Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	P-type sodium transporter activity	ATP1A1 ATP1A3 ATP1A4	1.34e-05	10	98	3	GO:0008554
GeneOntologyMolecularFunction	P-type sodium:potassium-exchanging transporter activity	ATP1A1 ATP1A3 ATP1A4	1.34e-05	10	98	3	GO:0005391
GeneOntologyMolecularFunction	P-type potassium transmembrane transporter activity	ATP1A1 ATP1A3 ATP1A4	1.84e-05	11	98	3	GO:0008556
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC8A1 PKD2 CACNA1I CACNA1H ATP1A1 ATP1A3 ATP1A4	2.15e-05	171	98	7	GO:0015081
GeneOntologyMolecularFunction	P-type transmembrane transporter activity	ATP13A2 ATP1A1 ATP1A3 ATP1A4	2.85e-05	36	98	4	GO:0140358
GeneOntologyMolecularFunction	P-type ion transporter activity	ATP13A2 ATP1A1 ATP1A3 ATP1A4	2.85e-05	36	98	4	GO:0015662
GeneOntologyMolecularFunction	low voltage-gated calcium channel activity	CACNA1I CACNA1H	7.13e-05	3	98	2	GO:0008332
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC8A1 SLC30A5 SLC12A4 KCNH1 PKD2 CACNA1I CACNA1H ATP1A1 ATP1A3 ATP1A4	9.57e-05	465	98	10	GO:0046873
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	SLC12A4 KCNH1 PKD2 ATP1A1 ATP1A3 ATP1A4	1.74e-04	167	98	6	GO:0015079
GeneOntologyMolecularFunction	phosphatidic acid binding	RAPGEF6 ATP13A2 RAPGEF2	2.15e-04	24	98	3	GO:0070300
GeneOntologyMolecularFunction	ATPase-coupled monoatomic cation transmembrane transporter activity	ATP13A2 ATP1A1 ATP1A3 ATP1A4	2.45e-04	62	98	4	GO:0019829
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	PKD2 CACNA1I CACNA1H	2.75e-04	26	98	3	GO:0005248
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	ATP13A2 SLC8A1 SLC30A5 SLC12A4 KCNH1 PKD2 CACNA1I CACNA1H ATP1A1 ATP1A3 ATP1A4	4.11e-04	664	98	11	GO:0008324
GeneOntologyMolecularFunction	steroid hormone binding	ATP1A1 ATP1A3	4.93e-04	7	98	2	GO:1990239
GeneOntologyMolecularFunction	active transmembrane transporter activity	ATP13A2 SLC8A1 SLC30A5 SLC12A4 SLC16A4 SLC22A4 ATP1A1 ATP1A3 ATP1A4	5.64e-04	477	98	9	GO:0022804
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	ATP13A2 SLC8A1 SLC30A5 SLC12A4 ATP1A1 ATP1A3 ATP1A4	7.08e-04	301	98	7	GO:0022853
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC8A1 SLC30A5 SLC12A4 KCNH1 PKD2 CACNA1I CACNA1H ATP1A1 ATP1A3 ATP1A4	1.02e-03	627	98	10	GO:0022890
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	DNAH3 TDRD9 ATP13A2 DNAH7 RGS13 ATP1A1 ATP1A3 ATP1A4 ATL2 AGAP1 AGAP3	1.46e-03	775	98	11	GO:0017111
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	PKD2 CACNA1I CACNA1H	1.49e-03	46	98	3	GO:0005245
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	ATP13A2 SLC8A1 SLC30A5 SLC12A4 KCNH1 PKD2 CACNA1I CACNA1H ATP1A1 ATP1A3 ATP1A4	1.75e-03	793	98	11	GO:0015075
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ATP13A2 ATP1A1 ATP1A3 ATP1A4	2.05e-03	109	98	4	GO:0042626
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1I CACNA1H	2.09e-03	14	98	2	GO:0008331
GeneOntologyMolecularFunction	sodium channel activity	PKD2 CACNA1I CACNA1H	2.13e-03	52	98	3	GO:0005272
GeneOntologyMolecularFunction	pyrophosphatase activity	DNAH3 TDRD9 ATP13A2 DNAH7 RGS13 ATP1A1 ATP1A3 ATP1A4 ATL2 AGAP1 AGAP3	2.71e-03	839	98	11	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DNAH3 TDRD9 ATP13A2 DNAH7 RGS13 ATP1A1 ATP1A3 ATP1A4 ATL2 AGAP1 AGAP3	2.73e-03	840	98	11	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DNAH3 TDRD9 ATP13A2 DNAH7 RGS13 ATP1A1 ATP1A3 ATP1A4 ATL2 AGAP1 AGAP3	2.73e-03	840	98	11	GO:0016818
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH3 DNAH7	3.47e-03	18	98	2	GO:0008569
GeneOntologyBiologicalProcess	inorganic ion import across plasma membrane	SLC8A1 SLC30A5 SLC12A4 CACNA1I CACNA1H ATP1A1 ATP1A3 ATP1A4	3.29e-07	142	96	8	GO:0099587
GeneOntologyBiologicalProcess	inorganic cation import across plasma membrane	SLC8A1 SLC30A5 SLC12A4 CACNA1I CACNA1H ATP1A1 ATP1A3 ATP1A4	3.29e-07	142	96	8	GO:0098659
GeneOntologyBiologicalProcess	sodium ion export across plasma membrane	SLC8A1 ATP1A1 ATP1A3 ATP1A4	1.00e-06	17	96	4	GO:0036376
GeneOntologyBiologicalProcess	import across plasma membrane	SLC8A1 SLC30A5 SLC12A4 SLC22A4 CACNA1I CACNA1H ATP1A1 ATP1A3 ATP1A4	1.27e-06	230	96	9	GO:0098739
GeneOntologyBiologicalProcess	sodium ion transport	SLC8A1 SLC22A4 PKD2 CACNA1I CACNA1H ATP1A1 ATP1A3 ATP1A4 UTRN	5.50e-06	275	96	9	GO:0006814
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	SLC8A1 PKD2 CACNA1I CACNA1H ATP1A1 ATP1A3 ATP1A4 UTRN	5.80e-06	208	96	8	GO:0035725
GeneOntologyBiologicalProcess	intracellular sodium ion homeostasis	SLC8A1 ATP1A1 ATP1A3 ATP1A4	1.10e-05	30	96	4	GO:0006883
GeneOntologyBiologicalProcess	establishment or maintenance of transmembrane electrochemical gradient	ATP1A1 ATP1A3 ATP1A4	1.57e-05	11	96	3	GO:0010248
GeneOntologyBiologicalProcess	potassium ion homeostasis	SLC12A4 ATP1A1 ATP1A3 ATP1A4	2.59e-05	37	96	4	GO:0055075
GeneOntologyBiologicalProcess	brain-derived neurotrophic factor receptor signaling pathway	TIAM1 RAPGEF2 ATP1A3	3.43e-05	14	96	3	GO:0031547
GeneOntologyBiologicalProcess	intracellular potassium ion homeostasis	ATP1A1 ATP1A3 ATP1A4	6.34e-05	17	96	3	GO:0030007
GeneOntologyBiologicalProcess	detection of nodal flow	TMEM107 PKD2	6.41e-05	3	96	2	GO:0003127
GeneOntologyBiologicalProcess	potassium ion import across plasma membrane	SLC12A4 ATP1A1 ATP1A3 ATP1A4	9.31e-05	51	96	4	GO:1990573
GeneOntologyBiologicalProcess	sodium ion homeostasis	SLC8A1 ATP1A1 ATP1A3 ATP1A4	9.31e-05	51	96	4	GO:0055078
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	TM9SF4 ATP13A2 BMP6 SLC8A1 SLC30A5 SLC12A4 KCNH1 PKD2 ELANE ATP1A1 ATP1A3 ATP1A4	1.05e-04	705	96	12	GO:0055080
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	TM9SF4 ATP13A2 BMP6 SLC8A1 SLC30A5 SLC12A4 KCNH1 PKD2 ELANE ATP1A1 ATP1A3 ATP1A4	1.23e-04	717	96	12	GO:0050801
GeneOntologyBiologicalProcess	intracellular monoatomic cation homeostasis	TM9SF4 ATP13A2 BMP6 SLC8A1 SLC30A5 KCNH1 PKD2 ELANE ATP1A1 ATP1A3 ATP1A4	1.27e-04	611	96	11	GO:0030003
GeneOntologyBiologicalProcess	inorganic ion homeostasis	ATP13A2 BMP6 SLC8A1 SLC30A5 SLC12A4 KCNH1 PKD2 ELANE ATP1A1 ATP1A3 ATP1A4	1.49e-04	622	96	11	GO:0098771
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	TM9SF4 ATP13A2 BMP6 SLC8A1 SLC30A5 KCNH1 PKD2 ELANE ATP1A1 ATP1A3 ATP1A4	1.49e-04	622	96	11	GO:0006873
GeneOntologyBiologicalProcess	response to glycoside	ATP1A1 ATP1A3	2.12e-04	5	96	2	GO:1903416
GeneOntologyBiologicalProcess	cell communication by electrical coupling involved in cardiac conduction	SLC8A1 ATP1A1 ATP1A3	2.35e-04	26	96	3	GO:0086064
GeneOntologyCellularComponent	sodium:potassium-exchanging ATPase complex	ATP1A1 ATP1A3 ATP1A4	2.26e-05	12	100	3	GO:0005890
GeneOntologyCellularComponent	photoreceptor inner segment membrane	ATP1A1 ATP1A3	1.35e-04	4	100	2	GO:0060342
GeneOntologyCellularComponent	protein complex involved in cell adhesion	LAMA1 ITGB7 NRXN1 TNN	1.83e-04	59	100	4	GO:0098636
GeneOntologyCellularComponent	sarcolemma	SLC8A1 SVIL CACNA1H ATP1A1 ATP1A3 UTRN	3.06e-04	190	100	6	GO:0042383
Domain	Cation_ATPase_N	ATP13A2 ATP1A1 ATP1A3 ATP1A4	2.23e-06	18	100	4	SM00831
Domain	ATPase_P-typ_cation-transptr_N	ATP13A2 ATP1A1 ATP1A3 ATP1A4	2.82e-06	19	100	4	IPR004014
Domain	P-type_ATPase_IIC	ATP1A1 ATP1A3 ATP1A4	2.94e-06	6	100	3	IPR005775
Domain	-	ATP13A2 ATP1A1 ATP1A3 ATP1A4	2.48e-05	32	100	4	3.40.1110.10
Domain	-	ATP13A2 ATP1A1 ATP1A3 ATP1A4	2.48e-05	32	100	4	2.70.150.10
Domain	TMEM191C	TMEM191C TMEM191B	2.84e-05	2	100	2	PF15194
Domain	TMEM191B/C	TMEM191C TMEM191B	2.84e-05	2	100	2	IPR028186
Domain	ATPase_P-typ_cyto_domN	ATP13A2 ATP1A1 ATP1A3 ATP1A4	3.57e-05	35	100	4	IPR023299
Domain	P_typ_ATPase	ATP13A2 ATP1A1 ATP1A3 ATP1A4	4.00e-05	36	100	4	IPR001757
Domain	ATPase_P-typ_P_site	ATP13A2 ATP1A1 ATP1A3 ATP1A4	4.00e-05	36	100	4	IPR018303
Domain	ATPASE_E1_E2	ATP13A2 ATP1A1 ATP1A3 ATP1A4	4.00e-05	36	100	4	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP13A2 ATP1A1 ATP1A3 ATP1A4	4.46e-05	37	100	4	IPR008250
Domain	E1-E2_ATPase	ATP13A2 ATP1A1 ATP1A3 ATP1A4	4.46e-05	37	100	4	PF00122
Domain	HAD-like_dom	PHOSPHO2 ATP13A2 ATP1A1 ATP1A3 ATP1A4	6.55e-05	79	100	5	IPR023214
Domain	-	ATP1A1 ATP1A3 ATP1A4	7.93e-05	16	100	3	1.20.1110.10
Domain	ATPase_P-typ_TM_dom	ATP1A1 ATP1A3 ATP1A4	7.93e-05	16	100	3	IPR023298
Domain	VDCC_T_a1	CACNA1I CACNA1H	8.48e-05	3	100	2	IPR005445
Domain	EGF_2	FAT3 LAMA1 ITGB7 SNED1 NRXN1 MEGF9 TNN EPHA3	8.92e-05	265	100	8	PS01186
Domain	ATPase_P-typ_cation-transptr_C	ATP1A1 ATP1A3 ATP1A4	9.59e-05	17	100	3	IPR006068
Domain	Cation_ATPase_C	ATP1A1 ATP1A3 ATP1A4	9.59e-05	17	100	3	PF00689
Domain	Cation_ATPase_N	ATP1A1 ATP1A3 ATP1A4	1.15e-04	18	100	3	PF00690
Domain	fn3	SNED1 FNDC7 TNN ROS1 SDK1 EPHA3	2.36e-04	162	100	6	PF00041
Domain	EGF_1	FAT3 LAMA1 ITGB7 SNED1 NRXN1 MEGF9 TNN	4.43e-04	255	100	7	PS00022
Domain	FN3	SNED1 FNDC7 TNN ROS1 SDK1 EPHA3	4.80e-04	185	100	6	SM00060
Domain	ArfGap	ARAP3 AGAP1 AGAP3	4.92e-04	29	100	3	SM00105
Domain	ArfGap	ARAP3 AGAP1 AGAP3	4.92e-04	29	100	3	PF01412
Domain	ARFGAP	ARAP3 AGAP1 AGAP3	4.92e-04	29	100	3	PS50115
Domain	ArfGAP	ARAP3 AGAP1 AGAP3	4.92e-04	29	100	3	IPR001164
Domain	EGF-like_CS	FAT3 LAMA1 ITGB7 SNED1 NRXN1 MEGF9 TNN	5.09e-04	261	100	7	IPR013032
Domain	FN3	SNED1 FNDC7 TNN ROS1 SDK1 EPHA3	7.05e-04	199	100	6	PS50853
Domain	cNMP	RAPGEF6 KCNH1 RAPGEF2	7.90e-04	34	100	3	SM00100
Domain	cNMP_binding	RAPGEF6 KCNH1 RAPGEF2	7.90e-04	34	100	3	PF00027
Domain	-	IGSF10 SNED1 FNDC7 CD33 TNN ADGRF5 ROS1 SDK1 EBF4 CD200 EPHA3	8.37e-04	663	100	11	2.60.40.10
Domain	cNMP-bd_dom	RAPGEF6 KCNH1 RAPGEF2	8.61e-04	35	100	3	IPR000595
Domain	CNMP_BINDING_3	RAPGEF6 KCNH1 RAPGEF2	8.61e-04	35	100	3	PS50042
Domain	FN3_dom	SNED1 FNDC7 TNN ROS1 SDK1 EPHA3	9.10e-04	209	100	6	IPR003961
Domain	RA	RAPGEF6 ARAP3 RAPGEF2	9.35e-04	36	100	3	PF00788
Domain	RA	RAPGEF6 ARAP3 RAPGEF2	1.01e-03	37	100	3	PS50200
Domain	cNMP-bd-like	RAPGEF6 KCNH1 RAPGEF2	1.10e-03	38	100	3	IPR018490
Domain	LAM_G_DOMAIN	FAT3 LAMA1 NRXN1	1.10e-03	38	100	3	PS50025
Domain	VDCCAlpha1	CACNA1I CACNA1H	1.24e-03	10	100	2	IPR002077
Domain	Laminin_G_2	FAT3 LAMA1 NRXN1	1.27e-03	40	100	3	PF02210
Domain	RA_dom	RAPGEF6 ARAP3 RAPGEF2	1.27e-03	40	100	3	IPR000159
Domain	Ig-like_fold	IGSF10 SNED1 FNDC7 CD33 TNN ADGRF5 ROS1 SDK1 EBF4 CD200 EPHA3	1.39e-03	706	100	11	IPR013783
Domain	SAM_2	SFMBT1 ARAP3 EPHA3	1.57e-03	43	100	3	PF07647
Domain	Galactose-bd-like	LAMA1 CUL9 GLB1L2 EPHA3	1.63e-03	94	100	4	IPR008979
Domain	EGF	FAT3 LAMA1 SNED1 NRXN1 MEGF9 TNN	1.66e-03	235	100	6	SM00181
Domain	LamG	FAT3 LAMA1 NRXN1	1.68e-03	44	100	3	SM00282
Domain	Roc	AGAP1 AGAP3	2.13e-03	13	100	2	PF08477
Domain	MIRO-like	AGAP1 AGAP3	2.13e-03	13	100	2	IPR013684
Domain	-	RAPGEF6 KCNH1 RAPGEF2	2.16e-03	48	100	3	2.60.120.10
Domain	EGF-like_dom	FAT3 LAMA1 SNED1 NRXN1 MEGF9 TNN	2.22e-03	249	100	6	IPR000742
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH7	2.48e-03	14	100	2	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DNAH7	2.48e-03	14	100	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH7	2.48e-03	14	100	2	IPR013602
Domain	TUDOR	TDRD9 TDRD1	2.48e-03	14	100	2	PF00567
Domain	DHC_N2	DNAH3 DNAH7	2.48e-03	14	100	2	PF08393
Domain	MT	DNAH3 DNAH7	2.48e-03	14	100	2	PF12777
Domain	AAA_8	DNAH3 DNAH7	2.48e-03	14	100	2	PF12780
Domain	RmlC-like_jellyroll	RAPGEF6 KCNH1 RAPGEF2	2.57e-03	51	100	3	IPR014710
Domain	DHC_fam	DNAH3 DNAH7	2.85e-03	15	100	2	IPR026983
Domain	Dynein_heavy_dom	DNAH3 DNAH7	2.85e-03	15	100	2	IPR004273
Domain	Dynein_heavy	DNAH3 DNAH7	2.85e-03	15	100	2	PF03028
Domain	Channel_four-helix_dom	PKD2 CACNA1I CACNA1H	3.53e-03	57	100	3	IPR027359
Domain	-	PKD2 CACNA1I CACNA1H	3.53e-03	57	100	3	1.20.120.350
Domain	Laminin_G	FAT3 LAMA1 NRXN1	3.71e-03	58	100	3	IPR001791
Domain	RasGEFN	RAPGEF6 RAPGEF2	5.06e-03	20	100	2	SM00229
Pathway	REACTOME_ION_HOMEOSTASIS	SLC8A1 ATP1A1 ATP1A3 ATP1A4	1.46e-04	54	70	4	M27460
Pathway	REACTOME_ION_HOMEOSTASIS	SLC8A1 ATP1A1 ATP1A3 ATP1A4	1.46e-04	54	70	4	MM15202
Pathway	REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES	ATP13A2 ATP1A1 ATP1A3 ATP1A4	1.57e-04	55	70	4	M971
Pathway	REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES	ATP13A2 ATP1A1 ATP1A3 ATP1A4	1.81e-04	57	70	4	MM15643
Pathway	KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION	ATP1A1 ATP1A3 ATP1A4	1.93e-04	23	70	3	M4361
Pathway	REACTOME_MUSCLE_CONTRACTION	SLC8A1 CACNA1I CACNA1H ATP1A1 ATP1A3 ATP1A4	5.05e-04	203	70	6	M5485
Pathway	KEGG_CARDIAC_MUSCLE_CONTRACTION	SLC8A1 ATP1A1 ATP1A3 ATP1A4	6.33e-04	79	70	4	M17673
Pubmed	Identification of a VxP Targeting Signal in the Flagellar Na+ /K+ -ATPase.	ATP1A1 ATP1A3 ATP1A4	2.38e-08	3	101	3	26373354
Pubmed	Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.	ATP1A1 ATP1A3 ATP1A4	9.49e-08	4	101	3	21849490
Pubmed	Family of Na+,K+-ATPase genes. Intra-individual tissue-specific restriction fragment length polymorphism.	ATP1A1 ATP1A3 ATP1A4	9.49e-08	4	101	3	2887455
Pubmed	Multiple genes encode the human Na+,K+-ATPase catalytic subunit.	ATP1A1 ATP1A3 ATP1A4	2.37e-07	5	101	3	3035563
Pubmed	The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.	ATP1A1 ATP1A3 ATP1A4	4.72e-07	6	101	3	3036582
Pubmed	Differential involvement of Na(+),K(+)-ATPase isozymes in preimplantation development of the mouse.	ATP1A1 ATP1A3 ATP1A4	8.25e-07	7	101	3	10837135
Pubmed	Molecular genetics of Na,K-ATPase.	ATP1A1 ATP1A3 ATP1A4	8.25e-07	7	101	3	2158121
Pubmed	Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit.	SLC8A1 ATP1A1 ATP1A3	1.32e-06	8	101	3	19683723
Pubmed	The Na(+)-K(+)-ATPase alpha2-subunit isoform modulates contractility in the perinatal mouse diaphragm.	SLC8A1 ATP1A1 ATP1A3	1.97e-06	9	101	3	15253893
Pubmed	A T-type calcium channel required for normal function of a mammalian mechanoreceptor.	CACNA1I CACNA1H	8.35e-06	2	101	2	12808460
Pubmed	Immunohistochemical analyses of alpha1 and alpha3 Na+/K+-ATPase subunit expression in medulloblastomas.	ATP1A1 ATP1A3	8.35e-06	2	101	2	21498719
Pubmed	Rebound burst firing in the reticular thalamus is not essential for pharmacological absence seizures in mice.	CACNA1I CACNA1H	8.35e-06	2	101	2	25071191
Pubmed	Whole Exome Sequencing of Hemiplegic Migraine Patients Shows an Increased Burden of Missense Variants in CACNA1H and CACNA1I Genes.	CACNA1I CACNA1H	8.35e-06	2	101	2	36786913
Pubmed	All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides.	ATP1A1 ATP1A3	8.35e-06	2	101	2	11546672
Pubmed	Mutational alterations of TDRD 1, 4 and 9 genes in colorectal cancers.	TDRD9 TDRD1	8.35e-06	2	101	2	32036563
Pubmed	Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.	ATP1A1 ATP1A3	8.35e-06	2	101	2	24391932
Pubmed	The PDZ domain of the guanine nucleotide exchange factor PDZGEF directs binding to phosphatidic acid during brush border formation.	RAPGEF6 RAPGEF2	8.35e-06	2	101	2	24858808
Pubmed	[Mechanisms for linking high salt intake to vascular tone: role of Na(+) pump and Na(+)/Ca²(+) exchanger coupling].	SLC8A1 ATP1A1	8.35e-06	2	101	2	21048395
Pubmed	Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.	ATP1A1 ATP1A3	8.35e-06	2	101	2	23761886
Pubmed	The family of human Na+,K+-ATPase genes. A partial nucleotide sequence related to the alpha-subunit.	ATP1A1 ATP1A3	8.35e-06	2	101	2	3030810
Pubmed	Phosphatidic acid-dependent localization and basal de-phosphorylation of RA-GEFs regulate lymphocyte trafficking.	RAPGEF6 RAPGEF2	8.35e-06	2	101	2	32600317
Pubmed	RNG105 deficiency impairs the dendritic localization of mRNAs for Na+/K+ ATPase subunit isoforms and leads to the degeneration of neuronal networks.	ATP1A1 ATP1A3 CAPRIN1	2.23e-05	19	101	3	20861386
Pubmed	Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications.	ATP1A1 ATP1A3	2.50e-05	3	101	2	2822726
Pubmed	Na+/K+-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes.	ATP1A1 ATP1A3	2.50e-05	3	101	2	30819023
Pubmed	Ethanol inhibition of a T-type Ca²+ channel through activity of protein kinase C.	CACNA1I CACNA1H	2.50e-05	3	101	2	23488970
Pubmed	A splice form of polycystin-2, lacking exon 7, does not interact with polycystin-1.	RAPGEF6 PKD2	2.50e-05	3	101	2	16192288
Pubmed	T-type channels: release a brake, engage a gear.	CACNA1I CACNA1H	2.50e-05	3	101	2	26488564
Pubmed	Comprehensive behavioral analysis of mice deficient in Rapgef2 and Rapgef6, a subfamily of guanine nucleotide exchange factors for Rap small GTPases possessing the Ras/Rap-associating domain.	RAPGEF6 RAPGEF2	2.50e-05	3	101	2	29747665
Pubmed	Differential interactions of Na+ channel toxins with T-type Ca2+ channels.	CACNA1I CACNA1H	2.50e-05	3	101	2	18591418
Pubmed	Glycoprotein nonmetastatic melanoma protein B (GPNMB) promotes the progression of brain glioblastoma via Na+/K+-ATPase.	ATP1A1 ATP1A3	2.50e-05	3	101	2	27836549
Pubmed	Regulatory Variant rs2535629 in ITIH3 Intron Confers Schizophrenia Risk By Regulating CTCF Binding and SFMBT1 Expression.	SFMBT1 ITIH3	2.50e-05	3	101	2	34978167
Pubmed	Identification of the t-type calcium channel (Ca(v)3.1d) in developing mouse heart.	CACNA1I CACNA1H	2.50e-05	3	101	2	11230107
Pubmed	Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation.	CACNA1I CACNA1H	2.50e-05	3	101	2	28846697
Pubmed	Differential expression of Na+/K+-ATPase alpha-subunits in mouse hippocampal interneurones and pyramidal cells.	ATP1A1 ATP1A3	2.50e-05	3	101	2	17947306
Pubmed	Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.	CACNA1I CACNA1H	2.50e-05	3	101	2	33547341
Pubmed	Calmodulin regulates Cav3 T-type channels at their gating brake.	CACNA1I CACNA1H	2.50e-05	3	101	2	28972185
Pubmed	Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability.	CACNA1I CACNA1H	2.50e-05	3	101	2	11927664
Pubmed	Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders.	ATP1A1 ATP1A3	2.50e-05	3	101	2	19058785
Pubmed	Knockout of sodium pump α3 subunit gene (Atp1a3-/-) results in perinatal seizure and defective respiratory rhythm generation.	ATP1A1 ATP1A3	2.50e-05	3	101	2	28465228
Pubmed	Developmental cell-specific regulation of Na(+)-K(+)-ATPase alpha 1-, alpha 2-, and alpha 3-isoform gene expression.	ATP1A1 ATP1A3	2.50e-05	3	101	2	8203495
Pubmed	Na,K-ATPase and the role of alpha isoforms in behavior.	ATP1A1 ATP1A3	2.50e-05	3	101	2	18044013
Pubmed	Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na+/K+-ATPase.	ATP1A1 ATP1A3	2.50e-05	3	101	2	26988030
Pubmed	Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice.	CACNA1I CACNA1H	2.50e-05	3	101	2	11897840
Pubmed	The alpha 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca exchanger in heart.	SLC8A1 ATP1A1	2.50e-05	3	101	2	15485817
Pubmed	Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model.	ATP1A1 ATP1A3	2.50e-05	3	101	2	26911348
Pubmed	Cardiac glycosides induced toxicity in human cells expressing α1-, α2-, or α3-isoforms of Na-K-ATPase.	ATP1A1 ATP1A3	2.50e-05	3	101	2	25994790
Pubmed	Genome-wide identification of endothelial cell-enriched genes in the mouse embryo.	NRROS ARAP3 ADGRF5	4.04e-05	23	101	3	22535667
Pubmed	Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2.	ATP1A1 ATP1A3	4.99e-05	4	101	2	21731499
Pubmed	The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice.	ATP1A1 ATP1A3	4.99e-05	4	101	2	12458206
Pubmed	Regulation of cardiac myocyte contractility by phospholemman: Na+/Ca2+ exchange versus Na+ -K+ -ATPase.	SLC8A1 ATP1A1	4.99e-05	4	101	2	18708446
Pubmed	RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation.	RNF167 CASTOR1	4.99e-05	4	101	2	33594058
Pubmed	Testicular expression of TDRD1, TDRD5, TDRD9 and TDRD12 in azoospermia.	TDRD9 TDRD1	4.99e-05	4	101	2	32059713
Pubmed	The Na,K-ATPase alpha4 isoform from humans has distinct enzymatic properties and is important for sperm motility.	ATP1A1 ATP1A4	4.99e-05	4	101	2	16861705
Pubmed	Pharmacogenetics of antiepileptic drug efficacy in childhood absence epilepsy.	CACNA1I CACNA1H	4.99e-05	4	101	2	28165634
Pubmed	Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes.	ATP1A1 ATP1A3	4.99e-05	4	101	2	17446412
Pubmed	Na,K-ATPase expression in the mouse cochlea is not dependent on the mineralocorticoid receptor.	ATP1A1 ATP1A3	4.99e-05	4	101	2	11591489
Pubmed	Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1.	ATP1A1 ATP1A3	4.99e-05	4	101	2	19751721
Pubmed	Agrin regulation of alpha3 sodium-potassium ATPase activity modulates cardiac myocyte contraction.	ATP1A1 ATP1A3	4.99e-05	4	101	2	19376779
Pubmed	Coordinated regulation of cardiac Na(+)/Ca (2+) exchanger and Na (+)-K (+)-ATPase by phospholemman (FXYD1).	SLC8A1 ATP1A1	4.99e-05	4	101	2	23224879
Pubmed	Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice.	ATP1A1 ATP1A3	4.99e-05	4	101	2	17234593
Pubmed	Biology, structure and mechanism of P-type ATPases.	ATP1A1 ATP1A3 ATP1A4	8.22e-05	29	101	3	15071553
Pubmed	BCR binds to the xeroderma pigmentosum group B protein.	MCF2 GTF2H1	8.30e-05	5	101	2	10403766
Pubmed	Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex.	PKD2 ATP1A1	8.30e-05	5	101	2	11901144
Pubmed	Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain.	SLC8A1 ATP1A1	8.30e-05	5	101	2	16292983
Pubmed	MVH in piRNA processing and gene silencing of retrotransposons.	TDRD9 TDRD1	8.30e-05	5	101	2	20439430
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	SLC12A4 TIAM1 ATP1A1 UTRN EPHA3 AGAP1 AGAP3	1.19e-04	377	101	7	38117590
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TM9SF4 NWD2 NRXN1 RAPGEF2	1.24e-04	87	101	4	12465718
Pubmed	Green fluorescence protein driven by the Na,K-ATPase α4 isoform promoter is expressed only in male germ cells of mouse testis.	ATP1A1 ATP1A4	1.24e-04	6	101	2	23229519
Pubmed	Transport and pharmacological properties of nine different human Na, K-ATPase isozymes.	ATP1A1 ATP1A3	1.24e-04	6	101	2	10636900
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	SFMBT1 RAPGEF6 ITGB7 IGSF10 SNED1	1.35e-04	168	101	5	30631154
Pubmed	A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.	FAT3 CDH4 SDK1 EPHA3	1.47e-04	91	101	4	28558017
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	DCHS2 FAT3	1.74e-04	7	101	2	16059920
Pubmed	Expression and distribution of Na, K-ATPase isoforms in the human uterus.	ATP1A1 ATP1A3	1.74e-04	7	101	2	20065300
Pubmed	Mouse GTSF1 is an essential factor for secondary piRNA biogenesis.	TDRD9 TDRD1	1.74e-04	7	101	2	29437694
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	SLC8A1 NRXN1 ATP1A1 ATP1A3 CD200 AGAP1 AGAP3	1.85e-04	405	101	7	38187761
Pubmed	The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements.	TDRD9 TDRD1	2.31e-04	8	101	2	22020280
Pubmed	Genes encoding alpha and beta subunits of Na,K-ATPase are located on three different chromosomes in the mouse.	ATP1A1 ATP1A3	2.31e-04	8	101	2	2885848
Pubmed	Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.	CACNA1I CACNA1H	2.31e-04	8	101	2	28330839
Pubmed	Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord.	CACNA1I CACNA1H	2.31e-04	8	101	2	34478646
Pubmed	Enhanced inhibitory neurotransmission in the cerebellar cortex of Atp1a3-deficient heterozygous mice.	ATP1A1 ATP1A3	2.31e-04	8	101	2	23652595
Pubmed	Intracellular calcium plays an essential role in cardiac development.	CACNA1I CACNA1H	2.31e-04	8	101	2	12761855
Pubmed	GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.	AGAP1 AGAP3	2.97e-04	9	101	2	12640130
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1I CACNA1H	2.97e-04	9	101	2	16382099
Pubmed	Localization of the 5' end of the MCF2 oncogene to human chromosome 15q15----q23.	MCF2 ROS1	2.97e-04	9	101	2	1611909
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	TM9SF4 ARAP3 TIAM1 ATP1A1 CAPRIN1	3.17e-04	202	101	5	33005030
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DCHS2 CUL9 INTS8 TXNDC11 TIAM1 MEGF9 RAPGEF2 UTRN CAPRIN1 SCAI AGAP1 AGAP3	3.54e-04	1285	101	12	35914814
Pubmed	Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members.	TDRD9 TDRD1	3.70e-04	10	101	2	19584108
Pubmed	Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage.	CACNA1I CACNA1H	3.70e-04	10	101	2	24778262
Pubmed	JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function.	RAPGEF6 RAPGEF2	3.70e-04	10	101	2	23885123
Pubmed	A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.	COPB2 SVIL ATP1A1 UTRN	3.99e-04	118	101	4	27377895
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	CUL9 RGS13 KCNH1 SDK1 AGAP3	4.13e-04	214	101	5	22199357
Pubmed	AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.	AGAP1 AGAP3	4.51e-04	11	101	2	15381706
Pubmed	Deciphering epiblast lumenogenesis reveals proamniotic cavity control of embryo growth and patterning.	LAMA1 ATP1A1	4.51e-04	11	101	2	33692105
Pubmed	Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays.	MTFP1 CASTOR1	4.51e-04	11	101	2	15998911
Pubmed	Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus.	ATP1A1 ATP1A4	4.51e-04	11	101	2	28746879
Pubmed	Loss of ciliary transition zone protein TMEM107 leads to heterotaxy in mice.	TMEM107 PKD2	5.41e-04	12	101	2	31887266
Pubmed	Retinal pigment epithelial integrity is compromised in the developing albino mouse retina.	ATP1A1 ATP1A3	5.41e-04	12	101	2	27097562
Pubmed	Cytoplasmic compartmentalization of the fetal piRNA pathway in mice.	TDRD9 TDRD1	5.41e-04	12	101	2	20011505
Pubmed	RhoG signals in parallel with Rac1 and Cdc42.	MCF2 TIAM1	6.38e-04	13	101	2	12376551
Pubmed	Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome.	TIAM1 ROS1	6.38e-04	13	101	2	8812055
GeneFamily	ATPase Na+/K+ transporting subunits	ATP1A1 ATP1A3 ATP1A4	1.92e-06	7	70	3	1208
GeneFamily	Fibronectin type III domain containing	SNED1 FNDC7 TNN ROS1 SDK1 EPHA3	3.59e-05	160	70	6	555
GeneFamily	ArfGAPs	ARAP3 AGAP1 AGAP3	2.79e-04	33	70	3	395
GeneFamily	Integrator complex	INTS8 INTS4	1.50e-03	15	70	2	1366
GeneFamily	Dyneins, axonemal	DNAH3 DNAH7	1.94e-03	17	70	2	536
GeneFamily	Cadherin related	DCHS2 FAT3	1.94e-03	17	70	2	24
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP1 AGAP3	1.94e-03	17	70	2	1291
GeneFamily	Calcium voltage-gated channel subunits	CACNA1I CACNA1H	4.52e-03	26	70	2	253
GeneFamily	Sterile alpha motif domain containing	SFMBT1 ARAP3 EPHA3	4.82e-03	88	70	3	760
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	BMP6 SVIL ADGRF5 ROS1 ATP1A1 ATL2 SDK1 AGAP1	7.97e-09	181	100	8	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT3 DNAH7 SNED1 NWD2 LRRIQ1 KCNH1 ADGRF5 EPHA3	8.32e-09	182	100	8	14a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 TSPAN19 DNAH7 LRRIQ1 NRXN1 SLC22A4 SDK1	1.64e-07	179	100	7	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 IGSF10 SNED1 NWD2 ELANE SDK1 HACD1	1.77e-07	181	100	7	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 LAMA1 SLC8A1 NRXN1 ROS1 ATP1A4 SDK1	1.98e-07	184	100	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 LAMA1 SLC8A1 NRXN1 ROS1 ATP1A4 SDK1	1.98e-07	184	100	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 LAMA1 SLC8A1 NRXN1 ROS1 ATP1A4 SDK1	1.98e-07	184	100	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A2 BMP6 ARAP3 ADGRF5 ATP1A1 EMP1 SEC14L1	2.84e-07	194	100	7	f159ef8541d75a4e98468947f231bb463bec922c
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH3 TSPAN19 DNAH7 LRRIQ1 ADGRF5 SDK1 AGAP1	2.94e-07	195	100	7	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH3 TSPAN19 DNAH7 LRRIQ1 ADGRF5 SDK1 AGAP1	2.94e-07	195	100	7	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	DNAH3 TSPAN19 DNAH7 LRRIQ1 ADGRF5 SDK1 AGAP1	3.04e-07	196	100	7	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	DNAH3 TSPAN19 DNAH7 LRRIQ1 ADGRF5 SDK1 AGAP1	3.04e-07	196	100	7	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DNAH3 TDRD9 TSPAN19 PDCL2 GLB1L2 DNAH7 LRRIQ1	3.48e-07	200	100	7	96701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FAT3 CSMD2 SLC8A1 CACNA1I CACNA1H AGAP3	1.02e-06	147	100	6	8f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DCHS2 TDRD9 DNAH7 ITIH3 C12orf54 SVIL	1.14e-06	150	100	6	909ccab92855f5f049dc29593aadab1ea973297b
ToppCell	TCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue\|TCGA-Thryoid / Sample_Type by Project: Shred V9	TSPAN19 DNAH7 IGSF10 LRRIQ1 NRXN1 EPHA3	1.55e-06	158	100	6	8e48952af0831a1fc71ad422e8216b5a92a75991
ToppCell	TCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue\|TCGA-Thryoid / Sample_Type by Project: Shred V9	TSPAN19 DNAH7 IGSF10 LRRIQ1 NRXN1 EPHA3	1.55e-06	158	100	6	e5b55c15a8c99c8d7fc94949f0d3c22e0c3fee7b
ToppCell	TCGA-Thryoid-Solid_Tissue_Normal\|TCGA-Thryoid / Sample_Type by Project: Shred V9	TSPAN19 DNAH7 IGSF10 LRRIQ1 NRXN1 EPHA3	1.55e-06	158	100	6	55214d674808584e4d48f8c5e3b8c0e206cb9bb8
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	DNAH3 FAT3 CSMD2 NRXN1 CDH4 EPHA3	1.61e-06	159	100	6	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	Sigmoid-Macrophage-Macrophage\|Macrophage / Region, Cell class and subclass	TMEM176B ITGB7 GPR160 SLC8A1 UTRN SEC14L1	2.21e-06	168	100	6	bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCell	Mild-Treg\|World / Disease group and Cell class	SERPINE3 CUL9 RGS13 ASB16 ATP1A4 HACD1	2.37e-06	170	100	6	f3f177534badca34e1ae8671b7f583ee6688e14b
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT3 DNAH7 NWD2 LRRIQ1 KCNH1 ADGRF5	3.09e-06	178	100	6	0e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCell	Mild-Treg\|Mild / Disease group and Cell class	CUL9 DNPH1 RGS13 ASB16 ATP1A4 HACD1	3.09e-06	178	100	6	e669fd95278e145f55126d0e6be8fb2d6184dbbd
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 IGSF10 SNED1 NWD2 TIAM1 SDK1	3.29e-06	180	100	6	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 IGSF10 SNED1 NWD2 TIAM1 SDK1	3.29e-06	180	100	6	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 BMP6 ARAP3 TIAM1 ADGRF5 ATP1A4	3.51e-06	182	100	6	b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCell	(1)_T_cells-(1)_T_regulatory\|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	CUL9 DNPH1 TIAM1 HACD1 CD200 SEC14L1	3.74e-06	184	100	6	3cbf81757653652441843d85cb7ec1dcf25ca1b0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BMP6 ARAP3 ADGRF5 EMP1 UTRN SEC14L1	4.49e-06	190	100	6	bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	BMP6 ARAP3 ADGRF5 EMP1 UTRN SEC14L1	4.49e-06	190	100	6	1519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCell	facs-GAT-Fat-3m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 SLC8A1 SVIL ATP1A1 CAPRIN1 SEC14L1	4.49e-06	190	100	6	1d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 IGSF10 SNED1 NWD2 SDK1 EPHA3	4.63e-06	191	100	6	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 ARAP3 ADGRF5 UTRN EPHA3 SEC14L1	4.92e-06	193	100	6	2e72309607902dabe3218888b22a77fe941f3570
ToppCell	ASK440-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH3 TSPAN19 TMEM107 DNAH7 LRRIQ1 SLC22A4	5.06e-06	194	100	6	c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	DNAH3 TSPAN19 DNAH7 LRRIQ1 SDK1 AGAP1	5.22e-06	195	100	6	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH3 TSPAN19 TMEM107 DNAH7 LRRIQ1 SLC22A4	5.22e-06	195	100	6	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH3 TSPAN19 PDCL2 GLB1L2 DNAH7 LRRIQ1	5.22e-06	195	100	6	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	facs-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNED1 BMP6 ARAP3 ADGRF5 EMP1 UTRN	5.22e-06	195	100	6	7f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 ARAP3 ADGRF5 EMP1 UTRN EPHA3	5.22e-06	195	100	6	77e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	BMP6 ARAP3 ADGRF5 EMP1 CD200 SEC14L1	5.37e-06	196	100	6	7cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 BMP6 ARAP3 ADGRF5 UTRN SEC14L1	5.69e-06	198	100	6	451003a21162eeae90739fdb502bb50b362d80c8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 BMP6 ARAP3 ADGRF5 UTRN SEC14L1	5.69e-06	198	100	6	440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 ARAP3 ADGRF5 EMP1 UTRN SEC14L1	5.69e-06	198	100	6	0a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DNAH3 MMS22L TSPAN19 DNAH7 LRRIQ1 SLC22A4	5.86e-06	199	100	6	15f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	LAMA1 BMP6 ASB16 EMP1 SDK1	1.30e-05	134	100	5	d29ac8152dc581c0da2430d06cd259ac0eded808
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	LAMA1 BMP6 ASB16 EMP1 SDK1	1.30e-05	134	100	5	459c39df15d3cf9144ce7827e8d14830d31353bb
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	LAMA1 BMP6 ASB16 EMP1 SDK1	1.30e-05	134	100	5	d065449ca3679e4818b74fb7302cc7f1ce62f691
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	LAMA1 BMP6 ASB16 EMP1 SDK1	1.30e-05	134	100	5	0be389f416818a22e80098dd809fdf45b14171e8
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GLB1L2 TIAM1 SVIL EMP1 EPHA3	1.91e-05	145	100	5	590ba937c741ae67460f303eca88b1cd3ac87f64
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 LAMA1 DNAH7 IGSF10 BMP6	2.04e-05	147	100	5	f5109e0f4e8b46a977a763c9c72a2df9840e3977
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 LAMA1 DNAH7 IGSF10 BMP6	2.04e-05	147	100	5	ad0c575bc9c5f201f2a7810452e8b3f741e65d89
ToppCell	TCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue-3\|TCGA-Thryoid / Sample_Type by Project: Shred V9	TSPAN19 DNAH7 IGSF10 LRRIQ1 EPHA3	2.55e-05	154	100	5	4e9203c220a44c70cd7979796a0b461991422257
ToppCell	Control-Epithelial_airway-Ciliated_cells-Ciliated\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 TSPAN19 PDCL2 DNAH7 LRRIQ1	2.55e-05	154	100	5	4e3bc24043144143842627cacf6f90dda2228910
ToppCell	Control-Epithelial_airway-Ciliated_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 TSPAN19 PDCL2 DNAH7 LRRIQ1	2.55e-05	154	100	5	7556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 TSPAN19 GLB1L2 DNAH7 LRRIQ1	2.63e-05	155	100	5	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 TSPAN19 GLB1L2 DNAH7 LRRIQ1	2.63e-05	155	100	5	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRROS ITGB7 SLC22A4 ELANE ATP1A3	3.55e-05	165	100	5	ba68090d79e2243af2bdee0c27a32e65f540f8ac
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 TSPAN19 TDRD1 DNAH7 LRRIQ1	3.98e-05	169	100	5	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 TSPAN19 DNAH7 LRRIQ1 SLC22A4	4.45e-05	173	100	5	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SNED1 NWD2 LRRIQ1 KCNH1 ADGRF5	4.57e-05	174	100	5	9cc7251661ea2b1565eef1dfb8cf6dec3ade13d4
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GLB1L2 TIAM1 SVIL CACNA1H SDK1	4.82e-05	176	100	5	05ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 TSPAN19 DNAH7 LRRIQ1 GALNT8	5.09e-05	178	100	5	3b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTFP1 BMP6 SLC8A1 TIAM1 CD200	5.23e-05	179	100	5	7c8a2fa1326c73dc9e774df645b572864fd97133
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSPAN19 GLB1L2 DNAH7 LRRIQ1 SLC22A4	5.37e-05	180	100	5	92fb01b91261b3103454924cde56add337b41844
ToppCell	droplet-Liver-Npc-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP6 ARAP3 TIAM1 ADGRF5 ATP1A4	5.66e-05	182	100	5	dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TXNDC11 BMP6 SLC12A4 RAPGEF2 SEC14L1	5.66e-05	182	100	5	626aabfd9ac662c1d189f7c4b660482914d9e669
ToppCell	368C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DNAH3 TSPAN19 DNAH7 LRRIQ1 SLC22A4	5.66e-05	182	100	5	975f6275777fc578eba528e50f69891c66ec44ad
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TXNDC11 BMP6 SLC12A4 RAPGEF2 SEC14L1	5.66e-05	182	100	5	a00abff41c12b71d5860c494b8c722d649fd5f36
ToppCell	368C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DNAH3 TSPAN19 DNAH7 LRRIQ1 SLC22A4	5.66e-05	182	100	5	f8c28fa76751062c4cfba0db8af1b377f947f739
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP6 ARAP3 TIAM1 ADGRF5 ATP1A4	5.66e-05	182	100	5	010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CUL9 ATP13A2 GALNT8 CACNA1H SDK1	6.11e-05	185	100	5	d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCell	LA-07._Pericyte\|LA / Chamber and Cluster_Paper	ADGRF5 CACNA1H RAPGEF2 UTRN EPHA3	6.11e-05	185	100	5	ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCell	Control-Endothelial_cells-Endothelial_cells_(other)\|Control / group, cell type (main and fine annotations)	BMP6 ARAP3 ADGRF5 EMP1 SEC14L1	6.27e-05	186	100	5	c6075fe84226b370c5139066793844ad33ae2db1
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CSMD2 ITIH3 SLC8A1 SDK1 HACD1	6.27e-05	186	100	5	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT3 NWD2 KCNH1 SCAI EPHA3	6.43e-05	187	100	5	f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 BMP6 ARAP3 ADGRF5 SEC14L1	6.43e-05	187	100	5	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	BMP6 ADGRF5 RAPGEF2 UTRN SEC14L1	6.43e-05	187	100	5	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 TSPAN19 DNAH7 LRRIQ1 SLC22A4	6.43e-05	187	100	5	e61992de4f98eeea08b43213850769d923f8db48
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	FAT3 SLC8A1 SVIL PKD2 SDK1	6.59e-05	188	100	5	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT3 NWD2 KCNH1 RAPGEF2 EPHA3	6.59e-05	188	100	5	50c1b1d690f0e9443082f2adf4f1b8e9ce4cd337
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 FAT3 TSPAN19 DNAH7 LRRIQ1	6.76e-05	189	100	5	cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCell	P07-Endothelial-unknown_endothelial_cell-endothelial_unknown_1\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NRROS ATP13A2 ADGRF5 EMP1 CD200	6.76e-05	189	100	5	fcfb28bd96471affc13e55aa7228f594aaa967cd
ToppCell	P07-Endothelial-unknown_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NRROS ATP13A2 ADGRF5 EMP1 CD200	6.76e-05	189	100	5	f515a04ae1746257d4568cea13a3dd75b4b05275
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT3 SLC8A1 NWD2 KCNH1 SCAI	6.93e-05	190	100	5	d594da827e3c16644952b9589cc12b947ce36279
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH3 TSPAN19 DNAH7 LRRIQ1 SLC22A4	6.93e-05	190	100	5	a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	FAT3 IGSF10 SLC8A1 ATP1A1 ATP1A3	6.93e-05	190	100	5	6e92c78799f34b31d098854503c796edb0dc7f80
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ADGRF5 CACNA1H RAPGEF2 UTRN SEC14L1	6.93e-05	190	100	5	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CSMD2 ITIH3 CACNA1H SDK1 HACD1	6.93e-05	190	100	5	73d94fbae92029745989a8712eed8b99fd84c193
ToppCell	Control-Stromal-SMC\|Stromal / Disease state, Lineage and Cell class	ITIH3 SLC8A1 ADGRF5 CACNA1H HACD1	7.11e-05	191	100	5	2da83c493e60ad0278848957645277d76737a188
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARAP3 EMP1 UTRN EPHA3 SEC14L1	7.28e-05	192	100	5	bacbaef1f230051335f4433e55db07a161b96b4c
ToppCell	facs-BAT-Fat-18m-Endothelial\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR160 BMP6 ARAP3 ADGRF5 CD200	7.28e-05	192	100	5	3a99c521c599a289ee2309d97be5ceb99f8aa220
ToppCell	Nasal_Brush-Immune-Neutrophils\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	TMEM176B NRROS SLC8A1 CD33 ELANE	7.28e-05	192	100	5	20a7f7beb01df1c4f915ec2f9b5a9dbcab157187
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADGRF5 EMP1 UTRN CD200 SEC14L1	7.28e-05	192	100	5	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH3 TSPAN19 DNAH7 LRRIQ1 SLC22A4	7.28e-05	192	100	5	be592e661367affced9ebe80849b466e6adb3a34
ToppCell	facs-BAT-Fat-18m-Endothelial-endothelial_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR160 BMP6 ARAP3 ADGRF5 CD200	7.28e-05	192	100	5	f9777e0fdd86c2a514f05a42502888329a94b396
ToppCell	facs-BAT-Fat-18m-Endothelial-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR160 BMP6 ARAP3 ADGRF5 CD200	7.28e-05	192	100	5	562e15876088af9189744c9b2de5c4863d7f15fd
ToppCell	RA-09._Endothelium_I\|RA / Chamber and Cluster_Paper	BMP6 ARAP3 ADGRF5 UTRN SEC14L1	7.28e-05	192	100	5	8a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SLC8A1 SVIL RAPGEF2 SDK1 AGAP1	7.28e-05	192	100	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 TSPAN19 DNAH7 LRRIQ1 SLC22A4	7.46e-05	193	100	5	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	facs-Aorta-Heart-18m-Endothelial-aortic_endothelial_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR160 BMP6 ADGRF5 UTRN CD200	7.46e-05	193	100	5	7b7fecd332d3c99b8810bd7e14ab33aab46f2ffd
ToppCell	facs-Aorta-Heart-18m-Endothelial\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR160 BMP6 ADGRF5 UTRN CD200	7.46e-05	193	100	5	7170cbaef0ba1b65cab89c5d4ce525e6c04e4418
Disease	familial hemiplegic migraine (implicated_via_orthology)	ATP1A1 ATP1A3 ATP1A4	1.19e-06	7	97	3	DOID:0060178 (implicated_via_orthology)
Disease	nervous system disease (implicated_via_orthology)	ATP1A1 ATP1A3 ATP1A4	7.42e-06	12	97	3	DOID:863 (implicated_via_orthology)
Disease	household income	MMS22L ARAP3 CACNA1I EMP1 RAPGEF2 CDH4 AGAP1	6.69e-05	304	97	7	EFO_0009695
Disease	thalamus volume	FAT3 EPHA3 AGAP1 OR2A2	1.81e-04	85	97	4	EFO_0006935
Disease	neuroimaging measurement	DCHS2 FAT3 PDCL2 ATP13A2 BMP6 LRRIQ1 CASTOR1 RAPGEF2 SCAI EPHA3 AGAP1 AGAP3	2.02e-04	1069	97	12	EFO_0004346
Disease	epilepsy (implicated_via_orthology)	SLC12A4 KCNH1 ATP1A1 ATP1A3 ATP1A4	2.07e-04	163	97	5	DOID:1826 (implicated_via_orthology)
Disease	cups of coffee per day measurement	ATP1A1 ATP1A3 ATP1A4	3.11e-04	40	97	3	EFO_0006782
Disease	3-phenylpropionate hydrocinnamate measurement	LAMA1 AGAP1	4.73e-04	10	97	2	EFO_0021010
Disease	abdominal adipose tissue measurement	ATP1A1 ATP1A3 ATP1A4	7.16e-04	53	97	3	EFO_0803316
Disease	venous thromboembolism, fibrinogen measurement	DCHS2 RAPGEF6 PARP10	1.42e-03	67	97	3	EFO_0004286, EFO_0004623
Disease	neuroimaging measurement, brain volume measurement	FAT3 ATP13A2 KBTBD4 SCAI EPHA3	2.58e-03	286	97	5	EFO_0004346, EFO_0006930
Disease	obsolete Mendelian syndromes with cleft lip/palate	BMP6 SVIL	2.59e-03	23	97	2	MONDO_0015335
Disease	response to venlafaxine	CSMD2 AGAP1	3.05e-03	25	97	2	EFO_0006328

Protein segments in the cluster

Peptide	Gene	Start	Entry
TWVELGVDQTVDVVV	TDRD1	706	Q9BXT4
QVTLSFQDWLASVTE	C2orf42	356	Q9NWW7
ISIEDSFVNSQEWTL	AGAP3	71	Q96P47
IAIEDAFVNSQEWTL	AGAP1	51	Q9UPQ3
LDTSVWSNEIVQLFI	ARAP3	546	Q8WWN8
IQVVSFVTEQNWDSL	CSMD2	1836	Q7Z408
LEWLQQADVVVAEVT	DNPH1	81	O43598
SEFLQVAEATWLVLN	CASTOR1	66	Q8WTX7
VWNHETQTLVKTFEV	COPB2	41	P35606
IVETVSNQLAWSAEQ	ASB16	86	Q96NS5
WTVETVEVVNSLQQQ	CAPRIN1	316	Q14444
VTVHESIEQLFWSLE	NWD2	636	Q9ULI1
EQVRSAAVQLIWVVS	INTS4	246	Q96HW7
DLWEVVVQICSVSSQ	INTS8	716	Q75QN2
VSTIANVWLVSNTVD	EMP1	21	P54849
TLEIFGIQWVTETAL	MMS22L	71	Q6ZRQ5
VTQITQSVINVSWTI	FNDC7	551	Q5VTL7
FWLQVQESVTVQEGL	CD33	21	P20138
AFFVSIVVVQWADLV	ATP1A1	921	P05023
VNEVTNAEEDVWVII	PDCL2	101	Q8N4E4
NNVAWLVVDSIVDVI	KCNH1	246	O95259
ADVSWTQFNIIILTV	MEGF9	506	Q9H1U4
RVTVAVVDTFVWQAL	MTFP1	76	Q9UDX5
VVDTFVWQALASVAI	MTFP1	81	Q9UDX5
TTLFIDQVEAKWVEV	NRXN1	126	Q9ULB1
IISDSNSVFIDWVLE	PHOSPHO2	96	Q8TCD6
PWDTLQQVTTVTFQD	LRRIQ1	791	Q96JM4
VRINQTVTFWVSLQA	ITGB7	431	P26010
TWVNQVVIFATCVFV	OR2A2	191	Q6IF42
DTWLNQVVIFAASVF	OR2A5	191	Q96R48
LQNSTITFWNITLED	CD200	101	P41217
QNVSTTVIVRVWDEN	DCHS2	1171	Q6V1P9
AFITCWEEVTTLVQA	GPR160	196	Q9UJ42
VDTNWAVTVITTFVT	OR6S1	271	Q8NH40
EDSSWQLFTVQVQTE	ATP13A2	96	Q9NQ11
TVTWILANQTVVSES	IGSF10	1776	Q6WRI0
VICVSSIFWTQEVSQ	DNAH3	1286	Q8TD57
QVVFGNVLVWSELIT	EBF4	286	Q9BQW3
DVDVNQIINTISEWI	EPM2AIP1	291	Q7L775
VLVLQTCSTQVWEIQ	GALNT8	611	Q9NY28
IVTVFQILTQEDWNV	CACNA1I	811	Q9P0X4
ESVVLFLVAWTVTEI	HACD1	166	B0YJ81
QTVLCVSQIFWTKEV	DNAH7	1181	Q8WXX0
STIWVVVQVLDENDN	FAT3	1236	Q8TDW7
ETTGIQVWNEVFVID	ATL2	146	Q8NHH9
GTVIDQIAETLWEQV	ATL2	531	Q8NHH9
LEFDITATSNLWVVT	BMP6	306	P22004
LQVPSEQVAFTVTAW	CDH4	91	P55283
LVVNAVSSSQIWLET	CCHCR1	431	Q8TD31
NVISNINETSVILDW	EPHA3	331	P29320
EAIASVQAEANTVWT	MCF2	866	P10911
AFFVSIVVVQWADLI	ATP1A3	911	P13637
WLSVVQEQVSRFLAA	CUL9	1476	Q8IWT3
AQFVNWIDSIIQRSE	ELANE	236	P08246
WLSSGINQVIVFEET	GLB1L2	601	Q8IW92
LWAIVTVFQILTQED	CACNA1H	961	O95180
TVFQILTQEDWNVVL	CACNA1H	966	O95180
QIVDASSVITWDFDV	SEC14L1	541	Q92503
VQTEAVNSTTIQFLW	SDK1	876	Q7Z5N4
QDVYLSTVVTEWNLV	SLC22A4	121	Q9H015
VDGNVTNITTVSLWE	NRROS	306	Q86YC3
TVASFQQWQVAERVL	PARP10	216	Q53GL7
SNLTLEEVLQWAQSF	RGS13	21	O14921
VLTWLLSAEDTFQEQ	UTRN	321	P46939
WNNFSTEINTTSVLV	ERVW-1	206	Q9UQF0
IVNQETFWVASEILT	RAPGEF6	906	Q8TEU7
TFWVASEILTEANQL	RAPGEF6	911	Q8TEU7
QFEITSVSVDVWHIL	SVIL	1746	O95425
WIVFAIAVTNRTVDL	TMEM150B	21	A6NC51
TAEAWAIFQEQTVVL	TMEM191B	206	P0C7N4
QTAEAWAIFQEQTVV	TMEM191C	206	A6NGB0
TIEQINDWFTIGKTV	TDRD9	6	Q8NDG6
QRTWVAVVEEETSFL	MTCP1	26	P56278
DFQVEVTTEKITLWN	ITIH3	721	Q06033
NVWTETTQLEVAVSG	KBTBD4	356	Q9NVX7
WVTITLDLRQVFQVA	LAMA1	106	P25391
SEEIQQQIWIPSVFI	RNF167	126	Q9H6Y7
FTNLTWDQVITLDQV	TENT5D	6	Q8NEK8
ALVFSTWQDVLDIIS	SHPRH	1531	Q149N8
DIDSAIEVFTQAIQW	SRP72	421	O76094
TAVVDNETVATQLWS	SLC12A4	326	Q9UP95
AAVVLCVNSFIWQTE	TMEM176B	141	Q3YBM2
FEVTNVTASTISVQW	SNED1	1011	Q8TER0
LLVANTWFIVVAAIQ	ADGRF5	1061	Q8IZF2
TAFFVTIVVVQWADL	ATP1A4	926	Q13733
VTITETLWDQVLTVF	C12orf54	36	Q6X4T0
EEVINQETFWVASEI	RAPGEF2	761	Q9Y4G8
LVVSQVISAEEFWAN	GTF2H1	131	P32780
VNFTQEEWTLLDISQ	ZNF700	31	Q9H0M5
VQIHWFSIINSVVVV	TM9SF4	276	Q92544
LFQTTSQTELENWIT	TIAM1	526	Q13009
LETVSQIISGWVADQ	SLC16A4	346	O15374
QNLVTDWVTENTATV	TNN	801	Q9UQP3
WEVFNESLLTEINIT	STX19	191	Q8N4C7
VVITLFWSRDSNIQA	TMEM107	21	Q6UX40
QVEWNLVLQEVAAFI	SCAI	221	Q8N9R8
WEQVSAAFAQLVLVS	SERPINE3	176	A8MV23
QNQVVWTFSAERVIS	ROS1	1171	P08922
FWNCLDVVIVVLSVV	PKD2	506	Q13563
TTDTFWEVVLQKQDV	TXNDC11	696	Q6PKC3
VIVSTVLIEQFGWFI	SLC30A5	606	Q8TAD4
QAFQDSLSTWIVTVV	SFMBT1	171	Q9UHJ3
AILVSSDLFESWNIQ	VN1R17P	66	Q8TDU5
VLITWTFAVQVVLSA	TSPAN19	91	P0C672
TNSWREQFIEAITVS	SLC8A1	741	P32418