Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessneuromast hair cell differentiation

SLC44A4 TMEM132E

3.08e-0521152GO:0048886
GeneOntologyBiologicalProcessneuromast development

SLC44A4 TMEM132E

3.08e-0521152GO:0048884
GeneOntologyBiologicalProcesslateral line development

SLC44A4 TMEM132E

3.08e-0521152GO:0048882
GeneOntologyBiologicalProcessneuromast hair cell development

SLC44A4 TMEM132E

3.08e-0521152GO:0035675
GeneOntologyBiologicalProcesslateral line system development

SLC44A4 TMEM132E

9.21e-0531152GO:0048925
DomainCUB

ATRN CSMD2 CSMD3 MEGF8 PCOLCE

1.14e-05491135PF00431
DomainCUB

ATRN CSMD2 CSMD3 MEGF8 PCOLCE

1.26e-05501135SM00042
Domain-

ATRN CSMD2 CSMD3 MEGF8 PCOLCE

1.54e-055211352.60.120.290
DomainCUB

ATRN CSMD2 CSMD3 MEGF8 PCOLCE

1.69e-05531135PS01180
DomainCUB_dom

ATRN CSMD2 CSMD3 MEGF8 PCOLCE

2.42e-05571135IPR000859
DomainKringle-like

F12 CCN5 LPA LY75

4.01e-05321134IPR013806
DomainSushi

CSMD2 CR2 CSMD3 SUSD2

2.75e-04521134PF00084
DomainCCP

CSMD2 CR2 CSMD3 SUSD2

3.18e-04541134SM00032
DomainHEMATOPO_REC_L_F3

IL11RA EBI3

3.59e-0451132PS01354
DomainHematopoietin_rcpt_L_F3_CS

IL11RA EBI3

3.59e-0451132IPR003530
DomainSUSHI

CSMD2 CR2 CSMD3 SUSD2

3.66e-04561134PS50923
DomainGrowth_fac_rcpt_

ATRN STAB1 CCN5 FBN2 MEGF8 TIE1

3.73e-041561136IPR009030
DomainSushi_SCR_CCP_dom

CSMD2 CR2 CSMD3 SUSD2

3.92e-04571134IPR000436
DomainEGF_3

ATRN F12 STAB1 FBN2 MEGF8 TIE1 ADAM2

5.69e-042351137PS50026
DomainEGF_LAM_2

ATRN STAB1 MEGF8

7.77e-04301133PS50027
DomainEGF_LAM_1

ATRN STAB1 MEGF8

7.77e-04301133PS01248
DomainEGF_1

ATRN F12 STAB1 FBN2 MEGF8 TIE1 ADAM2

9.21e-042551137PS00022
DomainEGF_2

ATRN F12 STAB1 FBN2 MEGF8 TIE1 ADAM2

1.15e-032651137PS01186
DomainEGF_Lam

ATRN STAB1 MEGF8

1.23e-03351133SM00180
DomainLaminin_EGF

ATRN STAB1 MEGF8

1.23e-03351133PF00053
DomainLaminin_EGF

ATRN STAB1 MEGF8

1.56e-03381133IPR002049
DomainEGF_dom

STAB1 MEGF8

2.30e-03121132IPR024731
DomainEGF_3

STAB1 MEGF8

2.30e-03121132PF12947
Domainfn3

IL11RA IL12RB2 OBSCN TIE1 EBI3

3.05e-031621135PF00041
DomainEGF

ATRN F12 STAB1 FBN2 MEGF8 TIE1

3.07e-032351136SM00181
DomainFN_type2_col-bd

F12 LY75

3.15e-03141132IPR000562
DomainFN2_2

F12 LY75

3.15e-03141132PS51092
DomainFN2_1

F12 LY75

3.15e-03141132PS00023
Domainfn2

F12 LY75

3.15e-03141132PF00040
DomainFN2

F12 LY75

3.15e-03141132SM00059
DomainTRYPSIN_HIS

PRSS56 F12 TPSD1 LPA

3.55e-031031134IPR018114
DomainTRYPSIN_SER

PRSS56 F12 TPSD1 LPA

3.93e-031061134PS00135
DomainTRYPSIN_HIS

PRSS56 F12 TPSD1 LPA

4.06e-031071134PS00134
DomainEGF-like_dom

ATRN F12 STAB1 FBN2 MEGF8 TIE1

4.08e-032491136IPR000742
DomainKringle_CS

F12 LPA

4.65e-03171132IPR018056
DomainA/G_cyclase_CS

ADCY6 GUCY2D

4.65e-03171132IPR018297
DomainKRINGLE_1

F12 LPA

4.65e-03171132PS00021
DomainKR

F12 LPA

4.65e-03171132SM00130
DomainKringle

F12 LPA

4.65e-03171132IPR000001
DomainKRINGLE_2

F12 LPA

4.65e-03171132PS50070
DomainKringle

F12 LPA

4.65e-03171132PF00051
DomainPeptidase_S1A

PRSS56 F12 TPSD1 LPA

4.93e-031131134IPR001314
DomainEGF-like_CS

ATRN F12 STAB1 FBN2 MEGF8 TIE1

5.12e-032611136IPR013032
DomainTerpenoid_cyclase/PrenylTrfase

ASIC3 A2ML1

5.21e-03181132IPR008930
Domain-

ADCY6 GUCY2D

5.21e-031811323.30.70.1230
DomainNucleotide_cyclase

ADCY6 GUCY2D

5.21e-03181132IPR029787
DomainTRYPSIN_DOM

PRSS56 F12 TPSD1 LPA

5.25e-031151134PS50240
DomainFN3

IL11RA IL12RB2 OBSCN TIE1 EBI3

5.36e-031851135SM00060
DomainTryp_SPc

PRSS56 F12 TPSD1 LPA

5.58e-031171134SM00020
DomainEGF_extracell

ATRN STAB1 TIE1

5.74e-03601133IPR013111
DomainEGF_2

ATRN STAB1 TIE1

5.74e-03601133PF07974
DomainGuanylate_cyc

ADCY6 GUCY2D

5.80e-03191132PF00211
DomainGUANYLATE_CYCLASE_2

ADCY6 GUCY2D

5.80e-03191132PS50125
DomainA/G_cyclase

ADCY6 GUCY2D

5.80e-03191132IPR001054
DomainGUANYLATE_CYCLASE_1

ADCY6 GUCY2D

5.80e-03191132PS00452
DomainCYCc

ADCY6 GUCY2D

5.80e-03191132SM00044
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

IL12RB2 DCDC1 SH3BP2 BACH2 FBF1 PRSS56 NCKAP5L ADCY6 PASK SCAF1 ZNF469 FBN2 DPF3 XRN1 AGBL1 UNC80 TP53

2.10e-0711161171731753913
Pubmed

Plk4 is required for cytokinesis and maintenance of chromosomal stability.

RTKN PRKDC TP53

7.37e-076117320348415
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ATRN OBSCN BRME1 CSMD2 ATXN1L ESRP2 SCAF1 PARP4 PRKDC EIF3D TMEM200C FBXO34

7.46e-067361171229676528
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

CCDC174 SH3BP2 TAB2 RTKN NCKAP5L RASSF7 RUSC2 SHKBP1 PASK XRN1 PABPC1L EIF3D MAPK7 RNF138

1.08e-0510381171426673895
Pubmed

Modeling amplified p53 responses under DNA-PK inhibition in DNA damage response.

PRKDC TP53

1.12e-052117228177883
Pubmed

Mutations in the p53 and scid genes do not cooperate in lymphomagenesis in doubly heterozygous mice.

PRKDC TP53

1.12e-052117210082662
Pubmed

E3 ubiquitin-ligase RNF138 may regulate p53 protein expression to regulate the self-renewal and tumorigenicity of glioma stem cells.

RNF138 TP53

1.12e-052117238156932
Pubmed

Silibinin up-regulates DNA-protein kinase-dependent p53 activation to enhance UVB-induced apoptosis in mouse epithelial JB6 cells.

PRKDC TP53

1.12e-052117215792956
Pubmed

Evidence for nonautonomous effect of p53 tumor suppressor in carcinogenesis.

PRKDC TP53

1.12e-052117215753354
Pubmed

RBCK1 promotes p53 degradation via ubiquitination in renal cell carcinoma.

RBCK1 TP53

1.12e-052117230874541
Pubmed

DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53.

PRKDC TP53

1.12e-052117212065413
Pubmed

DNA-PKcs, a novel functional target of acriflavine, mediates acriflavine's p53-dependent synergistic anti-tumor efficiency with melphalan.

PRKDC TP53

1.12e-052117227693638
Pubmed

p53 induction, cell cycle checkpoints, and apoptosis in DNAPK-deficient scid mice.

PRKDC TP53

1.12e-05211729006086
Pubmed

Phosphorylation by DNAPK inhibits the DNA-binding function of p53/T antigen complex in vitro.

PRKDC TP53

1.12e-052117210470151
Pubmed

Radiosensitivity profiles from a panel of ovarian cancer cell lines exhibiting genetic alterations in p53 and disparate DNA-dependent protein kinase activities.

PRKDC TP53

1.12e-052117220204287
Pubmed

Serum lipid profile in psoriatic patients: correlation between vascular adhesion protein 1 and lipoprotein (a).

LPA AOC3

1.12e-052117222753196
Pubmed

TOE1 interacts with p53 to modulate its transactivation potential.

TOE1 TP53

1.12e-052117219508870
Pubmed

Cabin1 restrains p53 activity on chromatin.

CABIN1 TP53

1.12e-052117219668210
Pubmed

Glucocorticoid-induced TNF receptor-triggered T cells are key modulators for survival/death of neural stem/progenitor cells induced by ischemic stroke.

TNFRSF18 PRKDC

1.12e-052117222052192
Pubmed

BALB/c alleles for Prkdc and Cdkn2a interact to modify tumor susceptibility in Trp53+/- mice.

PRKDC TP53

1.12e-052117212750252
Pubmed

p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes.

PRKDC TP53

1.12e-05211728598286
Pubmed

IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells.

PRKDC TP53

1.12e-052117211970883
Pubmed

DNA double-strand breaks, p53, and apoptosis during lymphomagenesis in scid/scid mice.

PRKDC TP53

1.12e-05211729679979
Pubmed

Structured DNA promotes phosphorylation of p53 by DNA-dependent protein kinase at serine 9 and threonine 18.

PRKDC TP53

1.12e-052117215355354
Pubmed

p53 and DNA-dependent protein kinase catalytic subunit independently function in regulating actin damage-induced tetraploid G1 arrest.

PRKDC TP53

1.12e-052117222198295
Pubmed

Mutations in the p53 and SCID genes cooperate in tumorigenesis.

PRKDC TP53

1.12e-05211728769648
Pubmed

Establishment of murine basal cell carcinoma allografts: a potential model for preclinical drug testing and for molecular analysis.

PRKDC TP53

1.12e-052117221833014
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SETD1B KIF26A PPRC1 OBSCN SH2B2 RASSF7 BAHD1 ESRP2 SCAF1 MEGF8 KCNQ2 CACNA1H PRKDC CABIN1

2.16e-0511051171435748872
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FBF1 ZNF469 KRBA1 NEURL4 UNC80

3.20e-05107117511347906
Pubmed

Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells.

PRKDC TP53

3.36e-053117225362358
Pubmed

A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1.

FOXH1 TP53

3.36e-053117231068365
Pubmed

LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.

LACTB TP53

3.36e-053117229899406
Pubmed

p53 prevents maturation of T cell development to the immature CD4-CD8+ stage in Bcl11b-/- mice.

PRKDC TP53

3.36e-053117215694382
Pubmed

Interaction of p53 and DNA-PK in response to nucleoside analogues: potential role as a sensor complex for DNA damage.

PRKDC TP53

3.36e-053117211751391
Pubmed

The DNA damage response in DNA-dependent protein kinase-deficient SCID mouse cells: replication protein A hyperphosphorylation and p53 induction.

PRKDC TP53

3.36e-05311728943020
Pubmed

The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest.

PRKDC TP53

3.36e-053117210677503
Pubmed

The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice.

PRKDC TP53

3.36e-053117212559174
Pubmed

Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth.

PRKDC TP53

3.36e-053117229084207
Pubmed

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2.

PRKDC TP53

3.36e-05311729363941
Pubmed

Modification of two distinct COOH-terminal domains is required for murine p53 activation by bacterial Hsp70.

PRKDC TP53

3.36e-05311728940078
Pubmed

HIV: Integration triggers death.

PRKDC TP53

3.36e-053117223739334
Pubmed

HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration.

PRKDC TP53

3.36e-053117223739328
Pubmed

Human hepatic sinusoidal endothelial cells can be distinguished by expression of phenotypic markers related to their specialised functions in vivo.

STAB1 AOC3

3.36e-053117217006978
Pubmed

Asymmetry-defective oligodendrocyte progenitors are glioma precursors.

PRKDC TP53

3.36e-053117221907924
Pubmed

Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2.

MEF2B CABIN1

3.36e-053117212700764
Pubmed

Identification of two new members of the CSMD gene family.

CSMD2 CSMD3

3.36e-053117212906867
Pubmed

DNA repair-deficient Xpa/p53 knockout mice are sensitive to the non-genotoxic carcinogen cyclosporine A: escape of initiated cells from immunosurveillance?

PRKDC TP53

3.36e-053117219136475
Pubmed

Dysfunctional mammalian telomeres join with DNA double-strand breaks.

PRKDC TP53

3.36e-053117215010310
Pubmed

Gene network analysis of oxidative stress-mediated drug sensitivity in resistant ovarian carcinoma cells.

PRKDC TP53

3.36e-053117219918261
Pubmed

DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D.

PRKDC TP53

3.36e-05311729679063
Pubmed

Expression of Interactive Genes Associated with Apoptosis and Their Prognostic Value for Ovarian Serous Adenocarcinoma.

PRKDC TP53

3.36e-053117227629740
Pubmed

DNA-dependent protein kinase and checkpoint kinase 2 synergistically activate a latent population of p53 upon DNA damage.

PRKDC TP53

3.36e-053117214752107
Pubmed

NEURL4 regulates the transcriptional activity of tumor suppressor protein p53 by modulating its oligomerization.

NEURL4 TP53

3.36e-053117228977907
Pubmed

Granulosa cell tumorigenesis in genetically hypogonadal-immunodeficient mice grafted with ovaries from tumor-susceptible donors.

GHRHR PRKDC

3.36e-05311728339285
Pubmed

The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma.

PRKDC TP53

3.36e-053117221397859
Pubmed

A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathway.

RBCK1 TP53

3.36e-053117219277210
Pubmed

HIV integration and T cell death: additional commentary.

PRKDC TP53

3.36e-053117224321564
Pubmed

p53 deficiency does not affect mutation rate in the mouse germline.

PRKDC TP53

3.36e-053117215806156
Pubmed

Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination.

PRKDC TP53

3.36e-053117230072430
Pubmed

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

PRKDC TP53

3.36e-05311728769647
Pubmed

B cell acute lymphoblastic leukemia cells mediate RANK-RANKL-dependent bone destruction.

PRKDC TP53

3.36e-053117232938796
Pubmed

IL-12 p40 homodimer-dependent macrophage chemotaxis and respiratory viral inflammation are mediated through IL-12 receptor beta 1.

IL12RB2 TP53

3.36e-053117214662893
Pubmed

Synergy between Prkdc and Trp53 regulates stem cell proliferation and GI-ARS after irradiation.

PRKDC TP53

3.36e-053117228686579
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

JCAD TAB2 PLEKHG2 RTKN NCKAP5L SPECC1 RASSF7 RUSC2 SHKBP1 MEGF8 XRN1 TP53

3.49e-058611171236931259
Pubmed

Genetically distinct and clinically relevant classification of hepatocellular carcinoma: putative therapeutic targets.

FOXN3 TP53

6.70e-054117217983802
Pubmed

ELF3 suppresses gallbladder cancer development through downregulation of the EREG/EGFR/mTOR complex 1 signalling pathway.

PRKDC TP53

6.70e-054117237345534
Pubmed

Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2.

MEF2B CABIN1

6.70e-054117210531067
Pubmed

p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK.

PRKDC TP53

6.70e-054117218505846
Pubmed

Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells.

PRKDC TP53

6.70e-054117210435582
Pubmed

A novel role for acinus and MCM2 as host-specific signaling enhancers of DNA-damage-induced apoptosis in association with viral protein gp70.

PRKDC TP53

6.70e-054117219058849
Pubmed

MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma.

MEF2B CABIN1

6.70e-054117223974956
Pubmed

Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis.

SUSD2 CABIN1

6.70e-054117223624525
Pubmed

Synthetic Essentiality of Tryptophan 2,3-Dioxygenase 2 in APC-Mutated Colorectal Cancer.

PRKDC TP53

6.70e-054117235537038
Pubmed

Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy.

PRKDC TP53

6.70e-054117234388391
Pubmed

Adenovirus serotype 5 vaccine vectors trigger IL-27-dependent inhibitory CD4+ T cell responses that impair CD8+ T cell function.

IL12RB2 EBI3

6.70e-054117228239679
Pubmed

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.

PRKDC TP53

6.70e-054117219450527
Pubmed

BMK1 is involved in the regulation of p53 through disrupting the PML-MDM2 interaction.

MAPK7 TP53

6.70e-054117222869143
Pubmed

Binding sites of the Epstein-Barr virus and C3d receptor (CR2, CD21) for its three intracellular ligands, the p53 anti-oncoprotein, the p68 calcium binding protein and the nuclear p120 ribonucleoprotein.

CR2 TP53

6.70e-05411727753047
Pubmed

Low expression of Ku70/80, but high expression of DNA-PKcs, predict good response to radiotherapy in early breast cancer.

PRKDC TP53

6.70e-054117221042724
Pubmed

Contribution of IL-12/IL-35 common subunit p35 to maintaining the testicular immune privilege.

IL12RB2 EBI3

6.70e-054117224760014
Pubmed

OXTRHigh stroma fibroblasts control the invasion pattern of oral squamous cell carcinoma via ERK5 signaling.

PRKDC MAPK7

6.70e-054117236045118
Pubmed

DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse.

PRKDC TP53

6.70e-054117217145779
Pubmed

Regulation of the MDM2-p53 pathway by the ubiquitin ligase HERC2.

NEURL4 TP53

6.70e-054117231665549
Pubmed

MuLV-related endogenous retroviral elements and Flt3 participate in aberrant end-joining events that promote B-cell leukemogenesis.

PRKDC TP53

6.70e-054117224888589
Pubmed

p53-intact cancers escape tumor suppression through loss of long noncoding RNA Dino.

PRKDC TP53

6.70e-054117234192538
Pubmed

De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis.

MAPK7 TP53

6.70e-054117223381569
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ATRN JCAD PCYT1A BIN1 SYNM PPRC1 SPECC1 PAICS RBCK1 STAB1 KCNQ2 PRKDC EIF3D CABIN1

1.09e-0412851171435914814
Pubmed

Genetic interaction between DNA polymerase beta and DNA-PKcs in embryogenesis and neurogenesis.

PRKDC TP53

1.11e-045117215647757
Pubmed

Synthetic lethality of Chk1 inhibition combined with p53 and/or p21 loss during a DNA damage response in normal and tumor cells.

PRKDC TP53

1.11e-045117222430210
Pubmed

Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI.

PRKDC TP53

1.11e-045117233289702
Pubmed

DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice.

PRKDC TP53

1.11e-045117234521752
Pubmed

Regulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complex.

PRKDC TP53

1.11e-045117212756247
Pubmed

DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination.

PRKDC TP53

1.11e-045117218316419
Pubmed

IL-12 protects from psoriasiform skin inflammation.

IL12RB2 EBI3

1.11e-045117227892456
Pubmed

Polymorphisms of DNA repair genes and risk of glioma.

PRKDC TP53

1.11e-045117215313891
Pubmed

Excess of serotonin (5-HT) alters the segregation of ispilateral and contralateral retinal projections in monoamine oxidase A knock-out mice: possible role of 5-HT uptake in retinal ganglion cells during development.

HTR1B TP53

1.11e-045117210436056
Pubmed

CDKN1A regulates Langerhans cell survival and promotes Treg cell generation upon exposure to ionizing irradiation.

LY75 TP53

1.11e-045117226343536
Pubmed

p53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and Prkdc.

PRKDC TP53

1.11e-045117216687486
Pubmed

Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70.

PRKDC TP53

1.11e-045117228759779
Pubmed

DNA damage activates p53 through a phosphorylation-acetylation cascade.

PRKDC TP53

1.11e-04511729744860
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CSMD2 CR2 CSMD3 SUSD2

1.01e-04577741179
GeneFamilyGlucagon receptor family

GLP2R GHRHR

2.66e-046772269
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL11RA IL12RB2 IL17RC

7.57e-0442773602
GeneFamily5-hydroxytryptamine receptors, G protein-coupled

HTR1B HTR7

1.35e-0313772170
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SH3BP2 PLEKHG2 RTKN SH2B2 PLEKHG4B

1.86e-03206775682
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

TAB2 RBCK1

3.57e-032177289
GeneFamilyFibronectin type III domain containing

IL12RB2 OBSCN TIE1 EBI3

4.84e-03160774555
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

STAB1 LY75

5.87e-03277721253
ToppCellParenchymal-10x3prime_v2-Stromal-Mesofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IL11RA IL17RC CSMD2 CCN5 ZNF469 FBN2 GPR156 POLR1B

5.52e-0819811780cd930e374c2c48d1991b51c025f9801b22ecee7
ToppCellParenchymal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IL11RA IL17RC CSMD2 CCN5 ZNF469 FBN2 GPR156 POLR1B

5.52e-081981178e0df6d6ff2a9c41d813f84a2a5ee7cb5f6fc3e30
ToppCellCOVID-19_Severe-NK_CD56bright|World / disease group, cell group and cell class

IL12RB2 TMEM105 TNFRSF18 GLP2R TIE1 DPF3 KIR2DL4

1.98e-0715711779dcbabb377da7e93ec9f9abf09576a92877a7e02
ToppCellRA-04._Ventricular_Cardiomyocyte_I|RA / Chamber and Cluster_Paper

ASIC3 GHRHR SUSD2 LPA GREB1 STRC

4.67e-071101176af7095c6e1501a4440be39b5c16d4872dd6d66e5
ToppCellCOVID-19_Severe-NK_CD56bright|COVID-19_Severe / disease group, cell group and cell class

IL12RB2 TMEM105 TNFRSF18 GLP2R TIE1 KIR2DL4

4.01e-0615911769e2067f0d76769717f7048dab505fadd36bbb83e
ToppCellfacs-Heart-RV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEF2B TNFRSF18 TIGIT RELT LY75 NOBOX

6.30e-0617211762dcc9d67d6ecc35940eabbc8ed528f5f884f6976
ToppCellfacs-Heart-RV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEF2B TNFRSF18 TIGIT RELT LY75 NOBOX

6.30e-06172117664d2edbd8e2640b76225597883b1a524e6b1dd3b
ToppCellfacs-Heart-RV-18m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEF2B TNFRSF18 TIGIT RELT LY75 NOBOX

6.30e-061721176d061ea21bee179df5a525842e9a48621a8e1461b
ToppCellfacs-Heart-RA-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR7 PLEKHG2 SPECC1 ADCY6 FADS3 AOC3

8.97e-0618311760f02136359787bd78146617990968baa47a65d86
ToppCellfacs-Heart-RA-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR7 PLEKHG2 SPECC1 ADCY6 FADS3 AOC3

8.97e-0618311762f0dcc65ad4d90ef946919b4462280fdd20c5ea0
ToppCellfacs-Heart-LA-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR7 PLEKHG2 ADCY6 FADS3 SUSD2 AOC3

1.14e-0519111769c5d88f0d3c834c2419ec3da74652175153ba9df
ToppCellfacs-Heart-LA-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR7 PLEKHG2 ADCY6 FADS3 SUSD2 AOC3

1.14e-051911176a7494191a92984e5f53610bbbedd6714e9169e1c
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNM PLEKHG2 CCN5 FADS3 AOC3 CACNA1H

1.33e-051961176ac4c8571bd792538f8df7b9bdd90ef58405fd3b1
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNM PLEKHG2 CCN5 FADS3 AOC3 CACNA1H

1.33e-05196117670b2e0b4ff4f1bc03fb72ace07a8a44f4b415922
ToppCellRA-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

GHRHR CCN5 SUSD2 LPA STRC

1.33e-0511511750a37816898eaa18ae49d4d936e1a760f089e0ceb
ToppCellMild-Lymphoid-NK-NK|Mild / Condition, Lineage, Cell class and cell subclass

IL12RB2 BACH2 TNFRSF18 TIGIT TIE1 KIR2DL4

1.40e-0519811764999cc14642df704819be55594a07eab9c6527aa
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSMD3 GLP2R ADAM2 HEPHL1 UNC80

4.07e-05145117596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D3|356C / Donor, Lineage, Cell class and subclass (all cells)

BACH2 TNFRSF18 DPF3 KCNQ2 KIR2DL4

4.34e-051471175551c249f921ee0e70208abe207f2044d234d1ddc
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|368C / Donor, Lineage, Cell class and subclass (all cells)

ATRN TNFRSF18 BAHD1 TIGIT LY75

4.48e-05148117580470353e12599440f711b6e107730763376d04d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BAHD1 RUSC2 DPF3 AOC3 KCNQ2

4.48e-0514811756cd7ef4f29d9a0944f724d9d8117d4d25e517fe4
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PPRC1 SPECC1 STAB1 EBI3 PABPC1L

4.63e-051491175a85a051e0d82430160967e72fa04b55f43e84513
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PPRC1 SPECC1 STAB1 EBI3 PABPC1L

4.78e-0515011757a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCellsevere_influenza-NK_CD56bright|World / disease group, cell group and cell class (v2)

MEF2B BRME1 TNFRSF18 TIE1 CABIN1

5.42e-051541175187b9d4eb0e98c506034735601ead480ff00bd57
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IL12RB2 TNFRSF18 LACTB TIGIT EBI3

6.30e-051591175b05fda31b77536a1878f55d3199563b53f9420b2
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSMD3 GLP2R ADAM2 HEPHL1 UNC80

6.89e-051621175bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellsevere-unassigned|World / disease stage, cell group and cell class

BRME1 F12 PABPC1L NEURL4 PCOLCE

7.30e-051641175b3a45c150df6594debeeca400cc58d30ef662756
ToppCellsevere-unassigned|severe / disease stage, cell group and cell class

BRME1 F12 PABPC1L NEURL4 PCOLCE

7.51e-051651175f9ddd547992fec065d539a1d0305acba8fc7d79c
ToppCellnucseq-Immune-Hematopoietic-Granulocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPECC1 RAB44 TPSD1 PARP4 CACNA1H

7.51e-05165117537615622c736e43260c38016e7c9e565ac97a3e8
ToppCellnucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPECC1 RAB44 TPSD1 PARP4 CACNA1H

7.51e-051651175640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCellnucseq-Immune-Hematopoietic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPECC1 RAB44 TPSD1 PARP4 CACNA1H

7.51e-051651175f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BIN1 TNFRSF18 TIGIT GUCY2D KIR2DL4

7.73e-05166117562523e635784512b3261b672beaa7747cb9d114a
ToppCell10x5'-blood-Lymphocytic_NK-NK_CD56bright_CD16-|blood / Manually curated celltypes from each tissue

JCAD IL12RB2 TNFRSF18 TIE1 KIR2DL4

7.73e-051661175ba42349a68b22e91a0340bda1ccecd6c7592392f
ToppCellfacs-Skin-Anagen-24m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB44 ESRP2 ADAD2 SUSD2 HEPHL1

7.95e-05167117502c89069dcd0e87f7502e32b14e7cbd3cab81a09
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CARMIL3 CACNA1H GREB1 UNC80 SLC38A8

7.95e-051671175c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

JCAD IL12RB2 BACH2 TNFRSF18 KIR2DL4

8.41e-051691175e9c0e0f4c421c7bdbf1a7e33002f3cf22ea307cb
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

JCAD IL12RB2 BACH2 TNFRSF18 KIR2DL4

8.41e-051691175d375a1df1ecc938f66bad92e54b8cda26ca9c472
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

JCAD IL12RB2 BACH2 TNFRSF18 KIR2DL4

8.41e-05169117558f805c0be507bd5fadc9ea3555032daabbc8ab8
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

BIN1 SYNM PASK TIGIT PARD6A

8.41e-051691175bea8aba1f3cc3d0e8d448c1c45f5354d26ebf850
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFRSF18 FBN2 TIGIT SUSD2 LY75

8.65e-051701175064786c1f1ad7665358964765910b0ad46d14685
ToppCelldroplet-Lung-nan-18m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFRSF18 FBN2 TIGIT SUSD2 LY75

8.65e-0517011756725747df336697708b94999b3ebb40f1721da16
ToppCellNS-critical-d_0-4-Lymphoid-B_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ZNF22-AS1 IL17RC KRBA1 FADS3 LY75

8.89e-051711175bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-5|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PPRC1 BACH2 SH2B2 PARD6A PABPC1L

8.89e-05171117523b3120706bb9c20b9214fe3760c6d7a84f1e749
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-regulatory_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TNFRSF18 FBN2 TIGIT SUSD2 LY75

8.89e-05171117510492832db8ebc3cf85503c441f33bd94df9458e
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TNFRSF18 FBN2 TIGIT SUSD2 LY75

8.89e-0517111757c0a1b0676f6749ee710c6bdeca6d6f7fac79b69
ToppCellCOVID-19_Severe-NK_CD56bright|COVID-19_Severe / Disease condition and Cell class

IL12RB2 TNFRSF18 SPECC1 TIE1 KIR2DL4

8.89e-0517111755810f790012a0750ca3378595514f66a99f123be
ToppCellCOPD-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

IL12RB2 BACH2 TNFRSF18 SPECC1 KIR2DL4

9.39e-0517311754a0043b29f8ede5a74bdb38cbf2c70e12b25e130
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHG2 ADCY6 FADS3 AOC3 PCOLCE

9.39e-0517311752415b6ff49f334da570577d4e93484d024a3dbd5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHG2 ADCY6 FADS3 AOC3 PCOLCE

9.39e-0517311752acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEF2B BACH2 CR2 EBI3 TMEM131L

9.39e-051731175b7e0193fd4983cb38d1bee441f608f73ee8743b9
ToppCellfacs-Lung-EPCAM-3m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR7 ADCY6 TMEM131L FOXH1 LY75

1.05e-041771175d445167dae956e641386f84ab3ae9f47c089e09a
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL12RB2 TAB2 TNFRSF18 DPF3 KIR2DL4

1.05e-04177117589e9ac601bc80bd33141da84056189950e563a1e
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR7 ADCY6 TMEM131L FOXH1 LY75

1.07e-0417811750b456ac768e026c3ecd5a9a4f43d6f126e7685a1
ToppCellCOVID-19_Mild-NK_CD56bright|COVID-19_Mild / Disease condition and Cell class

IL12RB2 TNFRSF18 SPECC1 TIE1 KIR2DL4

1.10e-04179117590e7a4af195aa2332b07a9f06cde63e72ff49255
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BACH2 TNFRSF18 TOE1 TIGIT KIR2DL4

1.10e-041791175db76edd368eeca05a2a5d407c3eb2f535ade0ce3
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Striatum / BrainAtlas - Mouse McCarroll V32

TNFRSF18 TIE1 GUCY2D LY75

1.11e-04941174858dda192747e71533736247bc9e135f763a8860
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Striatum / BrainAtlas - Mouse McCarroll V32

TNFRSF18 TIE1 GUCY2D LY75

1.11e-04941174901c4908d27a06c81853a02042cd331549e0e27d
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Striatum / BrainAtlas - Mouse McCarroll V32

TNFRSF18 TIE1 GUCY2D LY75

1.11e-049411749d1dfd534871da30bc25a42e36bed9826f6127d8
ToppCellmild_COVID-19-NK_CD56bright|mild_COVID-19 / disease group, cell group and cell class (v2)

IL12RB2 TNFRSF18 CSMD2 TIE1 KIR2DL4

1.13e-041801175d8b418edd807a51c0b5f4018b8b478dcc65892a7
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

KIF26A DPF3 SUSD2 AOC3 CACNA1H

1.13e-0418011757085a851807e6a833965e1366946db0bbc5174e2
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEF2B SUSD2 AOC3 CACNA1H RELT

1.13e-0418011754fb95ed39508bede5472dd36aeabe91b33631726
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

JCAD IL12RB2 TNFRSF18 TIE1 KIR2DL4

1.16e-0418111759c4f9abb9335da2b07644bca8faff1baa1bb9f5b
ToppCellCOVID-19-APC-like-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

HTR7 SPECC1 EBI3 RELT LY75

1.22e-041831175703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SH3BP2 TNFRSF18 FOXN3 TIGIT EBI3

1.22e-0418311753cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCellCOVID-19-APC-like|COVID-19 / group, cell type (main and fine annotations)

HTR7 SPECC1 EBI3 RELT LY75

1.22e-041831175b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN CSMD3 FBN2 KCNQ2 UNC80

1.25e-0418411752cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR1B PLEKHG2 FADS3 AOC3 PCOLCE

1.25e-04184117589ae8bf1a6c2d355d279d23a5e24a08d9ec2334e
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN CSMD3 FBN2 KCNQ2 UNC80

1.25e-041841175ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN CSMD3 FBN2 KCNQ2 UNC80

1.25e-0418411752b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR1B PLEKHG2 FADS3 AOC3 PCOLCE

1.25e-04184117534c84ac9a32eaf96f45b79485119cad65905817d
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-Treg|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL12RB2 TAB2 TNFRSF18 FOXN3 TIGIT

1.29e-041851175a86a3a1a187a4d8d7762bc6d3dcb22c982178d22
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNM OBSCN CCN5 AOC3 CACNA1H

1.32e-041861175888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL12RB2 TNFRSF18 PASK TIGIT KCNQ2

1.35e-041871175c0a18ab7d88420e20e478ccdce6a2cb0a60a7824
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_NK-NK_CD56bright_CD16-|lymph-node_spleen / Manually curated celltypes from each tissue

IL12RB2 TNFRSF18 TIGIT TIE1 KIR2DL4

1.35e-0418711759000241566f48e435db9409b7255db68b68f6059
ToppCell5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL12RB2 TNFRSF18 PASK TIGIT KCNQ2

1.35e-041871175442b7bf6bc17fc2d38bccd678be8994b0ead374f
ToppCell5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL12RB2 TNFRSF18 PASK TIGIT KCNQ2

1.35e-041871175fda45c15806f34e45d44bb2e1d144591bc6eaa02
ToppCellHealthy_donor-NK_CD56bright|World / disease group, cell group and cell class (v2)

IL12RB2 TNFRSF18 RTKN TIE1 KIR2DL4

1.39e-0418811758ee359199c61c3b5b498ac35148390db5cc1a836
ToppCell(0)_NK_CD160pos|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

TNFRSF18 SPECC1 TIGIT TIE1 KIR2DL4

1.42e-041891175713991025bb92d38cb0507ff01fd91b48c8af45a
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

JCAD IL12RB2 TNFRSF18 TIE1 KIR2DL4

1.42e-0418911753e148accffc6ab249fb0dff7f3bf5a7fff9da773
ToppCellSevere-Treg|World / Disease group and Cell class

IL12RB2 TNFRSF18 PLEKHG4B TIGIT EBI3

1.49e-0419111750a80b8c317e8da4d4722cfd13cdabc32b58021eb
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BACH2 FOXN3 TMEM132E TMEM131L AGBL1

1.49e-041911175318323a12029a7992f16382cb0c186f5b2e1ca47
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNM OBSCN CCN5 AOC3 CACNA1H

1.49e-0419111751626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNM OBSCN CCN5 AOC3 CACNA1H

1.49e-041911175716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BACH2 FOXN3 TMEM132E TMEM131L AGBL1

1.49e-0419111754aa29337f4d2528577bb90dc4abfb6eab93e120f
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR7 ADCY6 FADS3 AOC3 CACNA1H

1.53e-04192117588472b99970ba0decbf87164fc241a1c77b3b389
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-T_reg|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TNFRSF18 KRBA1 GPR61 TIGIT KCNQ2

1.53e-04192117594e11f68767a899cbcc6984f9398877c1e464abc
ToppCellControl-NK_CD56bright|Control / Disease condition and Cell class

IL12RB2 TNFRSF18 SPECC1 TIE1 KIR2DL4

1.57e-0419311758b1e7a226a6057e1097c1525984127b54e823876
ToppCellMild_COVID-19-T/NK-NK|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

IL12RB2 BACH2 TNFRSF18 TIE1 KIR2DL4

1.57e-0419311759c455d9d845fa230e9a61d9a5f9d6a2ccf5d7350
ToppCellILEUM-inflamed-(1)_T_cell-(1)_Tregs|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IL12RB2 TNFRSF18 TIGIT EBI3 LY75

1.60e-0419411750396457834bbfed8d0b9b2ddaaecd9f28e1d56ed
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNM CCN5 AOC3 CACNA1H PCOLCE

1.60e-041941175f95935153bd2c4c3c7b2b729da6f7e98b45fed79
ToppCell10x5'-lymph-node_spleen-Lymphocytic_NK-NK_CD56bright_CD16-|lymph-node_spleen / Manually curated celltypes from each tissue

IL12RB2 TNFRSF18 SPECC1 TIE1 KIR2DL4

1.60e-0419411758a596f25f6bfa5baaa2f52d80ad92f2925713398
ToppCellBAL-Mild-Lymphocyte-T/NK-NK_cell-NK|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL12RB2 BACH2 TNFRSF18 TIE1 KIR2DL4

1.64e-04195117590c77b7f245b1bf80ba293583f8fe343b14c7f67
ToppCellBAL-Mild-Lymphocyte-T/NK-NK_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL12RB2 BACH2 TNFRSF18 TIE1 KIR2DL4

1.64e-0419511754eb13aa9fc496caca6e0a4fb80d11a60cf2511b0
ToppCellBAL-Mild-Lymphocyte-T/NK-NK_cell-NK-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL12RB2 BACH2 TNFRSF18 TIE1 KIR2DL4

1.64e-041951175234666fb7a1fd7e33bb7e54fd4004649ce22de70
ToppCell3'_v3-blood-Lymphocytic_NK-NK_CD56bright_CD16-|blood / Manually curated celltypes from each tissue

IL12RB2 MKNK2 TNFRSF18 TIE1 KIR2DL4

1.64e-0419511751470f562ebcfe7da367964ecfd6c7f43bcdb4a73
ToppCellBAL-Mild-Lymphocyte-T/NK-NK_cell-NK|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IL12RB2 BACH2 TNFRSF18 TIE1 KIR2DL4

1.64e-041951175f0fb039f3d2e36acb258afb8b6d2fed20c395c36
ToppCellBAL-Mild-Lymphocyte-T/NK-NK_cell|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IL12RB2 BACH2 TNFRSF18 TIE1 KIR2DL4

1.64e-041951175c7743d8c57584d29cca69c6405f1df6718174582
ToppCellBAL-Mild-Lymphocyte-T/NK-NK_cell-NK-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL12RB2 BACH2 TNFRSF18 TIE1 KIR2DL4

1.64e-04195117589d832d1715f2720caa8cdd1e7ef847d79642556
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHG2 FADS3 SUSD2 AOC3 PCOLCE

1.68e-041961175184104cbea0461dd2757668ab9755948ac7b585a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHG2 FADS3 SUSD2 AOC3 PCOLCE

1.68e-041961175bebb20dc210576101c317011e3afb59798f5d255
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHG2 FADS3 SUSD2 AOC3 PCOLCE

1.68e-0419611758114e98923096c54b6834f21550c3061bab6773d
Diseasesmall cell lung carcinoma

IL17RC FOXN3 ADAD2 A2ML1

2.85e-04801164EFO_0000702
Diseasediverticulitis

JCAD TAB2 ADCY6

4.17e-04371163EFO_1001460
Diseaseinterleukin 27 receptor subunit alpha measurement

BRME1 EBI3

4.22e-0481162EFO_0008183
Diseasetryptase beta-2 measurement

TPSD1 CACNA1H

5.42e-0491162EFO_0008306
DiseaseThromboembolism

F12 LPA

9.86e-04121162C0040038
DiseaseMetastatic melanoma

PASK GUCY2D PRKDC

1.27e-03541163C0278883
Diseasenasopharynx carcinoma (is_implicated_in)

CR2 TP53

1.56e-03151162DOID:9261 (is_implicated_in)
Diseasecreatinine measurement

DCDC1 OBSCN SLC44A4 SH2B2 KIAA1614 F12 LACTB DPF3 LPA TMEM131L UNC80

1.90e-0399511611EFO_0004518
DiseaseHypogammaglobulinemia

BACH2 CR2

2.00e-03171162C0086438
Diseaseischemia (biomarker_via_orthology)

HTR1B TP53

2.25e-03181162DOID:326 (biomarker_via_orthology)
DiseaseX-24309 measurement

FBF1 DPF3

2.78e-03201162EFO_0800872
Diseaseserum alanine aminotransferase measurement, response to combination chemotherapy

HTR1B CSMD2 GREB1

2.79e-03711163EFO_0004735, EFO_0007965
Diseasethyroid peroxidase antibody measurement

BACH2 CSMD2 TMEM131L

2.90e-03721163EFO_0005666
Diseaseserum non-albumin protein measurement

TAB2 FADS3 LPA GUCY2D TMEM131L TP53

3.09e-033611166EFO_0004568
Diseaseanxiety disorder (implicated_via_orthology)

HTR1B HTR7

3.36e-03221162DOID:2030 (implicated_via_orthology)
DiseaseLeber Congenital Amaurosis

PCYT1A GUCY2D

3.36e-03221162C0339527
Diseasefree androgen index

PCYT1A FOXN3 ADCY6 ZNF469 MYPOP GREB1

3.67e-033741166EFO_0007005

Protein segments in the cluster

PeptideGeneStartEntry
PPGPPWAPSNTSENC

BACH2

776

Q9BYV9
AQCAPPPPAGSETWV

HTR1B

6

P28222
PAQAQSAWGPAPAPA

ADAD2

36

Q8NCV1
PVWNNPRPVCTAPCG

CSMD2

1606

Q7Z408
FWQPSPPVCIAPCGG

CSMD3

1576

Q7Z407
TPAGPPRCPWQDDAF

ADCY6

56

O43306
PPDCSVQSDLWPGGS

ADAM2

641

Q99965
PWASPSAGPLPASRC

GRM2

486

Q14416
WDGASQDCPPLPAGV

FBXO34

366

Q9NWN3
DQCPVSGPWDFPQPL

A2ML1

631

A8K2U0
ASPSPEPWTPGHGAC

SH3BP2

301

P78314
WPGVCVSRTSPTPPE

SPECC1

801

Q5M775
AFPDVWGHCPPPTTQ

AGBL1

531

Q96MI9
CPSVSPSAQPWTHPG

AOC3

41

Q16853
AAAPAPEWCPLAAQP

RASSF7

356

Q02833
PPGISCSWHIIAPPD

PCOLCE

181

Q15113
QLCWSPPPTPRATSG

RAB44

386

Q7Z6P3
PPAGNIGTASWSDPC

NOBOX

586

O60393
WSPAAPENSPTCSPE

MON1B

76

Q7L1V2
SPWAPSGDCAMESPP

MAPK7

421

Q13164
PIAIWVSCGEPFLPP

DCDC1

1536

M0R2J8
SASSPCPQAWGPPGV

IL11RA

21

Q14626
SGWSSPLLPAPVCNP

PASK

116

Q96RG2
SWVQSPPGPASCQPG

KRBA1

336

A5PL33
EGAPSVPPGCSLQWS

GPR61

186

Q9BZJ8
PQCPSTSPAYWGVAP

FOXH1

301

O75593
VSSDPKSPWPACGPR

NCKAP5L

1056

Q9HCH0
WSPESPSAPDGGCPQ

GREB1

316

Q4ZG55
SAPGPDPSCWFDPNN

GUCY2D

441

Q02846
LNPPVAEPPEGSWSC

DPF3

346

Q92784
EPPPVGWQCPGCTFI

RBCK1

191

Q9BYM8
SDWQGPGCSVPVPAN

ATRN

311

O75882
EPSQPESGAQACWPA

ATXN1L

636

P0C7T5
CNQPPSAWSSHPPTG

JCAD

96

Q9P266
QSLAPWSPQTPAPPC

LACTB

86

P83111
NPACPWTVLPAGDLP

IL12RB2

781

Q99665
QPTASLCPEGWAPTP

KIAA1614

796

Q5VZ46
DPPSLGNNSSPCWSP

CARMIL3

1096

Q8ND23
SSTIPDFWGLPSCPP

C9orf131

816

Q5VYM1
WPFSGKTSPPCSPAN

PCYT1A

336

P49585
AAPPVQCPPSTSWQP

KCNQ2

706

O43526
PWVQGCAPENTLPTP

MKNK2

366

Q9HBH9
VCDLGWTSDLPPPTP

MEGF8

1136

Q7Z7M0
TVCFPPDPTAPASAW

MEGF8

2701

Q7Z7M0
SPKPDDPCPEGWQSF

LY75

636

O60449
PTWGPCPGEVAAVAP

KIF26A

1171

Q9ULI4
PPPWGDCSSASLNPN

ASIC3

276

Q9UHC3
CPVQLWVDSTPPPGT

TP53

141

P04637
WIPQSASCPTGPPQN

PARP4

1376

Q9UKK3
YGCGPVTPTQPAPRW

PABPC1L

421

Q4VXU2
PIPCSSPGPWQSLCG

MEF2B

301

Q02080
RPSPDSPWGQPAPFC

OBSCN

7021

Q5VST9
QPPSSNGLSQGPPCW

PARD6A

291

Q9NPB6
PFCSAWPSAVVPQGG

KIR2DL4

31

Q99706
TRWCSQPPTGLDPSP

FBF1

1076

Q8TES7
WPHSSPGNVSVPCPS

GLP2R

106

O95838
PCWPGPSSHANGDPV

BRME1

566

Q0VDD7
APTSSPAEPHCWPAE

CABIN1

2041

Q9Y6J0
SWSGPSPQCLRSPPV

CR2

771

P20023
GFPSPCPSIWDVPQQ

DBX2

271

Q6ZNG2
CPQAYQSTSGPPIWP

FOXN3

221

O00409
TPVIQDNPSGWGPCA

EIF3D

6

O15371
PIAVDCSWTLPPAPN

EBI3

41

Q14213
SSLPPGVPCPEWSTA

CCN5

186

O76076
QGCPDEPWPSATPCG

BAHD1

276

Q8TBE0
EPWPSATPCGPSVQP

BAHD1

281

Q8TBE0
NPDPVAAPWCYTTDP

LPA

991

P08519
PTAGSGEWVTLPCPD

GHRHR

66

Q02643
RSGPGPSDPNCIPWV

HEPHL1

871

Q6MZM0
PEQWQLWPPVPSGCA

GPR156

721

Q8NFN8
PTPQVCVSSCPEDPW

SLC44A4

111

Q53GD3
CFPWTNVTPPALPGI

SLC44A4

181

Q53GD3
WSRPGPAQSDPGQCP

CCDC174

411

Q6PII3
VWVPGPTDDCCPAKP

HERVK_113

131

Q902F9
AWNKPCEPCPTPGTA

FBN2

1771

P35556
PPAGVPPAASSQVWA

C1orf127

226

Q8N9H9
WPSQTAEPGPAQPAE

BIN1

446

O00499
SSACPWQPTAEPHGP

CACNA1H

2106

O95180
EGPAQPGAPLPTFCW

FADS3

11

Q9Y5Q0
GAYAVPPTCSVPWAP

PPRC1

951

Q5VV67
ESVCWGPPPAASPLK

NEURL4

1321

Q96JN8
GDPCQPLVPPLSWEN

IL17RC

406

Q8NAC3
LSCPPAAPGPWAAEA

IRGQ

61

Q8WZA9
PQEPPAGTACAIAGW

PRSS56

216

P0CW18
RPGPQPWCATTPNFD

F12

66

P00748
PDPSPPWSTQVCQGP

RUSC2

611

Q8N2Y8
CSPASVAPAPDWTHP

RTKN

496

Q9BST9
PVVSCGWLAPPPNGQ

SUSD2

721

Q9UGT4
PASETFPPGMPCWVT

TPSD1

151

Q9BZJ3
PQGSPPRSPWGDCAE

TMEM105

56

Q8N8V8
IPCNCSAWPSPGLQP

SOX21

236

Q9Y651
PGDLWPTPPVCVTSS

TMEM131L

1406

A2VDJ0
SSPAPCSPPESWGRQ

TMEM200C

351

A6NKL6
WGCPDVAGPTRPTAP

TMEM132E

1046

Q6IEE7
CPEAWGSPEPGPAES

SYNM

1196

O15061
SQPGPWTTCPASNPL

TAB2

251

Q9NYJ8
PVTCPICVSLPWGDP

RNF138

186

Q8WVD3
ELAPPAPSAPSWGCL

SHKBP1

606

Q8TBC3
GRPTFGWSPEPCDSP

SETD1B

466

Q9UPS6
GWSPEPCDSPGTPTL

SETD1B

471

Q9UPS6
AADPAADPCPWPGSL

ESRP2

16

Q9H6T0
CDSLLSGTPPAPQPW

SLC38A8

131

A6NNN8
GPAVCIPGQPIPTTW

STRC

1116

Q7RTU9
PAPTWDAPPDNASGC

HTR7

56

P34969
PVISCPPLTPDWGVQ

PAICS

346

P22234
PEFPPPDRTLGCWAT

RSPH3

51

Q86UC2
VPMFDPPWVPQCSGS

UNC80

1691

Q8N2C7
PPWVPQCSGSVQDPI

UNC80

1696

Q8N2C7
PPMPWNLPAGVDCTT

SCAF1

1086

Q9H7N4
AWGPPTLMTTDCPEP

TIE1

531

P35590
WMGPLDPEACPSSPV

PLEKHG4B

531

Q96PX9
DNMCWPAPSQIPPVS

XRN1

1426

Q8IZH2
QGSECRAPNPCWPSP

STAB1

226

Q9NY15
PTPPAAPASPACWSD

SH2B2

526

O14492
QEEWSPSAPSPPGSC

TIGIT

186

Q495A1
AAEEEAQPPSWSCGP

PRKDC

3391

P78527
AQPPSWSCGPAAGVI

PRKDC

3396

P78527
PPGPQQLLACSPAWA

ZNF469

2131

Q96JG9
AVCVPGSPPAEPLGW

TNFRSF18

151

Q9Y5U5
NAAWDPTTGAQPPAP

ZNF688

156

P0C7X2
WGVPRVPCQPCSWAP

RELT

101

Q969Z4
GPDPVCSQPIQPLSW

PLEKHG2

1066

Q9H7P9
LRSPCAPPQPSWPCS

ZNF22-AS1

106

Q5T742
PESWGFLCPVHTPDG

POLR1B

491

Q9H9Y6
VSQGPQPCSSGPWLP

TOE1

456

Q96GM8
SASPQAPWPKPGCAS

UNQ6493/PRO21345

96

Q6UXR8
AGAAPCPPNPANSWV

KIAA1522

486

Q9P206
CPPNPANSWVPGLSP

KIAA1522

491

Q9P206
PWARPSCTPQEGGCP

MYPOP

181

Q86VE0