Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	SP100 ZNF680 ZNF585A ZNF354A ZNF560 ZNF678 ZNF273 ZNF175 TRPS1 ZNF254 NKX3-2 ZFP28 ZNF621 ZNF215 E4F1 ZIM3 ZNF595 PRDM2 ZNF585B ZNF675 ZNF12 ZBTB49 ZIK1 ZNF530 ZSCAN21 ZNF43 ZNF92 ZNF66 ZNF724 ZNF624 ZNF431 ZNF721 ZNF350 ZNF723 ZNF91 ZNF876P ZNF614 ZNF730	3.43e-12	1412	151	38	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF678 ZNF273 ZNF175 TRPS1 ZNF254 NKX3-2 ZFP28 ZNF621 ZNF215 E4F1 ZIM3 ZNF595 PRDM2 ZNF585B ZNF675 ZNF12 ZBTB49 ZIK1 ZNF530 ZSCAN21 ZNF43 ZNF92 ZNF66 ZNF724 ZNF624 ZNF431 ZNF721 ZNF350 ZNF723 ZNF91 ZNF876P ZNF614 ZNF730	9.17e-12	1459	151	38	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF671 ZNF680 ZNF585A ZNF354A ZNF678 ZNF273 ZNF175 ZNF254 NKX3-2 ZFP28 ZNF621 ZNF215 E4F1 ZIM3 ZNF595 ZNF585B ZNF675 ZNF12 ZBTB49 ZIK1 ZNF530 ZSCAN21 ZNF43 ZNF92 ZNF66 ZNF724 ZNF624 ZNF431 ZNF721 ZNF350 ZNF723 ZNF91 ZNF876P ZNF730	4.05e-11	1244	151	34	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF671 ZNF680 ZNF585A ZNF354A ZNF678 ZNF273 ZNF175 ZNF254 NKX3-2 ZFP28 ZNF621 ZNF215 E4F1 ZIM3 ZNF595 ZNF585B ZNF675 ZNF12 ZBTB49 ZIK1 ZNF530 ZSCAN21 ZNF43 ZNF92 ZNF66 ZNF724 ZNF624 ZNF431 ZNF721 ZNF350 ZNF723 ZNF91 ZNF876P ZNF730	7.22e-11	1271	151	34	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZNF175 TRPS1 NKX3-2 E4F1 PRDM2 ZBTB49 ZNF43 ZNF721 ZNF350 ZNF91	1.66e-04	320	151	10	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	ZNF175 TRPS1 NKX3-2 E4F1 PRDM2 ZBTB49 ZNF43 ZNF721 ZNF350 ZNF91	1.93e-04	326	151	10	GO:0001217
Domain	zf-C2H2	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF678 ZNF273 ZNF175 TRPS1 ZNF254 ZFP28 ZNF621 ZNF215 E4F1 ZIM3 ZNF595 PRDM2 ZXDB ZNF585B ZNF675 ZNF12 ZBTB49 ZIK1 ZNF530 ZSCAN21 ZNF43 ZNF92 ZNF624 ZNF431 ZNF721 ZNF350 ZNF91 ZNF614 ZNF730	1.64e-18	693	142	34	PF00096
Domain	KRAB	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF273 ZNF175 ZNF254 ZFP28 ZNF621 ZNF215 ZIM3 ZNF595 ZNF585B ZNF675 ZNF12 ZIK1 ZNF530 ZNF43 ZNF92 ZNF624 ZNF431 ZNF350 ZNF91 ZNF614 ZNF730	2.36e-18	358	142	26	PS50805
Domain	KRAB	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF273 ZNF175 ZNF254 ZFP28 ZNF621 ZNF215 ZIM3 ZNF595 ZNF585B ZNF675 ZNF12 ZIK1 ZNF530 ZNF43 ZNF92 ZNF624 ZNF431 ZNF350 ZNF91 ZNF614 ZNF730	2.36e-18	358	142	26	PF01352
Domain	KRAB	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF273 ZNF175 ZNF254 ZFP28 ZNF621 ZNF215 ZIM3 ZNF595 ZNF585B ZNF675 ZNF12 ZIK1 ZNF530 ZNF43 ZNF92 ZNF624 ZNF431 ZNF350 ZNF91 ZNF614 ZNF730	4.98e-18	369	142	26	SM00349
Domain	KRAB	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF273 ZNF175 ZNF254 ZFP28 ZNF621 ZNF215 ZIM3 ZNF595 ZNF585B ZNF675 ZNF12 ZIK1 ZNF530 ZNF43 ZNF92 ZNF624 ZNF431 ZNF350 ZNF91 ZNF614 ZNF730	5.33e-18	370	142	26	IPR001909
Domain	ZnF_C2H2	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF678 ZNF273 ZNF175 TRPS1 ZNF254 ZFP28 ZNF621 ZNF215 E4F1 ZIM3 ZNF595 PRDM2 ZXDB ZNF585B ZNF675 ZNF12 ZMAT3 ZBTB49 ZIK1 ZNF530 ZSCAN21 ZNF43 ZNF92 ZNF624 ZNF431 ZNF721 ZNF350 ZNF91 ZNF614 ZNF730	2.33e-17	808	142	35	SM00355
Domain	ZINC_FINGER_C2H2_2	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF678 ZNF273 ZNF175 TRPS1 ZNF254 ZFP28 ZNF621 ZNF215 E4F1 ZIM3 ZNF595 PRDM2 ZXDB ZNF585B ZNF675 ZNF12 ZBTB49 ZIK1 ZNF530 ZSCAN21 ZNF43 ZNF92 ZNF624 ZNF431 ZNF721 ZNF350 ZNF91 ZNF614 ZNF730	4.96e-17	775	142	34	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF678 ZNF273 ZNF175 TRPS1 ZNF254 ZFP28 ZNF621 ZNF215 E4F1 ZIM3 ZNF595 PRDM2 ZXDB ZNF585B ZNF675 ZNF12 ZBTB49 ZIK1 ZNF530 ZSCAN21 ZNF43 ZNF92 ZNF624 ZNF431 ZNF721 ZNF350 ZNF91 ZNF614 ZNF730	5.36e-17	777	142	34	PS00028
Domain	Znf_C2H2	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF678 ZNF273 ZNF175 TRPS1 ZNF254 ZFP28 ZNF621 ZNF215 E4F1 ZIM3 ZNF595 PRDM2 ZXDB ZNF585B ZNF675 ZNF12 ZBTB49 ZIK1 ZNF530 ZSCAN21 ZNF43 ZNF92 ZNF624 ZNF431 ZNF721 ZNF350 ZNF91 ZNF614 ZNF730	1.56e-16	805	142	34	IPR007087
Domain	-	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF273 ZNF175 ZNF254 ZFP28 ZNF621 ZNF215 E4F1 ZIM3 PRDM2 ZXDB ZNF585B ZNF675 ZNF12 ZBTB49 ZIK1 ZNF530 ZSCAN21 ZNF43 ZNF92 ZNF624 ZNF431 ZNF721 ZNF350 ZNF91 ZNF614 ZNF730	5.05e-16	679	142	31	3.30.160.60
Domain	Znf_C2H2-like	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF273 ZNF175 TRPS1 ZNF254 ZFP28 ZNF621 ZNF215 E4F1 ZIM3 PRDM2 ZXDB ZNF585B ZNF675 ZNF12 ZMAT3 ZBTB49 ZIK1 ZNF530 ZSCAN21 ZNF43 ZNF92 ZNF624 ZNF431 ZNF721 ZNF350 ZNF91 ZNF614 ZNF730	8.12e-16	796	142	33	IPR015880
Domain	Znf_C2H2/integrase_DNA-bd	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF273 ZNF175 ZNF254 ZFP28 ZNF621 ZNF215 E4F1 ZIM3 PRDM2 ZXDB ZNF585B ZNF675 ZNF12 ZBTB49 ZIK1 ZNF530 ZSCAN21 ZNF43 ZNF92 ZNF624 ZNF431 ZNF721 ZNF350 ZNF91 ZNF614 ZNF730	9.23e-16	694	142	31	IPR013087
Domain	zf-C2H2_6	ZNF671 ZNF680 ZNF354A ZNF560 ZNF273 ZFP28 ZNF621 E4F1 ZIM3 PRDM2 ZNF675 ZNF12 ZBTB49 ZNF530 ZNF43 ZNF92 ZNF624 ZNF431 ZNF721 ZNF91 ZNF730	2.92e-14	314	142	21	PF13912
Domain	Protein_kinase_C_a/b/g	PRKCB PRKCG	1.71e-04	3	142	2	IPR014375
Domain	P-loop_NTPase	MYO7A ABCA13 MYH7B KIF16B ABCC11 RRAGB SLFN14 FANCM MFN1 DNAH12 MDN1 SLFN11 SEPTIN10 POLQ DDX39A NLRP4	7.31e-04	848	142	16	IPR027417
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF678 ZNF273 ZNF175 ZNF254 NKX3-2 ZFP28 NBN GPAM ZNF621 ZNF215 RRAGB GRIN2A THOC3 ZIM3 ZNF595 ZNF585B CNOT6 ZNF675 ZNF12 ZIK1 CNOT6L ZNF530 ZNF43 ZNF92 PIP4K2A ZNF724 ZNF624 PRKCB ZNF431 ZNF721 ZNF350 DDX39A RPA2 ZNF614 ZNF730 RPAP2	3.94e-14	1387	114	41	M734
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	ZNF585A ZNF354A ZNF254 ZFP28 NBN RRAGB ZNF595 ZNF585B CNOT6 ZNF12 ZIK1 CNOT6L ZNF43 PIP4K2A ZNF624 ZNF721 ZNF91 RPA2	4.22e-05	768	114	18	MM14851
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	ZNF585A ZNF354A ZNF254 ZFP28 NBN RRAGB THOC3 ZNF595 ZNF585B CNOT6 ZNF12 ZIK1 CNOT6L ZNF43 PIP4K2A ZNF624 ZNF721 ZNF91 DDX39A RPA2 RPAP2	6.22e-05	1022	114	21	MM15436
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF680 ZNF354A ZNF678 ZNF273 ZNF595 ZNF92 ZNF724 ZNF624 ZNF721 ZNF91 ZNF614	5.12e-10	181	152	11	37372979
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF585A ZNF175 ZNF585B ZNF43 ZNF624 ZNF721 ZNF91	1.95e-09	49	152	7	9630514
Pubmed	Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.	ZNF254 ZNF595 ZNF43 ZNF721 ZNF91	4.33e-09	15	152	5	15885501
Pubmed	Specific and ubiquitous expression of different Zn finger protein genes in the mouse.	ZNF585A ZFP28 ZNF585B ZNF624	1.21e-08	7	152	4	3143103
Pubmed	Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.	ZNF254 ZNF595 ZNF43 ZNF721 ZNF91	1.63e-07	29	152	5	14563677
Pubmed	The human immunodeficiency virus coat protein gp120 promotes forward trafficking and surface clustering of NMDA receptors in membrane microdomains.	GRIN2A PRKCB PRKCG GRIN3A	1.98e-06	21	152	4	22114277
Pubmed	Sequence determinants on the NR2A and NR2B subunits of NMDA receptor responsible for specificity of phosphorylation by CaMKII.	GRIN2A PRKCB PRKCG	2.83e-06	7	152	3	12147342
Pubmed	The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.	ZNF43 ZNF92 ZNF91	4.51e-06	8	152	3	2023909
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDC42BPA COBLL1 RALGPS2 TBC1D22B FSD1 PTPN3 MDN1 CCDC138 PKP2 PRKCG PIBF1 BECN1 GOLGA4 DOP1A VCPIP1	6.15e-06	861	152	15	36931259
Pubmed	Genetics of dizziness: cerebellar and vestibular disorders.	CACNA1A MYO7A COCH	6.74e-06	9	152	3	24275721
Pubmed	Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1.	ZNF354A ZNF350 ZNF91	6.74e-06	9	152	3	23665872
Pubmed	Functional analysis of the SRY-KRAB interaction in mouse sex determination.	ZNF43 ZNF721 ZNF91	9.60e-06	10	152	3	18588511
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	WASHC2C COPZ1 SYNE1 TRPS1 CEP170P1 XDH HAUS3 CPS1 PDIA3 STN1 CNOT6 CNOT6L SGO2 PIBF1 DDX39A RPA2 TOR1AIP1	1.31e-05	1155	152	17	20360068
Pubmed	Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.	ZNF43 ZNF721 ZNF91	1.32e-05	11	152	3	15469996
Pubmed	Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease.	ZNF585A ZNF585B	1.90e-05	2	152	2	37668106
Pubmed	NLRP4 negatively regulates autophagic processes through an association with beclin1.	BECN1 NLRP4	1.90e-05	2	152	2	21209283
Pubmed	CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle development.	CNOT6 CNOT6L	1.90e-05	2	152	2	34788619
Pubmed	Recruitment of NBS1 into PML oncogenic domains via interaction with SP100 protein.	SP100 NBN	1.90e-05	2	152	2	12470659
Pubmed	The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence.	CNOT6 CNOT6L	1.90e-05	2	152	2	21233283
Pubmed	Identification of Protein Kinase C Isoforms Involved in Type 1 Diabetic Encephalopathy in Mice.	PRKCB PRKCG	1.90e-05	2	152	2	29744369
Pubmed	Calcium-dependent PKC isoforms have specialized roles in short-term synaptic plasticity.	PRKCB PRKCG	1.90e-05	2	152	2	24794094
Pubmed	The cytosolic splicing variant of NELL2 inhibits PKCβ1 in glial cells.	NELL2 PRKCB	1.90e-05	2	152	2	25450684
Pubmed	Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.	ZNF43 ZNF721 ZNF91	2.27e-05	13	152	3	19850934
Pubmed	The CNOT4 Subunit of the CCR4-NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis.	CNOT6 CNOT6L RPA2	2.88e-05	14	152	3	34026442
Pubmed	Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.	ZNF43 ZNF92 ZNF91	4.40e-05	16	152	3	8467795
Pubmed	Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals.	PRKCB PRKCG	5.68e-05	3	152	2	9814702
Pubmed	Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis.	CNOT6 CNOT6L	5.68e-05	3	152	2	30926667
Pubmed	Protein and molecular characterization of hippocampal protein kinase C in C57BL/6 and DBA/2 mice.	PRKCB PRKCG	5.68e-05	3	152	2	7760054
Pubmed	Tyrosine phosphorylation on spleen tyrosine kinase (Syk) is differentially regulated in human and murine platelets by protein kinase C isoforms.	PRKCB PRKCG	5.68e-05	3	152	2	23960082
Pubmed	NR3A-containing NMDARs promote neurotransmitter release and spike timing-dependent plasticity.	GRIN2A GRIN3A	5.68e-05	3	152	2	21297630
Pubmed	CNOT6L couples the selective degradation of maternal transcripts to meiotic cell cycle progression in mouse oocyte.	CNOT6 CNOT6L	5.68e-05	3	152	2	30478191
Pubmed	Desmosomal adhesiveness is developmentally regulated in the mouse embryo and modulated during trophectoderm migration.	PRKCB PRKCG	5.68e-05	3	152	2	22819675
Pubmed	Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways.	PRKCB PRKCG	5.68e-05	3	152	2	3755548
Pubmed	Phorbol diester-induced alterations in the expression of protein kinase C isozymes and their mRNAs. Analysis in wild-type and phorbol diester-resistant HL-60 cell clones.	PRKCB PRKCG	5.68e-05	3	152	2	1714454
Pubmed	Control of aversion by glycine-gated GluN1/GluN3A NMDA receptors in the adult medial habenula.	GRIN2A GRIN3A	5.68e-05	3	152	2	31601771
Pubmed	Altered Blood Gene Expression of Tumor-Related Genes (PRKCB, BECN1, and CDKN2A) in Alzheimer's Disease.	PRKCB BECN1	5.68e-05	3	152	2	26510741
Pubmed	Conventional protein kinase C plays a critical role in negative regulation of CD98-induced homotypic aggregation.	PRKCB PRKCG	5.68e-05	3	152	2	19895572
Pubmed	Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach.	PRKCB PRKCG	5.68e-05	3	152	2	19556521
Pubmed	Protein kinase C-betaII represses hepatocyte growth factor-induced invasion by preventing the association of adapter protein Gab1 and phosphatidylinositol 3-kinase in melanoma cells.	HGF PRKCB	5.68e-05	3	152	2	17625596
Pubmed	FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies.	CASP8AP2 SP100	5.68e-05	3	152	2	17245429
Pubmed	Syndrome disintegration: Exome sequencing reveals that Fitzsimmons syndrome is a co-occurrence of multiple events.	TRPS1 SACS	5.68e-05	3	152	2	27133561
Pubmed	Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein.	CPB2 PZP	5.68e-05	3	152	2	8662763
Pubmed	Calcium-Dependent Protein Kinase C Is Not Required for Post-Tetanic Potentiation at the Hippocampal CA3 to CA1 Synapse.	PRKCB PRKCG	5.68e-05	3	152	2	27307229
Pubmed	Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.	ZNF254 ZNF595 ZNF624	8.83e-05	20	152	3	7479878
Pubmed	Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.	ZNF254 ZNF595 ZNF624	8.83e-05	20	152	3	2542606
Pubmed	The DNA sequence and analysis of human chromosome 13.	B3GLCT CPB2 AMER2 SACS TEX26 PIBF1	1.07e-04	170	152	6	15057823
Pubmed	Serine phosphorylation of syndecan-2 proteoglycan cytoplasmic domain.	PRKCB PRKCG	1.13e-04	4	152	2	9244383
Pubmed	Analysis of NR3A receptor subunits in human native NMDA receptors.	GRIN2A GRIN3A	1.13e-04	4	152	2	17997397
Pubmed	Protein kinase C phosphorylation of syntaxin 4 in thrombin-activated human platelets.	PRKCB PRKCG	1.13e-04	4	152	2	10856305
Pubmed	Regulation of spontaneous meiosis resumption in mouse oocytes by various conventional PKC isozymes depends on cellular compartmentalization.	PRKCB PRKCG	1.13e-04	4	152	2	15367584
Pubmed	Characterisation of the expression of NMDA receptors in human astrocytes.	GRIN2A GRIN3A	1.13e-04	4	152	2	21152063
Pubmed	Protein kinase C phosphorylation of threonine at position 888 in Ca2+o-sensing receptor (CaR) inhibits coupling to Ca2+ store release.	PRKCB PRKCG	1.13e-04	4	152	2	9694886
Pubmed	Enhanced ethanol inhibition of recombinant N-methyl-D-aspartate receptors by magnesium: role of NR3A subunits.	GRIN2A GRIN3A	1.13e-04	4	152	2	18445116
Pubmed	Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral.	RALGPS2 NCK1	1.13e-04	4	152	2	10747847
Pubmed	Characterization of a 7.5-kDa protein kinase C substrate (RC3 protein, neurogranin) from rat brain.	PRKCB PRKCG	1.13e-04	4	152	2	8080473
Pubmed	NR2 to NR3B subunit switchover of NMDA receptors in early postnatal motoneurons.	GRIN2A GRIN3A	1.13e-04	4	152	2	15813953
Pubmed	Physical interaction between replication protein A (RPA) and MRN: involvement of RPA2 phosphorylation and the N-terminus of RPA1.	NBN RPA2	1.13e-04	4	152	2	19586055
Pubmed	Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communication.	PRKCB PRKCG	1.13e-04	4	152	2	10871288
Pubmed	Association of NR3A with the N-methyl-D-aspartate receptor NR1 and NR2 subunits.	GRIN2A GRIN3A	1.13e-04	4	152	2	12391275
Pubmed	Next-Generation Sequencing Identifies Pathogenic Variants in HGF, POU3F4, TECTA, and MYO7A in Consanguineous Pakistani Deaf Families.	HGF MYO7A	1.13e-04	4	152	2	33976695
Pubmed	Physiological regulation of Munc18/nSec1 phosphorylation on serine-313.	PRKCB PRKCG	1.13e-04	4	152	2	12950453
Pubmed	Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3σ.	CNOT6 ZMAT3	1.13e-04	4	152	2	24469038
Pubmed	Phosphorylation of Munc-18/n-Sec1/rbSec1 by protein kinase C: its implication in regulating the interaction of Munc-18/n-Sec1/rbSec1 with syntaxin.	PRKCB PRKCG	1.13e-04	4	152	2	8631738
Pubmed	mGluR5-PLCbeta4-PKCbeta2/PKCgamma pathways in hippocampal CA1 pyramidal neurons in pilocarpine model of status epilepticus in mGluR5+/+ mice.	PRKCB PRKCG	1.13e-04	4	152	2	18774262
Pubmed	Cell cycle phase-specific phosphorylation of human topoisomerase II alpha. Evidence of a role for protein kinase C.	PRKCB PRKCG	1.13e-04	4	152	2	7499337
Pubmed	Presynaptic Short-Term Plasticity Persists in the Absence of PKC Phosphorylation of Munc18-1.	PRKCB PRKCG	1.13e-04	4	152	2	34290081
Pubmed	Phosphorylation of eIF-4E on serine 209 by protein kinase C is inhibited by the translational repressors, 4E-binding proteins.	PRKCB PRKCG	1.13e-04	4	152	2	8662663
Pubmed	Protein kinase C phosphorylates RGS2 and modulates its capacity for negative regulation of Galpha 11 signaling.	PRKCB PRKCG	1.13e-04	4	152	2	11063746
Pubmed	Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure.	CNOT6 CNOT6L	1.13e-04	4	152	2	35385705
Pubmed	Regulation of ARNO nucleotide exchange by a PH domain electrostatic switch.	PRKCB PRKCG	1.13e-04	4	152	2	10531036
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	CCPG1 MYH7B RBM19 SLFN11 POLQ TOR1AIP1 VCPIP1	1.22e-04	250	152	7	33536335
Pubmed	A new member of the third class in the protein kinase C family, PKC lambda, expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells.	PRKCB PRKCG	1.88e-04	5	152	2	7513693
Pubmed	Role of two conserved cytoplasmic threonine residues (T410 and T412) in CD5 signaling.	PRKCB PRKCG	1.88e-04	5	152	2	11123317
Pubmed	PKCα integrates spatiotemporally distinct Ca2+ and autocrine BDNF signaling to facilitate synaptic plasticity.	PRKCB PRKCG	1.88e-04	5	152	2	30013171
Pubmed	The role of DOC-2/DAB2 protein phosphorylation in the inhibition of AP-1 activity. An underlying mechanism of its tumor-suppressive function in prostate cancer.	PRKCB PRKCG	1.88e-04	5	152	2	10542228
Pubmed	Rapid State-Dependent Alteration in Kv3 Channel Availability Drives Flexible Synaptic Signaling Dependent on Somatic Subthreshold Depolarization.	PRKCB PRKCG	1.88e-04	5	152	2	28228266
Pubmed	Protein kinase C regulates the phosphorylation and cellular localization of occludin.	PRKCB PRKCG	1.88e-04	5	152	2	11502742
Pubmed	Phosphorylation of vitronectin on Ser362 by protein kinase C attenuates its cleavage by plasmin.	PRKCB PRKCG	1.88e-04	5	152	2	9030777
Pubmed	Genetics of vestibular disorders: pathophysiological insights.	MYO7A COCH	1.88e-04	5	152	2	27083884
Pubmed	The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis.	ZNF254 ZNF595	1.88e-04	5	152	2	24190968
Pubmed	Phosphorylation of serine 1106 in the catalytic domain of topoisomerase II alpha regulates enzymatic activity and drug sensitivity.	PRKCB PRKCG	1.88e-04	5	152	2	12569090
Pubmed	Regulation of the ErbB3 binding protein Ebp1 by protein kinase C.	PRKCB PRKCG	1.88e-04	5	152	2	11325528
Pubmed	Cell type-specific expression of the genes for the protein kinase C family: down regulation of mRNAs for PKC alpha and nPKC epsilon upon in vitro differentiation of a mouse neuroblastoma cell line neuro 2a.	PRKCB PRKCG	1.88e-04	5	152	2	2590242
Pubmed	Protein kinase C activity regulates the onset of anaphase I in mouse oocytes.	PRKCB PRKCG	1.88e-04	5	152	2	15229137
Pubmed	A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction.	ZNF254 ZNF595	1.88e-04	5	152	2	20042539
Pubmed	The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex.	CNOT6 CNOT6L	1.88e-04	5	152	2	22977175
Pubmed	PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control.	PRKCB PRKCG	1.88e-04	5	152	2	23824069
Pubmed	Cnot8 eliminates naïve regulation networks and is essential for naïve-to-formative pluripotency transition.	CNOT6 CNOT6L	1.88e-04	5	152	2	35390160
Pubmed	And-1 is required for homologous recombination repair by regulating DNA end resection.	NBN RPA2	1.88e-04	5	152	2	27940557
Pubmed	Phosphorylation of Munc18 by protein kinase C regulates the kinetics of exocytosis.	PRKCB PRKCG	1.88e-04	5	152	2	12519779
Pubmed	Cholecystokinin facilitates glutamate release by increasing the number of readily releasable vesicles and releasing probability.	PRKCB PRKCG	1.88e-04	5	152	2	20392936
Pubmed	SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.	ZNF671 MYH7B NKX3-2 NCK1 ZXDB ZNF585B ZBTB49 AMER2 ZNF530 ZNF66 PRKCG SEPTIN10 DDX39A	2.02e-04	915	152	13	32393512
Pubmed	Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.	SYNE1 XDH GRIN3A	2.22e-04	27	152	3	18649358
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CASP8AP2 WASHC2C NBN AASDH THOC3 ZNF92 PIP4K2A SLFN11 VCPIP1 RPAP2	2.78e-04	588	152	10	38580884
Pubmed	Specific protein kinase C isoforms are required for rod photoreceptor differentiation.	PRKCB PRKCG	2.81e-04	6	152	2	22171059
Pubmed	Recruitment of the endosomal WASH complex is mediated by the extended 'tail' of Fam21 binding to the retromer protein Vps35.	WASHC2C CCDC93	2.81e-04	6	152	2	22070227
Pubmed	Identification of a phosphorylation site for calcium/calmodulindependent protein kinase II in the NR2B subunit of the N-methyl-D-aspartate receptor.	PRKCB PRKCG	2.81e-04	6	152	2	8940188
Pubmed	Localization of protein kinase C isoforms in the optic pathway of mouse embryos and their role in axon routing at the optic chiasm.	PRKCB PRKCG	2.81e-04	6	152	2	24863469
Pubmed	The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons.	ZNF254 ZNF595	2.81e-04	6	152	2	30846446
Pubmed	Expression and activity of protein kinase C isoenzymes during normal and abnormal murine palate development.	PRKCB PRKCG	2.81e-04	6	152	2	10879655
Interaction	LTBP2 interactions	ZNF273 ZNF254 E4F1 STN1 ZNF12 ZSCAN21 ZNF92 ZNF724 ZNF624 ZNF431	6.56e-10	85	148	10	int:LTBP2
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF254 ZNF675 ZNF43 ZNF66 ZNF724 ZNF431 ZNF723 ZNF91 ZNF730	3.54e-10	122	153	9	chr19p12
Cytoband	19p12	ZNF254 ZNF675 ZNF66 ZNF724 ZNF431 ZNF723 ZNF91 ZNF730	7.78e-10	90	153	8	19p12
Cytoband	4p16.3	NKX3-2 HAUS3 ZNF595 ZBTB49 ZNF721 ZNF876P	4.37e-07	85	153	6	4p16.3
Cytoband	6q15	CASP8AP2 MDN1 DOP1A	1.52e-04	31	153	3	6q15
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF671 ZNF585A ZNF175 ZFP28 ZIM3 ZNF585B SPTBN4 ZIK1 ZNF530 PRKCG ZNF350 NLRP4 ZNF614	1.92e-04	1192	153	13	chr19q13
Cytoband	19q13.43	ZNF671 ZIK1 ZNF530 NLRP4	2.13e-04	87	153	4	19q13.43
Cytoband	Ensembl 112 genes in cytogenetic band chr4p16	HAUS3 ZNF595 ZBTB49 ZNF721 ZNF876P	9.26e-04	222	153	5	chr4p16
Cytoband	Ensembl 112 genes in cytogenetic band chr13q12	B3GLCT RNF17 AMER2 SACS TEX26	1.17e-03	234	153	5	chr13q12
Cytoband	2q24.3	COBLL1 XIRP2	1.28e-03	16	153	2	2q24.3
Cytoband	13q12.3	B3GLCT TEX26	2.44e-03	22	153	2	13q12.3
Cytoband	7q11.21	ZNF680 ZNF273 ZNF92	2.74e-03	83	153	3	7q11.21
Cytoband	3q21	NCK1 PARP9	2.90e-03	24	153	2	3q21
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF671 ZNF680 ZNF585A ZNF354A ZNF560 ZNF678 ZNF273 ZNF175 TRPS1 ZNF254 ZFP28 ZNF621 ZNF215 E4F1 ZIM3 ZNF595 ZXDB ZNF585B ZNF675 ZNF12 ZBTB49 ZIK1 ZNF530 ZSCAN21 ZNF43 ZNF92 ZNF624 ZNF431 ZNF721 ZNF350 ZNF91 ZNF614 ZNF730	5.40e-21	718	106	33	28
GeneFamily	Glutamate ionotropic receptor NMDA type subunits	GRIN2A GRIN3A	7.01e-04	7	106	2	1201
GeneFamily	Schlafen family	SLFN14 SLFN11	7.01e-04	7	106	2	1110
GeneFamily	C2 domain containing protein kinases	PRKCB PRKCG	1.49e-03	10	106	2	835
GeneFamily	CCR4-NOT transcription complex	CNOT6 CNOT6L	1.81e-03	11	106	2	1023
ToppCell	NS-critical-d_0-4-Lymphoid-B_cell\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ZNF680 ZNF354A ZNF678 ZNF675 ZIK1 SACS ZNF614	2.15e-06	171	153	7	bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF680 GPAM FSD1 NELL2 ZIK1 ZNF350 MCUB	2.42e-06	174	153	7	ccc79febfcf588d8294ffc712338be96de8a5033
ToppCell	COVID-19-kidney-PCT-S3-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TPPP2 GPX5 GPAM CPB2 CPS1 C8A PZP	2.61e-06	176	153	7	b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1A AMPH SYNE1 GRIN2A SPTBN4 DGKI PRKCB	5.66e-06	198	153	7	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1A AMPH SYNE1 GRIN2A SPTBN4 DGKI PRKCB	5.66e-06	198	153	7	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AMPH SYNE1 GRIN2A SPTBN4 NELL2 DGKI PRKCB	5.66e-06	198	153	7	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	mild-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SP100 SYNE1 CNOT6L PIP4K2A PARP9 PZP GOLGA4	6.05e-06	200	153	7	d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CACNA1A AMPH SYNE1 GRIN2A SPTBN4 DGKI PRKCB	6.05e-06	200	153	7	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8\|TCGA-Bladder / Sample_Type by Project: Shred V9	ZNF680 ZNF254 ZNF675 ZNF43 ZNF92 ZNF66	1.34e-05	150	153	6	1aa9320d97ff10994ea024751790524fe133aba9
ToppCell	3'_v3-Lung-Lymphocytic_B-Memory_B_cells\|Lung / Manually curated celltypes from each tissue	COBLL1 RALGPS2 PRDM2 COCH FAM186A PRKCB	2.81e-05	171	153	6	9ecef653f6916572bf5fbee5aea6c577d04e96ba
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF ABCA13 SYNE1 TEX15 SLFN14 PRAM1	2.90e-05	172	153	6	d354424c1f861b6607dfd63b9724f4c237b30275
ToppCell	3'-Adult-Appendix-Epithelial-mature_enterocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPAM ZNF215 CPS1 ZSCAN21 ZNF66 SGO2	3.30e-05	176	153	6	30adf8f1638c6244586f8101c2590bb964dfae00
ToppCell	3'-Adult-Appendix-Epithelial-mature_enterocytic-Colonocyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPAM ZNF215 CPS1 ZSCAN21 ZNF66 SGO2	3.30e-05	176	153	6	23fa02d4c39e0b8faa1658116d50b6233a952ccc
ToppCell	normal-na-Lymphocytic_B-B_mem-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	SP100 COBLL1 RALGPS2 PRDM2 COCH PRKCB	3.98e-05	182	153	6	ee36ea6cb9a5a08aeb83f2b7a249255f0b1a9870
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	B3GLCT XDH ZNF12 ZNF530 SGO2 SLFN11	4.10e-05	183	153	6	ba7753e9fe2a6a87c5264f299ac97da2ddbda178
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	CACNA1A CASP8AP2 MFAP3L SGO2 GOLGA4 RPAP2	4.23e-05	184	153	6	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	Control-immature_Neutrophil-\|Control / Disease condition and Cell class	CACNA1A ZNF273 RALGPS2 MFAP3L SGO2 POLQ	4.23e-05	184	153	6	c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCell	Control-immature_Neutrophil\|Control / Disease condition and Cell class	CACNA1A ZNF273 RALGPS2 MFAP3L SGO2 POLQ	4.23e-05	184	153	6	2fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THOC3 NELL2 CNOT6L PIP4K2A PRKCB PZP	4.49e-05	186	153	6	9d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SP100 THOC3 PCNX2 CNOT6L PIP4K2A PRKCB	4.91e-05	189	153	6	df30478b288084a1bd48f660409dcc784040897c
ToppCell	COVID-19-lung-CD8+_T_cells\|lung / Disease (COVID-19 only), tissue and cell type	PCNX2 NELL2 CNOT6L PIP4K2A PRKCB PZP	5.51e-05	193	153	6	780e23e2705fc5c1b70e37568b79731ced5038bd
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	VPS13C COBLL1 RALGPS2 PRDM2 COCH PRKCB	5.67e-05	194	153	6	ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	COBLL1 RALGPS2 ZNF215 PRDM2 COCH PRKCB	5.67e-05	194	153	6	9b134a6e51b8556a04c362967fa474f8a7f59920
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AMPH SYNE1 GRIN2A SPTBN4 DGKI PRKCB	6.01e-05	196	153	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1A AMPH SYNE1 GRIN2A SPTBN4 DGKI	6.35e-05	198	153	6	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	SP100 CDC42BPA VPS13C COBLL1 PARP9 GOLGA4	6.53e-05	199	153	6	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Intermediate\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	CACNA1A XIRP2 TEX26 PKP2 FUCA1 SLFN11	6.53e-05	199	153	6	cf592d93612023a13de21e0fb8c6b13714f9af71
ToppCell	Control-Control-Myeloid-immature_Neutrophil\|Control / Disease, condition lineage and cell class	CACNA1A ZNF273 MFAP3L RBM19 POLQ GOLGA4	6.71e-05	200	153	6	118321ac443feb42aee171baccfc4610f00a8822
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SP100 SYNE1 CNOT6L PIP4K2A PZP GOLGA4	6.71e-05	200	153	6	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THOC3 NELL2 CNOT6L PIP4K2A PRKCB PZP	6.71e-05	200	153	6	e0cec0a844b7c1f8edee4c005af27766754e470a
Disease	Colorectal Carcinoma	ZNF560 ABCA13 SYNE1 GRIN2A MFN1 AMER2 SACS ZNF43 PDILT ZNF624 PRKCB PZP CCDC93	4.91e-05	702	146	13	C0009402
Disease	peritonitis (biomarker_via_orthology)	XDH BECN1	5.02e-04	7	146	2	DOID:8283 (biomarker_via_orthology)
Disease	cerebellar ataxia (implicated_via_orthology)	CACNA1A VPS13C	6.68e-04	8	146	2	DOID:0050753 (implicated_via_orthology)
Disease	beta-Ala-His dipeptidase measurement	ZNF254 ZNF675	6.68e-04	8	146	2	EFO_0008033
Disease	obesity (biomarker_via_orthology)	XDH GPAM APOBEC1 CPS1 PRKCB	8.42e-04	147	146	5	DOID:9970 (biomarker_via_orthology)
Disease	cholesteryl ester measurement, high density lipoprotein cholesterol measurement	COBLL1 TRPS1 KIF16B GPAM CPS1 SBF2 MCUB	9.58e-04	312	146	7	EFO_0004612, EFO_0010351
Disease	total cholesterol measurement, high density lipoprotein cholesterol measurement	COBLL1 TRPS1 KIF16B GPAM CPS1 SBF2 MCUB	1.01e-03	315	146	7	EFO_0004574, EFO_0004612
Disease	diabetes mellitus (is_marker_for)	HGF CPB2 FUCA1	1.10e-03	41	146	3	DOID:9351 (is_marker_for)
Disease	status epilepticus (biomarker_via_orthology)	GRIN2A MFN1 PRKCB BECN1	1.56e-03	100	146	4	DOID:1824 (biomarker_via_orthology)
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	COBLL1 GPAM CPS1 MCUB	1.74e-03	103	146	4	EFO_0008595, EFO_0020944
Disease	chronic kidney disease (is_implicated_in)	XDH CPB2	2.13e-03	14	146	2	DOID:784 (is_implicated_in)
Disease	Left ventricular noncompaction	MYH7B PKP2	2.13e-03	14	146	2	C1960469
Disease	3-hydroxyanthranilic acid measurement	CCPG1 PCNX2	2.45e-03	15	146	2	EFO_0010447
Disease	free cholesterol to total lipids in very large HDL percentage	COBLL1 TRPS1 GPAM	2.58e-03	55	146	3	EFO_0022288
Disease	cochlin measurement	COPZ1 COCH	2.79e-03	16	146	2	EFO_0801481
Disease	filaggrin gene expression measurement	TRPS1 ZNF254	2.79e-03	16	146	2	EFO_0020899
Disease	gout, hyperuricemia	ZNF724 ZNF730	2.79e-03	16	146	2	EFO_0004274, EFO_0009104
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	COBLL1 GPAM CPS1 MCUB	3.12e-03	121	146	4	EFO_0008595, EFO_0020943
Disease	free cholesterol to total lipids in medium HDL percentage	COBLL1 TRPS1 GPAM	3.30e-03	60	146	3	EFO_0022282
Disease	free cholesterol in HDL measurement	COBLL1 TRPS1 GPAM	3.46e-03	61	146	3	EFO_0022264
Disease	choline measurement	PLB1 TRPS1 GPAM CPS1	4.04e-03	130	146	4	EFO_0010116
Disease	phospholipids:total lipids ratio, intermediate density lipoprotein measurement	GPAM CPS1 MCUB	4.51e-03	67	146	3	EFO_0008595, EFO_0020946
Disease	Joubert syndrome 1	PIBF1 CPLANE1	4.80e-03	21	146	2	C4551568
Disease	triglycerides to total lipids in very small VLDL percentage	COBLL1 GPAM PRAM1	4.90e-03	69	146	3	EFO_0022341
Disease	free cholesterol measurement, high density lipoprotein cholesterol measurement	COBLL1 TRPS1 GPAM CPS1 SBF2 MCUB	4.92e-03	315	146	6	EFO_0004612, EFO_0008591

Protein segments in the cluster

Peptide	Gene	Start	Entry
SIKSAKLENSTFFHK	CACNA1A	456	O00555
SVAKSHSFFSLLKKN	AMER2	156	Q8N7J2
SNSFHAKRAEQLKKS	B3GLCT	66	Q6Y288
KFIFTRIFTKVQTAH	C8A	286	P07357
KNTTNHVEVNFIKKF	APOBEC1	56	P41238
NRSFSLKNVKHFVLD	DDX39A	181	O00148
KKQVSHDFLETRFKI	FBXO34	551	Q9NWN3
KTHFISNTKDSVKFF	ABCA13	2541	Q86UQ4
KSRNIQFEAFHVFKV	CAB39	266	Q9Y376
RQRSHSSIQFSFKEK	DOP1A	1261	Q5JWR5
VEKKQINKFKSFHET	AASDH	111	Q4L235
FRNNHKTARTFDTVK	CASP8AP2	146	Q9UKL3
FSFFQRSKKKRDQTA	COBLL1	241	Q53SF7
FKNVSSLEAKFHKEI	AMPH	206	P49418
SRSHAIFTIKFTQAK	KIF16B	221	Q96L93
QKAQKHFNKSFIDTS	RBM19	56	Q9Y4C8
NIVSKLKFVKVDSHF	PZP	341	P20742
TLNDSSHKKFFDVSK	IREB2	16	P48200
KKFFIHQRQKQAESR	PTPN3	266	P26045
KSEFLATKAKQFQRS	PARP9	361	Q8IXQ6
SAVKTKFEQHTIRAK	MFN1	331	Q8IWA4
SKLSQEQKTKHRIFS	nan	1256	O00370
SSHLKKTEKAINEFF	MFAP3L	176	O75121
SQKHTRKNTQSFKRK	MDN1	5086	Q9NU22
SRQFLQFFHKKSKQQ	MCUB	281	Q9NWR8
KTFNKQVTHVIFKDG	MCPH1	41	Q8NEM0
TATAEQFFQKLRNKH	NELL2	71	Q99435
DFSVSLKAQGKNKHF	NCK1	316	P16333
VEFHEIRQVKASFKK	SBF2	1341	Q86WG5
KKKAQSRFTQHQNTV	GOLGA4	1446	Q13439
VSFTAKHANKVKVLD	FSD1	401	Q9BTV5
DIHRNKRKVFSKIFS	CYP26B1	136	Q9NR63
SDTFITHKKSSFIKN	FANCM	806	Q8IYD8
LDKLKKTNVFNATFH	BECN1	261	Q14457
KRKKAASFQTVSQLH	MYH7B	686	A7E2Y1
HRSFLSFKVIKVNKE	PCNX2	1766	A6NKB5
TSTFKNVTYKHREKQ	ITGB6	766	P18564
DKKNGFKTQHFVSAK	FUCA1	196	P04066
KVTRKASTALHNKLF	ABCC11	886	Q96J66
QKAFEKNIFNKTHRT	COPZ1	41	P61923
QLTKTVIKDHFKESF	DNAH12	2146	Q6ZR08
KTNHSKTSKLQTAFR	KBTBD2	331	Q8IY47
KRKKDHFRNDTNTQS	FBXO25	66	Q8TCJ0
VHEVKNHKFTARFFK	PRKCB	31	P05771
HEVKSHKFTARFFKQ	PRKCG	31	P05129
TKTYQAHAKQKFSRL	NLRP4	96	Q96MN2
RNTIHEFKKSAKTTL	HGF	36	P14210
FHLTQIKKVRKQDFQ	CHRDL2	376	Q6WN34
SFIEEKQQHFKTKRV	GRIN3A	986	Q8TCU5
KQLNIKLTSFKAVHF	GLYATL3	121	Q5SZD4
KKRSRAAFSHAQVFE	NKX3-2	206	P78367
RQISAVHKETKQFFT	CCDC93	506	Q567U6
AVQKSRKVDSKSLFH	CPS1	1476	P31327
NLKKFSDSVKSTFRH	CCPG1	521	Q9ULG6
HKKTIKNEANFFFQS	IGSF1	271	Q8N6C5
QHSVENKPKTAAFFK	CCDC138	471	Q96M89
LIVKKKQVHFFVNAS	CPB2	61	Q96IY4
KRHQSKTKSQNVFRA	CPLANE1	1601	Q9H799
QQKFSFHSKEIVAIS	DGKI	271	O75912
VNIQKQLETFHSTFK	POLQ	2486	O75417
VSAQEHSFFLSKRNK	HAUS3	491	Q68CZ6
FQFSKKIRQSIDKTA	CEP170P1	131	Q96L14
FSKDAKVRESHFLQK	KHNYN	486	O15037
AKDAFKILSKNSSHF	SLC44A3	511	Q8N4M1
KRYKTKNAQQVHFRT	E4F1	526	Q66K89
VSLTEHKKKQRTNFL	FAM186A	96	A6NE01
NGEKEQKVFSFLKHS	GPX5	141	O75715
KALKHTAQKFFTVDA	COCH	246	O43405
KRKQFHASVIDSVTK	SACS	2776	Q9NZJ4
FFKTEKFTLVQKHTV	CNOT6	286	Q9ULM6
KHFVAQKVKLFRASD	PIP4K2A	21	P48426
HFKVAFTQRKVELSK	KLHL30-AS1	6	Q8NEE0
FRSKQNVKFAASVKS	PRDM2	1551	Q13029
RKHFKSTSNKNVSVI	RALGPS2	506	Q86X27
KFGRSFLSKNATKHQ	PDILT	361	Q8N807
QVNFKKDTTSKAIHS	STN1	251	Q9H668
KLNFTESTHVEFKRF	SLFN14	201	P0C7P3
LKNKKASSFHEFARN	TBC1D22B	51	Q9NU19
KFVTLSNVLKHFDQT	SYNE1	881	Q8NF91
TFIFLNAKQHKKLSS	NBN	226	O60934
KLNFAVASRKTFSHE	PDIA3	296	P30101
LKVSQSKEHQQFITF	GPAM	706	Q9HCL2
SHQDFRSIKAKFQAS	PRAM1	11	Q96QH2
KQFSTKHFQEYVKRT	SLFN11	216	Q7Z7L1
SKASRQTFVIHKLEK	SGO2	531	Q562F6
VGQKTTRHKFENKIN	PLB1	676	Q6P1J6
KTHQFFVKSFTTPTK	CDC42BPA	1011	Q5VT25
SRNVFHIASQKNFKA	RBIS	11	Q8N0T1
ETAKFFTQVHQAIKT	TEX51	56	A0A1B0GUA7
KKRNHQNASRSFEKA	CCDC54	221	Q8NEL0
FFKTEKFTLVQKHTV	CNOT6L	286	Q96LI5
KVKAKNARTITFQQF	TPPP2	56	P59282
FKSQSLRSHFEKNTT	RNF17	651	Q9BXT8
KVSEKSHNTFKATNK	XIRP2	2051	A4UGR9
SHNTFKATNKKRETD	XIRP2	2056	A4UGR9
VQFSHSKDFQKVNRS	TRPS1	271	Q9UHF7
KAFNRSSNLTKHKII	ZNF431	491	Q8TF32
KKTFITVSALFSHNR	ZXDB	401	P98169
KSFKNTTIFNVHQRI	ZNF624	451	Q9P2J8
KVHNRDSIKNFQKSS	ZFP28	391	Q8NHY6
KAFRQSSALNEHKKI	ZNF876P	126	Q49A33
KSFRQNSTLIQHKKV	ZIM3	286	Q96PE6
LTQHKKTATRVNFYK	ZNF273	221	Q14593
VKVFSKFSNSNKHKI	ZNF595	151	Q8IYB9
KAFNRSSNLTKHKII	ZNF92	236	Q03936
KAFNQSSTLTKHKRI	ZNF92	376	Q03936
KFFSSKSNLIRHQEV	ZNF671	376	Q8TAW3
KAFTQFSNLTQHKRI	ZNF678	216	Q5SXM1
VKDFHKFSNSNRHKT	ZNF724	151	A8MTY0
KTFCSKSNLSKHQRV	ZSCAN21	451	Q9Y5A6
RVKSHKEFLNKTTHQ	TRAPPC11	206	Q7Z392
KVRDFLKVKFTNSNT	TOR1AIP1	531	Q5JTV8
VKVAGHLRSFQNKKS	RPA2	126	P15927
HLRSFQNKKSLVAFK	RPA2	131	P15927
HFKRKFAKSNQVSRS	RPAP2	336	Q8IXW5
FKEEISKRFKSHTDQ	UBQLN1	61	Q9UMX0
VKVFHKFSSSNSQKI	ZNF723	151	P0DPD5
KVFSKFANSNKDKTR	ZNF721	76	Q8TF20
KSFSQKATLIKHQRV	ZIK1	386	Q3SY52
DIVFKHFKRNKVEIS	SP100	51	P23497
SKVTEFLHQSKLKSF	PIBF1	451	Q8WXW3
KTHRSKAEEQFKFEV	THOC3	171	Q96J01
GKSFTKKSQLQVHQR	ZNF585B	696	Q52M93
KKHVFKLQTQDGSEF	SPTBN4	2491	Q9H254
KRVVKKDHSVNSFKN	WASHC2C	901	Q9Y4E1
SQYHARKSEVDKFNK	XDH	976	P47989
KTIHDSTKQRLKVSF	VPS13C	1521	Q709C8
AHRFEKISNIIKQFK	RRAGB	286	Q5VZM2
EQHELSHFKRTQTKK	TAAR2	6	Q9P1P5
SHFKRTQTKKEKFNC	TAAR2	11	Q9P1P5
VVKKKSEQLHNVTAF	VCPIP1	1011	Q96JH7
SKKKATSEIFHSQSF	SEPTIN10	421	Q9P0V9
SLTNHFSFEKKKARV	GART	796	P22102
GKSFTKKSQLQVHQR	ZNF585A	696	Q6P3V2
VKVFHKFSNSNRHKI	ZNF730	151	Q6ZMV8
KAFNQFSNLTTHKKI	ZNF675	291	Q8TD23
KAFNQFSNLTTHKRI	ZNF43	461	P17038
KAFSTKQKLIVHQRT	ZNF350	381	Q9GZX5
KAFNRSSNLTIHKFI	ZNF91	721	Q05481
VSQHFDFKRKALKQT	ZNF621	121	Q6ZSS3
FSKTKHSKFNESGQL	TRAM1	111	Q15629
SKAFNRSSNLVKHQK	ZNF215	496	Q9UL58
KAFNRSSNLTTHKKI	ZNF66	236	Q6ZN08
FRQHLESKQHKSKVS	ZMAT3	261	Q9HA38
RGFSNFSNLKEHKKT	ZBTB49	486	Q6ZSB9
SRKSFREKSVFIQHQ	ZNF530	216	Q6P9A1
KSFCKKSKFIIHQRT	ZNF12	276	P17014
FVDRSKAQKIKKSSH	TEX26	151	Q8N6G2
KTFINTSSLRKHEKN	ZNF354A	221	O60765
QGRIKTFSQSEKHIK	TEX15	961	Q9BXT5
KTRFSENAKCIHTKF	ZNF614	176	Q8N883
IHTKFQVFKHQRTQK	ZNF614	186	Q8N883
QFKKTDFVNSRTAKA	PKP2	861	Q99959
FNQFSNLTKHKKIHT	ZNF680	331	Q8NEM1
KSFNRSSTFTKHKVI	ZNF254	581	O75437
KAFTSKSQFKEHQRI	ZNF175	566	Q9Y473
FNKHQTTHTRDKSYK	ZNF175	686	Q9Y473
NKTSTIRKVSVFSKH	ZNF560	256	Q96MR9
VHSSRNKFIKQIFQA	MYO7A	581	Q13402
NSKNHKTKDNFKRSV	GRIN2A	1076	Q12879