Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2

1.20e-074593PF14914
DomainLRRC37_N

LRRC37A LRRC37A3 LRRC37A2

1.20e-074593IPR032754
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2

1.20e-074593IPR029423
DomainLRRC37

LRRC37A LRRC37A3 LRRC37A2

1.20e-074593PF15779
DomainLRRC37A/B-like

LRRC37A LRRC37A3 LRRC37A2

1.20e-074593IPR015753
DomainICAM

ICAM5 ICAM3

5.86e-054592IPR003988
DomainICAM_N

ICAM5 ICAM3

9.75e-055592IPR013768
DomainICAM_N

ICAM5 ICAM3

9.75e-055592PF03921
DomainICAM_VCAM_N

ICAM5 ICAM3

1.46e-046592IPR003987
DomainLDLR_class-A_CS

TMPRSS15 SSPOP ST14

2.72e-0440593IPR023415
DomainLdl_recept_a

TMPRSS15 SSPOP ST14

3.87e-0445593PF00057
Domain-

TMPRSS15 SSPOP ST14

4.13e-04465934.10.400.10
DomainLDLRA_1

TMPRSS15 SSPOP ST14

4.68e-0448593PS01209
DomainLDLRA_2

TMPRSS15 SSPOP ST14

4.98e-0449593PS50068
DomainLDrepeatLR_classA_rpt

TMPRSS15 SSPOP ST14

4.98e-0449593IPR002172
DomainLDLa

TMPRSS15 SSPOP ST14

4.98e-0449593SM00192
DomainSEA

TMPRSS15 ST14

2.18e-0322592PF01390
DomainG_patch

SUGP2 RBM6

2.38e-0323592SM00443
DomainG_patch_dom

SUGP2 RBM6

2.38e-0323592IPR000467
DomainG_PATCH

SUGP2 RBM6

2.38e-0323592PS50174
DomainSEA

TMPRSS15 ST14

2.38e-0323592PS50024
DomainG-patch

SUGP2 RBM6

2.38e-0323592PF01585
DomainSEA_dom

TMPRSS15 ST14

2.38e-0323592IPR000082
DomainTGFb_propeptide

MSTN GDF11

3.52e-0328592PF00688
DomainTGF-b_N

MSTN GDF11

3.52e-0328592IPR001111
DomainLRR

NLRP12 LRRC37A LRRC37A3 LRRC37A2

3.73e-03201594PS51450
DomainZnF_U1

ZFHX4 ZNF407

3.77e-0329592SM00451
DomainZnf_U1

ZFHX4 ZNF407

3.77e-0329592IPR003604
DomainTGF-beta-rel

MSTN GDF11

4.58e-0332592IPR015615
DomainTGFb_CS

MSTN GDF11

4.58e-0332592IPR017948
DomainConA-like_dom

TMPRSS15 CELSR1 TRIM58 RNF39

5.06e-03219594IPR013320
Domainzf-C3HC4

RAPSN TRIM58 VPS8 RNF39

5.39e-03223594PF00097
DomainTGFB

MSTN GDF11

6.09e-0337592SM00204
DomainTGF-b_C

MSTN GDF11

6.09e-0337592IPR001839
DomainTGF_BETA_2

MSTN GDF11

6.09e-0337592PS51362
DomainTGF_beta

MSTN GDF11

6.09e-0337592PF00019
DomainTGF_BETA_1

MSTN GDF11

6.09e-0337592PS00250
DomainPRY

TRIM58 RNF39

7.79e-0342592PF13765
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A LRRC37A3 LRRC37A2

1.85e-08459322419166
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A LRRC37A3 LRRC37A2

5.52e-071059323064749
Pubmed

GDF11 promotes osteogenesis as opposed to MSTN, and follistatin, a MSTN/GDF11 inhibitor, increases muscle mass but weakens bone.

MSTN GDF11

2.83e-06259232071240
Pubmed

The Growth Differentiation Factor 11 (GDF11) and Myostatin (MSTN) in tissue specific aging.

MSTN GDF11

2.83e-06259228472635
Pubmed

Relationship between serum level of growth differentiation factors 8, 11 and bone mineral density in girls with anorexia nervosa.

MSTN GDF11

2.83e-06259230281844
Pubmed

Circulating Growth Differentiation Factor 11/8 Levels Decline With Age.

MSTN GDF11

2.83e-06259226489925
Pubmed

Functional substitutions of amino acids that differ between GDF11 and GDF8 impact skeletal development and skeletal muscle.

MSTN GDF11

2.83e-06259236631218
Pubmed

Apoptotic cell-derived ICAM-3 promotes both macrophage chemoattraction to and tethering of apoptotic cells.

ICAM5 ICAM3

2.83e-06259222117198
Pubmed

Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease.

MSTN GDF11

2.83e-06259227304512
Pubmed

Reduced Circulating GDF11 Is Unlikely Responsible for Age-Dependent Changes in Mouse Heart, Muscle, and Brain.

MSTN GDF11

2.83e-06259226372181
Pubmed

Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation.

MSTN GDF11

2.83e-06259227034275
Pubmed

Supraphysiological levels of GDF11 induce striated muscle atrophy.

MSTN GDF11

2.83e-06259228270449
Pubmed

Essential amino acids increase microRNA-499, -208b, and -23a and downregulate myostatin and myocyte enhancer factor 2C mRNA expression in human skeletal muscle.

MSTN MEF2C

2.83e-06259219828686
Pubmed

Redundancy of myostatin and growth/differentiation factor 11 function.

MSTN GDF11

2.83e-06259219298661
Pubmed

Myostatin and the control of skeletal muscle mass.

MSTN GDF11

2.83e-06259210508689
Pubmed

SOCS-1 binding to tyrosine 441 of IFN-gamma receptor subunit 1 contributes to the attenuation of IFN-gamma signaling in vivo.

IFNGR1 SOCS1

8.48e-06359219734231
Pubmed

Crystal structure of the WFIKKN2 follistatin domain reveals insight into how it inhibits growth differentiation factor 8 (GDF8) and GDF11.

MSTN GDF11

8.48e-06359230814254
Pubmed

Regulation of cytokine-driven functional differentiation of CD8 T cells by suppressor of cytokine signaling 1 controls autoimmunity and preserves their proliferative capacity toward foreign antigens.

IFNGR1 SOCS1

8.48e-06359220519645
Pubmed

Myostatin regulates fiber-type composition of skeletal muscle by regulating MEF2 and MyoD gene expression.

MSTN MEF2C

8.48e-06359219129464
Pubmed

The effects of concurrent training order on body composition and serum concentrations of follistatin, myostatin and GDF11 in sarcopenic elderly men.

MSTN GDF11

8.48e-06359232035222
Pubmed

MACF1 links Rapsyn to microtubule- and actin-binding proteins to maintain neuromuscular synapses.

RAPSN MACF1

8.48e-06359230842214
Pubmed

Structural basis for potency differences between GDF8 and GDF11.

MSTN GDF11

8.48e-06359228257634
Pubmed

Relationship of muscle function to circulating myostatin, follistatin and GDF11 in older women and men.

MSTN GDF11

8.48e-06359230165829
Pubmed

Conditionals by inversion provide a universal method for the generation of conditional alleles.

SCN9A MSTN GDF11

1.32e-052759323918385
Pubmed

Role of tyrosine 441 of interferon-gamma receptor subunit 1 in SOCS-1-mediated attenuation of STAT1 activation.

IFNGR1 SOCS1

1.69e-05459215522878
Pubmed

Characterization of follistatin-related gene as a negative regulatory factor for activin family members during mouse heart development.

MSTN GDF11

1.69e-05459217878677
Pubmed

Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11.

MSTN GDF11

1.69e-05459218596030
Pubmed

Differential antagonism of activin, myostatin and growth and differentiation factor 11 by wild-type and mutant follistatin.

MSTN GDF11

1.69e-05459218535106
Pubmed

The intercellular adhesion molecule (ICAM) family of proteins. New members and novel functions.

ICAM5 ICAM3

1.69e-0545929638475
Pubmed

A novel serine-rich motif in the intercellular adhesion molecule 3 is critical for its ezrin/radixin/moesin-directed subcellular targeting.

ICAM5 ICAM3

1.69e-05459211784723
Pubmed

Activated apoptotic cells induce dendritic cell maturation via engagement of Toll-like receptor 4 (TLR4), dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN), and β2 integrins.

ICAM5 ICAM3

2.82e-05559222396536
Pubmed

Overexpression of Latent TGFβ Binding Protein 4 in Muscle Ameliorates Muscular Dystrophy through Myostatin and TGFβ.

MSTN GDF11

2.82e-05559227148972
Pubmed

Cooperation between MEF2 and PPARgamma in human intestinal beta,beta-carotene 15,15'-monooxygenase gene expression.

MEF2C BCO1

2.82e-05559216504037
Pubmed

Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.

IFNGR1 ICAM5 ICAM3 SOCS1

4.05e-0511259420331378
Pubmed

BMP-11 and myostatin support undifferentiated growth of human embryonic stem cells in feeder-free cultures.

MSTN GDF11

4.23e-05659219751112
Pubmed

SOCS-1 protects against Chlamydia pneumoniae-induced lethal inflammation but hampers effective bacterial clearance.

IFNGR1 SOCS1

4.23e-05659218322213
Pubmed

Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.

BRD9 BCL11A

4.23e-05659223644491
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

TMEM132A MACF1 HECTD1 SSPOP

7.23e-0513059412421765
Pubmed

Autoregulation of neurogenesis by GDF11.

MSTN GDF11

7.87e-05859212546816
Pubmed

A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea.

MSTN GDF11

7.87e-05859231187730
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

ZFHX4 SUGP2 PARVA MACF1 SSB

1.18e-0428259523667531
Pubmed

Autoantibody of NRIP, a novel AChR-interacting protein, plays a detrimental role in myasthenia gravis.

RAPSN MACF1

1.26e-041059233773096
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

IFNGR1 CELSR1 FBXO22 ERO1B MRC2 TMEM132A CD44 HECTD1 POFUT2

1.80e-04120159935696571
Pubmed

Silencing suppressor of cytokine signaling-1 (SOCS1) in macrophages improves Mycobacterium tuberculosis control in an interferon-gamma (IFN-gamma)-dependent manner.

IFNGR1 SOCS1

1.85e-041259221622562
Pubmed

Electronic medical records and genomics (eMERGE) network exploration in cataract: several new potential susceptibility loci.

GAN MEF2C

2.18e-041359225352737
Pubmed

A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea.

CELSR1 CD44

2.54e-041459229784671
Pubmed

The NLRP12 inflammasome recognizes Yersinia pestis.

IFNGR1 NLRP12

2.54e-041459222840842
Pubmed

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.

CELSR1 SSPOP

2.93e-041559220473291
Pubmed

Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2.

MSTN GDF11

2.93e-041559224019467
Pubmed

Polymorphisms in innate immunity genes and risk of childhood leukemia.

ICAM5 ICAM3 SOCS1 MUC7

4.22e-0420659420438785
Pubmed

Risk of meningioma and common variation in genes related to innate immunity.

ICAM5 ICAM3 SOCS1 MUC7

4.29e-0420759420406964
Pubmed

Common variation in genes related to innate immunity and risk of adult glioma.

ICAM5 ICAM3 SOCS1 MUC7

4.37e-0420859419423540
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

SUGP2 PARVA RBM6 HECTD1

4.70e-0421259433853758
Pubmed

Developmental diversification of cortical inhibitory interneurons.

CELSR1 BCL11A MEF2C

5.07e-049159329513653
Pubmed

Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments.

RAPSN MEF2C

5.27e-042059234091985
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP31 SUGP2 VPS8 MACF1 BCL11A

6.38e-0440759512693553
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

VPS8 MACF1 PCNX1

6.87e-041015939872452
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

USP31 MTMR14 DHX38 PCNX1 SSB

7.35e-0442059528065597
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

LRRC37A LRRC37A3 SSPOP

7.69e-041055939628581
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

SUGP2 DHX38 RBM6 MACF1 SSB HECTD1

8.29e-0465359622586326
Pubmed

Construction of a human full-length cDNA bank.

CD44 SSB UQCRH

9.27e-041125937821789
Pubmed

Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling.

CD44 MSTN GDF11

1.05e-0311759322682244
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

MTMR14 MRC2 INPP5B VPS8

1.41e-0328559434369648
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DHX38 TMEM132A MACF1 ZNF407 HECTD1

1.50e-0349359515368895
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

SUGP2 DHX38 PARVA MACF1 SSB

1.56e-0349859536634849
Pubmed

Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects.

GAN BCO1

1.62e-033559219844255
CoexpressionAtlasB cells, B.Fo.PC, IgD+ IgM+ CD19+ CD43- CD5- CD23+, Peritoneal Cavity, avg-3

ERO1B BCL11A FCRLA MEF2C

1.42e-0553594GSM538198_100
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

CELSR1 LRRC37A2 RBM6 ZNF407 POFUT2 ST14

2.22e-0719459688db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

CELSR1 LRRC37A2 RBM6 ZNF407 POFUT2 ST14

2.22e-07194596a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

CELSR1 TMEM132A BCL11A FCRLA MEF2C

2.91e-061685958e025bb0541746e232b77ac0e31412ae71420c47
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B|GI_small-bowel / Manually curated celltypes from each tissue

CELSR1 TMEM132A BCL11A FCRLA MEF2C

2.91e-061685955535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CELSR1 LRRC37A2 RBM6 ZNF407 POFUT2

2.99e-06169595665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CELSR1 LRRC37A2 RBM6 ZNF407 POFUT2

2.99e-061695956614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERO1B INPP5B BCL11A FCRLA MEF2C

3.45e-0617459559ccc5a82507463e0a316ba6286cb25ec1a4091b
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERO1B ICAM3 DDX3Y FCRLA MEF2C

4.66e-06185595e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B MACF1 BCL11A FCRLA MEF2C

5.04e-061885951f07e3ab87173426fe0c429f5c084fb3425effd3
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B MACF1 BCL11A FCRLA MEF2C

5.04e-0618859585746f95319e494efdc1bbc24331698688d3a900
ToppCell10x5'-GI_large-bowel-Lymphocytic_B-GC_B_(II)|GI_large-bowel / Manually curated celltypes from each tissue

MTMR14 BCL11A FCRLA MEF2C ST14

5.30e-06190595fee64bacbb330d04dc1dc63909838f2c605d9f1f
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-pDC|bone_marrow / Manually curated celltypes from each tissue

SCN9A BCL11A FCRLA MEF2C ST14

5.30e-06190595dde0e34f6a06cdbbb65c86472360c09f0279a572
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic|bone_marrow / Manually curated celltypes from each tissue

SCN9A BCL11A FCRLA MEF2C ST14

5.30e-061905956892c603037b61ef88d6ca01b7592dc0d347d63b
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MTMR14 SOCS1 BCL11A FCRLA MEF2C

6.01e-06195595cccc9c70bb8f6df8c6ab94534c17475af1d3e224
ToppCellsevere-pDC|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SCN9A BCL11A FCRLA MEF2C ST14

6.48e-0619859522da4a29b9ff8b94d98bc69b4632a2a58d5dd9e6
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ANGPTL2 ZFHX4 MRC2 SCN9A GDF11

6.64e-06199595a13f4b8a039304e685464cc8879659824cad5a3e
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ERO1B BCL11A FCRLA MEF2C

4.45e-05148594b78dac56b333bf901136ccafb0999f345e978f51
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ICAM5 TMEM132A GSG1L RNF39

4.68e-051505949d5bbdca19da60e1a2121ef64ec8e1375a5dbf6d
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ERO1B BCL11A FCRLA MEF2C

4.81e-05151594ee56b88c56c3b6a5ec9644c43cae521ea0e05920
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ERO1B BCL11A FCRLA MEF2C

4.81e-051515942c239b09970acbaa90c5ebe1097f453c516f868e
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ERO1B BCL11A FCRLA MEF2C

4.93e-05152594b750302d442160a1007659c2386ac90282bf95d2
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CELSR1 BCL11A FCRLA MEF2C

5.19e-05154594020697ae8463b18f9b4270c404f52ce4c0e90135
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CELSR1 BCL11A FCRLA MEF2C

5.46e-051565944e4b94580969a9736ca28df79715535a4bd1f9b2
ToppCelldroplet-Thymus-nan-18m-Myeloid-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

5.59e-05157594a9e077f686382303f0437ebfa4f11d273ba9fe40
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CELSR1 INPP5B ICAM3 BCL11A

5.59e-05157594d12f343454202da86a06d0369f8ffe5662cd091b
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRIM58 BCL11A FCRLA MEF2C

6.32e-05162594fc313fb2c55957faa8c9ca4023b3fce63527c267
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRIM58 BCL11A FCRLA MEF2C

6.32e-05162594002fac3c5c3030950f9eb9e887d59902586d8452
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRIM58 BCL11A FCRLA MEF2C

6.32e-0516259408b7f06580d516307516d5475a5dae0fa040f1a4
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRIM58 BCL11A FCRLA MEF2C

6.32e-051625941fda21a303a08aff6f97819cd8766cd18784d8bc
ToppCellHealthy_Control-Lymphoid-Plasma|Healthy_Control / Condition, Lineage, Cell class and cell subclass

ZNF597 FBXO22 SCN9A MEF2C

6.47e-051635942913ccdd4613472cd82077d4993e1d9f8b223398
ToppCellHealthy_Control-Lymphoid-Plasma-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

ZNF597 FBXO22 SCN9A MEF2C

6.47e-05163594b589ff57d58dcb215ee3b5a10d81f43e5752a196
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_naive-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RBM6 BCL11A FCRLA MEF2C

6.78e-051655948003fd2aa3f5c9d0e99054af4ad2d79a4a3c4829
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP31 BCL11A FCRLA MEF2C

6.78e-0516559422293c6b55f44636440cd737efb786ff5de3373d
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CELSR1 BCL11A FCRLA MEF2C

6.78e-05165594fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCellfacs-Heart-RA-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA ST14

6.94e-05166594fc2cf67311c86fda75b35fcd4768b6f6f14c59d0
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|367C / Donor, Lineage, Cell class and subclass (all cells)

ZNF597 LRRC37A MTMR14 ST14

6.94e-05166594430d604f5bef9fae20dc81492e6695616f6701a3
ToppCellfacs-Heart-RA-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA ST14

6.94e-0516659433a6876d06e26176135a73a77c19e634ec53f7ce
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

7.11e-05167594691f3589de0f8c13f9137812cfa9040c07d237b4
ToppCellmild-Lymphocytic-B_cells_2|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

BCL11A FCRLA MEF2C BCO1

7.11e-051675940811f7559c2a7151693771e52e14af3978997118
ToppCellfacs-Thymus-nan-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCL11A FCRLA MEF2C ST14

7.27e-05168594d72cd8238fa793bb3e4add4c59eaaaadcea9930d
ToppCelldroplet-Thymus-nan-21m-Myeloid-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCL11A FCRLA GDF11 MEF2C

7.27e-0516859469dd747be46e7fbcec571cddd6dee374b9c2507a
ToppCellfacs-Thymus-nan-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCL11A FCRLA MEF2C ST14

7.27e-05168594c34c52165485f612add7a3e35a175d5a6e365e7c
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B CD44 FCRLA SSPOP

7.27e-05168594bc7d5f0e5d222922eaf1c8e8c87aab189209d6b6
ToppCellfacs-Thymus-nan-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCL11A FCRLA MEF2C ST14

7.27e-05168594d2afc097ae1243574210be6a751685f949ea941a
ToppCellB_cell|World / lung cells shred on cell class, cell subclass, sample id

ICAM3 BCL11A FCRLA MEF2C

7.61e-05170594cec4090ba6a9c934d5f6f9e4aa7823f3713319b7
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCN9A BCL11A FCRLA MEF2C

7.61e-05170594b49f7c8a27078de2137ed04f74cfee30729cfa5e
ToppCelldroplet-Fat-Gat-18m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

7.61e-051705945185187ecf26b4c9eaa0c01ad52697ab8d075cc7
ToppCelldroplet-Thymus-nan-21m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD44 BCL11A FCRLA MEF2C

7.61e-0517059429deb285d5a82c0abcc108012ca42f4b4b4d9e19
ToppCelldroplet-Thymus-nan-21m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD44 BCL11A FCRLA MEF2C

7.61e-05170594dc35d66a9a9fe6cdd7f4ec0fe7efa49d02f2b5b2
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCN9A BCL11A FCRLA MEF2C

7.61e-0517059492e765ae0d3adb38d3b22fddb873fd5ccad3fd44
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCN9A BCL11A FCRLA MEF2C

7.61e-051705949f8b215caa1afa3cd7104c06fca7cfd790640f66
ToppCellfacs-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

7.79e-05171594a31c23406cf6d6a17358a8fb41d392a7fb0306e0
ToppCellfacs-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

7.79e-0517159443d8fd9b9546e84a652564fe96b514b34b06262b
ToppCelldroplet-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

8.15e-05173594886ac1b98f709ad7131df778b83712bf8ed313de
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

8.33e-051745942f4bc0275cbcaa830d04a4c76e042456908d2277
ToppCellASK452-Immune-B_cell|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

LRRC37A3 INPP5B LRRC37A2 BCL11A

8.33e-0517459469723f5666abc3af5f0431901a60246c9915ef81
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

8.33e-0517459401eff218e71a04201189a0313aaf91437fffed95
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

8.33e-05174594f0f6d135e1fb4c15022be103b00d8d5456515a18
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|normal_Lymph_Node / Location, Cell class and cell subclass

LRRC37A LRRC37A3 SCN9A BCL11A

8.52e-0517559429fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B CD44 FCRLA MEF2C

8.71e-0517659435610e7ac9902687e222641202409bab279c3998
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B FCRLA MEF2C ST14

8.71e-05176594606704098bfdf8bfef740a3544a372fae1e75969
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-B_cell-B_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERO1B BCL11A FCRLA MEF2C

8.71e-0517659427c132e9852717cbc345af7a1fc390e9ea589416
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B FCRLA MEF2C ST14

8.71e-05176594acb9e29773030f6452a069f8f7e53eab68ab7bd3
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-B_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERO1B BCL11A FCRLA MEF2C

8.71e-05176594259d1864fb0a6d2feddc90bc715e2bccbb373792
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B CD44 FCRLA SSPOP

8.90e-0517759441cbb2c109eaa7be366fc0510cce64abc06837b4
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-T_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 RAPSN IQCC RNF39

8.90e-05177594baf78a8dad55f124f56585f88b10b58c0269680f
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

9.10e-05178594ba5a477257877f4a15a91c1762ffcc6f2e9f7357
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

9.10e-051785945634c1fbc817758092af4feafff94d107412d89b
ToppCellfacs-GAT-Fat-3m-Lymphocytic-B_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

9.10e-051785945b6f7e8a930c239db1f31edfb61b2b9228d28663
ToppCelldroplet-Liver-Hepatocytes-21m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCL11A FCRLA GDF11 ST14

9.10e-051785944289e435d465b7a1490d13bf05278f4ed77d69cd
ToppCellmild-Lymphocytic-B_cells_2|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

BCL11A FCRLA MEF2C BCO1

9.10e-05178594c6fb21401ad802a57e4e4f5a1723c42779fdb33e
ToppCellnormal_Lung-B_lymphocytes|normal_Lung / Location, Cell class and cell subclass

SCN9A BCL11A FCRLA MEF2C

9.29e-051795945b89193486100b6754c1c5eca3105ea955805eae
ToppCellcellseq-Immune-Lymphocytic_B-Lymphocytic_B|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ICAM3 BCL11A FCRLA MEF2C

9.50e-05180594cd04d7bf92986a5b8a0193c9b92ec47da3929bac
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-FCRL4+_Memory_B|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IFNGR1 CD44 FCRLA MEF2C

9.50e-05180594eedb6d89680f968167afb1dcd132c9de9096b50f
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A BRD9 MACF1 MEF2C

9.50e-05180594dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCellCOVID-19-kidney-Bcells|kidney / Disease (COVID-19 only), tissue and cell type

CD44 BCL11A FCRLA MEF2C

9.50e-051805945650fc7ebcdf5e0be9a217a58d36a8386d59fd1b
ToppCellfacs-MAT-Fat-24m-Lymphocytic-B_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

9.50e-05180594711719219bcbafdd505790eda895e7a33f21bed2
ToppCellcellseq-Immune-Lymphocytic_B|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ICAM3 BCL11A FCRLA MEF2C

9.50e-05180594663a800ab70e7ab7d13183417f9c1ed36907aa5e
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A BRD9 MACF1 MEF2C

9.50e-05180594423454e3390080ae03bb3cbb267255ebfe4df080
ToppCellSevere-Lymphoid-pDC|Severe / Condition, Lineage, Cell class and cell subclass

SCN9A BCL11A FCRLA MEF2C

9.70e-051815942caecb7c5dcdad46fd02b4ffb73cb613ce835187
ToppCellfacs-SCAT-Fat-18m-Lymphocytic-B_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

9.70e-051815943510e0ecd4f098e8553946c44c2a49587d543755
ToppCell(1)_B_cells-(1)_B_CD27pos|(1)_B_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

CD44 SOCS1 DDX3Y UQCRH

9.70e-05181594d2476956ca13f9234d7e77c3ee432dd54eebeac4
ToppCell10x5'-Liver-Lymphocytic_B-Memory_B_cells|Liver / Manually curated celltypes from each tissue

CELSR1 BCL11A FCRLA MEF2C

9.70e-05181594a9f4df288c34e3b2b6ed861ac6cda970c3ee08b1
ToppCellSevere-Lymphoid-pDC-|Severe / Condition, Lineage, Cell class and cell subclass

SCN9A BCL11A FCRLA MEF2C

9.70e-05181594277ce4c49121da0990a5933b19d2c6af9bbe253e
ToppCellcellseq-Immune-Lymphocytic_B-Lymphocytic_B-B|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ICAM3 BCL11A FCRLA MEF2C

9.91e-05182594dc6b5ce410c1a7cade60ae17cbbe8548c088cba8
ToppCellnormal-na-Lymphocytic_B-B_mem-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

DDX3Y BCL11A FCRLA MEF2C

9.91e-05182594ee36ea6cb9a5a08aeb83f2b7a249255f0b1a9870
ToppCelldroplet-Mammary_Gland-nan-21m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

9.91e-0518259497f393549c7718a32af55b2377801bfebb10cc52
ToppCellE18.5-samps-Mesenchymal-Myofibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

ANGPTL2 SUGP2 C11orf96 BCL11A

1.01e-04183594de08f9ea02b7244d5a8788064631d10f06565337
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-plasma_cell-plasma_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERO1B FCRLA MEF2C ST14

1.01e-041835940f6799e4f058bed546fe5759502430f4a19635da
ToppCellfacs-Thymus-Flowthrough-24m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

1.01e-041835940513bb73552bfee609877d924fa97684200f595c
ToppCellfacs-Thymus-Flowthrough-24m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

1.01e-041835946eeef55071ae25a61616df4fcfb2cea560aa7923
ToppCelldroplet-Mammary_Gland-nan-21m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

1.01e-04183594e7038532a6e159bb3e383cdd9c44b3b7f21c0c01
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

1.01e-04183594544939a0bfef082d361d88ef70d6f0923b8d9af9
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B CD44 FCRLA MEF2C

1.01e-04183594edb0069c66b1465dcc0bb5881417c6b17184fd74
ToppCellfacs-Thymus-Flowthrough-24m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B BCL11A FCRLA MEF2C

1.01e-0418359485b2335fa938a94e74251bd8d99de1bd21265ac9
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-plasma_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERO1B FCRLA MEF2C ST14

1.01e-041835948ef5223e46f1fd81a856261248cc77e7c7e72ef6
ToppCell3'_v3-blood-Lymphocytic_B-Memory_B_cells|blood / Manually curated celltypes from each tissue

CELSR1 BCL11A FCRLA MEF2C

1.01e-04183594e3a418b745d7f040adf47be9e1043b945cae47ed
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS15 ZFHX4 SCN9A SSPOP

1.03e-041845942cbed6462fea2622871bb7e49b0df3d984239281
ToppCellwk_20-22-Hematologic_Lymphocytic-B-CD5+_CCL22+_mature_B|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ICAM3 CD44 BCL11A FCRLA

1.03e-041845945bb775253a10a14360b06a46aba46d162a9bd1f8
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B CD44 FCRLA MEF2C

1.03e-0418459482d2daa39e3c31a74c08a5d77366740b87beb2fb
DrugPindolol [13523-86-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A

RAPSN ERO1B MRC2 PARVA PCNX1 MEF2C

1.20e-051975962238_UP
Drug(-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; HL60; HT_HG-U133A

ZFHX4 IQCC MRC2 CD44 POFUT2 MEF2C

1.30e-052005963081_UP
DrugPropofol [2078-54-8]; Up 200; 22.4uM; MCF7; HT_HG-U133A

ANGPTL2 ERO1B MRC2 SOCS1 ZNF407

1.24e-041875953386_UP
Drug3-sulfoglucuronic acid

ICAM5 CD44

1.37e-047592CID000130628
DrugMebeverine hydrochloride [2753-45-9]; Up 200; 8.6uM; PC3; HT_HG-U133A

INPP5B TMEM132A PARVA PCNX1 BCL11A

1.44e-041935957147_UP
DrugNorfloxacin [70458-96-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A

SUGP2 MRC2 CD44 PCNX1 XRCC2

1.44e-041935955985_DN
DrugNorfloxacin [70458-96-7]; Down 200; 12.6uM; PC3; HT_HG-U133A

IFNGR1 TRIM58 CD44 PCNX1 MEF2C

1.47e-041945957283_DN
DrugClorsulon [60200-06-8]; Down 200; 10.6uM; PC3; HT_HG-U133A

DHX38 TMEM132A PCNX1 XRCC2 GDF11

1.51e-041955957264_DN
DrugMethacholine chloride [62-51-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A

ANGPTL2 IQCC SOCS1 XRCC2 MEF2C

1.51e-041955953452_UP
DrugNapelline [5008-52-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A

ZFHX4 PARVA DDX3Y PCNX1 POFUT2

1.54e-041965956824_UP
DrugCimetidine [51481-61-9]; Down 200; 15.8uM; PC3; HT_HG-U133A

TMPRSS15 FBXO22 GAN ZNF407 MEF2C

1.54e-041965954063_DN
DrugMianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A

SUGP2 INPP5B TMEM132A ZNF407 PCNX1

1.54e-041965956260_UP
DrugPNU-0251126 [267429-19-6]; Up 200; 1uM; PC3; HT_HG-U133A

TMPRSS15 MRC2 ZNF407 MUC7 MEF2C

1.54e-041965953692_UP
DrugSulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; HL60; HT_HG-U133A

ANGPTL2 MRC2 ICAM5 SOCS1 ZNF407

1.54e-041965952560_UP
DrugAlcuronium chloride [15180-03-7]; Up 200; 5.4uM; MCF7; HT_HG-U133A

ERO1B MRC2 MYRIP BCL11A POFUT2

1.54e-041965954409_UP
DrugTrimeprazine tartrate [4330-99-8]; Down 200; 5.4uM; HL60; HT_HG-U133A

ZFHX4 ICAM5 PCNX1 MEF2C ST14

1.54e-041965952736_DN
DrugEucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; HL60; HT_HG-U133A

ANGPTL2 ZFHX4 MRC2 ICAM5 ZNF407

1.58e-041975952556_UP
DrugLY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A

IQCC ICAM5 INPP5B CD44 PCNX1

1.62e-041985956976_UP
DrugFluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; HL60; HT_HG-U133A

ANGPTL2 ICAM5 MYRIP SOCS1 ST14

1.62e-041985952521_UP
DrugDiperodon hydrochloride [537-12-2]; Down 200; 9.2uM; PC3; HT_HG-U133A

ERO1B INPP5B PARVA SCN9A MEF2C

1.62e-041985954498_DN
DrugButirosin disulfate salt [51022-98-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A

RAPSN IQCC INPP5B PARVA PCNX1

1.62e-041985956080_DN
DrugFuraltadone hydrochloride [3759-92-0]; Up 200; 11uM; PC3; HT_HG-U133A

FBXO22 ANGPTL2 ERO1B PARVA MUC7

1.62e-041985953756_UP
DrugTetrahydroxy-1,4-quinone monohydrate [319-89-1]; Down 200; 21uM; PC3; HT_HG-U133A

TMPRSS15 CELSR1 FBXO22 ERO1B ST14

1.62e-041985954078_DN
DrugPF-01378883-00 [351320-41-7]; Up 200; 10uM; PC3; HT_HG-U133A

SCN9A SOCS1 ZNF407 PCNX1 MEF2C

1.66e-041995956410_UP
DrugProguanil hydrochloride [637-32-1]; Down 200; 13.8uM; MCF7; HT_HG-U133A

FBXO22 SUGP2 MRC2 CD44 XRCC2

1.66e-041995955506_DN
DrugGly-His-Lys acetate salt; Down 200; 1uM; PC3; HT_HG-U133A

CELSR1 INPP5B TMEM132A PARVA BCL11A

1.66e-041995956560_DN
Drugiloprost; Up 200; 1uM; SKMEL5; HG-U133A

SUGP2 PARVA SOCS1 BCL11A ST14

1.66e-04199595496_UP
DrugAlbendazole [54965-21-8]; Up 200; 15uM; MCF7; HT_HG-U133A

CELSR1 INPP5B DDX3Y BCL11A MEF2C

1.66e-041995953164_UP
DrugDiphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A

ERO1B ZFHX4 CD44 ZNF407 MEF2C

1.66e-041995954765_DN
DrugNystatine [1400-61-9]; Down 200; 4.4uM; MCF7; HT_HG-U133A

SUGP2 SOCS1 GAN PCNX1 XRCC2

1.69e-042005954807_DN
DrugSpiramycin [8025-81-8]; Up 200; 4.8uM; HL60; HT_HG-U133A

FBXO22 ANGPTL2 ZFHX4 TRIM58 ST14

1.69e-042005952558_UP
DrugGabazine [105538-73-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A

TMPRSS15 ANGPTL2 ERO1B MRC2 PCNX1

1.69e-042005954820_UP
Drug(R)-(+)-Atenolol [56715-13-0]; Down 200; 15uM; MCF7; HT_HG-U133A

SUGP2 MTMR14 MRC2 DHX38 PCNX1

1.69e-042005954841_DN
DrugNaringin hydrate [11032-30-7]; Up 200; 6.6uM; PC3; HT_HG-U133A

TMPRSS15 PARVA GAN ZNF407 PCNX1

1.69e-042005954605_UP
DrugTetrandrine [518-34-3]; Up 200; 6.4uM; HL60; HT_HG-U133A

ANGPTL2 ERO1B ZFHX4 MEF2C ST14

1.69e-042005952520_UP
Diseasevertebral hypersegmentation and orofacial anomalies (implicated_via_orthology)

MSTN GDF11

3.80e-062582DOID:0070418 (implicated_via_orthology)
Diseasearthritis

GAN BCO1

1.14e-053582EFO_0005856
Diseasebutyrylcholinesterase measurement

NLRP12 TRIM58

5.67e-056582EFO_0004571
Diseaseprotein-tyrosine sulfotransferase 2 measurement

NLRP12 RAPSN

1.06e-048582EFO_0801971
Diseaseintercellular adhesion molecule 5 measurement

ICAM5 ICAM3

2.92e-0413582EFO_0008164
Diseaseplatelet-to-lymphocyte ratio

RAPSN TRIM58 ICAM5 ICAM3 MEF2C

7.36e-04363585EFO_0008446
DiseaseICAM-1 measurement

ICAM5 ICAM3

1.02e-0324582EFO_0004520
Diseaseloneliness measurement

RAPSN SUDS3 MACF1

1.89e-03124583EFO_0007865

Protein segments in the cluster

PeptideGeneStartEntry
REREHCDTEGEADDF

BRD9

96

Q9H8M2
RDHFCELDDERSPAA

ERO1B

161

Q86YB8
RDGSEEDFHLDCRHE

GSG1L

281

Q6UXU4
RDCLQALEDGHDTSS

ANGPTL2

276

Q9UKU9
EDFTGEHCEVDARSG

CELSR1

1391

Q9NYQ6
CFADIHRSRGDLETA

RAPSN

251

Q13702
ELCDERVSSRSHTEE

UQCRH

51

P07919
RTTGELEQEDDSCHR

IQCC

236

Q4KMZ1
ADSETFISLEECRGH

FBXO22

106

Q8NEZ5
CHRRSLQEDEEGFSR

LRRC37A3

1606

O60309
CHRRSLQEDEEGFSR

LRRC37A2

1606

A6NM11
CHRRSLQEDEEGFSR

LRRC37A

1606

A6NMS7
FSGDLDDQTCREDLH

SSB

236

P05455
DVTEEDCALRSGDTH

MTMR14

176

Q8NCE2
LHCEDGSDEADCVRF

TMPRSS15

666

P98073
AEAEGHRDTCDEDSV

BCL11A

576

Q9H165
HRDTCDEDSVAGESD

BCL11A

581

Q9H165
FCHDEDSSDQSDLSR

PCNX1

596

Q96RV3
DDRRSFFCDATLDVD

ICAM5

376

Q9UMF0
NFDRSRHDDDDIRGC

MRC2

771

Q9UBG0
SCSSSYDGSDREDHR

MEF2C

426

Q06413
DEEDSGREIFLSCSH

MACF1

2266

Q9UPN3
RDDHGAPFSCRTELD

ICAM3

181

P32942
DLGCLRRDFHSDTSA

PPP1R3A

481

Q16821
CFSFSEGRERDHELR

MUC7

16

Q8TAX7
RGDRDLHCTESQSEA

HECTD1

2291

Q9ULT8
ENEDERDRHLSFSGS

CD44

281

P16070
CHTEDDLTDAREAGF

FCRLA

46

Q7L513
SSFREESRFCDAHLV

GAN

21

Q9H2C0
SRRNLGLDCDEHSSE

GDF11

296

O95390
LRSEFEHIRDCLDTG

INPP5B

856

P32019
DSICSRRGTSEEHEA

KATNA1

311

O75449
CTSIHGDRSQRDREE

DDX3Y

466

O15523
VTDSGRHILEDSCAE

SDE2

286

Q6IQ49
DHSRNGFDTDSSCLE

IFNGR1

406

P15260
SHADFRGRDLSDLDF

RBM6

191

P78332
CDGREDCLDGSDERH

SSPOP

2411

A2VEC9
AEASDEAERRARGCH

TMEM132A

526

Q24JP5
DEFRSRHLNSTDDAD

POFUT2

251

Q9Y2G5
RDFGLDCDEHSTESR

MSTN

266

O14793
ADDEHSIFGDNESRR

SCN9A

571

Q15858
EFLCSPDDDSRHSER

VPS8

861

Q8N3P4
LSGRHERDAFDTLFD

PARVA

241

Q9NVD7
HLDGSRESFDCLFEL

SOCS1

136

O15524
SEEQRDRASDCHGAP

BCO1

531

Q9HAY6
RAFISRDCGSDAAED

C11orf96

71

Q7Z7L8
SLGARTCDDDLTEQH

ZFHX4

1086

Q86UP3
RSFDLASCDERGSDL

ST14

261

Q9Y5Y6
ECGRDLEFSHSDSRD

SUGP2

106

Q8IX01
EDASIHRLEGTDLDC

DHX38

6

Q92620
SEEPSHASRRLCDVD

XRCC2

206

O43543
ESAQHEDGRDSEACR

ZNF213

31

O14771
KSHDEDSERCSDDGD

ZNF597

316

Q96LX8
RSFCDTDDLETVHES

USP31

376

Q70CQ4
TCDFSSMSRRDLDEH

ZNF407

561

Q9C0G0
DERSCRGRESDEDTE

SUDS3

36

Q9H7L9
CARHGEDLSRFCEED

TRIM58

96

Q8NG06
CRDSSGEDADDEESH

RNF39

296

Q9H2S5
SADGEDRARCSAGAH

NLRP12

671

P59046
TELEDAARCIHSGTD

MYRIP

716

Q8NFW9