Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	IQCA1L APPBP2 ABCA1 MYH9 CENPE MYO9B ATP6V1E2 MYO18A MACF1 CHD1 ATP2B2 ATP2B3 RAD50	3.63e-06	614	90	13	GO:0140657
GeneOntologyMolecularFunction	ADP binding	MYH9 MYO9B MYO18A GCK	6.45e-05	48	90	4	GO:0043531
GeneOntologyMolecularFunction	ATP hydrolysis activity	IQCA1L ABCA1 MYO9B MYO18A MACF1 CHD1 ATP2B2 ATP2B3 RAD50	1.67e-04	441	90	9	GO:0016887
GeneOntologyMolecularFunction	cytoskeletal motor activity	APPBP2 MYH9 CENPE MYO9B MYO18A	1.95e-04	118	90	5	GO:0003774
GeneOntologyMolecularFunction	glucokinase activity	HKDC1 GCK	1.99e-04	5	90	2	GO:0004340
GeneOntologyMolecularFunction	hexokinase activity	HKDC1 GCK	1.99e-04	5	90	2	GO:0004396
GeneOntologyMolecularFunction	fructokinase activity	HKDC1 GCK	1.99e-04	5	90	2	GO:0008865
GeneOntologyMolecularFunction	cytoskeletal protein binding	ROCK2 BICD2 APPBP2 MYH9 CTTNBP2 MTUS1 CENPE MYO9B SYNE1 SCN5A GAS8 MYO18A MACF1 STMN1	3.87e-04	1099	90	14	GO:0008092
GeneOntologyMolecularFunction	small GTPase binding	ROCK2 BICD2 ABCA1 ANKFY1 MYO9B GAS8 RILPL1	6.21e-04	321	90	7	GO:0031267
GeneOntologyMolecularFunction	P-type calcium transporter activity	ATP2B2 ATP2B3	1.08e-03	11	90	2	GO:0005388
GeneOntologyMolecularFunction	GTPase binding	ROCK2 BICD2 ABCA1 ANKFY1 MYO9B GAS8 RILPL1	1.21e-03	360	90	7	GO:0051020
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA1 ATP6V1E2 ATP2B2 ATP2B3	1.50e-03	109	90	4	GO:0042626
GeneOntologyMolecularFunction	D-glucose binding	HKDC1 GCK	1.76e-03	14	90	2	GO:0005536
GeneOntologyBiologicalProcess	cell cycle checkpoint signaling	CUL4A TAOK3 CENPE UFL1 PARP9 CDC5L RAD50 CEP63	4.12e-06	217	88	8	GO:0000075
GeneOntologyBiologicalProcess	DNA damage checkpoint signaling	CUL4A TAOK3 UFL1 PARP9 CDC5L CEP63	2.56e-05	136	88	6	GO:0000077
GeneOntologyBiologicalProcess	DNA integrity checkpoint signaling	CUL4A TAOK3 UFL1 PARP9 CDC5L CEP63	3.67e-05	145	88	6	GO:0031570
GeneOntologyBiologicalProcess	endosomal vesicle fusion	ANKFY1 VPS8 RUFY1	4.04e-05	16	88	3	GO:0034058
GeneOntologyBiologicalProcess	negative regulation of cell cycle phase transition	CUL4A TAOK3 CENPE UFL1 PARP9 CDC5L RAD50 CEP63	5.52e-05	311	88	8	GO:1901988
GeneOntologyBiologicalProcess	DNA repair	CUL4A SMG1 TAOK3 TADA2B SYCP1 GINS2 UFL1 PARP9 CDC5L CEP164 RAD50	9.64e-05	648	88	11	GO:0006281
GeneOntologyBiologicalProcess	negative regulation of cell cycle process	CUL4A TAOK3 CENPE UFL1 PARP9 CDC5L RAD50 CEP63	1.58e-04	362	88	8	GO:0010948
GeneOntologyBiologicalProcess	DNA metabolic process	CUL4A ORC2 SMG1 TAOK3 TADA2B SYCP1 MYO18A GINS2 UFL1 PARP9 CDC5L CEP164 RAD50 CEP63	1.85e-04	1081	88	14	GO:0006259
GeneOntologyCellularComponent	microtubule organizing center	ROCK2 BICD2 ORC2 MTUS1 GAS8 CCDC18 MYO18A CCDC178 POC5 RILPL1 TSKS CEP164 CEP63	1.06e-04	919	87	13	GO:0005815
GeneOntologyCellularComponent	supramolecular fiber	KRT23 APPBP2 MYH9 MTUS1 CENPE MYO9B SYNE1 SCN5A GAS8 MYO18A MACF1 POLR2M STMN1 GCK	3.47e-04	1179	87	14	GO:0099512
GeneOntologyCellularComponent	basal cortex	PHLDB1 GCK	3.55e-04	7	87	2	GO:0045180
GeneOntologyCellularComponent	supramolecular polymer	KRT23 APPBP2 MYH9 MTUS1 CENPE MYO9B SYNE1 SCN5A GAS8 MYO18A MACF1 POLR2M STMN1 GCK	3.71e-04	1187	87	14	GO:0099081
GeneOntologyCellularComponent	nuclear protein-containing complex	BICD2 ORC2 MYH9 SUPT5H SYNE1 HNRNPM NUP88 AGFG1 AFF1 GINS2 POLR2M MPHOSPH6 CDC5L GATAD2B RAD50	5.20e-04	1377	87	15	GO:0140513
GeneOntologyCellularComponent	nuclear chromosome	ORC2 SYCP1 GINS2 CHD1 CDC5L RAD50	6.74e-04	254	87	6	GO:0000228
GeneOntologyCellularComponent	centriole	POC5 RILPL1 TSKS CEP164 CEP63	7.63e-04	172	87	5	GO:0005814
GeneOntologyCellularComponent	cell cortex	PHLDB1 MYH9 CTTNBP2 MYO9B MACF1 POLR2M GCK	9.07e-04	371	87	7	GO:0005938
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B3	1.25e-04	4	86	2	IPR022141
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B3	1.25e-04	4	86	2	PF12424
Domain	P-type_ATPase_IIB	ATP2B2 ATP2B3	1.25e-04	4	86	2	IPR006408
Domain	Hexokinase_C	HKDC1 GCK	2.08e-04	5	86	2	IPR022673
Domain	Hexokinase_N	HKDC1 GCK	2.08e-04	5	86	2	IPR022672
Domain	Hexokinase_1	HKDC1 GCK	2.08e-04	5	86	2	PF00349
Domain	Hexokinase_2	HKDC1 GCK	2.08e-04	5	86	2	PF03727
Domain	HEXOKINASE_2	HKDC1 GCK	2.08e-04	5	86	2	PS51748
Domain	Hexokinase_BS	HKDC1 GCK	2.08e-04	5	86	2	IPR019807
Domain	HEXOKINASE_1	HKDC1 GCK	2.08e-04	5	86	2	PS00378
Domain	Hexokinase	HKDC1 GCK	3.11e-04	6	86	2	IPR001312
Domain	IQ	MYH9 MYO9B SCN5A MYO18A	5.32e-04	81	86	4	SM00015
Domain	Myosin_head_motor_dom	MYH9 MYO9B MYO18A	7.08e-04	38	86	3	IPR001609
Domain	MYOSIN_MOTOR	MYH9 MYO9B MYO18A	7.08e-04	38	86	3	PS51456
Domain	Myosin_head	MYH9 MYO9B MYO18A	7.08e-04	38	86	3	PF00063
Domain	MYSc	MYH9 MYO9B MYO18A	7.08e-04	38	86	3	SM00242
Domain	IQ_motif_EF-hand-BS	MYH9 MYO9B SCN5A MYO18A	7.92e-04	90	86	4	IPR000048
Domain	IQ	MYH9 MYO9B SCN5A MYO18A	8.96e-04	93	86	4	PS50096
Domain	Hydrolase_3	ATP2B2 ATP2B3	9.21e-04	10	86	2	PF08282
Domain	PP2C_BS	PPM1E PPM1K	1.34e-03	12	86	2	IPR000222
Domain	PP2C_SIG	PPM1E PPM1K	1.84e-03	14	86	2	SM00331
Domain	PPM_1	PPM1E PPM1K	2.12e-03	15	86	2	PS01032
Domain	-	ATP2B2 ATP2B3	2.41e-03	16	86	2	1.20.1110.10
Domain	ATPase_P-typ_TM_dom	ATP2B2 ATP2B3	2.41e-03	16	86	2	IPR023298
Domain	ATPase_P-typ_cation-transptr_C	ATP2B2 ATP2B3	2.72e-03	17	86	2	IPR006068
Domain	Cation_ATPase_C	ATP2B2 ATP2B3	2.72e-03	17	86	2	PF00689
Domain	PP2C	PPM1E PPM1K	2.72e-03	17	86	2	IPR015655
Domain	Myosin_tail_1	MYH9 MYO18A	3.06e-03	18	86	2	PF01576
Domain	Cation_ATPase_N	ATP2B2 ATP2B3	3.06e-03	18	86	2	PF00690
Domain	Myosin_tail	MYH9 MYO18A	3.06e-03	18	86	2	IPR002928
Domain	Cation_ATPase_N	ATP2B2 ATP2B3	3.06e-03	18	86	2	SM00831
Domain	PP2C	PPM1E PPM1K	3.41e-03	19	86	2	PF00481
Domain	ATPase_P-typ_cation-transptr_N	ATP2B2 ATP2B3	3.41e-03	19	86	2	IPR004014
Domain	Myosin-like_IQ_dom	MYH9 MYO18A	3.41e-03	19	86	2	IPR027401
Domain	-	MYH9 MYO18A	3.41e-03	19	86	2	4.10.270.10
Domain	PP2Cc	PPM1E PPM1K	3.77e-03	20	86	2	SM00332
Domain	PPM-type_phosphatase_dom	PPM1E PPM1K	3.77e-03	20	86	2	IPR001932
Domain	-	PPM1E PPM1K	3.77e-03	20	86	2	3.60.40.10
Domain	PPM_2	PPM1E PPM1K	3.77e-03	20	86	2	PS51746
Domain	IQ	MYH9 MYO9B MYO18A	4.30e-03	71	86	3	PF00612
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KRT23 ROCK2 CCDC27 SMG1 MYH9 SYNE1 HNRNPM SYCP1 MYO18A PDAP1 HKDC1 MACF1 UGGT2 ATP2B2 TFAM ATP2B3 ADCY6 ESF1	2.62e-08	1442	90	18	35575683
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CUL4A MTUS1 TADA2B SCN5A PHRF1 HNRNPM SFXN2 MACF1 C16orf96 RIC8A TFAM ADCY6 PDZRN3 GATAD2B WWC1 RAD50	2.63e-08	1116	90	16	31753913
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BICD2 APPBP2 PHLDB1 ANKFY1 SEC24C SYNE1 PPM1E VPS8 MACF1 ADCY6	1.07e-07	407	90	10	12693553
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ROCK2 MYH9 ANKFY1 CTTNBP2 SEC24C CENPE SYNE1 HNRNPM MACF1 CDC5L GOLGA1 ITIH1 GATAD2B RAD50	1.82e-07	963	90	14	28671696
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	DNAJC4 THEM4 SEC24C SYNE1 PSMB2 ACBD5 HNRNPM CCDC18 MYO18A RTN3 MACF1 UGGT2 UFL1 CHD1 CDC5L TFAM ESF1	2.36e-07	1487	90	17	33957083
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	CUL4A MYH9 HNRNPM NUP88 CHD1 CDC5L PDZRN3 RAD50	2.97e-07	250	90	8	33536335
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ROCK2 BICD2 SEC24C PHRF1 MYO18A PDAP1 AFF1 UFL1 ADCY6 GATAD2B ESF1 RAD50	7.60e-07	774	90	12	15302935
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	ROCK2 SMG1 MYH9 SUPT5H SYNE1 HNRNPM MYO18A PDAP1 MACF1 CDC5L TFAM ESF1	1.17e-06	807	90	12	22681889
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SMG1 PHLDB1 ANKFY1 SYNE1 MACF1 CDC5L ADCY6	2.05e-06	225	90	7	12168954
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	CENPE SYNE1 HNRNPM SYCP1 MACF1 CDC5L RAD50	2.65e-06	234	90	7	36243803
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	SYNE1 PPM1E MACF1 CDC5L WWC1 CEP63	2.79e-06	151	90	6	17043677
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	BICD2 CENPE MYO9B SUPT5H AGFG1 PDAP1 RTN3 MACF1 RUFY1 RAD50	3.01e-06	588	90	10	38580884
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ROCK2 PHLDB1 MYH9 CTTNBP2 SEC24C SYNE1 ARHGAP26 HNRNPM MYO18A RTN3 MACF1 CDC5L ATP2B2 TFAM ATP2B3	3.84e-06	1431	90	15	37142655
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ORC2 MYH9 HNRNPM NUP88 AGFG1 PDAP1 MACF1 CHD1 STMN1 CDC5L ESF1 RAD50	5.26e-06	934	90	12	33916271
Pubmed	Localization of two genes encoding plasma membrane Ca2+ ATPases isoforms 2 (ATP2B2) and 3 (ATP2B3) to human chromosomes 3p26-->p25 and Xq28, respectively.	ATP2B2 ATP2B3	6.62e-06	2	90	2	8187550
Pubmed	Identification of novel MYO18A interaction partners required for myoblast adhesion and muscle integrity.	MYH9 MYO18A	6.62e-06	2	90	2	27824130
Pubmed	Defining the membrane proteome of NK cells.	ORC2 MYH9 MAN1A1 CENPE MYO9B PSMB2 ACBD5 PHRF1 HNRNPM MYO18A PARP9 CDC5L RAD50	9.67e-06	1168	90	13	19946888
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PHLDB1 MYH9 ANKFY1 SEC24C MYO9B PSMB2 HNRNPM MACF1 CHD1 RIC8A CDC5L TFAM ESF1 RAD50	9.70e-06	1353	90	14	29467282
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	CUL4A MYH9 SUPT5H PSMB2 GINS2 UFL1 CHD1 STMN1 CDC5L GATAD2B ESF1 RAD50	1.20e-05	1014	90	12	32416067
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	MYH9 SEC24C SUPT5H PSMB2 HNRNPM AGFG1 PDAP1 MACF1 STMN1 TFAM	1.50e-05	707	90	10	19738201
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	SYNE1 MACF1 CDC5L GATAD2B CEP63	1.56e-05	120	90	5	31413325
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	ROCK2 BICD2 ORC2 MYH9 ACBD5 PDAP1 UFL1 STMN1 RUFY1	1.69e-05	568	90	9	37774976
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	MYH9 ANKFY1 SUPT5H SYNE1 PSMB2 HNRNPM NUP88 RTN3 UFL1 CHD1 CDC5L ATP2B3 ESF1 RAD50	1.73e-05	1425	90	14	30948266
Pubmed	Structure of transcribing mammalian RNA polymerase II.	SUPT5H POLR2M	1.98e-05	3	90	2	26789250
Pubmed	Regulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factor.	RIC8A ADCY6	1.98e-05	3	90	2	17593019
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	CUL4A ROCK2 MYH9 ANKFY1 SEC24C SUPT5H PSMB2 HNRNPM NUP88 AGFG1 MACF1 GINS2 RIC8A RUFY1	2.18e-05	1455	90	14	22863883
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	MYH9 MYO9B HNRNPM MYO18A MACF1 UFL1 CHD1 RIC8A RAD50	2.64e-05	601	90	9	33658012
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	CUL4A ROCK2 MYH9 AGFG1 PDAP1 STMN1	2.78e-05	226	90	6	31452512
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SYNE1 METTL18 TADA2B PSMB2 ACBD5 PHRF1 MACF1 UFL1 CHD1 MPHOSPH6 TFAM CEP164 GATAD2B ESF1	2.98e-05	1497	90	14	31527615
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	CUL4A ORC2 HNRNPM AGFG1 PDAP1 CHD1 CDC5L C2orf49 TFAM GATAD2B ESF1	3.61e-05	954	90	11	36373674
Pubmed	Orc2 protects ORCA from ubiquitin-mediated degradation.	CUL4A ORC2	3.96e-05	4	90	2	22935713
Pubmed	Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.	ATP2B2 ATP2B3	3.96e-05	4	90	2	12209837
Pubmed	Expression and role of calcium-ATPase pump and sodium-calcium exchanger in differentiated trophoblasts from human term placenta.	ATP2B2 ATP2B3	3.96e-05	4	90	2	12784250
Pubmed	Calcium pumps of plasma membrane and cell interior.	ATP2B2 ATP2B3	3.96e-05	4	90	2	15101689
Pubmed	UV-dependent interaction between Cep164 and XPA mediates localization of Cep164 at sites of DNA damage and UV sensitivity.	ORC2 CEP164	3.96e-05	4	90	2	19197159
Pubmed	The plasma membrane calcium pump in health and disease.	ATP2B2 ATP2B3	3.96e-05	4	90	2	23413890
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B2 ATP2B3	3.96e-05	4	90	2	8245032
Pubmed	Plasma membrane calcium ATPases as critical regulators of calcium homeostasis during neuronal cell function.	ATP2B2 ATP2B3	3.96e-05	4	90	2	10577388
Pubmed	Structural organization, ion transport, and energy transduction of P-type ATPases.	ATP2B2 ATP2B3	3.96e-05	4	90	2	8634322
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B2 ATP2B3	3.96e-05	4	90	2	7989379
Pubmed	Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps.	ATP2B2 ATP2B3	3.96e-05	4	90	2	11152753
Pubmed	PMCA1 depletion in mouse eggs amplifies calcium signaling and impacts offspring growth†.	ATP2B2 ATP2B3	3.96e-05	4	90	2	36130203
Pubmed	Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse.	ATP2B2 ATP2B3	3.96e-05	4	90	2	10434059
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	ROCK2 SMG1 MYH9 SEC24C MACF1 RIC8A STMN1 RAD50	4.64e-05	498	90	8	36634849
Pubmed	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.	ORC2 GINS2 RAD50	4.69e-05	27	90	3	17525332
Pubmed	Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord.	SEC24C PHRF1 MACF1	4.69e-05	27	90	3	19026994
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYH9 SEC24C SUPT5H PHRF1 NUP88 MACF1 CHD1 ESF1 RAD50	5.01e-05	653	90	9	22586326
Pubmed	Differential regulation of the apical plasma membrane Ca(2+) -ATPase by protein kinase A in parotid acinar cells.	ATP2B2 ATP2B3	6.59e-05	5	90	2	17938178
Pubmed	The Rho-Rock-Myosin signaling axis determines cell-cell integrity of self-renewing pluripotent stem cells.	ROCK2 MYH9	6.59e-05	5	90	2	18714354
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	PHLDB1 SEC24C MYO9B SUPT5H SYNE1 MACF1 UFL1 CHD1 CDC5L TFAM RAD50	6.81e-05	1024	90	11	24711643
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	BICD2 MTUS1 CENPE NUP88 PDAP1 POC5 RUFY1 PDZRN3 CEP164 RAD50	7.29e-05	853	90	10	28718761
Pubmed	Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.	CUL4A MAN1A1 SEC24C CHD1 STMN1 GCK	8.43e-05	276	90	6	28319085
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	ORC2 MYH9 SUPT5H PDAP1 STMN1 ESF1	9.67e-05	283	90	6	30585729
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	CUL4A HNRNPM NUP88 CHD1 CDC5L GATAD2B RAD50	9.84e-05	411	90	7	35182466
Pubmed	Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange.	ATP2B2 ATP2B3	9.87e-05	6	90	2	12767889
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	KRT23 ROCK2 MYH9 ANKFY1 PSMB2 HNRNPM CDC5L TFAM	1.02e-04	558	90	8	27591049
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	MYH9 SEC24C SUPT5H SYNE1 HNRNPM MYO18A PDAP1 MACF1 UFL1 CDC5L TFAM	1.11e-04	1082	90	11	38697112
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	CUL4A ORC2 MYH9 SUPT5H TADA2B PHRF1 HNRNPM NUP88 CDC5L TFAM GATAD2B RAD50	1.26e-04	1294	90	12	30804502
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	PHLDB1 SYNE1 SCN5A HNRNPM MYO18A	1.29e-04	187	90	5	26460568
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	ROCK2 ORC2 MYH9 SEC24C HNRNPM MACF1 CDC5L RAD50	1.36e-04	582	90	8	20467437
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	ORC2 SEC24C PSMB2 HNRNPM CDC5L TFAM GATAD2B RAD50	1.38e-04	583	90	8	29844126
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SYNE1 VPS8 MACF1 UFL1	1.41e-04	101	90	4	9872452
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ROCK2 BICD2 PHLDB1 ARHGAP26	1.47e-04	102	90	4	9734811
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ANKFY1 MTUS1 SYNE1 MACF1	1.52e-04	103	90	4	10574462
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	MYH9 HNRNPM NUP88 CDC5L GATAD2B	1.57e-04	195	90	5	19454010
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	MYH9 SYNE1 MACF1 ATP2B3 RAD50	1.65e-04	197	90	5	20811636
Pubmed	Characterization of the DOT1L network: implications of diverse roles for DOT1L.	HNRNPM AFF1 CHD1	1.66e-04	41	90	3	20431927
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	CUL4A ORC2 SEC24C SUPT5H PSMB2 HNRNPM NUP88 MPHOSPH6 CDC5L TFAM GATAD2B RAD50	1.68e-04	1335	90	12	29229926
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	BICD2 MYH9 ACBD5 HNRNPM NUP88 MYO18A PDAP1 RTN3 MACF1 STMN1 GATAD2B	1.73e-04	1139	90	11	36417873
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD18A ANKRD18B	1.84e-04	8	90	2	12634303
Pubmed	Gene knockout studies of Ca2+-transporting ATPases.	ATP2B2 ATP2B3	1.84e-04	8	90	2	10951186
Pubmed	ABCE1 is a highly conserved RNA silencing suppressor.	CUL4A MACF1 C16orf96 UFL1 TFAM	1.94e-04	204	90	5	25659154
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	ROCK2 MYO18A CHD1 TSKS ATP2B2 ADCY6 ITIH1 GATAD2B	2.12e-04	621	90	8	22794259
Pubmed	The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.	MYH9 HNRNPM MYO18A STMN1 TFAM RAD50	2.15e-04	328	90	6	23398456
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	KRT23 SMG1 MYH9 TADA2B HNRNPM MYO18A TFAM RAD50	2.24e-04	626	90	8	33644029
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	CUL4A SUPT5H SYNE1 NUP88 PDAP1 ESF1	2.30e-04	332	90	6	25693804
Pubmed	Ataxin 10 induces neuritogenesis via interaction with G-protein beta2 subunit.	ABCA1 GOLGA1	2.36e-04	9	90	2	16498633
Pubmed	Expression of mRNA and protein-protein interaction of the antiviral endoribonuclease RNase L in mouse spleen.	MYH9 GAS8	2.36e-04	9	90	2	24780566
Pubmed	A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation.	MYH9 HNRNPM UFL1	2.50e-04	47	90	3	32160526
Pubmed	Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.	ROCK2 BICD2 SYNE1 VPS8 AGFG1 RUFY1	2.57e-04	339	90	6	37232246
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	BICD2 PHLDB1 RTN3 WWC1 CEP63	2.64e-04	218	90	5	33378226
Pubmed	A human MAP kinase interactome.	KRT23 MYH9 SYNE1 HNRNPM MYO18A AGFG1 MACF1	2.74e-04	486	90	7	20936779
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	CUL4A ROCK2 MYH9 SEC24C PSMB2 HNRNPM PDAP1 MACF1 UFL1 CHD1 CDC5L RAD50	2.87e-04	1415	90	12	28515276
Pubmed	Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma.	ABCA1 ITIH1	2.94e-04	10	90	2	25173105
Pubmed	Proteomics identifies the developmental regulation of HKDC1 in liver of pigs and mice.	HKDC1 GCK	2.94e-04	10	90	2	37545422
Pubmed	ANXA1-derived peptide for targeting PD-L1 degradation inhibits tumor immune evasion in multiple cancers.	MYH9 PARP9 CDC5L	3.01e-04	50	90	3	37001908
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	ORC2 APPBP2 PDAP1 HKDC1 RILPL1 ADCY6 CEP164 GATAD2B ANKRD18B WWC1	3.12e-04	1021	90	10	26760575
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	MYH9 SUPT5H HNRNPM NUP88 MYO18A MACF1 CDC5L TFAM	3.19e-04	660	90	8	32780723
Pubmed	Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.	APPBP2 ANKFY1 UFL1 CHD1 PARP9	3.24e-04	228	90	5	30471916
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	ROCK2 BICD2 MYH9 HNRNPM NUP88 STMN1 GATAD2B	3.37e-04	503	90	7	16964243
Pubmed	Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.	SMG1 CDC5L ADCY6	3.38e-04	52	90	3	9455477
Pubmed	Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.	CTTNBP2 ACBD5 CHD1 TFAM	3.50e-04	128	90	4	25332235
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	BICD2 PHLDB1 SEC24C HNRNPM AGFG1 PDAP1 RTN3 POLR2M POC5 WWC1	3.55e-04	1038	90	10	26673895
Pubmed	The Hippo pathway component Wwc2 is a key regulator of embryonic development and angiogenesis in mice.	FLT1 WWC1	3.59e-04	11	90	2	33483469
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	ORC2 MYO9B SFXN2 UFL1 CDC5L RAD50	3.75e-04	364	90	6	24778252
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	CUL4A ROCK2 MYH9 SEC24C MYO9B PSMB2 HNRNPM AFF1 CDC5L WWC1 ESF1	3.76e-04	1247	90	11	27684187
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MTUS1 SUPT5H PSMB2 PPM1E ACBD5 CCDC18 POC5 PPM1K CDC5L ESF1	3.85e-04	1049	90	10	27880917
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	SEC24C VPS8 CCDC18 NUP88 CEP63	5.02e-04	251	90	5	29778605
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	MYH9 PSMB2 AGFG1 MACF1 CHD1 STMN1 ATP2B2	5.04e-04	538	90	7	28524877
Pubmed	Transcriptional and posttranscriptional regulation of HIV-1 gene expression.	SUPT5H AFF1	5.07e-04	13	90	2	22355797
Interaction	SYCE1 interactions	BICD2 CCDC18 SYCP1 POLR2M RUFY1 GOLGA1 RAD50	1.39e-06	127	88	7	int:SYCE1
Interaction	PCM1 interactions	BICD2 CENPE SUPT5H GAS8 CCDC18 POC5 STMN1 PDZRN3 GOLGA1 CEP164 CEP63	2.94e-06	434	88	11	int:PCM1
Interaction	CIT interactions	ORC2 MYH9 SEC24C MYO9B SUPT5H SYNE1 HNRNPM NUP88 MYO18A EMILIN2 MACF1 CHD1 RIC8A STMN1 MPHOSPH6 CDC5L TFAM GATAD2B WWC1 ESF1	3.29e-06	1450	88	20	int:CIT
Interaction	TNIK interactions	BICD2 CTTNBP2 SEC24C SYNE1 PPM1E MACF1 CDC5L GATAD2B WWC1 CEP63	6.31e-06	381	88	10	int:TNIK
Interaction	NDC80 interactions	ROCK2 BICD2 CENPE ACBD5 CCDC18 CDC5L CEP164 RAD50 CEP63	8.91e-06	312	88	9	int:NDC80
Interaction	PCNT interactions	ANKFY1 SYNE1 ACBD5 CCDC18 MACF1 CDC5L GOLGA1 CEP63	1.05e-05	241	88	8	int:PCNT
Interaction	PLEC interactions	KRT23 BICD2 CCDC27 MYH9 CTTNBP2 HNRNPM NUP88 MYO18A MACF1 CDC5L	1.80e-05	430	88	10	int:PLEC
Interaction	OFD1 interactions	CENPE SUPT5H CCDC18 POC5 PDZRN3 GOLGA1 CEP164 RAD50 CEP63	2.07e-05	347	88	9	int:OFD1
Interaction	SYNE3 interactions	BICD2 CENPE CCDC18 NUP88 RTN3 MACF1 UGGT2 UFL1 CEP164 CEP63	2.37e-05	444	88	10	int:SYNE3
Interaction	SHANK3 interactions	ROCK2 PHLDB1 CTTNBP2 SYNE1 NUP88 PDAP1 RTN3 MACF1 ATP2B2 ITIH1	6.03e-05	496	88	10	int:SHANK3
Interaction	DCTN1 interactions	CUL4A BICD2 ANKFY1 MTUS1 CENPE MACF1 UFL1 RIC8A RUFY1 WWC1	6.14e-05	497	88	10	int:DCTN1
Interaction	PRC1 interactions	BICD2 ORC2 IQCA1L MYH9 SEC24C CENPE SYNE1 HNRNPM MYO18A CHD1 RIC8A CDC5L TFAM ESF1	7.79e-05	973	88	14	int:PRC1
Interaction	DYNC1LI1 interactions	CUL4A BICD2 FLT1 CDC5L RUFY1 RAD50 CEP63	1.02e-04	246	88	7	int:DYNC1LI1
Interaction	DISC1 interactions	SYNE1 PPM1E GAS8 PDAP1 MACF1 CDC5L CEP164 GATAD2B CEP63	1.07e-04	429	88	9	int:DISC1
Interaction	TERF2 interactions	ORC2 MYH9 SUPT5H SYNE1 TADA2B MACF1 ATP2B3 RAD50	1.20e-04	340	88	8	int:TERF2
Interaction	VPS33A interactions	BICD2 SEC24C VPS8 NUP88 UFL1 CDC5L CEP63	1.21e-04	253	88	7	int:VPS33A
Interaction	MYL6 interactions	MYH9 MYO9B ACBD5 MYO18A UFL1 STMN1 RUFY1	1.27e-04	255	88	7	int:MYL6
Interaction	H3C1 interactions	CUL4A ROCK2 ORC2 MYH9 SYNE1 TADA2B MYO18A UGGT2 CHD1 GATAD2B ANKRD18B WWC1 RAD50	1.40e-04	901	88	13	int:H3C1
Interaction	C3orf18 interactions	SMG1 VPS8 UFL1 ATP2B2 ATP2B3	1.49e-04	115	88	5	int:C3orf18
Interaction	CLTB interactions	ROCK2 BICD2 MYH9 MYO18A AGFG1 PDAP1	1.60e-04	185	88	6	int:CLTB
Interaction	KIF11 interactions	ORC2 ANKFY1 MTUS1 ACBD5 UFL1 CDC5L RUFY1	1.69e-04	267	88	7	int:KIF11
Interaction	MYL3 interactions	CUL4A MYH9 MYO18A	1.73e-04	25	88	3	int:MYL3
Interaction	WHAMMP3 interactions	BICD2 CENPE SYNE1 GOLGA1 CEP63	1.75e-04	119	88	5	int:WHAMMP3
Interaction	FXR1 interactions	CUL4A ORC2 SMG1 PHLDB1 MYH9 ANKFY1 SEC24C HNRNPM UFL1 CDC5L CEP63	1.78e-04	679	88	11	int:FXR1
Interaction	CEP43 interactions	SUPT5H TADA2B CCDC18 GOLGA1 RAD50 CEP63	1.85e-04	190	88	6	int:CEP43
Interaction	XRCC6 interactions	CUL4A ORC2 FLT1 MYH9 SUPT5H PHRF1 HNRNPM PDAP1 UFL1 STMN1 RUFY1 ESF1 RAD50	1.88e-04	928	88	13	int:XRCC6
Interaction	ROCK1 interactions	CUL4A ROCK2 TAOK3 ANKFY1 UFL1 RUFY1	1.96e-04	192	88	6	int:ROCK1
Interaction	WASHC2A interactions	ROCK2 ANKFY1 SUPT5H ACBD5 GOLGA1	1.96e-04	122	88	5	int:WASHC2A
Interaction	CAPZA1 interactions	BICD2 MYH9 HNRNPM MYO18A UFL1 CDC5L RUFY1 RAD50	1.99e-04	366	88	8	int:CAPZA1
Interaction	SLAIN2 interactions	BICD2 APPBP2 ANKFY1 TSKS GOLGA1	2.20e-04	125	88	5	int:SLAIN2
Interaction	CCDC18 interactions	CCDC18 POC5 GOLGA1 CEP63	2.23e-04	68	88	4	int:CCDC18
Interaction	SLFN11 interactions	MYH9 PPM1E HNRNPM NUP88 CHD1 CDC5L PDZRN3 RAD50	2.39e-04	376	88	8	int:SLFN11
Interaction	ILF2 interactions	CUL4A ORC2 SUPT5H HNRNPM SFXN2 UFL1 MPHOSPH6 CDC5L RUFY1 RAD50	2.49e-04	590	88	10	int:ILF2
GeneFamily	ATPases Ca2+ transporting	ATP2B2 ATP2B3	3.23e-04	9	55	2	1209
GeneFamily	Protein phosphatases, Mg2+/Mn2+ dependent	PPM1E PPM1K	1.20e-03	17	55	2	701
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	CENPE PHRF1 TSKS WWC1	2.23e-03	181	55	4	694
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	ANKFY1 RUFY1	3.99e-03	31	55	2	81
GeneFamily	Ankyrin repeat domain containing	ANKFY1 CTTNBP2 ANKRD18A ANKRD18B	6.26e-03	242	55	4	403
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	TADA2B CDC5L	1.13e-02	53	55	2	532
Coexpression	LAKE_ADULT_KIDNEY_C24_ENDOTHELIAL_CELLS_AEA_AND_DVR	ROCK2 FLT1 MYH9 MTUS1 SYNE1 ARHGAP26 MACF1	9.59e-07	152	90	7	M39243
Coexpression	CUI_TCF21_TARGETS_2_DN	BICD2 FLT1 CTTNBP2 MAN1A1 MTUS1 ARHGAP26 TADA2B ACBD5 MYO18A AGFG1 MACF1 POLR2M RILPL1 PPM1K	1.96e-06	888	90	14	MM1018
Coexpression	TBK1.DF_DN	ROCK2 SMG1 ANKFY1 AGFG1 UFL1 TFAM ADCY6 ESF1	6.51e-06	286	90	8	M2864
Coexpression	CUI_TCF21_TARGETS_2_DN	BICD2 FLT1 CTTNBP2 MAN1A1 MTUS1 ARHGAP26 TADA2B ACBD5 MYO18A AGFG1 MACF1 RILPL1 PPM1K	6.91e-06	854	90	13	M1533
ToppCell	COVID-19_Severe-gd_T\|COVID-19_Severe / Disease condition and Cell class	MYH9 MAN1A1 MYO9B SYNE1 ARHGAP26 MACF1	2.02e-06	184	90	6	791f1bcb954aadc63d4117c400537d036f68734d
ToppCell	Control-Myeloid-cMonocyte\|Control / Disease state, Lineage and Cell class	FLT1 MYO9B ARHGAP26 EMILIN2 AGFG1 CHD1	2.58e-06	192	90	6	ad04c9c4bdebf94615cee1904ca48197e62c923b
ToppCell	Control-Myeloid-cMonocyte\|World / Disease state, Lineage and Cell class	FLT1 MYO9B ARHGAP26 EMILIN2 AGFG1 CHD1	2.74e-06	194	90	6	f852f5258617a66a4fbd56d64c7b47272e7b8b60
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	CENPE CCDC18 ANKRD18A CEP164 ESF1 RAD50	2.99e-06	197	90	6	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	SMG1 MYH9 MYO9B EMILIN2 CHD1 PARP9	3.08e-06	198	90	6	61ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BICD2 FLT1 SYNE1 ACBD5 AGFG1	2.39e-05	169	90	5	41ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BICD2 FLT1 SYNE1 ACBD5 AGFG1	2.39e-05	169	90	5	42782c61592742190ab0cba8a94f8bdf9c278f90
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT23 GAS8 CCDC18 STMN1 ATP2B3	2.75e-05	174	90	5	a0ccda8fd6f55251cdeff24cf66e72e4a31d2104
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROCK2 SMG1 ARHGAP26 MACF1 CHD1	3.41e-05	182	90	5	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	Control-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	FLT1 PHLDB1 MYH9 SYNE1 PDZRN3	3.98e-05	188	90	5	88b3415e33db81726dd29c1f50c886e057af50a0
ToppCell	Control-PLT_1\|World / Disease Group and Platelet Clusters	ROCK2 BICD2 TAOK3 RILPL1 RUFY1	4.40e-05	192	90	5	f595eba81911eb860dce964f1d8269287f50d3ea
ToppCell	COVID-19-Myeloid-Transitioning_MDM\|COVID-19 / group, cell type (main and fine annotations)	ABCA1 MYO9B ARHGAP26 VPS8 EMILIN2	4.85e-05	196	90	5	4929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA1 TAOK3 MYO9B ARHGAP26 EMILIN2	4.97e-05	197	90	5	8af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCell	COVID-19-kidney-Macrophages\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCA1 TAOK3 MYO9B ARHGAP26 EMILIN2	4.97e-05	197	90	5	3912301018d0863144dcfac8d1fa8adc081748d7
ToppCell	ILEUM-inflamed-(5)_Plasma-(5)_Plasmablasts\|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CENPE PSMB2 PDAP1 GINS2 STMN1	5.22e-05	199	90	5	624a807fae0a080a4e6755dcb374c25b6f2d2cfe
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA1 CTTNBP2 MYO9B EMILIN2 PLCB2	5.22e-05	199	90	5	f34c15df58fbdc6c90e30800e26fabbf828ad10b
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	KRT23 ROCK2 ANKRD18A ANKRD18B RAD50	5.22e-05	199	90	5	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Mild / Disease, condition lineage and cell class	THEM4 ANKRD18A PARP9 PPM1K ANKRD18B	5.34e-05	200	90	5	d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	MYH9 SYNE1 MACF1 PARP9 RAD50	5.34e-05	200	90	5	2281debd86e5d92e8fe0397aec9ef670800f7471
Disease	hyperinsulinemic hypoglycemia (implicated_via_orthology)	HKDC1 GCK	8.54e-05	5	87	2	DOID:13317 (implicated_via_orthology)
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2B2 ATP2B3	1.28e-04	6	87	2	DOID:0050429 (implicated_via_orthology)
Disease	maturity-onset diabetes of the young (implicated_via_orthology)	HKDC1 GCK	3.81e-04	10	87	2	DOID:0050524 (implicated_via_orthology)
Disease	PR interval	MTUS1 SCN5A EMILIN2 AFF1 MACF1 CDC5L PDZRN3	6.59e-04	495	87	7	EFO_0004462
Disease	neutrophil count	CUL4A BICD2 THEM4 SUPT5H ARHGAP26 TADA2B NUP88 SYCP1 SFXN2 AFF1 PLCB2 POC5	7.30e-04	1382	87	12	EFO_0004833
Disease	hyperglycemia (implicated_via_orthology)	HKDC1 GCK	1.14e-03	17	87	2	DOID:4195 (implicated_via_orthology)
Disease	neuroimaging measurement	CTTNBP2 SEC14L6 SYCP1 AFF1 MACF1 CDC5L RUFY1 PDZRN3 GATAD2B WWC1	1.20e-03	1069	87	10	EFO_0004346
Disease	triglyceride measurement, high density lipoprotein cholesterol measurement	ABCA1 AFF1 POLR2M GCK RILPL1	1.32e-03	274	87	5	EFO_0004530, EFO_0004612
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	ABCA1 AFF1 MACF1 POLR2M POC5	1.37e-03	276	87	5	EFO_0004612, EFO_0020943
Disease	free cholesterol in large HDL measurement	ABCA1 POC5 RILPL1	1.67e-03	79	87	3	EFO_0022157
Disease	Arthrogryposis	BICD2 VPS8	1.74e-03	21	87	2	C0003886
Disease	post-traumatic stress disorder symptom measurement	CTTNBP2 SYNE1 POLR2M	1.85e-03	82	87	3	EFO_0008535
Disease	cortical surface area measurement	ROCK2 BICD2 CTTNBP2 MYO9B AGFG1 AFF1 MACF1 CDC5L PDZRN3 GATAD2B WWC1	1.98e-03	1345	87	11	EFO_0010736
Disease	gestational diabetes	HKDC1 PPM1K	2.09e-03	23	87	2	EFO_0004593
Disease	phospholipids:total lipids ratio, high density lipoprotein cholesterol measurement	ABCA1 AFF1 MACF1 POC5 RILPL1	2.17e-03	307	87	5	EFO_0004612, EFO_0020946
Disease	tobacco smoke exposure measurement	MYO18A C2orf49	2.27e-03	24	87	2	EFO_0009115
Disease	glucose tolerance test	HKDC1 GCK	2.88e-03	27	87	2	EFO_0004307
Disease	metabolic syndrome	ABCA1 AFF1 POC5 GCK	2.94e-03	200	87	4	EFO_0000195

Protein segments in the cluster

Peptide	Gene	Start	Entry
GKMMEKKREQHEIKN	C2orf49	71	Q9BVC5
RDAERVKEMKRMHKA	CDC5L	526	Q99459
VKEMKRMHKAVQKDL	CDC5L	531	Q99459
KTHMEKDMVELGKLQ	ANKRD18A	806	Q8IVF6
MMKLRNELKALKEDA	BICD2	726	Q8TD16
EDINTKKEDMMFHKI	ADCY6	356	O43306
MMKKSADHKNLEVIV	ACBD5	221	Q5T8D3
KGLSEKHVKAEMEQM	ABCA1	1001	O95477
MLEEKVLNLKTHMEK	ANKRD18B	806	A2A2Z9
SMRKFKEAEEMHIKA	APPBP2	441	Q92624
LMHKLQEEKAFREEM	CCDC70	41	Q6NSX1
AKKKMVLDHLVIQRM	CHD1	926	O14646
VKKMMKDNNLVRHLD	ATP2B2	471	Q01814
KKMMKDNNLVRHLDA	ATP2B3	446	Q16720
DKKHQEMMGLIEKDN	CCDC27	491	Q2M243
DRKEMNILELSHKKM	PDZRN3	1011	Q9UPQ7
HMEKCIMDLLPKEKN	PPM1K	141	Q8N3J5
EKHKEKINEDMRLMR	RAD50	991	Q92878
AAFQRKKKMMEEKLH	PARP9	681	Q8IXQ6
MLDDRARMEAAKKEK	GCK	1	P35557
MAEEEVAKLEKHLML	ANKFY1	1	Q9P2R3
MEMRKEKEKHAAHLK	POC5	191	Q8NA72
HMLLKKEESLGKMEQ	GOLGA1	186	Q92805
EMKKLLRERGHMLEN	ITIH1	546	P19827
EKQKAKERYMKMHLA	PDAP1	116	Q13442
MLEKRQMDRAEHKGE	WWC1	1046	Q8IX03
EELKARMDKHMAISR	MTUS1	1186	Q9ULD2
MEESMKKAAEVLNKH	HNRNPM	121	P52272
NHYKKKMEVMDLHRK	CCDC178	286	Q5BJE1
MLNRKFKKEELLDMD	ESF1	521	Q9H501
DMKDALKKLMRFHHK	OR2W1	296	Q9Y3N9
DQEDMNELMKKHKAA	MYO18A	1751	Q92614
MKKLHMQERAVEEVK	PHRF1	1561	Q9P1Y6
KELILMKKHHEQEME	KRT23	201	Q9C075
EMEKLNHQGELMLKK	MACF1	2296	O94854
KEHAMPKDLKKMLEN	METTL18	101	O95568
TLHAQVADMKKKMED	MYH9	1361	P35579
DVLAKRLKMEGHEAM	GATAD2B	26	Q8WXI9
AIKNMRRKMEDKHVC	PPM1E	236	Q8WY54
HAARMEYKDLREKMK	CCDC175	351	P0C221
KLRKMVEGHDEVMAK	C16orf96	126	A6NNT2
YKEELSKMEKEIMHL	CCDC18	876	Q5T9S5
SKMEKEIMHLKRDGE	CCDC18	881	Q5T9S5
HTTDLKEEIDKMRKM	CTTNBP2	251	Q8WZ74
MEKRLRAEMQKAEDK	CEP63	441	Q96MT8
KDMELSKDIMVHFKQ	CUL4A	496	Q13619
RKVKQMHLNFMDEKD	DNAJC4	176	Q9NNZ3
AIREKRAKIKEMMKH	MAN1A1	191	P33908
GDERVMMELNHLKDK	EMILIN2	531	Q9BXX0
EKKPHYMEVLEMRAK	POLR2M	226	P0CAP2
DKMEMLFKHFLVEDK	SEC24C	1056	P53992
KSEDMLRKHMEFRKQ	SEC14L6	51	B5MCN3
KLHENLEEMKSVMKE	CENPE	1876	Q02224
EKQEDIMNRMKKLLH	NUP88	631	Q99567
MSKPELKEDKMLEVH	ORC2	1	Q13416
KEGKDHLDLLDMKKM	RTN3	116	O95197
IMERLEKLHFMQKVK	SFXN2	246	Q96NB2
VASKDDVKMMKLHLE	SYNE1	1726	Q8NF91
DVKMMKLHLEQLDER	SYNE1	1731	Q8NF91
ENMHKEKMLRAKIRE	TADA2B	276	Q86TJ2
KAMRRHKDMDVDILA	HKDC1	191	Q2TB90
KLMLQMNAKHKAEEV	MPHOSPH6	86	Q99547
MKHRMDQLEAEEAKL	IQCA1L	796	A6NCM1
MEIAMKLLEKDTHEK	RUFY1	431	Q96T51
MDVEKLEKMRDHERK	GINS2	66	Q9Y248
EKIAIMREKHTALMK	SMG1	2001	Q96Q15
VESLMKKMKENPLEH	ARHGAP26	246	Q9UNA1
DHDKMFKMSEKILLL	PSMB2	31	P49721
EKRFQEAMEMLKKEH	SCN5A	431	Q14524
NKKRTQKEMEHAMLI	TAOK3	636	Q9H2K8
MKDLIVHFQDKKLME	VPS8	636	Q8N3P4
NKITIMPKHEDLKDM	SUPT5H	446	O00267
IMSLEKEIMDKHLKR	TFAM	126	Q00059
KEHEAMKLVTMFDKL	RIC8A	476	Q9NPQ8
MAEEKLTHKMEANKE	STMN1	96	P16949
KQQADLHMREAKKMK	AFF1	961	P51825
LHMREAKKMKQKAEL	AFF1	966	P51825
KRKQEEKHLKMLRDM	AGFG1	6	P52594
LDKMKEEHQQVMAKA	CEP164	851	Q9UPV0
MRKNLEKETRHLDEM	CEP164	1161	Q9UPV0
DELISMKEMAEKDHK	C10orf67	286	Q8IYJ2
KHEGMSERERQVMKK	RILPL1	151	Q5EBL4
KTHFLDPKLMKEEQM	THEM4	91	Q5T1C6
KIAEMVALMEKHKHQ	SYCP1	706	Q15431
KELEIKEMMARHKQE	ROCK2	946	O75116
KEMMARHKQELTEKD	ROCK2	951	O75116
DKMKPEEKMATLDHL	TSKS	536	Q9UJT2
GKIEEMEKMLKEAHA	PHLDB1	1146	Q86UU1
MEKMLKEAHAEKNRL	PHLDB1	1151	Q86UU1
KMMELAREKQAAELK	PLCB2	1016	Q00722
LEKEKEPCKMKRHEM	ZNF429	56	Q86V71
EPFKHEEMNIKELKM	UGGT2	626	Q9NYU1
NKDAALHMEPKKEKM	FLT1	931	P17948
FRELMHQKAEKEMKN	UFL1	376	O94874
MALSDVDVKKQIKHM	ATP6V1E2	1	Q96A05
LKEQMEDMRKKEDHL	GAS8	251	O95995
DLKHDFERLKQAMEM	MYO9B	376	Q13459