I by HIV-1 Nef.	MIIP CAMSAP3	7.90e-05	4	127	2	26466362
Pubmed	Specific arrest of cardiogenesis in cultured embryonic stem cells lacking Cripto-1.	CFC1 CFC1B	7.90e-05	4	127	2	9576836
Pubmed	Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease.	HCN1 HCN3	7.90e-05	4	127	2	21233488
Pubmed	Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds.	FAM90A14 FAM90A22 FAM90A23	7.98e-05	23	127	3	18602769
Pubmed	Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events.	FAM90A14 FAM90A22 FAM90A23	1.03e-04	25	127	3	17684299
Pubmed	Biological insights from 108 schizophrenia-associated genetic loci.	HCN1 EDC4 XRCC3 PARD6A GID4 FES MYO15A	1.30e-04	303	127	7	25056061
Pubmed	Viral delivery of L1CAM promotes axonal extensions by embryonic cerebral grafts in mouse brain.	L1CAM DCC	1.31e-04	5	127	2	36963389
Pubmed	Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction.	HCN1 HCN3	1.31e-04	5	127	2	15564593
Pubmed	The phosphotyrosine interactome of the insulin receptor family and its substrates IRS-1 and IRS-2.	INSRR IRS2	1.31e-04	5	127	2	19001411
Pubmed	A differential display strategy identifies Cryptic, a novel EGF-related gene expressed in the axial and lateral mesoderm during mouse gastrulation.	CFC1 CFC1B	1.31e-04	5	127	2	9053319
Pubmed	Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm-specific enhancer of Mesp2.	MESP1 MESP2	1.31e-04	5	127	2	18849530
Pubmed	Netrin-1 and DCC mediate axon guidance locally at the optic disc: loss of function leads to optic nerve hypoplasia.	L1CAM DCC	1.31e-04	5	127	2	9331350
Pubmed	Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice.	HCN1 HCN3	1.31e-04	5	127	2	34429357
Pubmed	The mouse and human Liprin-alpha family of scaffolding proteins: genomic organization, expression profiling and regulation by alternative splicing.	PPFIA4 PPFIA1	1.31e-04	5	127	2	19013515
Pubmed	Functional coupling of Tmem74 and HCN1 channels regulates anxiety-like behavior in BLA neurons.	HCN1 HCN3	1.31e-04	5	127	2	30886335
Pubmed	SPOP mutation induces DNA methylation via stabilizing GLP/G9a.	EHMT2 BRD4	1.31e-04	5	127	2	34588438
Pubmed	G2/M cell cycle arrest correlates with primate lentiviral Vpr interaction with the SLX4 complex.	DCAF1 SLX4	1.31e-04	5	127	2	25320300
Pubmed	Self-regulated left-right asymmetric expression of Pitx2c in the developing mouse limb.	CFC1 CFC1B	1.31e-04	5	127	2	25224222
Pubmed	Differential contributions of Mesp1 and Mesp2 to the epithelialization and rostro-caudal patterning of somites.	MESP1 MESP2	1.31e-04	5	127	2	15677726
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP34 CAND2 CDK12 KIAA1614 TUBGCP6 ST6GAL2 FBXL7 AP5Z1 SLMAP	1.48e-04	529	127	9	14621295
Pubmed	Netrin-1 promotes thalamic axon growth and is required for proper development of the thalamocortical projection.	L1CAM DCC	1.97e-04	6	127	2	10908620
Pubmed	An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses.	DCAF1 CBLC	1.97e-04	6	127	2	30118682
Pubmed	A role of the cryptic gene in the correct establishment of the left-right axis.	CFC1 CFC1B	1.97e-04	6	127	2	10574770
Pubmed	Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway.	CFC1 CFC1B	1.97e-04	6	127	2	12052855
Pubmed	MesP1: a novel basic helix-loop-helix protein expressed in the nascent mesodermal cells during mouse gastrulation.	MESP1 FES	1.97e-04	6	127	2	8787751
Pubmed	SLX4-SLX1 Protein-independent Down-regulation of MUS81-EME1 Protein by HIV-1 Viral Protein R (Vpr).	DCAF1 SLX4	1.97e-04	6	127	2	27354282
Pubmed	The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance.	L1CAM APLP2	1.97e-04	6	127	2	28785723
Pubmed	Ventral midline cells are required for the local control of commissural axon guidance in the mouse spinal cord.	L1CAM DCC	1.97e-04	6	127	2	10409510
Pubmed	GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.	CFC1 CFC1B	1.97e-04	6	127	2	17991893
Pubmed	Analyses of the spatiotemporal expression and subcellular localization of liprin-α proteins.	PPFIA4 PPFIA1	1.97e-04	6	127	2	21618221
Pubmed	Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling.	RASIP1 RAPGEF3	1.97e-04	6	127	2	23886837
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	DOCK3 PPFIA4 KIFC2 EHMT2 BRD4 SPEN GNS	2.16e-04	329	127	7	17474147
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	USP34 IL16 INSRR CAMSAP3 RICTOR SHISA7 GPR179 IRS2 ASCC3 SLX4 MVB12B	2.47e-04	832	127	11	36724073
Pubmed	Defects in neural guidepost structures and failure to remove leptomeningeal cells from the septal midline behind the interhemispheric fusion defects in Netrin1 deficient mice.	L1CAM DCC	2.75e-04	7	127	2	26397040
Pubmed	PlexinA1 is crucial for the midline crossing of callosal axons during corpus callosum development in BALB/cAJ mice.	L1CAM DCC	2.75e-04	7	127	2	31430342
Pubmed	LPCAT3 Is Transcriptionally Regulated by YAP/ZEB/EP300 and Collaborates with ACSL4 and YAP to Determine Ferroptosis Sensitivity.	KMT2D EHMT2	2.75e-04	7	127	2	37166352
Pubmed	Evidence for topographic guidance of dopaminergic axons by differential Netrin-1 expression in the striatum.	L1CAM DCC	2.75e-04	7	127	2	24867253
Pubmed	Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation.	CFC1 CFC1B	2.75e-04	7	127	2	10521397
Pubmed	Interaction between GRIP and liprin-alpha/SYD2 is required for AMPA receptor targeting.	PPFIA4 PPFIA1	2.75e-04	7	127	2	11931740
Pubmed	IL-4/IL-13 signaling beyond JAK/STAT.	FES IRS2	2.75e-04	7	127	2	10856136
Pubmed	From arrest to escape: HIV-1 Vpr cuts a deal.	DCAF1 SLX4	2.75e-04	7	127	2	24528857
Pubmed	Transcription profiling of HCN-channel isotypes throughout mouse cardiac development.	HCN1 HCN3	2.75e-04	7	127	2	19421833
Pubmed	Reversal of left-right asymmetry induced by aberrant Nodal signaling in the node of mouse embryos.	CFC1 CFC1B	2.75e-04	7	127	2	19906859
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	SRCAP KMT2D EHMT2 BRPF1 EPC1	2.87e-04	157	127	5	30186101
Pubmed	Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects.	MESP1 CFC1 CFC1B	3.11e-04	36	127	3	27606604
Pubmed	Interaction network of human early embryonic transcription factors.	TRERF1 ZNF462 KMT2D EHMT2 EPC1 SPEN SLX4	3.19e-04	351	127	7	38297188
Pubmed	The genetic architecture of economic and political preferences.	FBXL7 EHMT2 ASCC3	3.37e-04	37	127	3	22566634
Pubmed	The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development.	SEMA3F L1CAM	3.65e-04	8	127	2	25953347
Pubmed	Left-right asymmetry in the level of active Nodal protein produced in the node is translated into left-right asymmetry in the lateral plate of mouse embryos.	CFC1 CFC1B	3.65e-04	8	127	2	21419113
Pubmed	Topography of thalamic projections requires attractive and repulsive functions of Netrin-1 in the ventral telencephalon.	L1CAM DCC	3.65e-04	8	127	2	18479186
Pubmed	Temporal regulation of axonal repulsion by alternative splicing of a conserved microexon in mammalian Robo1 and Robo2.	L1CAM DCC	3.65e-04	8	127	2	31392959
Interaction	CYP4X1 interactions	PPFIA1 PLEKHA4 CYP4X1	8.84e-07	4	123	3	int:CYP4X1
Interaction	TOP3B interactions	DOCK3 SEMA3F USP34 SRXN1 MFHAS1 CDK12 L1CAM RTTN PLEKHA4 CBLC HUWE1 EDC4 SRCAP KIFC2 ZCCHC14 KMT2D KANSL1 UPF2 BRD4 IRS2 DOT1L DMWD SPEN SOWAHB MVB12B	2.40e-06	1470	123	25	int:TOP3B
Interaction	BUB3 interactions	AIMP2 ESR2 PLEKHA4 HUWE1 RASIP1 KMT2D KANSL1 BRD4 SLX4	1.28e-05	232	123	9	int:BUB3
Interaction	INTS8 interactions	ESR2 PLEKHA4 GLMP INTS14 DOT1L	3.82e-05	62	123	5	int:INTS8
Interaction	BCAS2 interactions	MIIP AIMP2 CDK12 ESR2 PLEKHA4 EMILIN3 BRD4 DOT1L SPEN	4.23e-05	270	123	9	int:BCAS2
Interaction	RCOR1 interactions	USP34 ESR2 PPFIA1 CAMSAP3 MCCC1 HUWE1 KMT2D EHMT2 ANAPC1 BRD4 ASCC3 SPEN	5.05e-05	494	123	12	int:RCOR1
Interaction	IK interactions	CDK12 ESR2 RICTOR SRCAP BRD4 DOT1L SPEN SLX4	5.31e-05	215	123	8	int:IK
Interaction	MRGBP interactions	MFHAS1 ESR2 PLEKHA4 SRCAP BRD4 EPC1	5.54e-05	109	123	6	int:MRGBP
Interaction	KDM1A interactions	TRERF1 USP34 IL16 ESR2 PPFIA1 CAMSAP3 PLEKHA4 MCCC1 HUWE1 ZNF462 KMT2D KANSL1 EHMT2 ANAPC1 BRD4 IRS2 ASCC3	5.81e-05	941	123	17	int:KDM1A
Interaction	ZNF462 interactions	DCAF1 ZNF462 EHMT2 DOT1L SLX4	5.98e-05	68	123	5	int:ZNF462
Interaction	NCCRP1 interactions	HCN1 ESR2 RICTOR MCCC1 FES SLX4	6.14e-05	111	123	6	int:NCCRP1
Interaction	INF2 interactions	USP34 ESR2 PLEKHA4 RICTOR XRCC3 TUBGCP6 FCSK INTS14 ASCC3	6.96e-05	288	123	9	int:INF2
Interaction	SMU1 interactions	CDK12 ESR2 RICTOR HUWE1 RNF157 BRD4 DOT1L SPEN	7.76e-05	227	123	8	int:SMU1
Interaction	B4GALT2 interactions	USP34 RICTOR TUBGCP6 FCSK ANAPC1 ASCC3	9.04e-05	119	123	6	int:B4GALT2
Cytoband	12q14	MMP19 GNS	4.11e-04	11	127	2	12q14
Cytoband	15q26.1	MESP1 FES MESP2	4.63e-04	54	127	3	15q26.1
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2D EHMT2 DOT1L	4.04e-04	34	77	3	487
GeneFamily	Cyclic nucleotide gated channels	HCN1 HCN3	7.88e-04	10	77	2	250
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASGRF2 PLEKHA4 PLEKHA6 PLEKHG6 IRS2	1.86e-03	206	77	5	682
GeneFamily	Sulfatases	ARSD GNS	2.62e-03	18	77	2	410
Coexpression	GSE14350_TREG_VS_TEFF_DN	SEMA3F SRXN1 HCN3 INSRR CBLC FBXL7 FES SOWAHB	5.16e-06	200	124	8	M3418
Coexpression	JAZAG_TGFB1_SIGNALING_UP	MRPS31 L1CAM SRCAP TGM5 EHMT2 RAPGEF3	1.15e-05	106	124	6	M7160
ToppCell	Cerebellum-Neuronal\|Cerebellum / BrainAtlas - Mouse McCarroll V32	HCN1 L1CAM HCN3 TMEM151B TUBGCP6 ST6GAL2 CYP4X1	9.57e-07	187	124	7	61b9d6eb131a674598aa8409d7fa909c8765442d
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	SEMA3F RASGRF2 RASIP1 FBXL7 RAPGEF3 NEURL1B SH3RF3	9.91e-07	188	124	7	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	SEMA3F RASGRF2 NHSL2 RASIP1 FBXL7 NEURL1B SH3RF3	1.40e-06	198	124	7	8689090bce9ab6e8f122426a404037e572c6713b
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PLEKHA4 PKDCC EMILIN3 KCNIP2 SNED1 ADAMTS14 NEURL1B	1.45e-06	199	124	7	fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RASGRF2 NHSL2 PLEKHA4 PKDCC EMILIN3 SNED1 NEURL1B	1.45e-06	199	124	7	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RASGRF2 NHSL2 PLEKHA4 PKDCC EMILIN3 SNED1 NEURL1B	1.45e-06	199	124	7	9c2db0bb94cba71a3cc1827844da090e213e0258
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	RASGRF2 NHSL2 LRTM1 PLEKHA4 PKDCC KIAA1614 FBXL7	1.50e-06	200	124	7	24e13b6d9d2d8b29df1f02544ea9c50084d9e75c
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	RASGRF2 NHSL2 LRTM1 PLEKHA4 PKDCC KIAA1614 FBXL7	1.50e-06	200	124	7	f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRTM1 PLEKHA4 PKDCC ST6GAL2 CRYM WT1-AS	9.39e-06	174	124	6	4da79da7a09ee1e345102c5331675ebcdbe56171
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 GAS2L3 L1CAM CAMSAP3 INTS14 MVB12B	1.14e-05	180	124	6	da723df348d7b8449bb1124f23fe6fa706412adb
ToppCell	droplet-Heart-nan-3m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 GAS2L3 L1CAM CAMSAP3 INTS14 MVB12B	1.14e-05	180	124	6	5b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 GAS2L3 L1CAM CAMSAP3 INTS14 MVB12B	1.14e-05	180	124	6	50758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 SNED1 RASIP1 FBXL7 NEURL1B SH3RF3	1.29e-05	184	124	6	688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 SNED1 RASIP1 FBXL7 NEURL1B SH3RF3	1.41e-05	187	124	6	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F RASGRF2 APLP2 RASIP1 RAPGEF3 TNS1	1.55e-05	190	124	6	38a815abf0ac5cac6071737cadc54a514f62d37d
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F RASGRF2 APLP2 RASIP1 RAPGEF3 TNS1	1.55e-05	190	124	6	bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F RASGRF2 APLP2 RASIP1 RAPGEF3 TNS1	1.55e-05	190	124	6	d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCell	COVID-19-kidney-VWF+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RASGRF2 RASIP1 FBXL7 NEURL1B TNS1 SH3RF3	1.59e-05	191	124	6	2f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 PKDCC SNED1 FBXL7 NEURL1B SH3RF3	1.79e-05	195	124	6	d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell	COVID-19-kidney-VWF+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	RASGRF2 SNED1 RASIP1 FBXL7 NEURL1B SH3RF3	1.85e-05	196	124	6	b71b197cb92117dd9efaa13de000841901cc4ca8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 SNED1 RASIP1 FBXL7 NEURL1B SH3RF3	1.90e-05	197	124	6	0f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell	PBMC-Severe-cDC_2\|Severe / Compartment, Disease Groups and Clusters	RASGRF2 HCN3 GLIS3 CRYM	4.14e-05	69	124	4	0fab02d29408415d3aa1f42a55a2e37b458c4030
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	SEMA3F TESMIN PIK3R2 NEURL1B FBXO27	5.55e-05	146	124	5	5b2608b56204dda9a773988f42ff00a9fa743a39
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Cpne7\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	IL16 DCC CRYM PLEKHG6 RAPGEF3	6.11e-05	149	124	5	8638b3819193d11411df58964069fec583f617f4
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-NP\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	IL16 GAS2L3 DCC CRYM PLEKHG6	6.71e-05	152	124	5	b6a7453fbf9f898e4f222b215907c9a110baa2f6
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MFHAS1 PKDCC ARSD PIK3R2 SLX4	7.82e-05	157	124	5	4766f7d545bf2d775390589460677519cb92f4d5
ToppCell	facs-Marrow-T-cells-24m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQSEC2 RICTOR PGLYRP2 XRCC3 GID4	8.55e-05	160	124	5	b3f7ef7e682b48a83ca425f5c439336e96168300
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	SRXN1 OOEP FOXRED2 INTS14 RAPGEF3	9.61e-05	164	124	5	d7053de88ef8e42cac6726a40e72f212659ee034
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC29A3 NHSL2 PPFIA4 F5 DOT1L	1.02e-04	166	124	5	de319c960b0cd90b294f677d1ea1b013a2ce2d53
ToppCell	NS-critical-d_0-4-Epithelial-unknown_epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	HCN3 PLEKHA4 PLEKHA6 FBXL7 GID4	1.02e-04	166	124	5	dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DOCK3 PLEKHA6 RNF157 PLEKHG6 MYO15A	1.08e-04	168	124	5	de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell	COVID-19_Mild-PLT_2\|World / Disease Group and Platelet Clusters	PGLYRP2 MCCC1 KCNIP2 RNF157 BRPF1	1.11e-04	169	124	5	6abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GLIS3 EMILIN3 ADAMTS14 MMP19 SH3RF3	1.11e-04	169	124	5	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CAMSAP3 CBLC KIFC2 TESMIN SLX4	1.14e-04	170	124	5	330b5fc8fde307eda9dcc7bc9053ea8a7e1f0f6d
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CAMSAP3 CBLC KIFC2 TESMIN SLX4	1.14e-04	170	124	5	0c9d38e89b048166b879e6b4bdf7c5dfe8ab57c4
ToppCell	facs-BAT-Fat-3m-Myeloid-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NHSL2 PPFIA4 F5 FES STARD3	1.20e-04	172	124	5	5f18c3f8eb8b7928901eede44c9b84b3c5efa1a9
ToppCell	COVID-19_Mild-PLT_2\|COVID-19_Mild / Disease Group and Platelet Clusters	PGLYRP2 MCCC1 KCNIP2 F5 BRPF1	1.23e-04	173	124	5	d11705e56b6b21eec963ea224717f27680c781ed
ToppCell	COVID-19-kidney-REN+Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRERF1 PPFIA4 DCC RAPGEF3 PIP5K1B	1.27e-04	174	124	5	8393f0b43c767839c1630bcb952d62b42efc788d
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DCAF1 CAND2 TESMIN EPC1 NEURL1B	1.30e-04	175	124	5	bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCell	BAL-Control-cDC_11\|Control / Compartment, Disease Groups and Clusters	RASGRF2 PGLYRP2 RNF157 ZNF462 FBXO27	1.30e-04	175	124	5	daf014e15a354956e9149c83fd89d0af0d07eb00
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	L1CAM TESMIN PARD6A EPC1 DMWD	1.30e-04	175	124	5	bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell	wk_20-22-Epithelial-PNS-Late_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GAS2L3 L1CAM APC2 PLEKHA4 KCNIP2	1.34e-04	176	124	5	81924471d8a8c5bd8eedf294c007e25b6cd3e417
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NHSL2 ATP10D FBXL7 MMP19	1.34e-04	176	124	5	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NHSL2 ATP10D FBXL7 MMP19	1.34e-04	176	124	5	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IL16 RASGRF2 MFHAS1 RICTOR KIFC2	1.45e-04	179	124	5	6bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	DOCK3 ESR2 FBXL7 STARD3 SH3RF3	1.45e-04	179	124	5	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3F RASGRF2 RASIP1 TNS1 SH3RF3	1.49e-04	180	124	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	RA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	INSRR GLIS3 PKDCC FBXL7 MMP19	1.52e-04	181	124	5	2b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	SEMA3F RASGRF2 FBXL7 NEURL1B SH3RF3	1.52e-04	181	124	5	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MFHAS1 LRTM1 SNED1 ST6GAL2 SLMAP	1.56e-04	182	124	5	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	droplet-Lung-LUNG-1m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CBLC OOEP SHISA7 PIP5K1B MESP2	1.56e-04	182	124	5	c1e0be27064e14043b78ae501b02d4e9542267a3
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INSRR XRCC3 KCNIP2 F5 KMT2D	1.56e-04	182	124	5	1923932a9c60e9ec33db69ded441210d1fb07bec
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INSRR XRCC3 KCNIP2 F5 KMT2D	1.56e-04	182	124	5	69ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCell	droplet-Lung-LUNG-1m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CBLC OOEP SHISA7 PIP5K1B MESP2	1.56e-04	182	124	5	3c9b4869d357884ae4bcd22a9872faf83a5cfc6d
ToppCell	COVID-19-kidney-Mito-rich_EC\|kidney / Disease (COVID-19 only), tissue and cell type	NHSL2 RASIP1 FBXL7 NEURL1B SH3RF3	1.60e-04	183	124	5	3c4153479fc4ab2d073d92cee120480015555914
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRERF1 DOCK3 DCC SNED1 ST6GAL2	1.60e-04	183	124	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RASGRF2 RASIP1 FBXL7 NEURL1B SH3RF3	1.60e-04	183	124	5	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	wk_20-22-Epithelial-PNS-intermediate_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GAS2L3 L1CAM PLEKHA4 MESP1 SLX4	1.65e-04	184	124	5	4e3ba64692868563a579902aa9c6f88cab5bce26
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3F RASGRF2 RASIP1 TNS1 SH3RF3	1.69e-04	185	124	5	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	RASGRF2 ESR2 FBXL7 RAPGEF3 NEURL1B	1.69e-04	185	124	5	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK3 GLIS3 SNED1 TNS1 SH3RF3	1.69e-04	185	124	5	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRERF1 TSEN54 KANSL1 SWI5 MVB12B	1.77e-04	187	124	5	8c69fd469df2915c56ede534cee3ef23d5f64ebf
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP34 RICTOR HUWE1 KANSL1 SPEN	1.82e-04	188	124	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F RASGRF2 RASIP1 RAPGEF3 TNS1	1.82e-04	188	124	5	05de6677f9bb4b00fed47f4b72f4a2cd507cb0f2
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma-osteoclast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	IQSEC2 F5 ZNF462 ADAMTS14 GNS	1.82e-04	188	124	5	762b52f21d2bc5409f86746a904c4358490be9c0
ToppCell	droplet-Fat-SCAT-30m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRF2 APLP2 RASIP1 RAPGEF3 TNS1	1.82e-04	188	124	5	5cf060bb8adaefa9964187195d67993c1248ef47
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	USP34 L1CAM HCN3 CAMSAP3 CYP4X1	1.82e-04	188	124	5	b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCell	droplet-Fat-SCAT-30m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRF2 APLP2 RASIP1 RAPGEF3 TNS1	1.82e-04	188	124	5	449f9602df3c83b2110eb479a00d428d1b55b423
ToppCell	COVID-19-kidney-VWF+PLVAP+VCAM1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3F RASIP1 FBXL7 NEURL1B SH3RF3	1.86e-04	189	124	5	c121817ddad164e9cfe382c43d0cbc9215508d02
ToppCell	RA-14._Fibroblast_III\|RA / Chamber and Cluster_Paper	MFHAS1 GLIS3 SNED1 FBXL7 MMP19	1.86e-04	189	124	5	46e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 PKDCC SNED1 NEURL1B SH3RF3	1.96e-04	191	124	5	a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 PKDCC SNED1 NEURL1B SH3RF3	1.96e-04	191	124	5	8f6d592edc32fdb901af30501d4360512334e8c2
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3F RASGRF2 RASIP1 FBXL7 SH3RF3	2.01e-04	192	124	5	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 RASIP1 FBXL7 NEURL1B SH3RF3	2.01e-04	192	124	5	1ee4783051ec94ea94600f040edcb385fc4289f1
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F RASGRF2 APLP2 RASIP1 RAPGEF3	2.01e-04	192	124	5	945153c41dde6e90d103206955e1707b54eb0665
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F RASGRF2 APLP2 RASIP1 RAPGEF3	2.01e-04	192	124	5	6ab50579c63f31ca2cd41063a99b129f11c07510
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 SNED1 RASIP1 NEURL1B SH3RF3	2.01e-04	192	124	5	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RASIP1 FBXL7 FES NEURL1B SH3RF3	2.05e-04	193	124	5	ad2df9b77999780860141be6ec366afc0172a331
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL16 PPFIA4 HCN1 L1CAM TMEM151B	2.05e-04	193	124	5	5fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 SNED1 RASIP1 NEURL1B SH3RF3	2.05e-04	193	124	5	52e918884877b6659cdca0496390e440f73694a9
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)\|356C / Donor, Lineage, Cell class and subclass (all cells)	SEMA3F RASIP1 FBXL7 RAPGEF3 NEURL1B	2.10e-04	194	124	5	2e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MFHAS1 L1CAM CBLC SLMAP DOT1L	2.10e-04	194	124	5	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MFHAS1 L1CAM CBLC SLMAP DOT1L	2.10e-04	194	124	5	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 PKDCC FBXL7 NEURL1B SH3RF3	2.10e-04	194	124	5	cf0244a29934e515446ac917d3c30672b460fb04
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	SEMA3F RASIP1 FBXL7 RAPGEF3 NEURL1B	2.10e-04	194	124	5	b6b5b0ab506b05a005ba8a05a3c7f4c725ba9200
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 ATP10D FBXL7 NEURL1B SH3RF3	2.10e-04	194	124	5	240d122dcb9dd1ab2867503ad85869853adcacae
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 ATP10D FBXL7 NEURL1B SH3RF3	2.10e-04	194	124	5	ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCell	Endothelial-endothelial_cell_of_vein\|World / Lineage, Cell type, age group and donor	RASIP1 FBXL7 RAPGEF3 NEURL1B SH3RF3	2.10e-04	194	124	5	3cbd9622a68e89add90e589867d88c83c5a33476
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 PKDCC FBXL7 NEURL1B SH3RF3	2.10e-04	194	124	5	ba7f971fb9a19423602da60770f23d9fead4a451
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 SNED1 RASIP1 FBXL7 SH3RF3	2.10e-04	194	124	5	e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCell	COVID-19-kidney-PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	SNED1 RASIP1 FBXL7 NEURL1B SH3RF3	2.15e-04	195	124	5	a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-Venous_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SEMA3F NHSL2 FBXL7 RAPGEF3 NEURL1B	2.15e-04	195	124	5	cc3d6f98d310e8840ff497d7258c5ccf54e6c624
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3F RASGRF2 RASIP1 FBXL7 SH3RF3	2.15e-04	195	124	5	818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 PKDCC SNED1 FBXL7 SH3RF3	2.21e-04	196	124	5	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 SNED1 RASIP1 FBXL7 SH3RF3	2.21e-04	196	124	5	8ad8efb631164b46f0c082572270188e5ead20bf
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3F RASGRF2 RASIP1 FBXL7 SH3RF3	2.21e-04	196	124	5	7cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	ZNF462 SNED1 RASIP1 FBXL7 SH3RF3	2.21e-04	196	124	5	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 SNED1 RASIP1 FBXL7 SH3RF3	2.21e-04	196	124	5	ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 PKDCC SNED1 FBXL7 SH3RF3	2.21e-04	196	124	5	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 SNED1 RASIP1 FBXL7 SH3RF3	2.21e-04	196	124	5	9606ea7e42f707e69ea891b3521037613b9675f5
Disease	esophagus squamous cell carcinoma (is_implicated_in)	RICTOR DCC KMT2D FES SPEN	1.01e-06	45	118	5	DOID:3748 (is_implicated_in)
Disease	Paroxysmal atrial fibrillation	USP34 CAND2 PPFIA4 ESR2 MEX3C ZNF462	4.01e-05	156	118	6	C0235480
Disease	familial atrial fibrillation	USP34 CAND2 PPFIA4 ESR2 MEX3C ZNF462	4.01e-05	156	118	6	C3468561
Disease	Persistent atrial fibrillation	USP34 CAND2 PPFIA4 ESR2 MEX3C ZNF462	4.01e-05	156	118	6	C2585653
Disease	Atrial Fibrillation	USP34 CAND2 PPFIA4 ESR2 MEX3C ZNF462	4.62e-05	160	118	6	C0004238
Disease	double outlet right ventricle (implicated_via_orthology)	CFC1 CFC1B	4.74e-05	3	118	2	DOID:6406 (implicated_via_orthology)
Disease	Intellectual Disability	APC2 RTTN TSEN54 DCC ZNF462 FCSK KANSL1 BRD4 ASCC3	8.08e-05	447	118	9	C3714756
Disease	dextro-looped transposition of the great arteries (implicated_via_orthology)	CFC1 CFC1B	9.46e-05	4	118	2	DOID:0060770 (implicated_via_orthology)
Disease	right atrial isomerism (implicated_via_orthology)	CFC1 CFC1B	9.46e-05	4	118	2	DOID:0060856 (implicated_via_orthology)
Disease	guanylyl cyclase-activating protein 1 measurement	PGLYRP2 F5	9.46e-05	4	118	2	EFO_0801663
Disease	17-beta-hydroxysteroid dehydrogenase 14 measurement	PLEKHA4 EHMT2	1.57e-04	5	118	2	EFO_0802231
Disease	taste liking measurement	DCAF1 SEMA3F MFHAS1 GLIS3 DCC RASIP1 KANSL1 MVB12B	1.73e-04	388	118	8	EFO_0010155
Disease	Calcium channel blocker use measurement	USP34 MFHAS1 GLIS3 MEX3C WT1-AS FES	2.22e-04	213	118	6	EFO_0009930
Disease	melanoma (is_marker_for)	ESR2 EHMT2 BRD4	3.12e-04	33	118	3	DOID:1909 (is_marker_for)
Disease	brain measurement, neuroimaging measurement	GLIS3 PKDCC DCC ZNF462 FBXL7 KANSL1 FES TNS1 SH3RF3	3.77e-04	550	118	9	EFO_0004346, EFO_0004464
Disease	unipolar depression, bipolar disorder	ESR2 EMILIN3 DCC TUBGCP6 ASCC3	4.19e-04	156	118	5	EFO_0003761, MONDO_0004985
Disease	vital capacity	USP34 CAND2 CDK12 GLIS3 PKDCC TSEN54 MCCC1 DCC KANSL1 BRD4 SLMAP NEURL1B DOT1L TNS1	4.28e-04	1236	118	14	EFO_0004312
Disease	chronic obstructive pulmonary disease	MFHAS1 GLIS3 TSEN54 KANSL1 EHMT2 EPC1 SLMAP DOT1L DMWD TNS1	4.53e-04	688	118	10	EFO_0000341
Disease	blood urea nitrogen measurement	CDK12 HCN1 PLEKHA6 KIAA1614 ZNF462 WT1-AS PIP5K1B ASCC3	4.80e-04	452	118	8	EFO_0004741
Disease	Alzheimer disease, educational attainment	DOCK3 HCN1 ESR2 DCC INTS14 KANSL1	4.88e-04	247	118	6	EFO_0011015, MONDO_0004975
Disease	idiopathic pulmonary fibrosis (is_implicated_in)	EHMT2 BRD4	5.60e-04	9	118	2	DOID:0050156 (is_implicated_in)
Disease	Childhood Medulloblastoma	ESR2 BRD4 IRS2	6.85e-04	43	118	3	C0278510
Disease	Melanotic medulloblastoma	ESR2 BRD4 IRS2	6.85e-04	43	118	3	C1275668
Disease	Medullomyoblastoma	ESR2 BRD4 IRS2	6.85e-04	43	118	3	C0205833
Disease	Desmoplastic Medulloblastoma	ESR2 BRD4 IRS2	6.85e-04	43	118	3	C0751291
Disease	Adult Medulloblastoma	ESR2 BRD4 IRS2	6.85e-04	43	118	3	C0278876
Disease	atrial fibrillation	USP34 CAND2 PPFIA4 ESR2 MEX3C ZNF462 SPEN	7.50e-04	371	118	7	EFO_0000275
Disease	Prostatic Neoplasms	IL16 CDK12 ESR2 KMT2D PIK3R2 BRD4 BRPF1 STARD3 SPEN	8.46e-04	616	118	9	C0033578
Disease	Malignant neoplasm of prostate	IL16 CDK12 ESR2 KMT2D PIK3R2 BRD4 BRPF1 STARD3 SPEN	8.46e-04	616	118	9	C0376358
Disease	visceral heterotaxy (is_implicated_in)	CFC1 CFC1B	1.02e-03	12	118	2	DOID:0050545 (is_implicated_in)
Disease	Medulloblastoma	ESR2 BRD4 IRS2	1.07e-03	50	118	3	C0025149
Disease	brain connectivity measurement	SEMA3F MFHAS1 PKDCC KIAA1614 KANSL1 FES SH3RF3	1.16e-03	400	118	7	EFO_0005210
Disease	forced expiratory volume	MFHAS1 CDK12 GLIS3 PKDCC TSEN54 DCC WT1-AS KANSL1 SLMAP TNS1	1.28e-03	789	118	10	EFO_0004314
Disease	P wave duration	CAND2 HCN1	1.61e-03	15	118	2	EFO_0005094
Disease	YKL40 measurement	PPFIA4 PKDCC	1.61e-03	15	118	2	EFO_0004869
Disease	Profound Mental Retardation	TSEN54 DCC KANSL1 ASCC3	2.39e-03	139	118	4	C0020796
Disease	Mental Retardation, Psychosocial	TSEN54 DCC KANSL1 ASCC3	2.39e-03	139	118	4	C0025363
Disease	Mental deficiency	TSEN54 DCC KANSL1 ASCC3	2.39e-03	139	118	4	C0917816
Disease	aggressive behaviour measurement, ADHD symptom measurement	MFHAS1 HCN1 DCC	2.59e-03	68	118	3	EFO_0007826, EFO_0007860
Disease	prion disease	MFHAS1 ADAMTS14	2.59e-03	19	118	2	EFO_0004720
Disease	Endometrial Carcinoma	SEMA3F ESR2 PIK3R2	3.04e-03	72	118	3	C0476089
Disease	esophagus squamous cell carcinoma (is_marker_for)	RICTOR KMT2D EHMT2	3.29e-03	74	118	3	DOID:3748 (is_marker_for)
Disease	anxiety disorder (implicated_via_orthology)	HCN1 ESR2	3.48e-03	22	118	2	DOID:2030 (implicated_via_orthology)
Disease	osteoporosis (biomarker_via_orthology)	ESR2 IRS2	3.48e-03	22	118	2	DOID:11476 (biomarker_via_orthology)
Disease	Primary microcephaly	RTTN TUBGCP6	3.48e-03	22	118	2	C0431350
Disease	feeling "fed-up" measurement	HCN1 DCC KANSL1	3.54e-03	76	118	3	EFO_0009588
Disease	Self-injurious behavior	DCC FBXL7 FBXO27	3.81e-03	78	118	3	HP_0100716

Protein segments in the cluster

Peptide	Gene	Start	Entry
PINARHIPRTLSAVP	EPC1	771	Q9H2F5
HRPPLLFDLSRDPSE	ARSD	511	P51689
RTRHLLTDLPLPPEL	CDK12	661	Q9NYV4
RLSVSPPSLRDLLPR	CBLC	36	Q9ULV8
HSPIIRSEPFSPSLR	BRD4	1116	O60885
DPSTDPPLLTRARHQ	GTPBP3	421	Q969Y2
QSRLARLDPHPELLP	EHMT2	1186	Q96KQ7
ESRQPEGPSLRHLLP	AP5Z1	141	O43299
PAHPRSLVPSVLQRE	CFC1B	196	P0CG36
RSSTPQHPLLLAQPR	DOT1L	981	Q8TEK3
RPRPASSISLPIGHL	DMRTC1;	171	Q5HYR2
LAPLTRVLTPPHDVD	CAMSAP3	791	Q9P1Y5
LPRSLSRSNSLPHPA	DMWD	486	Q09019
PAHPRSLVPSVLQRE	CFC1	196	P0CG37
PSPILRAKHFDRLTP	ATP10D	1326	Q9P241
DTPPTLPRHSSHLRV	ADAMTS14	71	Q8WXS8
HLRSSSLLIPPLETA	CRYM	16	Q14894
SHPPLILPLGSSRLR	RASIP1	906	Q5U651
SAASALHLLSPRPRP	EDC4	771	Q6P2E9
RLLSIHIPALLPPTS	ANAPC1	1226	Q9H1A4
LAALQSDPPRPHRIL	APLP2	476	Q06481
PVHTTSKRPRLDPVL	FAM90A23	151	A8MXZ1
RPEPPKTRVSSLHLE	FAM47C	451	Q5HY64
RLHPEPPKTRVSSLH	FAM47C	701	Q5HY64
RPEPLETRVSHLRPE	FAM47C	751	Q5HY64
PLRVHITSLLPTPED	PAEP	56	P09466
RHLPSPPTLDSIITE	DCAF1	996	Q9Y4B6
VRPTHPLRSFANPLL	DCC	1336	P43146
LAEIPSHLPPQTRTL	LRTM1	41	Q9HBL6
TLLEAEPPHVLISRP	ESR2	271	Q92731
LSPVLPVSCRDPRHL	MFHAS1	621	Q9Y4C4
PRTSLPTPLRAHDIL	NUDT18	146	Q6ZVK8
PPIRHQVSTPILALS	GPR179	931	Q6PRD1
SPRRSSLNLPSRLPH	MYO15A	856	Q9UKN7
PPSSPRTLRLEKLGH	PPFIA4	701	O75335
LHELRRFLPPSLAPA	MESP2	101	Q0VG99
LRAAHLPLLTIEPPS	IQSEC2	586	Q5JU85
TSLLSPPHRRPTLHR	KIAA2026	346	Q5HYC2
LSSPLRLLPAEPRLH	KIAA1614	576	Q5VZ46
PVHTTSKRPRLDPVL	FAM90A22	151	A8MWA6
PVHTTSKRPRLDPVL	FAM90A14	151	P0C7W9
LPSTLPPHTARAALR	MMP19	116	Q99542
LSRTPEPRPSLSHLL	PGLYRP2	286	Q96PD5
SRHRPDLVPSTPSLF	PIP5K1B	456	O14986
PAHLPFLSPEVLRLL	FAM205A	281	Q6ZU69
PAHLPFLSPEVLRLL	FAM205BP	11	Q63HN1
THSPSLPLAREPVVL	IL16	541	Q14005
ETLAAPASLRPHRPR	KCNIP2	56	Q9NS61
PLTPVARDTPRHLAS	KANSL1	1001	Q7Z3B3
SPPSSPRALRLDRLH	PPFIA1	741	Q13136
SPGPVPRLVLSDLHL	L1CAM	611	P32004
ETLLPSHPPRRAALE	TUBGCP6	1001	Q96RT7
LLAIALHPALSVPPR	FOXRED2	16	Q8IWF2
LPAPPARTLHASLSR	HCN3	671	Q9P1Z3
ILSSLEPLHRPIESP	HUWE1	851	Q7Z6Z7
SLVPPGSSHTLPRRA	RICTOR	1286	Q6R327
APNLPRHISLTLPAT	MVB12B	216	Q9H7P6
HPARARPGLSLPATL	GID4	46	Q8IVV7
PLTHRLLCSEEPPRL	GPR149	211	Q86SP6
SLHRALASGPPPLRL	PARD6A	76	Q9NPB6
TPAHSLEQLRRLPLP	OOEP	16	A6NGQ2
PPTLPLHRALTLRFL	PIK3R2	211	O00459
FSTLELRDIPLRPHP	PLEKHG6	621	Q3KR16
SPGPVRAPLSRSHTL	IRS2	391	Q9Y4H2
LPPQDRHLPLASLVS	PCDHB14	491	Q9Y5E9
LPPLRTRSKSDPVLH	FAM189A2	266	Q15884
PSARLFPVLHPSREL	FCSK	486	Q8N0W3
HILRSTLPATALPLR	APC2	2156	O95996
REVRPLSASQPSLPH	HCN1	781	O60741
ARTLRKSPLHPIPAS	DOCK3	1856	Q8IZD9
RPSPAPSVALHIGRL	DMRTC2	346	Q8IXT2
PPPTRLTHPLIRLAS	FBXL7	91	Q9UJT9
EDLPLSPRSPLTPRH	GAS2L3	11	Q86XJ1
HISPRRVPAPSSILQ	GLIS3	621	Q8NEA6
DISSPPVLSRHLVLP	INTS14	261	Q96SY0
KESLRLHPPAPFISR	CYP4F12	386	Q9HCS2
ILLHFRVTPDPTRPL	CYP4X1	471	Q8N118
PRHLPSCSPALLLLV	GNS	16	P15586
SRPAQPPRLLHTADT	GLMP	201	Q8WWB7
PLVHLSTPRADPSTR	MCCC1	401	Q96RQ3
PNPRLRPSFTHILDS	INSRR	1231	P14616
ELPKSRRVSSLHPEP	FAM47A	546	Q5JRC9
AHLQRLREAPPSPLT	EMILIN3	281	Q9NT22
PELLLVVLSHVPPRT	FBXO27	31	Q8NI29
DHLLDRLPGPRVPTS	CAND2	216	O75155
RRPLAVLHAPVPTTA	KIFC2	791	Q96AC6
PVHTTSKRPRLDPVL	FAM90A24P	151	P0C7X0
SPSSLDPPEHLFRIR	UPF2	906	Q9HAU5
SSLLPAHRSPAVLPL	TESMIN	126	Q9Y4I5
PPPVLLLQDDRHSTS	FES	396	P07332
STFLPLRPLSRHPLS	MRPS31	6	Q92665
LRPLSRHPLSSGSPE	MRPS31	11	Q92665
LRALLPSSPPAEHTQ	RTTN	1661	Q86VV8
VASRFIDSHTPPLRP	SLC29A3	286	Q9BZD2
HLPPVRTISPLDRLS	RNF157	406	Q96PX1
LLPHSAPPSLRPLLD	PKDCC	351	Q504Y2
PTQDHLPATPRVRLS	SEMA3F	21	Q13275
RHTLLRAPAPELLPA	TSEN54	311	Q7Z6J9
SDELLPPLTHRLPRV	TMEM151B	351	Q8IW70
PPLTHRLPRVNTVDS	TMEM151B	356	Q8IW70
APLSPRTFHPLRSEA	F5	1041	P12259
TLGHLPPPSSSVRVR	NHSL2	731	Q5HYW2
RPRLLTPSPTTDLHS	PLEKHA4	206	Q9H4M7
ELSPCRSPSTPRHLR	RASGRF2	846	O14827
PVHTSSKRPRLDPIL	FAM90A12P	151	A8MX19
PVHTTSKRPRLDPVL	FAM90A13P	151	P0C7W8
SIEHPLARRVRSDPP	MEX3C	551	Q5U5Q3
VRVSIPLSILEPPHR	MIIP	281	Q5JXC2
PAVPLSQLHPRGLRS	ST6GAL2	281	Q96JF0
LRQSREHLLSPPRSP	SHISA7	421	A6NL88
ISQPLLSPRRCPLHL	WT1-AS	46	Q06250
ALHELRRFLPPSVAP	MESP1	101	Q9BRJ9
PTPTLVRPLLKLVHS	SRCAP	1366	Q6ZRS2
PRGDRPELLTPSSLH	SOWAHB	281	A6NEL2
PVHTTSKRPRLDPVL	FAM90A15P	151	P0C7V4
SLSSHLLPPPEKRRA	STARD3	31	Q14849
PPARLPELRLLNDHS	SNED1	1221	Q8TER0
LVPPEHSELSERRSP	SLX4	571	Q8IY92
IHTPPGSARRLPALS	BRPF1	446	P55201
ANPASPPLSLLVLHR	AIMP2	126	Q13155
PLRQFSILPPHILTR	ASCC3	1126	Q8N3C0
HLRGRSPTPALDPLA	SWI5	56	Q1ZZU3
PHQTLPLDTPRDISL	PLEKHA6	736	Q9Y2H5
RSHNPVPLSPLRSRV	RAPGEF3	856	O95398
DLEHPEPSLPLSRTR	SPEN	1886	Q96T58
SIRPEALHSPRAPLQ	SPEN	3111	Q96T58
LPPEIVPATLHRSRP	RPS10P5	96	Q9NQ39
RLPATSLRPHSVVSP	SH3RF3	636	Q8TEJ3
PLLPPHHIERVESSL	SPATA31D1	246	Q6ZQQ2
RLRSDVIHAPLPSPV	SLMAP	136	Q14BN4
VHNVPLSVLIRPLPS	SRXN1	41	Q9BYN0
HLESLVASRPSPQPL	TNS1	671	Q9HBL0
HRTLPDPSPPARLLA	NEURL1B	6	A8MQ27
PRSLHTPSLRPSDVV	TGM5	491	O43548
PSTVLHAARPPIKLL	ZCCHC14	626	Q8WYQ9
TLPRPRIVSLLSSHS	ZNF462	2111	Q96JM2
SLHIPTRDLPLSPDT	USP34	2706	Q70CQ2
PARTLRVLSAPHLPP	XRCC3	311	O43542
LTRVSSTLPHRPLLS	TRERF1	441	Q96PN7
SDPRPDRTHTQIRLP	GARIN5B	256	Q8N5Q1
ASPLPEALHLSRPLE	KMT2D	476	O14686